ライフサイエンスコーパス: baseline

1 abling ctDNA detection in 96% of patients at baseline.

2 among HIV-positive MSM without dysplasia at baseline.

3 is defined using changes in creatinine from baseline.

4 f T2D, cardiovascular disease, and cancer at baseline.

5 ated pituitary dome depression compared with baseline.

6 d to PCIT-ED vs. 55 assigned to waitlist) at baseline.

7 erences among patients who had had angina at baseline.

8 d women aged 64.44 (SD 8.49) y on average at baseline.

9 o remain more similar to their pre-treatment baseline.

10 986-2016) who were free of CVD and cancer at baseline.

11 ed depressive symptoms and no CVD history at baseline.

12 ne, or increase in glaucoma medications from baseline.

13 s increase their activity level, compared to baseline.

14 rrow Transplant (FACT-BMT) score relative to baseline.

15 general cognitive function were collected at baseline, 12-week, and 24-week.

16 Methods: One hundred forty baseline (18)F-FDG PET/CT scans were selected from U.K.

17 gression among 15,612 adults aged 40-78 y at baseline (1993-1997) and followed up over 1998-2000 (mea

18 In 8,935 participants at the baseline (1996-1998) from the Atherosclerosis Risk in Co

19 most prevalent in both HIV-negative (38% at baseline, 30% at the follow-up visit) and HIV-positive (

20 A total of 6632 patients were included; at baseline, 3352 (50.5%) did not have diuretics, 2195 (33.

21 he follow-up visit) and HIV-positive (27% at baseline, 35% at the follow-up visit) women.

22 Rectal swabs were collected at baseline, 36 months, and 48 months for analysis of the p

23 Of the 7 intubated at baseline, 4/7 were fully recovered off oxygen, 2/7 were

24 individuals developed dementia (mean age at baseline = 57.5 +/- 5.9 years, 58% women).

25 sample included 252 745 women (median age at baseline, 57 years) with 38% self-reporting use of powde

26 Baseline 8-OHdG concentrations were also associated with

27 .4 (22.7) minutes in the intervention group (baseline-adjusted difference [95% confidence interval] -

28 oplasia at each subsequent examination after baseline, adjusting for multiple colonoscopies within in

29 heter ablation patients, regardless of their baseline AF type.

30 ork Heart Association class were assessed at baseline (after randomization) and at each follow-up vis

31 Hemodynamics were evaluated at baseline, after pulmonary embolism and after each dose b

32 When adjusted for baseline age, socioeconomic status, and self-rated gener

33 oidism, adjusting for depressive symptoms at baseline, age, sex, education, and income (PROSPERO CRD4

34 At baseline, all 5 biomarkers were higher than published re

35 ic mean FIA[-SD, +SD](%) from doses given at baseline, alternate days, and every third day did not di

36 paired group, younger age (P = 0.02), higher baseline amyloid PET (P = 0.05), APOE epsilon4 (P = 0.05

37 AH inhibition produced a 10-fold increase in baseline anandamide.

38 Endoscopy was performed at baseline and 1-week post-procedure.

39 enic progressive aphasia) that had undergone baseline and 1-year follow-up MRI and flortaucipir PET.

40 The VA at baseline and 12 months post-RRD repair was recorded.

41 cted (lesional and nonlesional skin) between baseline and 12 weeks.

42 interproximal bone height were evaluated at baseline and 12-months post-therapy.

43 Between baseline and 16 weeks of treatment, the following measur

44 hree participants (33%) had NC impairment at baseline and 2 (22%) remained impaired at week 24.

45 t 26 weeks in the CGM group and 8.9% at both baseline and 26 weeks in the BGM group (adjusted between

46 ithine, polyamines, and acetyl polyamines at baseline and 26 wk of intervention were measured by an u

47 immunoglobulin G antibody concentrations at baseline and 4-8 weeks postvaccination.

48 ry and expiratory chest CT and spirometry at baseline and 5-year follow-up.

49 Mean HbA1c was 8.9% at baseline and 8.5% at 26 weeks in the CGM group and 8.9%

50 and volumetric measurements were recorded at baseline and after 1 and 12 months.

51 2) 18 patients with ajmaline-induced BrS (at baseline and after ajmaline), in whom epicardial potenti

52 antagonist, montelukast, as well as between baseline and after follow-up.

