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2 ikingly, these electroretinographic deficits are abrogated in a dose-dependent manner by systemic adm
3 antigen specificity, its therapeutic effect is abrogated in a mouse model requiring pertussis toxin.
5 glia following TNF-alpha stimulation, which was abrogated in a dose-dependent manner by acetylcholin
10 LMP1-mediated NF-kappaB and AP-1 activation were abrogated in a dose-dependent manner, with a concom
11 ed Akt phosphorylation or cell proliferation was abrogated in A7r5 cells overexpressing a dominant-ne
12 2-mediated resistance to SN-38 and topotecan was abrogated in ABCG2-transfected HEK-293 cells treated
15 mAChR-induced inhibition of proliferation is abrogated in all cell lines when Galpha(q/11) signali
16 ractions between beta-catenin and E-cadherin were abrogated in all three immortalized MMECLs and the
23 zation and the ensuing MAP kinase activation was abrogated in B-lymphocytes and fibroblasts derived f
24 demonstrate that the protective effect of E2 is abrogated in B6.129-Esr1(tm1Unc) mice (Esr1-/-) but n
25 xpression in response to T. gondii infection was abrogated in B6 IFNAR-/- mice, which lack a function
26 a caspase 3-defective cell line (MCF-7) and was abrogated in Bak-sensitive tumors after administrati
30 r, the inhibitory effects of epsilon subunit are abrogated in both purified F(1) and membranous F(o)F
33 ATP hydrolysis and drug transport activities were abrogated in both E556Q and E1201Q mutant Pgps, [al
34 , we show that activation of caspase-3 by UV is abrogated in BRCA1-mutated SNU251 and HCC1937 cells b
38 Accordingly, the inotropic effects of Hsp20 were abrogated in cardiomyocytes expressing nonphosphory
39 + macrophage infiltration into the heart and was abrogated in CCR2(-/)(-) mice, demonstrating target
43 ony-stimulating factor-secreting tumor cells was abrogated in CD1d- and J alpha 281-deficient mice, r
47 inally, we demonstrate that these structures are abrogated in cells derived from incontinentia pigmen
49 cytokine responses by a pathogen product can be abrogated in cells derived from TLR4 knockout, but no
51 of the downstream transcription factor, CSL, is abrogated in cells deficient in presenilins or treate
52 f MMP-9 in response to NGF, as this response is abrogated in cells expressing a mutant TrkA receptor
56 tion of movement by the FKBP52 PPIase domain is abrogated in cells treated with colcemid to eliminate
57 n the host we asked whether the AID response was abrogated in cells deficient in the interferon pathw
58 n-induced inhibition of centrosome splitting was abrogated in cells expressing Nek2 mutated in the PP
66 at serine 133 and CREB DNA binding activity were abrogated in cells treated with inhibitors of eithe
68 t cells, execution of PUMA-induced apoptosis is abrogated, in company with decreases in caspase activ
69 This enhancement in TSHR-/- and TSHR+/- mice is abrogated in compound TSHR-/-/TNFalpha-/- and TSHR+/-
71 ection against I/R-induced intestinal injury is abrogated in conventionally derived Nod2(-/-) mice an
79 lpha, IL-1 beta, MCP-1, IL-8, and MIP-1 beta was abrogated in Egr-1 small inhibitory RNA-transfected
81 ly, the atheroprotective action of tamoxifen is abrogated in ERalpha(-/-)LDL-r(-/-) mice and in LDL-r
82 ast majority of E2-dependent gene regulation was abrogated in ERalpha-AF2(0), whereas in C451A-ERalph
85 ranasal infection with ST3, but its efficacy was abrogated in FcgammaR (F common gamma receptor)-defi
92 ve effects of dietary tryptophan restriction are abrogated in germ-free mice, but are independent of
93 ed NF-kappaB activation in enteric glia that was abrogated in glia from TLR4 knockout mice and by kno
94 ia and subsequent Parkin-dependent mitophagy is abrogated in glucose-free medium or in the presence o
96 this model, we have shown that cell widening is abrogated in growth conditions that promote higher su
99 , and ApoB in response to cytokine treatment were abrogated in HepG2 cells with dramatically reduced
100 MPK) dependent since all the effects studied were abrogated in HFD apelin-treated mice with muscle-sp
104 fects of radiotherapy and STING agonists can be abrogated in humans by a translational strategy invol
106 growth inhibition observed in LPS-B16 tumors was abrogated in IFNAR1-deficient mice lacking a functio
107 nding Notch target gene activator RBP-Jkappa was abrogated in Ik(-/-) double-positive thymocytes.
