ライフサイエンスコーパス: base

1 sors (e.g. enzymatic, immunosensors, and DNA-based).

2 sufficient for its targeting to the ciliary base.

3 tate residue that probably acts as a general base.

4 bset of 77 906 participants with up to 5 web-based 24-hour-recall food frequency questionnaires (2009

5 development of biomaterials suited for light-based 3D printing modalities with an emphasis on bioprin

6 ice of either sex either by diphtheria toxin-based ablation of >50% of mature DG granule cells (GCs)

7 tion of both reaction partners, chiral Lewis-base activation of the electrophile and light activation

8 replace traditional lecturing with evidence-based, active-learning course designs across the STEM di

9 length gB protein with an MF59-like squalene-based adjuvant, the gB ectodomain protein (lacking AD-3)

10 We also examined hospital-based affiliation.

11 recent achievements in the accuracy of image-based AI for skin cancer diagnosis to address the effect

12 tant complementary role to phylogenetic tree-based analysis, such as is done in the Nextstrain projec

13 ere detected in the circulation by both mRNA-based and genomic DNA-based sequencing.

14 ice, 11.9% in rural location, 26.8% hospital-based, and 24.6% in primary care).

15 In this work, two new curvature-based angularity indices are introduced and compared to

16 uracy, we performed a large number of expert-based annotations, 72,722 in total.

17 diment for the design of sustainable peptide-based antibiotics that can be hydrolyzed by wastewater p

18 the applicability of an untargeted, activity-based approach for SCRA detection in OF.

19 Using a trait-based approach that incorporated genomic and phenotypic

20 Here, we apply a high-resolution, pressure-based approach to describe how two fishes, bluegill sunf

21 l hundred clinical trials have tested immune-based approaches in childhood cancers, few have been gui

22 When given to all men and women, DTG-based ART could reduce the level of NNRTI PDR from 52.4%

23 that, compared to the continuation of NNRTI-based ART, introducing DTG would lead to a reduction in

24 eased viral suppression compared with clinic-based ART, particularly among men, eliminating dispariti

25 Herein, we rationally design a DNA-based artificial molecular signaling system that uses th

26 le enzyme-linked immunosorbent assay (ELISA)-based assay that uses the temperature-dependent loss of

27 f MTCH2 using luminescence- and fluorescence-based assays, and by analyzing ribosome-profiling and ma

28 The use of test set-based assessment schemes in a breast screening program h

29 and the results of the gold-standard culture-based AST measured over days.

30 ased cardiovascular risk receiving metformin-based background therapy, specific GLP-1 RAs and SGLT-2

31 mily of 3-19 nM-affinity, alpha/beta-peptide-based binders to 14-3-3.

32 y slowly progressive, and objective, imaging-based biomarkers are critically needed.

33 try, for the fabrication of a Bio-Nano-PEDOT-based biosensor for lactate detection which had a respon

34 Field-based brain imaging research, including populations unde

35 o a hairpin structure that is cleaved at its base by an enzyme complex known as the Microprocessor (D

36 Rate-based calculations in packing column demonstrated a kine

37 Several tools, from base-calling to genome assembly, were ported and benchma

38 Cytosine DNA bases can be methylated by DNA methyltransferases and su

39 eat potential to improve the efficacy of DSF-based cancer therapy.

40 The EHR-based case-control studies identified that the prescript

41 including metal organic framework design, TM-based catalyst design, the trafficking of TM ions in bio

42 Two relevant CB7 effects are proposed, a base-catalyst mediated by the CB7 portal and an inhibito

43 tem was validated with the study of vanadium-based catalysts during propane oxydehydrogenation (ODH).

44 In many cases, these peptide-based catalysts have enabled novel multifunctional subst

45 safe and improved alternative to gadolinium-based chelates.

46 promising approach for constructing reaction-based chemosensors using porphyrinoid dimers of nonplana

47 s were treated with gemcitabine and S-1 (GS)-based chemotherapies with/without radiation.

