ライフサイエンスコーパス: bacterial protein

1 acetylation can regulate the stability of a bacterial protein.

2 no acids (4B-4C loop) that are absent in the bacterial protein.

3 ch of which lacks sequence similarity to the bacterial protein.

4 sh the presentation of peptides derived from bacterial proteins.

5 s the bacteria and forms complexes with many bacterial proteins.

6 elated NAIP paralogs that recognize distinct bacterial proteins.

7 s been attributed to any of these ubiquitous bacterial proteins.

8 iques such as mass spectrometric analysis of bacterial proteins.

9 protein translocons, partially by recycling bacterial proteins.

10 f predicting the subcellular localization of bacterial proteins.

11 irreversibly denatures and precipitates many bacterial proteins.

12 rane pore (translocon) typically formed by 3 bacterial proteins.

13 , one of which is found in both archaeal and bacterial proteins.

14 suited for assigning mass spectral data from bacterial proteins.

15 poral localization and dynamics of different bacterial proteins.

16 n associated increased antibody responses to bacterial proteins.

17 tely after radiolabeling de novo-synthesized bacterial proteins.

18 ght and pI, and subcellular localizations of bacterial proteins.

19 ween input and output signalling elements in bacterial proteins.

20 's ability to cause aggregation of essential bacterial proteins.

21 me that carries out regulated degradation of bacterial proteins.

22 es the N-formyl group from newly synthesized bacterial proteins.

23 ed to target the structures of any essential bacterial proteins.

24 these systems are among the most scrutinized bacterial proteins.

25 , we similarly designed four other human and bacterial proteins.

26 this amount, 86% was proteinaceous, ~60% was bacterial protein, ~7% was soluble-free protein, ~15% wa

27 eveals TRIM21 as a superantigen analogous to bacterial protein A and suggests that an antibody bipola

28 n-based spindle, and it segregated phage and bacterial proteins according to function.

29 The collagen-binding bacterial proteins, Ace and Cna, are well characterized

30 At present, bacterial protein acetylation plays a prominent role in

31 ld, it is not surprising that the targets of bacterial protein acetyltransferases are very diverse, m

32 histone acetyltransferases, but non-histone bacterial protein acetytransferases have been identified

33 The DUF1094 family contains over 100 bacterial proteins, all containing a conserved CXC motif

34 rough the activation of bystander T cells by bacterial proteins, although these signals are enhanced

35 work characterizes a DGR that diversifies a bacterial protein and confirms the hypothesis that DGR-m

36 The high concentration of bacterial protein and the presence of ammonia and urea n

37 A streptococcus (GAS), cleaves both host and bacterial proteins and contributes importantly to the pa

38 istantly related to structures of additional bacterial proteins and may use a core beta-sheet within

39 tep that was optimized for enrichment of the bacterial proteins and peptides that are used for bacter

40 ycan extending beyond the external layers of bacterial proteins and polysaccharides.

41 SPOR domains are present in thousands of bacterial proteins and probably bind septal peptidoglyca

42 he highly conserved mammalian homolog of the bacterial protein, and it was found to be effective in p

43 will depend on the effectiveness with which bacterial proteins are able to activate bystander T cell

44 , providing valuable information about which bacterial proteins are actually recognized by the immune

45 wledge, this represents the first time these bacterial proteins are being reported, following treatme

46 These bacterial proteins are delivered to the host's molecular

47 acteria and it has been suggested that these bacterial proteins are involved in subversion of the ver

48 Several bacterial proteins are known to serve as receptors for P

49 Many bacterial proteins are localized to precise intracellula

50 to determine the subcellular localization of bacterial proteins are needed for the study of prokaryot

51 al, relatively little is known regarding how bacterial proteins are recognized and targeted for degra

52 These bacterial proteins are responsible for modulating eukary

53 Although the bacterial proteins are strikingly similar in sequence to

54 hrough the needle and pore channels, further bacterial proteins are translocated inside the host cell

55 ptides and requires the participation of the bacterial protein BacA.

56 akes it possible that the PDZ domain of this bacterial protein binds proteins in a manner which is al

57 umophila where they served as precursors for bacterial protein biosynthesis.

