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1 sibility that the observed shedding could be autolytic.
2 kedly enhanced (>50-fold) the intermolecular autolytic activation of promatrilysin and the activity o
3                                   Similarly, autolytic activation of promatrilysin in vitro can take
4 hin A23187-treated cells remained capable of autolytic activation upon treatment with p-aminophenylme
5 ant revealed that CaM binding enhanced CAPN3 autolytic activation.
6                        The results add major autolytic activities to the growing list of functions co
7 led altered cell morphologies and effects on autolytic activity and antibiotic susceptibilities that,
8                This protein also affects the autolytic activity and lysostaphin sensitivity of the ba
9 lucosamine, fibronectin-binding proteins, or autolytic activity and were antibiotic resistant.
10 f-reinforcing cycle that gradually increases autolytic activity as cytokinesis progresses.
11 s, changes in cell-wall cross-linking and/or autolytic activity can modulate PLA2 action either by af
12 oduct (34.4 kDa) corresponded to that of the autolytic activity detected (approximately 36 kDa) in th
13 at gene product is an important regulator of autolytic activity in S. aureus.
14 ouble mutant strain also exhibited increased autolytic activity in the presence of detergents.
15 s showed slow growth, and strongly decreased autolytic activity that appeared to be mainly due to dec
16 rmissive for other gonococcal autolysins, an autolytic activity was detectable in the wild-type strai
17                           A gene encoding an autolytic activity was identified in an autolysis-defici
18         The effects of protonmotive force on autolytic activity were studied by adding cell wall prot
19 d a 70-fold increase in bovine factor X(a)'s autolytic activity, consistent with the 60-fold increase
20 within the cell envelope, severely decreased autolytic activity, resistance to lysis by S. aureus pha
21                        Besides its effect on autolytic activity, we recently found alterations in the
22  biofilm was released extracellularly due to autolytic activity.
23 al, as the first positive regulator of CAPN3 autolytic activity.
24 ion of a disulfide bond that is required for autolytic activity.
25 uman MBP, but not an MBP fragment that lacks autolytic activity.
26  the gene likely or proven to be involved in autolytic activity.
27 eins, IsaA and SceD, were both found to have autolytic activity.
28 this gene rat, which stands for regulator of autolytic activity.
29 binding protein to these known repressors of autolytic activity.
30 coli clones carrying the lytM gene exhibited autolytic-activity bands of approximately 36 kDa as well
31  aureus which produces only a single band in autolytic-activity gels.
32 e LytR modulates the expression of the major autolytic amidase and CsbB may function in peptidoglycan
33 d from the solid phase using metal-mediated, autolytic amide bond cleavage (MMAAC).
34                                      Various autolytic and cross-activation relationships identified
35                              The GH25 is non-autolytic and exhibits lysozyme-mediated lytic activity
36 , thereby preventing relief of repression of autolytic and other cell death functions in response to
37                             Despite possible autolytic artifacts due to technical and experimental co
38                          This truncation was autolytic as illustrated by its R199A/R200A or E346A mut
39 long chains by the cells, markedly decreased autolytic capacity, poor biofilm formation, diminished t
40 veral nonenveloped animal viruses possess an autolytic capsid protein that is cleaved as a maturation
41  Neisseria autolysis peptides (Naps) promote autolytic cell death when bacteria enter the stationary
42 e show that NLRP1 activity is dependent upon autolytic cleavage at Ser(1213) within the FIIND.
