ライフサイエンスコーパス: be aberrantly expressed

1 small number of splicing factors observed to be aberrantly expressed.

2 iate genes, including extra-embryonic genes, are aberrantly expressed.

3 or lymphoid enhancer-binding factor 1 (LEF1) is aberrantly expressed across all subtypes and stages o

4 nude mice of human cancer cells in which Akt is aberrantly expressed/activated but not of those cance

5 imprinted genes (Mest, Peg3, Snrpn and Meg3) are aberrantly expressed although allele specific DNA me

6 TK) family of receptor tyrosine kinases that are aberrantly expressed and have been implicated as the

7 phenomenon, a small set of genes appears to be aberrantly expressed and may affect critical developm

8 imary ovarian tumor tissues and found ALK to be aberrantly expressed and phosphorylated in 4 tumors.

9 ated protein kinase (MAPK) signaling pathway is aberrantly expressed and maintains transformed cell g

10 a direct transcriptional target of EVI1 that is aberrantly expressed and selectively required in both

11 sent family of protein phosphatases (EYA1-4) is aberrantly expressed and tumor-promoting across many

12 ium, the normally silent paternal H19 allele was aberrantly expressed and undermethylated.

13 enesis associated factor (SPAF) was found to be aberrantly expressed at the malignant conversion stag

14 We found that RSPO3 is aberrantly expressed at high levels in approximately

15 These data show that FLT3 RNA and protein are aberrantly expressed by AML and ALL cells in that CD

16 ICAM-1 is aberrantly expressed by astrocytes in CNS pathologies

17 y discovered co-stimulatory immune receptor, is aberrantly expressed by human AML cells, and can be u

18 ests that 30% of genes have the potential to be aberrantly expressed during tumorigenesis.

19 We found that 142 genes were aberrantly expressed (>2.0-fold) with 64 genes up-r

20 related human ether-a-go-go (hEAG1) channel are aberrantly expressed in a large proportion of human

21 blished that low concentrations of myoglobin are aberrantly expressed in a significant proportion of

22 otubule-associated protein like 4-ALK, which are aberrantly expressed in a subset of T-cell anaplasti

23 (CTAs) are normally expressed in testis but are aberrantly expressed in a variety of cancers with va

24 d against two human cell cycle proteins that are aberrantly expressed in breast cancer: p34cdc2 kinas

25 ch modulate the function of full-length p53, are aberrantly expressed in breast cancers.

26 post-transcriptional regulation of mRNAs and are aberrantly expressed in cancer with important roles

27 D1, D2, and D3) promote G1-S progression and are aberrantly expressed in cancer.

28 evidence indicates that many homeobox genes are aberrantly expressed in cancers, and that their dere

29 rray analysis showed that up to 10% of genes are aberrantly expressed in demethylated fibroblasts.

30 Many bromodomain-containing proteins are aberrantly expressed in diseases, as best studied in

31 several other genes implicated in psoriasis are aberrantly expressed in high-grade, comedo DCIS.

32 omprehensive understanding of all genes that are aberrantly expressed in human cancer.

33 mily of immunogenic testicular antigens that are aberrantly expressed in human cancers in a lineage-n

34 d estrogen-related receptor alpha (ERRalpha) are aberrantly expressed in human colon cell lines and t

35 ophil elastase (HNE) and proteinase 3 (PR3), are aberrantly expressed in human myeloid leukemias.

36 tified thus far, we demonstrated that miRNAs are aberrantly expressed in hypertrophic mouse hearts.

37 Key signaling developmental pathways are aberrantly expressed in IPF.

38 uppressor PTEN inhibits AKT2 signaling; both are aberrantly expressed in liver tumors.

39 atidic acid (LPA) and its receptors LPA(1-3) are aberrantly expressed in many types of human cancer.

40 Germline genes that are aberrantly expressed in nongermline cancer cells hav

41 om cancer patients to identify proteins that are aberrantly expressed in ovarian tissue.