58 n the recently solved structure of a related bacterial protein, BsYetJ, altered the conductance (E207

59 g mechanism is similar to that of homologous bacterial proteins but without the requirement for "latc

60 any anti-infectives inhibit the synthesis of bacterial proteins, but none selectively inhibits their

61 ng sequence identity to either eukaryotic or bacterial proteins, but sharing homology with a cluster

62 ledge, we are reporting that a Gram-negative bacterial protein can activate CD36 as a pattern recogni

63 dratases (OhyAs) belong to a large family of bacterial proteins catalyzing the hydration or isomeriza

64 opic retinal expression of a light sensitive bacterial protein, channelrhodopsin-2, can restore neuro

65 When both methods are applied to bacterial protein coding sequences they both detect an e

66 The bacterial protein complex Mnx contains a multicopper oxi

67 in the 50S ribosomal unit and 28 additional bacterial protein complexes with known structure are alm

68 ensory modules for a wide range of plant and bacterial proteins, conferring blue light-dependent regu

69 antibody specific to RNA/DNA duplexes and a bacterial protein conjugated with a horseradish peroxida

70 Autotransporters (ATs) are a family of bacterial proteins containing a C-terminal beta-barrel-f

71 eukaryotic cells a large number of different bacterial proteins containing ankyrin repeat homology do

72 In total, 312 bacterial proteins could be identified in infected Arabi

73 after searching of the spectral data against bacterial protein databases.

74 e list of antibacterial products that target bacterial protein degradation and therefore may have uti

75 ntext, recent studies have demonstrated that bacterial protein degradation can trigger a precise resp

76 etion system (TTS), we demonstrate that this bacterial protein delivery system is required for intrac

77 p75 and p40 are the first probiotic bacterial proteins demonstrated to promote intestinal ep

78 Bacterial proteins destined for self-assembly and host-c

79 Recent work suggests that a bacterial protein detects changes in environmental tempe

80 ted resistance to apoptotic stimuli, but the bacterial protein directly involved in this process rema

81 ryotic defenses by enabling translocation of bacterial proteins directly into the cytoplasm of host c

82 g intracellular growth, C. burnetii delivers bacterial proteins directly into the host cytoplasm usin

83 application of this method to 3D imaging of bacterial protein distribution and neuron dendritic morp

84 The bacterial protein-disulfide isomerase DsbC is a homodime

85 , it is now clear that a number of different bacterial proteins do form filaments in vivo.

86 We have identified a new bacterial protein domain that we hypothesise binds to pe

87 Therefore, a single bacterial protein drives a multistep biochemical pathway

88 The bacterial protein DsbD transfers reductant from the cyto

89 cause eIF5A is a structural homologue of the bacterial protein EF-P, we propose that eIF5A/EF-P is a

90 Here, we describe a bacterial protein effector-carboxypeptidase G2 (CPG2) re

91 onserved host processes that are targeted by bacterial protein effectors injected into the host cell.

92 his apparatus enables the pathogen to inject bacterial proteins (effectors) into the cytosol of host

93 c-di-GMP-binding motif is present in diverse bacterial proteins exhibiting binding affinities ranging

94 the stability and solubility of proteins in bacterial protein expression systems and is increasingly

95 s is retarded by increasing densities of the bacterial proteins Fis and HU and by Nhp6A, indicating t

96 vity of microbial products revealed that the bacterial protein flagellin (FLA) stimulated strong alle

97 y, apoptosis inhibitory protein 5) binds the bacterial protein flagellin and assembles with NLRC4 to

98 This response requires expression of the bacterial protein flagellin.

99 to be activated in response to two distinct bacterial proteins, flagellin and PrgJ, a conserved comp

100 The bacterial proteins FlaX, A4-fla2, and YidX increased pro

101 educe their heme and so must rely on unknown bacterial proteins for electrons.

