ライフサイエンスコーパス: awakening

1 act tonometer (session with nocturnal hourly awakening).

2 was not measured (session without nocturnal awakening).

3 ime to fall asleep, and frequencies of night awakenings).

4 ulses, with a steep rise in amplitude before awakening.

5 id not alter Pdc when measured 4 hours after awakening.

6 Symptom onset commonly occurred on awakening.

7 ultiple pathways to presynaptic dormancy and awakening.

8 r subunit contribution after PDBu-stimulated awakening.

9 depend on circadian phase or sleep stage at awakening.

10 set, shortly after the usual time of morning awakening.

11 distinct despite daily saline eye wash upon awakening.

12 rized by early sleep times and early-morning awakening.

13 as persistent vegetative state or death vs. awakening.

14 voked potential responses have <1% chance of awakening.

15 d sustainable agriculture occurred as a slow awakening.

16 GH every 20 minutes from 9 PM until morning awakening.

17 fore going to bed and immediately on morning awakening.

18 nses were independently associated with late awakening.

19 st cigarette of the day within 30 minutes of awakening.

20 ophy eyes, corneal thickness decreased after awakening.

21 rgeted temperature management may accelerate awakening.

22 total population, both before and following awakening.

23 normothermia has a high predictive value for awakening.

24 over the first days of coma is predictive of awakening.

25 rtPA had to be started </=3 hours of patient awakening.

26 rmance as a function of time since entrained awakening.

27 -reported child sleep duration and nocturnal awakenings.

28 prior hospitalizations, and prior nocturnal awakenings.

29 ep, increased wakefulness, and more frequent awakenings.

30 with greater value when combined with daily awakenings.

31 effect was observed for the number of night awakenings.

32 ing sleep fragmentation (number of overnight awakenings, 1.51 [1.03] at baseline vs 0.92 [0.97] after

33 Saliva samples were obtained at awakening, +15, +30, +45 and +60 minutes on each subsequ

34 nts with clinically evident myoclonus before awakening, 2 expert physicians reviewed and classified a

35 observed for the De Morton Mobility Index at awakening (23%) and minimal ceiling effects across all t

36 2.5%), and the percentage of nights with no awakenings (23.0 +/- 2.5 vs. 15.5+/-2.4%) compared with

37 ling asleep (44.6% vs. 16.6%), early morning awakening (38.9% vs. 12.7%), and hypersomnia (35.0% vs.

38 (> 48 hr from sedation stop; median time to awakening 5 days [range, 3-23 d]) was observed in 78 sub

39 able improvement of the predictive value for awakening (93%, with 95% confidence interval: 0.77-0.99)

40 atosensory evoked potential result, rates of awakening (95% confidence interval) were calculated: adu

41 ry flow (P), reliever use (R), symptoms (S), awakenings (A), and threshold values for change from bas

42 efficiency (SE) and lower number of average awakenings (AA) (P =0.007 0.023 and 0.011, respectively)

43 The night awakenings (Actigraph) pattern was significantly differe

44 igraine triggers such as perfume, stress, or awakening activate multiple hypothalamic, limbic, and co

45 ved from host flora may play a major role in awakening adaptive immunity in neonates.

46 five patients with tonic-clonic seizures on awakening and 30 control subjects had T1-weighted volume

47 ne of four ischemic strokes are noticed upon awakening and are not candidates for intravenous recombi

48 liance by an interprofessional team with the Awakening and Breathing Coordination, Choice of drugs, D

49 Awakening and Breathing Coordination, Delirium monitorin

50 Critically ill patients managed with the Awakening and Breathing Coordination, Delirium monitorin

51 effectiveness and safety of implementing the Awakening and Breathing Coordination, Delirium monitorin

52 entilation status, patients managed with the Awakening and Breathing Coordination, Delirium monitorin

53 models to quantify the relationship between Awakening and Breathing Coordination, Delirium monitorin

54 The awakening and breathing coordination, delirium monitorin

55 was to identify facilitators and barriers to awakening and breathing coordination, delirium monitorin

56 n, we developed, implemented, and refined an awakening and breathing coordination, delirium monitorin

57 e important differences as compared with the awakening and breathing coordination, delirium monitorin

58 In this study of the implementation of the awakening and breathing coordination, delirium monitorin

59 Growing evidence supports the Awakening and Breathing Coordination, Delirium monitorin

60 minimized sedation, paired daily spontaneous awakening and breathing trials, and conservative fluid m

61 pontaneous breathing trials, coordination of awakening and breathing trials, choice of sedation, deli

62 inimizing sedation, paired daily spontaneous awakening and breathing trials, early exercise and mobil

63 orhexidine mouth care, and daily spontaneous awakening and breathing trials.

