ライフサイエンスコーパス: avenue

1 ial leptin reduction as a viable therapeutic avenue.

2 spiratory system, as well as new therapeutic avenues.

3 iology of disease might open new therapeutic avenues.

4 AF is needed to spearhead novel therapeutic avenues.

5 ient populations could offer new therapeutic avenues.

6 ivery is a relatively under-studied research avenue and is discussed with reference to existing techn

7 Throughout, I propose research avenues and approaches to assess how sensory drive shape

8 source economy in molecular syntheses, novel avenues are required, which include, but are not limited

9 e have so many materials opens many exciting avenues but also create new challenges.

10 inally, we explore potential future research avenues, emphasizing the integration of microevolutionar

11 This work could open an avenue for achieving long cycle life and high-power lith

12 ssful phase I trial also provides a possible avenue for achieving transplantation without the requisi

13 ally compliant adsorbent, offers a promising avenue for addressing some of the most challenging gas s

14 tmortem studies are a particularly important avenue for advancing our understanding of the pathogenes

15 This synthetic route opens a new avenue for an expeditious assembly of various isotryptam

16 , dispersion is being considered a promising avenue for biofilm control.

17 as obtained thus demonstrating its promising avenue for cancer monitoring based on liquid biopsy.

18 nhibition of microRNAs (miRNAs) offers a new avenue for cancer therapeutics.

19 (MALAT1) has been proposed as an attractive avenue for cancer treatment and a model system for under

20 tic bystander genetic events represent a new avenue for cancer treatment.

21 SPHK1 axis serves as a potential therapeutic avenue for ccRCC.

22 fabrication process described provides a new avenue for composite material synthesis, while the uniqu

23 This development provides a new avenue for constructing Csp(3)-Csp(3) bonds.

24 tense emission would certainly provide a new avenue for continuing their further research.

25 link between bile acids and PTB, and open an avenue for developing etiology-based therapies to preven

26 This work can provide a new avenue for developing potassium metal-based batteries.

27 nephrin in R218Q knockin podocytes opens an avenue for developing targeted therapy for INF2-mediated

28 This approach could be a promising avenue for development of BCI-based solutions for fast c

29 A promising avenue for disease control involves leveraging innate ho

30 ified oligonucleotides represent a promising avenue for drug development, with small interfering RNAs

31 Topological materials offer a new avenue for energy harvesting applications.

32 e in PCa, potentially offering a therapeutic avenue for enhancing the efficacy of enzalutamide to bet

33 f skill over LIM approaches, thus opening an avenue for environmental risk assessment relevant in a v

34 an previously demonstrated and open up a new avenue for experimental investigation within layers of o

35 hrough-promoting compounds are a therapeutic avenue for familial FTD caused by progranulin PTC mutati

36 and apoptosis, and provide a new therapeutic avenue for fracture healing.

37 of genome-wide association data provides an avenue for further understanding the prevalence and role

38 The developed approach provides an avenue for future investigations surrounding fundamental

39 lex, hierarchical environments and opens the avenue for future research in this field.

40 s the optic nerve head and may provide a new avenue for glaucoma therapy.

41 mmune checkpoint inhibition as a therapeutic avenue for HNFS angiosarcoma.

42 +/LY6D+ nMRTF human BCCs ex vivo, opening an avenue for improving combinatorial therapies.

43 the module and matrix regions, providing an avenue for integration of information across compartment

44 tion, which provides a potential therapeutic avenue for KSHV-associated cancers.

45 l fates may represent a possible therapeutic avenue for MEN-associated neoplasms.

46 respiration may constitute a surprising new avenue for PD treatment.

47 se UDCA-HDAC6i conjugates open a therapeutic avenue for PLDs.

48 The current work paves a new avenue for precise control of single-atom sites on carbo

49 ng PME-1 may constitute a viable therapeutic avenue for preventing Abeta-related impairments in Alzhe

50 de antibodies and cytokines could provide an avenue for reducing the clinical toxicity associated wit

51 xacerbate intergroup conflict and provide an avenue for reducing the negative effects of inaccuracy.

