ライフサイエンスコーパス: bacterial meningitis

1 human pathogen causing pneumonia, sepsis and bacterial meningitis.

2 ocedure and had community-acquired anaerobic bacterial meningitis.

3 e, and S aureus as the causative pathogen of bacterial meningitis.

4 e observed in patients with septic shock and bacterial meningitis.

5 as identified in 24 of 1025 episodes (2%) of bacterial meningitis.

6 BS) have further changed the epidemiology of bacterial meningitis.

7 ospinal fluid profile indistinguishable from bacterial meningitis.

8 reases neurologic sequelae in a rat model of bacterial meningitis.

9 ponses in CNS inflammatory diseases, such as bacterial meningitis.

10 ntravenous administration of ceftriaxone for bacterial meningitis.

11 th parenteral antibiotics, although few have bacterial meningitis.

12 understanding of the role of inflammation in bacterial meningitis.

13 rile convulsive status epilepticus had acute bacterial meningitis.

14 lammation in animal models and patients with bacterial meningitis.

15 meningitidis is the major causative agent of bacterial meningitis.

16 mproving outcome in subsets of patients with bacterial meningitis.

17 degrees C had a rate of 0.4% for bacteremia/bacterial meningitis.

18 herwise healthy and present early with acute bacterial meningitis.

19 We identified 26 children with bacterial meningitis.

20 idemiology during the past decade than acute bacterial meningitis.

21 h antimicrobial agents, in humans with acute bacterial meningitis.

22 st in developing novel strategies to prevent bacterial meningitis.

23 ory cascade leading to tissue destruction in bacterial meningitis.

24 Alzheimer's disease, multiple sclerosis and bacterial meningitis.

25 nsplants from 33 cadaveric donor livers with bacterial meningitis.

26 erity of neurological damage in experimental bacterial meningitis.

27 ain is a pivotal event in the progression of bacterial meningitis.

28 cids (EAA) from brain tissue of animals with bacterial meningitis.

29 ococcus pneumoniae, the most common cause of bacterial meningitis.

30 as of inflammation in multiple sclerosis and bacterial meningitis.

31 tment into the central nervous system during bacterial meningitis.

32 urologic sequelae, including deafness, after bacterial meningitis.

33 ating complement expression in this model of bacterial meningitis.

34 to contribute to intrathecal inflammation in bacterial meningitis.

35 In this study we explored the role of ROI in bacterial meningitis.

36 vide a therapeutic approach for treatment of bacterial meningitis.

37 and 98 cases (2.7%: 98/3644) were confirmed bacterial meningitis.

38 cterial infections, including 11 (0.7%) with bacterial meningitis.

39 Case fatality ratios of bacterial meningitis.

40 CSF) leakage is a risk factor for developing bacterial meningitis.

41 .0% [82/2762]) CSF samples were positive for bacterial meningitis.

42 ationwide cohort study of community-acquired bacterial meningitis.

43 nimal role in the early host response during bacterial meningitis.

44 e identified as significant risk factors for bacterial meningitis.

45 oniae (pneumococcus) is the primary cause of bacterial meningitis.

46 urella multocida is a rare cause of neonatal bacterial meningitis.

47 hree pathogens responsible for most cases of bacterial meningitis.

48 is is the most frequent and critical type of bacterial meningitis.

49 treatment and contributes to brain damage in bacterial meningitis.

50 those with fungal (13), arboviral (10), and bacterial meningitis (7).

51 th CNS infections and 16 were diagnosed with bacterial meningitis (8%).

52 Among those with childhood bacterial meningitis, 812 (32.0%) were diagnosed at youn

53 cus pneumoniae (SPN) is the leading cause of bacterial meningitis, a disease with high attributable m

54 treptococcus pneumoniae is the main cause of bacterial meningitis, a life-threating disease with a hi

55 ee most common pathogens accounting for most bacterial meningitis, a serious global infectious diseas

56 Acute bacterial meningitis (ABM) in adults residing in resourc

57 High mortality burden from Acute Bacterial Meningitis (ABM) in resource-poor settings has

58 In suspected acute bacterial meningitis (ABM), cerebral computerized tomogr

59 icenter observational study of children with bacterial meningitis, adjuvant corticosteroid therapy wa

