ライフサイエンスコーパス: autograft

1 transplantation in CR1 (25 MRD, 5 MUD, and 6 autografts).

2 e needed to assess the natural course of the autograft.

3 CAR and NAC before implantation of the renal autograft.

4 rization after grafting than split-thickness autograft.

5 remain alive in CR 5, 7, and 15 months after autograft.

6 cine valves, aortic homograft, and pulmonary autograft.

7 rocedure to accommodate the larger pulmonary autograft.

8 f the pulmonary valve preclude its use as an autograft.

9 d the potential growth and durability of the autograft.

10 usion of autoaggressive lymphocytes with the autograft.

11 kness and decreased G. ratio compared to the autograft.

12 gament reconstruction surgery with hamstring autograft.

13 mary closure, or resection with conjunctival autograft.

14 e clonogenic myeloma cell populations in the autograft.

15 ed to soft tissue surgery plus either LCC or autograft.

16 mit their outcomes compared with native skin autografts.

17 lapse risk than patients who received purged autografts.

18 compared with patients who received unpurged autografts.

19 for CSS was less than for conventional skin autografts.

20 tly greater than for conventional 4:1 meshed autografts.

21 These parameters remained unchanged in autografts.

22 th patients grafted with conventional meshed autografts.

23 d the inferior mesenteric arteries served as autografts.

24 ed to recipients of non-T-cell-depleted PBSC autografts.

25 th or without cultured autologous epithelial autografts.

26 y include problematic allografts and limited autografts.

27 stological damage was apparent 3 weeks after autografting.

28 iable tissues, allowing successful immediate autografting.

29 iable subeschar tissues precluded successful autografting.

30 ants of the success of high-dose therapy and autografting.

31 ull-thickness skin defects for 1 week before autografting.

32 the previous group (homografts 1.5+/-0.3 cm, autografts 1.4+/-0.2 cm).

33 A minority of autografts (2 [20%]) were subsequently fully functional,

34 ere randomized to receive either a pulmonary autograft (24 patients aged 40+/-11 years) or an aortic

35 84 (11%) had 4 glands removed with immediate autograft, 40/84 (47%) 3 to 3.5 glands, whereas 35/84 (4

36 ar in both groups (homografts, 5.0+/-0.9 cm; autografts, 5.2+/-0.6 cm; P=NS), and no patient in eithe

37 Cells retrieved from thymic autografts 60 days after implantation exhibited the same

38 ained in both groups (homografts 67+/-15 mL, autografts 67+/-16 mL; P=NS).

39 ches that match or exceed the performance of autografts across critically sized nerve gaps.

40 ogene was developed and used to purge marrow autografts administered to allograft-ineligible chronic

41 also has been used in place of conjunctival autografting after pterygium excision and to reconstruct

42 insulin clearance in two recipients of islet autografts after pancreatectomy for pancreatitis versus

43 n substitutes (CSS) and split-thickness skin autograft (AG) was performed to assess whether donor-sit

44 can match the regenerative potential of the autograft, all facets of nerve tissue must be incorporat

45 es or methods of replacement using unstented autograft, allograft, or xenograft tissue valves that be

46 Early excision with autograft-allograft closure is standard in severe burn m

47 ed to be treated with either Integra or with autograft-allograft technique.

48 tion-free survival was 96% at 2 years in the autograft/allograft group and 80% at 2 years and 75% at

49 ed two mild strokes and one pacemaker in the autograft/allograft group and three deaths and two pacem

50 vent-free survival was 96% at 2 years in the autograft/allograft group compared with 67% at 2 years a

51 Among autograft/allograft recipients, 16 patients underwent 27

52 rbidity and biocompatibility associated with autografts, allografts and synthetic grafts.

53 transplants can be roughly categorized into autografts, allografts and xenografts.

54 but in very large bone defects, traditional autograft alone is insufficient to induce repair.

