ライフサイエンスコーパス: backcross

1 ons were identified using a three-generation backcross.

2 )) mice were generated and used at the ninth backcross.

3 information of any genotyping strategy in a backcross.

4 d skin cancer in NIH/Ola by SPRET/Outbred F1 backcrosses.

5 ge effect sizes were found in two reciprocal backcrosses.

6 four different M. spretus by M. musculus F1 backcrosses.

7 of markers to reveal previously undetectable backcrosses.

8 lyzed recombinant inbred strains and linkage backcrosses.

9 e parental gene pools in advanced generation backcrosses.

10 n efficient method for genotyping progeny of backcrosses.

11 er genetic loci without the need for lengthy backcrossing.

12 om past interbreeding with dogs, followed by backcrossing.

13 populations of gray wolves probably through backcrossing.

14 flow and introgression from one another via backcrossing.

15 a high throughput fashion in the absence of backcrossing.

16 D) and spontaneous diabetes in NOD.RAG(-/-) (backcross 1 generation).

17 ion in perforin-deficient mice, we generated backcross 1 progeny by crossing (129 x B6)F(1) PKO mice

18 In transplantation experiments, >350 backcross 1 progeny were analyzed and displayed a great

19 1 TCR is sufficient to cause diabetes at NOD backcross 1, bypassing polygenic inhibition of insulitis

20 ed C57BL/6x129sv genetic background and then backcrossed 12 times onto the C57BL/6 background.

21 We developed this population by backcrossing 25 wild barley accessions to the six-rowed

22 more rapid LD decay than comparable advanced backcross (28.6 cM) and recombinant inbred line (32.3 cM

23 reference genome sequence, was derived from backcrossing a Phytophthora root rot resistance locus fr

24 By backcrossing a Slc11a1 knockout allele onto the NOD gene

25 ecG1 line and of their segregation following backcross allowed us to build a model to explain how a n

26 These backcrosses also indicated that deleterious mutations ha

27 s underlying these clinical observations, we backcrossed an established psoriasiform mouse model (IL-

28 e inherited mA3 allele in a C57BL/6 x BALB/c backcross analysis.

29 Here, we present a quantitative genetic "backcross" analysis of sympatric Neochlamisus bebbianae

30 of allele-specific imbalances in tumors from backcross and congenic mice to refine the location of Sk

31 Second, later generation (backcross and F(2)) hybrid male sterility between D. vir

32 forming a genetic modifier screen through F1 backcross and F1 intercross matings.

33 For this report, recombinant backcross and F2 progeny derived from C57BL/6J and AKR/J

34 olymorphic chromosomal regions following the backcross and single-seed descent generations of the bre

35 seful assays for genotyping on interspecific backcross and whole-genome radiation hybrid cell panels.

36 ree genomic QTL scans (two reciprocal worker backcrosses and one drone hybrid population) derived fro

37 A1cf and Ago2 mutant intercrosses but not in backcrosses and without fetal loss.

38 Backcrossing and complementation confirmed the importanc

39 than conventional trait introgression using backcrossing and marker-assisted selection.

40 t introgression strains produced by repeated backcrossing and phenotypic selection, we show that thes

41 ls Lymnaea stagnalis were self-fertilised or backcrossed, and the genotype of more than six thousand

42 osome blocks was produced by daughter-father backcrosses, and inferred from marker loci positioned vi

43 nd ancestry proportions of their hybrids and backcrosses, and track the origin (wild or domestic) of

44 indica (rice 9311), through multi-generation backcrossing, and generated a nearly isogenic, blight-re

45 A genome-wide linkage analysis of backcrossed animals with EAG revealed a major quantitati

46 as 2 loci unlinked to Vwf (Mvwf6-7) using a backcross approach with the inbred mouse strains WSB/EiJ

47 lthough significant lethality occurs in this backcross ( approximately 50%), differences in the level

48 oportions are expected to be similar for all backcrosses ( approximately (3/4) from one parental type

49 We show that hybridization and subsequent backcrosses are directionally biased and that the only l

50 e of two hybrid classes, F1s and var. incana backcrosses, as would be expected on a relatively young

51 Here, we have generated a backcross (BC) population (n = 166) where Crgn1 and Crgn

52 A reciprocal backcross (BC) population (total 2052 individuals) was g

53 A real data set of a backcross (BC) population from an interspecific hybrid b

54 A large backcross (BC)1 population derived from a cross between

55 ed into 91 (NODxB6.H2(g7))F1xB6.H2(g7) first-backcross (BC1) females.