60 Bacterial meningitis affects approximately 0.9 per 100 0

61 Brain injury due to bacterial meningitis affects multiple areas of the brain

62 from hospital-based sentinel surveillance of bacterial meningitis among children <5 years of age in T

63 H. influenzae type b remain associated with bacterial meningitis among children aged <5 years in Cot

64 to describe the epidemiology and etiology of bacterial meningitis among children less than 5 years in

65 95% confidence interval [CI], 3.1%-4.4%) had bacterial meningitis and 3174 (96.3%; 95% CI, 95.5%-96.9

66 CSF from 149 Malawian adults with bacterial meningitis and 39 controls were analyzed using

67 de key insight into the seasonal dynamics of bacterial meningitis and add to knowledge about the glob

68 criteria accurately differentiated TBM from bacterial meningitis and could be considered for use in

69 eurobehavioral performance was altered after bacterial meningitis and could be correlated with histol

70 ults and children with common types of acute bacterial meningitis and has been of proven value in the

71 s is the most common and aggressive cause of bacterial meningitis and induces a novel apoptosis-induc

72 Niamey, Niger, to determine risk factors for bacterial meningitis and invasive bacterial disease.

73 Neisseria meningitidis causes bacterial meningitis and is therefore responsible for co

74 reptococcus pneumoniae is the major cause of bacterial meningitis and it damages the hippocampus by i

75 not improve outcome in patients with severe bacterial meningitis and may even be harmful.

76 gender unexpectedly broad protection against bacterial meningitis and may provide a therapeutic targe

77 up B Streptococcus (GBS) is a major cause of bacterial meningitis and neurological morbidity in newbo

78 umoniae (pneumococcus) is a leading cause of bacterial meningitis and neurological sequelae in childr

79 een a dramatic reduction in the incidence of bacterial meningitis and of occult bacteremia since the

80 a diagnosis of malaria-slide-negative acute bacterial meningitis and other nonspecific encephalopath

81 In the prevaccine period, bacterial meningitis and pneumonia hospitalizations acco

82 hospital admission logbook were recorded for bacterial meningitis and pneumonia hospitalizations in c

83 eria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis globally.

84 Neisseria meningitidis is a leading cause of bacterial meningitis and sepsis worldwide and an occasio

85 Neisseria meningitidis is a major cause of bacterial meningitis and sepsis worldwide.

86 terial (for example, tuberculosis, syphilis, bacterial meningitis and sepsis), fungal (for example, c

87 ria meningitidis is a human pathogen causing bacterial meningitis and sepsis.

88 eria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis.

89 Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia in children and youn

90 meningitidis is one of the leading causes of bacterial meningitis and septicemia in children.

91 negative pathogenic bacteria responsible for bacterial meningitis and septicemia, and the sexually tr

92 transmitted infection gonorrhea and serious bacterial meningitis and septicemia, respectively.

93 Neisseria meningitidis causes bacterial meningitis and septicemia.

94 able diseases to determine the prevalence of bacterial meningitis and vaccine impact across the count

95 en serious conditions, such as bacteremia or bacterial meningitis, and minor illnesses.

96 umoniae remains a leading cause of pediatric bacterial meningitis, and nonvaccine serotypes may play

97 PCV10 introduction, pneumococcal meningitis, bacterial meningitis, and pneumonia hospitalizations dec

98 for the pathogenesis of brain edema in acute bacterial meningitis, and suggest that inhibition of AQP

99 the incidence and impact of endocarditis in bacterial meningitis are unknown.

100 Significant injury during bacterial meningitis arises from mechanisms of neuronal

101 s of a positive urinalysis result to exclude bacterial meningitis as a cause.

