ライフサイエンスコーパス: base analog

1 crease in the fluorescence intensity of this base analog.

2 2-Aminopurine (AP) is a highly mutagenic base analog.

3 ONs that are also substituted with the same base analogs.

4 annaschii that shows a preference for purine base analogs.

5 rs by misincorporating natural DNA bases and base analogs.

6 f the hydrogen-bonding properties of the two base analogs.

7 d compared with (18)F-AzaFol, the folic acid-based analog.

8 position of harmine to synthesize 29 harmine-based analogs.

9 gths compared to their 1st-generation phenyl-based analogs.

10 By inserting the base analog 2-aminopurine (2-AP) at designated positions

11 dam mutant strains are sensitive to the DNA base analog 2-aminopurine (2-AP), we screened for 2-AP-r

12 The base analog 2-aminopurine (AP) strongly promotes A.T to

13 zed DNA templates containing the fluorescent base analog 2-aminopurine in place of adenine at specifi

14 x formation, DNA internally labeled with the base analog 2-aminopurine in place of adenine to monitor

15 d undamaged duplexes carried fluorescent DNA base analogs 2-aminopurine and 1,3-diaza-2-oxophenoxazin

16 serted into probe oligonucleotides using the base analog 3-nitropyrrole.

17 as an abasic site, a thymidine dimer or the base analog 5-nitroindol and performed PCR amplification

18 f local DNA conformations, using the guanine base analog 6-methyl isoxanthopterin (6-MI) as a structu

19 Their DNA contains the base analog 6-thioguanine (6-TG), which acts as a UVA ph

20 were selectively killed upon exposure to the base analogs 6-azauracil and 8-azahypoxanthine for 48 hr

21 The dNTPs of two other base analogs, 7-nitro-7-deazahypoxanthine (NitrocH) and

22 osyltransferase to confer sensitivity to the base analog 8-azahypoxanthine.

23 ing synthetic consensus promoters containing base analog and other substitutions at -11 in the non-te

24 own to be capable of reducing N-hydroxylated base analogs and nucleoside analogs to the corresponding

25 Because many base analogs are mutagenic when incorporated into DNA, i

26 Complementary ODNs substituted with these base analogs are referred to as SBC or selectively bindi

27 These tetrazole based analogs are highly potent and show selectivity tow

28 A new series of theophylline-based analogs as potent ALDH1A1 inhibitors is described.

29 using chemically synthesized RNAs containing base analogs at each of the five positions.

30 ent kinetic analyses of promoters containing base analogs at positions -10 and -11 have provided supp

31 isolated mitochondria more than their lysine-based analogs, but overall toxicity was decreased, likel

32 e platform enables possible avenues for wave-based, analog computations for general linear algebraic

33 amaterial platform, our wave-based, material-based analog computer may provide a route to achieve chi

34 paradigm that carries the potential of wave-based analog computing to the realm of near-speed-of-lig

35 sJ(8)I(4)), we show that the role of CysJ in base analog detoxification is unique and independent of

36 low-voltage polymer transistors for solution-based analog electronics that meets performance and powe

37 Some of the base analogs enhanced third strand binding to the target

38 PRTase activities were not sensitive to any base analogs examined, with the exception of 8-azaguanin

39 over 5 orders of magnitude for the series of base analogs examined.

40 Fluorescent base analogs (FBAs) are powerful probes of nucleic acids

41 f extrinsic fluorophores such as fluorescent base analogs (FBAs), which mimic the native bases but ha

42 icits produced by irradiation using a ground-based analog for exposure to cosmic rays.

43 tive mechanisms to remove such non-canonical base analogs from DNA precursor pools.

44 suggest a general model for excluding purine base analogs from DNA.

45 cond crystal structure of EcoRV bound to the base-analog GAAUTC site shows that the 50 degrees center

46 Nucleoside, nucleotide, and base analogs have been in the clinic for decades to trea

47 ed by the nfi gene, initiates removal of the base analogs hypoxanthine and xanthine from DNA, acting

48 Earth-based analogs, including bed rest, dry immersion, and pa

49 ore 2-aminopurine or 6-methylisoxanthopterin base analogs incorporated at loop-positions of quadruple

50 ransferase to DNA containing abasic sites or base analogs incorporated at the target base.

51 l DNA precursors to prevent incorporation of base analogs into DNA.

52 sing order of triplex stabilization by these base analogs is: opposite the 'inverted' base pairs, for

53 Mutants of M. voltae resistant to base analogs lacked PRTase activity.

54 We here use our site-specific base analog mapping approach to study the interactions a

55 00 (6.13%) and the naphthalene diimide (NDI)-based analog NDI-IDT (2.19%).

56 6-MI is a base analog of G and spectroscopic signals obtained from

57 the two fundamental requirements of a vector-based analog of a decentralized cognitive map: Home vect

58 l)benzo[B]thiophene (APBT) is a novel sulfur-based analog of API and APB that has not been pharmacolo

59 enzo[beta]thiophene (APBT) is a novel sulfur-based analog of API and APB that has not been pharmacolo

60 Summary statistics-based analogs of PolyPred and PolyPred(+) attained simil

61 A non-polar 4-methylindole base analog opposite F had a <2-fold effect on the incis

62 toxin, an N,N,O-trisubstituted hydroxylamine-based analog, or hydroxalog, of the cytotoxic marine nat

63 A PTHrP-based analog ([p-benzoylphenylalanine1, Ile5,Arg(11,13),

64 Fluorescent base analogs placed at positions -2 and -1 of the promot

65 gs suggest that site-specifically positioned base analog probes can be used to characterize the molec

66 ure of mPGES-1 in complex with a glutathione-based analog, providing insight into mPGES-1 flexibility

67 ir function, MSH2 serves as a sensor for DNA base analogs-provoked DNA replication errors and binds t

68 A new fluorescent base analog, pyrrolo-deoxycytidine (PdC), can now be rou

69 roach using a locally mismatched fluorescent base analog reports on the local structure of the hetero

70 ly occurring nucleic acids, oligomers having base analog residues can be readily quantified by GPA.

71 Base analog studies suggest that IntDOT may make specifi

72 ircular dichroism spectroscopy indicate that base analog substitution can alter DNA helical geometry,

73 ns have properties, including a tolerance of base analog substitutions that tend to eliminate major g

74 lutional neural network (CNN) on a memristor-based analog system on a chip (SoC).

75 When a 4-thiouracil (4sU) base analog that allows only imperfect base pairing with

76 of myriocin, a naturally occurring sphingoid base analog that causes immunosuppression by interruptin

77 be possible to rationally design a modified base analog that is efficiently incorporated by RT but s

78 leotide incorporation when 3-deazaguanine, a base analog that lacks the ability to form minor-groove

79 gy of anticancer nucleoside, nucleotide, and base analogs that are FDA-approved and in clinical devel

80 odified DNAs will require the development of base analogs that pair strongly to NitrocH or sC.

81 g properties of Fis-DNA complexes containing base analogs that the 2-amino group on guanine is the pr

82 ly and empirically to its two closest tensor-based analogs, the truncated high-order SVD and the trun

83 erroelectric field-effect transistor (FeFET)-based analog weight cell with a two-terminal stochastic

84 Eight base analogs were tested as third strand residues in oth

85 a cells against the apoptotic effects of the base analog, whereas the involvement of mARC1 in reducti

86 activity of these reporters with pyrimidine-based analogs will allow for the safe elimination of tra

87 theoretical study has identified that the Zn-based analogs would be expected to facilitate enhanced a