ライフサイエンスコーパス: atopic dermatitis

1 Working Party Criteria for the Definition of Atopic Dermatitis).

2 indications were proposed (eg food allergy, atopic dermatitis).

3 oducts is associated with reduced asthma and atopic dermatitis.

4 endent published datasets from subjects with atopic dermatitis.

5 d itch-evoked scratching in a mouse model of atopic dermatitis.

6 bute to lesion formation and intense itch in atopic dermatitis.

7 the eczema area and severity index (EASI) in atopic dermatitis.

8 codynamics in adults with moderate to severe atopic dermatitis.

9 cerns, and long-term effect in children with atopic dermatitis.

10 cells that enter the skin and cause itch in atopic dermatitis.

11 and management of asthma, food allergy, and atopic dermatitis.

12 in levels are downregulated in patients with atopic dermatitis.

13 issue infection to occur in association with atopic dermatitis.

14 lly deleterious effects of PAR2 in models of atopic dermatitis.

15 es several models of itch, inflammation, and atopic dermatitis.

16 tokine frequently associated with asthma and atopic dermatitis.

17 fect on treatment adherence of TCS phobia in atopic dermatitis.

18 n = 825; 79.5%), defined as children with no atopic dermatitis.

19 acitinib in patients with moderate to severe atopic dermatitis.

20 es such as chronic sinusitis with polyps and atopic dermatitis.

21 us disorders, including acne, psoriasis, and atopic dermatitis.

22 uce the risk of allergic diseases, including atopic dermatitis.

23 pectively, when compared to children without atopic dermatitis.

24 ses including asthma, allergic rhinitis, and atopic dermatitis.

25 hat present similar characteristics, such as atopic dermatitis.

26 olescents and adults with moderate-to-severe atopic dermatitis.

27 esults identify new strategies for targeting atopic dermatitis.

28 tential approach for antipruritic therapy in atopic dermatitis.

29 eosinophilic esophagitis, food allergy, and atopic dermatitis.

30 rategy for future prevention or treatment of atopic dermatitis.

31 nflammation such as psoriasis and contact or atopic dermatitis.

32 very) showed no evidence of association with atopic dermatitis.

33 e system development and subsequent risk for atopic dermatitis.

34 olescents and adults with moderate-to-severe atopic dermatitis.

35 EH was associated with atopic dermatitis (11.72 [9.48-14.49]).

36 ether LEKTI exonic mutations associated with atopic dermatitis (AD) affect the protease inhibitory ac

37 Atopic dermatitis (AD) affects up to 20% of children and

38 Atopic dermatitis (AD) affects up to 20% of children wor

39 d/or milk allergy, and/or moderate to severe atopic dermatitis (AD) and a positive egg/milk skin pric

40 nce indicates a relevant association between atopic dermatitis (AD) and attention-deficit/hyperactivi

41 CD8(+) and activated T-cell subsets in AA vs atopic dermatitis (AD) and control blood.

42 Atopic dermatitis (AD) and food allergy (FA) are associa

43 involved in the pathophysiology of not only atopic dermatitis (AD) and psoriasis (PSO) but also lupu

44 Our current understanding of atopic dermatitis (AD) and psoriasis pathophysiology is

45 Disease flares of established atopic dermatitis (AD) are generally associated with a l

46 Molecular studies in atopic dermatitis (AD) are largely restricted to patient

47 n in normal skin and skin form patients with atopic dermatitis (AD) are unknown.

48 ownership and participants were examined for atopic dermatitis (AD) at enrolment.

49 cells (LC) in the epidermis of patients with atopic dermatitis (AD) carry the high-affinity receptor

50 Moderate-to-severe atopic dermatitis (AD) has been associated with signific

51 cia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, th

52 oved for the treatment of moderate to severe atopic dermatitis (AD) in adults.

53 plored racial/ethnic differences in incident atopic dermatitis (AD) in childhood, few studies have ex

54 Farm exposures may reduce the risk of atopic dermatitis (AD) in children, but this is controve

55 Spontaneous development of atopic dermatitis (AD) in NC/Nga (NC) mice has been attr

56 ether 11beta-HSD1 affects the development of atopic dermatitis (AD) in vitro and in vivo.

