ライフサイエンスコーパス: base selection

1 t (i.e., in the absence of space- and object-based selection).

2 even error-prone DNA polymerases function in base selection.

3 ith the replicating base pair, thus relaxing base selection.

4 cile extrusion from the helix in its damaged base selection.

5 ct is not a spatially global form of feature-based selection.

6 ndicating that DETC development involves TCR-based selection.

7 This was not due to a TCR-based selection.

8 red from cells that have undergone lethality-based selection.

9 ce of survival and reproduction, and fitness-based selection.

10 n to replace nonessential genes through Cas9-based selection.

11 e activation (CRISPRa) and high-avidity bead-based selection.

12 half of patients respond even after molecule-based selection.

13 f affinities and lack signatures of affinity-based selection.

14 population indicate high potential of genome-based selection.

15 selection tool as a substitute for phenotype-based selection.

16 eographic patterns may go beyond temperature-based selection.

17 valuated using information-driven and expert-based selection.

18 eaths (52 600 vs. 55 000) compared with risk-based selection.

19 cyclic re-entry to ensure efficient affinity-based selection.

20 ide library that was formatted for autocrine-based selection.

21 nded effects and nearly twice as much MHC-II based selection.

22 cycles of targeted mutagenesis and affinity-based selection.

23 such selection mechanisms: space- and object-based selection.

24 small molecule were identified by microarray-based selection.

25 zes directed domain shuffling and rapid cell-based selections.

26 veral cell cycles in the absence of affinity-based selection(8-13).

27 on via Fusion-Inhibited Carbamoyltransferase-based Selection), a bacterial selection system, which en

28 eered PKS design by learning from laboratory-based selection; adoption of DNA design software and aut

29 anning and enzyme-linked immunosorbent assay-based selection afforded a panel of nine scFv-phage clon

30 Pyr-thn-based selections against the deubiquitinase USP15 yielde

31 Simulation result indicates that HD-based selection algorithm is effective in recognizing ke

32 RNA recombination with a powerful host range-based selection allowed by the interspecies chimeric vir

33 l and error selection process to a knowledge-based selection, allowing the rational design of differe

34 were essential in elucidating mechanisms of base selection and exonuclease proofreading.

35 567) is a key determinant of the fidelity of base selection and that the Pol and Exo functions are st

36 provide a conceptual framework for rationale-based selection and combination of anticancer drugs for

37 gut microbiotas include chance events, host-based selection and interactions among microorganisms wi

38 This algorithm integrates rule-based selection and machine learning (ML) in a two-step

39 sh N(-) B cells in adult life via repertoire-based selection and suggest the possibility of a TdT-def

40 has great influence on the success of genome-based selection and that confounding effects between the

41 h were used to examine the effect of feature-based selection and the competitive influence of a secon

42 forming a conceptual framework for rationale-based selection (and combination) of immunosuppressive a

43 at was part of the same object (i.e., object-based selection), and at an uncued location that was par

44 of stochastic diversification and immunogen-based selection, and as a result is heavily dependent on

45 i-ty-based Selection, Prediction Probability-based Selection, and Competence-based Active Learning, h

46 standing of selection criteria, disprove sex-based selection, and elevate prestige value as a more cr

47 filing, genome-wide knockout studies, stress-based selection, and the use of inhibitors.

48 The results suggest that feature-based selection applies to stimuli at ignored peripheral

49 In this study, we used a novel, cell-based selection approach for isolating 'cell-type specif

50 Thus, this novel fluorescence-based selection approach simplifies the generation of ap

51 Using a target-based selection approach, we developed oligonucleotide a

52 scovery typically uses hybridoma- or display-based selection approaches, which lack the advantages of

53 rstanding the direct impacts of ecologically based selection, as well as the indirect effects due to

54 e polymerase chain reaction (PCR) and a cell-based selection assay to produce Cat*, which exhibits gr

55 In this study an in vitro PCR-based selection assay was used to identify sequences bou

56 cillatory responses, suggesting that feature-based selection at ignored locations during visual searc

57 et detection at a cued location (i.e., space-based selection), at an uncued location that was part of