56 We planted reciprocal backcross (BC1) hybrids along with pure-species plants i

57 e examined line crosses of reciprocal F1 and backcross (BC1) hybrids and determined that flowering ti

58 Bcl-3-deficient NOD mice were generated by backcrossing Bcl-3-deficient C57BL/6 mice to NOD mice.

59 tch" in the relative fitnesses of reciprocal backcrosses between environments.

60 Backcrosses between esk1-5 and two independent knockout

61 s based on the breeding scheme of reciprocal backcrosses between reciprocal F(1) hybrids and original

62 itance of thelytoky, we generated reciprocal backcrosses between thelytokous A. m.capensis and the ar

63 Our results show recurrent backcrossing between sexual and parthenogenic Darevskia

64 By backcrossing Brown-Norway HK-deficient rats with Lewis r

65 es a short isoform of CTLA-4 (1/4 CTLA-4) by backcrossing C57BL/6.1/4CTLA-4-transgenic mice to the MR

66 erved in adenomas from parous mice (line and backcrossed) carrying the line I Min allele relative to

67 are determined explicitly through only four (backcross case) or nine (intercross case) independent st

68 analyze the role of CCR7 in autoimmunity, we backcrossed CCR7(ko/ko) mice (in which ko signifies defi

69 junction with a large Arabidopsis reciprocal backcross data set to gain "mechanistic" insights into t

70 rom an Elymus trachycaulus/Triticum aestivum backcross derivative.

71 Then, using a reciprocal backcross design, we performed high-resolution genetic m

72 njury survival time using a mouse reciprocal backcross design.

73 sis in wide hybridizations of plants using a backcross design.

74 Backcrossing Dysf(-/-) mice with mice lacking signaling

75 ference in memory retention was studied in a backcrossing experiment in which the phenotype of N. gir

76 of a small number of mutations indicated by backcross experiments yielded designs with substitutions

77 Through a series of backcrossing experiments with an uninfected Trichogramma

78 Both mutations segregated in backcrossed F(2) populations as homozygous recessive all

79 Backcrossing F1 hybrid females between these two species

80 ity is inherited through F1 (SD x LE) and N2 backcross (F1 x SD) generations via an orderly pattern (

81 s with each of them derived from one of four backcross families.

82 allozyme markers, and phenotypic sex in four backcross families.

83 locus (D11Mit39) was confirmed in RA-treated backcross fetuses of F(1) females to C57BL/6N males.

84 t specifically lack GIP-producing cells were backcrossed five to eight times onto the diabetogenic NO

85 EDF+, T+, S+, probably resulted from random backcrossing followed by stabilization through selection

86 The resistant progeny were identified during backcrossing for five generations.

87 pecific widerwing (wdw) locus, which we have backcrossed from N. giraulti into N. vitripennis and map

88 A follow-up study using consecutive backcrosses from Dahl salt-sensitive rats and Lewis iden

89 in hybrids decays with increasing number of backcross generations as expected from theory and approa

90 population size, replication, and number of backcross generations to their needs.

91 HMS in hybrid males from early but not later backcross generations.

92 ed to the sickly plant phenotype in advanced backcross generations.

93 ed on both the D. simulans and D. mauritiana backcross genomic background, suggesting a cis-acting re

94 and met(Att)/met(lab) and met(lab)/met(lab) backcross genotypes are strongly associated with metamor

95 within and among the mix of parental, F1 and backcross genotypes that are currently present.

96 The backcross has yielded two strong candidate intervals wit

97 ugh spontaneous hybridization and subsequent backcrossing has been documented; however, the evolution

98 hat these three reproductive morphologies of backcross hybrid males produce divergent gene expression

99 tion (UVR)-induced melanoma in a Xiphophorus backcross hybrid model previously reported to be suscept

100 dest amounts of the phenotypic variance of a backcross hybrid population.

101 asure recombination rate, we genotyped 1,294 backcross hybrids at 50 markers across the largest assem

102 Backcross hybrids toward I. fulva (BCIF) also survived a

103 ibited strong epistatic interactions in male backcross hybrids, but only one pair of QTL interacted i

104 Through the use of reciprocal F1 and backcross hybrids, we show that morphological traits imp

105 In backcross hybrids, we show that precocious burrowing and

106 the parental taxa, and was fully restored in backcross hybrids.

107 ffect on hybrid sterility in both reciprocal backcross hybrids.