42 Nox isoforms are aberrantly expressed in several cells derived from h

43 in the testis in the normal human adult but are aberrantly expressed in several types of cancers.

44 r of apoptosis (Tweak) and its receptor Fn14 are aberrantly expressed in spinal astrocytes and skelet

45 hat a significant fraction of periodic genes are aberrantly expressed in the cyclin mutant.

46 ession and show that a large number of genes are aberrantly expressed in the Fur mutant specifically

47 demonstrated for the first time that miRNAs are aberrantly expressed in the vascular walls after bal

48 Importantly, these GC-regulated genes are aberrantly expressed in TNBC patients and are associ

49 utologous serum antibodies to molecules that are aberrantly expressed in tumors represent potential b

50 dies have revealed that thousands of lncRNAs are aberrantly expressed in various cancer types, and so

51 oarray analysis, we demonstrated that miRNAs are aberrantly expressed in vascular smooth muscle cells

52 Many Hsp90 clients have been reported to be aberrantly expressed in a number of cancers.

53 itor of cell apoptosis and has been found to be aberrantly expressed in a wide range of human disease

54 In contrast, GRP/GRPR can be aberrantly expressed in colon cancer where they are a

55 Similarly, p14(ARF) did not appear to be aberrantly expressed in ex vivo ATLL cells nor in any

56 ding endothelial cell markers that appear to be aberrantly expressed in highly aggressive melanoma ce

57 B7 coregulatory ligands can be aberrantly expressed in human disease.

58 ly expressed only in male germ cells but may be aberrantly expressed in melanomas and other tumors.

59 Many are reported to be aberrantly expressed in various cancers, including he

60 ovel miRNAs and showing that these genes may be aberrantly expressed in various human tumors.

61 receptor tyrosine kinases, was identified as being aberrantly expressed in a significant proportion o

62 We observe HDAC11 is aberrantly expressed in 25 cancer types and positivel

63 in the maintenance of ES cell self-renewal, is aberrantly expressed in 47.7% of primary human endome

64 The oncogenic transcription factor TAL1/SCL is aberrantly expressed in 60% of cases of human T cell

65 Here, we show that uPA is aberrantly expressed in a high percentage of human pr

66 amma signaling and antigen presentation that is aberrantly expressed in a small subset of primary tum

67 The HOX11/TLX1 homeobox gene is aberrantly expressed in a subset of T-cell acute lymp

68 GRP78 serves as a master UPR regulator that is aberrantly expressed in a variety of cancers, includi

69 In summary, B7-H3 is aberrantly expressed in all prostate cancers and repr

70 in 1-C-terminal subunit (MUC1-C) oncoprotein is aberrantly expressed in AML blasts and stem cells; ho

71 The MUC1 oncoprotein is aberrantly expressed in AML cells; however, there has

72 The ETS transcription factor ERG is aberrantly expressed in approximately 50% of prostate

73 or primary recessive autosomal microcephaly, is aberrantly expressed in autism-like disorders and hum

74 cAMP-dependent serine/threonine kinase that is aberrantly expressed in autosomal dominant polycystic

75 The Met receptor tyrosine kinase is aberrantly expressed in breast cancer and predicts po

76 RKIP also inhibits syndecan-2 (SDC2), which is aberrantly expressed in breast cancer, via downregula

77 Survivin is a putative oncogene that is aberrantly expressed in cancer cells.

78 gastrin-releasing peptide receptor (hGRP-R) is aberrantly expressed in cancers of the colon, lung an

79 The HERV-K envelope glycoprotein (Env) is aberrantly expressed in cancers, autoimmune disorders

80 n D1 regulates G1 cell-cycle progression and is aberrantly expressed in carcinogenesis.

81 an MMACHC, a downstream target of HCFC1 that is aberrantly expressed in cblX.

