ライフサイエンスコーパス: basal level

1 lated by a ketogenic diet, which lowered HNE basal level.

2 sults in the maintenance of acetylation at a basal level.

3 e present in the general public, even at the basal level.

4 RK5(flox/flox)/Lck-Cre T cells remained at a basal level.

5 tores nuclear accumulation of NF-kappaB to a basal level.

6 m (AEC-CM) enhanced AM SOCS3 secretion above basal levels.

7 nal kinase (JNK) phosphorylation remained at basal levels.

8 R) in the cytosol, limiting STAR activity to basal levels.

9 ls, ryanodine receptors and phospholamban to basal levels.

10 ely, maintained eIF2alpha phosphorylation at basal levels.

11 , including labile iron pools at endogenous, basal levels.

12 romoted an increase to approximately 5-times basal levels.

13 urn of autophagosomes and UPR markers toward basal levels.

14 e, and by 8 days the expression reached near basal levels.

15 d longer spacers reducing transactivation to basal levels.

16 ogy reverted the FasL-associated motility to basal levels.

17 TG mice exhibit a hypertrophic phenotype at basal levels.

18 tory [Ca(2+)](i) ceases when glucose is at a basal levels.

19 er increases surface GluA1 beyond the higher basal levels.

20 copper pools in living cells at endogenous, basal levels.

21 promoting restoration of the Nrf2 protein to basal levels.

22 or primary lung fibroblasts with lower HO-1 basal levels.

23 ted the opposite pattern with no or very low basal levels.

24 /NMDAR ratio and NMDAR decay kinetics to the basal levels.

25 n the obese or normal-weight pregnant women (basal levels: 13.66 +/- 5.88 vs. 19.03 +/- 4.15 vs. 15.6

26 determined by flow cytometry and returned to basal levels 5 weeks after CUS.

27 apses within this projection returned to the basal levels, accompanied by a return of the AMPAR/NMDAR

28 p=0.003, p=0.000), and did not return to the basal level after extinction training (p=0.025, p=0.000)

29 ar exposure times (3-6 h), which falls below basal levels after prolonged shear exposure (12-48 h).

30 G2 hepatoblastoma cells expressing low DNMT1 basal levels also possessed a high self-renewal, irrespe

31 Notably, clamping CaMKII activity to basal levels ameliorates but does not completely offset

32 from ASMase-knock-out mice exhibit increased basal level and activity of CtsB as well as its in vitro

33 rophage transcriptional programs both at the basal level and after IFN-gamma activation.

34 Autophagy occurs at a basal level and can be induced by various types of stres

35 ession resulted in two levels of PH-Tau: low basal level and higher upon induction (4% and 14% of the

36 nuclear translocation of p65, and suppressed basal level and TNF-alpha-induced expression of chemokin

37 genome integrity and cell survival, yet how basal levels and activity of CHK1 are maintained under p

38 d amino acid metabolism when glucagon was at basal levels and at high physiological levels.

39 in contrast, represses BCL6 expression below basal levels and decreases the association of RNA polyme

40 process in H. volcanii that operates at low basal levels and is induced by DNA breaks.

41 mplified these IL-17 responses and increased basal levels and TRAF3IP2 silencing-dependent up-regulat

42 Inhibition of Notch signaling suppresses basal-level and Pygo2-deficiency-induced luminal/alveola

43 were not significantly increased above their basal levels, and diaphragmatic weakness and further inc

44 MCL showed large interpatient variability in basal levels, and elevated levels for the phosphorylated

45 ly reduced brain KYNA to as little as 28% of basal levels, and prevented amphetamine- and ketamine-in

46 At basal levels, Arl8b was primarily found in a perinuclear

47 s were increased at 1 wk and returned to the basal level at 4 wk in nonirradiated proximal femur.

48 rease during a malaria episode and return to basal levels at the end of the transmission season (p<0.

49 Even at low basal levels, ATF3 converges with CSL in global chromati

50 t known if the autophagic process differs at basal levels between CML patients and healthy individual

51 At basal level, Bhmt(-/-) GWAT had the same [(14)C]glucose

52 Vascular permeability was normal at the basal level but elevated in response to high doses of ex

53 ynthase are transcriptionally regulated at a basal level by the specificity protein/Kruppel-like tran

54 ed the return of stimulated CFTR activity to basal levels by >3-fold.