53 ts were assessed in nasal mucosa biopsies at baseline and after treatment.

54 OCT measurements, taken at baseline and annually, were graded by reading center gra

55 ume (BV/TV%) and iliac crest were similar at baseline and at month 4.

56 study design, PET/CT scans were performed at baseline and before starting maintenance (premaintenance

57 Besides other baseline and clinical differences, EE more frequently af

58 Cognitive function was assessed at baseline and during follow-up using the Montreal Cogniti

59 rticipants with mild cognitive impairment at baseline and either no neuritic plaques (i.e. primary ag

60 also impaired in PSW compared to controls at baseline and following IL-33 stimulation.

61 inhibitory neurons displaying highest FRs at baseline and following the stimulus.

62 ehavior was assessed in patients with AUD at baseline and for 4 weeks following memory tests.

63 anzania from 50 communities were followed at baseline and for 6 months after MDA.

64 The presented method showed a stable baseline and high-resolution separation of the standards

65 After adjusting for imbalances in baseline and implementation factors, the incidence of ma

66 , which is based on SUV(max) changes between baseline and interim scans.

67 to PCIT-ED (n = 60) or waitlist (n = 58) at baseline and late positive potential (LPP) data from 99

68 RLCQ scores and poorer cognitive function at baseline and lower rates of cognitive decline.

69 5.1-5.9) years, 8828 participants provided a baseline and one or more follow-up MoCA or DSST scores,

70 Baseline and periprocedural characteristics were equal b

71 They underwent baseline and postprandial MRI scans, symptom questionnai

72 7 dipyridamole and 18 placebo recipients had baseline and week 12 data available for analyses.

73 tained with 18F-flutemetamol (Vizamyl(R)) at baseline and Week 78.

74 FVIII activity was measured at baseline and weekly thereafter.

75 pared for all patients before the procedure (baseline) and on postoperative day 90: MRD1, Ocular-Surf

76 t (n = 23) ADHD completed the bandit task at baseline, and after methylphenidate or placebo in counte

77 Among women with undetectable baseline anti-GBS levels, postdose 2 GMCs in previously

78 Baseline antibody status was determined by anti-spike (p

79 ed novelty-induced locomotor activity, lower baseline anxiety, and motivational deficits in operant c

80 Here, we studied how baseline assessments of in vivo tau pathology (measured

81 betic Retinopathy Study (ETDRS) letters from baseline at 6, 12 and 18 months.

82 ortly after image onset but relaxing back to baseline at different rates.

83 ement in Eczema Area and Severity Index from baseline at week 16.

84 Mean increases in CD4 counts from baseline at week 96 were 205 cells per muL (SD 191) in t

85 nct PH domain structural changes compared to baseline autoinhibited Akt.

86 g, this combined dataset represents a global baseline available for interrogation by future microbial

87 ents were younger age (P < 0.0001) and worse baseline BCVA (P < 0.0001).

88 After adjusting for age, gender, baseline BCVA and AMD subtype, A (protective) allele of

89 For baseline BCVA and CST, Pearson correlation coefficients

90 In total, 1.5T MRI images were acquired at baseline before commencing clozapine and again after 6 m

91 sleep such that students with shorter TIB at baseline before the first COVID-19 cases emerged locally

92 We assessed associations between baseline biomarkers, IRIS, immune recovery at week 48, a

93 Larger scars at baseline but not changes over time were associated with

94 sites which had presented with recession at baseline but were not treated showed a significantly mor

95 is undetectable in the adult mouse heart at baseline, but mRNA and protein are induced after ischemi

96 60 SZ individuals demonstrated that COPD at baseline, but not former smoking or AAT concentrations,

97 t health centers met the Healthy People 2020 baseline, but opportunities for improvement remain and t

98 Mean diaphragm thickness increased from baseline by 7.8% at 24 hours (p = 0.022) and 15.0% at 48

99 with other aortic pathologies and diminished baseline cardiac function.

100 D4 deletion in cardiomyocytes did not affect baseline cardiac size or function in young adult mice.

101 After excluding participants with baseline cardiopulmonary diseases, stroke and cancer, 17

102 independently lower among participants with baseline CD4 count >=500 cells/uL (3.3%) compared to tho

103 n the non-randomised cohort died; the median baseline CD4 count for participants who died was 11 cell

104 Th1 phenotype were the predominant subset at baseline, cells with phenotypic and transcriptional char

105 luspatercept and 76 to receive placebo; the baseline characteristics of the patients were balanced.

