ライフサイエンスコーパス: bacterially

1 al cells and delineated a mechanism for this bacterially activated signaling.

2 teria transfer electrons to the dissolved or bacterially adsorbed U(VI) species formed after HUP diss

3 We investigated whether the bacterially captured FH becomes functionally enhanced an

4 cell organization and morphology, and (iii) bacterially catalyzed mineralization.

5 uggest that an endogenous 'lactate clock' in bacterially challenged M1 macrophages turns on gene expr

6 The repeated sequencing of bacterially-cloned fragments of psbA(ncr) from samples a

7 ties, but it is unclear whether an adjacent, bacterially conserved protein loop (residues 52-57) part

8 However, U52 and two bacterially conserved protein residues (F17 and R89) are

9 ts transfused (0.004%; 389 per million) were bacterially contaminated by active surveillance and resu

10 In all experiments, conducted in highly bacterially contaminated LB media, flux tests were run u

11 actions (STRs) resulting from transfusion of bacterially contaminated platelets are a major hazard of

12 Active and passive surveillance for bacterially contaminated platelets was performed over 7

13 the Pseudomonas syringae effector AvrRpt2 is bacterially delivered but is intact when AvrRpt2 is dire

14 We determined that bacterially delivered HopAF1 inhibits ethylene biosynthe

15 ce is nonredundant, we speculated that other bacterially derived Ags are priming these responses.

16 e cells upon continuous exposure to food and bacterially derived Ags.

17 sitive immunoassays, we identified host- and bacterially derived biomarkers correlated with periodont

18 s raises concerns over immunogenicity of the bacterially derived Cas9 protein.

19 Neutrophil migration against a bacterially derived chemoattractant (formyl-met-leu-phe,

20 The transporters mediate the egress of bacterially derived components, such as the NOD2 cognate

21 mmunity that is activated by host-derived or bacterially derived cyclic dinucleotides.

22 ns could explain, at least in part, why this bacterially derived exoenzyme effectively modulates this

23 Bacterially derived exotoxins kill eukaryotic cells by i

24 lated evidence demonstrates that PD involves bacterially derived factors and antigens that stimulate

25 Malassezia sympodialis, we demonstrated that bacterially derived flavohemoglobins are cytoplasmic pro

26 The ability of mFPR1 to detect bacterially derived formyl peptides indicates that this

27 han 2 decades ago and the finding that it is bacterially derived from daidzin, an isoflavone abundant

28 wed a group of yeasts to scavenge iron using bacterially derived genes.

29 wed a group of yeasts to scavenge iron using bacterially derived genes.

30 whether enzymatic depolymerization using the bacterially derived heparinases, given the structural un

31 ome of influenza virus infection using three bacterially derived immune-enhancing agents known for pr

32 or effects produced by Fkbp1a binding to its bacterially derived ligand, rapamycin.

33 ike receptors by facilitating recognition of bacterially derived lipids.

34 Bacterially derived lipopolysaccharide (LPS) stimulates

35 MAIT cells detect bacterially derived metabolites presented by the evoluti

36 whereas NLRs are activated by characteristic bacterially derived molecules, such as peptidoglycan, RN

37 enes activates CD8(+) T cells that recognize bacterially derived N-formyl methionine peptides in the

38 ls can exhibit cross-reactivity to different bacterially derived N-formylmethionine peptides.

39 des a template for the targeted expansion of bacterially derived natural products using the global me

40 Here, we demonstrate that bacterially derived NO enhances C. elegans longevity and

41 Bacterially derived Nod factor is critical in the establ

42 ity is determined by specific recognition of bacterially derived Nod factors by the cognate host rece

43 the conclusion that TLR activation requires bacterially derived PAMPs and that endogenously produced

44 vity to several caspases and to at least one bacterially derived pathologic protease.

45 doglycan recognition protein 1 (PGLYRP1) and bacterially derived peptidoglycan that constitute a pote

46 Bacterially derived phospholipids significantly increase

47 Furthermore, the recent discovery of a bacterially derived programmable nuclease termed cluster

48 econstituted in lipid bilayers revealed that bacterially derived PSA, called colominic acid, prolonge

49 inoculation with amyloid fibrils formed from bacterially derived recombinant prion protein.