52 rigorously in unrestrained mice opens a rich avenue for research into neural circuit mechanisms under

53 lieve the presented approach will pave a new avenue for scalable production of advanced mesoporous ma

54 n of an electrocatalyst presents a promising avenue for solar fuels synthesis from carbon dioxide (CO

55 This discovery provides a new avenue for stabilizing mixed ionic-electronic conduction

56 This approach opens a powerful avenue for studying, at the single particle level, catal

57 d store information and thus present a novel avenue for synaptic regulation with limited direct inter

58 s beyond standard kinetics and suggest a new avenue for tailoring selective adsorption by thermally t

59 ay in chordoma and suggest it as a promising avenue for targeted therapy.

60 criptive Bayesianism offers a more promising avenue for the development of a Bayesian theory of cultu

61 n and synthesis of isoindigo 4-7 gives a new avenue for the development of building blocks in organic

62 This work opens a new avenue for the development of high-efficiency catalysts

63 enous channel-opening lipids and opens up an avenue for the development of ion-channel modulators.

64 ntigen engineering outlined here provides an avenue for the development of preventive HCV vaccine can

65 ose used by insect navigators, opening a new avenue for the investigation of the neural basis of navi

66 sider O-PTIR spectromicroscopy to open a new avenue for the nondestructive, efficient, and reliable a

67 derstudied route of infection and open a new avenue for the pathogenesis of B. pseudomallei.

68 ocrystals available, our findings open a new avenue for the synthesis of functional and tunable polye

69 Our discoveries open a new avenue for the treatment and prevention of repeat expans

70 agonist, such as ICT12035, can provide a new avenue for the treatment of cancers.

71 SphK1 inhibitors might be a new therapeutic avenue for the treatment of type I IFN-linked autoimmune

72 r types, the SENP3-E2F1 axis may serve as an avenue for therapeutic intervention in cancer.

73 y, suggesting an indirect stromally targeted avenue for therapy resensitization.See related article b

74 4BP4 in the liver may be a novel therapeutic avenue for treating NAFLD.

75 3 agonistic treatment as a novel therapeutic avenue for treating T2DM.

76 thermomechanical processing, providing a new avenue for tuning the mechanical properties of medium- a

77 with those who are obesity prone provides an avenue for unraveling the difficulties people with obesi

78 synthetic approach opens up an entirely new avenue for utilizing PQDs in aqueous environment, which

79 cations, yet require fundamentally different avenues for accommodating plastic deformation in the bod

80 ignatures and, most significantly, opens new avenues for accurate diagnosis and clinical assessment i

81 The success of these new methods opens avenues for AIT to be more widely used.

82 agy dependent disease phenotypes and provide avenues for alternative therapeutic approaches.

83 with a variety of appearances and enable new avenues for automation of fluorescence microscopy acquis

84 y cilia/Hh signaling could not only open new avenues for cancer therapeutic discovery but could also

85 rough a class of allosteric inhibitors opens avenues for cancer therapy.

86 Our results open avenues for compact time-domain, on-chip CEP detection,

87 addressing gaps in kidney care; and outlines avenues for conducting research, leveraging this nationa

88 The identification of POP opens up numerous avenues for continued scientific exploration, including

89 chiometric MXenes reported to date and opens avenues for controlling physical properties of different

90 entially opening new prevention or treatment avenues for depression and its associated cardiometaboli

91 -enabled strategy is expected to provide new avenues for designing a range of meso-MPN particles for

92 ion and stabilisation, and open up promising avenues for designing bio-reinforced geo-materials that

93 teractive behaviors can be obtained, opening avenues for designing multifunctional materials.

94 This work opens new avenues for diagnosis and treatment of multidrug resista

95 a pharmacological approaches, this opens new avenues for diagnostic and therapeutic approaches.

