ライフサイエンスコーパス: basis

1 has both a neurodevelopmental and a genetic basis.

2 ed for research on its evolution and genetic basis.

3 ly beginning to understand their mechanistic basis.

4 f their physicochemical nature and molecular basis.

5 should be derived on a compound-by-compound basis.

6 n, these similarities have a similar genetic basis.

7 al phenotypes of FTLD on a neuropathological basis.

8 ion of the landmarks and averaged on a slice basis.

9 ate have analyzed extremes on a site-by-site basis.

10 nced alert sirens and rocket fire on a daily basis.

11 o interpret monitoring data on a mechanistic basis.

12 1)I-omburtamab administered on an outpatient basis.

13 from different TF families on a cancer-type basis.

14 hese results constitute the first structural basis and a new model not only for the historic LIN phen

15 To characterize the genetic basis and climatic associations of natural variation in

16 Here, we show a theoretical basis and experimental support for the assertion that MT

17 ascular disease in patients, but its genetic basis and prognostic value in a population-based cohort

18 table of aggregate information on a per cell basis, as well as a summary table, is provided for furth

19 iciency and over 90% selectivity on a carbon basis at a modest electrode potential of -0.536 V vs. th

20 Yet, the physiological basis behind the restoration of fine root water uptake c

21 In particular, the molecular basis by which Ca(2+) binding affects structure and enha

22 that neurotransmitter switching provides the basis by which sustained running benefits motor skill le

23 Animals were evaluated clinically on a daily basis during a 20-day experimental period and blood samp

24 As an important basis for 'reactive' ML, we establish a first-principles

25 In summary, we provide the structural basis for a comprehensive description of ligand-receptor

26 f threshold adaptation, defining a molecular basis for a critical model feature.

27 These findings provide the basis for a mechanistic description of trans-generationa

28 with experimental results, and provides the basis for a more general description of the elasticity o

29 Our results provide the basis for a trajectory-based assessment of patients unde

30 enome for each species, which is used as the basis for a wide range of genetic analyses, including st

31 Here, we identify a genetic and biochemical basis for activation of glucosinolates to isothiocyanate

32 Our work provides a structural basis for active single- and double-ring complexes coexi

33 ur understanding of the molecular structural basis for amyloid formation by FUS and by LC domains in

34 g of the delta(13)C(TOC) record provides the basis for an astrochronological duration estimate for th

35 tion of postoperative infection is often the basis for antibiotic prescription; however, the risks of

36 The chirality of these helices offers a basis for asymmetric catalysis.

37 PCET event are hypothesized to serve as the basis for asymmetric induction in a subsequent C-N bond

38 sequence for the Spike protein, which is the basis for different vaccine candidates, matches optimize

39 We elucidate the structural basis for differential binding between NELL and Robo fam

40 These findings establish a basis for dissecting the cellular and molecular crosstal

41 A deeper understanding of the molecular basis for DNE may drive development of drugs that releas

42 es to understanding the underlying molecular basis for each of the many clinical features of DS, it a

43 To define the physical basis for EapH1's inhibition of cathepsin-G, we crystall

44 mented subdivisions (events), but the neural basis for encoding events remains unclear.

45 tivating mutations, suggesting a non-genetic basis for enhanced activity.

46 These findings provide the basis for further development of the application of deep

47 We also provide the basis for further explorations in order to better unders

48 Our study provides a basis for further investigating chrysin as a novel pharm

49 These findings should form the basis for further investigation into temporal variations

50 in an isoform-specific manner, providing the basis for further investigations elucidating the role of

51 Our study provides the basis for future investigations aiming to better define

52 zebrafish and provides the tissue mechanical basis for future studies into the role of mechanosensing

53 flexibility of the octopus arm and provide a basis for investigating motor control of the entire arm,

54 in its physical-chemical properties and is a basis for its broad successful application in pharmaceut

55 of the intact cap complex, and the molecular basis for its interaction with the filament, remains elu

56 To identify the molecular basis for lability of T3D/T1L L3S2, we screened for hype

57 ovide structural insights into the molecular basis for malfunction of disease-associated XPA missense

58 mics of the pasture ecosystem and serve as a basis for managing livestock in a more efficient way.

