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1  the demonstration of the leverage principle at first.
2 epeatable EIS measurements were not possible at first.
3                                              At first, 10,184 molecules structurally similar to the k
4 r 31, 2016), or loss to follow-up (censoring at first 12-month interval without a visit if there were
5 ember 2016), or loss to follow-up (censoring at first 12-month interval without a visit with no futur
6                                              At first, 3,515 references related to the topic were ext
7 on occurred (assessed as moderate intensity) at first administration under medical supervision and wa
8 proportional hazards regression to model age at first adult-focused PCP visit and time from the last
9                                              At first, an overview of the most important and widely u
10 al contraceptive use, pregnancy, parity, age at first and last births, age at menopause, hysterectomy
11 sociation between endometrial cancer and age at first and last live birth, age at menopause, and post
12 rmance, declined while selection on the ages at first and last reproduction remained nearly constant,
13 <110> direction, with preferential positions at first and second nearest neighbors for interstitial a
14 (iii) The forest total AGB increases rapidly at first and then decreases slowly on the temporal dimen
15 es of chemical modification, which decreases at first and then increases considerably.
16  signaling kinases and DNA repair were scant at first, and the initial perception was that the import
17 mer worm-like chain model and a yeast genome at first, and then applied it to generate an ensemble of
18  subgroup of patients with no recanalization at first angiography (12.9+/-6.5% therapy versus 18.8+/-
19       We estimate that RDTs in primigravidae at first antenatal visit are substantially more sensitiv
20             Among 2535 patients seronegative at first antibody test, HCV incidence was 2.25/100 perso
21 ror, 3.8%), and 57.0% (standard error, 4.8%) at first appearance of atrophy, 2 years, and 5 years, re
22                              The baseline SP at first applanation (SP-A1) and highest concavity predi
23 s a multistage process in which the protein, at first, assembles into a ring-shaped complex on the ou
24 e B-cell lymphoma; 93% of responses occurred at first assessment (~9 weeks).
25 uited as early as age 12 and were unaffected at first assessment and reassessed years later as AUD (D
26 pants, 931 [45.5%] were women; mean (SD) age at first assessment was 62.56 (14.63) years.
27 om participants with no cognitive impairment at first assessment who were followed up for as long as
28 among black participants (n = 1306; mean age at first assessment, 57 years; 505 [39%] were men; P <.0
29 among white participants (n = 7482; mean age at first assessment, 59 years; 3373 [45%] were men; P <.
30 e primary outcomes were success rates of NGI at first attempt, success rates of NGI in accumulative a
31                            The mean (SD) age at first AUD registration was 39 (13.4) years.
32                                              At first available follow-up [mean 8.2 (+/- 4.3) years],
33 ary outcome was depressive symptoms measured at first available follow-up, expressed on the Beck's De
34 epressed initial MD (P < 0.01) and older age at first available VF (P < 0.01).
35 of its spatial confinement, this process may at first be undetectable even by nearby LFP electrodes.
36 ts with proteinuria >/=0.5 g/d were enrolled at first biopsy for primary nephrotic syndrome and follo
37                             Mean age (+/-SD) at first biopsy was 48.3 +/- 9.3 years, 59.3% of patient
38 benign breast biopsy, and nulliparity or age at first birth (>/=30 years vs <30 years).
39 hitecture of human reproductive behavior-age at first birth (AFB) and number of children ever born (N
40 ductive and behavioral traits, including age at first birth (variants in or near ESR1 and RBM6-SEMA3F
41 imilarly, variants associated with later age at first birth are associated with a longer maternal lif
42 er and were greater for women who were older at first birth or who had more births.
43                               Parity and age at first birth were combined into a single measure of re
44 We estimated the associations of parity, age at first birth, age at menarche, and menopausal status w
45 che, height, a combination of parity and age at first birth, body mass index at age 18 years, family
46 or each subtype by the exposures parity, age at first birth, breastfeeding, menarche, hormone replace
47 significant associations between parity, age at first birth, breastfeeding, oral contraceptive use, o
48  were similar for race, age at menarche, age at first birth, family history, alcohol consumption, and
49 luding lifetime reproductive success and age at first birth, in either males or females.