55 Control osteonecrotic defects received autografts alone; test sites received autografts treated

56 Tissue biopsies from cold stored kidney autografts also failed to show evidence of peroxynitrite

57 eceived melphalan 200 mg/m2 with their first autograft and 32 patients proceeded to a second transpla

58 Islet function was compared in autograft and allograft recipients.

59 M may represent an effective replacement for autograft and BMP products used commonly in bone tissue

60 For 99 patients randomized between autograft and chemotherapy, 5-year survival was 51% in e

61 Eight autograft and eight allograft recipients, insulin indepe

62 Freedom from autograft and homograft reintervention after 15 years wa

63 t recapitulates the clinical aspects of live autograft and processed allograft healing.

64 ural and functional changes in the implanted autograft and subsequent aortic root dilatation and neoa

65 Both sites were immediately autografted and serially evaluated clinically and histol

66 hr posttransplant when transcription in both autografts and allografts was 30-fold higher than in all

67 and SOD, but not nitrotyrosine, occurred in autografts and allografts with blocked alloimmune respon

68 Current therapies, as autografts and allografts, are restricted by donor site

69 nt (ACL) reconstruction is the use of tendon autografts and allografts.

70 pective randomized trial comparing pulmonary autografts and aortic homografts who have had previous a

71 basis for engineering cerebral cortex tissue autografts and ii) a biofidelic 3D culture model for inv

72 greater in clinically accepted grafts versus autografts and in rejected grafts versus accepted (P < 0

73 demonstrates continued deterioration of the autografts and need for reoperation in a substantial per

74 The aortic media was thicker in both autografts and normal donors (P:<0.01), and there was a

75 al cultivar, Cabernet Sauvignon, using their autografts and reciprocal grafts.

76 largest and most accessible organ, epidermal autografts and tissue-engineered skin equivalents have b

77 often treated by regenerative therapy using autografts and/or allografts.

78 The best outcome procedure (autograft) and alternative options should be reviewed wi

79 ncil (UK MRC) AML protocols: 141 received an autograft, and 170 received a matched sibling allograft

80 Eventual tumor recurrence is a problem after autografting, and the development of novel maintenance c

81 hirty-seven patients had previously received autografts, and 21 were in complete remission (CR) at tr

82 more efficacious purging of tumor cells from autografts, and enhancement of autologous anti-multiple

83 -grafts-in-B6-host-allografts compared to B6-autografts, and higher modulus in MRL-autografts compare

84 ontaminating tumor cells in multiple myeloma autografts, and most importantly, the persistence of min

85 We therefore compared these outcomes after autograft aortic root replacement (Ross procedure) versu

86 (Long-Term Follow-up After the Autograft Aortic Valve Procedure [Ross Operation]; NCT00

87 f the PA (P:<0.01); however, the 4-month-old autograft appeared to show adaptation in mechanical beha

88 Although autografts are considered to be the gold standard treatm

89 Conventional meshed autografts are superior to CEA for containing hospital c

90 Histology of the thymic autografts at explantation revealed viable thymus with p

91 with L-WNT3A restored osteogenic capacity to autografts back to levels observed in autografts from yo

92 To improve autografting, better ablative regimens, more efficacious

93 bable) for GBR using a bovine bone xenograft/autograft bone composite in defects surrounding dental i

94 ue instead of sutures to anchor conjunctival autografts, but the evidence on comparative effectivenes

95 the effectiveness and risks of conjunctival autograft (CAG) compared with amniotic membrane transpla

96 e the incidence of relapse provided that the autograft can be protected by transfer of a drug-resista

97 cyte progenitor cells in cultured epithelial autografts (CEAs) regenerate human epidermis after trans

98 wever, when combined with a peripheral nerve autograft, ChABC treatment resulted in lengthy regenerat

99 to B6-autografts, and higher modulus in MRL-autografts compared to B6-graft-in-MRL-host-allografts.

100 also raises concerns about contamination of autografts contributing to relapse.

