ライフサイエンスコーパス: autoregulate

1 ed FFAs impaired the ability of the liver to autoregulate.

2 have demonstrated that sigU transcription is autoregulated.

3 It also depended on sigN, thus sigN was autoregulated.

4 onstrate that yefM-yoeB is transcriptionally autoregulated.

5 tested, indicating that frp transcription is autoregulated.

6 ed if mutated and so appear to be negatively autoregulated.

7 nd we demonstrated that expression of cmr is autoregulated.

8 of SUF14 mRNA, suggesting that expression is autoregulated.

9 ally regulated by DNA damage and p53, and is autoregulated.

10 rolled in a Pdr1p/Pdr3p-dependent manner and autoregulated.

11 ied a specific transcript that is positively autoregulated.

12 this report suggest that SarA expression is autoregulated.

13 e operons might be negatively and positively autoregulated.

14 g that the expression of sigM was positively autoregulated.

15 of the group A streptococcus, is positively autoregulated.

16 that this transcription factor is positively autoregulated.

17 in vitro, indicating that sigR is positively autoregulated.

18 milar, we conclude that the sde locus is not autoregulated.

19 pstream of rpoE1, suggesting the gene may be autoregulated.

20 ity in the full-length protein is negatively autoregulated.

21 diversity of how the HigB-HigA TA family is autoregulated.

22 ia coli transcription factors are negatively autoregulated.

23 o report that E. coli fabR expression is not autoregulated.

24 from two promoters, one constitutive and one autoregulated.

25 nsive promoters; only promoter P(A4) is PhoP autoregulated.

26 The otx gene also autoregulates.

27 that transcription from the INO2 promoter is autoregulated 12-fold in a manner identical to that of t

28 determine if the TrcR response regulator is autoregulated, a trcR-lacZ fusion plasmid and a TrcR exp

29 pilA was also autoregulated; a mutation which altered an invariant glu

30 For example, N-terminal regions of NBCe1 autoregulate activity.

31 mRNAs from the exuperantia and att genes and autoregulates alternative splicing of its own pre-mRNA.

32 riptional activity such that sc is unable to autoregulate, an essential function for the segregation

33 hila homologs of mammalian SRp20, negatively autoregulate and crossregulate at the level of alternati

34 The aphA promoter is also negatively autoregulated and an AphA binding site is centred at -20

35 rther, we demonstrate that vfr expression is autoregulated and cAMP dependent and involves Vfr bindin

36 ested that both BlxR and VjbR are positively autoregulated and cross-regulate the expression of each

37 The Nmp4/CIZ promoters are autoregulated and deletion analysis identified regions t

38 CRT1 is autoregulated and is itself induced by DNA damage, indic

39 The results indicate that AF1298 is autoregulated and is part of an operon with two downstre

40 The arsR gene is autoregulated and is typically part of an operon that co

41 ulation and further suggest that TPBF may be autoregulated and may participate in the regulation of t

42 genes, suggesting that agr-like genes may be autoregulated and that they regulate gelE and sprE expre

43 Characteristic of other TA modules, shpAB is autoregulated, and high persistence depends on the Lon p

44 emonstrate that the transcription of rdgA is autoregulated, and strongly support the idea that proteo

45 r locus, fsrA, fsrB, and fsrC, appears to be autoregulated, and we have shown that mutants with inser

46 e; phoP, indicative that the phoPQ operon is autoregulated; and an open reading frame encoding a prot

47 tudies demonstrated that the parDE operon is autoregulated as a result of the binding of the ParD pro

48 rly at 40 degrees C, suggesting a failure to autoregulate at high-input states.