57 Atopic dermatitis (AD) is a chronic inflammatory skin di

58 Atopic dermatitis (AD) is a chronic inflammatory skin di

59 Atopic dermatitis (AD) is a chronic relapsing skin disea

60 Atopic dermatitis (AD) is a chronic skin inflammation th

61 Atopic dermatitis (AD) is a common chronic inflammatory

62 Atopic dermatitis (AD) is a common chronic inflammatory

63 Atopic dermatitis (AD) is a common illness of childhood.

64 Atopic dermatitis (AD) is a common inflammatory skin con

65 Atopic dermatitis (AD) is a common inflammatory skin dis

66 Atopic dermatitis (AD) is a common skin disease affectin

67 Atopic dermatitis (AD) is a common, chronic inflammatory

68 Atopic dermatitis (AD) is a common, chronic, inflammator

69 Atopic dermatitis (AD) is a common, complex, and highly

70 Recent research advancements indicate that atopic dermatitis (AD) is a complex disease characterize

71 Atopic dermatitis (AD) is a complex inflammatory disorde

72 Atopic dermatitis (AD) is a highly heterogeneous disease

73 Atopic dermatitis (AD) is a highly prevalent chronic inf

74 Atopic dermatitis (AD) is a highly prevalent, itchy infl

75 Atopic dermatitis (AD) is a highly pruritic chronic infl

76 Atopic dermatitis (AD) is a paradigmatic chronic inflamm

77 Atopic dermatitis (AD) is a prevalent disease with varia

78 Atopic dermatitis (AD) is a prevalent disease worldwide

79 Atopic dermatitis (AD) is a prevalent inflammatory skin

80 Atopic dermatitis (AD) is a severe inflammatory skin dis

81 Atopic Dermatitis (AD) is a T cell-mediated chronic skin

82 Atopic dermatitis (AD) is a T helper (Th)2-biased diseas

83 Atopic dermatitis (AD) is among the most common chronic

84 Population studies suggest that atopic dermatitis (AD) is associated with an increased r

85 Atopic dermatitis (AD) is associated with epidermal barr

86 Atopic dermatitis (AD) is characterized by a skin barrie

87 Atopic dermatitis (AD) is characterized by intense pruri

88 Atopic dermatitis (AD) is more common among African Amer

89 Atopic dermatitis (AD) is the most common chronic inflam

90 Atopic dermatitis (AD) is the most common inflammatory s

91 itive factor attachment protein receptors in atopic dermatitis (AD) is unknown.

92 s have assessed molecular changes in chronic atopic dermatitis (AD) lesions, little is known about th

93 between skin sites in diseased skin, such as atopic dermatitis (AD) lesions.

94 of asthma, allergic rhinitis, or both after atopic dermatitis (AD) onset.

95 IL-13 has an important role in atopic dermatitis (AD) pathogenesis.

96 the IL-31 receptor alpha subunit involved in atopic dermatitis (AD) pathogenesis.

97 Atopic dermatitis (AD) patients are often colonized with

98 The fundamental defect(s) that drives atopic dermatitis (AD) remains controversial.

99 nt and tissue homeostasis, but their role in atopic dermatitis (AD) remains unknown.

100 Skin transcriptome studies in atopic dermatitis (AD) showed broad dysregulation as wel

101 Atopic dermatitis (AD) shows differential clinical prese

102 , our therapeutic armamentarium for treating atopic dermatitis (AD) was still primarily topical corti

103 ll function in skin lesions of patients with atopic dermatitis (AD) were recently reported.

104 The genetic background of Atopic Dermatitis (AD) with chronic pruritus is complex.

105 The nonlesional skin of children with atopic dermatitis (AD) with peanut allergy (PA) is assoc

106 member 3A, KIF3A, have been associated with atopic dermatitis (AD), a chronic inflammatory skin diso

107 e (6-11 years) for the assessment of current atopic dermatitis (AD), allergic rhinitis (AR), asthma a

108 ald Leung, who is best known for his work in atopic dermatitis (AD), along with many other contributi

109 ined in adults and young children with early atopic dermatitis (AD), but chronologic changes in the b

110 ces in health care utilization for pediatric atopic dermatitis (AD), but do not account for disease s

111 tablished risk factor for the development of atopic dermatitis (AD), but several aspects of this asso

112 ially a pathogenic cytokine in patients with atopic dermatitis (AD), but the molecular effects of IL-

113 Atopic dermatitis (AD), characterized by pruritis and cu

114 eral chronic inflammatory conditions such as atopic dermatitis (AD), chronic obstructive pulmonary di

115 evaluate the effect of cheese consumption on atopic dermatitis (AD), food allergy (FA), allergic rhin

116 Atopic dermatitis (AD), the most common chronic inflamma

117 al practice guideline "systemic treatment of atopic dermatitis (AD)," we critically appraised evidenc

118 bacteria found on the skin of patients with atopic dermatitis (AD).