106 Baseline characteristics were similar between treatment

107 Baseline characteristics, including severity of pain and

108 In a multivariate model including baseline characteristics, only receiving a disability gr

109 Responses were similar regardless of baseline characteristics.

110 Baseline circulating concentrations of hexose monophosph

111 ml/min per 1.73 m(2) and >=25% decline from baseline, CKD-related hospitalization or death, or ESKD.

112 sity scores calculated on the basis of their baseline clinical and demographic data.

113 pensity-score weighting, the distribution of baseline clinical and radiological variables was similar

114 n-school clustering, minimisation variables, baseline cluster-level score of the outcome, and sociode

115 ductions were also greater in subgroups with baseline coagulation biomarker levels at or above median

116 icant association with cognitive function at baseline, cognitive decline or with conversion rates to

117 amined the risks of CRC and related death by baseline colonoscopy adenoma findings.

118 h high-grade dysplasia (HGD) colon polyps at baseline colonoscopy remains unclear.

119 We conducted a baseline community-based survey followed by a cluster ra

120 mption of 1 + servings per week of yogurt at baseline, compared to no yogurt consumption, was associa

121 At baseline, compared with control subjects, CHR individual

122 es from nonresponders (P = .04) and distinct baseline composition (P = .04), but no specific marker t

123 deforestation affects climate is the lack of baseline conditions (i.e., prior to human disturbance) o

124 s were then retested in the task, under both baseline conditions and following administration of estr

125 hose of static culture conditions under both baseline conditions and with exposure to ST enterotoxin

126 nment and interactions between treatment and baseline covariates.

127 Baseline D2/3 receptor availability (P = 0.02) and dopam

128 l Rit2 knockdown in DAergic neurons impacted baseline DAT surface:intracellular distribution in DAerg

129 iversity and inclusion within SER to provide baseline data for future evaluations of Society initiati

130 We obtained baseline data on body mass index (BMI), smoking, educati

131 7% vs 23.1% p = 0.04) despite overall larger baseline defect size (32.7 +/- 19.5 mm(2) vs 21.5 +/- 10

132 We estimated the association between baseline demographic characteristics and time to ART ini

133 patients registered before 2018), including baseline demographics, donor, biochemical and clinical d

134 Data were collected on baseline demographics, systemic and ocular comorbidities

135 , 4.1-19.2]; P=0.01) in a model adjusted for baseline demographics.

136 Baseline differences in demographic, clinical, socioecon

137 After accounting for baseline differences, at study end the proportion of peo

138 se with/without anxiety after accounting for baseline dissimilarities in symptom scores (all p(intera

139 P = 0.014), and mean FIA [+/-SD](%) from the baseline dose [23.3 (10.9)] was greater than that from t

140 This remained 100-fold lower than baseline during the 3 year-treatment period and 10-fold

141 there was no significant association between baseline eGFR <60 ml/min per 1.73 m(2) and risk for deme

142 f-reported race (Black, White, or other) and baseline eGFR with AKI incidence among patients who unde

143 /90 mm Hg, higher glycated hemoglobin, lower baseline eGFR, and higher baseline urine albumin/creatin

144 e, sex, diabetes, treatment with an ARNI and baseline eGFR, but suggested treatment-by-subgroup inter

145 Lower baseline eGFR, proton pump inhibitor use, and combinatio

146 Baseline electrocardiographic, computed tomography, and

147 ly if India follows the current legislation (baseline) emission pathway.

148 ertugliflozin was observed in 3 populations: baseline estimated glomerular filtration rate <60 mL.min

149 In Hubei, the baseline estimates were as follows: CFR 2.4% (95% credib

150 eyes with 4-year follow-up, VA changes from baseline (ETDRS letters) were least squares means of +1.