101 Five groups were studied: untreated autograft controls (n=4), untreated allograft controls (

102 The autograft controls survived indefinitely, while untreate

103 autografts, subepithelial connective tissue autografts, coronally positioned flaps, sinus augmentati

104 Limbal-conjunctival autografts could be a favored option for managing advanc

105 l grafts, we determined that 3% to 7% of the autografts could be recovered with spermatogenesis proce

106 sitive cells migrating from the keratolimbal autografts decreased rapidly during the first 4 weeks an

107 Independent risk factors for pulmonary autograft degeneration were pre-operative large aortic a

108 Whereas syngeneic tracheal autografts demonstrated normal mucociliary function afte

109 on surgical intervention with the use of an autograft, despite associated shortcomings.

110 Autograft diameter was measured early postoperatively an

111 y, analyses demonstrated that cells from the autograft directly contributed to repair of an osteonecr

112 In response to the drawbacks of autograft donor-site morbidity and bone morphogenetic pr

113 145+/-34 mL, end-systolic volume 78+/-23 mL; autografts: end-diastolic volume 157+/-33 mL, end-systol

114 Questions such as why limbal autografts fail, the long-term results of LAT, and wheth

115 The pulmonary autograft first performed by Ross came closest to achiev

116 ioning and repositioning of the conjunctival autograft (flap time) was significantly shorter in the f

117 eatment consisted of high-dose melphalan and autograft followed by 2-Gy total body irradiation, with

118 arm trial, 54 patients with myeloma received autografts followed by ex vivo anti-CD3/anti-CD28 costim

119 oplastic cells, reinfused with the remission autografts following myeloablative therapy, can potentia

120 The use of a pulmonary autograft for rereplacement of the aortic valve has both

121 All recipients also received skin autografts for comparison.

122 Patients who received unpurged autografts for low-grade NHL had a five-fold (P =.008) g

123 nts in culture that can be used as epidermal autografts for wound repair as well as for the delivery

124 Pre-treating autografts from aged animals with L-WNT3A restored osteo

125 elomere length in healed cultured epithelial autografts from four patients with burns, and noted that

126 ity to autografts back to levels observed in autografts from young animals.

127 shrinkage during healing of free soft tissue autografts (FSTAs) using different surgical techniques-s

128 luding biochemical assessment of parathyroid autograft function.

129 substitute (HF-DDS), compared to a gingival autograft (GA) consisting of donor tissue harvested from

130 Estimated peak autograft gradient was 55 mm Hg in one patient and <10 m

131 ths, 10 patients (10.0%) in the conjunctival autograft group and 1 patient (1.0%) in the limbal-conju

132 he follow-up (100 eyes from the conjunctival autograft group and 105 eyes from the limbal-conjunctiva

133 , FGF-2, and IL-8 for the LCC group over the autograft group at the early stages of wound repair.

134 tion in mortality in the cultured epithelial autograft group compared with controls, from 48% to 14%

135 1 patient (1.0%) in the limbal-conjunctival autograft group developed recurrence.

136 Two patients in the autograft group had postoperative neurological weakness;

137 At 10 years, four patients died in the autograft group versus 15 in the homograft group.

138 l survival at 10 years was 97% (SD 2) in the autograft group versus 83% (4) in the homograft group.

139 ere was one (<1%) perioperative death in the autograft group versus three (3%) in the homograft group

140 Survival of patients in the autograft group was similar to that in an age-matched an

141 up and 105 eyes from the limbal-conjunctival autograft group).

142 trend for the PA media to be thicker in the autograft group.

143 and 1 late (7 months) death occurred in the autograft group.

144 smoke inhalation in the cultured epithelial autograft group.

145 limited regarding survival, reintervention, autograft growth, and function.

146 neic transplants, and recipients of unpurged autografts had a two-fold (P =.0009) greater relapse ris

147 yes in which virally transduced keratolimbal autografts had been implanted.

148 mononuclear cell accumulations, whereas the autografts had only occasional eccentric intimal changes

149 For myeloma, reduction of tumor burden in autografts has been accomplished and been associated wit

150 ling nerve gaps, the autologous nerve graft (autograft), has several drawbacks.

151 attempts for root coverage with soft tissue autografts have resulted in residual recession defects o

152 es showed that both factors are required for autograft healing.