119 n in keratinocytes (KCs) in association with atopic dermatitis (AD).

120 role in T cell-mediated diseases, including atopic dermatitis (AD).

121 underlying epithelial barrier dysfunction in atopic dermatitis (AD).

122 the signs and symptoms of moderate to severe atopic dermatitis (AD).

123 -of-life assessments are not standardized in atopic dermatitis (AD).

124 for the subsequent onset and progression of atopic dermatitis (AD).

125 ibitor for the treatment of mild-to-moderate atopic dermatitis (AD).

126 s) are recommended as adjunctive therapy for atopic dermatitis (AD).

127 ts for inflammatory skin diseases, including atopic dermatitis (AD).

128 e occurrence of diseases, such as asthma and atopic dermatitis (AD).

129 coccus aureus is associated with severity of atopic dermatitis (AD).

130 e major predisposing genetic risk factor for atopic dermatitis (AD).

131 area is associated with an increased risk of atopic dermatitis (AD).

132 netic defects in FLG strongly associate with atopic dermatitis (AD).

133 nodularis presents as one of the symptoms of atopic Dermatitis (AD).

134 have revealed multiple loci associated with atopic dermatitis (AD).

135 zed to play a role in the pathophysiology of atopic dermatitis (AD).

136 of care for uncontrolled moderate-to-severe atopic dermatitis (AD).

137 ted a matched case-control study on incident atopic dermatitis (AD).

138 s with psoriasis (n = 30), and patients with atopic dermatitis (AD; n = 16).

139 in patients with inflammatory skin diseases (atopic dermatitis [AD] and alopecia areata [AA]).

140 P < .001; 25.2% vs 15.1%, P < .001; asthma, atopic dermatitis [AD] and rhinitis, respectively).

141 ce or absence of common allergic conditions (atopic dermatitis [AD], IgE-mediated food allergy [IgE-F

142 Atopic eczema (atopic dermatitis, AD) is characterized by disrupted ski

143 Skin biopsies promote our understanding of atopic dermatitis/AD pathomechanisms in infants/toddlers

144 ch on miRNAs in allergic diseases, including atopic dermatitis, allergic rhinitis, and asthma.

145 ood allergen and aeroallergen sensitization, atopic dermatitis, allergic rhinitis, asthma, and challe

146 osition to be associated with development of atopic dermatitis, allergic sensitization, and asthma.

147 ted efficacy for patients with psoriasis and atopic dermatitis, although the biologic target and mech

148 ticoid (e.g., Dexamethasone) an induced skin atopic dermatitis, an induced psoriasis-like inflammatio

149 Atopic dermatitis and allergic sensitization had signifi

150 also a positive additive interaction between atopic dermatitis and allergic sensitization in their ef

151 ety in CRSwNP and other type 2 diseases (eg, atopic dermatitis and asthma).

152 flammation, and has been approved for use in atopic dermatitis and asthma.

153 Atopic dermatitis and bronchial asthma are common diseas

154 atypical findings are noted in management of atopic dermatitis and bronchial asthma.

155 ylococcus aureus (S. aureus) is increased in atopic dermatitis and can result in increased severity o

156 of these genes constitute a risk factor for atopic dermatitis and eczema-related asthma.

157 areata to vitiligo to lupus erythematosus to atopic dermatitis and food allergy.

158 vivo studies, fresh blood from patients with atopic dermatitis and healthy control subjects was analy

159 AD CHRONOS), adults with moderate-to-severe atopic dermatitis and inadequate response to topical cor

160 enefits as a disease-modifying treatment for atopic dermatitis and itch.

