ライフサイエンスコーパス: autophagy-related protein

1 ides) are PtdIns3P and PtdIns(3,5)P2 binding autophagy related proteins.

2 tributed in part to defective recruitment of autophagy-related proteins.

3 s and enhances autophagic flux by modulating autophagy-related proteins.

4 or intrinsically disordered regions of many autophagy-related proteins.

5 ophagic flux, and led to the accumulation of autophagy-related proteins.

6 phore assembly site and interacted with Atg (autophagy related) proteins.

7 vating kinase (Ulk)2, a homolog of the yeast autophagy related protein 1, as particularly enriched in

8 TAZ domain-containing protein gene (SlBT1), AUTOPHAGY-RELATED PROTEIN 11, ACYLSUGAR ACYLTRANSFERASE

9 ory complex, including the essential subunit autophagy-related protein 13 (ATG13).

10 Here, we show that the host autophagy-related protein 16-1 (ATG16L1) restricts inclu

11 ptor-interacting protein kinase 2 (RIP2) and autophagy-related protein 16-1 (ATG16L1).

12 t is a locus on chromosome 10 containing the autophagy-related protein 18 (ATG18) associated with dec

13 phagy receptors, such as the Pichia pastoris autophagy-related protein 30 (Atg30), which controls the

14 g the candidates, the host cysteine protease autophagy-related protein 4 homolog B (ATG4B), a key com

15 unoblot and in GFP-LC3 transgenic mice), and autophagy-related protein 5 protein expression.

16 n expression of autophagy markers LC3 II and autophagy-related protein 5.

17 eracting serine-threonine kinase-2 (RIPK-2), autophagy-related protein-5 (ATG5), ATG7 and ATG16L1 but

18 Using autophagy-related protein 7 (Atg7) as an autophagic mark

19 autophagy-related protein beclin 1 (BCN1) or autophagy-related protein 7 (ATG7) in immortalized human

20 Atg7(Deltapan) mice that lack the essential autophagy-related protein 7 (ATG7) in pancreatic epithel

21 patocytes, autophagy was inhibited by 3MA or autophagy-related protein 7 (Atg7) small interfering RNA

22 Expression of autophagy-related protein 7 (Atg7), Beclin-1, and Atg12,

23 es, vacuolar protein sorting 34 (VPS34), and autophagy-related protein 7 (ATG7), could rescue the PA-

24 phagy, correlated with increased Beclin1 and autophagy-related protein 7 (Atg7), proteins involved in

25 Similarly, knock down of autophagy-related protein 7 and TLR7 by use of siRNA sig

26 ethyladenine (3-MA) or were transfected with autophagy-related protein 7 or TLR7 small interfering RN

27 autophagy as defined by the requirement for autophagy-related protein 7.

28 may utilize autophagy for replication as the autophagy-related protein-7 (ATG-7), microtubule-associa

29 Here we describe a novel interaction between autophagy-related protein 8 (Atg8) and fatty acid syntha

30 Autophagy-related protein 8 (ATG8) is a highly conserved

31 The NMAS1 effectors contain predicted AuTophaGy-related protein 8 (ATG8)-interacting motif (AI

32 uman macrophages is the signal that triggers autophagy-related protein 8/microtubule-associated prote

33 Autophagy-related protein 9 (ATG9) vesicles seed the gro

34 evisiae, the integral membrane protein Atg9 (autophagy-related protein 9) cycles between mitochondria

35 en the sole transmembrane autophagy protein, autophagy-related protein 9A (ATG9A), and components of

36 lyses of the functions and dynamics of known autophagy-related proteins and for screening new genes.

37 ces of these effects on H4K20me1, mTOR-, and autophagy-related proteins and mRNAs expression in human

38 rmal POS clearance and altered expression of autophagy-related proteins and Rab22a, a regulator of en

39 However, autophagy-related proteins are also essential for the ea

40 These data indicate that multiple autophagy-related proteins are important for one or more

41 found that ER content is expanded in mature autophagy-related protein (Atg) 7-deficient T lymphocyte

42 ential components of the autophagic pathway, autophagy-related protein (Atg)5, Beclin1, and Ulk1, wer

43 otubule-associated protein 1B-light chain 3, autophagy-related protein (ATG)7, ATG2b, and autophagoso

44 We analyzed changes in autophagy-related proteins (Atg).

45 ovide cardioprotection in mice that lack the autophagy-related protein Atg5 in cardiomyocytes.