48 enabled glaucoma dashboard." We used density-based clustering and the VF decomposition method called

49 We conducted a multicountry population-based cohort study of all recorded singleton live births

50 Acid-base conditions modify artery tone and tissue perfusion

51 llege of Radiology as a group III gadolinium-based contrast agent (GBCA), which indicates that there

52 aging after interstitial pedal of gadolinium-based contrast medium under local anesthesia.

53 , used routinely acquired data for a records-based controlled before-and-after study, and collected q

54 tance of discrete traits and the genetically based correlation between relatives for quantitative tra

55 st response assessment with both PET- and CT-based criteria.

56 Fiber-optics-based cuvetteless micro-spectrophotometry has been used

57 Here, we use population-based data from ~22,000 persons of known HIV status to c

58 be used for the growth of other noble-metal-based delafossites, which are known to be challenging du

59 ttings in South Africa and Uganda, community-based delivery of ART significantly increased viral supp

60 The efficient ligand-based design approach adopted demonstrates its versatili

61 which directly provides the direct molecular-based design of functionalized polymer/carbon spheres.

62 anagement can maintain the fidelity of video-based diagnostics in the face of missing values and vari

63 research teams and their application in PCR-based diagnostics, high-affinity DNA aptamer generation,

64 We applied nanopore-based direct RNA sequencing to characterize the developm

65 vironmental conditions and emerging pathogen-based diseases.

66 Using paired collision- and electron-based dissociation spectra, O-Pair Search identifies O-g

67 , suggesting that PPR65 cannot bind modified bases due to differences in the structure of the active

68 analogs along with the natural A, T, G and C bases during DNA synthesis, which allows for labeling of

69 toolkit and illustrates a novel strategy for base editor optimization.

70 n overview of the literature on carbon black-based electrochemical (bio)sensors, highlighting current

71 ial focus on the fabrication of carbon black-based electrodes in the realisation of sensors and biose

72 has attracted attention for realizing carbon-based electronic devices.

73 First, NZ's production- and consumption-based emissions were quantified using multiregional inpu

74 (P = 0.003), and greater computed tomography-based emphysema (P = 0.02) compared with 1,411 white ind

75 ollowed by linkage disequilibrium (LD) score-based enrichment testing for each trait.

76 Bead-based epitope assay (BBEA) was used to quantitate the le

77 Although APE2 plays essential roles in base excision repair and ATR-Chk1 DNA damage response (D

78 We performed behavioral and brain-based experiments, with the latter employing electroence

79 article properties and compared them to mass-based exposures.

80 ed 10 studies of the use of autologous serum-based eye drops for severe dry eye disease and 4 studies

81 Our study reveals that ad hoc or experience-based flow management is no longer tenable to maintain t

82 Using ROI-based fMRI analysis, we measured fMRI activity for valid

83 Integrin-based focal adhesion complexes link the glial membrane t

84 Molecular dynamics based folding simulations that rely on knowledge of the

85 To inform the development of insect-based foods, we analysed selected minerals (Fe-Mn-Zn-Cu-

86 is needed, as well as providing an evidence base for efficiently distributing limited healthcare and

87 Utilizing an evidence-based framework, 3 gene curation teams blinded to each o

88 density maps which was tested by the Phenix based fully automatic method.

89 gates and a comprehensive set of ganglioside-based glycoconjugates.

90 Evidence-based guideline development for surgical and dental pres

91 nexpected based on efficacy data or evidence-based guidelines.

92 alidated internal mRNA m7G sites, a sequence-based high-accuracy predictor, the first web server for

93 analysis and development of improved mixture-based, high-throughput drug discovery techniques.

94 In this article, we utilized a smartphone-based image acquisition method for capturing RBC images

95 Unlike the traditional antibody-based immunoassays, our approach is capable of monitorin

96 rapy and has general implications for T cell-based immunotherapies.

97 iently inhibiting LDH during adoptive T cell-based immunotherapy, with an unanticipated cooperative a

98 Moreover, it relies on the local/window-based information while lacking to consider useful prote

99 The key challenge in generating antibody-based inhibitors is the lack of fundamental information

100 A water droplet surface tension (WDST) based innovative method was developed that can quantify

101 Using data from a large, community-based integrated health care setting, we examined the ri

102 group was moderate for multicomponent clinic-based interventions but was low or very low for other in

103 Evidence-based interventions can deliver substantial public healt

104 and has significant implications for network-based interventions.