161 We find that atopic dermatitis and psoriasis can be classified by dis

162 n chronic inflammatory skin diseases such as atopic dermatitis and psoriasis.

163 d promote inflammatory skin diseases such as atopic dermatitis and psoriasis.

164 (H)2-dominated skin inflammation that mimics atopic dermatitis and sensitizes the airways for antigen

165 in the stratum corneum (SC) of patients with atopic dermatitis and their impaired skin barrier and wa

166 Patients with atopic dermatitis and those with more severe disease had

167 and reduction of lesions in a mouse model of atopic dermatitis and to elucidate possible HOCl's mode

168 ange of skin diseases, including ichthyosis, atopic dermatitis, and a multitude of clinical eczema va

169 ine cutaneous diseases (including psoriasis, atopic dermatitis, and alopecia areata) and eight other

170 mune cells drive diseases such as psoriasis, atopic dermatitis, and alopecia.

171 east with food allergies, allergic rhinitis, atopic dermatitis, and asthma.

172 res and is approved for treatment of asthma, atopic dermatitis, and chronic sinusitis with nasal poly

173 ejection following transplants, treatment of atopic dermatitis, and dry eye disease.

174 cytes from diseases as diverse as psoriasis, atopic dermatitis, and erythrokeratodermia variabilis, s

175 e of the microbiome in patients with asthma, atopic dermatitis, and food allergy.

176 Dermatology clinical trials in psoriasis, atopic dermatitis, and hidradenitis have been suspended,

177 ene drug that is used to treat psoriasis and atopic dermatitis, and is thought to function through re

178 lergy, with a particular focus on asthma and atopic dermatitis, and provide insights into the roles o

179 understanding about sleep, itch, scratching, atopic dermatitis, and psoriasis.

180 Itch, inflammation, and atopic dermatitis are associated with activation of PAR2

181 Allergic skin diseases, such as atopic dermatitis, are clinically characterized by sever

182 uch as asthma, rhinitis, food allergies, and atopic dermatitis, are generally classified by the tissu

183 llergies, including asthma, food allergy and atopic dermatitis, are increasing in prevalence, particu

184 ides a deep insight into the pathogenesis of atopic dermatitis as a ceramide-deficient disease.

185 predictors for adult allergic rhinitis were atopic dermatitis, asthma and asymptomatic sensitization

186 nt risk factor for allergic diseases such as atopic dermatitis, asthma, allergic rhinitis, food aller

187 allergic and inflammatory disorders, such as atopic dermatitis, asthma, rheumatoid arthritis, colitis

188 disease history: He has been suffering from atopic dermatitis, bronchial asthma, and food allergies

189 These polymorphisms associate with atopic dermatitis but how they affect Ca2+ signalling an

190 tes to skin inflammation in diseases such as atopic dermatitis, but the signaling pathways involved a

191 tigate the association between C-section and atopic dermatitis by age four and examine potential sour

192 Caesarean delivery was not associated with atopic dermatitis by age four in this large US cohort.

193 Canine atopic dermatitis (cAD) is a common hereditary clinical

194 a major cofactor in atopic diseases such as atopic dermatitis, chronic rhinosinusitis with nasal pol

195 on biologicals for the treatment of asthma, atopic dermatitis, chronic rhinosinusitis with nasal pol

196 as alopecia areata, vitiligo, psoriasis and atopic dermatitis, common variants have been identified

197 Atopic dermatitis comorbidities extend well beyond the m

198 ensitization is ~50% higher in children with atopic dermatitis compared to children from a high-risk

199 ed through 3 years of age for development of atopic dermatitis; data on allergic sensitization and as

200 Atopic dermatitis, defined as an itchy rash on typical l

201 wever, a specific description of subtypes of atopic dermatitis depending on the timing of onset and p

202 ng prediction tasks from ulcerative colitis, atopic dermatitis, diabetes, to many cancer subtypes for

203 EGPA) in a young girl being treated for both atopic dermatitis, diagnosed at 1 year of age, and bronc

204 ($/QALY) for each moisturizer in preventing atopic dermatitis during a 6-month time window.

205 mab was approved for use in the treatment of atopic dermatitis (eczema).

206 es not increase the risk of food allergy and atopic dermatitis/eczema but may prevent peanut and egg

207 nsumed, and the development of food allergy, atopic dermatitis/eczema, asthma, and allergic rhinitis?

