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1 amples did not contain significant levels of bacterial DNA.
2 LR9) activation is attributed to delivery of bacterial DNA.
3 involves activation of TLR9-ERK signaling by bacterial DNA.
4 y unrecognized potential for the exchange of bacterial DNA.
5 CpG motifs are present at high frequency in bacterial DNA.
6 ge regions, accounting for 2.7% of the total bacterial DNA.
7 (PFGE) of NotI restriction enzyme digests of bacterial DNA.
8 to contamination of laboratory reagents with bacterial DNA.
9 r label-free and ultrasensitive detection of bacterial DNA.
10 through cGAS-STING-dependent recognition of bacterial DNA.
11 8 log10 gene copies (GC)/g, respectively, in bacterial DNA; 5.5 and 4.4 log10 GC/g, respectively, in
14 etermine whether exposure of immune cells to bacterial DNA affects DNA binding and internalization.
15 ing is able to induce some compaction of the bacterial DNA, although to a lesser extent than demixing
16 is required for transient expression of the bacterial DNA, an early step in the transformation proce
17 nicircle' DNA, a vector type that is free of bacterial DNA and capable of high expression in cells, f
18 binding to two distant operator sites on the bacterial DNA and causing the intervening DNA to form a
20 easingly clear that eukaryotes have acquired bacterial DNA and function through horizontal gene trans
21 o demonstrate that the third detector senses bacterial DNA and identify it as Aim2, a receptor that h
25 ethylated DNA sequences that mimic viral and bacterial DNA and protect against infectious agents and
26 to spacer acquisition from both foreign and bacterial DNA and results in multiple spacers incapable
27 )17 cell-derived IL-26 formed complexes with bacterial DNA and self-DNA released by dying bacteria an
28 a significant correlation between levels of bacterial DNA and serum tumor necrosis factor-alpha (P =
29 cytosolic surveillance pathway, which senses bacterial DNA and signals through STING, TBK1, IRF3 and
31 these, TLR9, is activated intracellularly by bacterial DNA and synthetic oligodeoxynucleotides (ODN),
33 idate the mechanisms of immunostimulation by bacterial DNA and synthetic oligonucleotides, the effect
35 Although the pathways involved in sensing bacterial DNA and viral RNA are now well established, on
36 also resulted in the presence of contaminant bacterial DNA and yielded fewer reads from the known pat
37 ivated by un-methylated CpG motifs, found in bacterial DNA, and beta-glucans, found in the cell wall
38 olysaccharides, lipoproteins, flagellin, and bacterial DNA, and signaling through TLRs leads to the p
39 s, gram-negative (GN) and gram-positive (GP) bacterial DNA, and the antibiotic-resistance gene bla(TE
40 xcises phage lambda from the chromosome, the bacterial DNA architectural protein Fis recruits multipl
51 se studies thus identified a novel family of bacterial DNA-binding proteins, developed a model of Spo
52 hii Ptr2, a member of the Lrp/AsnC family of bacterial DNA-binding proteins, is an activator of its e
53 idylate kinase (TMK), an essential enzyme in bacterial DNA biosynthesis, is an attractive therapeutic
54 f 10(4) CFU/ml was correlated with increased bacterial DNA burden (P < 0.01), decreased community div
55 ture-independent indices of infection (total bacterial DNA burden and low bacterial community diversi
56 was ineffective with genomic double stranded bacterial DNA, but it allowed down to 16 amole detection
57 lex amplification and detection of viral and bacterial DNA by a flow-based chemiluminescence microarr
58 ype phages can randomly package and transfer bacterial DNA by a process called generalized transducti
72 Many studies have reported the presence of bacterial DNA contamination in commercial Taq DNA polyme
73 mmon to all four methods, and revealed trace bacterial DNA contamination in TFF-concentrated metageno
76 imulatory unmethylated CpG motifs present in bacterial DNA (CpG DNA) induce expression of cyclooxygen
83 s pathway is a disease-enhancing response to bacterial DNA damage inflicted by the host immune system
87 f the beta, beta', and sigma(70) subunits of bacterial DNA-dependent RNA polymerases (DdRp), combined
88 ssive oligodeoxynucleotides; 3) simulated by bacterial DNA derived from HKBA; and 4) abrogated by DNa
90 g of bacterial 16S rRNA genes to investigate bacterial DNA diversity in milk samples of mastitic and
91 s end joining (NHEJ) is a recently described bacterial DNA double-strand break (DSB) repair pathway t
92 pathway and PriA, suggesting a mechanism of bacterial DNA DSB repair involving the establishment of
95 A ligase D (PaeLigD) exemplifies a family of bacterial DNA end-joining proteins that consist of a lig
96 e-inducible GAL1 promoter joined to PvuII, a bacterial DNA endonuclease gene, are toxic to yeast cell
99 secretion samples were used for analysis of bacterial DNA for Porphyromonas gingivalis (Pg), Prevote
100 broad-range detection and identification of bacterial DNA from clinical specimens are a foundational
102 teins play a major role in the protection of bacterial DNA from damage by reactive oxygen species.