96 l development and diseases, could unlock new avenues for discovery of modulators of FGF signalling th

97 reviewing this research and offering future avenues for discovery, we hope that others also embrace

98 chnology-based smart sensors are opening new avenues for early and rapid detection of such pathogens

99 We have thus developed avenues for engineering the surface of nanoparticles for

100 on crystal growth inhibitors, that opens new avenues for evaluating drug dosing regimens and understa

101 tative, intraspecific approach generates new avenues for evaluating fitness consequences of FLS varia

102 This study opens avenues for expanding plant chemodiversity through halog

103 Thus, we have identified several avenues for experimental approaches whose aim is to redu

104 ubset of which have unknown function opening avenues for exploration.

105 Our results thus open new avenues for exploring fundamental phenomena and novel op

106 s may impact biocontrol programs and suggest avenues for further integration of natural enemy ecology

107 Our work opens new avenues for further investigation of the role of this fu

108 g, while identifying current limitations and avenues for future development in sensor technology.

109 Our findings open up avenues for future investigation as to what roles FRZB a

110 Implications and potential avenues for future research and translation are discusse

111 difficulties in children, our findings open avenues for future research in human and animals.

112 elin dysregulation, and we identify critical avenues for future research in this regard.

113 conclude by suggesting potentially fruitful avenues for future research.

114 Finally, we end by highlighting avenues for future research.

115 linear models and suggests several promising avenues for future research.

116 tween these processes also provides exciting avenues for future research.

117 current knowledge gaps and proposes several avenues for future scientific exploration in order to de

118 ng of regional PDL function, which opens new avenues for future studies of remodeling, regeneration,

119 phagocytosis, and synaptic pruning, creating avenues for future studies on the importance of PTEN in

120 Finally, we suggest promising avenues for future work in this rapidly expanding field.

121 platform with unique properties, opening new avenues for highly integrated sensing devices with real-

122 ates are tools that may open new therapeutic avenues for I(2)-IR, particularly for unmet neurodegener

123 ng oncogenic BRAF mutations and provides new avenues for improved RAF-inhibitor discovery.

124 ance in regulation of excitability opens new avenues for improved therapy for muscle channelopathies

125 clude with a discussion of several potential avenues for improvement.

126 Potential avenues for improving bioplastic properties to broaden t

127 They also suggest new avenues for improving influenza control.

128 nces in cancer screening methods have opened avenues for incidental findings and cancer overdiagnosis

129 The discovery that PGs have NIRAF led to new avenues for intraoperatively identifying PGs with high a

130 g method we optimized for single cells opens avenues for investigating low-frequency mutations in oth

131 anodomains in unperturbed membranes open new avenues for investigation of nanoscopic membrane organiz

132 complication of diabetes should open up new avenues for investigation that may ultimately improve th

133 lished at room temperature; hence this opens avenues for magnetooptical memory devices.

134 evolution and could help advance therapeutic avenues for managing pathological conditions, such as di

135 tive manufacturing currently facilitates new avenues for materials discovery that have not been fully

136 atic cell state in lung cancer and opens new avenues for metastasis-specific therapeutic targeting.

137 alkylfurans in food, and ultimately opening avenues for mitigation.

138 sly intractable resolution and offers up new avenues for modeling and visualizing higher order chroma

139 uced in vitro from iPSC, opening interesting avenues for muscular dystrophy cell therapy.

140 nities via network structure, and we suggest avenues for new theoretical work to strengthen these con

141 gression, and that targeting SEMA7A may open avenues for novel therapeutic strategies.

142 g of how to modulate mitophagy could provide avenues for numerous therapies.

143 Our findings open new avenues for organic solar cell design where material ene

144 tive studies, evolutionary studies and opens avenues for pathogen discovery.

145 Thus, RvD6si opens up new therapeutic avenues for pathologies that affect corneal innervation.

146 itonin signalling thus may offer therapeutic avenues for patients with atrial fibrillation.

147 rgy and size, and their outliers provide new avenues for physiological and ecological research.

148 Targeting this pathway has also identified avenues for potential expansion into several other indic

149 It also opens new avenues for precision medicine- diagnostics (assement of

150 signaling is encoded or decoded may open new avenues for rational pharmacological targeting of PI3K-a

151 t how these insights have informed potential avenues for rational therapeutic interventions.

152 ty profiles for a number of CDKi's, offering avenues for repurposing of highly potent molecules as pr

153 prospective memory, mind-wandering), and new avenues for research in this area are outlined.