208 ins and the risk of developing food allergy, atopic dermatitis/eczema, or childhood asthma.

209 EAACI Guidelines on the use of dupilumab in atopic dermatitis follow the GRADE approach in formulati

210 ties the incidence of allergic diseases like atopic dermatitis, food allergies, and asthma has risen

211 en the link between skin barrier impairment, atopic dermatitis, food allergy, allergic asthma, and al

212 t new results obtained by uploading a recent atopic dermatitis GWAS meta-analysis to examine the gene

213 inhalant- and food-allergic sensitization or atopic dermatitis had higher circulating memory Treg cel

214 ion with common FLG mutations, children with atopic dermatitis had significantly higher urinary level

215 pies for some chronic itch disorders such as atopic dermatitis has given widespread recognition to th

216 allergic rhinitis, asthma, food allergy, and atopic dermatitis has increased dramatically during the

217 ment of reliable biomarkers in psoriasis and atopic dermatitis has lagged behind therapeutic progress

218 Research into the pathogenesis of atopic dermatitis has led to the testing and development

219 inflammatory diseases, including asthma and atopic dermatitis, has established the need for effectiv

220 and mucosal inflammatory disorders, such as atopic dermatitis, have been associated with an impaired

221 ead to relief of itch in human patients with atopic dermatitis; however, the specific antipruritic me

222 In atopic dermatitis, IL-19 was significantly elevated, cor

223 Atopic dermatitis imposes a significant burden on patien

224 tolerated in adults with moderate-to-severe atopic dermatitis in a phase 2b trial.

225 ulation-based estimates on the prevalence of atopic dermatitis in adults vary widely.

226 ) never versus ever being fed human milk and atopic dermatitis in childhood or 2) the duration of any

227 human milk feeding and allergic rhinitis and atopic dermatitis in childhood.

228 it to PASTURE data separated 4 phenotypes of atopic dermatitis in childhood: 2 early phenotypes with

229 Atopic dermatitis in infancy comprises three immunologic

230 bservations suggest that S. aureus may cause atopic dermatitis in some individuals.

231 is study were to determine the prevalence of atopic dermatitis in the population of the United States

232 conservative estimate of the annual costs of atopic dermatitis in the United States is $5.297 billion

233 ms the high prevalence and disease burden of atopic dermatitis in this population.

234 Information on atopic dermatitis, inhalant- and food-allergic sensitiza

235 thout the individual diseases, children with atopic dermatitis, inhalant-, and food-allergic sensitiz

236 ts (aged >=12 years) with moderate-to-severe atopic dermatitis (Investigator Global Assessment score

237 Atopic dermatitis is a chronic inflammatory skin disease

238 Atopic dermatitis is a common inflammatory skin disorder

239 Atopic dermatitis is a complex, chronic inflammatory ski

240 Atopic Dermatitis is an inflammatory skin disease associ

241 Atopic dermatitis is associated with increased risk of m

242 Atopic dermatitis is dominated by a single microbe (Stap

243 ce on food allergies, allergic rhinitis, and atopic dermatitis is limited.

244 pic Dermatitis, the Patient-Oriented Scoring Atopic Dermatitis-itch, the Patient-Oriented Scoring Ato

245 (RA) on wild-type mouse skin induces a human atopic dermatitis-like phenotype that is triggered by an

246 eks before food allergen sensitization on an atopic dermatitis-like skin lesion, followed by intragas

247 tokines in patients with DOCK8 deficiency vs atopic dermatitis likely reflects disease-specific pertu

248 The use of dupilumab on atopic dermatitis may lead to less risk of infection of

249 ratching and inflammatory responses in mouse atopic dermatitis models.

250 reatment of patients with moderate-to-severe atopic dermatitis (msAD).

251 120 patients with CP of inflammatory origin (atopic dermatitis), neuropathic origin (brachioradial pr

252 ing in the management of eczema (also called atopic dermatitis or atopic eczema) is poorly understood

253 of S. aureus infection, including those with atopic dermatitis or cancer.

254 f cutaneous gene expression in patients with atopic dermatitis or psoriasis.

255 sessed in 137 patients with chronic itch and atopic dermatitis or psoriasis.