103 lunteers with liver cirrhosis, 50% contained bacterial DNA from Enterobactericaea, Clostridium leptum
104 n with specific primers and probes to detect bacterial DNA from several oral species and Chlamydia pn
109 ion of WDM for rapid, automated detection of bacterial DNA from whole blood may have an enormous impa
111 ome is facilitated by the directed motion of bacterial DNA generated during chromosome replication, i
112 tomyces sahachiroi AlkZ (previously Orf1), a bacterial DNA glycosylase that protects its host by exci
116 g (DXL) technology to obtain structures of a bacterial DNA glycosylase, MutM, interrogating undamaged
119 -2(1H)-ones, exemplified by 34, that inhibit bacterial DNA gyrase and topoisomerase IV and display po
120 g the GyrB/ParE ATP-binding sites located on bacterial DNA gyrase and topoisomerase IV and not utiliz
124 e and represent a new antibacterial class of bacterial DNA gyrase and topoisomerase IV inhibitors.
127 es are bifunctional antibiotics that inhibit bacterial DNA gyrase by preventing DNA binding to the en
131 arin natural product antibiotics that target bacterial DNA gyrase is assembled from tyrosine by nonri
132 A recent study has analysed the action of bacterial DNA gyrase on a single substrate DNA molecule,
133 Albicidin is a nanomolar inhibitor of the bacterial DNA gyrase with a strong activity against vari
134 A1 is a natural aminocoumarin that inhibits bacterial DNA gyrase, a member of the GHKL proteins supe
135 antibacterial agents that act by inhibiting bacterial DNA gyrase, a target of clinical significance.
138 intracellular bacteria, cytosolic sensing of bacterial DNA has also been implicated in eliciting immu
140 motifs (CpG ODN), which mimic the effects of bacterial DNA, have been shown to enhance type-1 cytokin
141 erised Geobacillus stearothermophilus Bad, a bacterial DNA helicase-nuclease with similarity to human
144 estimates the relative amounts of fungal and bacterial DNA in a sample in comparison to the endogenou
146 osomal DNA was used to measure the levels of bacterial DNA in blood samples drawn through the CVC in
148 been demonstrated by the presence of similar bacterial DNA in both prostatic secretion and subgingiva
151 6S rDNA PCR analysis reveals the presence of bacterial DNA in incubated blood samples but also in neg
153 recent reports suggest that the presence of bacterial DNA in peritoneal fluid in patients with cirrh
154 on analysis of the reassociation kinetics of bacterial DNA in soil, Gans et al. claimed that millions
155 e provide evidence, for the first time, that bacterial DNA in the context of heat-killed Brucella abo
158 The median value for the total amount of bacterial DNA in thrombi was 16 times higher than that f
161 glycan and double-stranded RNA, but not with bacterial DNA, indicating that Rip2 is downstream of TLR
162 ne-deoxyguanosine dinucleotides, which mimic bacterial DNA, induced hemophagocytosis only in IFN-gamm
163 pG oligodeoxynucleotides (ODNs), which mimic bacterial DNA, inhibit allergic airways disease and prom
