ライフサイエンスコーパス: association

1 insights into choosing an appropriate target association.

2 erminus of MEILB2 and preventing MEILB2 self-association.

3 4.9% for both cohorts) having the strongest association.

4 oposed as the microbial link underlying this association.

5 ting causal effects by using genetic variant associations.

6 T1D development, finding null or protective associations.

7 irming known interactions and predicting new associations.

8 ped benchmark containing 42 newly discovered associations.

9 raphic characteristics did not attenuate the association (1.41 [95% CI, 1.14-1.73]), but further adju

10 merican College of Cardiology/American Heart Association 2013 pooled cohort risk equation.

11 prepregnancy adherence to the American Heart Association (AHA) diet recommendations and the Dietary A

12 ting for mental disorders, three significant associations, all on chromosome 20, were identified: rs4

13 The 2018 American Heart Association/American College of Cardiology Multi-Society

14 n by demonstrating the relative strengths of association among subcomponents across a range of cognit

15 mary statistics from the largest genome-wide association analysis of MD (n = 135,458 cases, n = 344,9

16 ique study uses a novel combination of human association analysis, CRISPR genome editing in mice, ani

17 he equilibrium stability of the complex, the association and dissociation kinetics, and the microvisc

18 ted that Y138 is a critical residue for Brd4 association and that inability to complex with Brd4 does

19 architectural dissection reveals the mode of association and topology of the complex, casts light on

20 his enhances the strength of the GRIP1-AMPAR association and, subsequently, the insertion of AMPARs i

21 nal regression to assess the significance of associations and Bonferroni corrected for multiple compa

22 state-of-the-art results on 12 disease-gene associations and on a time-stamped benchmark containing

23 ffectively predict potential circRNA-disease associations and provide highly credible candidates for

24 We confirmed and extended known associations and reported several novel causal associati

25 y of amino acid composition, structure, self-association, and adhesion modality in a panel of variant

26 dimer transition, clear evidence of membrane association, and probable structures of prefusion interm

27 The kinetics of antibody-antigen association are enhanced when charge redistribution is a

28 Many of these associations are unexpected based on efficacy data or ev

29 fetal genetic effects behind these observed associations are unresolved.

30 alue of .01 or less in the same direction of association as in the discovery cohort.

31 dividuals, we identified 5,552 trait-variant associations at p < 5 x 10(-9), including 71 novel assoc

32 istration data from 5 states to estimate the association between a neighborhood socioeconomic depriva

33 After case-mix adjustment the association between a Nursing Activities Score per nurse

34 Previous studies demonstrate an association between activation of the maternal immune sy

35 Our data suggest an association between Alzheimer's disease and NPH changes,

36 adjusted analyses, there was no significant association between baseline eGFR <60 ml/min per 1.73 m(

37 ts fail to confirm the null hypothesis of no association between BCG vaccination and COVID-19 mortali

38 ng a rat model, we investigated the possible association between Blastocystis infection, colonic hype

39 egression models were applied to analyze the association between body height and dementia.

40 The epidemiological bidirectional association between breast cancer and schizophrenia may

41 r's spirituality significantly moderated the association between care partner depressive symptomatolo

42 gical QOL (B=0.03, P<0.05) and moderated the association between care partner depressive symptoms and

43 Background Growing evidence indicates an association between cerebral microhemorrhages (MHs) and

44 The association between chronic inflammatory demyelinating p

45 We do not find any association between CNV burden and cognition.

46 Results showed a significant association between cord serum interleukin-7 at birth an

47 Program (SARP) III cohort, we determined the association between DHEA-sulfate and percentage predicte

48 The authors aimed to assess the association between diastolic dysfunction (DD) and outco

49 There was no significant association between donor MDRO and either measure of org

50 We assessed the association between gender (cisgender or transgender) an

51 The association between HBGA status and G3P[6] rotavirus vac

52 ditional logistic regression to estimate the association between hourly particle metrics and MI cases

53 There was an association between IgG1 titer and SNP rs3901533 of dect

54 The association between incidence of diabetes mellitus (DM)

55 We examined the association between inflammation and NP levels in humans

56 A total of 18.8% of the association between lifetime systolic blood pressure bur

57 There was no association between liver stiffness and any patient vari

58 Here we show a strong association between low circulating plasma serine peptid

59 to which pre-pregnancy obesity mediates the association between maternal place of birth and severe p

60 f pre-pregnancy obesity as a mediator in the association between maternal place of birth and the deve