82 s a direct E2F target and, as a consequence, is aberrantly expressed in cells with Rb pathway defects

83 Like NOVA2, UNC5B- 8 is aberrantly expressed in colon cancer vasculature wher

84 servations that PPARdelta, similar to COX-2, is aberrantly expressed in colorectal tumors and that en

85 t the active phosphorylated form of MAPK/ERK is aberrantly expressed in cultured and primary HD cells

86 ication of a stem cell regulatory gene which is aberrantly expressed in glioma and associated with pa

87 MUC1 is aberrantly expressed in greater than 90% of all breas

88 tially expressed antigen of melanoma (PRAME) is aberrantly expressed in hematologic malignancies and

89 e normal expression is highly restricted but is aberrantly expressed in hematologic malignancies incl

90 on site-1), located on chromosome band 3q26, is aberrantly expressed in human acute myeloid leukemia

91 ne receptor for coagulation factor VII/VIIa, is aberrantly expressed in human cancers.

92 hway component BCL9 is a novel oncogene that is aberrantly expressed in human multiple myeloma as wel

93 ctor-kappaB (NF-kappaB) RelA/p65 pathway and is aberrantly expressed in human multiple myeloma cells.

94 SALL4 is aberrantly expressed in human myelodysplastic syndrom

95 glein-2 (Dsg2) is a desmosomal cadherin that is aberrantly expressed in human skin carcinomas.

96 e nantais (RON), a tyrosine kinase receptor, is aberrantly expressed in human tumors and promotes can

97 CXCR4 is aberrantly expressed in immune-mediated diseases and

98 strain a neural gene expression program that is aberrantly expressed in intellectual disability.

99 staglandin synthase cyclooxygenase-2 (COX-2) is aberrantly expressed in intestinal tumors resulting f

100 r TGF-beta-induced profibrotic responses and is aberrantly expressed in lesional tissue in systemic s

101 s and growth differentiation factors (GDFs), is aberrantly expressed in lower-risk MDSs and PMF.

102 pecific cell types in ovary and placenta but is aberrantly expressed in lymphomas, neuroblastomas, re

103 The MYC oncogene is aberrantly expressed in many human cancers and regula

104 scriptional coactivator of beta-catenin that is aberrantly expressed in many human cancers but is of

105 As such, MCPH1 is aberrantly expressed in many malignancies, including

106 in the pathogenesis of pancreatic cancer and is aberrantly expressed in many other epithelial carcino

107 N-Myc is a transcription factor that is aberrantly expressed in many tumor types and is often

108 tor kappa B (NF-kappaB) subunit (NF-kappaB2) is aberrantly expressed in many tumour types and has bee

109 Histone deacetylase 11 (HDAC11) is aberrantly expressed in many types of cancer, and suc

110 Since it is aberrantly expressed in metastatic tumors, which have

111 ) is an oncogenic transmembrane protein that is aberrantly expressed in MM cell lines and primary tum

112 The protein Vav1 is aberrantly expressed in more than half of pancreatic

113 opmental- and tissue-specific expression and is aberrantly expressed in most metastatic tumors.

114 in 1 C-terminal subunit (MUC1-C) oncoprotein is aberrantly expressed in most MM cells, and targeting

115 The MUC1-C oncoprotein is aberrantly expressed in most multiple myeloma cells.

116 on factor nuclear factor erythroid 2 (NF-E2) is aberrantly expressed in MPN patients.

117 during antigen-driven lymphocyte responses, is aberrantly expressed in mucosa-associated lymphoid ti

118 pes, we observed Wilms tumor only when Lin28 is aberrantly expressed in multiple derivatives of the i

119 1, is a widely recognized tumor antigen that is aberrantly expressed in myeloid and lymphoid leukemia

120 is as yet unknown, but significantly, CD155 is aberrantly expressed in neuroectodermal tumors.