153 Like the pulmonary autograft, homograft AVR results in an excellent hemodyn

154 Bone regenerative engineering could replace autografts; however, no synthetic material fulfills all

155 ents randomized to receive or not receive an autograft in first CR and in a donor-versus-no donor ana

156 The future application of this form of an autograft in REPs can fulfill a yet unmet need for a sui

157 A total of 30 kidneys were autografted in six groups.

158 have been conducted to evaluate the role of autografting in acute myeloid leukemia.

159 have been conducted to evaluate the role of autografting in AML.

160 onfirm the efficacy of high-dose therapy and autografting in recurrent or refractory HD.

161 trate an advantage for high-dose therapy and autografting in the sustained control of Hodgkin's disea

162 collections of hematopoietic cells used for autografts in breast cancer patients.

163 us strategies that are being used to "purge" autografts in patients undergoing autologous bone marrow

164 n glue for the repositioning of conjunctival autografts in pterygium surgery was associated with a si

165 trachomatis infection of fimbria and ampulla autografts in subcutaneous pockets in Macaca nemestrina

166 nerve gap, with results close to that of the autografts in terms of functional and histological asses

167 In contrast, islet autografts, infused at the time of pancreatectomy for ch

168 No patient developed significant autograft insufficiency or required autograft reinterven

169 Mild autograft insufficiency was seen in 4 patients; 13 had n

170 ts receptor did not develop into tumors when autografted into immunocompetent mice.

171 bare sclera excision, conjunctival or limbal autograft, intraoperative mitomycin C, postoperative mit

172 l transplantation (SCT) after a prior failed autograft is associated with a transplant-related mortal

173 acement of the aortic valve with a pulmonary autograft is feasible and safe in patients aged 14 to 60

174 The exact rate of SVD of the pulmonary autograft is uncertain.

175 ft coverage to stabilize the wound bed until autografting is possible.

176 nizes and eliminates the cancer cells in the autografts is not understood.

177 The use of split thickness autografts is often limited by the availability of a sui

178 d regenerating human nerve from cross-facial autografts labelled with a myelin-specific fluorescent d

179 her total body irradiation or carmustine and autografting (median follow-up, 3.6 years; range, 1.1 to

180 e significantly higher in allografts than in autografts (median 3 vs. 1, P=0.042).

181 igated in the New Zealand White rabbit renal autograft model using near-infrared spectroscopy and lig

182 The kidneys were evaluated using an autograft model with immediate contralateral nephrectomy

183 ly all PBSC harvests, it is conceivable that autografted myeloma cells contribute to relapse after au

184 ortic valve replacements were performed with autografts (n = 19) or allografts (n = 6).

185 Autografts (n = 5) and SLA(cc) to SLA(cc) allografts (mi

186 tion, parallel CSS samples (n = 5) or murine autografts (n = 5) were grafted orthotopically to athymi

187 on indications for reoperation were isolated autograft (neoaortic) regurgitation in 11 cases (20), is

188 Dilatation of the autograft occurred during the first year after surgery a

189 In autografts, only class II Langerhans or dendritic-like c

190 ratolimbal explants were transduced ex vivo, autografted onto their original sites, and assessed for

191 The pulmonary autograft operation (the Ross procedure) involves excisi

192 assigned in a one-to-one ratio to receive an autograft or a homograft aortic root replacement in one

193 atients were randomly assigned to receive an autograft or a homograft aortic root replacement.

194 ies of the ACL, surgical reconstruction with autograft or allograft tissue is the current treatment o

195 ic valve replacement with either a pulmonary autograft or an aortic homograft leads to a degree of pe

196 ty-five patients undergoing either pulmonary autograft or homograft replacement of the aortic valve a

197 xcision compared with conjunctival or limbal autograft or mitomycin C alone.

198 Third-order bronchi from autografted or allografted lungs were either cut into ri

199 on of the pterygium followed by conjunctival autografting or intraoperative or postoperative mitomyci

200 rtic valve replacement in children with only autografts or allografts achieves good early results.

201 in culture and reintroduced into patients as autografts or allografts.

202 some patients were treated with insertion of autografts or allografts.