50 associated with age at menarche, parity, age at first birth, infertility, use of diethylstilbestrol b
51 or established CHD risk factors, younger age at first birth, number of still births, number of miscar
52 age at menarche, menstrual irregularity, age at first birth, stillbirths, miscarriages, infertility >
53 and 2016 were classified on the basis of age at first birth: 10-19 years (adolescence), 20-24 years (
54                                   Median age at first booking was 25 years (interquartile range [IQR]
55 starch suspension with citric acid decreased at first both the flow index and consistency coefficient
56                                          Age at first breast cancer is a strong risk factor for cumul
57                                              At first, BST-2 genes were described only in humans and
58 onger, with the competence signal decreasing at first but increasing as the infection became septic.
59           Denser wood loses mass more slowly at first but more quickly with advancing decay, which re
60 Young birds followed more exploratory routes at first, but gradually shortened and defined them as th
61 le, while others develop relatively normally at first, but later exhibit impaired endosperm prolifera
62 onalizing mutations rose to higher frequency at first, but more frequent deleterious mutations underm
63                                          Age at first calving (AFC) plays an important role in the ec
64                 In recent years, patient age at first cataract surgery and the age-standardized surge
65  lifetime parity (p = 0.03), and earlier age at first child (p = 0.02).
66 associated with fewer children and older age at first child whereas higher polygenic risk of ADHD is
67 levels, earlier age at menarche, earlier age at first child, higher lifetime parity, lower PCOS risk,
68 me-day ART with a dolutegravir-based regimen at first clinic visit.
69 UNIX) and T2-weighted whole-body muscle MRI, at first clinical presentation and 4 months later.
70  ART initiation on the day of HIV testing or at first clinical visit, regardless of CD4 count.
71                  The mean (SD) full-scale IQ at first cognitive assessment was lower in patients who
72 ed participants (mean age 55.9 +/- 5.7 years at first cognitive assessment, 70% female) were recruite
73 089) at discharge from the maternity ward or at first contact with the health center.
74                                              At-first contradictory electronic structural data are ex
75 ical images taken before starting sorafenib, at first control, after starting sorafenib, at the time
76 formed in a fluid environment they could not at first control, with homeostatic mechanisms developing
77                                              At first CPET, the median peak heart rate was 80% (IQR,
78 venously every 3 weeks (8 mg/kg loading dose at first cycle, and 6 mg/kg thereafter) for 18 doses or
79 6-2011), programmed DDD, had HRSc calculated at first data upload after implant (median 1.4 months).
80         Time-to-event analyses were censored at first date of new cancer event, last contact date, or
81 nd gestational age (based on gestational age at first day of treatment with eligible controls survivi
82 e in 3586 women with epilepsy; mean (SD) age at first delivery of the epilepsy cohort was 30.54 (5.18
83            Patients of any age were eligible at first designation of relapse or progression, or first
84 istributions of the prevalences of infection at first detection in both hosts and vectors.
85 ents, 76 % had PCR cycle threshold (Ct) > 30 at first detection.
86 favorable than unfavorable or advanced stage at first diagnosis (15-year cumulative incidence, 5.3% v
87   Diagnosis<18 years, histological cirrhosis at first diagnosis and SLA/LP antibodies are major risk
88      We identified elevated serum IgG levels at first diagnosis as an independent risk factor for red
89                                      The age at first diagnosis is typically lower for men, compared
90 ical records of 65 patients >50 years of age at first diagnosis of IIH were reviewed based on the Mod
91             The mean (SD) age of individuals at first diagnosis of OCD was 23.4 (6.5) years.
92 , diabetes, hyperlipidemia, and hypertension at first diagnosis of severe obesity were each independe
93                                         Ages at first diagnosis were reported using standard descript
94    We assessed PRS(313) interaction with age at first diagnosis, family history, morphology, ER statu
95                 Apart from their younger age at first diagnosis, there was no significant difference
96 1945-1965-had advanced fibrosis or cirrhosis at first diagnosis.
97 scrotum and should be confirmed or ruled out at first diagnostic step.