49 operon (rnc operon) expression is negatively autoregulated at the level of message stability by ribon

50 nce master regulator ComK is also positively autoregulated at the level of transcription and negative

51 ma-proteobacteria, E. coli Sxy is positively autoregulated at the level of transcription by a mechani

52 The B. subtilis rho gene was autoregulated at the level of transcription; autoregulat

53 We hypothesized that kinins autoregulate B2R and B1R expression in favor of B1R.

54 The vascular endothelium acutely autoregulates blood flow in vivo in part through unknown

55 and suggest that ApxR not only is positively autoregulated but also acts as a transcriptional regulat

56 ystem whereas the ytbRI system is positively autoregulated but only at the level of ytbI expression.

57 The transcription of abh is not autoregulated, but it is subject to a degree of AbrB-aff

58 nt manner, and cinI expression is positively autoregulated by 3OH,C14:1-HSL, the only identified N-ac

59 FUS levels are autoregulated by a mechanism in which human FUS downregu

60 10 by THP-1 cells stimulated with L-OspA was autoregulated by a negative feedback mechanism involving

61 We further show that nusA is autoregulated by a transcription attenuation mechanism t

62 Thus, IRF7 transcription is autoregulated by binding of the IRF7-containing VAF to i

63 exhibited by mammalian family members and is autoregulated by cisacting inhibitory domains.

64 ests that EBNA gene transcription is largely autoregulated by EBNA 1 and EBNA 2.

65 The expression of ecxR was positively autoregulated by EcxR.

66 Transcription of the rpoE gene is positively autoregulated by Esigma(E) and by unknown mechanisms tha

67 Tubulin concentration is autoregulated by feedback control of messenger RNA (mRNA

68 Yeast ribosomal protein gene RPL7B is autoregulated by inhibition of splicing.

69 also found that INO4 gene expression is not autoregulated by Ino2p and Ino4p, despite the presence o

70 ously demonstrated that Plk4 accumulation is autoregulated by its own kinase activity.

71 ing growth with tryptophan and that they are autoregulated by kynurenine.

72 servations suggest that Grp1 family GEFs are autoregulated by mechanisms that depend on plasma membra

73 wo main promoters (P0 and P1), and these are autoregulated by Pax6.

74 provide information on how this promoter is autoregulated by proteins within the locus.

75 at lozenge-lacZ reporter-gene expression was autoregulated by Serpent and Lozenge.

76 BMP signalling is negatively autoregulated by several genes including SMAD6, Noggin a

77 s the downstream promoter, P2, is positively autoregulated by sigma(E).

78 ntral domain of ARHGEF17 with Mps1, which is autoregulated by the activity of Mps1 kinase, for which

79 The abiE operon was negatively autoregulated by the antitoxin, AbiEi, a member of a wid

80 Transcription of the three TA operons was autoregulated by the antitoxins.

81 ro, repressed by the addition of zinc and is autoregulated by the copper-responsive CopY repressor pr

82 ypical toxin-antitoxin system, is negatively autoregulated by the products of the operon.

83 ur inducing (Ti) plasmids is both negatively autoregulated by the RepA and RepB proteins, and positiv

84 m crown gall tumours, and is also positively autoregulated by TraR and AAI.

85 Although eIF1 autoregulates by discriminating against poor context in

86 liloti, and it is expressed similarly to the autoregulated C. crescentus ctrA in that both genes have

87 hat CCt, a proteolytic fragment of Ca(V)1.2, autoregulates Ca(V)1.2 expression in cardiac myocytes.

88 in a broad concentration range, yielding an autoregulated catalytic system.

89 More generally, by wiring positively autoregulated chromatin modification circuits under time

90 mal anxiety-related behaviors through direct autoregulated control of serotonergic gene expression.

91 olecular Cell, Badis et al. demonstrate that autoregulated destabilization of the RPS28B mRNA is medi

92 flow to CP of the fourth ventricle does not autoregulate during nonpharmacological increases in AP.

93 ood flow to the CP of the lateral ventricles autoregulates during nonpharmacological or pharmacologic

94 iRNAs are expressed late during infection to autoregulate early gene expression.

95 lated by two known enhancers: the early (non-autoregulating) element and the autoregulatory element.