50 More recently, PMCA techniques using bacterially derived recombinant PrP (rPrP) in the presen

51 This work serves as a proof-of-concept for bacterially derived SimCells (Simple Cells), which conta

52 Emerging evidence suggests novel roles for bacterially derived vitamin K forms known as menaquinone

53 Lipopolysaccharide (LPS) is a bacterially-derived endotoxin that elicits a strong proi

54 d organic nitrogen sources were dominated by bacterially-derived nitrogen and important contributions

55 and progression may be linked to exogenous, bacterially-derived, antigenic molecules, mimicking mamm

56 id generation of UbcH5 ~ Ub(n) may allow for bacterially directed modification of eukaryotic target p

57 al degradation of ciliate-derived biomass in bacterially dominated ecosystems.

58 f host immunity when experimentally treating bacterially driven cancer, leading us to test whether ba

59 ntic infections and periodontal diseases are bacterially driven diseases that are caused by dysbiotic

60 may inhibit colon carcinogenesis by reducing bacterially driven inflammation.

61 Smokers are at high risk for 2 bacterially driven oral diseases: peri-implant mucositis

62 Bacterially driven reactions such as ureolysis can induc

63 n secretion machines have evolved to deliver bacterially encoded effector proteins into eukaryotic ce

64 gens utilize complex nanomachines to deliver bacterially encoded effector proteins into target eukary

65 PriM is the first bacterially encoded factor to be described that can inte

66 ile there is strong evidence that DrrA, as a bacterially encoded GDP/GTP exchange factor, contributes

67 the Rho-family GTPases Cdc42 and Rac1 by the bacterially encoded GEF SopE and the GAP SptP, which exe

68 e as a paradigm for the examination of other bacterially encoded molecular machines.

69 study to identify a nuclear translocation of bacterially encoded protein by E. chaffeensis and to ide

70 systems have specifically evolved to deliver bacterially encoded proteins into target eukaryotic cell

71 of these intimin types binds to its cognate, bacterially encoded receptor (called Tir for translocate

72 ia are not easily culturable, access to many bacterially encoded secondary metabolites will be depend

73 stent with that assertion, we show here that bacterially encoded Stx efficiently kills the bacteriovo

74 t express the adhesin intimin and insert the bacterially encoded translocated intimin receptor Tir in

75 hile investigating the mechanisms underlying bacterially enhanced virion thermal stability, we identi

76 t of multiple glycosylation modifications to bacterially expressed (bare) protein scaffolds, allowing

77 the attachment of multiple modifications to bacterially expressed (bare) protein scaffolds: this app

78 ulate PABP cleavage in uninfected cells, and bacterially expressed 3C cleaved recombinant PABP in vit

79 nine at Ser-205 was synthesized and fused to bacterially expressed AANAT(30-199) using expressed prot

80 Using bacterially expressed acetylated-alphaS (NTAc-alphaS) an

81 coimmunoprecipitation of intracellularly and bacterially expressed and endogenous proteins.

82 teraction was confirmed both in vitro, using bacterially expressed and in vitro translated proteins,

83 actor 9 (FA9), mouse Notch1, and Notch2 were bacterially expressed and purified by reverse phase HPLC

84 Bacterially expressed and purified GRP58 increased the M

85 port the properties and characteristics of a bacterially expressed and purified GST-MDA-7 fusion prot

86 y with V(1) when expressed in yeast, but the bacterially expressed and purified H-CT domain inhibits

87 Bacterially expressed and purified NC mutant and N prote

88 The ability of purified 2A(pro) to cleave bacterially expressed and purified Nup62 demonstrated th

89 Modified proteins were bacterially expressed and purified.

90 Here we describe a recombinant, bacterially expressed antigen equivalent to structural d

91 od was applied to introduce (18)O label into bacterially expressed Aurora A kinase phosphorylation si

92 Bacterially expressed b121a/b122a were partially folded

93 All five Bcl-xL antibodies recognized bacterially expressed Bcl-xL, but not Bcl-2, whereas an

94 onfirmed by in vitro pull-down analysis with bacterially expressed beta-TrCP.

95 mice and that this bone loss depends on the bacterially expressed BspA protein.