61 tors accounted for substantially less of the association between MDD-PRS and depression when under st

62 Most studies (n = 30) identified a positive association between payments and prescribing in all anal

63 ent status of target establishment (i.e., an association between pediatric anxiety and a specific neu

64 In addition to a positive association between periodontal disease, dental caries,

65 tudy, we tested the hypothesis of a positive association between plasma ANGPTL5, and obesity, high se

66 25 studies (44.0%) reported a significantly association between preexisting LA-DRVs and risk of viro

67 A negative association between pure tone audiometry and mini-mental

68 s of PSC that exhibit a significant negative association between PZC and CRP or AGP, application of t

69 Regression models were fitted to assess association between residing in food insecure hotspot co

70 We found an association between self-identified black race and progr

71 Impact of the QRSarea/LVEDV ratio on the association between sex and LV reverse remodeling (LV en

72 The observed association between the delta(13) C and WUE(plant) sugge

73 There was no significant association between the duration of mTOR inhibitor thera

74 udies have raised concerns about a potential association between the implementation of HIV PrEP and t

75 We aimed to prospectively characterize the association between the infant/toddler gut microbiome an

76 The association between the number of postoperative complica

77 ck-ins of YAP target genes, we show a strict association between these resets and downstream transcri

78 Moreover, there was no association between unit policies and prolongation of ge

79 ng restricted cubic splines to determine the association between volume and short-term outcomes.

80 We observed positive associations between a fast increase in built-up land us

81 The aim of this study was to evaluate the associations between ADHD polygenic risk scores (PRS) an

82 , population-wide health database to examine associations between antenatal IPT exposure and adverse

83 A plethora of genetic associations between distinct loci and various traits ha

84 Associations between each pattern [treelet component (TC

85 We estimated associations between fruit and vegetable intake relative

86 We retrospectively studied associations between LGE presence and adverse cardiovasc

87 Associations between malpractice risk measures and healt

88 Observational data suggest associations between marijuana and a broad range of adve

89 The present study intended to explore the associations between maternal lipid profile and small-fo

90 veolens L.) as a model herb, we reveal novel associations between metabolite profile and sensory qual

91 and microclimate analyses revealed negative associations between minimum relative humidity, which wa

92 ly for CNS and non-CNS survivors, identified associations between PA consistency and neurocognitive o

93 dies from the last century have drawn strong associations between paternal life experiences and offsp

94 We observed nonlinear associations between PFOA in pregnancy and some measures

95 lore whether DNA methylation changes mediate associations between prenatal PFAS exposures and child h

96 d meta-analysis to quantify the longitudinal associations between reward processing abnormalities and

97 We examined associations between rod- and cone-mediated vision and H

98 The associations between specific DISE findings and FTP were

99 ance populations, the seasonal and genotypic associations between sporadic cases and outbreaks are su

100 There were dose-response associations between steps, SB (inverse) and MVPA quarti

101 C), which relies on the ability to establish associations between stimuli, with the eyelid closure it

102 The aim of our study was to investigate associations between symptoms of gastroenteritis and the

103 This study also found promising associations between thalamic glial histological signatu

104 d linear regression to examine country-level associations between the gender development index and th

105 anked list of papers that contain meaningful associations between the keywords.

106 th Centre between 2008 and 2017, we analyzed associations between the stage of syphilis (primary vs s

107 We analyze heterogeneity in the association by wealth quintiles and age groups and prese

108 ms, and to quantify the extent to which such associations can be attributed to a general factor of ch

109 Nevertheless, target associations can be recovered by incorporating (possibly

110 ular localization, protein function, complex association, cell type of origin, and by the cellular en

111 he relationship between LVEF, New York Heart Association class on presentation, and the end points of

112 when the task was such that ingroup and self associations competed, only the self-advantage was detec

113 the exo-tert-butyl ones, leading to apparent association constants more than one order of magnitude h

114 to our results, and the vast majority of the associations could not have been identified with a genot

115 its properties are derived from a Cubic Plus Association (CPA) equation of state.

116 Overall, 25 CpG sites show consistent association directions for the methylation-gene expressi

117 Federation of Pharmaceutical Industries and Associations (EFPIA).

118 one of four curve shapes: the straight line, association exponential curve, rise-and-fall to zero cur

119 sion regulation through the dynamic AGO2-RNA association for human neuronal development.

120 variables fails to identify the significant association for walleye pollock, and (d) cod and pollock

121 We found similar magnitude inverse associations for estrogen positive (ER(+ve)) breast canc

122 hms characterized by profound changes in the association, from gene expression to behavior.