102 les of Ala, Asp, and Glu from the amoebal or bacterial protein fractions, respectively, indicating pa

103 We identified 473 human and 486 bacterial proteins from 18 different genera.

104 This transfer of bacterial proteins from migratory to local DCs results i

105 had a defect in their ability to chlorinate bacterial proteins from Pseudomonas aeruginosa metabolic

106 xport, benefits M. tuberculosis by diverting bacterial proteins from the antigen presentation pathway

107 motor FtsK50C, a construct derived from the bacterial protein FtsK that, in vitro, has a strong and

108 This review focuses on bacterial protein glycosylation and its impact in pathog

109 Allostery in bacterial proteins has thus been successfully exploited

110 esponse regulator Y (CheY), a 129-amino acid bacterial protein, has been shown previously to populate

111 Natural, anti-bacterial proteins have been discovered which have the p

112 Several bacterial proteins have been shown to polymerize into co

113 These bacterial proteins have biochemical activities that targ

114 data, surprisingly persistent collections of bacterial proteins have resisted functional annotation.

115 ifted completely from toroids to rods if the bacterial protein HU is present during condensation.

116 The low abundance of bacterial proteins in human serum during infection impos

117 ed domain architectures in support of naming bacterial proteins in RefSeq.

118 simple and general technique for imaging of bacterial proteins in situ by fluorescence microscopy.

119 ic NAIP proteins function to detect specific bacterial proteins in vivo.

120 xhibit noncovalent associations of PPS14 and bacterial protein, in contrast to soluble covalent conju

121 on as cytosolic immunoreceptors for specific bacterial proteins, including flagellin and the inner ro

122 Many bacterial proteins, including most secretory proteins, a

123 les (OMVs) that contain a number of secreted bacterial proteins, including phospholipases, alkaline p

124 Spatial organization of bacterial proteins influences many cellular processes, i

125 ovel mechanism of complement inhibition by a bacterial protein: inhibition of CRP surface binding and

126 This model of a bacterial protein inserting into host membranes to media

127 Both bacterial proteins interact with the RRS1 WRKY domain, a

128 ach other in the co-crystal structures of 33 bacterial protein interactions.

129 y for Listeria entry involves binding of the bacterial protein Internalin B to the host receptor tyro

130 mediated by the type III secretion (TTS) of bacterial proteins into eukaryotic hosts.

131 t of the human disease tuberculosis-delivers bacterial proteins into host cells during infection and

132 ot/Icm apparatus delivers over 300 different bacterial proteins into host cells during infection.

133 a pneumophila translocates a large number of bacterial proteins into host cells via the Dot/Icm type

134 are organelles with the capacity to deliver bacterial proteins into host cells, have been adapted to

135 retion (T3S) system, which transports select bacterial proteins into host cells.

136 cretion system called Dot/Icm to translocate bacterial proteins into host cells.

137 Pseudomonas syringae injects numerous bacterial proteins into host plant cells through a type

138 Delivery of bacterial proteins into mammalian cells by type III secr

139 based system to monitor the translocation of bacterial proteins into mammalian cells.

140 stems (T3SSs), which have evolved to deliver bacterial proteins into nucleated cells, are found in ma

141 mydia and its host and that translocation of bacterial proteins into the cytosol is developmentally d

142 ble for Legionnaires' disease, secretes ~300 bacterial proteins into the host cell cytosol.

143 lex between the integrin alpha7beta1 and the bacterial protein invasin.

144 well characterized ubiquitous and essential bacterial protein involved in almost all aspects of DNA

145 the Chlamydia homolog of the LcrE family of bacterial proteins involved in the regulation of type II

146 ThiS and ThiF are bacterial proteins involved in the synthesis of the thia

147 To identify bacterial proteins involved in the targeting of IcsA to

148 However, the bacterial proteins involved in this evasion are incomple

149 ng electrophoretic translocation through the bacterial protein ion channel alpha-hemolysin (alpha-HL)

150 The bacterial protein is here biased to move relatively free

151 responsible for the degradation of multiple bacterial proteins, is dynamically localized to specific

152 Because PE38 is a bacterial protein, it is highly immunogenic in patients

153 Sca2 (surface cell antigen 2) is the only bacterial protein known to promote both actin filament n

154 e-rich repeat protein family and the largest bacterial protein known.