64 care that combines evidence-based practices: awakening and breathing, coordination with target-based

65 Secondary end points of awakening and discharged alive from hospital trended tow

66 osomal dominant condition with early morning awakening and early sleep times.

67 volatile-based sedation may provide superior awakening and extubation times in comparison with curren

68 short and refreshing naps, few problems with awakening and good response to stimulants, without catap

69 ascular reactivity to hypercapnia on morning awakening and its association with specific sleep-relate

70 and their sequella, including early morning awakening and loss of appetite.

71 vation of CO(2) during apneas contributes to awakening and restoring airway patency.

72 asthma exacerbations and decreased nocturnal awakenings and activities limited by asthma.

73 nsitions among sleep stages, including brief awakenings and arousals, constitute a challenge to the c

74 nsitions among sleep stages, including short awakenings and arousals, constitute a challenge to the c

75 rates and quality of life, reduced nocturnal awakenings and asthma attacks, increased the number of a

76 ght eating symptoms, the number of nocturnal awakenings and ingestions, total daily caloric intake af

77 month follow-up in terms of more nights with awakenings and more days of exercise-related symptoms (b

78 non-REM sleep episodes and in the number of awakenings and movements.

79 mentation was defined as the total number of awakenings and shifts to Stage 1 sleep divided by the to

80 s suggest common dynamical features of brief awakenings and sleep durations across species and may pr

81 levels were measured at wakeup, 30 min after awakening, and at bedtime each day.

82 analyzed independently at coma onset, after awakening, and at follow-up.

83 Symptoms include loud snoring, nocturnal awakening, and daytime sleepiness.

84 (i.e., trouble falling asleep, early morning awakening, and hypersomnia) on the 3-year occurrence of

85 asleep, maintaining sleep, and early morning awakening, and is coupled with daytime consequences such

86 of tender points, FIQ fatigue, tiredness on awakening, and stiffness scores, Clinical Global Impress

87 , 1.04 (95% CI, 0.88-1.22) for early-morning awakenings, and 1.24 (95% CI, 1.05-1.46) for nonrestorat

88 tings, frequency of nocturnal ingestions and awakenings, and caloric intake after the evening meal.

89 the stages of NREM sleep, resulting in fewer awakenings, and increase a physiological measure of slee

90 eneral, perceived sleep quality, sleepiness, awakenings, and sleep efficiency), sleep duration, sleep

91 p-onset latency, total sleep time, number of awakenings, and sleep quality were selected as outcomes.

92 hen deeper levels of sedation and more rapid awakening are required.

93 y increased the percentage of nights with no awakenings as compared with placebo, salmeterol, and FP

94 roblems to maintain sleep, and early morning awakening, as a transdiagnostic symptom for many mental

95 ening, as-needed beta-agonist use, nocturnal awakenings, asthma-specific quality of life, and worseni

96 y expenditure in control mice increased upon awakening at a greater rate than in the narcoleptic mice

97 s were scheduled approximately 4 hours after awakening at baseline and after 1, 5, 10, 14, and 30 day

98 s of breath (OR, 1.6; 95% CI, 1.2 to 2.1) or awakening at night (OR, 1.5; 95% CI, 1.1 to 2.0), and wh

99 s of breath (OR, 2.4; 95% CI, 1.3 to 4.4) or awakening at night in the previous 12 mo (OR, 3.2; 95% C

100 ma with frequent albuterol use and nighttime awakenings at least once weekly.

101 omposer activity and carbon stock: a 'biotic awakening' at depth.

102 omly during the day (random grand mal) or on awakening (awakening grand mal), and juvenile absence ep

103 rneal thickness over the first 4 hours after awakening between 31 mum and 58 mum (95% prediction inte

104 facilitate/hinder the implementation of the awakening, breathing, coordination, delirium, and early

105 five patients with tonic-clonic seizures on awakening, but in none of the 30 control subjects.