96 A bacterially expressed C-terminal domain of LIN-14 was us

97 city, processivity, and kinetic mechanism of bacterially expressed Caenorhabditis elegans PRMT5 (cPRM

98 Here, we mechanically extended bacterially expressed Cas substrate domain protein (CasS

99 Bacterially expressed CCT5 chaperonin subunits, which fo

100 HuPON1 and bacterially expressed chimeric recombinant PON1s (G2E6 a

101 Bacterially expressed Chz1 forms a heterotrimer with H2A

102 We have also utilized bacterially expressed coilin fragments in order to map t

103 Purified, bacterially expressed CYP2E1(Delta3-29) is ubiquitylated

104 ction of a therapeutic vaccine consisting of bacterially expressed cytoplasmic domains of human AChR

105 , as in Caenorhabditis elegans, ingestion of bacterially expressed double-stranded RNA can inhibit ge

106 ecombinantly produced in Sf9 insect cells, a bacterially expressed EGF repeat from mouse Notch2 modif

107 fic activity and substrate preference of the bacterially expressed enzyme closely mimic those of the

108 sient and were not previously detected using bacterially expressed exon-1 protein.

109 e CAR proteins are able to interact with the bacterially expressed extracellular domain of CAR.

110 ber bundles that had been reconstituted with bacterially expressed fast skeletal muscle recombinant T

111 vitro methylation assays using PsLSMT and a bacterially expressed form of gamma-TMT from Perilla fru

112 ific differences between the NMR spectrum of bacterially expressed full-length tail and the sum of th

113 were examined in sedimentation assays using bacterially expressed fusion proteins and polymerized ac

114 excitatory capacity exceeding that of other bacterially expressed fusion proteins.

115 n binding were found for mutations made in a bacterially expressed GAF-A/B plus catalytic domain cons

116 Bacterially expressed glutathione S-transferase (GST)-Sm

117 e we characterize methylation catalyzed by a bacterially expressed GST-tagged human PRMT7 fusion prot

118 itro disassembly and reassembly system using bacterially expressed HBV capsids.

119 s analyses of binding in vitro using native, bacterially expressed HDAg have been hampered by a lack

120 Previous in vitro binding experiments using bacterially expressed HDAg showed that the formation of

121 was evaluated by vaccination with the single bacterially expressed homolog, rAg2/Pra, or rPrp2 in com

122 and PC myosin reconstituted with recombinant bacterially expressed human cardiac RLC (PC(recon)).

123 Bacterially expressed human P450c17 was phosphorylated b

124 ro phosphorylation assay was developed using bacterially expressed IE62-maltose binding protein fusio

125 suggest that a subunit vaccine incorporating bacterially expressed IMV- and EEV-specific proteins can

126 holoenzyme were very similar to those of the bacterially expressed individual GAF-A or GAF-A/B domain

127 K1 was able to support the ubiquitination of bacterially expressed IRS1 N-terminal fragment by CRL7 b

128 analyzed for their ability to interact with bacterially expressed JCV N protein.

129 Our bacterially expressed KIF1A construct, dimerized via a k

130 ated fibres were generated in vitro from the bacterially expressed labelled prion protein.

131 Thus, delipidation is critical for bacterially expressed lipid-binding proteins.

132 Bacterially expressed LOV domains bind flavin mononucleo

133 A bacterially expressed MAP65-3 protein was able to establ

134 Bacterially expressed MNV 3CL Pro was sufficient to medi

135 st studies to date have used MOG peptides or bacterially expressed MOG, neither of which contain the

136 previously shown that i.m. administration of bacterially expressed murine histidyl-tRNA synthetase (H

137 Further studies of bacterially expressed mutant enzymes revealed that GK(A4

138 or disrupted by a point mutation (L47A), the bacterially expressed mutant protein sediments as a mono

139 Bacterially expressed mutants were evaluated in detergen

140 A to a conventionally developed ELISA, using bacterially expressed N protein, and to the immunofluore

141 pigmentosum (XP) disease, a series of stable bacterially expressed N- and C-terminal fragments were d

142 tudy the structure of F-actin decorated with bacterially expressed N-terminal cMyBP-C fragments.

143 The bacterially expressed NPG1 bound three isoforms of Arabi

144 We describe two crystal structures of bacterially expressed OmCI: one binding a C16 fatty acid

145 Incubation of bacterially expressed or in vitro-translated Nup98 with

146 le-molecule fluorescence assay, we show that bacterially expressed OSM-3 in solution does not move pr

147 endent acetylation similar to that seen with bacterially expressed p53.