256 st have assessed TCS phobia in patients with atopic dermatitis or their caregivers.

257 ading to allergic skin inflammation, such as atopic dermatitis or urticaria, are poorly defined.

258 levels were associated with risk of asthma, atopic dermatitis, or elevated serum IgE levels, using M

259 disease (hay fever: OR: 5.50 [3.42-9.00] and atopic dermatitis: OR 3.76 [2.14-6.61]), and drug use (L

260 timate the association between C-section and atopic dermatitis overall and when stratified by demogra

261 e also measured IL-19 in baricitinib-treated atopic dermatitis patients.

262 e-activity assessment tool for psoriasis and atopic dermatitis patients.

263 tis-related biomarkers in moderate to severe atopic dermatitis patients.

264 were used to analyze the association between atopic dermatitis phenotypes and other allergic diseases

265 that high vitiligo, high psoriasis, and low atopic dermatitis polygenic risk scores (PRSs) were asso

266 ing healthy skin and diseased skin including atopic dermatitis, psoriasis, and acne, among others.

267 be altered in various dermatoses, including atopic dermatitis, psoriasis, and rosacea.

268 APR40 showed modest efficacy and decreased atopic dermatitis-related biomarkers in moderate to seve

269 A biopsy substudy evaluated atopic dermatitis-related biomarkers.

270 eported, but confirmation of their link with atopic dermatitis requires longitudinal studies.

271 there was evidence that C-section increased atopic dermatitis risk among certain subgroups (eg first

272 a positive association between C-section and atopic dermatitis [RR(95%CI): 1.06(1.03, 1.10)], this ef

273 tem Severity Score, and Six Signs, Six Areas Atopic Dermatitis Scale).

274 ermatitis-itch, the Patient-Oriented Scoring Atopic Dermatitis-sleep, and the Numerical Rating Scale

275 TMEM79 is a predisposition gene for Atopic dermatitis, suggesting deregulation of Wnt/FZD si

276 d a stratified approach to the management of atopic dermatitis, supporting the use of targeted treatm

277 lonal antibody (dupilumab) on two cases with atopic dermatitis that was refractory to conventional ma

278 ng neutrophils are key initiators of itch in atopic dermatitis, the most prevalent chronic itch disor

279 Eczema Measure, the Patient-Oriented Scoring Atopic Dermatitis, the Patient-Oriented Scoring Atopic D

280 ibutes to shift the ceramide profile from an atopic dermatitis to a healthy skin phenotype.

281 S], distinctly representing a switch from an atopic dermatitis to a healthy skin phenotype.

282 between primary and secondary prevention of atopic dermatitis to achieve the desired outcome.

283 33, and IL-25 may drive the progression from atopic dermatitis to asthma and food allergy.

284 en with AD, the Mechanisms of Progression of Atopic Dermatitis to Asthma in Children (MPAACH).

285 the prevalence (95% confidence interval) of atopic dermatitis was 7.3% (5.9-8.8).

286 were associated with anxiety and depression, atopic dermatitis was associated with suicidal ideation,

287 Clinical atopic dermatitis was diagnosed in 466/2,052 (22.7%) chi

288 on medical diagnosis of asthma, rhinitis and atopic dermatitis was retrieved for each participant.

289 ess the patient-level and societal burden of atopic dermatitis, we comprehensively reviewed the liter

290 Emollient use and atopic dermatitis were associated with modestly increase

291 Using latent class analysis, 4 phenotypes of atopic dermatitis were identified depending on the onset

292 ples from patients with DOCK8 deficiency and atopic dermatitis were profiled on a cytokine/chemokine

293 in skin biopsies from patients and mice with atopic dermatitis, whereas their inhibition attenuated s

294 IL-22 levels are increased in patients with atopic dermatitis, which commonly precedes asthma in the

295 , and recurrent infections resembling severe atopic dermatitis, while clinically relevant specific Ig

296 6.5 million adults would have a diagnosis of atopic dermatitis, with 6.6 million meeting criteria for

297 Atopic dermatitis without allergic sensitization was not

298 Atopic dermatitis without concomitant allergic sensitiza

299 the skin barrier and prevention or treating atopic dermatitis would have beneficial effects on preve

300 factor in treatment failure in patients with atopic dermatitis, yet it has been sparsely described in