55 transition through the S phase, returning to basal levels by 168 hours, when organ regeneration is co

56 pairs Na(+) uptake, but JI-34 restores it to basal levels by means of increasing cAMP levels.

57 At midbrain and hindbrain basal levels, CB-ir and CR-ir cell bodies were mainly di

58 cells at high levels that are distinct from basal-level co-expression during lineage priming.

59 he scanning session when compared with their basal levels collected over 7 consecutive days, suggesti

60 oncentration dependence of its activity, its basal level concentrations, and how levels fluctuate in

61 ent to mediate perinuclear positioning under basal level conditions of expression, both in integrated

62 -MHC ligands further elevated open-CD3 above basal levels, consistent with a model wherein antigenic

63 quent fall of adrenocorticotropic hormone to basal levels, cortisol remains elevated and coordinated

64 ce and time and found that its amplitude and basal levels display oscillations throughout early embry

65 potent stem cells and gradually decreases to basal levels during differentiation.

66 unoblotting revealed that IRF2 regulated the basal level expression of FAM111A, suggesting that the e

67 uce peritoneal Mvarphi apoptosis or modulate basal-level expression of proinflammatory genes.

68 The pbl13-2 knockout also exhibits elevated basal-level expression of the PATHOGENESIS-RELATED GENE1

69 cterized by divergent promoter sequences and basal-level expression strengths.

70 In contrast, CsA but not MCV1-activated basal level extracellular signal-regulated kinases activ

71 ct was the result of the decline of Arc mRNA basal levels following inhibition of ERK/MAPK by hypothe

72 d for continuous in vivo insulin delivery at basal level for prolonged period after a single subcutan

73 the rate of cardiomyocyte division above the basal level for up to 4 wk after the injury.

74 CLL tumors had elevated basal levels for the phosphorylated forms of BCR-signali

75 induced open-CD3, accounting for half of the basal level found in thymocytes from MHC(+) mice.

76 son, the double positive cells remained at a basal level in mice with early stage MCF-7 tumors, and j

77 esidue (Thr(11)) in Cds1 by Rad3 occurs at a basal level in the absence of three other parallel Rad3-

78 g in transient [Ca(2+)] rises that return to basal levels in 30-60s.

79 RBM3 is expressed at low basal levels in human fetal prostate or in CD133(+) pros

80 ed by CSD, and the production was reduced to basal levels in mice lacking microglia.

81 esponse and is ubiquitously expressed at low basal levels in normal tissues due to Keap1-dependent ub

82 GLP-2 circulates at low basal levels in the fasting period, and plasma levels ri

83 essential macroelements and trace metals at basal levels in two biological models, cells of Chlamydo

84 t Est3p stimulates telomerase activity above basal levels in vitro in a manner dependent on the Est2p

85 lysosomal compartment and exhibited reduced basal levels in WASHout MEFs.

86 sis reveals progressive DNA demethylation to basal levels in week 5-7 in vivo hPGCs.

87 Similarly, light did not increase SNI, above basal levels, in retinas of transgenic mice lacking neur

88 In addition to suppression of basal levels, interestingly, the post-gonadectomy-induce

89 on in both genotypes, but that return to the basal level is delayed in Nf1(-/-) chondrocytes.

90 in SMA iPSCs increased ROS production above basal levels, levels of ROS remained lower than in contr

91 at pathogen infections are important for the basal level of activation and the function of the immune

92 ordered CTA1 to a folded conformation with a basal level of activity that could be further stimulated

93 We disclose a basal level of adult neurogenic activity characterized b

94 cartilage explants in culture increased the basal level of aggrecan degradation, as well as ADAMTS-5

95 ad, p25alpha caused a 4-fold increase in the basal level of alpha-synuclein secreted into the medium.

96 opulations, which could be influenced by the basal level of anandamide.

97 ed expression of Bcl-2 together with a lower basal level of apoptosis.

98 While myeloma cells require a basal level of autophagy for survival, caspase-10 temper

99 Organisms maintain a basal level of autophagy under favorable conditions and

100 cetylglucosamine (GlcNAc), suggesting that a basal level of cAMP is sufficient for stimulation.

101 vity, likely induced by a significantly high basal level of cAMP, which we detected in these cells.