58 as length distribution, paired distance, and base selection bias of vsiRNA sequences reflect differen

59 f the same object (i.e., resulting in object-based selection), but little is known about the relation

60 d type and suggest that enhanced fidelity of base selection by a polymerase active site can result in

61 ase is achieved in a multiplicative process: base selection by its polymerase activity and removal of

62 One round of mRNA display-based selection can be accomplished in ~7 d.

63 We hypothesized that visual, color-based selection can be an effective strategy to identify

64 The results indicate that predation-based selection can increase the influence of distant ne

65 ic flounders is the trait under ecologically based selection causing reproductive isolation, directly

66 geochemical processes subject to persistence-based selection conform with the historicity of the geoc

67 of epistasis that are shaped by ecologically based selection could be common and central to understan

68 Life-gained-based selection could maximize the benefits of lung canc

69 g MS-, physical-chemical, and chromatography-based selection criteria including HRMS/MS fragmentation

70 ive clinical trials begin to adopt molecular-based selection criteria to guide targeted therapies.

71 e applied to the models with the GRAPA curve-based selection criteria.

72 The observed distinct mechanisms of base selection demonstrated for members of the uracil gl

73 In this study, machine learning-based selection did not improve performance compared wit

74 relates to potential mechanisms for affinity-based selection during the reaction.

75 incorporating this information, the entropy-based selection (EBS) scheme is useful for selecting an

76 ation steps through the use of hybridization-based selection embedded in the assembly process.

77 face of Galphas and argues that mRNA display-based selection/evolution is a powerful route for target

78 demonstrate this notion, we preformed growth-based selection experiments at nonpermissive temperature

79 as identified as an important determinant of base-selection fidelity.

80 50 to 80 years to estimate outcomes of risk-based selection for CT lung screening, assuming screenin

81 pattern highly indicative of tissue-context-based selection for ecDNAs, linking their genomic conten

82 Compared with treating all patients, CTP-based selection for EVT at the optimised ischaemic core

83 ation of new lineages under host- or element-based selection for function, in either case followed by

84 ion method, named, iterative non-local prior based selection for GWAS, or GWASinlps, that combines, i

85 Using a transposon-based selection for increased hemA expression in the abs

86 ariants identified could help improve marker-based selection for pancreas disease resistance.

87 of infection and suggest that genetic marker-based selection for resistance to bTB has the potential

88 reated by combination of design and reaction-based selection from libraries.

89 binding site previously identified by a PCR-based selection from random oligonucleotides by using re

90 ine-induced cells, and low-dose chemotherapy-based selection further increased engraftment.

91 During base selection, human Pol(iota) preferred T-G base pairi

92 t to non-covalent DNMT1 inhibition, activity-based selection implicates numerous regions outside the

93 resent a paradigm shift for the mechanism of base selection in the Pol X family of DNA polymerases.

94 zF72 was generated and subjected to a growth based selection in a chorismate mutase deficient strain.

95 fundamentally different concepts for genome-based selection in landrace-derived maize populations, o

96 mechanisms appear to operate during feature-based selection in much the same manner as has been show

97 Genomic selection was "superior" to marker-based selection in terms of response to selection for yi

98 in the dark zone (DZ), followed by affinity-based selection in the light zone (LZ).

99 in the dark zone (DZ), followed by affinity-based selection in the light zone (LZ).

100 d the effects of reward on space- and object-based selection in the same experimental setting.

101 regulators of p53, we have used a phenotype-based selection in which a total cDNA library in a retro

102 We observed that global feature-based selection, indexed by the brain response to unatte

103 , however, whether and how early oscillation-based selection influences speech perception.

104 30(th), 2020 were stratified through a risk-based selection into a non-adherent group (NA-group) if

105 A crucial factor determining object-based selection is the grouping between visual elements.

106 imary electrophysiological marker of feature-based selection is the N2pc, a lateralized posterior neg

107 Cell competition (CC) is a fitness-based selection mechanism that results in increased prol

108 to investigate DNA polymerase catalytic and base-selection mechanisms.