59 ules of interest in deep tissue, providing a basis for mapping nanomolar-scale analytes without the r

60 so affect their cellular function or be the basis for molecular probes.

61 of the GFLV-Nb23 complex, which provides the basis for molecular recognition by the Nb.

62 e on the point-of-care tests and discuss the basis for new serologic tests.

63 The evidence basis for nonoperative expectant management of traumatic

64 To better understand the molecular basis for PAR4-dependent signaling, we examined PAR4-sig

65 ore commonly applied to studying the genetic basis for phenotypic evolution as whole genomes continue

66 Well-defined pathogenic mechanisms, and the basis for phenotypic heterogeneity in this disorder, rem

67 of of concept herein points to a mechanistic basis for possible applications of pulsed magnetic field

68 e of infection-when using these results as a basis for removing precautions intended to prevent onwar

69 more complete understanding of the molecular basis for renal recovery.

70 Collectively, our data provide a mechanistic basis for reports of selective autophagy in cells lackin

71 ne the CARF domain fold, and the mechanistic basis for ring nuclease activity is discussed.

72 Our results provide a structural basis for selective CYP3A5 inhibition, along with mechan

73 agic machinery, thus providing the molecular basis for selective degradation of sizable cytosolic com

74 Together, we provide a structural basis for TbPRMT1 ENZ activation by PRO heterotetramer f

75 In this review, we examine the molecular basis for TCR activation in light of the recently determ

76 erial ribosome structures and may serve as a basis for the development of novel antibiotic compounds

77 re of mammalian ER Glu I will constitute the basis for the development of potent and selective inhibi

78 therapeutic potential of AOX1 and provide a basis for the development of prognostic markers for adva

79 poorly quantified phenomenon that forms the basis for the development of TBV.

80 ouse NaCTs and provide a plausible molecular basis for the differences based on a full-length homolog

81 Here, we explore the mechanical basis for the efferent system's capabilities at the leve

82 esults contribute to a systematic structural basis for the emerging field of quantitative R-loop biol

83 To explain the basis for the extraordinarily high recurrence rates of U

84 Altogether, these results provide a physical basis for the folding of individual chromosomes at the n

85 Our work thus offers a solid structural basis for the interpretation of a wide range of existing

86 data provide information about the molecular basis for the protein's functionality and a view of its

87 rate for each lens was plotted on a monthly basis for the same period, creating a computerized trend

88 Moreover, the neural basis for the sex differences observed in the clinical a

89 However, the mechanistic basis for the similarity of KS lesion endothelial cells

90 in complex with menin provides a structural basis for their high-affinity, covalent interactions.

91 ity of gap junctions; however, the molecular basis for these effects remains unknown.

92 phi29 ATPase (CTD) that suggest a structural basis for these functional transitions.

93 Here, we establish a structural-molecular basis for these observations.

94 The molecular basis for this change has remained elusive.

95 ted PNAG oligosaccharides, but the molecular basis for this increased activity is not known.

96 Here, we report the structural basis for this inhibition.

97 We have addressed the molecular basis for this intramolecular communication by analyzing

98 ic bioactivities of decorin as the molecular basis for tumorigenic suppression.

99 The results provide a basis for understanding global thermodynamics of multi-G

100 tion is provided here and it constitutes the basis for understanding NETs-mediated immune and hemosta

101 The model provides a formal basis for understanding the relationship between behavio

102 These findings establish robust materials basis, formation mechanism, and geological viability of

103 nal operators with respect to an orthonormal basis [Formula: see text] is not multiplicative on [Form

104 . limbatus eDNA in the bay on a near monthly basis from spring through mid-fall in 2018 and 2019.

