ライフサイエンスコーパス: autacoid

1 c effect of the AT1-ant via kinins and other autacoids.

2 ramide, and other newly discovered bioactive autacoids.

3 ts moderation of pancreas retinol and of the autacoid 9cRA.

4 are largely mediated by the antiinflammatory autacoid adenosine independently of inhibition of prosta

5 adenosine as an endogenous anti-inflammatory autacoid after shock and trauma.

6 d by noninjurious histamine-leukotriene-type autacoids also respond through prompt mucosal exudation

7 nule-derived mediators and newly synthesized autacoids and cytokines.

8 4S,21R-diHDHA acts as a macrophage-generated autacoid, and its attenuated formation in macrophages of

9 LOX), which generates antiinflammatory lipid autacoids, and heme-oxygenase (HO), which generates anti

10 ic acid, a member of the acidic phospholipid autacoid (APA) family of lipid mediators, elicits divers

11 ega-3 or omega-6 PUFA on IRI and renal lipid autacoid circuits, using an established mouse model and

12 All-trans-retinoic acid (atRA), an autacoid derived from retinol (vitamin A), regulates ene

13 These autacoids, derived from omega-6 and omega-3 polyunsatura

14 ion of the AHPslow by a number of endogenous autacoids (e.g., histamine, serotonin, prostanoids, and

15 f upstream signalling pathways, activated by autacoid factors, converge on this crucial target and th

16 We also define A2bR/A2aR-mediated autacoid feedback inhibition of proinflammatory/profibro

17 mega-6 PUFA dramatically impacts renal lipid autacoid formation and outcome of IRI.

18 d-derived neuroprotectin D1 (NPD1) are lipid autacoids formed by 12/15-lipoxygenase (LOX) pathways th

19 diabetes-specific changes in vitreous lipid autacoids including arachidonate and docosahexanoate-der

20 Palmitoylethanolamide (PEA) is an autacoid local injury antagonist distinguished for its n

21 A SF in response to TNF-alpha and acts in an autacoid manner to engage FPRL-1, activate Erk, Jnk, and

22 olvins, a family of specialized proresolving autacoid mediators, eliminated micrometastases in multip

23 d by antiinflammatory and proresolving lipid autacoids, namely resolvin D1 (RvD1), RvD2, or RvE1.

24 ded that the inhibitory effects of these two autacoids on pancreatic beta cell function are not relat

25 ese findings suggest that neurotransmitters, autacoids, or hormones acting on Gq-protein-coupled rece

26 Protein and lipid autacoid profiles were determined by protein arrays and

27 on is now held to be an active process where autacoids promote homeostasis.

28 Adenosine is an autacoid released by all cells.

29 ed within the lumen of vessels suggest a key autacoid role.

30 high 9-cis-retinoic acid (9cRA), a pancreas autacoid that attenuates glucose-stimulated insulin secr

31 ic acid (14,15-EET) is a powerful endogenous autacoid that has been ascribed an impressive array of p

32 production of prostaglandin PGE2, a secreted autacoid that maintains renal function.

33 converts retinol into retinoic acid (RA), an autacoid that regulates energy balance and reduces adipo

34 Adenosine is an autacoid that regulates renal Na(+) transport.

35 The lipoxins (LX) are autacoids that act within a local inflammatory milieu to

36 olving lipid mediators (SPMs) are endogenous autacoids that actively promote resolution of inflammati

37 otectins, and maresins are potent endogenous autacoids that actively resolve inflammation, protect or

38 be clearly defined, but they likely include autacoids that control leukocyte activation.

39 s are enzymatically converted into bioactive autacoids that have inflammation-resolving properties.

40 b) spontaneous release of NO that acts as an autacoid to attenuate the production of the COX-2 produc

41 ssium channels (KCa) and endothelium-derived autacoids to CVD.

42 wave' of Ca2+ along the endothelium releases autacoids to promote pharmacomechanical relaxation.

43 cal levels of adenosine, an antiinflammatory autacoid which inhibits neutrophil function through A2 r

44 e data establish 9cRA as a pancreas-specific autacoid with multiple mechanisms of action and provide

45 However, cellular sources for these autacoids within the vessel wall remain unclear.