105 y kinetic simulations of laser driven sheath-based ion acceleration with a kilotesla-level applied ma

106 d iterative reconstruction (SBIR), and model-based iterative reconstruction (MBIR) in a retrospective

107 filtered back projection (FBP), statistical-based iterative reconstruction (SBIR), and model-based i

108 re of the sulfonyl moiety, which serves as a base-labile protecting group and confers crystallinity t

109 red to as the testing effect or as retrieval-based learning) and consider directions for future resea

110 of rewarded actions, and the other is model-based learning, which considers the structure of the env

111 h(6) secondary building unit and a tetrazole-based linker.

112 lycosites using graph theory and probability-based localization.

113 Cell surface-based loss-of-function screens reveal that ATP7A, a copp

114 Among these, Sm(2) Co(17) -based magnets are excellent candidates owing to their hi

115 opment of a tantalum oxide nanoparticle (NP)-based mass tag for MC immunoassays.

116 however, shows a dependency on patient size, base material, and iodine content; particularly the latt

117 This filament-based mechanism of enhanced cooperativity demonstrates h

118 Here we identify an adaptive circuit-based mechanism that enables Drosophila to form sleep-de

119 Finally, microscopy-based metabolic analysis revealed that migratory cells s

120 A specific class of deep learning-based methods allows for the prediction of regulatory ef

121 lso opens the door for nanoengineered, solar-based methods to remediate recalcitrant micropollutants

122 f TE insertions that were missed by Illumina-based methods, including a novel micropia-like element t

123 sors with extremely well-established silicon-based microcircuit chips offers a viable route for in-se

124 learning approach, we built gene expression-based models to predict drug sensitivity for 265 common

125 the surface-enhanced Raman scattering (SERS)-based molecular sensors for detection of two putative fa

126 Patients underwent prospective, protocol-based monitoring consisting of repeated coronary angiogr

127 inefficiencies of the U.S. private insurance-based, multipayer system.

128 use for biomedicine, only a few of the gold-based nanodevices are currently tested in clinical trial

129 Thus, our FRET-based nanoparticle biosensor enables detection of nuclei

130 mmittee machines-in the context of memristor-based neural networks.

131 ubles the estimated efficiency of population-based newborn screening to prevent ketoacidosis, and ena

132 However, current CRISPR-Cas-based nucleic acid biosensing has a lack of the quantita

133 nity assembly mechanisms by phylogenetic bin-based null model analysis (iCAMP).

134 A, and five tri-CiQA, were identified on the base of their MS fragmentation profile.

135 d salinity distributions and compare defined bases of fresh water with salinity distributions and gro

136 ent, 13 wine grape varieties and 4 locations based on (1)H NMR spectra.

137 This advanced cellular construct based on a combinatorial nano-engineering and biomateria

138 tons from suitable propargyl vinyl ethers is based on a one-pot, multistep process entailing a gold(I

139 substantiated by a molecular modeling study, based on a receptor-driven docking model and including a

140 est efficiency reported so far for catalysts based on a single metal ion mechanism.

141 cts showed consistent benefits for subgroups based on age, sex, diabetes, treatment with an ARNI and

142 essary for Pro-sigma(K) cleavage by SpoIVFB, based on analysis of mutants that bypass the need for re

143 However, the oxygen sensors based on beta-Ga(2)O(3) and other existing materials lac

144 n more conscious about healthy food products based on bioactive ingredients in order to protect again

145 Here, we use a general model based on biochemical kinetics to quantify the combined e

146 chemicals is especially attractive, as it is based on cheap renewable raw materials and often exhibit

147 further external validation, the CLIV Score based on clinical and immune-virological parameters is p

148 Development of the prediction model was based on clinical information available during ICU stay.

149 ng methods for the classification of 6 types based on colour and residual sugar content, 13 wine grap