43 -barrel head domains in the mu1 trimer, (ii) autolytic cleavage at the mu1N/C junction, associated wi
44                                              Autolytic cleavage divides Mu1 into myristoylated Mu1N a
45      Previous evidence has suggested that an autolytic cleavage in mu1 allows the release of its N-te
46 , coupling exposure of the fatty acid chain, autolytic cleavage of Mu1N, and long-range molecular rea
47          Thiol oxidation was associated with autolytic cleavage of pro-MMP-7, strongly suggesting tha
48                                              Autolytic cleavage of the helicase site was insensitive
49                                              Autolytic cleavage reactions also occurred in NS2B-NS3 r
50                                              Autolytic cleavage releases a positively charged moiety
51 alytic domain to the hinge region and to the autolytic cleavage site and protects MT1-MMP from autoly
52 s of CTRC cleavage sites Leu-81 and Leu-148, autolytic cleavage site Arg-122, and restoration of the
53                                              Autolytic cleavage to form micro1N is required for hemol
54                                              Autolytic cleavage within the caspase-12 proenzyme was m
55                                         Upon autolytic cleavage, the Myrf N-terminal fragment enters
56 tion could render cathepsin G susceptible to autolytic cleavage.
57                    With these materials, the autolytic cleavages were found to be intramolecular only
58                   The protease catalyzed two autolytic cleavages.
59 m in the presence or absence of oxidant, and autolytic conversion of both the 80- and 30-kDa subunits
60                                 In addition, autolytic conversion of either the 80- or 30-kDa subunit
61                                              Autolytic conversion of the 80-kDa subunit of calpain I
62                                  The rate of autolytic conversion of the large subunit of calpain I f
63 restingly, whereas oxidation did not inhibit autolytic conversion, the presence of high substrate con
64                                Insignificant autolytic degradation is characteristic for naturally ex
65 he common carp alpha1-PI effectively reduced autolytic degradation of bigeye snapper surimi at the co
66 ssociation at low enzyme concentrations, and autolytic degradation of the p10 subunit at high concent
67  was stabilized greater than 80-fold against autolytic degradation relative to wild-type N-His ICE.
68 Glu was added to eliminate the major site of autolytic degradation while maintaining catalytic activi
69                           In turn, extensive autolytic degradation, which leads to the inactivation o
70  pancreatitis by stabilizing trypsin against autolytic degradation, while the mechanism of action of
71                                              Autolytic DNA breakdown, detected as smears in electroph
72 m of action, and neither interfered with the autolytic effects of vancomycin.
73                        Similar repression of autolytic enzymatic activity and transcription was also
74 ked the in vitro hydrolysis of cell walls by autolytic enzyme extracts, lysostaphin and mutanolysin.
75                          Our analysis of the autolytic enzyme repertoires of these pathogens reveals
76  pipeline to create and analyze databases of autolytic enzyme sequences, constituent domain annotatio
77 mbination between DNA encoding bacteriophage autolytic enzymes and chromosomally encoded lytA might b
78 d macromolecule during growth, but how these autolytic enzymes are regulated remains poorly understoo
79 wever, it is not known how these potentially autolytic enzymes are regulated to prevent lethal breach
80 creased in vitro hydrolysis of cell walls by autolytic enzymes due to hypo-cross-linked peptidoglycan
81 hubs coordinating the activities of multiple autolytic enzymes during cell constriction and fission r
82      The aim of this study was to inactivate autolytic enzymes in C. finmarchicus by applying heat (7
83    Therefore, the expression and activity of autolytic enzymes must be tightly regulated in growing c
84 inappropriately upregulating the activity of autolytic enzymes that weaken the cell wall.
85 ope-dependent processes, such as activity of autolytic enzymes, binding of divalent cations, and susc
86 cal role for a widely misunderstood class of autolytic enzymes, lytic transglycosylases (LTGs).
87 on and enzymatic activities of several major autolytic enzymes.
88 during growth may be one means of regulating autolytic enzymes.
89  vitro hydrolysis of resistant cell walls by autolytic extracts prepared from either susceptible or r
90                    However, the enterococcal autolytic factors GelE and Atn (also known as AtlA), whi
91                            Sequencing of the autolytic fragments showed loss of three amino acids fro
92 nd, contrary to prevailing models, that this autolytic function can be temporally separate from pepti
93 is similar and suggesting that modulation of autolytic function may be similar.