102 omyelocytic leukemia (PML) protein increased basal level of cccDNA transcription activity and partial

103 tumor formation have a preexisting, elevated basal level of chromosome missegregation that is exacerb

104 und of viral RNA translation by sustaining a basal level of CVB3 IRES activity.

105 l mutants, suggesting that FANCD2 provides a basal level of DNA protection countering endogenous lesi

106 d yellow fluorescent protein, demonstrated a basal level of fluorescence resonance energy transfer, w

107 ex vivo than resting macrophages with only a basal level of FR expression.

108 A basal level of frameshifting occurring in the absence of

109 This basal level of H2O2 acts as messenger for transcriptiona

110 PFA tumors exhibit a low basal level of H3K27me3, and, paradoxically, inhibition

111 n of the beta-catenin/TCF-4 axis impacts the basal level of HIV transcription in astrocytes, which ma

112 In addition to this basal level of immunotolerance to NK cells, the prostate

113 R526H is associated with a reduction in the basal level of INa and a failure of PKA stimulation to a

114 We found that the basal level of LC3-II was elevated in both CLN5 disease

115 ated that XBP1 deficiency in ECs reduced the basal level of LC3beta expression and ablated response t

116 ice peaked on day 19, before decreasing to a basal level of light, which remained measurable for the

117 gh affinity, yet some maintain an additional basal level of low affinity, broad reactivity to diverse

118 A basal level of macroautophagy occurs constitutively, but

119 and CD11b(hi) RDC, which express the highest basal level of major histocompatibility complex (MHC) cl

120 le that juxtaposes two bilayers and drives a basal level of membrane fusion.

121 A high basal level of micronuclei as a predictive biomarker for

122 stant BRAF-mutated melanoma cells with a low basal level of mitochondrial biogenesis depend on this p

123 knock-out of TSC2 led to an elevation in the basal level of mTOR signaling.

124 Here, we show that the basal level of NO in breast cells plummets during cancer

125 We recently reported that the basal level of NO in the normal breast epithelia plays c

126 For a subset of truncated AR variants, this basal level of nuclear import can be augmented by unique

127 diverse truncated AR variant species have a basal level of nuclear localization sufficient for ligan

128 Thus, a basal level of open-CD3 is succeeded by a higher, induce

129 oduction is increased and did not affect the basal level of other cytokines.

130 In alpha1(+/-) myocytes, the basal level of phospho-BAD is higher compared with WT my

131 GluN2B subunit levels, as well as the basal level of phosphorylation of GluA1, were reduced in

132 In platelets, the basal level of PI3P was only slightly affected by Vps34

133 tant role for hepatocytes in determining the basal level of plasma tPA and identify regulatory factor

134 mine-induced saliva contained constitutively basal level of protein.

135 f mural cells to stabilize endothelium and a basal level of relevant growth factors.

136 We hypothesized that the basal level of replication stress defines the FACT depen

137 not other Rim acetyltransferases, provides a basal level of resistance to McC and various toxic nonhy

138 The basal level of RIN4 Thr-166 phosphorylation decreased in

139 Here, we show that a basal level of Ser15 phosphorylation occurs in both unst

140 Hnrnph1 mutants showed a marked increase in basal level of synaptosomal hnRNP H and mitochondrial pr

141 significantly altered phenotypes raised the basal level of system output only in unstressed cells an

142 rolysis but does depend on ATP binding and a basal level of UPF1 ATPase activity.

143 rmone analysis revealed significantly higher basal levels of 12-oxo-phytodienoic acid, a precursor in

144 f CaMKII increased striatal DGL activity and basal levels of 2-AG, and CaMKII inhibition augmented sh

145 e treatment, the knockin cell lines had high basal levels of 5-methyl-THF and did not respond to homo

146 However, dwarf fibroblasts express lower basal levels of a number of putative XBP1 target genes i

147 Mean basal levels of Abeta species from three CSF pools were

148 Conversely, basal levels of abscisic acid and aphid feeding-induced

149 at T cells from CCI patients featured higher basal levels of activation and stronger expression of th

150 Stable knockdown of PTK6 reduced basal levels of active STAT3, as well as activation of S

151 nking at distances greater than 20 A yielded basal levels of activity.

152 Fra-1(Delta/Delta) cells had elevated basal levels of antioxidant enzymes and intracellular gl

153 strains of mice are known to differ in their basal levels of anxiety and behavioral response to drugs

154 on at serines 1181 and 1201 in mouse reduces basal levels of anxiety/depression-like behaviors.

