ライフサイエンスコーパス: as yet

1 view of clinical similarity, but not proven as yet.

2 le investigation of their combined potential as yet.

3 ngle-phase multiferroic materials discovered as yet.

4 e is no synthesis of these factors available as yet.

5 phenotypes have no physiological explanation as yet.

6 leaving mechanism has not been substantiated as yet.

7 ver, the technique does have limitations and as yet a general experimental method has not been realiz

8 However, there is as yet a paucity of statistical methodologies to detect

9 As yet, a comprehensive evaluation of the diffusivity pa

10 alternative metabolic pathways involved, but as yet, a direct analysis of the relative redistribution

11 s that give rise to sound symbolism are not, as yet, altogether clear.

12 onstrated in a number of systems(13-15), but as yet an accurate assessment of their fidelities using

13 ever, none of these strategies has delivered as yet, and important challenges remain in the developme

14 o develop statistical awareness and thinking as yet another critical judgment skill they bring to the

15 ll characterized, very little information is as yet available in Vespidae, although this family repre

16 living species and species complexes cannot as yet be reliably extended into deep time.

17 There has as yet been little examination of one potential substrat

18 vertheless, no mid-trimester biomarkers have as yet been proven useful for prediction of PE.

19 ian influenza but no comprehensive study has as yet been reported comparing their innate immunity phe

20 is well documented in metazoans but has not as yet been reported for plant receptor kinases.

21 tion in this burgeoning field which has not, as yet, been fully resolved, relates to the precise mech

22 can be parallelized and their accuracy has, as yet, been only limited by the flexibility of the wave

23 arget for drug discovery, efforts which have as yet brought little success.

24 As yet, Electronic Circular Dichroism that uses electron

25 with Th2 pathology; though, the mechanism is as yet elusive.

26 rmed pathogenetic understanding, but no cure as yet exists.

27 rmore, computational dynamo simulations have as yet failed to produce a magnetostrophic dynamo, which

28 cal and physiological diversity of ants, but as yet few studies have investigated the genetics of ant

29 for the next wave of GWAS, few studies have as yet focused on rare genetic variants in the study of

30 No treatment exists as yet for FRDA cardiomyopathy.

31 mechanism of TSLP profibrotic effects is not as yet fully understood, although the data suggest that

32 the genetic ancestry of individuals from two as yet genetically unstudied cultural traditions in Esto

33 nome sequencing and assembly efforts in this as yet genomically neglected group of crucifer plants.

34 As yet, high-fidelity experimental techniques for charac

35 As yet, however, insight into the stoichiometric and ene

36 As yet, however, no unifying model has been found to und

37 As yet, human studies have provided little to resolve th

38 fections or malignancies without a known (or as-yet-identified) genetic predisposition.

39 As yet, in crocodilians, topographical representations h

40 inella chromatophora as a consequence of the as yet incomplete integration of host and chromatophore

41 rns should be distilled from the diverse and as-yet inconclusive results of existing studies, and mor

42 This current review explores selected and as yet insufficiently investigated frontiers in current

43 ding of the photoswitching mechanism, which, as yet, is absent.

44 As yet, it is unknown whether this reduction precedes or

45 lmonary disease overlap syndrome (ACOS), but as yet, it lacks a precise definition.

46 n demonstrated for some tasks, but little is as yet known about the developmental curve of cognitive

47 olidation also depend on BLA activity is not as yet known.

48 ent bearing non-walking appendages, features as-yet known in all vicissicaudatans, but aglaspidids.

49 sociated non-coding-genes play an important, as yet largely unexplored, role in AD.

50 d micro-plastics are found in the ocean, but as yet little is known about their ultimate fate and the

51 As yet, little is known about the underlying mechanism.

52 As yet, methods for their detection have not spectroscop

53 As yet, models of autophagosomal fusion have not been ve

54 rminal center (GC) alters CD22 ligands, with as yet no ascribed biological consequence.

