ライフサイエンスコーパス: basic

1 To move forward, we need to return to the basics.

2 1Delta76-86) or a substitution in polymerase basic 2 protein (PB2-D309N).

3 ine and IFN action represented a significant basic advance and a new paradigm in cell signaling.

4 osized EVs within the hour time scale, using basic AFM equipment and skills and only needing freely a

5 However, by the incorporation of basic amine functions at controlled positions in the mod

6 her demonstrated that the positively charged basic amino acid substitution at E367 enhanced the viral

7 tron microscopy structure of the neutral and basic amino acid transport complex (b([0,+])AT1-rBAT) wh

8 tidylserine are found to be similar in GB to basic amino acids lysine and histidine, and phosphatidic

9 Much has been learned about the basic anatomy of the tick's mouthparts and in the broad

10 Therefore, a method involving sequential basic and acidic methanol extractions was developed and

11 t Basic and Advanced Life Support, Pediatric Basic and Advanced Life Support, Neonatal Life Support,

12 The Adult Basic and Advanced Life Support, Pediatric Basic and Adv

13 benefits and challenges of these systems in basic and applied biomedical research are presented and

14 y to immune cells which will facilitate both basic and applied research towards the goal of direct in

15 Both basic and clinical evidence reveal dual roles for GJs, i

16 ffective management of COVID-19 will require basic and clinical investigation and public health and c

17 studying hierarchical processes relevant to basic and clinical neuroscience.

18 ild on this momentum and continue to advance basic and clinical research to develop improved tools an

19 c-base-catalyzed mechanism (E1cB-like) under basic and pH neutral conditions.

20 l (SC) cultures are irreplaceable models for basic and translational research but their use can be li

21 come to have a central and catalytic role in basic and translational research.

22 ction of their target organ are valuable for basic and translational research.

23 cancer have proven to be of great value for basic and translational research.

24 se of partnerships with scientists (that is, basic and translational researchers) and academic collab

25 des insight into its mode of action beyond a basic antibiotic.

26 ation procedure with 8X-30X speedup over the basic approach.

27 ous circulation and short-term survival, and basic assessments of functional and neurological status.

28 We then examine the effect of relaxing some basic assumptions about the ordering of modification.

29 like contacts may call for a reassessment of basic assumptions in cutaneous sensory perception and sh

30 llenging undertaking - coordination of Lewis basic atoms into metal centers often necessitate elevate

31 ify two consensus active site acidic (a) and basic (b) motifs shared across the entire two-barrel nuc

32 nderlying the TOFT offer new perspectives on basic biological phenomena.

33 ese remarkable birds can help us uncover the basic biological processes driving technological progres

34 Advances in our understanding of the basic biology and biochemistry of chromatin structure an

35 ol can be conducted by any researcher having basic biology and chemistry skills in ~3 d.

36 Our results provide new insights into the basic biology of adjuvant-elicited cellular immunity and

37 In this Review, we discuss the basic biology of flaviviruses, their infectious cycles,

38 Seminar, we focus on the role, function, and basic biology of the ECM in both heart development and i

39 cell immunotherapy, our understanding of the basic biology of these cells, including how their number

40 to achieve selectivity, and applications in basic biology or in the clinic.

41 test insights in Wnt signaling, ranging from basic biology to therapeutic implications in cancer, are

42 g to physicians and is considered as defying basic biology.

43 tus of individuals, vaccine development, and basic biology.

44 We also introduce basic biophysical theories of the membrane potential to

45 Here, we investigate the basic brain mechanisms underlying the anxiogenic impact

46 In the present work, we extend a basic branching process by allowing the extinction rate

47 atient management somewhat lags behind these basic breakthroughs.

48 that consumes cellular biomass to regenerate basic building blocks that can fuel anabolic reactions.