203 Use of conjunctival or limbal autografts or mitomycin C during or after pterygium exci

204 e in effect between patients who received an autograft (OR = 2.39; CIs = 1.24-4.62) and patients who

205 me patients when harvesting the conjunctival autograft, or from other patients undergoing extracapsul

206 The place of autografting, particularly now that it is possible to ob

207 nchymal stem cells (PCDSCs) from the healing autograft periosteum.

208 Aortic root autograft plus arterial switch procedure is a good optio

209 at limbus, surgical technique (conjunctival autograft plus suturing versus tissue glue), graft alter

210 g sedimentation of islets in the COBE bag in autograft preparations.

211 demonstrated that the conjunctival or limbal autograft procedure is more efficacious than amniotic me

212 s, and in bone grafts from two pigs that had autograft procedures performed.

213 In autograft purifications, more islets were recovered with

214 One autograft recipient required reoperation for pulmonary a

215 equivalents per kg body weight (IE/kg) than autograft recipients (9958+/-6229 IE/kg vs. 4589+/-1232

216 In contrast, both allo- and autograft recipients had glucagon responses to intraveno

217 The islet autograft recipients were studied 63 +/- 19 months postt

218 ipients were normoglycemic (fasting glucose: autograft recipients, 5.6 +/- 0.1 mmol/l; allograft reci

219 cose excursion were similar in allograft and autograft recipients, despite the latter group receiving

220 0 and 40 infusions per year in allograft and autograft recipients, respectively.

221 guiding antiviral treatment in seropositive autograft recipients.

222 patients-1855 (55%) allograft and 1524 (45%) autograft recipients.

223 er significantly between islet allograft and autograft recipients.

224 ipients to a greater extent than in those of autografted recipients.

225 that mitomycin C and conjunctival or limbal autografts reduce the recurrence rate after surgical exc

226 rgitation/dilatation in 8 (14), and combined autograft regurgitation and pulmonary conduit regurgitat

227 t regurgitation/stenosis in 9 (16), combined autograft regurgitation/dilatation in 8 (14), and combin

228 nificant autograft insufficiency or required autograft reintervention during the follow-up period.

229 dysfunction was 87% at 8 years; freedom from autograft reintervention was 100%.

230 ention was 71.1% (95% CI, 61.6%-82.0%); from autograft reintervention, 80.3% (95% CI, 71.9%-89.6%); a

231 F are necessary and sufficient for efficient autograft remodeling and can be transferred using rAAV t

232 Freedom from autograft reoperation at 10 years was 82% (95% CI: 64.1%

233 superior long-term survival and freedom from autograft reoperation compared with primary Ross procedu

234 e better long-term survival and freedom from autograft reoperation.

235 ansduces all Hh signals at the onset of bone autograft repair via a tamoxifen-inducible RosaCreER mou

236 After pulmonary autograft replacement of the aortic valve and root, the

237 Survival after autograft replacement of the AV (Ross Operation) was sig

238 yclophosphamide and rATG with a non-selected autograft results in sustained improvement in skin thick

239 ther techniques, such as implantation of the autograft root within a synthetic vascular graft, are kn

240 omograft, stented heterograft, and pulmonary autograft (Ross procedure), and none of the available va

241 The pulmonary autograft (Ross) technique for aortic valve replacement

242 human dental pulp to be used as a potential autograft scaffold.

243 .1 cm/s, LR 6.0+/-1.8 versus 8.9+/-3.0 cm/s; autografts: SE 1.4+/-0.4 versus 2.2+/-0.4 cm, SR 5.8+/-3

244 Four autografts served as control samples, having received no

245 Better preservation of islet mass in the autograft setting is likely related to the lack of autoi

246 Autografts showed no evidence of rejection.

247 s has substantially reduced the morbidity of autografting, so that disease relapse now represents the

248 Marrow autograft studies showed gut toxicity as limiting MMF si

249 ant surgery, epithelialized free soft tissue autografts, subepithelial connective tissue autografts,

250 the end product will be the equivalent of an autograft such that the recipient will not require any a

251 eries of 18 patients who underwent pulmonary autograft surgery and 8 normal organ donors, samples fro

252 orta from 9 patients who underwent pulmonary autograft surgery and from 1 patient in whom a 4-month-o

253 dergone either aortic homograft or pulmonary autograft surgery were studied between 6 and 35 months a

254 Islet function is more resilient in autografts than allografts.

255 cause of death after a melphalan-conditioned autograft, the mechanism remains unclear.