108 ea and D. yakuba and in the female D. yakuba backcross hybrids.

109 To cover a wide range of HLA phenotypes, we backcrossed IFN-alpha/betaR(-/-) mice with HLA A*0201, A

110 lysis of lines from an independently derived backcross inbred line population.

111 ine cmQTL using an independent population of backcross inbred lines, derived from the same parents, w

112 of chromosome segment substitution lines and backcrossed inbred lines suggested that NOMT is the unde

113 rescue frequency among subgroups within the backcross indicate gender and parent of origin influence

114 thin 105 kb of its true position using 96 F1-backcross individuals genotyped in a single lane on an I

115 ate with parental species, resulting in many backcrossed individuals with a small proportion of intro

116 variety of segregating populations including backcrosses, intercrosses, and natural populations.

117 isting of any arbitrary sequence of selfing, backcrossing, intercrossing and haploid-doubling steps t

118 itially affect mouse size or viability, upon backcross into C57BL/6J mice some Rap1a-/- embryos died

119 When introgressed by backcross into the maize inbred line PH09B, the mutant p

120 When these three insertions are backcrossed into an otherwise wild-type genetic backgrou

121 Mice that lacked PI3Kgamma were backcrossed into db/+ mice C57BL/KS (>10 generations) to

122 ed in the C57BL/6 inbred strain and has been backcrossed into the BALB/cBy strain for over 11 generat

123 a-eGFP (D1-GFP), and Drd2-eGFP (D2-GFP) mice backcrossed into the C57BL/6 background.

124 is study, Apoe-/- mice lacking SR-A or CD36, backcrossed into the C57BL/6 strain for 7 generations, w

125 l conductance (Gj) using carbenoxolone or by backcrossing into a cardiomyocyte-specific Cx43 (connexi

126 Apc(Min/+)) congenic strain was generated by backcrossing into BALB/c the Apc(Min) allele from C57BL/

127 Interestingly, after backcrossing into the C57BL/6 background, RD-fed Grp78(+

128 PsGA3ox1 (LE) was introduced, by a series of backcrosses, into the same genetic background (BC LEle).

129 g a recombinant inbred line population and a backcross introgression line population.

130 This modifier was also identified in a backcross involving 129X1/SvJ and B6 Apc(Min/+) mice.

131 1.B6-Cdh23(ahl) congenic mice, and a linkage backcross involving these strains localized a Chr 10 QTL

132 ABR threshold variation among mice from two backcrosses involving BUB/BnJ mice with mice of strains

133 viral functions of IRF5 in vivo, we infected backcrossed Irf5-/-xDock2wt/wt mice (here called Irf5-/-

134 2 intercross-like segregation) or 1:1 ratio (backcross-like segregation).

135 One advanced backcross line carrying the major-effect QTL on chromoso

136 We used a serially backcrossed line of the diamondback moth, Plutella xylos

137 Roots of tt4(2YY6), the backcrossed line tt4-2, and two other tt4 alleles had wi

138 sts with parental, reciprocal F1 and F2, and backcross lines.

139 We constructed a collection of 881 backcrossed lines containing mutant alleles that induce

140 ept we used phenotype-based introgression to backcross loci that control innate food preference in Dr

141 CG5762 is underexpressed in sterile backcross males compared with their fertile brothers.

142 etween backcross males with motile sperm and backcross males with immotile sperm.

143 ificant differential gene expression between backcross males with motile sperm and backcross males wi

144 ross males with no sperm compared with those backcross males with motile sperm and immotile sperm, bu

145 gnificantly differentially expressed between backcross males with no sperm compared with those backcr

146 ity differ between D. yakuba and D. santomea backcross males, both in terms of the magnitude of main

147 duced fertility of D. yakuba and D. santomea backcross males.

148 We produced 246 backcross mapping (BC(1)) progeny by crossing a naturall

149 tomas by a factor of 2.5 in first-generation backcross mice (C.iMyc(Emu) N1).

150 s taken using (B10.BR x BALB.K)F(1) x B10.BR backcross mice as recipients.

151 the total ABR threshold variation among the backcross mice at all ages.