106 Activating aNGC neurons triggered awakening by recruiting cholinergic, noradrenergic, and

107 g approaches, we uncovered rapid presynaptic awakening by select synaptic modulators.

108 Awakening by the alpha2-adrenergic antagonist completely

109 , devised by Sloan and colleagues, and night awakenings by use of the Pittsburgh Sleep Quality Index.

110 eased salivary cortisol concentrations after awakening compared with control subjects.

111 e pooled results were evaluated for rates of awakening, confidence intervals, and the possibility of

112 The total number of night awakenings continued to decrease over the remaining foll

113 Beyond 4 hours after awakening, corneas no longer changed considerably in Fuc

114 Conversely, stable post-awakening correlations--such as those found between the

115 3) and CAR measurement indices were derived: awakening cortisol levels, the mean increase in cortisol

116 ents, body mass index (BMI), saliva cortisol awakening curves (area under the curve with respect to t

117 Thus, the torpid/awakening cycle of the hibernating European hamster caus

118 Night awakenings decreased from a mean of 19.5 (SD 14.8) per w

119 Primary outcome measure was awakening, defined as the ability to follow commands bef

120 iii) chronic inflammation is a key factor in awakening dormant malignant cells at the primary site, l

121 wheeze (OR, 5.91; P < 0.01), more nighttime awakening due to cough (OR, 4.20; P = 0.03), increased r

122 , while in a persister cell status, and upon awakening due to exposure to cis-2-decenoic acid (cis-DA

123 onist use for at least 2 days, or night-time awakenings due to asthma for at least one night.

124 that these were spontaneous, as the times to awakening during hypercapnia were much higher than durin

125 Hourly awakening during NCT IOP measurements did not significan

126 Hourly awakening during noncontact tonometer IOP measurements d

127 as difficulty with sleep onset and prolonged awakenings during the night.

128 Epilepsy with grand mal on awakening (EGMA) is a well-defined subtype of idiopathic

129 ur data unveil a CCL5-dependent mechanism of awakening endogenous antitumor immunity triggered by ex

130 sufficient to increase the probability of an awakening event during both slow-wave sleep and rapid ey

131 sufficient to increase the probability of an awakening event in histidine decarboxylase-deficient kno

132 Hcrt neurons increased the probability of an awakening event throughout the entire light/dark period

133 isturbed sleep (US) and two nights of forced awakening (FA) sleep disruption.

134 s also recorded the total time and number of awakening for each patient overnight.

135 ms seem to be unaffected by hourly nocturnal awakening for IOP measurements in young healthy individu

136 Hourly awakening for nocturnal IOP measurements increased wake

137 with GSD to sleep through the night without awakening for therapy while enhancing safety.

138 ation between lateral brain displacement and awakening from acute coma.

139 n back pain with exercise but not with rest; awakening from back pain during the second half of the n

140 However, PPI was smaller at awakening from non-REM sleep compared to established wak

141 Reduced PPI of the startle reflex at awakening from non-REM sleep supports the hypothesis tha

142 hase and are more likely to have their final awakening from NREM sleep than younger adults, our findi

143 PPI after awakening from REM sleep (52.8 +/- 17.9%) was not signif

144 Comparisons between periods of awakening from sedation vs. sedative infusion were made.

145 diabetic subjects exhibited markedly reduced awakening from sleep during hypoglycemia.

146 Awakening from sleep entails rapid re-establishment of c

147 reticular activating system (RAS) can hasten awakening from sleep or light planes of anesthesia.

148 ing from Hcrt neurons is sufficient to drive awakening from sleep states or is simply correlated with

149 ere, we collected serial samples of tears on awakening from sleep, closed eye tears, during a randomi

150 ce, few studies have focused specifically on awakening from sleep.

151 in regional cerebral blood flow (rCBF) upon awakening from stage 2 sleep.

152 frontal and inferior parietal cortices upon awakening from unconsciousness.

153 on, potentially making it possible to create awakenings from complex cases of brain injury.