46 y, reduces lipid accumulation, and increases autophagy-related proteins ATG5, ATG7, and light chain 3

47 ed the previously described functions of the autophagy-related proteins Atg5-Atg12, but NLRX1 did not

48 t affected by E. faecalis, expression of the autophagy-related proteins ATG7, Beclin1, and LC3bI/II w

49 gested that high expression of the essential autophagy-related protein, Atg7, was associated with sho

50 important substrates of Ubp15, including the autophagy-related protein Atg8, the mitogen-activated pr

51 ORM proteins interact with FLS2 and the autophagy-related protein ATG8.

52 The identification of conserved autophagy-related proteins (ATGs) that mediate bulk degr

53 In this study, we found that knockdown of autophagy-related protein beclin 1 (BCN1) or autophagy-r

54 smodium vivax depends only on the downstream autophagy-related proteins Beclin 1, PI3K, and ATG5, but

55 We report that a recently discovered autophagy-related protein, Beclin 2, interacts with KSHV

56 Autophagy-related proteins (BECN1, ATG5, ATG7, lipidated

57 Here, we found that an autophagy-related protein Becn2 is a previously unidenti

58 ing compartment by a mechanism that involved autophagy-related proteins, but not the conventional aut

59 tion or knockdown of presenilins alters many autophagy-related proteins demonstrating a buildup of au

60 Recently, the autophagy-related protein, double FYVE domain-containing

61 and by measuring LC3B protein lipidation and autophagy-related protein expressions.

62 Western blot analysis indicated that several autophagy-related proteins fluctuated during the procedu

63 fferential expression and phosphorylation of autophagy-related proteins in ASD but further investigat

64 y to its substrates (TP53 in the nucleus and autophagy-related proteins in the cytoplasm).

65 Early and sustained expression of autophagy-related proteins in this genetically precise m

66 Emerging studies hint at the roles of autophagy-related proteins in various cellular processes

67 e reductions in the liver levels of some key autophagy-related proteins, including Atg5, Atg7, Beclin

68 also reduced oxidative stress and modulated autophagy-related proteins, increasing Beclin1, LC3-II,

69 To understand if autophagy-related proteins influence genome stability, w

70 teraction between HCK and ATG2A and CBL, two autophagy-related proteins, inhibiting autophagy flux in

71 s well as the selective regulation of single autophagy-related protein isoforms, are considered as th

72 ubiquitin-binding protein SQSTM1/p62 and the autophagy-related protein LC3, silencing of p62 and LC3

73 We observed recruitment of the autophagy-related protein LC3-II to the phagosome, where

74 he proximal tubules and reduced ratio of the autophagy-related protein LC3-II/I in the kidney post-UU

75 We found that the autophagy-related proteins LC3 and p62 localized to wild

76 ar calcium overload that is dependent on the autophagy-related proteins LC3 and p62 upon hyperactivat

77 prE (Mtb) mutant also led to accumulation of autophagy-related proteins (LC3, Atg-5, and Beclin-1) an

78 us produced strong accumulation of lipidated autophagy-related protein LC3B (LC3B-II).

79 ganese superoxide dismutase-2 (SOD2) and the autophagy-related proteins LC3II and Gabarapl1 also are

80 gic cargo SQSTM1/p62 and decreased levels of autophagy-related proteins LC3II, Beclin1, and Atg7.

81 during Plasmodium infection and the roles of autophagy-related proteins may provide an urgently neede

82 of autophagic vacuoles and conversion of an autophagy-related protein, microtubule-associated protei

83 expression and on PHF8, H4K20me1, mTOR-, and autophagy-related proteins/mRNAs in HUVEC.

84 the expression of miR-22-3p, Phf8, mTOR- and autophagy-related proteins/mRNAs in vivo in hearts of Cb

85 Ubiquitination of autophagy-related proteins or regulatory components is i

86 To identify drugs that reduce levels of the autophagy-related protein p62/SQSTM1 in cystinotic proxi

87 is paralleled by increased expression of the autophagy-related protein, p62.

88 The recruitment of autophagy-related proteins plays a key role in multiple

89 embryonic fibroblasts deficient in Atg5, an autophagy-related protein required for autophagosome for

90 ient neurons double stain with ubiquitin and autophagy related proteins, resembling the pathological

91 es autophagy by acting directly on essential autophagy-related proteins strategically located in the

92 genous and induced clusters co-localize with autophagy-related proteins such as Atg16L1, LC3B and Rab

93 Autophagy-related proteins such as Beclin-1 are involved

94 ics revealed unique phosphorylation sites in autophagy-related proteins such as ULK2, RB1CC1, ATG16L1

95 rotein synthesis, including that of specific autophagy-related proteins that are up-regulated in resp

96 ytoplasmic accumulation of active Lyn and of autophagy-related proteins Ulk1 and Atg7.

97 e PKA-RI adapter SPHKAP, and the ER-resident autophagy-related proteins VAPA/B, which co-adapt and me

98 While autophagy-related proteins were shown to influence the s

99 or with small interfering RNAs specific for autophagy-related proteins, which are essential for auto

100 to their autophagy function, several of the autophagy-related proteins work at the interface of othe