151 n magnetic resonance images were obtained at baseline, every 3 days after exposure for 2 weeks, and t

152 This effect was stronger in muscles with baseline FF below the mean +/- standard deviation of una

153 We found that deep layer neurons show higher baseline firing rates (FRs) in GC with deep-layer inhibi

154 o image onset, showing large deviations from baseline firing shortly after image onset but relaxing b

155 ctional magnetic resonance imaging, but only baseline focal hippocampal atrophy predicted progression

156 Between-group differences in change from baseline for all other scales were not significant.

157 he first empirical evidence and an important baseline for ingestion of microplastics and other anthro

158 ina frequency was increased by 13.7 units at baseline ([Formula: see text], 13.7 [95% CI, 6.3-21.7];

159 not trophic status or body size, is the best baseline from which to predict organismal body nutrient

160 factors in addition to GI and genitourinary baseline function, with higher scores representing bette

161 parental control) AKR mice were assessed for baseline gastritis and progression to metaplasia.

162 w-up (threshold of TBR reduction relative to baseline, >=10%; accuracy, 82%; P = 0.004).

163 symptom severity and breath tests results at baseline (H(2) and/or CH(4) >= 15 ppm).

164 Even eyes that were severely ischemic at baseline had no significant changes in RNP area 1 year a

165 dividuals with only 1 or 2 small adenomas at baseline have a low risk of advanced neoplasia over 10 y

166 ts without persistent opioid use returned to baseline health care spending within 6 months, regardles

167 easuring HVPG response only if the patient's baseline HVPG is over 16 mm Hg improves detection of hig

168 This baseline hypo-connectivity for non-remitters also distin

169 Thus, miRNA assessment at baseline identifies associations with C-peptide and stra

170 ross individuals, which may be partly due to baseline immune variations.

171 on females is dependent on the component of baseline immunity.

172 e aortic stenosis undergoing TAVR, even with baseline impaired eGFR, CKD stage is more likely to stay

173 Symptoms were present at baseline in 120 (60%); 20 (10%) developed symptoms durin

174 of worst daily abdominal pain compared with baseline in at least 4 weeks.

175 s achieving a 50% or higher improvement from baseline in F-VASI (F-VASI50) at week 24, assessed in th

176 tum microbiota showed greater deviation from baseline in ICS nonresponders than in ICS responders.

177 secondary outcomes included the change from baseline in itch-related quality-of-life measures, the p

178 Changes from baseline in most lipid parameters also favored DOR.

179 The primary endpoint was week 12 change from baseline in PASI score.

180 The difference at day 85 in the change from baseline in the CSF SOD1 concentration between the tofer

181 progressive MS at 30 years were presence of baseline infratentorial lesions and deep white matter le

182 or guideline-concordant duration) during the baseline, intervention, and postintervention periods, re

183 infected woodchucks; the identification of a baseline intrahepatic transcriptional signature associat

184 ariable logistic regression analysis, higher baseline IOP predicted higher odds of POD1 IOP spike >40

185 The two groups had similar FLD at baseline; it progressively improved up to month 18 in bo

186 Antibiotic prescribing was compared in the baseline (January-June 2016), intervention (January-June

187 erage sample size 136,000), we show that the Baseline LD model is more realistic than other existing

188 The mean baseline LDL cholesterol level in the two groups was 255

189 Anemia incidence increased with rising baseline levels of high-sensitivity C-reactive protein (

190 esponse to facial affect stimuli returned to baseline levels while positive affect remained elevated,

191 egression model adjusting for the effects of baseline MD and age, cataract extraction, interactions,

192 In predicting 90-day mortality, baseline mean airway pressure demonstrated similar discr

193 Baseline measurement was performed with patients supine

194 recruited from February 2004 to May 2006 for baseline measurements, and follow-up was performed 48 mo

195 art rate variability (HRV), and the averaged baseline measures of HRV to heart rate recovery (HRR) fo

196 After study enrollment and baseline measures, participants consumed encapsulated hi

197 At baseline, median intake of SSBs was 472.1 mL/wk (IQR: 19

198 At baseline, median MRI-PDFF was 16.3% and MRE-stiffness wa

199 At baseline, median total area of GA was 13.4 mm(2) and med

200 e significantly narrower than of a two-stage baseline method that first estimates the variance compon

201 ability to infection was not associated with baseline microbiome but was reproduced in mice by preinf

202 at years 2 and 5 were preceded by pixels of baseline MNV.

203 models outperformed the previously published baseline models.

204 On multivariable analysis, baseline mrTD/mrEMVI (extramural venous invasion) status

205 At baseline, MS was 10.4 +/- 5.2 dB (n = 361), and the eMS

206 malignancies, peri-COVID-19 lymphopenia, or baseline neutropenia had worse COVID-19 outcomes.