98                                              At first diagnostic work-up, 18 patients (64.3%) met the
99 d with a psychoactive substance use disorder at first discharge (cumulative incidence 49.4% [48.4-50.
100                            The effect of age at first dose on the immunogenicity of a 2-dose pediatri
101 or GWs, according to vaccination status, age at first dose, and calendar time.
102 .4%) withdrew due to subjective side-effects at first dose.
103 gative (GMC <150 mIU/mL) were derived by age at first dose.
104                                   Median age at first dried blood spot test was 2.1 (IQR 1.8-2.5) mon
105   Cu(2+) complexation by the grafted GGH was at first electrochemically evidenced, using cyclic and s
106                                     Mean age at first eligible lens surgery was 4.2 years; 337 (34%)
107 atory viral testing, and other clinical data at first encounter for the URI through day 14.
108                                We find that, at first encounter, MHC I H-2K(b) considers a wide range
109 mediate, forceful response to pathogens even at first encounter, while sparing host cells in the proc
110 en responders and non-responders are present at first episode of psychosis, consistent with dopaminer
111 elapses, including 17 (17%) of 100 diagnosed at first episode.
112  Clinical High Risk for Psychosis (CHR-P) or at first-episode psychosis (FEP) are often treated with
113  on the ALS Functional Rating Scale-Revised, at first evaluation (r = -0.14818; P = .004), and with p
114                    Of them, 457 (25.7%) were at first evaluation [403 by skin tests (ST), 12 by posit
115  the focal leakage group (63 patients), both at first evaluation and at final visit, more PDT-treated
116 he diffuse leakage group (93 patients), both at first evaluation and at final visit, more PDT-treated
117 in family members was determined by symptoms at first evaluation and mutations.
118 tases, treatment line, and tumor progression at first evaluation by computed tomography scan (hazard
119                                     Symptoms at first evaluation correlated with disease expression.
120                                              At first evaluation, 93% of patients were in New York He
121  did not fulfill diagnostic criteria for HCM at first evaluation.
122       There was no effect of genotype on age at first event, P-SCAD, or recurrence.
123 he association with SCAD risk, including age at first event, pregnancy-associated SCAD (P-SCAD), and
124    Fifty-nine patients had tissue genotyping at first evidence of SCLC.
125 e (GA) of 25 weeks, and mean PMA of 33 weeks at first examination met study criteria.
126 age, 14.5 years +/- 7.8 [standard deviation] at first examination).
127 t necessarily require that observation begin at first exposure are discussed.
128 onclusion When prevalent cases of meningioma at first exposure to CT of the head are excluded, no sta
129 tal of 274 anaphylaxis cases were identified at first exposure, with an additional 170 incident anaph
130 ) examined had eye abnormalities (median age at first eye examination, 31 days; range, 0-305 days).
131 opulation-based cohort study in Germany (age at first follow-up 50-80 years, mean follow-up 5.2 years
132 ences between the groups in the rate of AAPs at first follow-up and at the final examination were sta
133                                              At first follow-up RHC (n=763), New York Heart Associati
134 ssociated with death or lung transplantation at first follow-up RHC after initial PAH treatment.
135 to assess variables obtained at baseline and at first follow-up RHC.
136 transient deterioration followed by recovery at first follow-up, and local network deterioration to p
137 defined as a modified Rankin Scale of 0 to 3 at first follow-up.
138 gnificant predictor for the presence of AAPs at first follow-up.
139 d, when available, modified RECIST (mRECIST) at first follow-up.
140               Surprisingly, cuticular ridges at first form normally in the cus2 mutant, but are lost
141         Of the 1471 children, the median age at first FS was 21 months (interquartile range [IQR], 14
142                       These filaments, which at first glance might appear simple, are also surprising
143  rapidity of (1)TT formation in TIPS-BT1' is at first glance surprising.
144 na include functional pairs of neurons that, at first glance, appear to have symmetrically similar re
145                                              At first glance, decayed SDARs did not significantly dif
146                                        Thus, at first glance, GlpF appears to not be optimized for it
147                                              At first glance, the diversity of polyamine structures i
148                                              At first glance, the trailing tentacles of a jellyfish a
149                                              At first glance, these symptoms are difficult to ascribe
150 sions even in situations that do not appear, at first glance, to depend on memory at all.