109 color search, but regard spatial and feature-based selection mechanisms as independent.

110 Dendritic cell maturation and TCR affinity-based selection mechanisms control the recruitment and e

111 attention and rivalry rely on shared object-based selection mechanisms.

112 We evaluate this activity-based selection method against a traditional screening a

113 We have developed an activity-based selection method to evolve DNA polymerases with RN

114 such enzymes, we have developed an activity-based selection method which isolates polymerase mutants

115 site, identified by a combinatorial activity-based selection method, within genomic and subgenomic RN

116 In summary, we describe a novel cell-based selection methodology that enables the identificat

117 The correlation-based selection methods achieved the best single-cell ma

118 elements of both modular design and activity-based selection methods typically used for generation of

119 Capillary electrophoresis-based selection of aptamers for protein targets requires

120 t and validate a scoring system for evidence-based selection of bariatric and metabolic surgery proce

121 ation and updates previous models of spindle-based selection of cell fate during mitosis.

122 However, epitope density-based selection of cells with different avidities was ev

123 is paper are the starting point for pedigree based selection of cultivars with high levels of resista

124 e advocate for a context-dependent, evidence-based selection of cut-off methodologies, informed by pa

125 rationally design capillary electrophoresis-based selection of DNA aptamers for protein targets.

126 ry between and within cancer types, evidence-based selection of drugs is crucial for targeted therapy

127 Although risk-based selection of ever-smokers for screening could prev

128 Persistence-based selection of feedbacks can help us understand how

129 CC-based selection of fit cells may also drive selection of

130 d CD8alphabeta(+) T cells, mediated affinity-based selection of memory precursor cells.

131 r cells, demonstrate preferential repertoire-based selection of N(-) B cells into the MZ.

132 analyses did not yield any scenarios for CTP-based selection of patients for EVT that were cost-effec

133 pportunity for genomics- and transcriptomics-based selection of patients for rationally designed ther

134 VID-19 pandemic, but also to inform evidence-based selection of personal protection equipment and inf

135 ful procedure that permits an unbiased trait-based selection of plant samples based on such phenotypi

136 conditions is a perfect complement for IFCE-based selection of protein binders from oligonucleotide

137 To inform the evidence-based selection of specific meditation types it is cruci

138 etention in SFC can be used for the evidence-based selection of stationary phases suitable for the se

139 f our approach is false discovery rate (FDR) based selection of strongly connected genes (SCGs), by w

140 tic machinery with implications for genotype-based selection of targeted therapeutics in SCLC patient

141 In this study, structure- and computation-based selection of the predicated VDAC1 dimerization sit

142 The reports further suggest that the marker-based selection of the tumor cell population will facili

143 ll model of how the GC reaction and affinity-based selection operate.

144 We posit that feature-based selection operates by implementing multiple mechan

145 After phage-based selection, our final SpySwitch allows purification

146 We found that the model-based selection outperforms the conventional inclusion c

147 ing funnel" as well as prioritizing affinity-based selections over epitope-based selections, result i

148 ASPECTS-based selection paradigms for late presenting and wake-u

149 ection when investigating seasonal behaviour-based selection patterns.

150 We developed a cell-based selection platform for TCR ligand discovery that e

151 ese spike mimics no longer required antibody-based selection, positive or negative.

152 The proposed methods, namely Similari-ty-based Selection, Prediction Probability-based Selection,

153 a were resistant, indicating strong antibody-based selection pressure.

154 rom the STS ACSD according to the likelihood-based selection probabilities to achieve similar STS pre

155 this problem, we have developed a population-based selection procedure to increase aggression in Dros

156 d WIN protein in a polymerase chain reaction-based selection procedure.

157 The cell-based selection process is simple, fast, straightforward

158 We find that the time-course of the object-based selection process is well explained by a 'growth-c

159 minate the use of helper phage from phagemid-based selection protocols; reducing the amount of techni

160 population-level signature of global feature-based selection reflects a sequence of hierarchically or

161 The structure suggested a mechanism of base selection relying on Loop1 and taking instructions

162 izing affinity-based selections over epitope-based selections, result in lead antibody panels lacking

163 Proximity based selections resulted in a population of antibodies

164 These findings indicate that object-based selection results from an object-sensitive reorien

165 spatial resolution in TERS and the gradient-based selection rule.