96 e which overlaps the promoter and implies an autoregulated expression of RepB.

97 GFR/Ret signaling, in turn, autoregulates expression of both GFRalpha1 and GFRalpha2

98 coli ribonuclease III (RNase III) negatively autoregulates expression of its own gene (rnc) approxima

99 er transcription factor Pdr3p, which in turn autoregulates expression of its structural gene.

100 reas hipB encodes a DNA-binding protein that autoregulates expression of the hip operon and binds to

101 ssed as a monocistronic transcript, and EtrB autoregulates expression.

102 he cardiac L-type calcium channel (Ca(V)1.2) autoregulates expression.

103 tmitotic neurons by the sustained, and often autoregulated, expression of the same transcription fact

104 polyadenylation/3' processing to negatively autoregulate FCA.

105 , our data demonstrate that homodimerization autoregulates FGF9 and FGF20's receptor binding and conc

106 due to an inhibition of transcription of the autoregulated G1 cyclins, CLN1 and CLN2; the transcripti

107 ed the behaviour of an inducible, negatively autoregulated gene circuit arranged in different transcr

108 or of the dynamics and the noise behavior of autoregulated gene circuits, and this T-based technique

109 nalysis of intrinsic noise within negatively autoregulated gene circuits.

110 We examine the response of an autoregulated gene to the total number of transcription

111 We evaluated the ability of an autoregulated gene, antitat, to inhibit replication of s

112 lator in defining the output of a positively autoregulated genetic circuit.

113 ression of an insertion mutant allele and to autoregulate genomic su(s) transgenes.

114 ylase-expressing neurons that is critical to autoregulate GH secretion via a negative-feedback loop.

115 S-Glutathionylation on Cys47 and Cys101 autoregulates GSTpi, breaks ligand binding interactions

116 TFs that autoregulate have more interactions with microRNAs than

117 define a novel transcriptional mechanism of autoregulated homeostasis of BRCA1 that selectively titr

118 PG produced through COX-2 also autoregulate IL-12, but the effects are dependent on the

119 Phytochrome message was negatively autoregulated in a specific region within the root cap.

120 ing the likelihood that PNPase expression is autoregulated in an RNase III-dependent manner in S. coe

121 e named rctBp was identified and found to be autoregulated in Escherichia coli.

122 lls and tissues, GR expression is positively autoregulated in human leukemic T cells and in other cel

123 romoter, raising the likelihood that tylP is autoregulated in its native host, Streptomyces fradiae.

124 t BMP4-dependent transcription is negatively autoregulated in part by SIN3B alternative splicing, and

125 vel promoter structure and may be positively autoregulated in response to environmental stress.

126 The PDR3 gene is positively autoregulated in rho(0) cells by virtue of the presence

127 viduals demonstrated that punc is negatively autoregulated in some tissues.

128 CE2 is shown to be autoregulated in the diencephalon, responding to absence

129 nderstood group of LTTRs that are positively autoregulated in the presence of a ligand.

130 start points, shown that CarR is positively autoregulated in the presence of OHHL, and have demonstr

131 ABI5 expression is autoregulated in transgenic plants and yeast (Saccharomy

132 e show that the cdk-inhibitor p21(Waf1/Cip1) autoregulates in a positive fashion transcription throug

133 cistronic operons that are cotranscribed and autoregulated, in a manner unlike typical TA modules.

134 The expression of dnaA is autoregulated, in that transcription of the gene increas

135 Here we demonstrate that this autoregulated instability controls the abundance of endo

136 We propose that kinase-mediated, autoregulated instability of Plk4 self-limits Plk4 activ

137 contains a kinase domain that is thought to autoregulate its activity.

138 a mechanism to explain how bFGF functions to autoregulate its expression and demonstrate that Egr-1 i

139 wn transcripts, and one of these is known to autoregulate its expression by coupling alternative spli

140 Phd has been shown to autoregulate its expression by specific DNA binding.

141 ets-5 may also autoregulate its expression in BAG neurons.