151                                              At first, gray-scale and color Doppler ultrasonographic
152                                              At first H5N1 target hybrids with padlock probe (PLP) an
153 th the use of an arteriovenous fistula (AVF) at first hemodialysis.
154 candidate predictors of treatment resistance at first hospital contact with a schizophrenia diagnosis
155                                              At first hospitalization, a long duration of untreated p
156 r HIV type 1 RNA viral load, and higher CD4% at first HPV4 vaccination, as well as shorter duration b
157 d between the two study groups regarding age at first IAC injection, disease grouping at diagnosis, p
158                      Location of ROP nasally at first imaging is a significant predictor for subseque
159  The detailed working principle was analyzed at first, in which the nanoscale triboelectrification ca
160  encouraged to visit the study health centre at first indication of any illness.
161 anti-VEGF agent according to the patient age at first injection ($78 323.19-$292 449.87) and frequenc
162 ions based on the agent modeled, patient age at first injection, frequency of injections, and clinica
163 ated by injury severity, recurrence, and age at first injury (ages 0-4, 5-9, 6-10, 15-19, and 20-24 y
164                                              At first interphase, apposed pronuclei align obliquely t
165                   The median gestational age at first IPTp-SP dose was 22 weeks.
166 ime, among children with CHD, the median age at first LDIR procedure decreased from 5.0 years to 9.6
167                                              At first-level care hospitals, pneumonia and meningitis
168  constitute 23 of the 28 procedures provided at first-level hospitals, expansion of access requires t
169                     All procedures performed at first-level referral hospitals in Ghana in 2014 were
170 e births, and positively associated with age at first live birth (all nominal P < 0.05).
171                                              At first look, cell division and neurite formation seem
172 notypic expression in reaction norms for age at first maturity, longevity, fecundity, and maximum siz
173              Negative effects of earlier age at first measles vaccine dose persisted after the second
174 vels were higher in cases (46.3+/-38.6 ng/mL at first measurement and 38.6+/-36.5 ng/mL at second mea
175 e associated with high intracranial pressure at first measurement and over 24 hours (area under the r
176      Methods Patients with stage III disease at first melanoma diagnosis (initial; n = 2,042), or who
177                            The impact of age at first melanoma was observed only in those younger tha
178 modification by age at ALS diagnosis and age at first mention of diabetes in the hospital registers.
179                                              At first meta-memory is defined to express the neuron or
180                                   Median age at first mexiletine dose was 24.3 years (IQR, 14-32.4).
181 e-sex-predicted METs and heart rate recovery at first minute post exercise) were recorded.
182 P-8 total amounts were significantly reduced at first month after treatment (P < 0.05).
183 gmentation in the chromatographic dimension, at first multivariate curve resolution alternating least
184                                              At first, naphthalene is transformed into 4-carboxy-inda
185                        We calculated the age at first neoplasm diagnosis (systematically ascertained
186                                              At first occurrence of tumoral (18)F-FET uptake, TBRmax
187 remained when the groups were matched by age at first OCD diagnosis and after various sensitivity ana
188 rained biologists tend to consistently focus at first on the fast-acting direction, and overlook the
189 nts who have an efficiently-wired connectome at first onset of psychosis show a better subsequent res
190 ers of differentiation between the disorders at first onset.
191                                      The age at first operation (P = .94), the number of angle operat
192 nts with PI3K pathway-activated glioblastoma at first or second recurrence.
193 em cell transplantation should be considered at first or second relapse.
194 g screening meet diagnostic criteria for HCM at first or subsequent evaluations, with the majority pr
195 mino acids or peptides, anthocyanin degraded at first-order reaction rate.
196  stent retriever (SR) or a direct aspiration at first pass technique at 7 U.S. centers between June 2
197 s achieved faster with the direct aspiration at first pass technique than in SR.
198 tion of the dimethylaminovinyl group located at first position, which accelerates the reaction with n
199 ected menses), as was mean gestational weeks at first positive pregnancy test (4 weeks).