154 rocesses in filamentous fungi, and opens new avenues for research on the morphogenesis of filamentous

155 alls of these approaches, as well as further avenues for research.

156 The method we describe opens new avenues for studies focusing on yeast cells, as well as

157 amic mode of Y chromosome evolution and open avenues for studies of male-specific dispersal in endang

158 XPSCs open new avenues for studying mammalian pluripotency and dissecti

159 n from ATP hydrolysis, which may provide new avenues for studying the catalytic mechanism of nitrogen

160 ue morphogenesis using time series opens new avenues for systematic decomposition of tissue morphogen

161 nsic rheostat of Th17 immunity, and open new avenues for T cell-based therapies for Nod2-associated d

162 These findings open newer avenues for targeted drug therapies, thereby providing h

163 protein kinase superfamily and may open new avenues for targeting human FN3K in diabetic complicatio

164 nation of HDX with native MS opens promising avenues for the analysis of the structural and biophysic

165 These results suggest potential new avenues for the application of LRRK2 inhibitors in demye

166 rstanding of the parasite's biology, opening avenues for the development of therapeutic intervention

167 The proposed device can open new avenues for the fascinating applications of next-generat

168 Our results open avenues for the field of non-Hermitian topology and for

169 n polymerization strategies and presents new avenues for the generation of functional metathesis mate

170 These and other advances have opened new avenues for the medicinal chemistry of PS-ASOs and resea

171 This phenotypic assay opens new avenues for the precise characterization of the mechanis

172 est that targeting inflammation may open new avenues for the prevention and the treatment for cardiov

173 anistic insights offer potential therapeutic avenues for the prevention and/or improved treatment of

174 implicated in AF substrate and suggest novel avenues for the prevention or therapy of this common arr

175 These results open new avenues for the study and treatment of retinal vascular

176 nt-initiation and -cancellation, opening new avenues for the study of motor control in health and dis

177 ression or activity in NSCLC may provide new avenues for the therapeutic treatment of lung cancer.

178 o understand the pathogenesis and create new avenues for the treatment of mood disorders.

179 their phenotype, may lead to new therapeutic avenues for the treatment of radiation-induced lung inju

180 rgets for CM adjunctive therapy, opening new avenues for the treatment of this deadly disease.FUNDING

181 The conclusions of this work open new avenues for the understanding of crystal growth, as well

182 h stage of vascular remodeling will open new avenues for therapeutic advancements in the treatment of

183 This opens up future avenues for therapeutic modulation of redox status in IB

184 ppression of metastasis and highlighting new avenues for therapy against metastatic disease.

185 ect of HF on the gut microbiome suggests new avenues for treating GWI through dietary intervention.

186 derstanding of disease and may provide novel avenues for treatment development.

187 r circuit components in vivo, RdLight1 opens avenues for understanding many aspects of dopamine biolo

188 ization and activity and highlight potential avenues for understanding mechanisms controlling the div

189 9, indicating that metabolomics may open new avenues for understanding the pathophysiology of this di

190 epends on the specific mechanism and suggest avenues for work at the molecular, neuronal, and systems

191 However, this avenue has not been explored in the case of 2D materials

192 NF-YB21-FUS3-NCED3 functions as an important avenue in auxin-regulated poplar root growth in response

193 ng lipid metabolism may be a new therapeutic avenue in ccRCC.

194 P-eIF2alpha/Gadd34 complex as a therapeutic avenue in CMT1B and also suggest that PERK may hamper my

195 ollectively, our results open novel research avenues in deadly tumors.

196 individual self-propelled units may open new avenues in designing of materials from within.

197 This approach has opened up new avenues in drug design and development resulting in more

198 ways and psbA gene expression could open new avenues in engineering programs of cyanobacterial strain

199 PULSE opens broad experimental avenues in plant research and biotechnology.

200 ain group elements in catalysis, opening new avenues in synthetic chemistry.

201 investigated in the near future, open up new avenues in the field of ionic gold and gold nanoparticle

202 utlook over future efforts and promising new avenues in this field.