142 present study, we show that PTEN is able to autoregulate its expression through the stabilization of

143 t ELAV binds to the 3' UTR of its own RNA to autoregulate its expression.

144 consistent with wild-type p53 being able to autoregulate its levels by down-regulating expression of

145 Thus, TNF-alpha can positively autoregulate its own biosynthesis in adipose tissue, con

146 HJ50 and acts as the extracellular signal to autoregulate its own biosynthesis through BovK/R two-com

147 allowing maturation factor p63 to positively autoregulate its own expression and close a subset of th

148 es within the ZTA promoter and to positively autoregulate its own expression in transient cotransfect

149 Thus, Nrf2 appears to autoregulate its own expression through an ARE-like elem

150 lay signal transduction system and that MrpC autoregulate its own expression.

151 inhibitor SOCS-3 acts in a negative loop to autoregulate its own gene expression, thus limiting its

152 Thus, RPL-12 appears to autoregulate its own splicing, with unproductively splic

153 These results indicate that QseB may act to autoregulate its own transcription through binding to lo

154 enhances the ability of this ribonuclease to autoregulate its synthesis in E. coli.

155 in (TA) module, binds to its own promoter to autoregulate its transcription: repress or induce transc

156 a phytopathogenic bacterium that appears to autoregulate its virulence genes, produces compounds tha

157 atRA autoregulated its concentrations by inducing retinyl est

158 RTA also autoregulated its own polyubiquitination and stability,

159 We present evidence that TBP negatively autoregulates its accessibility to promoter DNA in yeast

160 growth factors and nutrients, but how mTORC1 autoregulates its activity remains unclear.

161 Here, we report that NSP2 autoregulates its chaperone activity through its C-termi

162 liferation/differentiation through STAT6 and autoregulates its effects on Th2 growth and effector fun

163 inds to this element, suggesting that LIN-39 autoregulates its expression in P6.p.

164 To define mechanism by which HOXA9 autoregulates its expression, we show that HOXA9 DNA bin

165 kinase-dead mutant, we established that Mnk1 autoregulates its interaction with eIF4G, releasing itse

166 sigma(MibX) autoregulates its own expression but does not directly r

167 described role as a splicing activator, Nova autoregulates its own expression by acting as a splicing

168 ccharomyces cerevisiae ribosomal protein L30 autoregulates its own expression by binding to a purine-

169 how that RstR both positively and negatively autoregulates its own expression from this promoter.

170 We showed recently that B-Myb autoregulates its own expression through promoter transa

171 d previously published data that blimp1/krox autoregulates its own expression, but discovered, surpri

172 edn1-dependent manner, suggesting that edn1 autoregulates its own expression.

173 xpression from the melR promoter; thus, MelR autoregulates its own expression.

174 cifically to DNA in its target promoters and autoregulates its own expression.

175 We also have found that Loz1 negatively autoregulates its own expression.

176 l-fusion reporter assays indicated that CovR autoregulates its own expression; this was verified by t

177 gulatory system that senses ferrous iron and autoregulates its own operon.

178 The human U1 snRNP-specific U1A protein autoregulates its own production by binding to and inhib

179 -kDa alternative sigma factor (sigma22) that autoregulates its own promoter (PalgT) as well as the pr

180 lR protein is a transcription activator that autoregulates its own promoter by repressing transcripti

181 pi autoregulates its own synthesis and is required for repl

182 onas aeruginosa toxA regulatory protein PtxS autoregulates its own synthesis by binding to a 52-bp fr

183 the accumulation of the SPT protein, and SPT autoregulates its own transcript abundance in conjunctio

184 sion, ChIP, and co-IP studies show that SCL3 autoregulates its own transcription by directly interact

185 ore, we provide evidence that GIV positively autoregulates its own transcription by enhancing STAT3 a

186 rR expression and found that SgrR negatively autoregulates its own transcription in the presence and

