ライフサイエンスコーパス: at best

1 that total fishing effort remains constant (at best).

2 rge states and can provide a single electron at best.

3 essential plant hormone is still fragmentary at best.

4 underlying pathologic factors is incomplete at best.

5 d of their role in pathology, is rudimentary at best.

6 ates with resolution limited to 4.3 angstrom at best.

7 antioxidants in human disease has been mixed at best.

8 y modest regioselectivity would be predicted at best.

9 l significance of these reductions is modest at best.

10 se conclusions provide a partial explanation at best.

11 symptomatic therapies provide modest benefit at best.

12 rug-based approaches have been controversial at best.

13 ins of Mycobacterium tuberculosis is minimal at best.

14 l develop a persistent pain syndrome is poor at best.

15 ot be excluded, but it is likely to be small at best.

16 ing fluids with attolitre (10-18 l) accuracy at best.

17 nths and 1-year overall survival (OS) of 35% at best.

18 reatment over traditional therapy is minimal at best.

19 n to blood products is currently conjectural at best.

20 ngly the contribution of such leaps is minor at best.

21 f such an advantage does exist, it is modest at best.

22 e been disappointing, or of unproven benefit at best.

23 of compositional isomers by MS is equivocal at best.

24 eutic results in a few studies are equivocal at best.

25 performed can yield descriptive information at best.

26 sphaethene-isoprene DA reactions are modest, at best.

27 whereas sequential treatments were additive at best.

28 al measures of visual function were moderate at best.

29 h as Parkinson's disease have been equivocal at best.

30 ti-gp41 cluster II MAbs was poor to moderate at best.

31 ts inappropriate and the inference equivocal at best.

32 of potent antiretroviral therapy is partial at best.

33 fection of primary macrophages inefficiently at best.

34 ein and herbimycin A, moreover, was marginal at best.

35 ates such as CO would be expected to be weak at best.

36 gh empirical support for this claim is mixed at best.

37 SERS signal is still limited or disorganized at best.

38 ng reproducibility will yield marginal gains at best.

39 in this study, the associations were modest at best.

40 ions under in situ conditions is rudimentary at best.

41 SDG 3.2 achievement in Africa is precarious at best.

42 tratification/disease prediction speculative at best.

43 cin reflect central release are questionable at best.

44 he evidence base for this conclusion limited at best.

45 evidence supporting this concept is limited at best.

46 ons in patients with heart failure is modest at best.

47 nvolved in GBM recurrence remain rudimentary at best.

48 e primordial genetic material is fragmentary at best.

49 Here, we show that this view is incomplete at best.

50 at true risk, which, at present, is moderate at best.

51 ever, therapeutic PKP provided globe salvage at best.

52 activity of SIRT6 but this effect is modest at best.

53 t-wolf reintroduction are flawed and tenuous at best.

54 atments only give modest symptomatic benefit at best.

55 am lithography have a resolution of a few nm at best.

56 istribution, is only a partial poverty index at best.

57 models rarely forecast beyond a single year at best.

58 c rates of epoxyalkane conjugation that were at best 0.6% of the CoM-dependent rate, while ethanethio

59 ndard gait control parameters achieve speeds at best 2 orders of magnitude smaller than the 2 body le

60 ptor sites have been mutated to alanines was at best 2 to 3% of that of the wild-type P protein.

61 ll generally the fastest available at 1.2 to at best 2.4 times faster than Parasail for sequences sho

62 truments have historically been accurate to, at best, +/-2% of the reduced ion mobility (K(0)) value

63 agree with experiments on polar molecules to at best 25 per cent accuracy and fail to predict binding

64 rvival associated with changing therapy was, at best, 3 to 6 months.

65 nt in a changing world, estimating that 65% (at best 37%, at worst 97%) of native terrestrial taxa an

66 This ratio is at best 5 if alloreactivity is 5%.

67 However, the diagnostic yield achieved is at best 50%, leaving the genetic basis for disease unsol

68 The regression models explained at best 57% of the variation in decline rate in soil and

69 -labeled A-NK cells, it was determined that, at best, 75% of 1 x 10(7) cells delivered i.s., and up t

70 xcept in acute or advanced disease, provides at best a crude guide to net efficacy and safety.

71 olutionary birth-death processes, fitness is at best a derived quantity, and owing to the potential c

72 represented by those observed in only one or at best a few provinces and municipalities.

73 y from p-coumaryl alcohol, a monomer that is at best a minor component in the lignin of other plants.