102 a has been implicated in the pathogenesis of bacterial meningitis as a potent mediator of inflammatio

103 We defined bacterial meningitis as the presence of H. influenzae, S

104 r 31, 2006, of 2780 children discharged with bacterial meningitis as their primary diagnosis from 27

105 We analyzed episodes of community-acquired bacterial meningitis associated with CSF leakage from a

106 old: to document the current epidemiology of bacterial meningitis at a tertiary care medical center a

107 -8 levels were observed within patients with bacterial meningitis at fever onset, which was not evide

108 Sahel region of West Africa has the highest bacterial meningitis attack and case fatality rate in th

109 important causes of community and nosocomial bacterial meningitis based on International Classificati

110 Of 2264 episodes of community-acquired bacterial meningitis between 2006 and 2018, 143 (6%) wer

111 ditis is an uncommon coexisting condition in bacterial meningitis but is associated with a high rate

112 examethasone should be used in patients with bacterial meningitis but stopped if Listeria monocytogen

113 Endocarditis may precede or complicate bacterial meningitis, but the incidence and impact of en

114 iability may contribute to susceptibility of bacterial meningitis, but which genes contribute to the

115 14 patients categorized as very low risk for bacterial meningitis by the Bacterial Meningitis Score,

116 thogen-specific meningitis case fatality and bacterial meningitis case data from surveillance studies

117 ningitidis serogroup A (NmA) among confirmed bacterial meningitis cases decreased from 254 (86.4%) du

118 We describe analysis of bacterial meningitis cases during 3 periods: pre-MACV (2

119 n was evaluated in culture-confirmed TBM and bacterial meningitis cases.

120 of bacteria accounted for 60% (3790/6286) of bacterial meningitis cases: Neisseria meningitidis (1350

121 Invasive bacterial meningitis caused by Neisseria meningitidis ca

122 Bacterial meningitis causes life-threatening infections

123 Community-acquired bacterial meningitis causes substantial morbidity and mo

124 ia meningitidis is one of the main agents of bacterial meningitis, causing substantial morbidity and

125 , or stool samples, including bacteremia and bacterial meningitis classified as IBIs.

126 those with normal IMs had bacteremia and/or bacterial meningitis compared with those with abnormal I

127 Bacterial meningitis continues to be a substantial cause

128 Vaccine-type bacterial meningitis continues to be common among childr

129 The rate of bacterial meningitis declined by 55% in the United State

130 in-8 in a temporal manner may indicate early bacterial meningitis development in neurosurgical patien

131 , a group of children with culture-confirmed bacterial meningitis, diagnosed between 2003 and 2009, w

132 Laboratories play critical roles in bacterial meningitis disease surveillance in the African

133 is was reported in two children: one case of bacterial meningitis due to Streptococcus pneumoniae in

134 0 for cerebral malaria and 7 per 100,000 for bacterial meningitis during the study period.

135 We describe bacterial meningitis epidemiology in these 5 countries i

136 Although bacterial meningitis epidemiology varied widely by count

137 Mortality from adult bacterial meningitis exceeds 50% in sub-Saharan Africa.

138 Half of the survivors of bacterial meningitis experience motor deficits, seizures

139 We describe the epidemiologic features of bacterial meningitis five years after the H. influenzae

140 to the Netherlands Reference Laboratory for Bacterial Meningitis from 1989 through 1997, were assess

141 trials undertaken in Blantyre investigating bacterial meningitis from 1990 to the current time and c

142 linic and laboratory features to distinguish bacterial meningitis from other diseases can be useful.

143 We developed the first bacterial meningitis global database by compiling monthl

144 exist that can protect against some types of bacterial meningitis (Haemophilus influenzae type b, Nei

145 Recurrent bacterial meningitis has been found to occur in about 5%

146 s, but its ability to differentiate TBM from bacterial meningitis has not been evaluated.

147 A substantial reduction in bacterial meningitis has occurred in the UK following su

148 Neisseria meningitidis, a causative agent of bacterial meningitis, has a relatively small repertoire

149 Rates of bacterial meningitis have declined in children, but not

150 The rates of bacterial meningitis have decreased since 1998, but the

151 gnificantly reduce mortality associated with bacterial meningitis; however, in children, studies reve

152 idis serogroup B (MnB) is a leading cause of bacterial meningitis; however, MnB is most commonly asso

153 that classifies patients at very low risk of bacterial meningitis if they lack all of the following c

154 n 1.8% of infants (2.4% of those tested) and bacterial meningitis in 0.5%.