123 ry heart failure to disabling New York Heart Association functional classes III/IV (5.2%/year); 67% h

124 Collectively, we reveal self-association functions as an additional mode of Gle1 regu

125 self-targeting CRISPR screening and guilt-by-association genomic search strategies.

126 merican College of Cardiology/American Heart Association guideline on the primary prevention of CVD i

127 A strong association has been reported between RA and periodontal

128 However, no robust associations have been observed between neuroanatomical

129 TBC1D15-NuMA1 association impaired asymmetric division machinery by hi

130 We evaluated this association in a prospective birth cohort setting.

131 The UMFA-ASD association in Black children slightly attenuated after

132 We also observe an association in discovery (adjusted OR = 2.61, P = 7.98 x

133 -threatening disease; and transcriptome-wide association in lung tissue revealed that high expression

134 rted here supports the notion that PCSK9-LDL association in the circulation inhibits PCSK9 activity.

135 h, we investigated structural brain-behavior associations in an extensively phenotyped developmental

136 We validated a subset of the observed associations in an independent case-control study of typ

137 further investigate HLHS-cardiomyopathy gene associations in cases versus controls, rare variant burd

138 creasing eczema severity, with the strongest associations in people with severe eczema (compared with

139 cated that the nanohaloarchaeon-haloarchaeon association is both mutualistic and symbiotic; in this c

140 27 plays a significant role in mediating the association kinetics, undergoing conformational rearrang

141 Despite these described associations, many cases of familial WT remain unexplain

142 We also used regional association mapping (RAM) to supplement results from GWA

143 lly associated with SSL risk and part of the association may be due to HCA intake.

144 accounted for all of the inter-generational association (mediation effect: 99%; P value < 0.001).

145 ors identified novel genome-wide significant associations near genes involved with global regulation

146 ations at p < 5 x 10(-9), including 71 novel associations not found in EUR populations.

147 tic models have been proposed to explain the association of AF and dementia.

148 Society of Echocardiography and the European Association of Cardiovascular Imaging guidelines for pre

149 We studied the association of Cd and smoking exposures with human blood

150 ients with peripheral artery disease and the association of changes in symptom classification with su

151 ior" treatment modality as compared with the association of enamel matrix derivative (EMD) with ABG i

152 We found no association of genetically predicted PCOS with risk of d

153 The association of home noninvasive positive pressure ventil

154 approach in yeast cells to measure chromatin association of individual replisome subunits, thereby ch

155 In addition, we suggest how changes in the association of lipid-binding caveolar proteins upon flat

156 We aimed to examine the association of metabolic health status and its transitio

157 We investigated association of microglial markers at time of diagnostic

158 The association of Miltefosine with GM-CSF do not improve th

159 ht/obesity; those findings indicate that the association of muscular fitness with white matter micros

160 We tested the association of rs72613567 with plasma levels of alanine

161 Overall, no association of selenium alone or antioxidants was seen w

162 We examined the association of self-reported race (Black, White, or othe

163 Published evidence suggests a positive association of self-reported TFA intake with non-Hodgkin

164 with diabetes mellitus and quality control, association of single nucleotide polymorphisms (SNPs) wi

165 ts for MR analysis to investigate the causal association of the 25(OH)D metabolites with T2D (includi

166 cooperation of members of the Heart Failure Association of the ESC, the Heart Failure Society of Ame

167 We examined the association of the risk score with plasma markers of liv

168 tization, suggesting mechanisms bridging the association of their genomic loci with IR.

169 of European ancestry do not support a causal association of total 25(OH)D or 25(OH)D metabolites with

170 ation within the high-risk families, and for association of variants with predicted functional impact

171 this study was to assess the prevalence and associations of active trachoma among rural preschool ch

172 In adjusted regression analyses, we examined associations of brain insulin signaling with diabetes, A

173 used mixed-effects linear models to analyze associations of changes in standardized weight, length/h

174 Associations of clinical or radiographic characteristics

175 ack and white young adults, we evaluated the associations of E-selectin and ICAM-1, obtained at year

176 Risk in Communities study, we quantified the associations of eGFR (based on creatinine and cystatin C

177 nic kidney disease in those with gout, novel associations of gout with other comorbidities have been

178 Furthermore, previously reported associations of IgG Fc glycosylation with age in healthy

179 We determined associations of MC1R genetic risk categories and phenoty

180 We aimed to examine associations of milk content of HMOs and bioactive prote

181 However, associations of our UHC indicators with the share of GDP

182 We also found strong associations of PCB congener distributions with Aroclors

183 There was no evidence for associations of physical activity with histologic types

184 the frequency, characteristics, and outcome associations of relative hypoglycemia in diabetic patien

185 Associations of sleep characteristics with mild cognitiv

186 Novel associations of sputum and oral microbiota to immunologi

187 Twenty associations P(FDR) < 0.05 were detected between lipidom

188 524 unrelated TS samples and replicated the association (P value = 0.001).