187 The results suggest that glucose autoregulates its own transport into skeletal muscle by

188 The cellular mitochondrial collective autoregulates its population through biogenic renewal an

189 RNase E autoregulates its production in Escherichia coli by gove

190 Dlx2 autoregulates its promoter, and Dlx2 transcriptionally a

191 These results suggest that PtxS autoregulates its synthesis by binding to a specific seq

192 Lastly, we found that TDP-43 autoregulates its synthesis, in part by directly binding

193 iated from the Qa promoter in prgQ, and PrgX autoregulates its transcription either by mediating tran

194 co transcription unit, suggesting that Disco autoregulates its transcription in the optic lobe primor

195 rferi BpuR protein binds to its own mRNA and autoregulates its translation, and also serves as co-rep

196 The YpsRI system negatively autoregulates itself but positively regulates the expres

197 The KorB protein also autoregulates korB gene expression and may be involved i

198 s these enzymes and produce prostanoids that autoregulate maturation and IL-12 production.

199 ts upstream cre were not required for normal autoregulated mga expression from Pmga P2 as long as Mga

200 ive Pmga resulted in a dramatic reduction in autoregulated mga expression in both mutant strains.

201 t Srsf10 expression is controlled through an autoregulated minor intron, tightly correlating Srsf10 w

202 in G may play a central role in the p53-Mdm2 autoregulated module, but the precise function of cyclin

203 It constitutes a minimal autoregulated multidrug resistance system against numero

204 e Drosophila homolog of hoxc-4, Deformed, is autoregulated, mutation of the hoxc-4 gene does not affe

205 The autoregulated nature of the K. pneumoniae fur gene and f

206 ression of Pax3 itself (suggesting that Pax3 autoregulates), neuronal differentiation and delaminatio

207 mational plasticity provides a mechanism for autoregulating NS1 functions, depending on its temporal

208 of the chrAS operon revealed that it was not autoregulated or affected by iron or heme levels.

209 We propose that PARP-e autoregulates Parp transcription by influencing the chro

210 In 11 autoregulating preparations, proximal transit time was l

211 PrgX positively autoregulates production of both itself and mature Qa RN

212 titutive basal-level expression and a second autoregulated promoter for induced expression.

213 capacity of TCSs, a high TF affinity for the autoregulated promoter or a low fold change in signaling

214 The gene is preceded by a single autoregulated promoter whose -10 region overlaps the put

215 We programmed protein expression cycles, autoregulated protein levels, and a signaling expression

216 ber bacterial plasmids, typically encode two autoregulated proteins and an adjacent cis-acting centro

217 in beta(2)AR signalling, observing that ICL3 autoregulates receptor activity through a dynamic confor

218 our data suggest that ainS transcription is autoregulated, resulting in an over 2,000-fold increase

219 tivate the transcription of two operons: the autoregulated sigV-rsiV-oatA-yrhK operon and dltABCDE.

220 lular level of wild-type PrrA was negatively autoregulated so that less PrrA was present in the absen

221 that are mechanistically distinct; and it is autoregulating so as to maintain intracellular iron home

222 plicing regulator by studies showing that it autoregulates splicing of its own pre-mRNA.

223 eals a heretofore unrecognized mechanism for autoregulating SQOR by H(2)S on demand.

224 affected by the growth substrate and was not autoregulated, suggesting that binding of SusR to maltos

225 nism of oscillatory or pulsatile dynamics in autoregulated TCSs.

226 hese data demonstrate that B-Raf activity is autoregulated, that constitutive phosphorylation of Ser(

227 most closely related PTPs (PTP1B and TCPTP) autoregulate the activity of their cognate PTPs via comp

228 Does ROS production autoregulate the excitability of a neuron?

229 rovides a positive and negative mechanism to autoregulate the expression of REB1.

230 one proteins, indicating that histones might autoregulate the histone mRNA half-life.

231 nstitutively activates the Notch1 pathway to autoregulate the LMP2A promoter.