155 We show here that, paradoxically, bacterial proteins known experimentally to elicit a prot

156 A family of extracellular bacterial proteins, known as resuscitation-promoting fac

157 regulome, and provides further evidence that bacterial protein levels do not always correlate directl

158 /NLRC4 inflammasome is activated by multiple bacterial protein ligands, including flagellin from the

159 onal differences between allelic variants of bacterial proteins likely contribute to pathoadaption to

160 ipoate ligase genes that are responsible for bacterial protein lipoylation.

161 LegU1 in mammalian cells, we identified the bacterial protein Lpg2160.

162 t subcellular localizations in Gram-negative bacterial proteins make use of standard protein represen

163 protein expression profiles establish which bacterial protein masses differ across samples and can b

164 ellular vaccines (Pa) composed of only a few bacterial proteins may be less efficacious because of va

165 nantly present in the signal sequence of the bacterial protein MgrB, a highly conserved regulator of

166 We propose that these bacterial proteins mimic molecular markers of self-surfa

167 Bacterial protein N-glycosylation and its application to

168 alpha-l-rhamnosyltransferase resembling only bacterial proteins of unknown function, and domain 3 is

169 Bacterial proteins often localize to distinct sites with

170 mycobacterial species to identify endogenous bacterial proteins or host proteins that interact with m

171 alyzing the temporal requirement of specific bacterial proteins or protein complexes in infection or

172 Crystal structures of the secreted bacterial protein Plu-MACPF and the human C8 alpha MACPF

173 that a stable heterotetramer composed of two bacterial proteins, Pnkp and Hen1, was able to repair tr

174 In this study, we describe the first bacterial protein posttranslational modification (PTM) b

175 cial in the processing and entry of viral or bacterial protein precursors and confer increased infect

176 er T-cell epitopes in PE38, a portion of the bacterial protein Pseudomonas exotoxin A which consists

177 responses to an immunotoxin derived from the bacterial protein Pseudomonas exotoxin A, as well as to

178 ced RITs that contain PE38, a portion of the bacterial protein Pseudomonas exotoxin A.

179 at mucosal surfaces, including the lung, the bacterial proteins recognized by Th17 cells are largely

180 A conserved globin domain of 15 bacterial proteins representing four structural families

181 ses specific for listeriolysin O, a secreted bacterial protein required for potency of L. monocytogen

182 The bacterial protein Rho triggers transcription termination

183 Measurement of bacterial protein S-nitrosylation directly implicates ni

184 al analysis has revealed that the Rickettsia bacterial protein Sca2--recently shown to be essential f

185 s of the Sec translocon, the major route for bacterial protein secretion from the cytoplasm.

186 Bacterial protein secretion is a highly orchestrated pro

187 The bulk of bacterial protein secretion occurs through the conserved

188 demonstrate that GBPs detect the presence of bacterial protein secretion systems as "patterns of path

189 Genes associated with other bacterial protein secretion systems were less common.

190 llow a distinct tempo, largely determined by bacterial protein secretion, and that CCR6-mediated bloo

191 Specifically, multiple virulent toxins from bacterial protein secretions are concurrently and natura

192 al and genomic data we have assessed a novel bacterial protein selected from a carbohydrate-related a

193 base of in silico fragment ions derived from bacterial protein sequences.

194 ilico fragment ions derived from hundreds of bacterial protein sequences.

195 rgely the result of the activity of a set of bacterial proteins (SopE, SopE2, and SopB) that, upon de

196 e, the hydrolyase domain of the bifunctional bacterial protein, SpoT, suggesting that AcpH is a membe

197 hosphatase conjugated to the highly specific bacterial protein streptavidin binds to biotinylated mac

198 IPAF]) responds to the cytosolic presence of bacterial proteins such as flagellin or the inner rod co

199 s the multiple roles exhibited by a range of bacterial proteins, such as glycolytic and other metabol

200 at iNKT cells can be activated directly by a bacterial protein superantigen independent of CD1d but a

201 oncotic macrophage cell death that requires bacterial protein synthesis and direct interaction of ba

202 mydiae with the host cell are dependent upon bacterial protein synthesis and presumably exposure of t

203 It inhibits bacterial protein synthesis by blocking elongation facto

204 n vitro, but metabolism is short-lived, with bacterial protein synthesis halting after a few hours.