111 RXDX-106 was observed in wild-type mice and was abrogated in immunodeficient mice, suggesting that t
112 n Deltaarg or control intracellular survival was abrogated in iNOS-deficient macrophages, suggesting
113 ng hepatic steatosis and glucose intolerance-were abrogated in Insp3r1 (also known as Itpr1)-knockout
115 contrast, CAF16, a potential ligand of CCR4, was abrogated in its binding to the LRR by mutations in
116 n-E production and dermatitis by delta-toxin was abrogated in Kit(W-sh/W-sh) mast-cell-deficient mice
119 ortantly, the membrane translocation of Vav3 was abrogated in Lck, ZAP-70, LAT, and SLP-76-deficient
120 be not cell type specific as its expression was abrogated in leukemic, skin, kidney, lung, and pancr
121 oth insulin receptor and Akt phosphorylation were abrogated in liver, but not in adipose tissue or in
124 triggered by poly(I:C), dsRNA, and viral RNA was abrogated in macrophages lacking cryopyrin or the ad
127 regulation of mTORC1 signaling by DNA damage is abrogated in many cancer cells, thus mTORC1 signaling
130 xpression and prostaglandin E2 release could be abrogated in metastatic breast cancer cells by inhibi
131 n volume fraction in MHCsTNF/c-kit(+/-) mice was abrogated in MHCsTNF/c-kit(-/-) mice, and that the l
132 very that NAS neuroprotective effects in EAE are abrogated in mice lacking IDO1 expression, we invest
136 han in CD4-replete mice, and this difference was abrogated in mice depleted of neutrophils before UVB
137 of the endothelial barrier, and this effect was abrogated in mice exposed to PDGF-BB neutralizing an
138 responsiveness of the endogenous RANKL gene was abrogated in mice from which we deleted this conserv
139 2 detoxication and antioxidant enzymes, and was abrogated in mice lacking the nrf2 gene, which regul
141 betes protection conferred by the NOR allele was abrogated in mice treated with exogenous type 1 IFN-
142 ation, tubular damage, and renal dysfunction were abrogated in mice deficient in MyD88; NLRP3, ASC, a
143 ronal glutathione content, and these effects were abrogated in mice genetically deficient in either N
147 found that TNF-induced NF-kappaB activation was abrogated in MKK4 gene-deleted cells, as determined
148 , colony forming ability and leukemogenicity are abrogated in MLL-AF9 containing either the CGBP or M
149 ATM-proficient cells, whereas this response is abrogated in MMR-deficient cells and attenuated in AT
151 rome c-mediated apoptotic pathway because it was abrogated in mouse embryonic fibroblasts with knocko
153 el in which multi-isoform TGF-beta signaling is abrogated in multiple leukocyte lineages while leavin
156 roduction by macrophages and dendritic cells is abrogated in MyD88 and TLR4, but not TLR2, knockout,
157 tive advantage conferred by the mutant Csf3r was abrogated in myeloid progenitors lacking both Stat5A
160 rejection of Clr-b(-/-) hematopoietic cells was abrogated in Nkrp1b-deficient recipients, which lack
161 induced IL-1beta production in serum, which was abrogated in Nlrp3-null mice but was unaffected in P
163 costimulatory molecules, and Ag degradation were abrogated in NOTAM DCs in response to FcgammaR liga
165 sponse and suppression of the iNOS induction was abrogated in nrf2(-/-) and keap1(-/-) mouse embryoni
167 h transcription across the Zac1/Plagl1 locus is abrogated in oocytes, resulting in failure of DNA met
171 cted mutagenesis study, antioxidant activity was abrogated in p53R2 mutants Y331F, Y285F, Y49F, and Y
172 The interaction between BRCA1 and BRCA2 is abrogated in PALB2-deficient Fanconi anemia cells and
179 mediated by killer cytotoxic lymphocytes: it is abrogated in perforin-deficient mice or mice depleted
183 01), the protective effects of second window were abrogated in pigs with CD resulting in an infarct s
184 As a consequence, dendritic cell trafficking is abrogated in polysialyltransferase-deficient mice, ma
186 th this, Akt-induced mammary differentiation was abrogated in Prl(-/-), Prlr(-/-), and Stat5(-/-) mic
187 ivity, and how their antagonist activity may be abrogated in prostate cancer that progresses after an
189 ocation: the latter response to all agonists was abrogated in R1B cells or by pretreatment of Mv1Lu c
190 chological stress and whether such responses are abrogated in RA patients taking TNFalpha antagonists
192 erved during the early phases of disease and were abrogated in recombination-activating gene 1-defici
196 changes in ER-alpha expression and activity were abrogated in response to estradiol by an arginine t
197 7, caspase-1 activation and IL-1beta release were abrogated in response to signals that activate NLRP