150 Approaches based on compacted de Bruijn graphs to identify and exte

151 compare fixed-time to on-the-fly decisions, based on comparing the likelihoods of anterior/posterior

152 It is based on conjugating nanoplastics with functionalized me

153 nary experts in the field, new core criteria based on contemporary cardiovascular imaging parameters

154 The method is based on conversion of carboxylic acids to the correspon

155 The approach is based on convolutional neural networks (CNNs), which may

156 Based on corneal microstructure, we introduce and fully

157 Based on CsMAF1 structural data, we propose a mechanism

158 Warning signs were determined based on daily clinical assessments, laboratory tests an

159 Subsequent differential expression analyses based on datasets integrated from different platforms sh

160 to sub-population and production environment based on differences in physicochemical grain properties

161 Current diagnostic approaches are based on discordant measures, suffer from subjectivity a

162 Many of these associations are unexpected based on efficacy data or evidence-based guidelines.

163 Finally, we discuss future perspectives based on emerging techniques and insights.

164 o estimate population numbers in small areas based on enumeration data from sample areas and nationwi

165 Arylazopyrazole derivatives based on four core structures (4pzMe, 3pzH, 4pzH, and 4p

166 and emergence of drug resistance: inference based on genomic, transcriptomic, epigenomic and/or prot

167 port a time-calibrated phylogenomic analysis based on genotyping-by-sequencing data [6] of the 15 spe

168 Genetically encoded dopamine sensors based on green fluorescent protein (GFP) enable high-res

169 as a catalytically inactive mutant in vivo (based on in vitro peptide studies) actually retains subs

170 Many biological processes are based on interfacial protein action, ranging from cellul

171 the academic sector as new forms of research based on large amounts of data will be possible, and new

172 therapy, then surgery and radiotherapy boost based on margins with continued chemotherapy).

173 One molecule generator, based on match molecular pairs, performed excellently ag

174 control, preservation of serviceable hearing based on median pure tone averages (PTA), and procedure-

175 tical applications in rechargeable batteries based on metal anodes.

176 derstanding is so far limited to the results based on Newtonian and neutral viscoelastic carrier flui

177 tment-by-subgroup interactions for subgroups based on NYHA functional class and race.

178 is only one alternative non-invasive system based on Optical coherence tomography (OCT) technology,

179 Epitaxial heterostructures based on oxide perovskites and III-V, II-VI and transiti

180 e stability of the mayonnaises were analyzed based on parameters including droplet size, viscosity, p

181 mes prepared by US and MF were characterized based on particle size, structure and stability.

182 , chosen empirically to give 95% specificity based on permuting the series.

183 Based on previous studies of murine leukemia virus and H

184 Based on primary and beta-secondary isotope effects, it

185 of novel information and guiding exploration based on prior experience.

186 ssigned into 5 weight loss maintenance diets based on protein and glycemic index content and followed

187 An attract-and-kill trap based on psyllid behavior would fill a niche for monitor

188 sity (over 4.0 mC m(-2)) in a TENG electrode based on quantified surface micro-contact efficiency and

189 Based on recent experimental results for single cells, w

190 omadic movements, particularly for movements based on resource availability alone.

191 piratory syndrome coronavirus 2 (SARS-CoV-2) based on reverse transcriptase polymerase chain reaction

192 Although many ligands were predicted based on sequence signatures, ligands of shorter sequenc

193 When relevant, we provide information based on sex and common classifications of race/ethnicit

194 We evaluated pre-HD stratification models based on single visit resting-state functional MRI (rs-f

195 Based on six alternative land-use plans, we identified t

196 Monetizing the results based on social costs of carbon and other air pollutant

197 0.91) and progression to diabetes (AUC 0.92) based on standard cross-validation (CV).

198 n quaternary assemblies (binders/nonbinders) based on statistical potentials.

199 Based on stratigraphy near the crater, between 7.5 x 10(

200 Based on structural and affinity analyses, we designed t

201 mechanism driving root development is mainly based on studies of the dicot model Arabidopsis.