49 ernating Cu(bpy)(H(2)O)(2)(2+) and MF(6)(2-) basic building units (space groups: Ti-CS (Pnma), Zr-CS

50 cardiolipin membrane domains via a patch of basic C-terminal residues, and this membrane sequestrati

51 ommon sense in humans is founded on a set of basic capacities that are possessed by many other animal

52 variety of methods have been used to measure basic cardiovascular physiology, spinal oxygenation, mit

53 The basic case of three given genomes is known as the genome

54 ffects on various immediate, underlying, and basic causes of malnutrition certainly contributed to th

55 its close connection with the regulation of basic cell physiology.

56 Lipids are basic cellular constituents playing essential functions

57 zation of cells and their ability to perform basic cellular functions such as division and motility.

58 We propose some basic characteristics that should be reported with any n

59 AP, ORAC), phenolic compounds (UPLC-PDA-FL), basic chemical composition, and sensory quality of sea b

60 o enhance the competencies of early-stage AF basic, clinical, and population health researchers throu

61 cial skills stemmed from the onset of a more basic cognitive ability such as recursive representation

62 lts validate the use of ECoG in clinical and basic cognitive research.

63 In this review, we describe the basic components of the glycocalyx and the glycan moieti

64 zwitterionic compounds but also in acidic or basic compounds with poor permeation.

65 Ketelut-Carneiro and Fitzgerald discuss the basic concepts about inflammasome composition, assembly

66 Practical workshops were useful for learning basic concepts about ultrasound imaging, allowing studen

67 mples are purposely selected for emphasizing basic concepts and mechanistic understanding.

68 We first discuss basic concepts and methods of ANNs.

69 The current review aims to introduce these basic concepts in itch biology and highlight how distinc

70 This article covers the basic concepts of cost-utility analyses and reviews the

71 al inference in psychology fail to meet this basic condition.

72 e that simplifies the process and avoids the basic conditions that can sometimes limit the scope and

73 Under mild aqueous and basic conditions, alpha-substituted enone-aldehydes and

74 r acid conditions, as compared to neutral or basic conditions, supports the contention that role of F

75 can be safely administered in a setting with basic critical care, provided that there is a continuous

76 , cognitive function, physical function, and basic daily life skills are assessed at 3 months and bey

77 Cognitive function, physical function, and basic daily life skills are assessed between 6 and 12 mo

78 Consistent basic data suggest that these same checkpoints are criti

79 The C-terminal basic domain of APC (APC-B) directly nucleates actin ass

80 l does not require specific expertise beyond basic Drosophila genetics and husbandry, and confocal mi

81 strated by the direct determination of model basic drugs (nortriptyline, haloperidol, loperamide, and

82 In this Review, we highlight the basic dynamic mechanisms underlying the synergy between

83 ring and supervision, food security at home, basic economic security at home, free schooling, free sc

84 For projects that exceed a basic economic viability threshold, we identify the ones

85 s in phenotypic traits constrain recovery of basic ecosystem functions (decomposition of organic matt

86 ion trajectories, and allow users to perform basic edits to DNA and RNA designs.

87 fficients that could not be described by the basic electrostatic potential theory or by assuming that

88 ce, the central line of inquiry, animated by basic emotion theory and constructivist accounts, has be

89 is study, we assessed the effectiveness of a basic enriched environment in the chronic phase after ph

90 l ether acceptors while tolerating the Lewis basic environment found in carbohydrates.

91 A basic expectation of evolution by natural selection is t

92 ntly unfair action, and equality, which is a basic fairness principle.

93 In addition, they often employ basic features to train the models in a simple and coars

94 e the synthesis of functional molecules from basic feedstocks.

95 Basic ferryl species have been proposed to facilitate th

96 and healthcare appointments are at odds with basic food and housing needs.

97 t exchange, combining all expenditure modes (basic food, other food and non-food), whose parameters a

98 Brevianamide A represents a basic form of the sub-family bearing a dioxopiperazine c

99 One basic formulation (ES) contained only these ingredients

100 as been considered fundamental, arising from basic Fourier reciprocity.