105 overlapping, individual-specific topographic basis functions, rather than as contiguous functional ar

106 llnesses, but the elucidation of its genetic basis has proven to be a very challenging endeavor.

107 e of transcriptional return on a per nuclear basis in myofibers diminishes, which accounts for both t

108 levels of complexity constitute the genetic basis, including 1) deleterious single-nucleotide polymo

109 ether convergent adaptations share a genetic basis is consequential for understanding the evolution o

110 ractional quantum Hall effect, where the DDS basis is isomorphic to a set of degenerate Laughlin stat

111 rmed by flat surface cues, its physiological basis is not well understood.

112 ts in humans, but the underlying mechanistic basis is unclear.

113 Its molecular basis is unknown.

114 roduced in clinical practice on an empirical basis more than 100 years ago.

115 n were selected on a first-come first-served basis (n = 130; M age = 45.8, SD = 8; M BMI = 34.48 kg/m

116 sis to identify subgroups of patients on the basis of 12 clinical factors associated with cardiovascu

117 cts with IHD (2,103 patients with FH) on the basis of 28 studies, 6.7% (95% CI: 4.9% to 8.7% [1:15])

118 remature IHD (1,471 patients with FH) on the basis of 32 studies, and 7.2% (95% CI: 4.6% to 10.8% [1:

119 population (33,036 patients with FH) on the basis of 44 studies, 3.2% (95% CI: 2.2% to 4.3% [1:31])

120 holesterolemia (920 patients with FH) on the basis of 7 studies.

121 atment of patients with neuroblastoma on the basis of a combination of biomarkers that include age an

122 nexpensive ultrasonic nebulizer (USN) on the basis of a commercial room humidifier demonstrating equi

123 On the basis of a compelling data package, 20 (AM-6494) was adv

124 rim futility assessment was performed on the basis of a seven-category ordinal scale for pulmonary fu

125 6) compounds are likely synthesizable on the basis of a thermodynamic analysis of their decomposition

126 A complete understanding of the genetic basis of a trait should allow for predictive methods wit

127 Overall, our studies show the structural basis of AAV Rep's structural flexibility required to fu

128 gest that the effort to determine the neural basis of adaptive behavior could benefit from renewed ex

129 se results illustrate a circuit and synaptic basis of aggression modulation by experience, which can

130 to propagate action potentials that form the basis of all neuronal signaling.

131 proving our understanding of the biophysical basis of amyloid formation in vivo and may offer an impo

132 mpt could only be partially predicted on the basis of an existing collection of viable ADP1 single-ge

133 ritical need to better understand the neural basis of antidepressant medication (ADM) response with r

134 eolar damage, which is the histopathological basis of ARDS.

135 With growing knowledge of the genetic basis of atherosclerotic cardiovascular disease-in parti

136 crostructure at birth will reveal structural basis of behavioral emergence in typical development and

137 ity of MetMap by investigating the molecular basis of breast cancers capable of metastasizing to the

138 tion and signaling mechanism, the structural basis of CB2-selective agonists design, and the unexpect

139 These data on the molecular basis of CCD catalysis shed light on the origins of the

140 d been generated using cells selected on the basis of CD43 expression.

141 DCIS and IBC were distinguished on the basis of cell signaling and apoptosis-related ions [fatt

142 cent progress in understanding the molecular basis of cell-cell recognition, including unique phenome

143 ast cancer tissue to be characterized on the basis of cellular composition and tissue organization.

144 d have facilitated studies of the structural basis of channel gating.

145 These results pinpoint the mechanistic basis of chemotherapy-induced hyperprogression and illus

146 On the basis of chest CT findings, the patient was transferred

147 glecting the contribution of protons, on the basis of computed density estimates.

148 ng Si TL NW FET structures fabricated on the basis of cost-efficient CMOS-compatible technology.