154 Patient 1, who had a history of night awakenings from pain, reported 101 awakenings owing to p

155 amical patterns and functions of these brief awakenings from sleep are not well understood, and they

156 In this article, we hypothesize that brief awakenings from sleep may reflect aspects of the endogen

157 for 11.5 and 17% of the overall arousals and awakenings from sleep, respectively.

158 the day (random grand mal) or on awakening (awakening grand mal), and juvenile absence epilepsy (JAE

159 enty-eight of 402 patients (57%) awoke: late awakening (> 48 hr from sedation stop; median time to aw

160 n 556 children (1.7%) and frequent nocturnal awakenings (>/=3 times) in 1033 children (3.2%) at 18 mo

161 Postcardiac arrest patients with late awakening had a high rate of favorable outcome, thereby

162 eactivity of the cerebral vessels on morning awakening has been suggested as one of the mechanisms un

163 was no group effect for sleep onset, time of awakening, hours slept, or hours napping.

164 sleep fragmentation (number of arousals and awakenings/hr), but the dedicated noninvasive ventilator

165 Morton Mobility Index) were assessed at ICU awakening, ICU, and hospital discharge.

166 brain displacement are associated with acute awakening in comatose patients.

167 rmed approximately 4.5 hours after scheduled awakening in each cycle so that 12 tests in each subject

168 n diurnal IOP variation and IOP changes upon awakening in habitual and supine positions.

169 Upon awakening in the morning, healthy volunteers collected o

170 t-light exposure be scheduled immediately on awakening in the treatment of most patients with seasona

171 mulation of OH cells (at rates that promoted awakening in vivo) with electrical monitoring of MCH cel

172 tion from theta to alpha rhythm (spontaneous awakening), increased by 13.3% (P<0.01); VT increased by

173 on where both the hibernation period and the awakening intensity are taken into account.

174 Late awakening is frequent after cardiac arrest, despite earl

175 Sleep inertia, or the grogginess felt upon awakening, is associated with significant cognitive perf

176 is distinct, transiently aroused, state upon awakening may serve a protective function, preparing an

177 gh a sequence of CORT pulses--as seen around awakening--may ensure that hippocampal glutamatergic syn

178 d with 2.6% of controls, with blind children awakening much earlier.

179 Awakenings occurred in 19 of 19 trials within 5 min, wit

180 Importantly, this test predicted the awakening of 13 out of 51 patients for which the outcome

181 resulting in a positive predictive value of awakening of 82% (95% confidence interval: 0.65-0.93).

182 Overall our findings indicate that upon awakening of a persister population the cells regain the

183 naling in pfGCs, and these cells trigger the awakening of dormant oocytes and complete the process of

184 We further show that pfGCs trigger the awakening of dormant oocytes through KIT ligand (KITL),

185 rdial follicles and govern the quiescence or awakening of dormant oocytes.

186 growth, energy balance and season, time the awakening of gonadotropin releasing hormone (GnRH) neuro

187 ostate cancer, in particular the apparent re-awakening of key developmental programs that occur durin

188 -nocturnal IOP changes, and IOP changes upon awakening of the converters were significantly different

189 The awakening of the genome after fertilization is a corners

190 ate where to stimulate the brain to force an awakening of the human sleeping brain and vice versa.

191 y lipopolysaccharide treatment, triggers the awakening of these cells, which develop into macroscopic

192 in saliva during the first 30 minutes after awakening on a workday and on a nonworkday.

193 m were used to evaluate the effect of hourly awakening on IOP rhythm.

194 To evaluate the effects of hourly awakening on sleep architecture, comparisons of sleep st

195 (82.4%; 76.5% asymptomatic) were followed by awakenings or arousals.

196 too short duration of sleep or early morning awakening), or a combination of the previous quantitativ

197 were applied either 3-10 s after spontaneous awakenings, or in established wakefulness (> 30 s).

198 ments of the number of hot flushes and night awakenings over time.

199 of night awakenings from pain, reported 101 awakenings owing to pain while taking placebo during the

200 ndividuals for the sessions with and without awakening (P < .05).

201 sleep quality (p = 0.003), feeling rested on awakening (p = 0.007), daytime fatigue (p = 0.02), and f

202 Directly upon awakening, patients had mean corneal thickness of 663 mu

203 m domain, rescue beta-agonist use, nocturnal awakenings, peak expiratory flow diurnal variability, an

204 tion: 44 +/- 6 versus 83 +/- 12 arousals and awakenings per hour (p = 0.02).