166 lter intein specificity, we developed a cell-based selection scheme to evolve split inteins that spli

167 Further, we apply a pH-based selection scheme to measure the effect of mutation

168 Using a yeast-based selection scheme, we isolated derriere, a novel TG

169 In contrast, risk-based selection screening of the same number of ever-smo

170 nT(reg) TCR repertoire is shaped by affinity-based selection, similar to conventional T cells.

171 oral data to determine how space- and object-based selection simultaneously evolve under conditions t

172 ng resulting from a spatial cue (i.e., space-based selection) spreads to uncued locations if those lo

173 tence), G12 outperforms the allele frequency-based selection statistic, SweepFinder2, previously used

174 Targeted therapy arms that used a biomarker-based selection strategy (n = 57 trials) were associated

175 A risk-based selection strategy and a rescue therapy may limit

176 We used a high throughput, cell-based selection strategy to screen a BSB library for seq

177 ifunctional gp17, we developed an expression-based selection strategy to select for mutants that are

178 mutagenesis and a green fluorescent protein-based selection strategy.

179 arental rodent antibody into a phage display-based selection strategy.

180 s of targeted agents did not use a biomarker-based selection strategy.

181 Importantly, this nonantibiotic-based selection system allows the use of cheap and widel

182 describe the process of creating an evidence-based selection system and examine its impact on screeni

183 Given the large library sizes our bacterial-based selection system can handle, this method should pr

184 t the development and application of a yeast-based selection system designed to functionally interrog

185 By combining a previously developed FACS-based selection system for functional expression with ul

186 he efficacy of the non-invasive fluorescence-based selection system is promising for its application

187 thod that makes use of a powerful host range-based selection system.

188 of this phenotype, we developed an arginase-based selection system.

189 ss, making it more general than biologically based selection systems because it is not limited to rea

190 cally not amenable to traditional antibiotic-based selection systems, and may be used in combination

191 ific tools, including promoters for reporter-based selection systems, that we employed to improve lov

192 An entropy-based selection test is presented that explicitly takes

193 lygenic resistance and field- vs. laboratory-based selection, the application of molecular cloning to

194 pansion, somatic hypermutation, and affinity-based selection, the combination of which results in the

195 ate progressive but discontinuous repertoire-based selection throughout B cell development supporting

196 he G185V substitution was used in a function-based selection to identify mutations that would further

197 impede anaerobic growth, followed by growth-based selection to isolate suppressor mutants that resto

198 results demonstrate the potential for marker-based selection to optimise trait trade-offs and enhance

199 Here, we adapted a phage display library-based selection to screen and identify binding peptides

200 fit kinetic traces using convenient browser-based selection tools, ameliorating tedious steps involv

201 rgo somatic hypermutation (SHM) and affinity-based selection toward antigen in activated germinal cen

202 ralleled advantage over traditional pedigree-based selection (TS) methods by reducing the time commit

203 ing bacteria and methanogens indicate energy-based selection typical of anoxic marine sediments, 5-15

204 dinated network of water molecules acting in base selection upstream of the GGAA core and the structu

205 Imaging-based selection, used in some of the recent trials to ex

206 or the isolation of bona fide hiPSCs in FACS-based selection using an optimized combination of cell s

207 le between these two strategies, using model-based selection when recent wins signal the appropriaten

208 ning theory to achieve this kind of identity-based selection, whether and how these architectures are

209 s genetic modifications to tighten lethality-based selection while simultaneously boosting efficiency

210 Reaction-based selection with 1,3-diketones was performed to trap

211 Toxin-based selection works in both cancer-transformed and non

212 015, the analysis estimated that life-gained-based selection would increase the total life expectancy

213 MS analysis of the suspension after density-based selection yielded a sensitivity of 72.1% and a spe

214 FLoSS-based selection yields families with exceptional longevi