149 ersus SAVR in older low-risk patients on the basis of current evidence supporting TAVR valve durabili

150 e-doped GaAsSb nanowires is discussed on the basis of d(0) ferromagnetism, spin ordering of the Te do

151 Although a genetic basis of depression has been well established in twin st

152 However, the basis of DGAT2's acyl-donor specificity is not known bec

153 e critical to the elucidation of the genetic basis of disease and biological function.

154 Deciphering the shared genetic basis of distinct cancers has the potential to elucidate

155 The basis of diurnal versus nocturnal behaviors is driven by

156 xide (H(2) O(2) ) with high specificity on a basis of domino reactions on the benzothiadiazole ring.

157 these inhibitors has provided the molecular basis of dual inhibitor recognition involving the cataly

158 e B-cell non-Hodgkin lymphoma in part on the basis of durable remission rates of approximately 40% in

159 To investigate the transcriptomic basis of EC specificity, we analyzed single-cell RNA seq

160 a framework for understanding the molecular basis of epigenetic maintenance mediated by Polycomb-gro

161 evidence, and updated recommendations on the basis of evidence, clinical judgement, and consideration

162 mic recruitment of neuronal ensembles on the basis of excitability and functional connectivity at the

163 On the basis of existent literature and our clinical experience

164 The basis of fluoroquinolone treatment failure for Mycoplasm

165 ver is usefully in understanding the protein-basis of GBM maintenance and repair.

166 e of detailed understanding of the molecular basis of HbF gene expression, coupled with the ability t

167 domain-swapped Fab dimers engineered on the basis of HC84.26.5D may also serve as a means of doublin

168 Consequently, the genetic basis of Hh pathway activation in adult solid tumors, su

169 However, the molecular basis of how such TRAV1-2(-) TCRs interact with MR1-anti

170 approaches to better understand the genetic basis of human brain function.

171 ically attempted to understand the molecular basis of imaging traits based on the interpretation of w

172 On the basis of immunofluorescence, infected cell types include

173 tronic devices in patients with HFrEF on the basis of individual noninvasive FFR data acutely improve

174 eria for when and how to integrate PC on the basis of individual patient needs are the initial steps

175 Here, we report the structural basis of inhibition for one target, Gsk, the inosine-gua

176 Data were analyzed on the basis of intention to treat (ITT).

177 On the basis of intention-to-treat analysis, the ICD group had

178 020) provide novel insights into the genetic basis of inter-individual differences in behavioral flex

179 ssified as having progressive disease on the basis of irRC.

180 e findings provide insight into the cellular basis of islet development.

181 into the genetic architecture and molecular basis of its evolution continues to yield novel insights

182 t enriched (2.5-fold) for inversions, on the basis of its size and duplication content.

183 his held true even for music selected on the basis of its valence and arousal levels and for traditio

184 To explore the pathogenic basis of KIF11-associated retinal vascular disease, we g

185 To clarify the molecular basis of KLF4-mediated monocytic differentiation, we per

186 lesions attributed to a benign origin on the basis of known pitfalls and information from CT.

187 hed from those that did not (n = 213) on the basis of lipid profile at baseline using a model with an

188 D-19 infection and can be used to define the basis of lung disease and test immune and antiviral-base

189 On the basis of machine learning, CEFCIG reveals unique histone

190 al aortic aneurysm (AAA) is primarily on the basis of measurement of maximal aneurysm diameter.

191 us offers opportunities to probe the genetic basis of metabolic and phenotypic variation, providing i

192 reactions are exhaustively catalogued on the basis of metal or organocatalyst.

193 proaches either identify driver genes on the basis of mutational recurrence or approximate the functi

194 ith the public sector that go on to form the basis of national vector control programs or more broadl

195 w avenue for the investigation of the neural basis of navigation behaviors and the evolution of these

196 all benefit from understanding the molecular basis of nectar-seeking.