205 The number of awakenings per hour of sleep, latency to sleep onset, an

206 e fragmentation index (25 vs 23 arousals and awakenings per hr).

207 e dissipation of sleep inertia effects (post-awakening performance and alertness deficits) is effecte

208 s of regional brain activity across the post-awakening period [in particular, a waning negative corre

209 d every 10 min from healthy males during the awakening period or late afternoon using an automated bl

210 s, operating conditions, various measures of awakening, postoperative nausea and vomiting and dischar

211 epeated IOP measurements requiring nocturnal awakenings, potentially disturbing sleep macrostructure.

212 e, sleep onset problems, poor sleep quality, awakening problems, and daytime disturbances, were all a

213 underpinnings of each of these facets of the awakening process.

214 We employed a provoked awakening protocol where participants were woken up at v

215 After awakening, rabbits were followed up during 7 days.

216 en percent of eyes had symptoms of pain upon awakening refractory to conservative treatment.

217 (aNGC) capable of producing a high degree of awakening represented by a broad high frequency cortical

218 A bigger cortisol awakening response (CAR) was weakly associated with bett

219 tive tasks, disrupted sleep and the cortisol awakening response (CAR), depending on whether it was ex

220 f the cortisol profile, such as the cortisol awakening response and the area under the curve.

221 ted with a time-limited increase in cortisol awakening response and with a sustained improvement in S

222 ntrol were associated with a higher cortisol awakening response the next day, but morning awakening r

223 e Beck Depression Inventory and the cortisol awakening response were measured immediately before and

224 esidual depressive symptoms and the cortisol awakening response) in patients with recurrent depressio

225 s (wakeup level, diurnal slope, and cortisol awakening response) were predicted simultaneously from d

226 risk (Beck Depression Inventory and cortisol awakening response).

227 tionship between job strain and the cortisol awakening response.

228 awakening response the next day, but morning awakening responses did not predict experiences of these

229 cleus (CAUD) activity] suggest that the post-awakening reversal of sleep inertia effects may be media

230 n and 1.57 (95% CI, 1.28-1.93) for nocturnal awakenings; RRs for externalizing problems were 1.77 (95

231 total sleep time (TST) and numbers of sleep awakenings (SA) recorded in the actigraphy, as well as a

232 Herein, a new strategy is outlined for awakening silent gene clusters using small molecule elic

233 ht, trouble getting back to sleep, and early awakenings), sleep duration (short sleep 5 hours or less

234 utcomes included sleep efficiency, number of awakenings, sleep quality, and total sleep time.

235 large brief cardio-respiratory activation at awakening suggest that a distinct, transiently aroused,

236 In recent years, there has been a jarring awakening that liquid-liquid phase separation (LLPS) of

237 sleep onset, sleep efficiency, and number of awakenings that are closer to those obtained by PSG, in

238 infancy and may be an instrumental factor in awakening the potential of group 14 chemistry for applic

239 and measured TMS-evoked EEG responses before awakening the subjects and asking them if they had been

240 After PDBu-induced awakening, these previously dormant terminals had a syna

241 osture-independent IOP pattern around normal awakening time is different in eyes with early glaucomat

242 Median awakening time was 4 minutes (2.2-5 min).

243 Around normal awakening time, the supine IOP increased in the glaucoma

244 bjects reported no conscious experience upon awakening, TMS evoked a larger negative deflection and a

245 We found time since entrained awakening to be the major predictor of peak performance

246 mitted helminths, the worldwide community is awakening to the importance of these infections.

247 Upon awakening, transgenic and control mice displayed a simil

248 ed wide variation in approach to spontaneous awakening trial performance and patient selection.

249 ality improvement collaborative, spontaneous awakening trial practice varies widely and concerns pers

250 t institutional characteristics, spontaneous awakening trial practice, attitudes and barriers regardi

251 tics and attitudes with reported spontaneous awakening trial use was evaluated using logistic regress

252 of respondents reported regular spontaneous awakening trial use, defined as greater than 75% of mech

253 sitively associated with regular spontaneous awakening trial use, whereas the perception that spontan

254 gatively associated with regular spontaneous awakening trial use.