94 imers generated from gene sequences of known autolytic genes of S. aureus clearly indicate that the l
95 M gene is distinct from other staphylococcal autolytic genes reported to date.
96  is LasA, an M23 metallopeptidase related to autolytic glycylglycine endopeptidases such as Staphyloc
97   Also, the cleavage pattern and kinetics in autolytic inactivation of both KLK2 variants can be expl
98 le when compared to the rate of the internal autolytic inactivation or to the ability of other protea
99                                          The autolytic Lys-Lys-Gln(59) downward arrow Gln(60)-Phe-His
100         Here, we comprehensively analyze the autolytic machinery of the alphaproteobacterial model or
101 upport a role for VncRS in the regulation of autolytic or other putative cell death loci.
102 s also shed efficiently, thus ruling out the autolytic pathway.
103 ile overexpression of mcrA caused the fluffy-autolytic phenotype coupled with accelerated cell death,
104                                    Also, the autolytic phenotype in the arlRS mutant of MSSA strain N
105                               We describe an autolytic postmortem histologic artifact of eosinophilic
106 oss of bacterial viability, indicative of an autolytic process.
107 te the active amino terminal fragment, by an autolytic process.
108 nmarchicus rapidly changes postmortem due to autolytic processes; in particular phospholipids rapidly
109                                 Although the autolytic processing and interstitial collagenase activi
110 t lacking exon 14 differentially affect this autolytic processing and subsequent NLRP1 activity.
111  to perform common functions as catalysts of autolytic processing following cell death due to program
112                   Rather, APMA inhibited the autolytic processing in these mutants, further confirmin
113                             Three sequential autolytic processing steps at the N and C terminus are r
114 synchrotron small-angle X-ray scattering, 3' autolytic processing, and hydroxyl radical protection.
115 e to the organomercurial APMA by accelerated autolytic processing.
116       3,3'-Diindolylmethane (DIM), a natural autolytic product in plants of the Brassica genus, inclu
117                                The identical autolytic profile was obtained using a sortase mutant (S
118 trypsin enables the proteolytic activity and autolytic properties of the enzyme to be studied.
119 structural change in the capsid that induces autolytic protease activity.
120 gical markers and the expression of putative autolytic proteases.
121 mutant was linked to an observed increase in autolytic rate compared to the parental strain.
122 otonated, and proton-motive force influences autolytic regulation in both TUA-containing and TA-conta
123 at resulted in decreased expression of known autolytic regulators lytSR, lrgAB and arlRS.
124       The results thus show that the primary autolytic regulatory mechanism of KLK6 is negative feedb
125  we demonstrate that metal complex-mediated, autolytic release of active metallodrugs can be successf
126 of KLK6 toward its pro-sequence and internal autolytic sequence is characterized.
127 er subsegment containing a potential calpain autolytic site severely disturbs gametophore development
128 n-cysteine, cellular proteases acting on the autolytic sites of CAPN3, rather than autolysis.
129                             Two of the major autolytic sites were Leu(49)-Thr(50) and Ala(75)-Leu(76)
130  it has no effect on catalytic properties or autolytic stability of trypsin.
131 elE-expressing E. faecalis strains were more autolytic, suggesting that GelE affects chain length thr
132 f S. aureus induces strong repression of the autolytic system and provide evidence for transcriptiona
133  of cell wall synthesis on the status of the autolytic system in Staphylococcus aureus.
134 eria modulate their PGN degradation by their autolytic system or their recognition by the mammalian i
135 tides), which are generated by the bacterial autolytic system, are usually transported into the cytop
136 arA double mutants of both strains were more autolytic than the single mutants in vitro.
137 as viable and grew normally, but it was less autolytic than the wild-type strain in stationary-phase
138 s, we documented that BlaR1 fragmentation is autolytic, that it occurs in the absence of antibiotics,
139 poor, hyphal osmotrophs outcompete motile or autolytic unicellular osmotrophs.

 
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