189 In previous studies, we genotyped an association panel of 508 inbred lines genotyped with a t

190 sociations and reported several novel causal associations providing important insights about the caus

191 tic analyses reveal that these form-function associations reflect convergence towards predictable tra

192 ront the requirement of the Specialty Coffee Association regarding the total absence of Quaker beans

193 nctional variants and key genes within these association regions remains a major challenge.

194 dermatitis (AD), but several aspects of this association remain unclear.

195 Intriguingly, the mechanism underlying this association remained unknown.

196 ther shared risk factors, with a significant association remaining only for ACR (>=103 compared with

197 IQGAP1 associated with cdc42 and R-ras; this association required the GAP-related domain (1004-1237 a

198 Genome-wide CNV breakpoint association showed not only significant loci for genetic

199 prioritizes causal variants underlying GWAS association signals and reports relevant regulatory elem

200 significant (P < 1.28 x 10(-11)) independent association signals for 459 cell traits at 70 loci (53 o

201 e previously reported, we present additional association signals for the traits.

202 lture, in determining this spatial numerical association (SNA).

203 merization at the replication origin but the association state remains unclear.

204 ured geographical confounding on genome-wide association studies (GWAS) of complex human traits in th

205 polygenic risk scores (PRS) from genome-wide association studies (GWASs) including 55,105 CRC-affecte

206 findings from a meta-analysis of genome-wide association studies (meta-GWASs) of the broad depression

207 Genome-wide association studies have revolutionized our understandin

208 In recent years, genome-wide association studies have shed light on the genetics of e

209 Genome-wide association studies have shown many variants are found w

210 Data from genome-wide association studies in up to 215,551 participants from t

211 the 3rd strongest risk locus in genome-wide association studies of Parkinson disease (PD).

212 ic risk score (PRS) derived from genome-wide association studies of posttraumatic stress disorder (PT

213 50 well-curated gene sets and comparison of association studies using Z-scores, modified Z'-scores,

214 to perform cell type-specific methylome-wide association studies within subpopulations of neurons/gli

215 Rationale: GWAS (Genome-Wide Association Studies) have identified hundreds of genetic

216 e used to interpret results from genome-wide association studies, and we discuss current challenges f

217 ed heritability enrichment in 64 genome-wide association studies, emphasizing schizophrenia.

218 ted with type 2 diabetes risk in genome-wide association studies.

219 -analyses with 2 independent EoE genome-wide association studies.

220 rgans with body mass index (BMI) genome-wide association study (GWAS) data from >457,000 individuals.

221 Our genome-wide association study (GWAS) identified one novel genomic ri

222 We performed a genome-wide association study and analysed the most recent Parkinson

223 A genome wide association study demonstrated that both dietary and end

224 We performed a genome-wide association study in Arabidopsis (Arabidopsis thaliana)

225 In addition, we used a genome-wide association study to identify loci that are associated w

226 We utilized sequence kernel association testing and polygenic risk score (PRS) metho

227 Commonly used RV association tests have limited scope to leverage variant

228 amine was used in 34 FVE and 24 CAE, with no association to AV complete visualization rates (p = 0.30

229 hat the mechanism of the initial bimolecular association to form the intermediate state can be mediat

230 Europe and exhibits demographic and cultural associations to the Yamnaya culture.

231 The association varied according to time since diagnosis wit

232 The association varied by histotype, with increased risk of

233 th risk of ASD, although the nature of these associations varies considerably with factors in the per

234 The INSTI-DM association was attenuated (HR=1.03 [0.71-1.49] vs. NNRT

235 ty and DCGF was mediated by BPAR, no similar association was found for DWFG.