207 rans 75 years and older and free of ASCVD at baseline, new statin use was significantly associated wi

208 with a history of lung cancer (P < .001), a baseline nodule volume less than 500 mm(3) (P = .03), an

209 NSAID use at baseline, NSAID use during the trial (incident NSAID use

210 achieved SVR, which was not associated with baseline OAT status (P = .33), on-treatment drug use (P

211 p learning algorithm was used to segment all baseline OCT scans.

212 (IOP) >18 mm Hg or not reduced by 30% below baseline on 2 consecutive follow-up visits after 3 month

213 isits: IOP >21 mmHg, IOP reduction <20% from baseline, or increase in glaucoma medications from basel

214 When baseline oscillations are weak, the stimulated area exhi

215 to TT, PT, and PCV serotypes increased from baseline (P < .001 for all antigens) and remained elevat

216 patients in 35 sites were treated; mean (SD) baseline PASI score was 20.8 (7.68).

217 r regression was used to model PCI scores on baseline PCI, treatment, and other factors.

218 During the baseline phase, departmental guidelines advised prophyla

219 Conversely, a log2 higher baseline plasma NfL level was associated with a higher r

220 e = 0.69) and calibration characteristics as baseline plateau pressure and driving pressure.

221 ls with MDD and 22 healthy controls (HCs) at baseline, post-placebo, and post-ketamine.

222 Independent baseline predictors of clinical responder status were lo

223 ET) scans with two different radiotracers at baseline prior to brexpiprazole administration, and agai

224 Baseline PSA was inversely related with recurrence (haza

225 ifferences in body size, blood pressure, and baseline pulmonary capillary wedge pressure between grou

226 ith the level of cognitive ability at age-70 baseline (range of standardized beta-values = -0.178 to

227 Baseline RBANS (82 +/- 17) and BPRS (41 +/- 13) scores w

228 s transitioned abruptly between aberrant and baseline reach kinematics in a dopamine-dependent manner

229 hile survivors had similar CD4 cell count at baseline, regardless of HTLV status.

230 ock size six; 1:1:1) was done, stratified by baseline Richmond Agitation Sedation Scale (RASS) scores

231 3 [SHR, 4.5; 1.59-12.73]) were identified as baseline risk factors for CKD development.

232 y design: phase I, 2-minute resting state at baseline (room air); phase II, 6-minute maternal hyperox

233 Higher baseline SAF was an independent risk factor for CVEs (ha

234 Baseline saliva samples from 17 facilities, cases and co

235 ife) at 2 years; adjustment was made for the baseline score.

236 hs, and the secondary endpoints (efficacy by baseline serostatus, serotype, hospitalised dengue, and

237 t committee made 1 strong recommendation for baseline serum calcium testing, 13 conditional recommend

238 All non-malignant MG was identified in the baseline serum of participants of RIISC.

239 rds models estimated the association between baseline serum retinol quintile and overall and site-spe

240 t cell (MC) activation symptoms and elevated baseline serum tryptase level (MCAS-T) may not necessari

241 A baseline serum tryptase level within the upper normal ra

242 rderline worse vision and thicker maculae at baseline, showed larger CST reductions after 12 months o

243 ntional monocytes and pMos revealed distinct baseline signaling profiles and far greater heterogeneit

244 roup, sensitivity of the highest-performing (baseline) SSD was 81% (95% confidence interval [CI]: 80%

245 n with the anti-spike IgG assay to determine baseline status.

246 Baseline stroke severity adjusted regression model showe

247 PRS and depression when under stress than at baseline, suggesting that MDD-PRS adds unique predictive

248 ho self-reported poor adherence) completed a baseline survey that assessed the following: (1) demogra

249 Three years after the baseline survey, postdisaster social capital and symptom

250 hicker maculae (mean difference, +26 mum) at baseline than those receiving ranibizumab, which were no

251 At baseline, the mean CAL was 9.56 +/- 1.93 mm with a mean

252 patients with negative [TIMP-2]*[IGFBP7] at baseline, those who became positive (>0.3 units) after r