203 These findings open new research avenues into the biological mechanisms that underlie ind

204 However, a more exciting avenue is the detection of certain biomarkers associated

205 Another important research avenue is the study of chrono-medical timing of sleep de

206 n of sphingolipids may represent a promising avenue of therapeutic development for childhood asthma.

207 nd that HIF-1alpha blockade could be a novel avenue of treatment for these tumors.

208 Finally, we propose future avenues of clinical investigation and potential therapeu

209 consistently revealed previously unforeseen avenues of clinical therapies.

210 ilateral affective touch perception open new avenues of enquiry regarding the cortical organization o

211 r findings also provide a foundation for new avenues of inquiry into GI stem cell biology and of OSTE

212 before the diagnosis of motor PD, suggesting avenues of investigation into PD pathogenesis and potent

213 ve had in these discoveries, and outline new avenues of investigation to continue moving the field fo

214 utics may be developed into promising future avenues of precision treatment.

215 ease and offer opportunities to identify new avenues of research and novel targets for treatment.

216 sents an important first step in opening new avenues of research by leveraging the power of modern-te

217 This method will enable new avenues of research into plant sexual reproduction.

218 Moreover, our work highlights further avenues of research regarding the nature and function of

219 previously associated with W, suggesting new avenues of research.

220 ealth interventions; and fostering promising avenues of research.

221 ent of new IDAs and suggest potential future avenues of research.

222 into frameworks of memory function opens new avenues of study and even therapies for hippocampal dysf

223 ral pH is anticipated to enable new research avenues, particularly for applications in biological med

224 Overall, the results demonstrate a new avenue that is ready to use for large-scale cryo-EM-base

225 e the size of the latent HIV reservoir is an avenue that should be explored.IMPORTANCE As part of thi

226 y a more specific focus on novel therapeutic avenues that are entering the clinic and may replace IVI

227 sociated microbiota would potentially reveal avenues that can be exploited for clinical benefit.

228 n the RV-Cs and their receptors provides new avenues that can be explored for potential antiviral the

229 Lastly, the therapeutic avenues that either target the microbiota, the barrier s

230 omplications and highlight novel therapeutic avenues that may be exploited to target senescent cells

231 -2, highlighting potential novel therapeutic avenues that were validated by a high hit rate in a targ

232 ety of substrates, thus bestowing a powerful avenue to access tri- and tetrasubstituted pyridines inc

233 The results demonstrate a new avenue to accurately detect domain composition from sequ

234 ecting a wide range of hosts, offer a useful avenue to address this question.

235 t-structure-specific DNA ligands are a novel avenue to contract expanded repeats.

236 COFs with designable functions and opens an avenue to create COFs as multifunctional systems.

237 for water purification and opens up a simple avenue to creating 2D membranes through molecular self-a

238 and single nucleus RNA profiling provide one avenue to decipher this heterogeneity.

239 This axis may represent a new avenue to design effective therapeutics based on tumor s

240 framework metal node, portending a potential avenue to develop an alternative to natural biomarkers.

241 Our work opens an avenue to develop functional MOF channels for selective

242 embrane regulators and highlight a potential avenue to develop new GABA(A)R psychopharmacology by tar

243 tible isomers of the nanoclusters open up an avenue to employ ultra-small nanoclusters (1 nm) for the

244 The results open up a new avenue to engineer memristors for desired properties.

245 Borromean linked organic polymers paves the avenue to expand the supramolecular-synthon-driven appro

246 sChoK inhibition is a promising avenue to follow in the development of therapeutics for

247 without any apparent frustration, the common avenue to generate spiral arrangements in multiferroics.

248 ethyltransferase inhibitors provides another avenue to halt the exacerbation of the inflammatory resp

249 on local structural dynamics may open a new avenue to implement DW nano-devices for radio-frequency

250 rough large-scale HCP deletion, providing an avenue to increased quality and affordability of high-va

251 Our approach presents a promising avenue to integrate experimental data and make regional-

252 pe glycosylation on each site provides a new avenue to investigate the function of glycoproteins in b

253 cells (iPSCs) of the patients are a powerful avenue to investigate the pathophysiological processes.