256 Periodontists have found the gingival autograft to be an effective and predictable technique t

257 The establishment of a thymokidney by thymic autografting to the renal subcapsular space results in n

258 ian age 7 months) have undergone aortic root autograft translocation plus arterial switch to correct

259 current pterygia underwent free conjunctival autograft transplant (112 eyes) or limbal-conjunctival a

260 transplant (112 eyes) or limbal-conjunctival autograft transplant (112 eyes).

261 le to the established method of conjunctival autograft transplantation (CG) and it is especially indi

262 Patients who have undergone autograft transplantation after TBI-containing regimens

263 Recent clinical studies on limbal autograft transplantation also underscore the importance

264 Here we performed a pig kidney thymic autograft transplantation from an alpha1,3-galactosyltra

265 ceived autografts alone; test sites received autografts treated ex vivo with L-WNT3A.

266 nse of autologous BMT, suggest that delay of autograft until second remission in these two groups may

267 More aggressive T cell depletion of the autograft, use of a myeloablative regimen, or use of an

268 tcome of pterygium surgery with conjunctival autograft using Vicryl sutures (Ethicon, NJ), Evicel fib

269 The autograft valve required replacement in 21 cases (38) an

270 ere was a trend toward inferior survival for autograft versus chemotherapy (OR = 1.18; 95% CI, 0.99-1

271 randomization) and from randomized trials of autograft versus chemotherapy.

272 ery and from 1 patient in whom a 4-month-old autograft was explanted.

273 Limbal conjunctival autograft was more effective than intraoperative MMC in

274 Total parathyroidectomy with parathyroid autograft was performed in 26 of 34 primary procedures.

275 One patient who received a pulmonary autograft was reoperated on for inflammatory pulmonary s

276 Conjunctival or limbal autograft was superior to amniotic membrane graft surger

277 Conjunctival autograft was the predominant surgical technique (94%),

278 No beneficial effect of autografting was seen compared with chemotherapy in this

279 Finally, function of cold stored canine autografts was not affected by the scavenging of peroxyn

280 The same figures for patients undergoing autograft were 80.8% and 89.3%, respectively.

281 Control values for murine autograft were 870 +/- 245 pF at 2 wk, and 87 +/- 30 pF

282 ment with an aortic homograft or a pulmonary autograft were followed up echocardiographically for up

283 The outcomes of conjunctival or limbal autograft were similar to outcomes for intraoperative mi

284 dergoing pterygium surgery with conjunctival autografting were randomized into groups receiving 10-0

285 Allografts or autografts were harvested serially 3-90 days after trans

286 adjacent wounds, 0.005- or 0.017-inch-thick autografts were implanted.

287 Pancreatic tissue densities from autografts were significantly higher than in allograft p

288 However, CML autografts will almost certainly contain malignant stem

289 In the autograft with 16 sutures, the 20% wt/vol of the ([G1]-P

290 In the autograft with eight sutures, the ([G1]-PGLSA-MA)(2)-PEG

291 pterygium excision with conjunctival-limbal autograft with fibrin glue application was done.

292 sing a combination of conjunctival or limbal autograft with mitomycin C further reduces the recurrenc

293 Autografting with in vivo-purged stem cells may induce p

294 Autografting with Philadelphia-negative progenitor cells

295 The pulmonary autograft, with its native aortic valve properties, has

296 en high-dose cyclophosphamide is used alone, autografting, with its potential for reinfusing autoreac

297 n of antitumor effector cells in a mobilized autograft without impairing the hematologic engraftment,

298 g throughout the hospital stay, prompt sheet autograft wound closure as soon as practical, and the se

299 Autografting yielded significantly more relapse (68%; 95

300 In a subgroup, the mean autograft z score increased significantly from the posto