155 Although basal levels of Arf mRNA were increased by C/ebpbeta los

156 is unknown whether exercise training alters basal levels of autophagy and whether autophagy is requi

157 ZV induces levels of autophagy far above the basal levels of autophagy in human skin, a major site of

158 vitamin D supplementation in mice increases basal levels of autophagy in the normal mammary gland, h

159 Finally, basal levels of autophagy were markedly reduced in C9ALS

160 ell lines of multiple genotypes exhibit high basal levels of autophagy.

161 a high methionine diet containing sufficient basal levels of B vitamins.

162 They also suggest that the basal levels of BCL-xL should be predictive of tumor res

163 These results suggest that basal levels of BDNF transmission in the NAc core exert

164 n 1 and LC3 and was required for maintaining basal levels of Beclin 1.

165 However, basal levels of Ca(2+) are permissively required.

166 during the odorant response and examined how basal levels of cAMP are controlled.

167 l inducers must stimulate cAMP, or if normal basal levels of cAMP are required to maintain cellular h

168 the nonreplicative phase in response to the basal levels of cellular amino acids that are not suffic

169 6-BL6 mouse melanoma cell line expresses low basal levels of Cx26 and Cx43, rendering them gap juncti

170 itatory synaptic strength in PFC determining basal levels of depression-like behavior.

171 avior; while the sexual activity reduces the basal levels of depressive behavior in male mice, it red

172 However, basal levels of DMPK protein are reduced by half in DM1

173 h even one mutant copy of RB1 have increased basal levels of DNA damage and increased mitotic errors.

174 cavenger N-acetyl cysteine (NAC) reduced the basal levels of DSB, eliminated un-repairable ROS-induce

175 Normalizing basal levels of each measurement to equal those of femal

176 ent studies on PTTH signaling indicated that basal levels of ecdysteroid negatively affect systemic g

177 , ESMV exposure induced up-regulation of the basal levels of endogenous human Oct4 mRNA in Muller cel

178 Recent hypotheses posit that basal levels of endogenous NO increase lymphatic contrac

179 ife of ERBB2, explaining the increase in the basal levels of ERBB2, p-ERBB2(Y1248), and p-AKT(S473).

180 megakaryocyte antigen expression, as well as basal levels of ERK1/2 phosphorylation.

181 Basal levels of ERV and viral defense gene expression si

182 l mRNA transcripts, even from cells with low basal levels of exosome secretion.

183 induced cellular injury and restored SMPDL3b basal levels of expression.

184 e response to cocaine secondary to increased basal levels of extracellular dopamine in the nucleus ac

185 t FLX, FLX4, FES1, and SUF4 are required for basal levels of FLC expression in the absence of FRI.

186 achexia and sepsis, and further suggest that basal levels of FoxO play an important role during norma

187 oGAD67) and constitutively active to produce basal levels of GABA, the membrane-associated GAD65 exis

188 anscripts and found that several had reduced basal levels of gene expression but were similarly regul

189 ce of d-serine, together with the release of basal levels of glutamate, contributes to synaptic damag

190 Consistent with these findings, higher basal levels of GSK3 activity in a panel of human lung c

191 We showed that variation in basal levels of heme oxygenase 1 (HMOX1) contribute to t

192 munized SCD CD16+ monocytes expressed higher basal levels of heme oxygenase-1.

193 Although Pbs2(DD) cells did not exhibit high basal levels of Hog1 phosphorylation, overexpression of

194 s exhibit spontaneous bursting and have high basal levels of hormone secretion, while gonadotrophs ex

195 the hp53-mediated response by ensuring that basal levels of hp53 are available to precondition the c

196 1 to avoid cytotoxicity in normal cells with basal levels of ICAM-1 expression.

197 In this article, we show that basal levels of IFN regulatory factor (IRF) 5 in pDCs we

198 (rs1333049) in 9p21 was associated with: 1) basal levels of IFN-I in plasma from 148 healthy male su

199 ibroblasts from PAR2ko mice expressed higher basal levels of IFNbeta than wt mice did.

200 ed in a resynthesis of IkappaB, in which the basal levels of IkappaB were restored only but did not r

201 pendent regulatory elements and maintain low basal levels of inducible genes.

