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1 mmaplysilla purea, which is known to inhibit axonemal dynein.
2 a specific centrin function associated with axonemal dynein.
3 identified as subunits of cytoplasmic and/or axonemal dyneins.
4 d to be light chains of both cytoplasmic and axonemal dyneins.
5 LCs) have been found in both cytoplasmic and axonemal dyneins.
6 e analogous to the B-link described for some axonemal dyneins.
7 do different things, as is the case for the axonemal dyneins.
8 but not the other components, corresponds to axonemal dyneins.
9 play an essential role in the regulation of axonemal dynein activity and thus of ciliary and flagell
10 The addition of kinase inhibitor restored axonemal dynein activity concomitant with the dephosphor
12 amily proteins were originally identified in axonemal dyneins and subsequently found to function in m
20 mport into cilia and flagella, multi-subunit axonemal dynein arms are thought to be stabilized and pr
21 unchanged or become elevated, the density of axonemal dynein arms is reduced in reptin(hi2394) mutant
22 cluding the intraflagellar transport system, axonemal dynein arms, radial spokes, the 96-nm ruler, an
25 ized oda mutants, but only a partial loss of axonemal dyneins as shown by both electron microscopy an
26 Assembly Factors; DNAAFs) are necessary for axonemal dynein assembly, although the detailed mechanis
32 bules with MTBDs of cytoplasmic dynein-1 and axonemal dynein DNAH7 and determined their cryo-EM struc
33 oward visualizing the ATPase activity of the axonemal dyneins during bending, we have investigated th
36 Dense populations of microtubules driven by axonemal dynein form large vortices, providing insights
38 arious cellular transport systems, including axonemal dyneins generating the force for ciliary and fl
41 allele of the testis-specifically expressed axonemal dynein heavy chain (axDHC) gene, Dnahc8, has be
42 acterized an insertional mutation in a mouse axonemal dynein heavy chain gene (Mdnah5) that reproduce
44 culture demonstrated that the expression of axonemal dynein heavy chains correlated with the develop
45 fication and partial cloning of seven unique axonemal dynein heavy chains from rat tracheal epithelia
47 r specifically required for the stability of axonemal dynein heavy chains in cytoplasm and suggest th
48 gulate the cell-specific expression of these axonemal dynein heavy chains will further our understand
49 level of conservation does not extend to the axonemal dynein heavy chains, suggesting functional diff
50 Here we report the positional cloning of an axonemal dynein heavy-chain gene, left/right-dynein (lrd
51 ity, can influence the activity of outer arm axonemal dynein in motility assays using purified protei
53 Pontin is essential for the stabilization of axonemal dynein intermediate chain 1 (DNAI1) and DNAI2,
54 This allows for the incorporation of these axonemal dyneins into the axoneme directly from the cyto
62 a novel RNP granule containing the mRNAs for axonemal dynein motor proteins becomes highly polarized
65 noregulatory complexes with their associated axonemal dynein motors provide a mechanism for the long-
67 tory beating patterns, the activities of the axonemal dyneins must be coordinated both spatially and
69 cle cryo-EM reconstruction of a three-headed axonemal dynein natively bound to doublet microtubules i
70 ubunits, and cytoplasmic factors involved in axonemal dynein preassembly (DNAAFs) are associated with
79 tains an 18-residue insertion, found in many axonemal dyneins, that contacts the adjacent protofilame
81 sity directly influences the activity of the axonemal dyneins, the motors that drive the beating of t
83 to a higher rate of binding of Chlamydomonas axonemal dynein to Chlamydomonas microtubules than to po
84 x specifically localizes the linear array of axonemal dyneins to the doublet microtubule by directly
85 ersity can directly regulate the activity of axonemal dyneins, we asked whether in vitro acetylation