152 H/Ola x (M. spretus x M. musculus NIH/Ola)F1 backcross mice depends on interactions with another unli

153 athy, we performed a genome-wide scan in 165 backcross mice generated between the nephropathy-sensiti

154 Genome scans of N2 backcross mice identified a significant modifier locus o

155 A previous analysis of SNF(1) x NZB backcross mice revealed the existence of 4 SWR loci (H2

156 roliferation are differentially regulated in backcross mice susceptible or resistant to tumour develo

157 In burrows built by first-generation backcross mice, entrance-tunnel length and the presence

158 ygous regions of the genome in interspecific backcross mice, providing an efficient method for genoty

159 Using N2 backcross mice, we mapped the trait with high resolution

160 rs8259436 and D15Spn14, using data from 1396 backcross mice.

161 271 (129S6/SvEvTac x BALB/cJ)F(1) x BALB/cJ backcross mice.

162 one-half of the phenotypic variation in the backcross mice.

163 0% of the hearing threshold variation in the backcross mice.

164 nt study extends our previous findings using backcrossed mice and covering various experimental condi

165 Finally, eighth generation backcrossed mice harboring prl1 were found to maintain r

166 via bioluminescence imaging and extensively backcrossed mice onto the albino C57BL/6 genetic backgro

167 c scan of chromosome 1 with 35 infected F(1) backcrossed mice revealed that resistance to KIM5 maps t

168 A second screen of 95 backcrossed mice verified that this locus confers resist

169 genes and enhancer elements in congenic and backcross mouse models.

170 We then generated a segregating backcross (n = 200) between the BALB.K and B10.BR strain

171 were produced by NOD x (NOD x 129.H2(g7))F1 backcross (N2).

172 trated the utility of a wild barley advanced backcross-nested association mapping (AB-NAM) population

173 Analysis of 214 mice from a backcross of (B6.CAST-Cdh23 Ahl+ xDBA/2J) F1 hybrids to

174 Analysis of 225 N2 mice from a backcross of (C57BL/6JxDBA/2J) F1 hybrids to DBA/2J mice

175 Analysis of tumor development in a backcross of (FVBB6 Apc(Min/+)) x B6 Apc(Min/+) mice has

176 eda x Pinus elliottii) x P. elliottii pseudo-backcross of 345 full-sibs (BC1).

177 Female mice from a backcross of C3H/HeJ and (BALB/cxC3H/HeJ)F1 mice were in

178 detecting new epistatic QTL for obesity in a backcross of CAST/Ei mice onto M16i.

179 actor (SRF) homozygous-null embryos from our backcross of SRF(LacZ/)(+) "knock-in" mice failed to gas

180 ed early flowering segregants derived from a backcross of the Bowman(eam5) introgression line.

181 er data were collected from the progeny of a backcross of two species of Saccharomyces cerevisiae.

182 l2/Cx3cr1 double knockout mice obtained from backcrosses of CCDKO with C57Bl/6 mice.

183 associated with lymphoma was conducted in F1 backcrosses of NZB and a control strain, DBA/2.

184 Reciprocal backcrosses of pgd2-1 suggested that missing PGD activit

185 lity and genome instability triggered by the backcrossing of Bravo teosinte with maize.

186 ion of congenic sublines of mice by repeated backcrossing of CAST with B6 mice and phenotype characte

187 Here we find that continued backcrossing of Taf7l(-/Y) mice from N5 to N9 produced K

188 Here, we demonstrate that the backcrossing of wild mice with knockout mutant laborator

189 genotypes in approximately 8,000 individual backcrossed offspring (17 mapping populations with rough

190 ice, this interesting study relied upon mice backcrossed on the outbred Swiss Webster (SW) strain tha

191 eration but are transmitted in outcrosses or backcrosses only by the C24 genomic segment.

192 ted novel BALB/c.Mdr2(-/-) mouse via genetic backcross onto highly fibrosis-susceptible BALB/c substr

193 -Cre.Irf4 (fl/fl) and Irf4 (fl/fl) mice were backcrossed onto a Rag-1 (-/-) background and used as re

194 ddition, Cyp17a1 heterozygous mice were also backcrossed onto an Apoe KO atherogenic background and f

195 The COX-2 deficiency was also backcrossed onto both DBA and C3H backgrounds to confirm

196 , 3H9 and 56R, with specificity for DNA were backcrossed onto the C57BL/6 background with or without

197 how or a high-fat diet (HFD) for 4 weeks, or backcrossed onto the db/db background.

198 background by outcrossing to C57BL/10J, and backcrossing or intercrossing.