254 location of the blocker, provides a powerful avenue to investigate the selectivity of the binding sit

255 hese tools provide an exciting translational avenue to merge omics-based drug discovery platforms wit

256 duction of carbon dioxide offers a promising avenue to produce valuable fuels and chemicals using gre

257 Our findings show there is a viable avenue to room-temperature aqueous-phase formation of Cd

258 to specific protein scaffolds, opening a new avenue to study localized kinase activity.

259 urement methodology presented provides a new avenue to study materials behaviour in extreme environme

260 ization through this pathway, and open a new avenue to study the interplay among endocytosis, metabol

261 The simple task design thus provides an avenue to studying surprise as a pure form of reactive i

262 on profiles in blood may present a promising avenue to support clinical decision making by providing

263 ese results reveal a previously unrecognized avenue to target HIPK2 in neuroprotection via the Parkin

264 The work offers a further avenue to utilize MOFs in the pursuit of materials desig

265 cholinergic activity will open critical new avenues to a better understanding of ACh in the brain.Du

266 ezing by age 3 years, possibly providing new avenues to ameliorate the long-term respiratory outcomes

267 often suggest protein functions and open new avenues to characterize genes and proteins.

268 eting ILC2 in the aged brain may provide new avenues to combat aging-associated neurodegenerative dis

269 pockets in liquid water, which suggests new avenues to control guest complexation.

270 These ageotypes open new avenues to creating diagnostic and treatment strategies

271 ISR can be modulated promises to uncover new avenues to diminish pathologies resulting from it for cl

272 The work described here provides new avenues to disease altering therapeutic interventions in

273 natural variation of silencing, and provides avenues to dissect broader evolutionary changes at FLC.

274 This information reveals promising avenues to engineer guide RNAs for enhanced CRISPR-Cas f

275 short palindromic repeats)-have opened novel avenues to experimentally identify biologically signific

276 yeast complementation pairs, thus opening up avenues to further functionally characterize these human

277 eted anticancer agents and explore potential avenues to harness them in support of superior clinical

278 s studies (Marvi et al., 2014) and indicates avenues to improve all-terrain robots.

279 ctive response to Mtb infection and possible avenues to interfere with Mtb infection, including vitam

280 rved in vivo properties of ParB and opens up avenues to investigate the interactions between ParB-par

281 ent challenges in COF design and open up new avenues to new real-world applications of COFs.

282 p provides an initial framework for creating avenues to overcome the drug resistance of ferroptosis a

283 target evolutionary dynamics may offer novel avenues to slow the spread of antibiotic resistance.

284 he distal lung, thereby opening numerous new avenues to study lung development, infection, and regene

285 tissues, cells, and organelles opens up new avenues to target metabolic regulators locally rather th

286 y of translation initiation by OCM opens new avenues to understand alternative translation mechanisms

287 ron and plant protection and opens promising avenues to use siderophore-mediated interactions as a to

288 ridged dinuclear cobalt compounds provide an avenue toward controlled two-step VT interconversions of

289 electrochemical nanocrystal scrambling is an avenue toward creating such catalysts.

290 ng stoichiometry represents an underexplored avenue toward developing receptors that can differentiat

291 near the Fermi energy remains an intriguing avenue toward engineering the properties of quantum mate

292 electrical stimulation, can be an appealing avenue toward functional restoration of injured nervous

293 accessibility of Fe-N(x) species paves a new avenue toward high-performance ORR electrocatalysts.

294 ogress into a historical context and provide avenues toward a more comprehensive understanding of sol

295 he single-molecule level, but also opens new avenues toward advanced deeper understanding of enzymes,

296 d hydrolytic enzymes reported here opens new avenues toward the development of efficient catalysts fo

297 This approach opens avenues toward the synthesis of encapsulated carbon allo

298 ence of superconductivity in TBG and open up avenues towards engineering quantum phases in moire syst

299 a potential biomarker opens up new research avenues which may finally lead to a better understanding

300 old(III) has revealed unexpected mechanistic avenues, which can open when the barriers for reactions