ライフサイエンスコーパス: autoactivate

1 ion of kallikrein; factor XII alone does not autoactivate.

2 he propeptide domain controls its ability to autoactivate.

3 ata show that tethered PTH/PTH receptors can autoactivate.

4 ically inactive soluble hepsin was unable to autoactivate.

5 expressed in Escherichia coli, purified, and autoactivated.

6 alyses demonstrated that the cpxRA operon is autoactivated.

7 , except that constitutively active ARF6 was autoactivating.

8 ntramolecular regulation presently known are autoactivating.

9 The ability to autoactivate and then subsequently repress allows for a

10 lysosomal environment because the zymogen is autoactivated and remains optimally active in acidic con

11 C1r both autoactivates and subsequently cleaves and activates C1s

12 cognition protein that binds to bacteria and autoactivates and triggers the prophenoloxidase activati

13 sor (pro-HP14) interacts with peptidoglycan, autoactivates, and initiates the proteinase cascade.

14 lytic cleavage of both the transducer, which autoactivates, and the repressor, which is inactivated,

15 rulence gene expression is controlled by the autoactivated AraC family transcriptional regulator, Agg

16 The K162M mutant did not autoactivate as predicted, however, which may be due to

17 tivation, whereas the Asp(22) --> Ala mutant autoactivated at a 66-fold increased rate.

18 ere identical; however, at pH 5.0, Ile-21-Tg autoactivated at an enhanced rate relative to Asn-21-Tg.

19 eatitis (N29I, N29T, V39A, R122C, and R122H) autoactivated at increased rates and reached markedly hi

20 The structure of autoactivated BAK BH3-BAK complex reveals the conformati

21 Many protein kinases autoactivate by autophosphorylating specific sites at th

22 e marRAB operon is autorepressed by MarR and autoactivated by MarA at a site that also can be activat

23 tron 1 that is activated by activin and Vg1, autoactivated by Xnrs, and suppressed by ventral inducer

24 o p38alpha, is exceptional and spontaneously autoactivates by autophosphorylation.

25 Factor XII (FXII) autoactivates by contact with a variety of artificial or

26 The Ct beta(2) protein also autoactivates by reaction of its reduced (Mn(II)/Fe(II))

27 intervention were tested: inhibition of the autoactivated calcium-dependent kinase (calmodulin kinas

28 Intracellular infusion of autoactivated CaMKII via patch pipette enhanced chloride

29 activates the glnA promoter, this creates an autoactivated circuit repressible by LacI.

30 The caspase autoactivating compound PAC-1 induces cancer cell apopto

31 mammalian development, making its ability to autoactivate critical to its function.

32 (rho), and that sog functions by blocking an autoactivating Dpp feedback loop.

33 tion of apoptosis and differentiation by the autoactivating enediyne, enediyne-5, and the non-enediyn

34 ry glands of transgenic mice that express an autoactivating form of MMP-3/stromelysin-1 under the con

35 Expression of an autoactivating form of MMP-9 in macrophages in vitro gre

36 An allele-specific interaction between an autoactivating form of Snake (Snk) and a gd allele alter

37 Unexpectedly, at a systems level, autoactivated Fus3 appears to have a negative regulatory

38 Addition of autoactivated HP14 elevated phenoloxidase activity level

39 al control over the production of snc1-1 (an autoactivated immune receptor) in Arabidopsis thaliana a

40 luble form of hepsin revealed its ability to autoactivate in a concentration-dependent manner.

41 ssistance of another protease and is able to autoactivate in acidic pH in vitro via a unimolecular me

42 Nercc1 exists as a homooligomer and can autoactivate in vitro by autophosphorylation.

43 Herein we show that purified BACE2 can be autoactivated in vitro.

44 sexta: hemolymph proteinase 14 (HP14), which autoactivates in the presence of microbial surface compo

45 The Nercc1 protein kinase autoactivates in vitro and is activated in vivo during m

46 nzymatically dephosphorylated purified Rad53 autoactivates in vitro through a phosphorylation-depende

47 omain propagates the death signal through an autoactivating interaction with the trigger site of inac

48 a-secretase or is itself gamma-secretase, an autoactivated intramembranous aspartyl protease.

49 MASP-3, which does not autoactivate, is also cleaved by MASP-1 quite efficientl

50 In primary T cells, c-Myb allows GATA-3 to autoactivate its own expression, an event that requires

51 Here, we report that BMI1 autoactivates its own promoter via an E-box present in i

52 ranscriptional fusion, we observed that QseB autoactivates its own transcription.

53 ory zinc ions, thus allowing procaspase-3 to autoactivate itself to caspase-3.

54 This shows that autoactivating kinases have adopted different molecular

55 that prostate carcinoma cells LNCaP and PC3 autoactivate latent full-length PDGF D into its active f

56 Until now the autoactivating mannose-binding lectin-associated serine

57 ERK7 is an ancient and autoactivating member of the mitogen-activated kinase (M

58 However, it is unclear whether the autoactivating modules found within developmental gene r

59 We previously showed that targeting of an autoactivating mutant of the matrix metalloproteinase st

60 covery of several previously uncharacterized autoactivating mutations.

61 (plasma kallikrein) or its unique ability to autoactivate on bacterial or other biologic surfaces.

62 th the mitophagy receptor optineurin (OPTN), autoactivate, or catalyze phosphorylation.

63 mulate expression of endogenous ORF50 and to autoactivate ORF50 promoter reporters.

64 nd GadX activate P3, P2 and P3P2, while GadE autoactivates P1 and represses P3 and P3P2.

65 other Gram-positive bacteria, agr encodes an autoactivating peptide (AIP) that is the inducing ligand

66 alleles under both constitutive (PrpsL) and autoactivated (Pmga4) promoters illustrated that an argi

67 cancer cells, where it displayed an enhanced autoactivating process and a distinct intracellular rout

68 These data suggest that matriptase, an autoactivating protease, acts upstream from prostasin to

69 espite being required for the function of an autoactivated RNL, SADR1 is not required for defense sig

70 Using this system, we defined an autoactivating role for Etv2 that is mediated by two adj

71 ximal to the CaM-binding site leading to the autoactivated state of CaMKII.

72 ionally normal cells expressing an inducible autoactivating stromelysin-1 (SL-1) transgene.

73 1 transgenic animals with mice expressing an autoactivating stromelysin-1 transgene targeted to mamma

74 alveolar epithelial cells of mice expressing autoactivating stromelysin-1 underwent unscheduled apopt

75 nt mutation in the semidwarf Rht-B13b allele autoactivates the NB-LRR gene and causes a height reduct

76 We determined the crystal structure of autoactivated ThnT to 1.8A through X-ray crystallography

77 relief of this inhibition, SnRK2 kinases can autoactivate through unknown mechanisms.

78 ndicated that this receptor was sufficiently autoactivated to produce at least partial differentiatio

79 The yeast Candida glabrata rapidly autoactivates transcription of the AMT1 gene in response

80 We show that, although MASP-2 is able to autoactivate under artificial conditions, MASP-1 dramati

81 Its proenzyme autoactivates under acidic conditions in vitro, resultin

82 activation by upstream kinases, p38alpha can autoactivate when interacting with transforming growth f

83 ses, MASP-1 and MASP-2, have been thought to autoactivate when MBL/ficolin.MASP complexes bind to pat

84 nstrate that endothelial FOXF1 enhancers are autoactivated, whereas mesenchymal FOXF1 enhancers are r

85 proDelta(260-508)MMP-19 has the tendency to autoactivate, whereby the Lys(97)-Tyr(98) peptide bond i