197 facilitate novel insights into the chemical basis of neurotransmission.

198 To determine the structural basis of neutralization, we generated cryogenic electron

199 ical decision making than can be made on the basis of only an overall average treatment effect.

200 pium poppy over 200 years ago, the molecular basis of opioid action has remained the subject of inten

201 On the basis of our findings, we can conclude that the caroteno

202 On the basis of our results, we make suggestions and recommenda

203 On the basis of our systematic review and analysis, the EXTRIP

204 tumor growth and metastasis, largely on the basis of overexpression studies and the application of e

205 97 and 2018, the FDA approved opioids on the basis of pivotal trials of short or intermediate duratio

206 tial biosimilar and reference product on the basis of prespecified margins, using a study population

207 On the basis of promising results of positron emission tomograp

208 romatin-dependent protein interactome on the basis of proximity biotinylation, and applied it to dist

209 luminated another key feature of the genetic basis of psychiatric disorders: the important role and p

210 ovide a platform to elucidate the structural basis of RAF activation by RAS and to develop inhibitors

211 ironmental factors to investigate the neural basis of reinforcement-related behavior in normal adoles

212 On the basis of relative isotope ratios of protonated molecules

213 Our findings shed light on the genetic basis of resting Tpe and Tpe response to exercise and re

214 ) and major depressive disorder (MDD) on the basis of robust and distinct functional connectivity pat

215 gh, infection should not be ruled out on the basis of RT-PCR alone, and the clinical and epidemiologi

216 An understanding of the genetic basis of sex determination may lead to new methods of ma

217 ip between cardiac function and flow, on the basis of sex, by quantifying cardiac flow characteristic

218 On the basis of simulations, this approach has been argued to b

219 irst time a novel insight into the molecular basis of sinonasal mucociliary differentiation, demonstr

220 sis-like" or even "psoriasis" usually on the basis of some similarities with the human disorder.

221 nical malaria (infection and symptoms on the basis of study-specific definitions) during follow-up, a

222 ake were semiquantitatively evaluated on the basis of SUV at each time point.

223 w the current understanding of the molecular basis of telomeropathies and highlight experimental data

224 At present, the molecular basis of terminal drought tolerance of certain pearl mil

225 On the basis of the above, we suggest designing clinical trials

226 ttle progress in understanding the molecular basis of the associated loci.

227 he fertilized treatment, as predicted on the basis of the assumption that oligotrophy favors lower in

228 On the basis of the available evidence, the expert committee ma

229 e for the care of transgender persons on the basis of the best available evidence from systematic rev

230 On the basis of the combined data, the estimated risks to age 8

231 transfer could help illuminate the neuronal basis of the conscious state.

232 es involving metastable phases have been the basis of the design of numerous alloys, yet research on

233 The functional relevance and mechanistic basis of the effects of the neurotransmitter dopamine (D

234 On the basis of the International Council for Harmonisation of

235 On the basis of the largest cohort available, we observed that

236 On the basis of the mean absolute prediction error (MAE), the f

237 sed to compare prespecified schedules on the basis of the number of resistant cells where drug intera

238 On the basis of the observations reported in these studies, we

239 tes were identified as false negative on the basis of the RDTs results.

240 ion are associated with risk for CTDs on the basis of the sequence of the 22q11.2 region from 1,053 2

241 an processing, thereby providing a molecular basis of the site-specific nMPO glycosylation.

242 resonance measurements uncover the molecular basis of the so-called bridging glutamate (E205) residue

243 better understanding of the neuroanatomical basis of the stress-related feeding behaviors.

244 tect and quantify electroactive drugs on the basis of the target's redox signature.

245 f trypanothione are cytosolic, the molecular basis of the thiol redox homeostasis in the single mitoc

246 women with dental caries were divided on the basis of the treatment of dental caries, women with dent

247 th RNA "barcodelets" to identify them on the basis of the treatments they receive.