253 At baseline, those who developed ME/CFS had more physical s

254 The mean MSE reduced from -5.39+/-2.30 D at baseline to -0.01+/-0.24 D at 12 months.

255 nnaire overall summary score [KCCQ-OS]) from baseline to 1 month and the composite rate of death or H

256 levels decreased from 26.3 +/- 10.7 ng/mL at baseline to 20.8 +/- 8.1 and 20.8 +/- 8.5 ng/mL at 24 an

257 In study 1, mean change (baseline to 3 mo) in serum vitamin D3 was -0.1 ng/mL in

258 TMVr reduced PASP from baseline to 30 days to a greater than GDMT alone (adjust

259 the short form 36 sum or domain scores from baseline to 5 years, except for the short form 36 role e

260 Medication adherence improved from 59.9% at baseline to 81.3% (P < 0.0001) after completing the SEE

261 severe skin photoaging increased from 42% at baseline to 88%.

262 together, our results provide a quantitative baseline to constrain model-based hypotheses of plant re

263 Mean IOP did not change from baseline to final visit in the overall cohort (16.2 +/-

264 ice was active, walking speed increased from baseline to immediately after the intervention on flat a

265 t was measured, and relative SI changes from baseline to interval scans were calculated.

266 In study 1, the change in EGP (baseline to last hour of EGP measurement) in subjects re

267 Baseline to month 24 data from all randomized study eyes

268 Mean change in square root area of MA from baseline to month 24 was +0.36 mm (95% confidence interv

269 in a statistically significant fashion from baseline to month 3 in all 3 groups by 1.4% to 2.1% (P <

270 r to placebo (average difference change from baseline to week 3 through end of treatment [EOT] in MAD

271 moters serve a critical role in establishing baseline transcriptional capacity through the recruitmen

272 The flow-gradient pattern was determined at baseline transthoracic echocardiography and classified a

273 Most patients had baseline tumor biopsies positive for PD-L1 expression (n

274 the area under the curve (mm Hgxyears) from baseline up to year 30 examination.

275 In the norm-albuminuria cohort (n = 75) baseline UPPod:CR was associated with development of alb

276 1.7 ml/min/1.73m(2)) and norm-albuminuria at baseline, UPPod:CR was associated with eGFR loss rate (P

277 hemoglobin, lower baseline eGFR, and higher baseline urine albumin/creatinine ratio.

278 0.004] for >=7 injections, respectively) and baseline VA of 20 logMAR letters or fewer (adjusted odds

279 Baseline variables in the 98 pomegranate juice and 102 p

280 When adjusted for prespecified baseline variables, the odds ratio for 90-day mortality

281 f clinical events and their correlation with baseline virological and biochemical parameters as well

282 of exudation or proliferation with return to baseline vision (n = 2), stable mild exudation (n = 1),

283 sponse between patient groups with different baseline visual acuities.

284 and postintervention periods, respectively (baseline vs intervention and postintervention, P = .001

285 ion to within 2 lines of pre-endophthalmitis baseline was achieved in 53% of patients at 3 months of

286 , < 0.0001-0.03); improvement at month 18 vs baseline was higher in Cit-B12 than placebo (33% vs 15%,

287 hange in aBSI after treatment, compared with baseline, was significantly associated with OS (P < 0.00

288 We considered 2 outcomes from the baseline wave of the Ten to Men study (Australia, 2013-2

289 For participants without SILs at baseline, we estimated the cumulative incidence and risk

290 reductions in central retinal thickness from baseline were 126.1, 127.1, and 126.9 mum, respectively.

291 Raw data and differences from baseline were analysed in the two groups.

292 of age, and participants who took statins at baseline were compared with those who did not using Cox

293 and not on ART with detectable viral load at baseline were randomly assigned; 666 (51%) were men.

294 status of 0-2, and had measurable disease at baseline were recruited from 35 academic and community h

295 unequivocal evidence of liver metastases at baseline whole-body MRI, two participants were excluded

296 atched control subjects to be symptomatic at baseline with a greater symptom severity score, but this

297 h patisiran were sustained from parent study baseline with treatment in the global OLE (APOLLO-patisi

298 te in persons with risk factors for NAFLD at baseline, with AUROCs reaching 0.83.

299 The estimated baseline WOMAC score for the full sample was 47.5 (95% C

300 lation consists of 250 TAVR patients in whom baseline Zva and follow-up QOL was prospectively assesse