101 The SPECT/CT and basic fuchsin staining revealed significant higher-densi

102 t we have an incomplete understanding of the basic function of rhizosphere microbial communities and

103 , metabolic pathway analysis can dissect the basic functional modes of subsections of core metabolism

104 -photon microscopy to compare morphology and basic functional parameters of brain populating peripher

105 ormatics scripts necessarily include similar basic functionality to read mass spectral data from stan

106 Subsequently, basic genetic and immunological tests were performed in

107 The karyotype represents the basic genetic make-up of a eukaryotic species.

108 learn random patterns and derive a number of basic geometrical and algorithmic features which suggest

109 o achieve these results, a class of Bronsted basic guanidinylated peptides, which catalyze an efficie

110 ing protein (SSBP) cofactors and DNA-binding basic helix-loop-helix (bHLH) and GATA transcription fac

111 is an MXD family transcription factor of the basic helix-loop-helix (bHLH) family.

112 CIENCY-INDUCED TRANSCRIPTION FACTOR (FIT), a basic helix-loop-helix (bHLH) transcription factor (TF),

113 Here, we showed that the basic Helix-Loop-Helix (bHLH) transcription factor Cucum

114 PHYTOCHROME INTERACTING FACTORs, a group of basic helix-loop-helix (bHLH) transcription factors.

115 erized PP2A substrates is MYC proto-oncogene basic helix-loop-helix transcription factor (MYC), whose

116 is ascribed to nuclear translocation of the basic helix-loop-helix transcription factor Transcriptio

117 The basic helix-loop-helix transcription factors collectivel

118 ME-INTERACTING FACTORS (PIFs) are a group of basic helix-loop-helix transcription factors that can ph

119 oise affects the protein dynamics of Her6, a basic helix-loop-helix transcriptional repressor.

120 , the zebrafish ortholog of human HES4, is a basic helix-loop-helix-orange transcriptional repressor

121 ranscription factors including a central MYB-basic helix-loop-helix-WD40 complex containing WEREWOLF

122 with increasing altitude is controlled by a basic/helix-loop-helix transcription factor (bHLH TF), M

123 aluable methods for directly functionalizing basic heteroarenes to form carbon-carbon bonds.

124 lic compounds (up to 178 mg/100 g) while the basic hydrolysis underestimates the phenolic concentrati

125 and bound phenols from millet in acidic and basic hydrolytic conditions were compared for the first

126 or nonspecific ionic interactions involving basic-hydrophobic (BH) sites but the mechanism of myosin

127 that cognitive effort may not share the same basic influences on avoidance behaviour as more primary

128 This work provides basic information needed for the design of tandem mass s

129 n previously forested land, in areas without basic infrastructure or access to services.

130 Despite the diversity in function, basic insight into the assembly of well-defined amphiphi

131 netics with this reporter system will enable basic investigations of virus-host interactions and faci

132 Fe-TAML entrapped in a basic ionic liquid gel exhibited consistent activity in

133 The DCI concept provides basic knowledge of the magnitude of factors affecting th

134 e insights have established a foundation for basic knowledge on how adult stem cells form, maintain,

135 The basic leucine zipper transcription factor ATF-like 3 (BA

136 ATF6 and BBF2H7 are transmembrane basic leucine zipper transcription factors and are subje

137 neurons instruct spinal networks to execute basic locomotor functions, such as gait and speed.

138 in the Dvl2 DEP domain, involving an exposed basic loop that contains the PKA site.

139 The basic machinery responsible for this regulated exocytosi

140 Basic material properties and device structures of TFTs

141 al fields, including organic fine chemistry, basic materials chemistry, pharmaceuticals, food chemist

142 th genetic studies in yeast to establish the basic mechanism of the eukaryotic cell division cycle.

143 Activity-based map formation may be the basic mechanism that establishes the matrix of topograph

144 gnized that advances in the understanding of basic mechanisms and the roles of inflammation, macrovas

145 on brain structures that are involved in the basic mechanisms of arousal(6), and we therefore hypothe

146 plications not only for our understanding of basic mechanisms of iron biology but also for the develo

147 number or function, and provide insight into basic mechanisms of neutrophil biology.