199 ation, we characterized a second, 374-member backcross panel for the inheritance of five microsatelli

200 Using a forward genetic approach in a backcross panel of mice, we identified cylindromatosis (

201 some, we produced a 103-member intraspecific backcross panel that segregated for jal, and typed it fo

202 ttern in the F1, which is then maintained in backcross plants independent of the presence of the pare

203 To this end, a backcross population (BC1F2) segregating for the glossy

204 variation for days to heading in an advanced backcross population derived from the Oryza sativa varie

205 en-treated cohort compared with an untreated backcross population.

206 in the onset of cardiomyopathy in a CAST/EiJ backcross population.

207 performed on A. halleri x Arabidopsis lyrata backcross population1 identified the metal-pump gene Hea

208 Backcross population1 individuals displaying the A. hall

209 perimental crosses of inbred line species in backcross populations.

210 s, that have increased in copy number in the backcross populations.

211 Ten generations of backcrosses produced N10F1 rats, which were intercrossed

212 chromatin were quickly identified from 1048 backcross progenies through disease screening and molecu

213 We analyzed 1134 backcross progeny from a cross between the obligate FW s

214 ed genotyping in such species using a pseudo-backcross progeny of 154 individuals of Populus trichoca

215 A genetic screen of 176 N2 backcross progeny of two Trp53(+/-) strains, BALB/c and

216 e on chromosome 2 in [(C/B)F1xC]N2-Tmc1Bth/+ backcross progeny, and three other QTL on chromosomes 11

217 rtship wing display are highly correlated in backcross progeny, suggesting that linkage or pleiotropy

218 Using phenotypic and genetic analysis of backcross progeny, we further demonstrate that both the

219 of the phenotype confirmed by generation of backcross progeny.

220 generated for 2608 genes in 91 interspecific backcross progeny.

221 A T1 population of 11,000 selfed and cv M82 backcrossed progeny was produced from the functional T0

222 We have generated a fully backcrossed properdin-deficient mouse line by convention

223 nesis, we created a transgenic murine model, backcrossing RAGE-null mice to a spontaneous mouse model

224 Backcrossing rd1 with C57BL6 mice reveals the complete l

225 mosome 2B and goatgrass 2S chromatin using a backcross scheme favorable for inducing and detecting th

226 osomal determinants of susceptibility with a backcross scheme that exploited a paternal, parent-of-or

227 we analysed ABR thresholds of progeny from a backcross segregating MRL and B6 alleles.

228 Marker-assisted selection was used to backcross selected introgressions into tomato, to recove

229 tions, but not a limited introgression after backcrossing several generations of female hybrids to ma

230 ad to increased detection of late-generation backcrosses, shed light on the consequences of anthropog

231 Specifically, each backcross should exhibit higher fitness in the environme

232 ng lineages will be F1s and first-generation backcrosses sired mainly by the outcrossing lineage, tog

233 -linked loci polymorphic between 129 and the backcrossing strain resulted in systematic genetic confo

234 uantitative trait locus analysis using an N2 backcross strategy revealed a single major quantitative

235 on C9 was substantiated by scoring recurrent backcross substitution lines, derived from the same pare

236 We backcrossed the Cd59a knockout (Cd59a(-/-)) mouse onto t

237 We backcrossed the Ins2(Akita) mutation onto the NOD-Rag1(n

238 Gba1 mutants, mouse models were generated by backcrossing the above homozygous mutant GCase mice into

239 physiologically highly useful mouse model by backcrossing the original line with C57/BL6J mice.

240 o outcross mutant mice to another strain and backcross them, and (3) exclusion of genes not involved

241 e the utility of R/cape by analyzing a mouse backcross, thereby discovering novel epistatic interacti

242 dy, we eliminate clinical biliary disease by backcrossing this Pkhd1 mutation onto the C57BL/6 geneti

243 lesions, which appeared at various stages of backcross to C57BL/6, bore resemblance to the rd8 retina

244 e pair of QTL interacted in females from the backcross to D. yabuka.

245 normal skin from a M. musculus x M. spretus backcross to generate a network view of the gene express

246 genome-wide association study in N2(129xABH) backcross to map polymorphic cannabinoid drug pump; and

247 e 1 diabetes resistance or susceptibility in backcross to NOD/LtJ.

248 mapping was performed in an (AKR x SAMP1/Fc) backcross to SAMP1/Fc, followed by sequencing, expressio

249 subset of DJ-1-nullizygous mice, when fully backcrossed to a C57BL/6 [corrected] background, display

250 Mesangial cells from itgb8-/- mice backcrossed to a genetic background that permitted survi

251 Using a design in which each RI line was backcrossed to both parental lines, we mapped seven QTL

252 GHS x WKY rats were backcrossed to breed for congenic rats with the chromoso

253 Dnd1(Ter/Ter); Bax(-/-) double mutants were backcrossed to C57BL/6J, no tumors arose.

254 e severity of DN in eNOS(-/-) mice that were backcrossed to C57BLKS/J db/db mice.