202 Neuronal DCAP-1 affects basal levels of INS-7, an ageing-related insulin-like pe

203 or, dipeptidyl peptidase 4 (DPP4) and higher basal levels of interferon in these cells.

204 Basal levels of jasmonic acid were substantially higher

205 Basal levels of JNK were significantly higher at P4 than

206 zygotes were viable and exhibited comparable basal levels of KCC2 expression and activity relative to

207 cancer cell line (769-P) that expresses high basal levels of KIM-1.

208 ed in the mechanosensory neurons to maintain basal levels of locomotion.

209 In GnRH-CREB KO mice, basal levels of luteinizing hormone (LH) and the postova

210 y tumor cell paracrine factors, induces high basal levels of macrophage IL-6 in a TAM model system [t

211 Further, basal levels of many components of the DDR were expresse

212 Thus, lactate raises basal levels of MAPK and Etv5b (a critical effector of t

213 Basal levels of metabolism vary significantly among indi

214 Although cells tolerate basal levels of modification, exceeding them induces apo

215 ce display normal to only moderately reduced basal levels of most circulating Ig subclasses and gut-a

216 e show that nonactivated macrophages express basal levels of mTNF-alpha and respond to anti-TNF-alpha

217 primary thymocytes expressed low to moderate basal levels of Nck-accessible PRS ("open-CD3"), althoug

218 While basal levels of NO in cortical slices depended on both a

219 l as in Ifnar1(-/-) BMM, both expressing low basal levels of Oas genes.

220 t myeloid cells express significantly higher basal levels of OAS transcripts than nonmyeloid cells.

221 ion of PERK as the major kinase to determine basal levels of p-eIF2alpha in primary neuronal cultures

222 Basal levels of p75(NTR) in neurons are maintained in pa

223 rats exhibited significant increases in the basal levels of phospho-tuberin and fibronectin expressi

224 Basal levels of phosphorylated ERK1/2 are also elevated

225 The basal levels of phosphorylated mTOR and protein kinase B

226 We developed an assay to measure basal levels of phosphorylated signaling intermediates b

227 that PKCdelta-S359A overexpression increases basal levels of phosphorylation on substrates with both

228 While insulin blocked basal levels of PINK-1-mediated mitophagy in bronchial e

229 earranged ALL samples, we observed increased basal levels of pJAK2, pSTAT5, and pS6.

230 However, Japanese medaka had different basal levels of plasma E2, plasma VTG, and fecundity.

231 me, we demonstrate that dASCs produce higher basal levels of proNGF and mature NGF compared to SCs.

232 attention has been paid to how IRFs maintain basal levels of protection against viruses.

233 he PspA-TatA interaction, demonstrating that basal levels of PspA already interact with TatA.

234 Loss of Nrf2 resulted in elevated basal levels of reactive oxygen species but did not affe

235 eased mitochondrial respiration and elevated basal levels of reactive oxygen species that cause activ

236 nhibitors had no effect on Ca(2+) release or basal levels of retrograde actin flow; however, they com

237 Basal levels of ROS and sensitivity to H(2)O(2) were com

238 Basal levels of ROS and stimulated levels of ROS were bo

239 We found higher basal levels of S845 phospho-GluA1 (P-GluA1) and cell su

240 Basal levels of serum IgM and IgG were significantly red

241 and aging (18-24 mo) mice revealed elevated basal levels of several products [1-palmitoyl-2-(5-oxova

242 at serine 211 is required to maintain normal basal levels of Sox9 as well as mediate increased Sox9 l

243 SMPDL3b-overexpressing podocytes had higher basal levels of sphingosine-1-phosphate and maintained b

244 Normal basal levels of testosterone in serum and LCs were obser

245 The p8 subunit of TFIIH maintains the basal levels of the complex by interacting with the p52

246 ac1-p65 signaling cascade not only maintains basal levels of the immune defense modulating IFNs and C

247 P-13 in osteoblastic cells without affecting basal levels of the mRNA.

248 Analyses were made of basal levels of the pro-apoptotic c-jun N-terminal kinas

249 To promote basal levels of the process in pathological settings, we

250 onses to BCR stimulation along with elevated basal levels of the proximal BCR signaling components B

251 gen while avoiding normal tissues expressing basal levels of the same antigen.

252 d lung fibrosis, whereas it had no effect on basal levels of these proteins.