148 However, basic mechanisms of seizure initiation and propagation r

149 urrent state-of-the-art understanding of the basic mechanisms of the complex phenotype, that is, the

150 Dissecting the basic mechanisms that coordinate cell fate and tissue sh

151 s with high morbidity and mortality, yet the basic mechanisms underlying these conditions are underst

152 Experimental models of allergic disease, basic mechanisms, clinical mechanisms and allergens are

153 ete relies heavily on its arthropod host for basic metabolic functions and has developed complex inte

154 y values, including complete blood count and basic metabolic panels, were normal.

155 We also develop various extensions of our basic methods.

156 xpected mortality, estimated using the CRASH basic model.

157 rotocol takes approximately 6 h and requires basic molecular biology, mammalian cell culture and fluo

158 s between WNV and host defenses both informs basic molecular virology and promotes the development of

159 al-mesenchymal transition (EMT) represents a basic morphogenetic process of high cell plasticity unde

160 dynamic DNA nanostructures, variants on the basic motif have not been completely characterized.

161 Our results suggest that the basic motifs of cortical dynamics emerge as a consequenc

162 ixed polarization synergistically results in basic movement (backward and forward) and turning (inclu

163 corporates the varying mutation rates of the basic mutation types explains another 50% of shared vari

164 ibe an alternative "non-anhydrous, minimally basic" ("NAMB") technique that simplifies the process an

165 Sleep is a basic need.

166 ed for medications and medical supplies, and basic needs of participants were explored through interv

167 ns and to bridge the gap between research on basic neuroscience and clinical treatment.

168 onic stress and depressive-like behaviors in basic neuroscience research have been associated with im

169 Here, we review epidemiological and basic neuroscience work from the past several decades li

170 tages for aligning clinical and preclinical (basic neuroscience) studies of neuropsychiatric illness.

171 Our analysis reveals basic new features of GGN and the olfactory network surr

172 Thus, cationic complexes containing strongly basic NHC ligands and noncoordinating anions such as BAr

173 e, they tolerate many donor sites, including basic nitrogen and numerous heterocycles.

174 With three basic nitrogen atoms that can be protonated, Hoechst can

175 In this paper we study basic nonconvex 1- and 2-layer neural network models tha

176 The basic nursing curriculum should include self-care manage

177 acid and phosphatidylglycerol are the least basic of the six lipid types studied, though still more

178 th an updated review that extends beyond the basics of IFI laboratory diagnostics.

179 Most basics of the hepadnaviral life-cycle were unraveled usi

180 s are of vital importance in determining the basic optical properties of atoms, molecules and semicon

181 e all the elements are fixed, including some basic optics (3 lenses and 2 filters), a laser diode and

182 Very few PA values are available for basic organic monoradicals and none for biradicals.

183 yl-1,3,5-hexatrien-1-yl) was found to be the basic parameter affecting the final size of formed lipos

184 In addition to the basic parameters of pomegranate fruits and juices, nine

185 Species tree estimation is a basic part of biological research but can be challenging

186 with arginine-to-alanine mutations in the H4 basic patch (H4(2RA)) exhibited a significant loss of gl

187 Our findings uncover that the H4 basic patch has a regulatory function in SAGA-mediated h

188 We found that the H4 basic patch regulates H2Bub1 levels independently of int

189 Nbr adopts a HEAT-like repeat scaffold with basic patches constituting an RNA-binding surface exhibi

190 Basic pathogenic differences exist in the two forms of d

191 The SSRs are robust (with basic PCR methods and agarose gel electrophoresis), info

192 we discovered that the BARLEY B RECOMBINANT/BASIC PENTACYSTEINE transcription factors BPC1/BPC2 posi

193 Emollient (with either basic pH 8.5 or pH 5.5) was applied double-blinded twice

194 research in biology and biophysics, yet the basic physical origins of their different morphologies r

195 s for growing single crystals, and describes basic physical property measurement techniques to charac

196 They were characterized for their basic physicochemical properties, antioxidative activity

197 Surprisingly, many basic physiological principles that underlie neuronal si

198 ths, sqc163, clh, jem, and tfc covering the basic polygons and their combinations.