155 Estimated incidence of bacterial meningitis in 2012 was 20 per 100,000 cases in

156 Adjuvant therapy with dexamethasone for bacterial meningitis in adults from an area with a high

157 a, where it emerged as an important cause of bacterial meningitis in adults.

158 us suis has emerged as an important cause of bacterial meningitis in adults.

159 Mortality from bacterial meningitis in African adults is significantly

160 study analysing data from clinical trials of bacterial meningitis in Blantyre, Malawi to investigate

161 ys) in adults with an admission diagnosis of bacterial meningitis in Blantyre, Malawi.

162 During reinforced surveillance of acute bacterial meningitis in Burkina Faso, meningococcal stra

163 A diagnosis of bacterial meningitis in childhood can lead to permanent

164 Bacterial meningitis in childhood is almost exclusively

165 A diagnosis of bacterial meningitis in childhood recorded in the Nation

166 A diagnosis of bacterial meningitis in childhood recorded in the Nation

167 In a Danish population, bacterial meningitis in childhood was associated with lo

168 ctioning in adult life among persons who had bacterial meningitis in childhood.

169 disease is no longer a major cause of acute bacterial meningitis in children but, instead, cases are

170 r the past several decades, the incidence of bacterial meningitis in children has decreased but there

171 neumoniae is the most common cause of severe bacterial meningitis in children, the elderly, and immun

172 tudy was to determine the impact of PCV10 on bacterial meningitis in hospitalized children <5 years o

173 a meningitidis is a major causative agent of bacterial meningitis in human beings, especially among y

174 mine the incidence, etiology, and outcome of bacterial meningitis in infants aged <90 days in the Uni

175 nce of dangerous infectious diseases such as bacterial meningitis in infants and adults.

176 Adults with community acquired bacterial meningitis in Malawi present with a severe cli

177 oli K1 is the leading cause of gram-negative bacterial meningitis in neonates.

178 Streptococcus (GBS) is the leading cause of bacterial meningitis in newborn infants.

179 We describe the epidemiology of bacterial meningitis in Niger from 2010 to 2018.

180 and Drug Administration received reports of bacterial meningitis in patients with cochlear implants

181 Bacterial meningitis in patients with CSF leakage has a

182 oups A and X are among the leading causes of bacterial meningitis in the African meningitis belt.

183 Spn was the most common cause of pediatric bacterial meningitis in the African region even after re

184 hort study of adults with community-acquired bacterial meningitis in the Netherlands from 2006 to 201

185 seria meningitidis has been a major cause of bacterial meningitis in the sub-Saharan region of Africa

186 On the basis of 248 cases of bacterial meningitis in the surveillance areas, the rate

187 e in meningitis due to H. influenzae type b, bacterial meningitis in the United States is now a disea

188 lus influenzae type b was the major cause of bacterial meningitis in the United States, and meningiti

189 nues to be the leading identifiable cause of bacterial meningitis in the USA, but with a significant

190 logy and molecular epidemiology of pediatric bacterial meningitis in Yaounde from 2010 to 2016.

191 The incidence of bacterial meningitis in young infants remains unchanged

192 multiple infectious complications, including bacterial meningitis, in adults.

193 The median age of persons with bacterial meningitis increased greatly, from 15 months i

194 Bacterial meningitis is a condition in which inflammatio

195 Bacterial meningitis is a disease worsened by neutrophil

196 Bacterial meningitis is a major cause of morbidity and m

197 Bacterial meningitis is a major cause of morbidity and m

198 Bacterial meningitis is a major cause of mortality among

199 Liver transplantation from donors with bacterial meningitis is a safe procedure provided both d

200 Bacterial meningitis is a serious health concern worldwi

201 Bacterial meningitis is a serious infection of the CNS t

202 Bacterial meningitis is a worldwide health problem, with

203 Bacterial meningitis is an infection of the thin membran

204 In sub-Saharan Africa, bacterial meningitis is common and is associated with a

205 tion of antibiotic treatment on suspicion of bacterial meningitis is important, but it is not enough

206 Acute bacterial meningitis is more common in resource-poor tha

207 Although the pathogenesis of bacterial meningitis is not completely understood, knowl

208 ningitis among young children, the burden of bacterial meningitis is now borne more by older adults.