200                        Conversely, early age at first pregnancy and nulliparity were significantly as
201                                    Mean time at first pregnancy testing was identical in both arms (2
202 oductive factors (number of live births, age at first pregnancy, and total reproductive duration [tim
203 tive effect of pregnancy is dependent on age at first pregnancy, with young mothers receiving the mos
204 OCT), and OCT angiography (OCT-A) were noted at first presentation and during the study period.
205 rowth indicator tube, and by WGS on isolates at first presentation and in the case of re-presentation
206 quently moderate/severe aortic regurgitation at first presentation compared with women, whereas women
207 digital air-leak monitoring, and pleurodesis at first presentation might lead to an increase in their
208 raphic, clinical, and echocardiographic data at first presentation of 1992 patients with BAV (71.5% m
209                       We studied 15 children at first presentation of AD and after 6 weeks of standar
210 tudy period, patient age and multi-morbidity at first presentation of heart failure increased (mean a
211                              The average age at first presentation was 37 years.
212                                              At first presentation with elevated BP, gestational hype
213 2 to 2014, the socioeconomic gradient in age at first presentation with heart failure widened.
214 ients with anaphylaxis who were normotensive at first presentation, 40 patients experienced hypotensi
215 cirrhosis was already present in 62 patients at first presentation.
216 t least 'possible' bvFTD diagnostic criteria at first presentation.
217 en all patients with first-episode psychosis at first presentation.
218 otemporal dementia (FTD) spectrum disorders, at first presentation.
219  first episode psychosis were using cannabis at first presentation.
220 ighs, the so-called "artificial hashish" and at first presented itself radiologically as interstitial
221                                   Median age at first procedure decreased from 3.4 years (5th and 95t
222 umab, followed by the addition of irinotecan at first progression (arm A) versus upfront use of fluor
223 survival than lomustine alone among patients at first progression of glioblastoma.
224 hat generates collagen-rich scarring that is at first protective but if inappropriately sustained can
225           The most common treatment interval at first reactivation was 8 weeks.
226 reatment (OR range, 1.40-1.50), and severity at first recorded MDD episode (OR range: moderate, 1.61-
227                                      Methods At first recurrence after chemoradiation, bevacizumab-na
228 luded 26 614 visits for 6196 males; mean age at first registry visit was 17.7 years; and median was 1
229  treatment in patients with multiple myeloma at first relapse after a first ASCT.
230         Liso-cel is under further evaluation at first relapse in large B-cell lymphomas and as a trea
231                       Patients were eligible at first relapse or first designation of refractory dise
232 t analyzing risk factors for CNS involvement at first relapse or progression, as well as the outcome
233 egree of advantage as seen with salvage ASCT at first relapse.
234 ations found in a metastatic lesion isolated at first relapse.
235 survivals calculated from day 1 of treatment at first relapse.
236 s to investigate (a) the extent to which age at first renal replacement therapy, achievement of devel
237 on of the variances in longevity (5.9%), age at first reproduction (3.7%) and lifetime reproduction (
238 of variance in the ratio of fertility to age at first reproduction (F/alpha) and lifetime reproductiv
239 longevity, lifetime reproductive output, age at first reproduction and in the proportion of the life
240              Selection for smaller body size at first reproduction can also play a role in their esta
241 d state variables (growth rate, size and age at first reproduction, age-dependent reproductive rates,
242 orse PFS ( P < .001) and progressive disease at first restaging ( P < .001).
243  -2.6 ng/mL [95% CI, -6.6 to 1.4], P = .30); at first restaging, 32.0 ng/mL vs 18.7 ng/mL (difference
244 ), overall survival (OS), and disease status at first restaging.
245 s from 141 women at baseline, at week 4, and at first restaging.
246 rmed survival analysis investigating the age at first SCD in carriers of the mutation.
247 enia diagnosis (1.54 [1.35-1.75]), inpatient at first schizophrenia diagnosis (2.07 [1.87-2.29]), par
248                       The model included age at first seizure, baseline seizure classification, histo
249 e determined the association between the age at first severe respiratory syncytial virus (RSV) diseas
250  vaccination (18.7 years) was older than age at first sex (15.7 years).