199 Basic polymerization reactions are the cornerstones of s

200 The basic principle of the described methodologies is also a

201 In this review, the origin, basic principles and development of electrochemical apta

202 Although the basic principles of axon guidance are well established,

203 on neurons are functionally dissociable, the basic principles of how the inputs and outputs of vCA1 a

204 In this review, we reveal the basic principles of oral bacterial delivery, from intern

205 Our findings extend our understanding of the basic principles that underpin pHLA selectivity and exem

206 This paper aims to review the basic principles to develop a strategy to follow in ultr

207 er, this paper provides a starting point and basic principles to facilitate discussions taking place

208 Although the basic process of receptor-mediated endocytosis (RME) is

209 opic cytokine, including how IL-10 regulates basic processes of neural and adipose cells and how it p

210 e a cell can be broken down into a number of basic processes.

211 eed to collect fundamental information about basic properties of the dopamine system in males and fem

212 Yet, many correctional workers lack basic protections.

213 TOR in expression and localization of myelin basic protein (Mbp) mRNA and MBP protein to the cellular

214 ter injury, characterized by impaired myelin basic protein and neurofilament NF200, the reduced thick

215 with a central role in metabolism as well as basic quality control, two processes inextricably linked

216 of some classic research in order to address basic questions about the scope and power of the group i

217 organelle was discovered 120 years ago, such basic questions as whether vesicular transport through t

218 takes slightly >3 d to complete and requires basic R skills.

219 e soil pH of the southern India sites was in basic range (8.8 +/- 0.6); whereas that of the north-eas

220 ate the innate immune response with the same basic regulatory mechanism for the human and mouse genes

221 In epidemiology, the basic reproduction number (R(0)) is used to specify the

222 To this end, we estimate the basic reproduction number [Formula: see text] and the ov

223 d using machine learning method predicts the basic reproduction number and the exponential growth rat

224 Assuming a basic reproduction number of 3.0, we constructed four sc

225 phylodynamic analysis, we estimate that the basic reproduction number of the virus was initially aro

226 d our model against previous estimates of YF basic reproductive number (R0).

227 Estimates of basic reproductive rate (R(0)) of Bsal for eastern newts

228 or the application of genome editing in both basic research and clinical practice.

229 ying intact HIV-1 proviruses is critical for basic research and clinical trials directed at HIV-1 cur

230 birch homologous group has been observed in basic research and clinical trials.

231 ctric order is of fundamental importance for basic research and device technology.

232 s intellectual foundations, we review recent basic research into the three core elements of decision

233 es, and translation of bacterial assays from basic research to routine clinical practice represents a

234 of executive and motor control concern both basic researchers and clinicians.

235 Absence of a conserved basic residue and presence of acidic residues in the ves

236 educed CAR-T cytokine production whereas the basic residue rich sequence (BRS) of CD3epsilon promoted

237 tation experiments show that both acidic and basic residues can catalyze the reaction.

238 nteractions with the substrate adenosine and basic residues in alpha5 and the alpha5-alpha6 linker th

239 Previous studies have implicated conserved basic residues in the cytosolic portions of beta- and ga

240 Furthermore, neutralization of other H4c basic residues inhibited slc13 transport function, thus

241 Trypsin, which cuts specifically after the basic residues lysine and arginine, is the predominant e

242 The addition or removal of select, conserved basic residues markedly impacts both nucleotide-dependen

243 proteases, seven of which cleave at specific basic residues within the trans-Golgi network, granules,

244 for updating model-based strategies, not for basic reward-driven action reinforcement.