255 ficantly associated with regular spontaneous awakening trial use.

256 Implementation of daily paired spontaneous awakening trials (daily sedation vacation plus spontaneo

257 reathe protocol that pairs daily spontaneous awakening trials (ie, interruption of sedatives) with da

258 thesized that daily, coordinated spontaneous awakening trials (SATs) and spontaneous breathing trials

259 Spontaneous awakening trials (SATs) improve outcomes in mechanically

260 of 1309) has a written policy on spontaneous awakening trials (SATs), but the minority of respondents

261 to assess a protocol that paired spontaneous awakening trials (SATs)-ie, daily interruption of sedati

262 the effect of concerns regarding spontaneous awakening trials and are associated with increased perfo

263 n, and Manage Pain; "B" for Both Spontaneous Awakening Trials and Spontaneous Breathing Trials; "C" f

264 -6.43]), and the perception that spontaneous awakening trials are hard work (odds ratio, 0.53 [95% CI

265 trials, and the perception that spontaneous awakening trials are hard work were negatively associate

266 ons were less likely to perceive spontaneous awakening trials as hard work (odds ratio, 0.44 [95% CI,

267 s routinely in rounds and having spontaneous awakening trials as part of unit culture were positively

268 y ventilated patients undergoing spontaneous awakening trials each day.

269 d with routine implementation of spontaneous awakening trials in an ICU quality improvement collabora

270 use, whereas the perception that spontaneous awakening trials increased short-term adverse effects, s

271 I, 1.55-5.23]), incorporation of spontaneous awakening trials into unit culture (odds ratio, 3.36 [95

272 ents (44%, 446 of 1019) practice spontaneous awakening trials on more than half of ICU days.

273 attitudes and barriers regarding spontaneous awakening trials, and organizational cultural characteri

274 of attitudes and fears regarding spontaneous awakening trials, and organizational practices associate

275 adverse effects, staff fears of spontaneous awakening trials, and the perception that spontaneous aw

276 irium management strategies with spontaneous awakening trials, spontaneous breathing trials, and earl

277 tion, and delirium management to spontaneous awakening trials, spontaneous breathing trials, and ICU

278 The ABCDE bundle consists of spontaneous awakening trials, spontaneous breathing trials, coordina

279 y and concerns persist regarding spontaneous awakening trials.

280 operative) or deep sedation (patient asleep, awakening upon physical stimulation).

281 r event, and hypertension treatment time (on awakening versus at bedtime; per 1-SD elevation: hazard

282 jective measures of sleep latency, number of awakenings, wake time after sleep onset, total sleep tim

283 sidering single neurophysiologic tests, late awakening was associated with a higher proportion of dis

284 Time to awakening was calculated starting from initial sedation

285 Late awakening was more frequent with midazolam (58% vs 45%)

286 Awakening was usually before sunrise.

287 irst night, the baseline rate of spontaneous awakenings was determined by polysomnography.

288 tion, measured as the number of arousals and awakenings, was greater during pressure support than dur

289 ircadian phase and an interval elapsed since awakening were attributed to each data point, and circad

290 ivariate analysis, independent predictors of awakening were younger age (odds ratio [OR] = 1.039, 95%

291 In both experiments, forced awakenings were applied to achieve rapid recovery from a

292 2 Hz) throughout the cortex, and spontaneous awakenings were preceded by an increase in BG beta activ

293 needed medication, and number of nights with awakenings were similar between genotype groups.

294 remission) with severe hot flushes and night awakenings were treated with stellate-ganglion block at

295 espiratory symptoms (dyspnoea and night-time awakenings) were grouped into one cluster, while the oth

296 f the PPT region during sleep leads to rapid awakening, whereas lesions of the PPT in cats reduce REM

297 placebo during the maintenance period and 32 awakenings while taking carbamazepine.

298 10.3 +/- 2.6 LSN and 2.6 +/- 0.6 hours from awakening with deficits.

299 naps, prolonged night-time sleep, difficult awakening with sleep drunkenness and prominent mood dist

300 ssue by comparing the EEG activity preceding awakenings with recalled vs. no recall of dreams using t