253 iquitination of Nox4 and for maintaining low basal levels of this reactive oxygen species-generating

254 protein array data for tumors revealed that basal levels of Thr-7-phosphorylated Hsp90alpha were cor

255 ts reveal broad between-group differences in basal levels of trimethylated histone protein H3 at lysi

256 obtained by striatal microdialysis in vivo, basal levels of tryptophan, kynurenine, and QUIN were 41

257 A(-/-) mouse express reduced TLR7 but normal basal levels of type I IFN.

258 oss of LRRK2 in macrophages induces elevated basal levels of type I interferon (IFN) and interferon s

259 Basal levels of type I interferon in the long-term infec

260 ivation of mTOR-dependent protein synthesis, basal levels of ULK1 are promptly restored, but the acti

261 euron degeneration, findings suggesting that basal levels of urate in mice do not appreciably protect

262 s, SK1 overexpression slightly increased the basal levels of VEGF, but did not block the inhibitory e

263 s lacking HPL-2 is associated with increased basal levels of XBP-1 activation and ER chaperone expres

264 In the absence of Sec63, basal levels of Xbp1s activity in collecting ducts is bo

265 During exponential phase growth, basal levels of xdhABC expression may be achieved by GTP

266 very high levels of cortisol in the face of "basal" levels of adrenocorticotropic hormone.

267 hat, in synaptically active neurons, modest "basal" levels of postsynaptic Ca(2+) physiologically sup

268 ly downregulated C3 promoter activity at the basal level or in the presence of interleukin-1beta (IL-

269 topped the intracellular calcium returned to basal levels or below.

270 e and blood urea nitrogen when compared with basal levels (P = 0.01 and P = 0.03).

271 ood urea nitrogen values comparable to their basal levels (P = 0.49 and P = 0.59), whereas animals tr

272 t-K089 3 times daily restored tear volume to basal levels, preventing corneal epithelial disruption w

273 At basal levels, stress-granule formation appears normal in

274 oli that enhances mutation 322,000-fold over basal levels, surpassing the mutational efficiency and s

275 ding that strains with both higher and lower basal levels tend to enrich their proteomes with antioxi

276 GF4 deprivation of TSCs reduces geminin to a basal level that is required for maintaining endocycles

277 rroring and shared neural representations at basal levels, that develops into more advanced cognitive

278 plasmids did not improve production over the basal level, their identification enables future enginee

279 cells rise in frequency, only to decline to basal levels thereafter.

280 It is now believed, however, that at basal levels these molecules also have a beneficial cell

281 significant change in blood pressure at the basal level, they were more sensitive to low-dose angiot

282 he surface display of endogenous ZnT8 from a basal level to 32.5% of the housekeeping Na(+)/K(+) ATPa

283 However, a key issue is the requirement of a basal level transcript from the target loci to initiate

284 aining protein counteracts H3K9me to promote basal level transcription of endogenous silenced loci in

285 at JMJ24 plays a conserved role in promoting basal level transcription of endogenous silenced loci to

286 is soluble and properly folded and activates basal-level transcription of its target vqmR in the abse

287 p53 is a short-lived protein with low basal levels under normal homeostasis conditions.

288 g the cancer glioblastoma multiforme, at the basal level, under EGF stimulation, and under erlotinib

289 d after 21 d withdrawal, and returned to the basal level upon cocaine re-exposure after 21 d withdraw

290 poration, all of which were restored to near basal levels upon discontinuation of dox.

291 bsided, unlike as in the wild type , to near-basal levels upon prolonged stress treatment due to down

292 es 1 and 2 (ERK1/2) to approximately 3-times basal levels via a receptor-independent mechanism when S

293 n content was blocked by blebbistatin, while basal levels were reduced by nocodazole, indicating that

294 horylation and node localization returned to basal levels when cells adapted to osmotic conditions an

295 ase activity in control livers compared with basal levels, whereas liver IL-10 expression decreased 1

296 ocorticotropic hormone levels return to near basal levels while cortisol levels remain raised as a re

297 ase in enzyme activity, which was reduced to basal levels with phosphatase treatment.

298 d Lig activities increased fivefold over the basal level within minutes of DNA methylation damage; th

299 evels remained significantly higher than its basal level within the first 24 hours after ischemia ons

300 ulated by PhoB/R, although it can occur at a basal level without a requirement for any regulatory ind