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1 ts to be a target of the antiparasitic agent avermectin.
2  channel that is gated by both glutamate and avermectin.
3 of potentiation of the glutamate response by avermectin.
4 -chain acid starter units typical of natural avermectins.
5 abamectin and emamectin benzoate-both potent avermectins-abolished spontaneous activity in the absenc
6                             In contrast, the avermectins activate both ligand- and voltage-gated chlo
7     Doramectin is a commercial antiparasitic avermectin analog produced by fermenting a bkd mutant of
8 l Committee described as 'The discoveries of Avermectin and Artemisinin have revolutionized therapy f
9                                              Avermectin and beta-cypermethrin are commonly used insec
10 observed in C. elegans GluCl: dual gating by avermectin and glutamate, a rapidly desensitizing glutam
11 encoding chloride channels that are gated by avermectin and glutamate, respectively, were isolated fr
12 ::Tc1 strain mRNA elicited reduced amplitude avermectin and glutamate-dependent chloride currents.
13 shi Omura for their role in the discovery of avermectin and Professor Youyou Tu for her work on the d
14                                Erythromycin, avermectin and rapamycin are clinically useful polyketid
15 eric channels that are gated irreversibly by avermectin and reversibly by glutamate.
16 ents suggest that GluClalpha is a target for avermectin and that additional glutamate-gated and averm
17 hi Omura, and Youyou Tu for the discovery of avermectins and artemisinin, respectively, therapies tha
18 armaceutically important polyketides such as avermectin are mainly produced as secondary metabolites
19                                              Avermectins are a class of macrocyclic lactones that is
20 , but genes conferring natural resistance to avermectins are unknown.
21   The method is suitable for the analysis of avermectins at concentration as low as 2.5 mug kg(-1), a
22    Ivermectin, a semisynthetic derivative of avermectin B(1), is among the efficacious drugs used in
23  Application of ddTAG increased the titer of avermectin B(1a) by 50% to 9.31 g l(-1) in a 180-m(3) in
24 tinorhodin, jadomycin B, oxytetracycline and avermectin B(1a) in Streptomyces coelicolor, Streptomyce
25 cyclopentylmethyl radical on the skeleton of avermectin B1 has been investigated using density functi
26 OB binding, including midazolam, flurazepam, avermectin Ba1, baclofen, isoguvacine, and propofol, at
27                                              Avermectin binding assays in GluClalpha::Tc1 strain memb
28                In addition, the detection of avermectins by high resolution mass spectrometry using a
29 annel subunits that represent targets of the avermectin class of antiparasitic compounds, have recent
30 target site involvement in resistance to the avermectin class of compounds.
31 d H-receptor and an important target for the avermectin class of insecticides.
32                                          The avermectin derivative emamectin benzoate (EMB) has been
33 e (a butenolide) regulates the production of avermectin, derivatives of which are used in the treatme
34    We present a simple method for extracting avermectines from meat, based on a QuEChERS approach fol
35 ible for the production of the anthelminthic avermectins, harbors a 13.4 kb gene cluster containing 1
36 stance of nematodes to anthelmintics such as avermectins has emerged as a major global health and agr
37 ated chloride channel, confers resistance to avermectins in the model nematode Caenorhabditis elegans
38 he spiroketal moiety present in anthelmintic avermectins isolated from actinomycete bacteria.
39                     Following application of avermectin or beta-cypermethrin, F. occidentalis became
40                                  Because the avermectin polyketide synthase is known to accept more t
41 t the same variant confers resistance to the avermectin-producing bacterium Streptomyces avermitilis.
42  The wide-specificity loading module for the avermectin-producing polyketide synthase was grafted ont
43 lated to the alpha-subunit of the C. elegans avermectin receptor.
44 tion in glutamate-gated chloride channels in avermectin resistance and provide a mechanism by which s
45 ctin and that additional glutamate-gated and avermectin-sensitive chloride channel subunits exist in
46 udy the role of these subunits in conferring avermectin sensitivity we isolated a mutant C. elegans s
47 exhibit a normal phenotype including typical avermectin sensitivity.
48 zone), the glutamate-gated chloride channel (avermectins), the octopamine receptor (amitraz metabolit
49 the insecticides chlorpyrifos, clothianidin, avermectin, thiamethoxam, and imidacloprid.