74 g water treatment, Cl2O is predicted to have at best a minor impact on chlorination reactions, wherea

75 ment and that hematopoietic plasticity plays at best a minor role in adult organ maintenance and rege

76 g events in extracellular Leishmania but has at best a minor role in intracellular pathogenesis.

77 ial parameters, confirming that mI(Kr) plays at best a minor role in repolarization of adult mouse ca

78 protein L33, in contrast to protein L28, has at best a minor role in ribosome assembly and function.

79 at depolarization-mediated Ca2+ influx plays at best a minor role in the transient phase I constricti

80 lated to interfacial tension gradients, play at best a minor role.

81 for attracting retinal fibers, while playing at best a redundant role in the retinal fibers themselve

82 band densitometry) and, thus, have provided at best a semiquantitative assessment of tumor levels.

83 ontrol, countries in sub-Saharan Africa have at best a tenth of the pathology coverage of that in hig

84 ate in the leucine biosynthetic pathway, was at best a very poor substrate for the Tmt1 yeast enzyme.

85 hat the higher intelligence of academics has at best a very weak effect on reducing their bias, facil

86 V replication in HepG2.2.15 cells; there was at best a weak correlation between assembly thermodynami

87 ative brain tumors, and survival benefit is, at best, a few weeks longer than that with procarbazine.

88 bodies against the DIII-lr epitope comprise, at best, a minor component of the human anti-WNV antibod

89 ulations and that the Q62R polymorphism has, at best, a minor effect on diabetes risk.

90 ersal response, but that amacrine cells had, at best, a minor role.

91 erefore, the neuropathological diagnosis is, at best, a probability statement.

92 experimental tests indicate that the FLO is, at best, a slave oscillator to the TTFL, which underlies

93 EnvZ-OmpR signalling whereas osmolarity has, at best, a weak effect on the EnvZ-OmpR system.

94 imates suggest that algal photosynthesis is, at best, able to convert approximately 5-7% of incident

95 At present, treatment at best achieves symptom control rather than cure, and t

96 Tamoxifen demonstrated modest activity at best against endometrial carcinoma and does not warra

97 uch as Bcl-2 should be minimally protective, at best, against purely energetic insults.

98 hat Tyrannosaurus was limited to walking, or at best an 11 m s(-1) top speed, whereas others argue fo

99 usion always leads to coagulopathy and so is at best an adjunct to good surgical care.

100 Therefore, Greenberg's language groups are at best an imperfect approximation to the genetic struct

101 finity or off rate are important, they offer at best an incomplete explanation.

102 ucture corresponds to a transition state or, at best, an extremely shallow minimum.

103 Human endotoxemia is, at best, an incomplete model of human sepsis.

104 only be achieved over micrometre-scale areas at best and defects exist at the edges of grain boundari

105 eatment recommendations in myeloma is modest at best and has an ample scope for improvement.

106 hepatocyte repopulation is a very rare event at best and is not of clinical relevance.

107 laser and conventional therapy is difficult at best and likely impossible at the present.

108 Fluctuations result in dim lights at best and power outages and broken appliances at worst

109 ess genes by gene targeting, are inefficient at best and thus are not routinely used.

110 ng temporal resolution is limited to minutes at best, and correlated factors may not actually be pres

111 algesic drug targets is likely to be modest, at best, and has been largely dismissed in favour of a s

112 the benefit of chemotherapy has been modest at best, and no one combination has shown significant su

113 en-used structure-frequency correlations are at best approximate and at worst misleading.

114 anything more than very modest selectivities at best ( approximately 2:1).

115 Nonetheless, current models explain, at best, approximately 60% of the observed variance, hig

116 Official EE IO data are, however, at best available for single countries or regions such a

117 isorder patients report their services to be at best 'average' and more often 'poor' in quality.

118 v 15, 2014, we expect the interventions will at best avert 53 957 (46 963-60 490) EVD cases.

119 result of such biases, the avidity index may at best be a mere surrogate for undefined antibody or ot

120 using cyclophosphamide/TBI conditioning may at best be effective in only a small fraction of patient

121 clease is weakly phosphorylated in vitro (4% at best) by PKC, cGMP-dependent protein kinase, casein k

122 S-225975 does not cause tumor regression and at best causes partial tumor growth inhibition in staged

123 from hundreds of different organisms and are at best challenging to assemble comparably to single-org

124 evidence supporting their pathogenicity is, at best, circumstantial.

125 We show that, at best, common genetic variation can only have a modest

126 g, weakly neutralizing MAb to the CD4bs was, at best, completely ineffective at protection.