199 esponses following isoproterenol stimulation were abrogated in RyR1-S2844A mice in which the serine i
203 The dephosphorylation of phospho-Lyn Tyr507 was abrogated in Shp2-deficient cells transfected with t
205 n of several of the biogenic amine receptors is abrogated in specific cell types in Lhx gene mutants,
211 tivity of the cHS4 element was also found to be abrogated in studies using bone marrow from Parp1-nul
219 of normal thymocyte differentiation, but it is abrogated in TCR-transgenic mice, which prematurely e
220 tion and nondeletion components of tolerance were abrogated in TCR transgenic H-Y-specific lpr (Fas-d
227 ility of these fibrils to increase infection are abrogated in the presence of various polyanionic com
229 ddition, the cystine addiction phenotype can be abrogated in the cystine-addictive cells by miR-200c,
235 hibited the overall currents, an effect that is abrogated in the almt12(-/-) and (2) reduced the curr
236 P1 complex-mediated inhibition of telomerase is abrogated in the context of the POT1 H266L mutation,
239 ted 185 amino acid protein, whose expression is abrogated in the mu allele which contains an insertio
240 In H. polygyrus infection, ST2 detection is abrogated in the peritoneal cavity and lung, consiste
243 2H) exhibits a growth-inhibitory effect that is abrogated in the presence of glutamate dehydrogenase
244 Destabilization of p53 by aurora kinase A is abrogated in the presence of mutant Mdm2 that is unab
246 ry between control and TRPM5 knockdown cells was abrogated in the absence of extracellular Ca(2+) and
247 and the antiapoptotic effect of GSK-3beta-DN was abrogated in the absence of myeloid cell leukemia-1.
253 ene than in the wild type and that apoptosis was abrogated in the Delta yca1 strain, whereas wild typ
256 pithelial cells and to induce IL-8 synthesis was abrogated in the presence of a specific NK-1 recepto
257 manner because the protective effect of IL-6 was abrogated in the presence of a STAT3 inhibitor and u
258 n of some of NRF2's antioxidant target genes was abrogated in the presence of ACA11 overexpression.
259 creting INS-1E cells, respectively, and this was abrogated in the presence of an irisin-neutralizing
260 ause priming of macrophages by anti-CD40 mAb was abrogated in the presence of anti-IFN-gamma mAb, as
261 ITC-induced activation of p38 protein kinase was abrogated in the presence of its specific inhibitor
262 led to enhanced PDGFRalpha expression, which was abrogated in the presence of nuclear factor kappaB (
264 iation of both fibroblasts and preadipocytes was abrogated in the presence of TGF-beta; this effect w
265 of CGRP to stimulate cAMP and IL-8 synthesis was abrogated in the presence of the CGRP receptor antag
267 ArcABC), histidine (HutI), and serine (SdhA) was abrogated in the rgg mutant strain, which synthesize
270 d and observed that the effects of RELMalpha were abrogated in the absence of adaptive immunity.
271 found that the effects of the fibrate drugs were abrogated in the absence of retinoid X receptor-alp
272 -regulated differences in protein expression were abrogated in the mutant, indicating that the mening
273 ts in endothelial function in eNOS(-/-) mice were abrogated in the presence of 25 mm KCl, implicating
276 hat the fumarate-stimulating ULBP2/5 pathway is abrogated in these cells as an immune-evasive strateg
277 her, leptin action on euglycemia restoration was abrogated in these mice, which was associated with r
281 CpG-ODN-induced intraocular inflammation was abrogated in TLR9(-/-) and macrophage-depleted mice.
282 the elevated corticosterone response to SEA was abrogated in TNF-/- mice and was shown to be cortico
284 mycin-induced down-regulation of peroxisomes was abrogated in transforming growth factor beta (TGF-be
285 lopment of anti-beta-cell surface antibodies was abrogated in treated mice compared with controls.
288 directly correlated with p63 expression and is abrogated in tumor cells that overexpress endogenous
290 relative protection afforded by PR8 priming was abrogated in tumor necrosis factor-deficient (TNF(-/
292 urthermore, the upregulation of PG0893 (hcp) was abrogated in V2807 exposed to nitrosative stress.
293 tection of needle-challenged vaccinated mice was abrogated in vector-initiated cutaneous leishmaniasi
294 tion and peripheral tolerance, both of which are abrogated in vitro by mediators of T cell help.
295 M3 inhibitory effect on EGFR tyrosine kinase was abrogated in vitro by coincubation with glycan havin
298 fection with ST3 and found that its efficacy was abrogated in Wt mice depleted of macrophages intrana
299 nhanced barrier integrity and cell migration were abrogated in ZO-1 knockdown cells, indicating ZO-1