55 or adaptation in young and older adults, but as yet no direct comparisons of TDCS effects exist betwe

56 d emerging machine-learning tools, there are as yet no equivalent sensing platforms and large-scale d

57 There are as yet no licensed MERS vaccines or therapeutics.

58 There are as yet no licensed therapeutics for the COVID-19 pandemi

59 There is as yet no widely replicated assay in which to screen com

60 une evasion through multiple mechanisms, but as yet, no CAF-specific inhibitors are clinically availa

61 ble to define prognosis reliably, there are, as yet, no clear diagnostic or response-adjusted paramet

62 ant cause of global blindness and there are, as yet, no effective means of screening.

63 coupled hydrogen-bonding networks, there is, as yet, no method that can rigorously calculate the free

64 As yet, no models of these interactions in muscle exist.

65 As yet, no open source software is available for the aut

66 Since the KRAS oncoprotein is, as yet, not directly druggable, efforts to target KRAS m

67 aspects of BNR yield environmental responses as yet overlooked.

68 ele-specific syndrome causing defects in two as yet pathogenically unrelated functions, reproduction

69 mother centriole-derived basal body (BB) via as yet poorly characterized mechanisms.

70 r potential routes to therapy, but these are as yet poorly defined.

71 separation of cells based on complicated and as yet poorly understood cell phenotypes.

72 olution in the liquid cell during imaging is as yet poorly understood due to the generation of a comp

73 d the Parkin ubiquitin-like (Ubl) domain via as yet poorly understood mechanisms.

74 wasting of skeletal muscle and fat tissue by as yet poorly understood mechanisms.

75 after menarche, highlighting the central but as yet poorly understood role for sex-restricted anatomi

76 However, the as-yet poorly characterized contribution of host respons

77 tin folding, have been causally linked to an as-yet poorly defined syndrome that includes intellectua

78 This coordination is as-yet poorly understood, but proteins such as formins a

79 were associated with paediatric IBD, but not as yet replicated.

80 itions of tropomyosin on actin but have not, as yet, succeeded at determining key atomic-level contac

81 es performing fine disparity discrimination, as yet the earliest site for this task.

82 Intestinal inflammation is mediated by BFT, as yet the only known virulence factor of ETBF.

83 iagnostic for assessing wound condition, but as yet there are few technological options available to

84 oses are needed for COVID-19 infections, but as yet there is no convincing evidence of clinical effic

85 As yet, there are a few examples of privileged fuel chem

86 As yet, there are no standardized treatment options for

87 As yet, there has been no investigation into the effects

88 As yet, there is no effective vaccine against respirator

89 As yet, this multi-length-scale complexity cannot be ful

90 ription; however, no attempts have been made as yet to modulate mammalian transcription factors.

91 function of the biological lens, are unable as yet to provide such an implant with the requisite opt

92 amics they also represent a significant, and as yet unaccounted, marine geohazard.

93 ation densities (10 and 14 plants per m(2)), as yet unachievable in commercial farms with current hyb

94 unodeficiency virus type 1 (HIV-1) is a key, as-yet-unachieved goal of prophylactic HIV-1 vaccine str

95 Here we identify as-yet-unacknowledged anthropogenic biases in both the r

96 een before and annotate experiments that are as yet unannotated.

97 ulate PI metabolism may have significant and as yet unappreciated roles in leukemia.

98 transient ortho-quinols have a role in the, as yet uncharacterised, biosynthetic pathways around sal

99 s of the Candidate Phyla Radiation (CPR) and as yet uncharacterized Archaea.

100 -21beta position to be oxidized first, by an as yet uncharacterized enzyme.

101 om 10(5) to 10(6) biosynthetic gene clusters as yet uncharacterized for potential new therapeutic age

102 n important class of developmental proteins, as yet uncharacterized in vertebrates.

103 NA) intermediates can serve as substrates by as yet uncharacterized integration machinery.

104 protein 2 (NOD2) innate immune receptors by as yet uncharacterized ligands, which are presumed to be

105 of multiple RNA species including novel and as yet uncharacterized long noncoding transcripts with u

106 ontain novel alleles derived from extinct or as yet uncharacterized populations.