127 properties towards a desired reactivity is, at best, complex.

128 ttention to the appropriate use of terms is, at best, confusing to the student, researcher, and clini

129 n homocysteine-related pathologies is often, at best, conjectural.

130 se results suggest that domain unfolding can at best contribute partially to the 4-fold extensibility

131 itochondrial pathway in any invertebrate is, at best, controversial.

132 This view would explain why immunotherapy at best delays progression of type 1 diabetes mellitus a

133 that Tmods and Lmods are interchangeable or, at best, different variants of two subfamilies of pointe

134 ely, anti-D monoclonal antibodies have been, at best, disappointing.

135 5.3, P < .004), and the mean reading acuity "at best distance" improved from 0.33 logRAD (95% CI: 0.2

136 approaches are limited in resolution and can at best distinguish a twofold (or 50%) difference in cop

137 At best, DNNs can label inputs, while our object percept

138 At best, during persistent virus infection the person mu

139 ar Pattern molecules (DAMPs) suggested that, at best, early application at a sufficiently high dose c

140 e evidence in support of these hypotheses is at best equivocal.

141 ictions, evidence supporting this theory is, at best, equivocal.

142 inical management of vitiligo is challenging at best, even when combining anti-inflammatory and/or im

143 s, while detection on RC bacteria minimally, at best, exceeds background.

144 , and available treatment and management can at best extend survival to a modest degree.

145 urves revealed a loss of half a Snellen line at best focus, with no change for intermediate vergence

146 suggests that the D2-Ala260 peptide nitrogen at best forms a weak hydrogen bond with QA-.

147 Distances were large at best frequencies, in which the formants differ but we

148 e threshold for a 20 ms probe tone presented at best frequency was determined for various masker-prob

149 ated as vector strength in response to tones at best frequency, and by constructing shuffled and cros

150 urvive until donor organs are available and, at best, fully functional replacement organs.

151 centrate on stimulating T cell immunity will at best generate broadly reactive and persisting T cell

152 abinoid and novel compounds and suggest that at best GPR55 is an atypical cannabinoid responder.

153 ge that most of the affected offspring would at best have a severe infantile form of the disease.

154 The former two, at best, have equivocal activity, but testosterone is bo

155 ven well-studied model organisms are sketchy at best, highlighting the continued need for computation

156 At best, however, only a small percentage of sections fr

157 Institutes of Health grant applications are at best imprecise predictors of research projects' scien

158 these risk assessment tools perform modestly at best in discriminating between individual women who w

159 4A) but the sequences are marginally related at best in each pair (average pair-wise sequence identit

160 functional ATPase domain played a minor role at best in facilitating protein accumulation.

161 arib is FDA-approved), but they are additive at best in wild-type cancer cells.

162 atients and can normalise the GH/IGF-I axis (at best) in approximately 65% of individuals; however, t

163 e numbers of people who have no insurance or at best inadequate insurance.

164 dynamics of splenic germinal centers, it is at best incomplete and does not reproduce the distributi

165 from 10x to 15x coverage, the contig length at best increased at a lower rate or even decreased.

166 form of retrospective mortality figures and, at best, indicates an average performance over time.

167 hip between PLIN5 and insulin sensitivity is at best indirect and is apparent only in conjunction wit

168 Such a process may be at best inefficient and at worst potentially harmful.

169 X' is at best initially nearly neutral, but can gain a transmi

170 those notions as either logically flawed or at best insufficient in the absence of natural selection

171 demonstrating that optical-density waves are at best insufficient to explain all motile behavior in m

172 At best, interventions enacted in and around the drinkin

173 areas between the two devices were moderate at best (intraclass correlation coefficients = 0.12-0.65

174 hich normalize individual Hi-C datasets, or, at best, jointly normalize two datasets.

175 ons are often either empirically derived, or at best judged by their ability to elicit broad inflamma

176 ingle putative psychiatric syndrome provides at best limited evidence for the validity of that syndro

177 onists have been developed, yet most exhibit at best limited functional selectivity for a given recep

178 absence of anti-Gag antibodies (which have, at best, limited antiviral activity) is indicative of di

179 e promotor, standard temozolomide (TMZ) has, at best, limited efficacy.

180 However, the resulting tumor killing was, at best, limited.

181 At best, local network alignment attempts to alleviate t

182 CRT delivered at best LV endocardial sites is more effective than via

183 neutral PAHs of small and moderate size can at best make only a minor contribution to these emission

184 ntal to the fidelity of population codes, or at best marginally favorable compared to independent cod

185 er, the native states of these proteins are, at best, marginally stable, with the apparent stability

186 recent studies have highlighted that this is at best minimal compared with the ability of satellite c

187 ry and LP-derived epithelial cells expressed at best minor levels of C3aR.