148 The speed and lower manufacturing cost of bacterially expressed PEGylated antibody fragments could

149 R5 to inhibit gp120 association, and C52L, a bacterially expressed peptide inhibitor of gp41-mediated

150 Here, we report the design of a bacterially expressed polypeptide that mimics a H5 HA st

151 a cDNA expression library was screened with bacterially expressed PPARalpha.

152 Crystallization of the bacterially expressed protein yielded two different crys

153 inal 35 amino acids of HDAg yields a native, bacterially expressed protein, HDAg-160, that specifical

154 Surface plasmon resonance using bacterially expressed proteins demonstrated that Noxa bi

155 Bacterially expressed proteins used in NMR studies lack

156 Epitope mapping with mammalian and bacterially expressed proteins, as well as synthetic pep

157 Gel shift assays using a bacterially expressed PUM2 RNA binding domain showed spe

158 Bacterially expressed rat PSP binds PtdIns(3,4)P(2) with

159 The bacterially expressed recombinant AtABHD11 hydrolyzed ly

160 Bacterially expressed recombinant CK2, however, showed v

161 and slightly greater seroreactivity than the bacterially expressed recombinant Cts1.

162 an be generated solely from highly purified, bacterially expressed recombinant hamster prion protein

163 structure of the extracellular domain of the bacterially expressed recombinant human protein, residue

164 use prions can be produced from a mixture of bacterially expressed recombinant prion protein (recPrP)

165 report that an infectious prion formed with bacterially expressed recombinant prion protein plus syn

166 in-like domain of titin, was introduced in a bacterially expressed recombinant protein fragment and b

167 and its enzymatic activity was confirmed in bacterially expressed recombinant protein.

168 infectious prion can be formed de novo with bacterially expressed recombinant PrP (rPrP) remains to

169 Here we show that bacterially expressed recombinant SMB (rSMB) can be refo

170 Furthermore, bacterially expressed recombinant TIE protein was shown

171 infectious prion can be formed de novo with bacterially expressed rPrP.

172 Bacterially expressed S(1)-, S(2)-, and S(3)-RNases are

173 S(3)-RNase is degraded as efficiently as the bacterially expressed S-RNases.

174 Here we report the crystal structure of the bacterially expressed SBV nucleoprotein to a 3.06-A reso

175 Bacterially expressed Scm3 binds directly to and reconst

176 Bacterially expressed SCPL-1 proteins have phosphatase a

177 Bacterially expressed Sfrs1 protein bound to B16-FTIII-M

178 protein interaction and RNA binding by using bacterially expressed Sin Nombre virus N protein.

179 Here, we characterize a bacterially expressed soluble protein, ECD1-CRFR2beta, c

180 In vitro enzyme analysis of bacterially expressed SSU-1 demonstrates sulfotransferas

181 onance-energy-transfer-based assay that uses bacterially expressed substrates for the rapid and quant

182 The bacterially expressed SYNCRIP was also able to bind to t

183 Purified, bacterially expressed Tat-c-Myb DBD and Tat-GR(554-777)

184 Nevertheless, bacterially expressed TbPRMT7 exhibits robust methyltran

185 have described for the first time domains of bacterially expressed Tetrahymena TERT that interacted d

186 Bacterially expressed TgPhyA protein can prolyl hydroxyl

187 we report an effective method for purifying bacterially expressed Tm as alpha.beta dimers using a cl

188 Using a series of bacterially expressed truncated versions of PICBP, four

189 d the transport properties and regulation of bacterially expressed UCP1, -2, and -3 reconstituted in

190 transferase (GST) pulldown experiments using bacterially expressed UL44 and UL84 confirmed these resu

191 zed conditions of isolation and refolding of bacterially expressed uncoupling proteins and reexamined

192 The bacterially expressed unphosphorylated SLIP1-SLBP comple

193 In addition, a complex containing bacterially expressed Vhs and a glutathione S-transferas

194 ed in the published crystal structure of the bacterially expressed VLP that appear to clamp the penta

195 mbled yVLPs compared with in vitro assembled bacterially expressed VLPs as monitored by increased the

196 Bacterially expressed VP3-CTD exhibited 2',5'-PDE activi

197 d I393M) also restored heterodimerization of bacterially expressed W401A subunits.