107 broad range of proteins, it may have other, as yet uncharacterized, downstream effects which could c

108 Wolbachia effectors and point to potential, as yet uncharacterized, links between known phenotypes i

109 Here, we report the identification of an as-yet uncharacterized silent gene cluster of the fungus

110 ing in single cells of peripheral tissues is as-yet uncharacterized.

111 short-chain fatty acids, neurotransmitters, as-yet-uncharacterized biochemicals, and derivatives of

112 ct from known virophages and that additional as-yet-uncharacterized virophages are likely present wit

113 The risk of zoonotic transmission of CWD is as yet unclear but a high priority must be to minimize f

114 However, it is as yet unclear how ROS signaling downstream of receptor

115 major risk factor in multiple sclerosis, via as yet unclear mechanisms.

116 ght perturbations of the CaM/KCNQ complex is as yet unclear.

117 host response to influenza infection through as-yet-unclear mechanisms.

118 rial taxa found in the human oral cavity are as yet uncultivated in vitro.

119 acterial candidate phyla radiation (CPR) and as yet uncultivated phyla belonging to the DPANN (Diaphe

120 covered 16S rRNA genes belonging to a novel, as-yet-uncultivated mycoplasma (lineage 'Mnola') in the

121 The as-yet uncultured filamentous bacteria "Candidatus Entot

122 ivation and characterization of species from as-yet-uncultured branches of the microbial tree of life

123 ND3, KCNB1, NOS1AP and HEY2) and others with as yet undefined cardiac function.

124 ng that P3H3 and/or SC65 mutations may cause as yet undefined EDS variants.

125 rom photoreceptors into RPE cells through an as yet undefined mechanism.

126 docycle entry at the G2-M transition as well as yet undefined roles for differentiation regulators (e

127 cellular respiration stimulates SaeRS via an as yet undefined signal molecule(s), resulting in increa

128 chanistic contributions to tumorigenesis are as yet undefined.

129 ion; however, any contribution of B cells is as yet undefined.

130 which new tools or approaches are needed are as yet undefined.

131 independent of this complex are evident but as yet undefined.

132 d representatives (candidate phyla) and from as-yet undefined lineages.

133 in GAS transmission and persistence and that as-yet-undefined factors are required for the transmissi

134 P(i) enters the SR via a Cl(-) pathway of an as-yet-undefined molecular nature.

135 ifs to antagonize human BST-2, suggesting an as-yet-undefined way that SIVgsn71 Vpu works against hum

136 This study should help uncover novel and as yet underappreciated functions of vertebrate beta-cat

137 dowry thus appears to be a coordinated, but as-yet underappreciated, aspect of the MZT.

138 ntrinsic or adaptive brain mechanisms is not as yet understood.

139 combinations, which allowed the inference of as yet undescribed effector functions.

140 rmation about the kinetic isotope effects of as yet undescribed enzymes, thus to make predictions as

141 ling dysfunction and nitric oxide deficiency as yet-undescribed early manifestations of tau pathobiol

142 We also report an as-yet-undescribed mechanism for lipase transport in euk

143 This makes it possible to 1) reveal as yet undetected precursor types in view of exploring t

144 ectron pocket, but whether there is another, as yet, undetected portion to the Fermi surface is unkno

145 In the transition zone, Sphingomonas, with as yet undetermined ecological characteristics, are rela

146 Through as yet undetermined mechanisms, circulating and dietary

147 ld be (re)cast in terms of these (and other, as yet undetermined) functional components, to establish

148 oids is bioinspired, and may also inform the as-yet undetermined biosynthesis of several congeners.

149 r active preclinical and clinical study with as-yet undetermined hydration number.

150 trolling BLM protein levels, but via another as-yet undetermined mechanism.

151 ic and could represent a synapomorphy for an as-yet undetermined terrestrial clade of Palaeozoic amni

152 nt of TMPRSS2 expression and supported by an as-yet-undetermined protease(s).

153 is independent of TMPRSS2 and carried out by as-yet-undetermined protease(s).

154 lncRNAs), and enhancer RNAs (eRNAs), as well as yet undiscovered classes of transcripts.