188 ure is strewn with terminology that has been at best misleading and at worst, a hindrance to selectin

189 Reproducibility of arteriolar lesions was at best moderate (kappa </= 0.62).

190 analyses consistently demonstrating small or at best moderate expectancy effects, and high accuracy i

191 gene duplicability, the effect seems weak or at best moderate.

192 mposite scores for posttransplant outcome is at best moderate.

193 ein and erythrocyte sedimentation rate have, at best, moderate diagnostic and predictive value.

194 drug for the treatment of ALS, Riluzole, has at best, moderate effect on patient survival and quality

195 ver all time scales, yet support values were at best moderately higher.

196 rimental models over the past 30 years, with at best modest disease-modifying effects.

197 s with active disease, this regimen provides at best modest palliation.

198 c aldehydes and alkyl halides proceeded with at best modest selectivity (diastereomeric ratios up to

199 R) inhibitors indicate good tolerability and at best modest to no clinical activity in a variety of h

200 leukin-4-inducible DNA binding activity, but at best modest trans-activation of reporters containing

201 human subjects given supplements of CLA were at best modest.

202 e, the accuracy of hospital report cards is, at best, modest for small to medium-sized case loads (i.

203 l coupling of these substrates proceeded in, at best, modest yield for two of the four examples teste

204 ive responses and clinical benefit that was, at best, modest.

205 s 10 dB above pure-tone spike rate threshold at best modulation frequency are (95% CI) 11.6% (10.0-13

206 However, this target sequence is at best necessary but not sufficient to specify a hotspo

207 st likely to suffer adverse consequences, or at best not benefit.

208 ing fuels from CO2 is a very long-term niche at best, not the panacea suggested in the recent public

209 ms of CGP 35348 at sites in the VMM produced at best only a very modest attenuation of the antinocice

210 Though vaterite is at best only kinetically stable, that stability is tunab

211 have typically been costly, impractical, and at best only minimally successful.

212 which ineffective clinical interventions can at best only mitigate, and at worst temporarily exacerba

213 In conclusion, radiofrequency ablation is at best only modestly effective for managing patients wi

214 eme-deficient neuronal isoform (apo-nNOS) is at best only partially activated.

215 This implies that selection is at best only partly responsible for the property of erro

216 ly and geochemically important organisms are at best only remotely related to any strain that has bee

217 th COS-1 cell extracts, but appeared to have at best only very modest affinity for SF-1.

218 At best, only 17 of 62 nurses (27%) using the 2-componen

219 ansfected cells indicated that they express, at best, only a fifth as many proteins on their surface.

220 reast cancers, and that screening is having, at best, only a small effect on the rate of death from b

221 Systemic osteopenia is, at best, only a weak risk factor for periodontal disease

222 in the watershed, but this effect explained, at best, only approximately 40% of the nitrate decline.

223 to produce normal MuLV on their surfaces, or at best, only at very low levels.

224 RuPZn fragments of these structures exhibit, at best, only modest excited-state electronic interactio

225 Recent advances have yielded, at best, only modest gains.

226 At best, only modest increases in affinity were realized

227 to vitronectin induced by A23187 and AA was, at best, only partially inhibited by nordihydroguaiareti

228 recombinant human IL-2 were ineffective and, at best, only partially reduced tumor load.

229 ent after Katrina are likely to persist and, at best, only partly recover.

230 , the available protocols are time consuming at best or even impossible for some regions in NMR spect

231 blocking the plant xylem, this hypothesis is at best overly simplistic.

232 olecular biology of HIV-1 latency control is at best partially understood, and the literature remains

233 rade, and type of dysplasia remains moderate at best, particularly in light of the recent recognition

234 crorobots cannot actively deform, exhibiting at best passive bending under external fields.

235 s, at zero positive end-expiratory pressure, at best positive end-expiratory pressure identified thro

236 before and after a recruitment maneuver, and at best positive end-expiratory pressure identified thro

237 of the National Psoriasis Foundation arrived at best-practice recommendations through group discussio

238 ed assays could be performed in <30 min and, at best, provided a visual read of 10-100 pfu in a 100-m

239 of emerging symptoms and/or to qualitative, at best quantitative, descriptions of the accumulation o

240 al reactive intermediate is G(-H)(*), which, at best, reacts only slowly with H(2)O and lives for app

241 ead, social media effects are nuanced, small at best, reciprocal over time, gender specific, and cont

242 Resective surgery is at best regarded as a practice option because there is a

243 All but one patient (90%) showed at best response reduced perfusion values in terms of re

244 decreased from 3510 to 1460 mg/dL (P < .001 at best response).