236 Among translation components, RNA association was most reduced for initiation factors invo

237 No significant association was noted between VL, admission to intensive

238 No significant association was observed between fundus abnormalities, V

239 A positive association was observed between the absolute interocula

240 This association was replicated in two independent samples of

241 No association was seen between high aFXa and 90-day clinic

242 The TB/DM association was significant at enrollment in both new an

243 as associated with lifetime asthma, and this association was stronger when an electronic vapor produc

244 L1-ankyrin-G association was studied using immunoprecipitation, Weste

245 However, these associations were all attenuated until null by sequentia

246 These associations were attenuated after adjusting for other s

247 No associations were found for any immunological variables

248 ely associated with ICH risk, no significant associations were found for HDL and triglycerides (both

249 All associations were independent of socio-demographics and

250 f clinical AD; especially, the time-specific associations were notable: t-tau 8 to 16 years, and Nf-L

251 These Htt/HTT associations were replicated in the Q175 Htt knock-in mo

252 thin minutes of learning a novel odor-reward association, whereas the pPC lacks an explicit represent

253 t single nucleotide polymorphism (SNP)-trait associations, which leads to high sequencing cost.

254 is an assemblage of microorganisms living in association with a multicellular host.

255 The association with AF was more significant (odds ratio, 6.

256 There was no association with ART initiation in the hospital and rete

257 but not its gelsolin-like domains, mediated association with cdc42, R-ras, and IQGAP1.

258 There was no association with cognition, language or behaviour.

259 identify an increased prevalence of ADHD in association with early life exposure to PFOS and PFOA.

260 djustment for body mass index eliminated the association with endometrial cancer but had limited effe

261 mped' in a sub-compartment created by Scc2's association with engaged heads whose coiled coils are fo

262 lin/Cdk1 activity normally declines in tight association with increasing N/C and is regulated by N/C.

263 al care settings, 15 found no evidence of an association with liability risk and 5 found limited evid

264 g re-initiating) ART in the hospital and its association with linkage to HIV care, frequency of outpa

265 15LO1-PEBP1 and LC3-II are seen in HAECs, in association with low bronchoalveolar lavage fluid mitoch

266 CCA cells was also in regions of ER in close association with mitochondria.

267 eIF4E's association with noncoding RNAs strongly positions it to

268 after injury, which may partly underpin its association with OA risk.

269 e prevalence of Adv36 seropositivity and its association with obesity and diabetes among adults atten

270 For HbA1c, however, the association with obesity duration persisted, independent

271 oderate-certainty evidence showed a probable association with older age; elevated C-reactive protein

272 in versus amoxicillin and in particular, the association with P-gp, a major pathway for clarithromyci

273 f genetically defined renal tumors and their association with patient clinical and genetic characteri

274 In 2007 only the association with physical domain (physical functioning,

275 ument hundreds of rodent coprolites found in association with plant material, and tentatively assign

276 We prioritize RAMS11 due to its association with poor disease-free survival and promotio

277 es should be weighed against its significant association with postoperative underaction of IO muscle

278 Interaction analyses suggested an association with road traffic noise at the least exposed

279 ZA MIC for PZA susceptible strains showed no association with SCC in crude or adjusted analyses (HR 0

280 multiple epidemiology studies supporting its association with T2D.

281 AD), but to the knowledge of the authors the association with tau burden is unknown.

282 KARRIKIN INSENSITIVE2 (KAI2), triggering its association with the E3 ubiquitin ligase complex SCF(MAX

283 s) repress cardiomyocyte hypertrophy through association with the prohypertrophic transcription facto

284 the large ribosomal subunit and prevents its association with the small subunit.

285 is needed to understand the source of these associations with a person's place of residence.

286 hus, miRNA assessment at baseline identifies associations with C-peptide and stratifies subjects for

287 We further determined associations with change in ADHD symptoms.

288 thood for 2 major dietary patterns and their associations with childhood and parental factors.

289 ct drugs in London and to test any potential associations with demographic characteristics, past diag

290 (OR = 2.02 [1.60-2.55]) showed the strongest associations with dysglycemia but none outperformed HbA1

291 Associations with educational attainment attenuated afte

292 h gene expression level as well as prominent associations with histone modifications that typify acti

293 r and logistic regression analyses examining associations with immune parameters and key demographics

294 We evaluated multivariable-adjusted associations with IOP using linear regression and with g

295 The differences in genetic associations with prevalent and incident CAD between men

296 We monitored microbiota maturation and associations with subsequent development of allergies in

297 ge chromatin interactions and mRNA abundance associations with target genes, and were enriched in mot

298 Genetic associations with the risks for developing alcohol-relat

299 of this study was to define the risk of, and associations with, SAE and high-dose radiation exposure

300 The associations within and between individuals in patient-c