248 ydrogen-bonding network forms the structural basis of the unusual LH1 redshift.

249 ps using propensity scores calculated on the basis of their baseline clinical and demographic data.

250 On the basis of these cases, incidence of definite/probable IOI

251 riment and theory to examine the mechanistic basis of these different modes of regulation.

252 On the basis of these insights, we created trametiglue, which l

253 On the basis of these preliminary findings, temporary off-label

254 On the basis of these results, we devise a simple approach, cal

255 On the basis of these results, we propose integrated management

256 On the basis of these results, we propose the following causal

257 On the basis of these studies, we propose a dynamic equilibrium

258 ing traits, and that elucidating the genetic basis of these traits is required to assess models of ev

259 On the basis of this agreement, a possible reaction mechanism i

260 On the basis of this detection, our population synthesis analys

261 The basis of this disease heterogeneity has proved difficult

262 Understanding of the genetic basis of this disorder highlights fundamental beta-cell

263 Here, we investigated the mechanistic basis of this endogenous defense against atherosclerosis

264 Advocacy on the basis of this evidence is required to build psychosocial

265 itive effects, but the functional-anatomical basis of this heterogeneity remains poorly understood.

266 On the basis of this knowledge, we hypothesized that hepatic st

267 However, the mechanistic basis of this microbiota-brain signalling and its physio

268 On the basis of this new model we modify the non-backtracking f

269 metic (CA IX-mimic), revealed the structural basis of this particular inhibition profile and laid the

270 referentially stabilize loops, the molecular basis of this polarity remains unclear.

271 ce of virus infection, but the physiological basis of this selective IFN response is not well underst

272 we highlight how the study of the epigenetic basis of tick biology and vectorial capacity will enrich

273 every 3 weeks with sequence adjusted on the basis of timing of surgery or radiotherapy.

274 twork was able to locate brain tumors on the basis of training data that were labeled automatically f

275 ed widespread investigation into the genetic basis of transcriptional regulation.

276 al implications for understanding the neural basis of trauma-related disorders.

277 urine models that better reflect the genetic basis of trisomy 21.

278 o improve our understanding of the molecular basis of tumor development and GSL metabolism.

279 The genetic basis of variation and plasticity in these traits was in

280 On the basis of various clinical variables, patients with corre

281 nd mean and minimum ADC were measured on the basis of volumes of interest and examined with receiver-

282 g good from poor therapeutic control (on the basis of white blood cell cystine levels of <2 nmol 1/2

283 ors of stem cell biology, yet the structural basis of Wnt signaling through Fzd remains poorly unders

284 On the basis of X-ray structures of a CNS-penetrating reactivat

285 The cellular/molecular basis of ZIKV and host interactions inducing ocular and

286 On a per-patient basis, positive predictive value was 93.3% (95% confiden

287 On this basis, possible directions for further research aimed at

288 ence thousands of distinct events on a daily basis, relatively few are committed to memory.

289 ) methods using the all electron aug-cc-pVTZ basis sets.

290 These results offer a molecular basis supporting the current use of Sofosbuvir in combin

291 obviously nanoparticles offer a much richer basis than classical homogeneous and heterogeneous catal

292 These results provide a rational basis to address the heretofore unknown mechanism of mag

293 This finding provides knowledge basis to enhance maize hybrids grain yield.

294 these overall findings suggest a physiologic basis to prefer therapeutic surgical weakening of the me

295 el macromolecular structures have provided a basis to understand biological function.

296 ty of highdimensional data have provided the basis to validate the existence of CCs.

297 liids, monocots, and eudicots; the molecular basis underlying floral scent biosynthesis; and winter f

298 ers, yet little is known about the molecular basis underlying inhibitory control.

299 ism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not completely u

300 Arousal was modulated on a trial-by-trial basis using fear-conditioned (CS(+)) stimuli.