ライフサイエンスコーパス: be aberrantly activated

1 ro-inflammatory gene program of the organism is aberrantly activated.

2 nhibitor of the Wnt signaling pathway, which is aberrantly activated across a wide range of human tum

3 Developmental signals are aberrantly activated and stem cell functions are dis

4 tivators of Transcription (JAK/STAT) pathway is aberrantly activated and contributes to ADPKD pathoge

5 rase for branched-chain amino acids (BCAAs), is aberrantly activated and functionally required for ch

6 ion factor nuclear factor-kappaB (NF-kappaB) is aberrantly activated and that inhibition of NF-kappaB

7 Here we demonstrate that PAK is aberrantly activated and translocated from cytosol to

8 T family of proteins, the ways in which they are aberrantly activated, and the molecular mechanisms b

9 ion, supporting the hypothesis that CaN-NFAT are aberrantly activated by Abeta and that CaN-NFAT acti

10 osphatidylinositol 3-kinase (PI3K) signaling is aberrantly activated by a mutant thyroid hormone beta

11 to the cell that occurs when these pathways are aberrantly activated either in the absence of stress

12 The Ras proteins are aberrantly activated in a wide range of human cancer

13 Fms-like tyrosine kinase 3 (FLT3) signaling are aberrantly activated in acute myelogenous leukemia (

14 -like growth factor-1 (IGF-1) signaling axes are aberrantly activated in both primary PCa and bone me

15 opic analyses to demonstrate that mast cells are aberrantly activated in human and murine osteoarthri

16 Rheb2 small GTPases and their effector mTOR are aberrantly activated in human cancer and are attract

17 ndicate that the RANK and NF-kappaB pathways are aberrantly activated in luminal progenitor cells res

18 ed that STAT3 and ras-ERK signaling pathways are aberrantly activated in Sle1ab B lymphocytes, consis

19 e and adaptive immune responses, is known to be aberrantly activated in a wide variety of cancers.

20 igenic axis, and suggest that Crtc genes may be aberrantly activated in a wider range of common adult

21 rocesses during metazoan development and can be aberrantly activated in cancer.

22 l proliferation and survival, often found to be aberrantly activated in cancer.

23 elopment and tissue regeneration, thought to be aberrantly activated in epithelial-derived cancer and

24 linositol-3 kinase (PI3K)/Akt pathway, which is aberrantly activated in >50% of carcinomas, inhibits

25 The hedgehog (Hh) signaling pathway is aberrantly activated in a majority of basal cell carc

26 The Notch pathway is aberrantly activated in a wide range of cancers, incl

27 We found that HOTTIP is aberrantly activated in acute myeloid leukemia (AML)

28 Hedgehog pathway signalling is aberrantly activated in around 95% of tumours.

29 e formation, suggesting that the Wnt pathway is aberrantly activated in breast cancer mammospheres.

30 mesenchymal transition (EMT), a process that is aberrantly activated in cancer and facilitates metast

31 l growth, proliferation, and metabolism that is aberrantly activated in cancers and certain cancer-as

32 rm cells and repressed in somatic cells, but is aberrantly activated in cancers.

33 B-cell receptor (BCR) signaling is aberrantly activated in chronic lymphocytic leukemia

34 e same pathway as Tsc genes, the TOR pathway is aberrantly activated in ciliary mutants, resembling t

35 Here we show that promoter 1 is aberrantly activated in colon cancers because it is a

36 ntestinal stem cell (ISC) proliferation, and is aberrantly activated in colorectal cancer.

37 Here we show that STAT6 is aberrantly activated in cyst-lining cells in PKD mous

38 is is strongly stimulated during fasting and is aberrantly activated in diabetes mellitus.

39 beta-catenin signaling is aberrantly activated in different gastrointestinal ca

40 B-catenin signaling is aberrantly activated in different gastrointestinal ca

41 d endoplasmic reticulum (ER) stress response is aberrantly activated in Emu-TCL1 mouse and human CLL.

42 A host effector that is aberrantly activated in gastric cancer precursor lesi

43 the insulin-like growth factor (IGF) pathway is aberrantly activated in HCC by IGF2 overexpression.

44 onstrate that the IGF2/IGF-1R/IRS1 signaling is aberrantly activated in Herceptin-resistant breast ca

45 proliferation, survival, and metabolism, and is aberrantly activated in human cancer.

46 ion 3 (STAT3) is a transcription factor that is aberrantly activated in many cancer cells.

47 r of the proto-oncoprotein beta-catenin that is aberrantly activated in many cancers.

48 ucial role in several cellular processes and is aberrantly activated in many cancers.

49 g effectors, thus controlling a pathway that is aberrantly activated in medulloblastoma.

50 The hedgehog signaling pathway is aberrantly activated in most BCC tumors providing an

51 is essential for intestinal homeostasis and is aberrantly activated in most colorectal cancers (CRC)

52 TET1ALT is aberrantly activated in multiple cancer types includi

53 Accordingly, Ras is aberrantly activated in NF1-deficient tumors; however

54 ow that the anaplastic lymphoma kinase (ALK) is aberrantly activated in ovarian cancer.

55 We show that classical NF-kappaB is aberrantly activated in Ras- or Raf-transformed RLEs,

56 We found that Wnt signalling is aberrantly activated in regeneration-deficient tissue

57 mTORC1 is aberrantly activated in renal cell carcinoma (RCC) an

58 ese pathways, Sonic Hedgehog (SHH) signaling is aberrantly activated in several human cancer entities

59 The transcription factor STAT3 is aberrantly activated in several tumors, where its con

60 f the lymphoid enhancer factor-1 (LEF1) gene is aberrantly activated in sporadic colon cancer, wherea

61 The Wnt/beta-catenin signaling pathway is aberrantly activated in the majority of colorectal ca

62 The Wnt/B-catenin signaling pathway is aberrantly activated in the majority of colorectal ca

63 y confined to germ cells of adult testes but is aberrantly activated in the vast majority of neoplast

64 ovide in vivo evidence that the mTOR pathway is aberrantly activated in TSC renal pathology and that

65 scade, a pathway regulating cell growth that is aberrantly activated in tuberous sclerosis complex (T

66 ed that the Hedgehog (Hh) signalling pathway is aberrantly activated in vulval squamous cell carcinom

67 TNF-producing CD4(+) T cells in AIH seem to be aberrantly activated Th1 cells.