205 assical antibiotic spectinomycin is a potent bacterial protein synthesis inhibitor, poor antimycobact

206 Auranofin's ability to suppress bacterial protein synthesis leads to significant reducti

207 did not appear to be dependent on sustained bacterial protein synthesis or on intact host actin, ves

208 Inhibition of bacterial protein synthesis reduced the antiapoptotic ef

209 duced apoptosis, indicating that the de novo bacterial protein synthesis was necessary for cell death

210 Furthermore, PNA-inhibition of bacterial protein synthesis was selective and did not ad

211 rwhelmingly TLR2 dependent, requires de novo bacterial protein synthesis, and is independent of intra

212 host endocytic and autophagic pathways, and bacterial protein synthesis, as the respective inhibitor

213 t as well as transcription and both host and bacterial protein synthesis, but not urease, NapA, VacA,

214 Thermorubin is a small-molecule inhibitor of bacterial protein synthesis, but relatively little is kn

215 and thiostrepton class, which block steps in bacterial protein synthesis, contain a trithiazolyl (tet

216 stant Staphylococcus aureus (MRSA), inhibits bacterial protein synthesis.

217 e clinic because of their ability to inhibit bacterial protein synthesis.

218 ation, RbfA and IF3 maintain the fidelity of bacterial protein synthesis.

219 antibiotics that block the initial steps of bacterial protein synthesis.

220 present a new series of compounds that block bacterial protein synthesis.

221 he TLR2 agonist activity is dependent on new bacterial protein synthesis.

222 propylamycin functions by interference with bacterial protein synthesis.

223 hetic pathways including cell wall, DNA, and bacterial protein synthesis.

224 ch by binding to ribosomal RNA (rRNA) affect bacterial protein synthesis.

225 acteria, including selective interference of bacterial protein synthesis.

226 e mechanisms and physiological importance of bacterial protein targeting.

227 ecialized secretion systems that translocate bacterial proteins, termed effectors, directly into host

228 ld into an elongated form that resembles the bacterial protein Tex.

229 ntron splicing factors in chloroplasts, in a bacterial protein that associates with ribosome precurso

230 oduct of the mfd gene) is a widely conserved bacterial protein that couples DNA repair with transcrip

231 on, we have characterized a hitherto unknown bacterial protein that is crucial for mediating an inter

232 ed mimics of gliadin epitopes and a parental bacterial protein that is naturally processed by antigen

233 X-ray crystal structures of tetrabrachion, a bacterial protein that is thermostable up to at least 40

234 Tex is a highly conserved bacterial protein that likely functions in a variety of

235 we determined the global fold of CbpA-R1, a bacterial protein that mediates the pathogenic effects o

236 oduct of the mfd gene) is a widely conserved bacterial protein that mediates transcription-coupled DN

237 ting of recombinant IgA1 protease (IgA1P), a bacterial protein that selectively cleaves human IgA1.

238 Systemic administration of flagellin, a bacterial protein that stimulates Toll-like receptor 5 (

239 sequent degradation of p53 are examples of a bacterial protein that subverts the p53 tumor suppressor

240 Our findings identify SINC as a novel bacterial protein that targets the nuclear envelope with

241 Staphylococcus aureus belong to a family of bacterial proteins that act as superantigens by activati

242 Bacterial proteins that are abnormally truncated due to

243 egy is antivirulence, with the aim to target bacterial proteins that are important in disease causati

244 ccines that target the functional regions of bacterial proteins that are involved in colonization and

245 Class III consists almost entirely of bacterial proteins that are lipooligo/polysaccharide alp

246 effectors), is found in numerous polymorphic bacterial proteins that are primarily located in the T6S

247 ulinum neurotoxins (BoNTs) are highly potent bacterial proteins that block neurotransmitter release a

248 Bacterial proteins that detoxify reactive oxygen species

249 ls that line the human intestinal tract, the bacterial proteins that enable this pathogen to survive

250 a self-propagating amyloid form and certain bacterial proteins that fold as amyloid at the cell surf

251 ns constitute a recently discovered class of bacterial proteins that form cytoskeletal filaments.