198 edicted EF-hands are functional, we purified bacterially expressed wild-type DC3 and analyzed its cal

199 Finally, bacterially expressed yeast Tdp1p is able to remove a pe

200 imeric Klp61F motor domains were engineered, bacterially expressed, and purified to test this idea.

201 nd both S28 and S29 using purified virus and bacterially expressed, his-tagged S28 and S29 proteins.

202 and mutant P450 oxidoreductase proteins were bacterially expressed, purified, and assayed for cytochr

203 The affinity matrix comprises a bacterially expressed, recombinant protein, the TOG1/2 d

204 In this study, we employed two bacterially expressed, soluble derivatives of NS5A to pr

205 soluble catalytic domain of human CYPOR was bacterially expressed.

206 codes a 197 amino acid polypeptide which was bacterially-expressed and purified for in vitro assays.

207 ongoing EAMG by intraperitoneal injection of bacterially-expressed human muscle AChR constructs.

208 Use of a mixture of bacterially-expressed human muscle AChR cytoplasmic doma

209 new means of identifying commonly occurring bacterially fermented alcoholic beverages worldwide, inc

210 The bacterially-formed nano-crystals prove effective in the

211 us influenzae (NTHi) is the primary cause of bacterially induced acute exacerbations of chronic obstr

212 Bacterially induced bone infections often result in sign

213 ng that lymphocytes were required to prevent bacterially induced cancer at this site.

214 Previously discovered mechanisms of bacterially induced cell death are predominantly based o

215 Bacterially induced cell death in human lymphocytes is a

216 mmed necrosis (necroptosis), but its role in bacterially induced cell death is poorly understood.

217 Periodontitis is a bacterially induced chronic inflammatory disease that de

218 Chronic adult periodontitis is a bacterially induced chronic inflammatory disease that de

219 was correlated with their ability to reduce bacterially induced inflammatory bowel disease.

220 Periodontitis, a bacterially induced inflammatory disease that leads to t

221 at this tachykinin can significantly elevate bacterially induced inflammatory prostanoid production b

222 s of interleukin (IL)-12 family cytokines in bacterially induced intestinal inflammation.

223 of primary rat middle ear mucosal explants, bacterially induced mucosal growth was blocked by the Ra

224 activation of JNK is a critical pathway for bacterially induced mucosal hyperplasia during otitis me

225 tantly, engagement of SIRL-1 does not affect bacterially induced production of reactive oxygen specie

226 Furthermore, bacterially induced reduction of methyl-donor availabili

227 Bacterially induced ROS causes oxidative inactivation of

228 nucleoside diphosphate kinase (Ndk) mediates bacterially induced toxicity against eukaryotic cells.

229 We show that this reversal coincides with bacterially induced wetting transitions and that flagell

230 nd messenger, can trigger innate immunity in bacterially infected animal cells and is involved in dev

231 Exfoliation is used as a mechanism to remove bacterially infected cells from the body.

232 reased concentration of hydrogen peroxide in bacterially infected glutathione peroxidase 1 macrophage

233 ion to induce intestinal injury; and iii) in bacterially infected IEC-6 cells in vitro.

234 cts of recombinant ACE2 when administered to bacterially infected mouse lungs following an initial in

235 Recent evidence demonstrates that bacterially infected osteoblasts secrete chemokines and

236 Although phosphates significantly influence bacterially mediated as well as iron oxyhydroxide mediat

237 Periodontal disease is a bacterially mediated chronic inflammatory disease that r

238 large database shows a marked change in the bacterially mediated fractionation of seawater sulphate

239 ioplankton, in line with the hypothesis that bacterially mediated PA transformation accounts for an i

240 Bacterially mediated secretion also involved activation

241 Bacterially mediated Tetrahymena killing was blocked by

242 te reduction and sulphide oxidation, largely bacterially mediated.