202 Based on such temperature control strategy, NGD sensitiv

203 were identified with the TWAS FUSION method, based on summary statistics from the largest genome-wide

204 abundances in transgenic Populus trichocarpa based on targeted knockdowns of specific monolignol gene

205 A PRS based on the 10 established PTC SNPs showed a stronger p

206 Based on the 5.2 M SNP dataset, major QTLs were located

207 PIPs we have developed a new cell free assay based on the ability of the receptor to prevent alkaline

208 on and odor processing in all vertebrates is based on the assumption that receptor neuron axons exclu

209 Here we design small peptidic inhibitors based on the atomic structure of the core of alpha-syn f

210 Based on the binding mode of adenosine 5'-(alpha,beta-me

211 ew insights and infection control strategies based on the dynamics of the pathogen lineages derived f

212 enable and accelerate KT in children <=15 kg based on the establishment of one specialized transplant

213 SCVF is estimated to reach about 75,000 t/y based on the existing inventory calculation; however, th

214 cannabinoid type 1 receptor (CB1R) signaling based on the fundamental role of the endocannabinoid sys

215 n cancer is matching patients and treatments based on the genomic characteristics of an individual an

216 rstand the molecular basis of imaging traits based on the interpretation of what the neural network h

217 tative agreement with a theoretical estimate based on the measured imperfections of the experiment.

218 Based on the mechanism, an ultrahigh projected charge de

219 Based on the obtained results, the linearity of the bios

220 Based on the RCSQ results, sleep quality was assessed to

221 of isomers, named open (O-) and closed (C-), based on the ring conformations in the vicinity of the N

222 Can general trends in ECH be formulated based on the type of electrocatalyst?(3)What are the imp

223 T FESTA (SRI-FESTA) experiment is described, based on the use of a modulated spin echo for the initia

224 The process was based on the utilization of magnetic zinc-imidazole fram

225 A synthetic phage display library based on the variable domain of new antigen receptor (VN

226 tional framework for adapting to novel tasks based on their relationship to prior tasks.

227 Splitting protocols based on these findings could improve graft survival aft

228 Based on these results, the predicted inactive conformat

229 Based on this experience, we also provide a roadmap for

230 e of 14 species of medically important mites based on total RNA sequencing data sets generated in thi

231 d resolution, using novel collimator designs based on tungsten.

232 the RAG strand transfer complex that differ based on whether target site DNA is annealed or dynamic.

233 .IMPORTANCE Vesicular stomatitis virus (VSV)-based oncolytic viruses are promising agents against pan

234 ting individuals in non-help-seeking samples based only on more severe symptom cutoff thresholds will

235 through both homogeneous and non-homogeneous base-pair sequences.

236 categories of features of the first VF: (1) base parameters (age, mean deviation, pattern standard d

237 pe.Objectives: To determine whether such Crs-based phenotypes existed among patients with ARDS before

238 of 3 new adipose IR genes by overexpression-based phenotypic rescue in the Simpson-Golabi-Behmel syn

239 phogenesis of the rhabdomere, the microvilli-based photosensitive organelle of Drosophila photorecept

240 In summary, our yeast-display-based platform yields high-quality MHC-II-binding peptid

241 ional barrier, we have created a dynamic web-based platform, NASQAR (Nucleic Acid SeQuence Analysis R

242 me Atlas (TCGA), with both RNA-Seq and array-based platforms available.

243 cability of our approach to facilitate image-based pooled CRISPR screens.

244 d to the improved downstream gene expression-based prediction of disease outcome.

245 ve found widespread applications as activity-based probes and as irreversibly binding drugs.

246 surgery ranged from 66% to 95.6% for office-based procedures versus 50% to 97.7% for facility-based

247 procedures versus 50% to 97.7% for facility-based procedures.

248 Detection of animal materials in gelatin-based products is required to address religious and cult

249 o mitigate acrylamide concentration in wheat-based products.

250 We propose a general acid base-promoted catalytic mechanism, invoking direct nucle

251 Wines fined with egg albumin and plant-based proteins from potato, pea, and grape seed as recen

252 oposed, to achieve harmonization of registry-based quality outcome measures for TEVAR.