155 supports the hypothesis that there are many as yet undiscovered hidden allosteric sites and suggests

156 As yet undiscovered particles and interactions might exi

157 CRY stability implicate the existence of an as yet undiscovered regulatory mechanism.

158 Cryptosporidium might use as-yet undiscovered purine transporters and salvage enzy

159 This linguistic variation is as yet unexplained but could be the result of ecological

160 ph phase abundance in an otolith depends on, as yet, unexplained genetic and environmental factors.

161 This paradox is, as yet, unexplained.

162 f the TH1 type but there are some subtle and as-yet-unexplained differences.

163 nally perturbed during the disease, but with as-yet-unexplained heterogeneity among IBD subtypes and

164 ologue FtsZ and represents an attractive but as yet unexploited target for new antibiotics.

165 This represents an as yet unexploited target to treat bacterial infection a

166 overy and the potential insights provided to as yet unexplored aspects in plant LD functions, our dat

167 verns the biological effects for most GPCRs, as yet unexplored for the IGF-1R, we sought to investiga

168 cally active microstructures, exploiting the as yet unexplored regime of highly confined liquid cryst

169 Cell, 2019) describes an as yet unexplored role for one of the Rab11 binding prot

170 ternal diet for HMO biosynthesis and provide as yet unexplored targets for future studies investigati

171 We propose PDR1 as an as yet unexplored trait to be investigated for crop prod

172 hese immune responses on host physiology are as yet unexplored, and may have long-term implications i

173 bound on individual nanotubes could lead to, as yet unexplored, spontaneous chemical reactions.

174 g lytic reactivation in epithelial cells are as yet unexplored.

175 oexist with the cochlear ones, a possibility as yet unexplored.

176 corporate decision-making has enormous, but as yet unfulfilled, potential to promote sustainable dev

177 0.1 [C6H14OSi](+) to highlight known as well as yet unidentified ascaroside components in TMS-derivat

178 inst type I R-M systems, Ocr associates with as yet unidentified BREX system complexes containing Brx

179 strated that intracellular replication in an as yet unidentified cell type was essential for dissemin

180 dentified phenolic acids, saponins and other as yet unidentified compounds may contribute to the perc

181 distinct other brain regions, suggestive of as yet unidentified coordinate regulation of brain regio

182 were able to identify candidate proteins for as yet unidentified crucial steps in central metabolisms

183 ity of the cytoplasmic domain in response to as yet unidentified environmental signal(s).

184 probands, likely indicating the existence of as yet unidentified genes.

185 ated in the CHH disease phenotype through an as yet unidentified mechanism.

186 tends synthesis following nt insertion by an as yet unidentified Pol.

187 the nucleotide inserted opposite 1-MeA by an as yet unidentified Pol.

188 ormation of aragonite suggesting there is an as yet unidentified process in the living coralline that

189 H-independent and requires HAVCR1 or another as yet unidentified receptor(s) but not NPC1.

190 alamus, exerting an orexigenic effect via an as yet unidentified receptor.

191 Pol DNA synthesis in vitro, suggestive of an as yet unidentified role of PrimPol in mtDNA metabolism.

192 In addition, the presence of the as yet unidentified silicon phase, Si-VIII and two of ou

193 It can be envisaged that specific as yet unidentified small molecules might bind to the F(

194 in transport into the brain involves another as yet unidentified transporter molecule.

195 This result suggests that other, as yet unidentified viral proteins encoded by spliced mR

196 but leave open the possibility that another, as yet unidentified, mechanism of desensitization also e

197 mitochondrion harbors some Tpx and, another, as yet unidentified, oxidoreductase.

198 an transmission, suggesting that additional, as-yet unidentified amino acid mutations are needed for

199 nt evidence suggests the existence of other, as-yet unidentified APCs also able to prime T cells.

200 ges to the wound through the detection of an as-yet unidentified chemoattractant.(3-5) Similar H(2)O(

201 ants suggest the contribution of additional, as-yet unidentified cytokines to intrathymic T cell deve

202 pofuscin may be disease driven, secondary to as-yet unidentified drivers accelerating autophagic path

203 ctivity of a previous sulfur insertion by an as-yet unidentified enzyme.