251 38 loci associated (P < 5 x 10(-8)) with age at first sexual intercourse.
252  selectivity, which could have been thought, at first sight, as the exclusive domain of chemical fact
253      Surprising as these results might occur at first sight, they can be understood with the help of
254                        It was my second love at first sight-that of my wife preceded it.
255 continuous expansion since 25,000 years ago, at first slowly from about 7,300 to 9,800 (at the end of
256                      Though counterintuitive at first, SR has been demonstrated in a variety of natur
257                                       TIMPSI at first study visit was associated with risk of combine
258                                   Median age at first surgery for trisomy 13 was 92 (IQR, 30.5-384.5)
259 sal defect margin had evidence of recurrence at first surveillance colonoscopy (10/192, 5.2%) than co
260 comes were complete resection and recurrence at first surveillance colonoscopy in a per polyp analysi
261 argin significantly reduced polyp recurrence at first surveillance colonoscopy, compared with no addi
262  endpoint was detection of lesion recurrence at first surveillance colonoscopy.
263                                   Median age at first symptom was 12 years.
264                                          Age at first syncope of at least 35 years was associated wit
265                                          Age at first TC diagnosis and treatment intensity influenced
266 e age >= 30 years (2.8%; 95% CI, 2.3 to 3.4) at first TC diagnosis than those age < 30 years (6.0%; 9
267 and progesterone receptor status, or by ages at first-term birth or diagnosis.
268                                              At first, the rate constants of chlorine, bromine and mo
269                                              At first, the synthesis of propargylic amines via the Cu
270 fully human antibody which is routinely used at first therapy for metastatic melanoma.
271                                      Indeed, at first thought one might consider the effect to breach
272  5.04 million Finnish individuals, we looked at first-time inpatient admissions in Finland for a diag
273     Graft loss was associated with older age at first transplant (p = 0.008).
274                                          Age at first transplantation was 47.2 (14.9-67.0) years.
275                                          Age at first trauma could help explain discrepancies in resu
276                                     Mean age at first treatment was 79.7 years (standard deviation =
277 ing periods, increasing age of investigators at first U.S. National Institutes of Health R01 grant, a
278 .5] years), 92121 (96.7%) provided their age at first use and 93156 (97.8%) provided the reason.
279 s assessed the accuracy of self-reported age at first use of optical correction and incremental impro
280 ation, self-report of the reason for and age at first use of optical correction are accurate in ident
281                         Duration of use, age at first use, and recency of use did not modify these as
282 ernal antibody concentrations and infant age at first vaccination both influence infant vaccine respo
283  healthy children aged 6 months to <10 years at first vaccination with influenza-like illness (ILI) w
284      In phase a, children aged 12-22 months (at first vaccination) from Czech Republic (Czechia), Gre
285  7,280 vaccinated infants (5-17 weeks of age at first vaccine dose) from 22 trials and 33 countries/t
286  regression was used to examine whether gait at first visit could predict time to PD conversion after
287 and questionably decreased autofluorescence) at first visit was 2.6 (2.8) mm2.
288                     Baseline characteristics at first visit were used as predictors of trajectory gro
289    An estimated 50% of the eyes without DDAF at first visit will develop the lesion in less than 5 ye
290 in Tanzania, combining testing and treatment at first visit with IPTp-SP may offer benefit, especiall
291                                              At first visit, all patients had a detailed ophthalmic a
292 % (83/196) had a CD4 count </= 350 cells/mul at first visit, of whom 92.8% initiated ART within 3 mo.
293                                              At first visit, overall mean QOL scores were below the U
294                      Among eyes without DDAF at first visit, the median time to develop a DDAF lesion
295 sting glucose (IFG; i.e., 100-125 mg/dL FBG) at first visit.
296      A palliative care referral should occur at first visit.
297                                              At first we indicated that yolkin displayed a potential
298                                              At first, we evaluate the influence of all the dynamic a
299                                              At first, we have designed a kit combining the novel flu
300  (age range, 3-50 years) and a mean (SD) age at first wheelchair use of 26 (9) years (age range, 11-6

 
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