121 Additionally, Mer is aberrantly expressed in numerous other malignancies s

122 Mer is aberrantly expressed in numerous other malignancies s

123 The oncogenic transcription factor TAL1/SCL is aberrantly expressed in over 40% of cases of human T

124 search has shown that the mucin protein MUC4 is aberrantly expressed in pancreatic adenocarcinoma cel

125 MUC4 is a transmembrane mucin, which is aberrantly expressed in pancreatic adenocarcinoma wit

126 It is aberrantly expressed in pancreatic adenocarcinoma, wh

127 Although MUC13, a transmembrane mucin, is aberrantly expressed in pancreatic ductal adenocarcin

128 It is aberrantly expressed in pancreatic tumors and tumor c

129 located in SCZ-associated genetic locus and is aberrantly expressed in patients with SCZ.

130 , we show that the zinc finger protein ZBED2 is aberrantly expressed in PDA and alters tumor cell ide

131 Cyclooxygenase-2 (COX-2) is aberrantly expressed in premalignant adenomatous poly

132 th factor (VEGF), a key angiogenic molecule, is aberrantly expressed in several diseases including as

133 Tissue factor (TF) is aberrantly expressed in solid cancers and is thought

134 in that is normally limited to mucous glands is aberrantly expressed in surface mucous cells of H. py

135 HOX11 encodes a homeodomain protein that is aberrantly expressed in T-cell acute lymphoblastic le

136 s been stimulated by reports showing that it is aberrantly expressed in the cytoplasm and/or nucleus

137 -grade endometrioid adenocarcinomas, and (c) is aberrantly expressed in the tumor epithelial cells of

138 Importantly, BRCC36 is aberrantly expressed in the vast majority of breast t

139 y selective expression in normal tissues, it is aberrantly expressed in tumor cell lines from several

140 target of rapamycin (PI3K/AKT-mTOR) pathway] is aberrantly expressed in uterine fibroids.

141 (K(+)) channel of large conductance (BK(Ca)) is aberrantly expressed in various breast cancer (BC) su

142 Mucin 1 (MUC1) is aberrantly expressed in various cancers and implicate

143 ditionally, we determined that cytochrome bd was aberrantly expressed in the DeltaresDE cmp backgroun

144 lncRNA transcripts and 1109 mRNA transcripts were aberrantly expressed in 6- and 20-week-old db/db he

145 approximately one-quarter of all genes that were aberrantly expressed in a breast cancer cell line u

146 sults showed that TET2, EZH2, MAD2 and CDC20 were aberrantly expressed in AML patients.

147 der normal conditions, transcribed ventrally were aberrantly expressed in dorsal and lateral neural t

148 ntly, many genes implicated in Wnt signaling were aberrantly expressed in Fancc(-/-) B cells.

149 Fifty-six ucRNAs were aberrantly expressed in HepG2 cells compared with n

150 y expressed in infarcted areas and 33 miRNAs were aberrantly expressed in the border areas.

151 paradoxical concanavalin A (con A) staining were aberrantly expressed in the surface mucous cells of

152 in both groups, whereas the CRABP2 and FABP5 were aberrantly expressed in the tumor cells of the seba

153 SOX11 is aberrantly expressed not only in mantle cell lymphoma

154 Both of these truncated glycans are aberrantly expressed on the MUC1 glycoprotein in a s

155 vily glycosylated transmembrane protein that is aberrantly expressed on greater than 90% of human bre

156 Epithelial cell MUC1 is aberrantly expressed on human epithelial adenocarcino

157 th critical endoplasmic reticulum functions, is aberrantly expressed on the surface of cancer cells,

158 Delta-like ligand 3 (DLL3) is aberrantly expressed on the surface of small-cell lun

159 and the transmembrane subunit ASGP-2, which is aberrantly expressed on the surfaces of a variety of

160 omarkers for pathologies in which miR levels are aberrantly expressed, such as cancer.

161 dly, SOX9, a hair follicle growth regulator, was aberrantly expressed throughout the IFE of the mutan

162 The transmembrane mucin, MUC4, is aberrantly expressed with a high incidence in human p