253 three-dimensional cartridge and a smartphone-based reader.

254 pecific DNA sequences using a combination of base readout and shape recognition, some fundamental asp

255 arios if ART initiators are started on a DTG-based regimen, and those on NNRTI-based regimens are rap

256 d on a DTG-based regimen, and those on NNRTI-based regimens are rapidly switched to DTG.

257 switch to WHO-recommended dolutegravir (DTG)-based regimens could reduce this threat due to DTG's hig

258 rary of nearly all possible variants in a 36 base region of SCN5A in the S4 voltage sensor of domain

259 ibe an ultrasensitive form of polymerization-based regulation employed by human CTP synthase 2 (CTPS2

260 I), the United States' first regional market-based regulatory program designed to reduce greenhouse g

261 he existence of an underlying adaptive codon-based regulatory response inherent to the genetic code.

262 This population-based retrospective cohort study assessed whether a vali

263 ospray ionization mass spectrometry (ESI-MS)-based sample injection at a sampling rate faster than cu

264 Climate simulation-based scenarios are routinely used to characterize a ran

265 ility, and stability of three series of urea-based sEH inhibitors.

266 The paper-based sensor was then engineered with a novel and highly

267 rculation by both mRNA-based and genomic DNA-based sequencing.

268 dated objective and individual-level housing-based SES index (HOUSES) would serve as a predictive too

269 Computationally efficient all-atom structure-based simulations, calibrated against explicit solvent s

270 Here, we use a machine-vision-based single-particle analysis (SPA) method to successfu

271 acid coated magnetic nanoparticle (SAC-MNPs) based sonication assisted dispersive solid phase extract

272 and performed voxelwise analysis with tract-based spatial statistics.

273 IN, a web server that couples a graph mining-based strategy to detect motifs at the protein-ligand in

274 erstanding of ion transport behavior in wood-based structures enhances the capability to design high-

275 However, few community-based studies have been published and the true PeV infec

276 In a population-based study in Iceland, children under 10 years of age a

277 the effects of varied representations of AI-based support across different levels of clinical expert

278 ransport capabilities using metalloporphyrin-based supramolecular arrays.

279 perforation in the context of the population-based Surveillance of Enteric Fever in Asia Project (SEA

280 an independent, confidential, voluntary, web-based survey sent electronically to 1643 United States h

281 Here, we developed a CRISPR-based system for simultaneous quantification of mRNA and

282 forms any previously reported values for MOF-based systems.

283 e results provide novel behavioral and brain-based targets for treatment of pediatric anxiety disorde

284 Bevacizumab was chosen as the antibody-based therapeutic.

285 ovide insights into the future of microbiota-based therapeutics for CDI.

286 g opportunities for the future of macrophage-based therapies in oncology are included.

287 's) and 20 age-matched controls, using a HOA-based through-focus analysis performed on the logNS IQ m

288 ated ecosystem services modeled with the web-based tool AguAAndes.

289 [605/713], P < 0.001), and for those on EFV-based treatment (60% [12/20] vs 86% [214/248], P = 0.002

290 % [214/248], P = 0.002) and for those on DTG-based treatment (61/92 [66%] vs 84% [391/465] P < 0.001,

291 We developed a gradient-based unsupervised clustering method to extract the patt

292 , our ability to link genes to phenotypes is based upon a handful of model microorganisms.

293 Instead we recommend a topographic approach based upon OCT probability maps and a 10-2 VF.

294 en inferred to display a narrow distribution based upon the characterized synthases, DncV and Hypr GG

295 aled that MPS populations could be separated based upon tissue of origin.

296 vaccine 4CMenB is a new, recombinant protein-based vaccine that is licensed to protect against invasi

297 ggregate patients within RCTs to define risk-based variation in benefit, and an "effect-modeling" app

298 The release of PHI-base version 4.8 (September 2019) contains 3454 manually

299 years of a multicentre European birth cohort based was undertaken using an online parental questionna

300 urated sphingomyelins (even if having an SFA base) were not associated with risk of diabetes.