204 enome-wide nucleotide content, indicating an as-yet unidentified sequence bias for NP association in

205 suggest that while CXCL10 interacts with an as-yet-unidentified component on the cell surface, PDHc

206 Na(+) binding drives the transporter into an as-yet-unidentified conformational state, involving rear

207 sting the possibility of the existence of an as-yet-unidentified DNAM-1 ligand which may be particula

208 periodically enter the cilium, suggesting an as-yet-unidentified mechanism that triggers ciliary entr

209 Ultimately, we show that an as-yet-unidentified nonsecreted cell wall protein is req

210 addition to integrin alphaIIbbeta3, another as-yet-unidentified receptor is thought to mediate plate

211 ng that MC159 prevents IKK activation via an as-yet-unidentified strategy.

212 Additional, as-yet-unidentified substrates are likely to explain the

213 ing that mutations in HCCS, COX7B, and other as-yet-unidentified X-linked gene(s) cause selective los

214 and prevent spread of virus to neighboring, as yet uninfected, cells.

215 ts has suggested the presence of additional, as yet unknown 'don't eat me' signals.

216 e inhibition of maternal growth by seeds, an as yet unknown activity of the hormone.

217 unusual metalloenzymes, as these may install as yet unknown alterations.

218 host, we suggest it could have been from an as yet unknown and possibly ancient host.

219 observed an Ni(2+)-mediated oligomer with an as yet unknown biological function.

220 These results reveal that an as yet unknown cAMP-activated signaling pathway controls

221 were shown to promote IL-17A production with as yet unknown clinical implications.

222 natural history of the disease; 2) discover as yet unknown disease pathways linking diabetes to athe

223 dophytic root microbiomes harbor a wealth of as yet unknown functional traits that, in concert, can p

224 To identify as yet unknown interaction partners of NFAT, we purified

225 in combination with LC-MS/MS, we identified as yet unknown intra- and intermolecular contact sites o

226 points to a residual effect because of many as yet unknown loci that overlap between CAD/MI and CAC.

227 k dedicated stiffness sensors, we rely on an as yet unknown mechanism that generates stiffness percep

228 n in PXE, but there might be an alternative, as yet unknown mechanism, independent of PPi, by which A

229 phagosomes detach from the ER membrane by an as yet unknown mechanism, undergo intracellular transpor

230 okes inhibition of the phospholipase C by an as yet unknown mechanism.

231 f Met compared with control seeds through an as yet unknown mechanism.

232 YS1 might indirectly affect Wag31 through an as yet unknown mechanism.

233 ion during sepsis, causes lung injury via an as yet unknown mechanism.

234 1 broadens virus tropism through a distinct, as yet unknown mechanism.

235 reatic islets (PIs) of beta-cells through an as yet unknown mechanism.

236 with associated furan ring formation, by an as yet unknown mechanism.

237 g cell adhesion molecules, but also by other as yet unknown mechanisms.

238 s most probably occur near nesting colonies, as yet unknown or no longer preserved in the immediate s

239 at Amphionides is a larval form, but with an as yet unknown parentage.

240 oduce and secrete these enzymes points to an as yet unknown physiological function.

241 sensory neurons by using a host of known and as yet unknown protein machinery.

242 diseases, these processes are disrupted for as yet unknown reasons.

243 their universality suggests that they confer as yet unknown selective advantage to DNA.

244 A small molecule natural product of as yet unknown structure, mycofactocin, is thought to be

245 Here, we report evidence of an as yet unknown type of contractile ring-independent cyto

246 ional Ctf18-RFC complex, aid this process in as yet unknown ways.

247 phatic drainage and transport of exosomes is as yet unknown, although the lymphatics play critical ro

248 n multiple targets and each followed unique, as yet unknown, rules governing acceptor-site preference

249 e, in addition to ferredoxin and NADP(H), is as yet unknown.

250 ia, but its association with skin cancers is as yet unknown.

251 ver, its function in cortical development is as yet unknown.

252 owever, the precise molecular mechanisms are as yet unknown.