232 The Q548R RV is able to negatively autoregulate the MIE promoter, transactivate viral early

233 es the parA promoter region where it acts to autoregulate the P1 parA-parB operon.

234 equires the product of another gene, snf, to autoregulate the splicing of its own transcripts.

235 longed membrane depolarization, inactivation autoregulates the activity of voltage-gated ion channels

236 Thus, conventional PKC autoregulates the carboxy-terminal phosphorylation switc

237 ults suggest that B. pertussis is capable of autoregulating the activity of the bvg regulon through i

238 ls to adapt to the hyperosmotic milieu while autoregulating the expression of molecules that generate

239 isite intrinsic mechanisms the heart has for autoregulating the force of contraction to maintain card

240 assembly and disassembly processes, thereby autoregulating the interaction of MDA5 with dsRNA, and p

241 h of the mammary epithelial cell line and in autoregulating the powerful internal growth-inhibiting d

242 toxin-antitoxin (TA) pairs transcriptionally autoregulate their expression via a repression/derepress

243 onstitutively and produce prostanoids, which autoregulate their maturation and function.

244 These compounds autoregulate their metabolic fate by end-product repress

245 h GAG and aggrecan synthesis, disc cells can autoregulate their osmotic environment and accommodate m

246 Furthermore, both Mitf and Otx2 can autoregulate their own enhancers in vitro.

247 Hes/Her proteins form dimers and negatively autoregulate their own transcription.

248 nd timeless genes oscillate and the proteins autoregulate their transcription.

249 the flexible C-tail region of these factors autoregulates their DNA binding activity.

250 Because DnaA is autoregulated, these results might be due to the inhibit

251 ry initiator of its own expression, which is autoregulated through a novel FGF2-PI3K-Akt loop.

252 Expression of Ire1p mRNA was autoregulated through a process that required a function

253 Transcription of rho is autoregulated through a Rho-dependent attenuation in the

254 Polyamines are autoregulated through induction of antizyme, which repre

255 egulatory elements and that it is negatively autoregulated through two EBNA-1 binding sites downstrea

256 In addition, Zp is autoregulated through two sites that bind the BZLF1 gene

257 es Mps1 kinetochore retention, suggesting an autoregulated, timer-like mechanism.

258 y initiating expression of odr-7, which then autoregulates to maintain expression.

259 7A mutant IE86 protein is able to negatively autoregulate transcription from the major immediate-earl

260 the requirement for high fold change of the autoregulated transcription but demands high phosphoryla

261 The copper-responsive repressor CsoR autoregulates transcription by binding to a single 32 bp

262 tifs are activated in postmitotic neurons by autoregulating transcription factors (TFs).

263 t bFGF leads to its own synthesis through an autoregulated transcriptional response that requires the

264 ono-/bistable parameter range for positively autoregulated two-component systems (TCSs) in the presen

265 hrough the exact stochastic simulation of an autoregulated two-gene cascade operating near instabilit

266 Transcription of dksA was negatively autoregulated via a feedback loop that tended to mask Cs

267 ional analyses of PknK revealed that PknK is autoregulated via intramolecular interactions with its C

268 Here, we uncover that RBM39 autoregulates via the inclusion of a poison exon into it

269 established that the response regulator was autoregulating via direct binding.

270 hat different classes of viral ncRNAs act to autoregulate viral gene expression and evade host antivi

271 ugh specific viral miRNAs have been shown to autoregulate viral mRNAs or downregulate cellular mRNAs,

272 ting that it is an intercellular signal that autoregulates virulence gene expression in wild-type R.

273 TFs that autoregulate were highly conserved between tissues.

274 ts show that Lmx1 promotes proliferation and autoregulates, whereas Cdkn1b limits proliferation and i

275 ly, the codY gene was shown to be negatively autoregulated, with its protein binding directly to the

276 low than their axons; ganglion blood flow is autoregulated within the range of blood pressure tested.