243 now been shown to be irreversibly blocked by bacterially-mediated acetylation, beta-elimination, and

244 Correlation analyses revealed that the bacterially-mediated increase in shoot fresh weight is r

245 ed state as supported by increased levels of bacterially modified amino acids and creatine metabolite

246 NKT cells were decreased in coexposed versus bacterially monoinfected bladders.

247 of an RNA-seq analysis workflow, easy-to-use bacterially oriented workflow applications to combine mu

248 Both proteins are frequent contaminants of bacterially overexpressed proteins which might have been

249 Bpa), was biosynthetically incorporated into bacterially prepared recombinant Sup(1-61)-GFP, containi

250 Bacteriocins, which are bacterially produced antimicrobial peptide products, are

251 Here we demonstrate catalytic activity of bacterially produced Arabidopsis Plsp1.

252 produced epinephrine and norepinephrine, and bacterially produced autoinducer 3 (AI-3), through two-c

253 anobactin structurally more similar to other bacterially produced bactins and siderophores and sugges

254 splay an escape response that is mediated by bacterially produced cues.

255 Various bacterially produced factors are essential for successfu

256 easing agonist) or adiponectin (10 microg/ml bacterially produced full-length adiponectin).

257 his study, we report the identification of a bacterially produced inhibitor of rosettes (IOR-1) as we

258 This study reveals that multiple bacterially produced lipids converge to activate, enhanc

259 At nanomolar concentrations, bacterially produced mCTRP2 rapidly induced phosphorylat

260 Furthermore, bacterially produced nanobody-RING fusion proteins elect

261 hat in vitro studies reliant on recombinant, bacterially produced Notch TMD should be performed with

262 ared the functionality and immunogenicity of bacterially produced oligomeric or monomeric HA1 protein

263 Results suggest that bacterially produced organic matter can play a role in s

264 properties from VLPs assembled in vitro from bacterially produced pentamers.

265 fungal mutualism is chemically mediated by a bacterially produced polyunsaturated peroxide.

266 Trimerization of the bacterially produced protein appears to be an artifact t

267 The approximately 34.5-kDa bacterially produced protein specifically catalyzed the

268 Previous investigations with a bacterially produced protein suggested that VE-cadherin

269 The ca. 63 kDa bacterially produced recombinant protein, designated L.

270 We here report that one of the main bacterially produced SCFAs, propionate, activates ileal

271 Here we identify GPR43, a receptor for bacterially produced short-chain fatty acids (SCFAs), as

272 Because bacterially produced siRNAs contain multiple sequences a

273 e initiation of rosette development requires bacterially produced small molecules.

274 our laboratories isolated and synthesized a bacterially produced sulfonolipid that induces S. rosett

275 These data suggest that the bacterially produced tetrameric ASA can be used as an an

276 release of exosomes that serve as decoys for bacterially produced toxins.

277 ssays, and that this selection bias requires bacterially produced tyramine and host octopamine signal

278 Bacterially produced tyramine is probably converted to o

279 The bacterially produced unglycosylated G protein could be d

280 This study suggests that bacterially produced unglycosylated G protein could be d

281 Therefore, bacterially produced unglycosylated G protein holds prom

282 ytocyanin-like domain from GhPLA1, which was bacterially produced, also promoted SE, indicating that

283 ponded to the late-eluting compound that was bacterially produced.

284 nhancement and algal death are driven by the bacterially-produced phytohormone indole-3-acetic acid.

285 Bacterially-produced small molecules exert profound infl

286 Using bacterially purified ATM truncation mutants and in vitro

287 Bacterially purified Bcr and TSG101 also bind, suggestin

288 In vitro binding studies with bacterially purified RNA Pol III proteins demonstrate th

289 B cells expressing self-reactive and broadly bacterially reactive antibodies were removed from the re

290 I IFN response due to cytosolic detection of bacterially secreted c-di-AMP.

291 and demonstrate high sensitivity to multiple bacterially-secreted chemoattractants.

292 or macrophages and promotes the migration of bacterially stimulated dendritic cells.

293 GLP-1-dependent checkpoint that senses food (bacterially)-supplied nucleotide levels, arresting repro

294 to be responsible for the absorption of the bacterially synthesized biotin and pantothenic acid in t

295 hat are capable of absorbing a number of the bacterially synthesized vitamins (thiamin, folate, bioti

296 n this study, we assessed the suitability of bacterially synthesized zinc- and cobalt-doped magnetite

297 ells (Tregs) to limit disease progression in bacterially triggered fibrosis exacerbation has not been

298 ious studies suggest that Tregs can suppress bacterially triggered intestinal inflammation and respon

299 ility of CD4(+)CD25(+) T(R) cells to inhibit bacterially triggered intestinal inflammation.

300 Microbacterium nematophilum identified bus (bacterially unswollen) genes that also affect surface ch