209 high mortality and morbidity associated with bacterial meningitis is the incomplete understanding of

210 The risk of bacterial meningitis is very low (0.1%) in patients with

211 Acute bacterial meningitis is widely considered to result from

212 atients, and for patients with endocarditis, bacterial meningitis, lymphoma/leukemia, HIV/AIDS, inter

213 The use of cadaveric donors with bacterial meningitis may be associated with an increased

214 C5a was detected in all patients with bacterial meningitis (n = 9), in 6 of 18 patients with a

215 E. coli O18:K1:H7 as the archetypal neonatal bacterial meningitis (NBM) isolate RS218.

216 hia coli isolates from infants with neonatal bacterial meningitis (NBM), as submitted to the Netherla

217 control patients, and infants with neonatal bacterial meningitis (NBM), were analyzed and were compa

218 An estimated 4100 cases and 500 deaths from bacterial meningitis occurred annually in the United Sta

219 Bacterial meningitis occurs when bloodborne pathogens in

220 Among patients with community-acquired bacterial meningitis, odds of mortality increase markedl

221 occus pneumoniae is the most common cause of bacterial meningitis of high mortality and morbidity.

222 We identified 3188 patients with bacterial meningitis; of 3155 patients for whom outcome

223 to comprehensively assess seasonal trends in bacterial meningitis on a global scale.

224 nly significantly increased in patients with bacterial meningitis on the fourth day post fever.

225 on UK charity, whose child had suffered from bacterial meningitis or meningococcal septicaemia within

226 arditis (OR = 8.3; CI, 4.9-13.9; P < .0001), bacterial meningitis (OR = 3.8; CI, 1.2-12.0; P = .023),

227 and, potentially, with an increased risk of bacterial meningitis (OR=1.30; P=0.0024).

228 In 2016, Mali reported a bacterial meningitis outbreak consisting of 39 suspected

229 Historically, Nigeria has experienced large bacterial meningitis outbreaks with high mortality in ch

230 Long-term surveillance of bacterial meningitis outside of the epidemic "meningitis

231 differed (cryptococcal meningitis p=0.0014, bacterial meningitis p=0.0043, CNS tuberculosis p<0.0001

232 in the presence of endocarditis (P < 0.001), bacterial meningitis (P < 0.001), pyogenic arthritis (P

233 fference in cerebral malaria (p=0.98), acute bacterial meningitis (p=0.99), or all-cause coma (p=0.08

234 d morbidity remain high in adults with acute bacterial meningitis, particularly when due to Streptoco

235 13-2015, and 2016-2018, respectively, with a bacterial meningitis pathogen detected in 33.6% (294/876

236 y period, and proportion of specimens with a bacterial meningitis pathogen identified, by period, pat

237 a range of processes known to be involved in bacterial meningitis pathogenesis was examined.

238 e chain reaction; 22 (76%) were positive for bacterial meningitis pathogens, 16 (73%) of which were N

239 ailable for culture-free characterization of bacterial meningitis pathogens.

240 EBV was detected in 79 of 149 bacterial meningitis patients.

241 Pediatric bacterial meningitis (PBM) causes severe morbidity and m

242 Pediatric bacterial meningitis (PBM) remains an important cause of

243 HO), Cote d'Ivoire has implemented pediatric bacterial meningitis (PBM) surveillance at 2 sentinel ho

244 Nigeria to establish the burden of pediatric bacterial meningitis (PBM).

245 type b (Hib) is a leading cause of childhood bacterial meningitis, pneumonia, and other serious infec

246 leakage should be suspected in patients with bacterial meningitis presenting with liquorrhea, recurre

247 sitivity of a positive Gram stain result for bacterial meningitis ranges from 50% to 90%.

248 Neonatal bacterial meningitis remains a disease with unacceptable

249 Acute bacterial meningitis remains a major cause of childhood

250 Bacterial meningitis remains a major cause of morbidity

251 Bacterial meningitis remains a major disease affecting c

252 In sub-Saharan Africa, bacterial meningitis remains a significant public health

253 We analyzed data on cases of bacterial meningitis reported among residents in eight s

254 rosis, cerebral ischemia and hemorrhage, and bacterial meningitis respond to treatment with MMPIs.