165 The Cancer Genome Atlas (TCGA), we examined bacterial DNA integration into the human somatic genome.
166 foundation for future experiments to test if bacterial DNA integrations alter the transcription of th
167 will lead to the more frequent detection of bacterial DNA integrations in tumors that are in close p
169 at role these factors play in compacting the bacterial DNA into a distinct organelle-like entity, the
171 subsequent passive leakage of extracellular bacterial DNA into the host cell cytosol is sensed by th
172 ible for the generation and transport of the bacterial DNA into the host cell has resulted in the est
174 patient by a newly developed method in which bacterial DNA is amplified directly from sputum Gram-sta
176 rep Spin miniprep kit [Qiagen] and the urine bacterial DNA isolation kit [Norgen]) for the direct DNA
177 is to identify the structural components of bacterial DNA ligase that interact with NAD(+) and then
178 irement, and widespread existence in nature, bacterial DNA ligases appear to be valuable targets for
184 on 5 of a pyrimidine nucleotide, such as the bacterial DNA m(5)C methyltransferases, utilize their si
186 Mitochondrial DNA that shows similarities to bacterial DNA may be released after tissue damage and ac
187 -function mutations or transient exposure to bacterial DNA may drive persistent inflammatory mononucl
188 ch in guanine nucleotides and the integrated bacterial DNA may have complex transcript secondary stru
190 ing antibiotic stress and suggests targeting bacterial DNA methylation as a viable approach to enhanc
192 reasing number of studies have reported that bacterial DNA methylation has important functions beyond
193 e present a binning method that incorporates bacterial DNA methylation signatures, which are detected
194 man DNA methyltransferase 1 (hDNMT1) and the bacterial DNA methyltransferase (M.EcoRII) and that it i
196 Th1 phenotype, raising the possibility that bacterial DNA might play a role in the generation of pat
200 ondensed and became toroidal, similar to the bacterial DNA morphology seen during tetracycline treatm
201 nd examined for epithelial morphology, SIgA, bacterial DNA, nuclear factor-kappaB activation, neutrop
205 by unmethylated CpG-containing sequences in bacterial DNA or synthetic oligonucleotides (ODNs) in th
206 23, PMAP-36, and protegrin-1 to complex with bacterial DNA or synthetic RNA molecules and facilitate
207 romote NET formation, as did preparations of bacterial DNA, outer membrane proteins, and lipooligosac
208 expectation, animals receiving alum-GTF plus bacterial DNA (P. gingivalis in particular) demonstrated
209 mass spectrometry and normalized for mass of bacterial DNA per sample to exclude confounding by varyi
211 wist to this paradigm, a naturally occurring bacterial DNA polymerase I member isolated from Geobacil
213 capacity to inhibit the replication-specific bacterial DNA polymerase IIIC (pol IIIC) and the growth
215 ts of these reactions with several phage and bacterial DNA polymerases capable of strand-displacement
216 tes, consistent with replication by accurate bacterial DNA polymerases in the integrated prophage sta
217 archaeal FEN1 or the 5'-nuclease domains of bacterial DNA polymerases is a double-flap structure con
220 o interact with and facilitate import of the bacterial DNA-protein transport (T) complexes into the p
224 plasmid-borne RepA binding sites to inhibit bacterial DNA replication and delay host cell division w
225 on is also evident during the termination of bacterial DNA replication and during the induction of th
227 ilis, in contrast to the prevailing model of bacterial DNA replication based on Escherichia coli DnaA
231 rio extends our fundamental understanding of bacterial DNA replication initiation, and because of the
232 lethal infection in mice, demonstrating that bacterial DNA replication is inhibited during host-patho
237 We propose that DnaA serves to coordinate bacterial DNA replication with the onset of chromosome s
238 to those in eukaryal DNA replication than in bacterial DNA replication, but have some archaeal-specif
240 endosomes, TLR9 is activated by unmethylated bacterial DNA, resulting in proinflammatory cytokine sec
243 this study is to determine the expression of bacterial DNA sensors, including Toll-like receptor 9 (T
247 s from myeloperoxidase, serum amyloid A, and bacterial DNA, shifting the balance of pro- and anti-sur
255 nsive to CpG ODN but are fully responsive to bacterial DNA, thus implying that microbial recognition
256 bined this approach with quantitative PCR of bacterial DNA to normalize the amount of gene expression
262 DNA gyrase and topoisomerase IV control bacterial DNA topology by breaking DNA, passing duplex D
264 robiology, the most commonly used methods of bacterial DNA transfer are conjugation and electroporati
265 ng the viral DNA-packaging motor, beside the bacterial DNA translocases, that uses a revolving mechan
270 ng approach for the broad range detection of bacterial DNA using broad-range 16S rRNA gene hybrid cap
271 lli identified by Gram staining, we isolated bacterial DNA using spin columns (BC-C) and rapid water
272 etic readout of rolling circle products from bacterial DNA utilizing the dynamic properties of MNBs i
273 ve qPCR detection of the extracted S. aureus bacterial DNA was achieved with a detection limit of 5+/
274 were collected from children, and extracted bacterial DNA was amplified for the V4 region of the 16S
275 Among the 46 samples associated with PTB, bacterial DNA was amplified from all (16/16) of the cult
279 ization and microbial diversity on the skin, bacterial DNA was analyzed from swabs collected from les
287 cimens with no culture growth, the amount of bacterial DNA was greater than that in reagent and rinse
297 ment may be systematically contaminated with bacterial DNA, which appears to be sampled by metagenome
298 s were positive for spiroplasma or any other bacterial DNA, while control Spiroplasma mirum genomic D
299 larensis revealed striking colocalization of bacterial DNA with endogenous AIM2 and inflammasome adap
300 how that neighboring transgenic elements and bacterial DNA within the transgene cause profound silenc