252 acetylation was recently discovered on many bacterial proteins that function in diverse cellular pro

253 widespread group of MocR/GabR-type chimeric bacterial proteins that have DNA-binding and aminotransf

254 bacteria secrete numerous effectors, namely, bacterial proteins that pervert host cell biology.

255 In contrast, some bacterial proteins that promote replication in amoebae r

256 The objective of this study was to identify bacterial proteins that promote the adherence of S. aure

257 SPOR domains are widely present in bacterial proteins that recognize cell-wall peptidoglyca

258 TraR and its homolog DksA are bacterial proteins that regulate transcription initiatio

259 the membrane targeting of a broad family of bacterial proteins, the patatin-like phospholipases.

260 retion (T3S) systems enable the injection of bacterial proteins through membrane barriers into host c

261 Priming for T cell memory against bacterial proteins through their inclusion in vaccine pr

262 tal structures have since confirmed multiple bacterial proteins to be homologues of eukaryotic tubuli

263 ed in conjunction with metabolic labeling of bacterial proteins to identify chlamydial proteins that

264 pathogenicity, as they provide the means for bacterial proteins to penetrate host-cell membranes and

265 ises due to a general increased tendency for bacterial proteins to self-assemble and form homomeric i

266 Sortase enzymes covalently attach specific bacterial proteins to the peptidoglycan cell wall and ar

267 h are predominantly based on the transfer of bacterial proteins to the target host cell, such as the

268 g toxins (PFTs) are the most common class of bacterial protein toxin and are important for bacterial

269 o ADP-ribosylating C3 exoenzyme (C3bot) is a bacterial protein toxin devoid of a cell-binding or -tra

270 Anthrax toxin is an A/B bacterial protein toxin which is composed of the enzymat

271 -dependent cytolysins (CDCs) are a family of bacterial protein toxins specifically targeting eukaryot

272 ter passenger domains but unique among known bacterial protein toxins.

273 sis factor alpha, interleukins 1 and 10) and bacterial proteins, toxins, and enzymes reported to be i

274 Here we found that a bacterial protein, transcription terminator Rho of Clost

275 timicrobial activity, inhibition of in vitro bacterial protein translation, and the effect of dimeriz

276 ws similarities to both eukaryotic Tom40 and bacterial protein translocases of the Omp85 family.

277 availability of reporter systems to monitor bacterial protein translocation into host cells.

278 ATPase motor protein plays a central role in bacterial protein transport by binding substrate protein

279 urther highlights the enormous plasticity of bacterial protein transport machineries.

280 ing and will be critical for elucidating the bacterial protein transport mechanism.

281 om our study, seven differentially expressed bacterial proteins (triacylglycerol lipase, N-acetylmura

282 The bacterial protein tyrosine phosphatase YopH is an essent

283 ral mechanism bear close similarities to the bacterial protein unfoldase ClpX.

284 antimicrobial activity in part by mediating bacterial protein unfolding and aggregation.

285 roposed for actin filament nucleation by the bacterial proteins VopL/F.

286 From a total of 1,153 quantified bacterial proteins, we thereby identified 72 surface exp

287 Differentially-expressed bacterial proteins were excised from the gels and subjec

288 Upon treatment with the plant extracts, bacterial proteins were extracted and resolved using den

289 Bacterial proteins were identified within minutes, direc

290 Prominent among oxidized bacterial proteins were those engaged in synthesis and t

291 Bacterial protein, which was strictly nondietary rather

292 In this study, we have identified >70 bacterial proteins, which represent fusions between the

293 The bacterial protein WhiD belongs to the Wbl family of iron

294 Because GroEL is a widely conserved bacterial protein with an essential function, we tested

295 Bacterial proteins with MCE domains were first described

296 ar dissociation constant (Kd) in a milieu of bacterial proteins with minimal sample preparation.

297 riability of CTLs and compare FtsZs to other bacterial proteins with tethered IDRs.

298 the biology of many bacterial pathogens are bacterial proteins with the capacity to modulate host ce

299 regulators indicated compatibility of these bacterial proteins with the eukaryotic transcriptional a

300 , and through the expression of libraries of bacterial proteins within model organisms such as yeast.