255 Brain injury due to bacterial meningitis results in a high mortality rate an

256 To validate the Bacterial Meningitis Score in the era of widespread pneu

257 The Bacterial Meningitis Score may be helpful to guide clini

258 This large multicenter study validates the Bacterial Meningitis Score prediction rule in the era of

259 ery low risk for bacterial meningitis by the Bacterial Meningitis Score, only 2 had bacterial meningi

260 ly developed a clinical prediction rule, the Bacterial Meningitis Score, that classifies patients at

261 itivity and negative predictive value of the Bacterial Meningitis Score.

262 sease activity had a latitudinal trend, with bacterial meningitis seasons peaking during the winter m

263 y the Bacterial Meningitis Score, only 2 had bacterial meningitis (sensitivity, 98.3%; 95% CI, 94.2%-

264 isseria are obligate human pathogens causing bacterial meningitis, septicaemia and gonorrhoea.

265 Bacterial meningitis should be suspected if any of the f

266 ion, single-dose surgical prophylaxis, acute bacterial meningitis, spontaneous bacterial peritonitis,

267 o the major Gram-positive causative agent of bacterial meningitis, Streptococcus pneumoniae, and show

268 We describe findings from sentinel site bacterial meningitis surveillance in children <5 years o

269 ted sentinel site surveillance for pediatric bacterial meningitis surveillance.

270 ared with children admitted to hospital with bacterial meningitis symptoms but negative diagnosis.

271 f the inflammatory responses associated with bacterial meningitis that emphasize the need for early d

272 We conclude that in the treatment of severe bacterial meningitis, the application of moderate hypoth

273 e diagnosis of enteroviral meningitis versus bacterial meningitis, thereby resulting in timely and ap

274 In persons with community-acquired bacterial meningitis, three baseline clinical features o

275 omide could have a therapeutic role in acute bacterial meningitis through inhibition of IL-8-mediated

276 We documented bacterial meningitis trends among adults and children pr

277 ections (IBIs), defined as bacteremia and/or bacterial meningitis, using complete blood cell count pa

278 d Wales, the incidence of confirmed neonatal bacterial meningitis was 0.21 (n = 167; 95% CI, .18-.25)

279 Bacterial meningitis was confirmed in 21.4% (69/323) of

280 Bacterial meningitis was confirmed in 273 patients: 48%

281 via culture, latex, and/or rt-PCR; confirmed bacterial meningitis was defined by a positive result on

282 l impairment due to adult community-acquired bacterial meningitis was performed.

283 Postimplantation bacterial meningitis was strongly associated with the us

284 sociated with 23% (9-36) of cases, and acute bacterial meningitis was the cause of 10% (8-12) of case

285 lay an important role in the pathogenesis of bacterial meningitis, we examined whether functional pol

286 th Organization case definition of suspected bacterial meningitis were analyzed at the sentinel site

287 m these data, we estimate that 5755 cases of bacterial meningitis were caused by these five pathogens

288 Seven hundred and fifteen episodes of bacterial meningitis were evaluated.

289 total of 2548 episodes of community-acquired bacterial meningitis were evaluated.

290 Adults with community acquired bacterial meningitis were included if the CSF culture is

291 </=8 for <12 hours) with community-acquired bacterial meningitis were randomized.

292 ys prior to fever onset within patients with bacterial meningitis when compared with both aseptic and

293 Bacterial meningitis, which is caused mainly by Neisseri

294 ave dramatically altered the epidemiology of bacterial meningitis, while the methodology for culturin

295 hey treated 61 of the 63 cases of bacteremia/bacterial meningitis with antibiotics.

296 free diagnosis of these three major types of bacterial meningitis, with high sensitivity and specific

297 or the differential diagnosis of aseptic and bacterial meningitis within neurosurgical patients.

298 Neisseria meningitidis is a major cause of bacterial meningitis worldwide, especially in the Africa

299 of Neisseria meningitidis, a major cause of bacterial meningitis worldwide.

300 lts, strep throat, scarlet fever, pneumonia, bacterial meningitis, yeast infections, urinary tract in