255 LR4, their littermates, and villin-TLR4 mice backcrossed to DUOXA-knockout mice.

256 of colitis, p110delta(D910A/D910A) mice were backcrossed to IL-10(-/-) mice.

257 ne transmission, were identified and further backcrossed to MA/My.L-H2(b) or C57L mice.

258 1 in diabetes, Il21r-knockout (KO) mice were backcrossed to NOD mice.

259 ce, and transgenic offspring were repeatedly backcrossed to NOD.H2(h4) mice.

260 GCase, saposin C deficient mice (C-/-) were backcrossed to point mutated GCase (V394L/V394L) mice.

261 The Siglec-G-deficient mouse was also backcrossed to the autoimmune prone MLR/lpr background.

262 when the original mMCP-6 knockout mice were backcrossed to the BALB/c strain, these mice were carryi

263 When backcrossed to the Kit(W-Sh) background, mev mice had ma

264 Furthermore, FRG mice backcrossed to the NOD background and repopulated with h

265 ids were created for each Am strain and then backcrossed to their respective Am line.

266 3) transgenic mice overexpressing tmTNFalpha backcrossed to TNFalpha-KO mice (tmTNFalpha-transgenic/T

267 In backcrosses to an unmethylated Ler allele, the newly met

268 our QTL were detected in male hybrids in the backcrosses to both D. santomea and D. yakuba and in the

269 d using classical genetic methods, including backcrosses to demonstrate reversion or suppression in r

270 ecies together with F1s and first-generation backcrosses to G. rivale alone.

271 terval mapping approach with two Africanized backcrosses to identify quantitative trait loci (QTL) un

272 type strains was generated by a series of 11 backcrosses to introgress the MAT locus from a nonoutbre

273 -LEW background as well as after at least 10 backcrosses to LEW rats.

274 med from a multi-strain cross with two final backcrosses to LG before being inbred by brother-sister

275 encing method (REGRES) and performed genetic backcrosses to purge mutations not required for Cit(+) f

276 Finally, the use of backcrosses to render the hybrid genome partial homozygo

277 generation (F2) of the F1 X F1 intercross or backcrosses to the parental strains.

278 und, eliminating the need for generations of backcrossing to achieve congenic animals.

279 BL/6 Optn(470T/470T) mice, but after further backcrossing to C57BL/6, offspring viability was restore

280 However, upon backcrossing to maize, the BC(1) and subsequent generati

281 After repeated backcrossing to the C57BL/6J background, we compared the

282 carcinomas drops gradually in the course of backcrossing to the FVB/N background.

283 lants are never again recovered by continued backcrossing to the normal maize parent.

284 lting hybrids formed the new species without backcrossing to the parents.

285 /Ola x (Mus spretus x M. musculus NIH/Ola)F1 backcrosses, to identify a skin tumor susceptibility loc

286 gnificantly higher rates than the reciprocal backcross toward I. brevicaulis (BCIB).

287 , notably the switch in relative fitness for backcross types, the expected rank order of cross type f

288 le-specific viability, female fertility, and backcross viability.

289 A large-scale backcross was performed to generate a population of colo

290 ny of a B6CBAF1 intercross and a CBAxB6CBAF1 backcross were performed.

291 ed mice with that of two Crb1(rd8/rd8) lines backcrossed with C57BL/6JOlaHsd mice.

292 In this study, SRC-1(-/-) mice were backcrossed with FVB mice and then cross-bred with MMTV-

293 ctably develop prostate adenocarcinoma, were backcrossed with gammadelta T cell-deficient mice (TCRde

294 mCherry fluorescence on ophthalmoscopy were backcrossed with normal males for eight generations.

295 Through 10 generations of backcrossing with Columbia-0 (Col-0), we partially rescu

296 High free LC levels were achieved after backcrossing with mice presenting increased PC different

297 tic mapping strategy that involves recurrent backcrossing with phenotypic selection to obtain new ins

298 story of this unisexual species has included backcrossing with the parent species before the onset of

299 tion of sexual reproductive machinery allows backcrossing with their sexual ancestors.

300 Further backcrossing yielded mMCP-6(-/-) mice with the BALB/c MH