253 ism by which REST is regulated in neurons is as yet unknown.

254 predisposed individuals with exposure to an as-yet unknown antigen.

255 receptor density, compartmentalization, and as-yet unknown binding partners.

256 minin species other than Homo sapiens, at an as-yet unknown date.

257 of secreted polysaccharides post-Golgi by an as-yet unknown mechanism, and not necessarily by differe

258 otypes contain numerous additional genes for as-yet unknown metabolites.

259 Here, we hypothesize that an as-yet unknown peptide is involved in the action of angi

260 nce learning requires an understanding of an as-yet unknown relationship between flexibility and brai

261 Undaunted by both known and (as yet) unknown challenges, pursuit of myocardial regene

262 the hitherto-known taxa and may represent an as-yet-unknown Acinetobacter species.

263 We suggest that this may represent an as-yet-unknown binding site for a partner protein requir

264 las and gibbons via one or more intermediate as-yet-unknown hosts.

265 drug resistant tuberculosis, representing an as-yet-unknown lineage, named Lineage 8 (L8), seemingly

266 associated with serious adverse effects and as-yet-unknown long-term consequences.

267 Our data indicate that an as-yet-unknown mechanism of antitermination of transcrip

268 ciation of RAS with blood vessel walls by an as-yet-unknown mechanism, ultimately promoting a 7-fold

269 ow, perhaps just signaling, level through an as-yet-unknown mechanism.

270 nce for a common underlying etiology with an as-yet-unknown mechanism.

271 weetness preferences, suggesting that other, as-yet-unknown mechanisms play a role and that these mec

272 n the isolation of other microorganisms with as-yet-unknown molecular biomarkers.

273 s activated to alpha-RP via alpha-R using an as-yet-unknown route to convert DMB to alpha-R and CblS

274 In liver, a signature with an as-yet-unknown underlying mechanism is predominant.

275 ctive cancer vaccines remains an urgent, but as yet unmet, clinical need.

276 es for more advanced disease are urgent and, as yet, unmet clinical needs.

277 toms of antihydrogen to search for possible, as yet unobserved, differences in the physical behaviour

278 xide (.NO) and has been suggested to form an as-yet unobserved bound heme-iron-PN intermediate in the

279 y that duplex opening will terminate and the as-yet-unopened dsDNA portion will bind to another C-ter

280 nses before symptom onset and explaining the as-yet unpredictable outcomes of pathogen exposure.

281 licability for routine disease diagnosis is, as yet, unproven.

282 what to anticipate from the large cohort of as-yet unpublished clinical trials in this arena.

283 also represents a potentially abundant, but as yet unquantified, food source to benthic predators [9

284 ties of domain engineering and potential for as-yet-unrealized nanoscale functional devices.

285 rk matter harbors diverse producer taxa with as yet unrecognized drug discovery potential.

286 This finding has strong and as yet unrecognized implications for many applications o

287 meostasis, and osmotic resistance through an as-yet unrecognized link of HNF1A to sphingolipid homeos

288 hat the combined effect of many thousands of as yet unreported IPF susceptibility variants contribute

289 Eleven as yet unreported mutations in the laminin-332 genes wer

290 presented in some of their skin biopsies an as yet unreported pathological finding in human VCA, con

291 ously thought and include unique lipids with as yet unresolved properties.

292 A critical, and as yet unresolved, question is whether the mucosal bottl

293 ective immunotherapeutic strategies, through as-yet unresolved mechanisms.

294 This study sheds light into the as yet unrevealed action of PFOS on lipid mediators in a

295 neity of cancer has led to a persistent, and as yet unsolved, challenge to develop cures for this dis

296 itiating statin therapy to treat COVID-19 is as yet unsubstantiated by the evidence.

297 s reason, we propose that Ric-8 proteins are as yet untested therapeutic targets in which pharmacolog

298 nfant interactions supported the common, but as yet untested, hypothesis that maternal mirroring of i

299 As yet we have no means to reconstruct the pacing of LIP

300 chanism that leads to organ dysfunction, but as yet we have no therapeutics that can influence this p