245 The basic rhythmic activity that underlies stepping is gener

246 l cofactors moieties apparently contact the 'basic ridge' domain of DnaG, but not the DNA template ba

247 The basic role of this network in the human brain and how it

248 lume was determined using Schirmer's I test (Basic Schirmer's test; BST), both preoperatively and pos

249 cy, and medicine and have worked in multiple basic science departments and one clinical department.

250 nformation that is valuable for clinical and basic science investigations of cancer but extracting qu

251 It enhances interest and support of basic science research while providing opportunities for

252 Basic science research, involving solid-state chemistry

253 atter interactions with impacts ranging from basic science to technological applications.

254 essing the epidemic will require advances in basic science, development of more acceptable and effect

255 in use today, research has tended to be more basic-science oriented rather than commercially applicab

256 indings that help bridge the gap between the basic sciences and clinical application.

257 These basic scientific findings have the potential to shift th

258 Improved collaboration between urologists, basic scientists and veterinarians is warranted to furth

259 comparisons across clinical studies and for basic scientists to probe mechanisms underlying deep bra

260 a seven-question multiple-choice test about basic semiology and answered two questions evaluating th

261 phase I, 487 features were derived from the basic set of 174 features.

262 longer alpha-helices at the outer edges, and basic side grooves near the dimer interface.

263 ngle-cell level makes it a valuable tool for basic single-cell studies as well as other screening app

264 sequence processing tools to enable turnkey basic small RNA analysis.

265 Basic socio-demographic characteristics were collected a

266 This basic solution would support rapid synthesis and racemiz

267 n epigenetic modification that specifies the basic state of pluripotent stem cells and regulates the

268 Basic stomatal optimality theory posits that stomatal re

269 We use foundational basic stress biology research as a lens through which to

270 The basic structure of the products is discussed on the basi

271 For basic studies, MHS emerges as a variable stressor, which

272 nucleolytic miRNA trimming, which depends on basic surface patches.

273 nce conveyed more information distinguishing basic taste qualities and different salts than other cel

274 This basic tenet was challenged by an alternative mechanism,

275 For all neutral and basic test chemicals, the mass balance model predicted D

276 e six lipid types studied, though still more basic than alanine.

277 The basic theory for dissipative tip-sample interactions is

278 idely taken to be among the most central and basic theory of mind representations.

279 miliar with cryo-electron microscopy who get basic training in dual-beam microscopy can complete the

280 nships between these receptors to generate a basic transcriptional marker of E/I ratio.

281 ting severe depression; 2) spurred a wave of basic, translation, and clinical research; and 3) provid

282 highlights comprise the following sections: Basic & Translational Research, Cardiac Failure & Myocar

283 This hypothesis could lead to basic, translational, and clinical studies aimed at redu

284 of this reiterative framework, providing the basic, translational, and public health research communi

285 ve identified priorities directly related to basic/translational science.

286 Upon basic treatment, ortho-carborane readily undergoes debor

287 nal alkyne, whereas introduction of a weakly basic triflate counteranion results in the stereoselecti

288 error-correcting code that repairs all three basic types of DNA errors: insertions, deletions, and su

289 own about coronavirus infection, some of the basic ultrastructural cell biology that has been confuse

290 w in structured ways to dramatically advance basic understanding of biology and behavior and to lead

291 nt of non-invasive polysomnography; however, basic understanding of dog sleep patterns remains poorly

292 It requires a basic understanding of MATLAB to use the statistical spe

293 sition and physical properties of a-C films, basic understanding of the structure evolution due to ph

294 Notably, DD is the basic unit of assortativity.

295 ngs are beginning to define an engram as the basic unit of memory.

296 Whereas lipids are well known to form basic units of membrane structure and energy storage, de

297 lines at bactericidal concentrations using a basic viability assay.

298 e continuous magnitudes, which correspond to basic visual percepts, shows that both can be extracted

299 (and generally multisite modification) is a basic way of encoding substrate function and circuits/ne

300 essential and energy-intensive dimensions of basic well-being in India: food, housing and mobility.