245 At best response, 85% of patients had improvement or res

246 , and a >50% increase from the value reached at best response, had a shorter survival after initiatio

247 At best response, median serum immunoglobulin M declined

248 At best response, the complete response/very good partia

249 At best response, their median serum immunoglobulin M de

250 it increased from 29.8% to 38.2% (P = .0002) at best response.

251 matocrit rose from 33.0% to 37.6% (P = .004) at best response.

252 of activating the low-avidity T cells that, at best, retard the tumor growth.

253 gates the characterization of AKI to remain, at best, retrospective and causally noninformative.

254 on imaging has been primarily qualitative or at best semiquantitative in nature, assessing regional p

255 sult is an assay that is time-consuming and, at best, semiquantitative.

256 At best, separation plates of up to 2.7 x 10(5)/m were o

257 empty capsid was an off-pathway dead end or at best served for storage of pentameric subunits, which

258 DmORC displays at best six-fold differences in the relative affinities

259 chanism of action of many of the enzymes are at best speculative, indicating a need to develop method

260 ng the clinical relevance of Blastocystis is at best speculative.

261 agement of severe acute asthma in adults and at best suggest only a limited role for intravenous MgSO

262 to measure NNS intake yield crude estimates at best, suggesting self-reports are not reflective of a

263 The data at best support only a weak interpretation of the serial

264 Existing treatments are at best symptomatic.

265 symptomatic, centred on decongestive drugs, at best tailored according to the initial haemodynamic s

266 cussed by Pothos & Busemeyer (P&B) establish at best that quantum probability theory (QPT) is a logic

267 Accumulating data suggest that, at best, the hypothesis is incomplete.

268 At best, the immunological activity of 33-mer was reduce

269 At best, the opportunity to capitalise on a discovery ha

270 cal mechanics offering a rough approximation at best, the past three decades have seen an explosion i

271 gical and social interventions suggest that, at best, these can affect social outcomes.

272 At best, these reagents perturb the isoelectric point of

273 At best, this inhibition is described as contributing to

274 However, increasing evidence suggests that, at best, this mechanism can account for only part of the

275 ical 'artifacts' of tissue damage, and were, at best, thought to be minor lipohilic constituents of v

276 t to electric ones, are generally considered at best to be convenient macroscopic parameters, rather

277 ed studies, there is some evidence (level II at best) to support treatment--a grade B recommendation.

278 uman genital infection, although it appears, at best, to be partial.

279 ledge of human neural circuits is difficult, at best, to obtain.

280 uently than every 5 years would likely lead, at best, to only modest improvements as compared with a

281 only limited homologies (25 to 33% identity) at best, to the four previously categorized type I famil

282 nonintensivists whose interests are neutral, at best, to the needs of intensivists.

283 r, its utility in improving outcome remains, at best, uncertain.

284 In addition, one splice acceptor site was at best underutilized.

285 Current data indicate that, at best, vaccine-induced immunity may not completely pre

286 particles and the solid electrode surface is at best very difficult and leads to voltage polarization

287 innervate sympathetic efferents and project at best very lightly to the VRC.

288 s a mixed picture of GIP involvement with an at best weak anorectic response profile being reported f

289 the research evidence for their efficacy is, at best, weak.

290 e that the hole/electron-transfer process is at best weakly activated (12-15 kJ mol(-1)) at room temp

291 Furthermore, social networks are at best weakly scale free, while a handful of technologi

292 The randomized trials suggest that screening at best will have a small survival benefit but substanti

293 e fibers to chemical stimulation were modest at best with an absence of chemical specificity.

294 he treatment of bone pain remains palliative at best with systemic therapy (analgesics, hormones, che

295 that triplet intermediates coordinate weakly at best with the ethyl groups of triethylsilane.

296 ignals achieved by hyperpolarization decays, at best, with a time constant of a few minutes.

297 redominant genotype (genotype 1) is moderate at best, with only about 40% of the patients showing sus

298 redominant genotype (genotype 1) is moderate at best, with only about 40% of the patients showing sus

299 irect comparisons across studies are tenuous at best without data on early iron status and certainty

300 ctive isolation measures in hospital clinics at best would only ensure control with probability 0.87