ライフサイエンスコーパス: be active against

1 epitope, our results suggest that Ig-2D1 may be active against 06HA only in the absence of glycosylat

2 dene]carbonimidic dihydrazide hydrochloride) were active against 24 clinical MRSA and MSSA isolates.

3 In the PhenoSense assay, T-1249 was active against 636 different HIV-1 Env-pseudotyped v

4 famethoxazole (TMP-SMX) and fluoroquinolones were active against 94% and 88% of isolates, respectivel

5 ecies, compounds that bind to the new target are active against a broad spectrum of bacterial species

6 Prediction of compounds that are active against a desired biological target is a comm

7 c acid carbamoyl methyl amides (PACMAs) that are active against a panel of human ovarian cancer cell

8 Anti-PD-L1 antibodies are active against a variety of cancers, and combined an

9 Agents targeting topoisomerases are active against a wide range of human tumors.

10 y active neutralizing antibodies (NAbs) that are active against a wide variety of circulating strains

11 The ideal antibiotic should be active against a broad spectrum of pathogenic organis

12 ementarity to identify compounds expected to be active against a given target.

13 molecules as an antiviral therapy that could be active against a wide range of influenza viruses and

14 te broadly neutralizing antibody (bnAb) that is active against a broad range of HIV-1 primary isolate

15 can generate a potent triamino scaffold that is active against a panel of hard-to-kill epithelial can

16 actericidal lipoglycopeptide antibiotic that is active against a range of clinically relevant gram-po

17 Rebeccamycin analog (NSC 655649) is active against a variety of both solid and nonsolid t

18 SVS-1 is active against a variety of cancer cell lines such as

19 Irinotecan is active against a variety of malignancies; however, se

20 LipA is active against a wide range of fatty acid esters of p

21 Since STI571 is active against A-MuLV-transformed cells in vitro, we

22 In vivo, FdUMP[10] was active against a syngeneic AML model with a survival

23 All three drugs were active against a panel of seasonal H3N2 and laborat

24 These compounds were active against a transformed human colon cancer cel

25 acetylated substrates in vitro, only CjCE2C was active against acetylated mannan in Physcomitrella.

26 , are directly active against Ad3, and IP-10 is active against Ad5.

27 Thalidomide is active against advanced myeloma.

28 Iseganan, an antimicrobial peptide, is active against aerobic and anaerobic gram-positive an

29 The 4-nitroimidazole PA-824 is active against aerobic and anaerobic Mycobacterium tu

30 tool for risk assessment showed coumarin to be active against Aliivibrio fischeri bacteria down to 1

31 embers of the miR-34 family of miRNAs, which are active against all three viruses as well as the clos

32 Sofosbuvir (SOF) is active against all hepatitis C virus (HCV) genotypes,

33 st activity against xanthine than uracil and is active against all xanthine-containing DNA (C/X, T/X,

34 Itraconazole was active against all Candida spp. (96% of MICs were <

35 Voriconazole was active against all Candida spp. except C. glabrata (

36 In addition, MEDI3902 was active against all tested isolates.

37 LyeTxI and LyeTxI/betaCD were active against all strains tested at concentrations

38 producers, and (iii). in vitro, carbapenems are active against AmpC-producing strains of K. pneumoni

39 We also confirmed that Bald's eyesalve is active against an important eye pathogen, Neisseria g

40 associated with exposure to antibiotics that are active against anaerobes.

41 ings suggest that GBP2 and GBP5 have already been active against ancient viral pathogens as they supp

42 terminal, glycine-rich attacin-analog region was active against any of the bacterial strains studied,

43 aryl-2-(3-indolyl)acetohydroxamic acids that are active against apoptosis- and multidrug-resistant ca

44 The echinocandins and triazoles were active against Aspergillus spp. (MIC90/minimum effe

45 pecific chimeric antigen receptor (CD19.CAR) are active against B-cell malignancies, but it is unknow

46 Crenolanib was active against Ba/F3 cells harboring FLT3-ITD and se

47 , anhydrodinemasone BC, and nor-dinemasone B are active against bacteria, including Legionella pneumo

48 AcpP PPMO is active against Bcc infections in vitro and in vivo.

49 -blocking activity in rodent malaria models, are active against blood-stage field isolates of the maj

50 The natural product cladosporin is active against blood- and liver-stage Plasmodium falc

51 reased efficacy compared with bortezomib and was active against bortezomib-resistant MM cell lines an

52 (F98Y) S. aureus DHFR and found that several are active against both enzymes and specifically that th

53 s with unprecedented chemical scaffolds that are active against both Gram-positive and Gram-negative

54 They are active against both parasite and mammalian CPs, desp

55 Therefore, new anti-TB agents, which are active against both the replicating form of Mtb (R-T

56 Of these agents, delafloxacin is unique in being active against both gram-positive and gram-negativ

57 KAF156 is a novel antimalarial drug that is active against both liver- and blood- stage Plasmodiu

58 l candidate 35b (vaniprevir, MK-7009), which is active against both the genotype 1 and genotype 2 NS3

59 LeAOS was active against both 13S-hydroperoxy-9(Z),11(E),15(Z)

60 Recombinant OPCL1 was active against both OPDA and OPC-8:0, as well as med

61 Chloroplast-produced BglC was active against both pure cellobiose and against toba

62 te specificity studies suggested that AGPAT6 was active against both saturated and unsaturated long-c

63 lysis showed that the recombinant leukotoxin was active against bovine polymorphonuclear leukocytes a

64 roduced for treatment of metastatic melanoma are active against brain metastases and offer new opport

65 All agents except for the echinocandins were active against C. neoformans, and the triazoles wer

66 he antiproliferative activity, all compounds were active against Caco-2 cell line, being the ones wit

67 conventional peptidic inhibitors of hTS that are active against cancer cells and do not result in the

68 y a fraction of expanded gamma9delta2T cells was active against cancer cells and that activity of the

69 Analogue 17 was active against carbapenem-resistant and polymyxin-re

70 en to identify small-molecule compounds that are active against CCAs.

71 Laulimalide was active against cell lines resistant to paclitaxel or

72 e VLY and ILY, which are human specific, INY is active against cells from a broad range of species.

73 veral human cancer cell lines, cyclostreptin was active against cells resistant to paclitaxel and epo

74 supernatants of chitin-grown strain 2-40 and was active against chitin and glycol chitin.

75 Flavopiridol is active against chronic lymphocytic leukemia (CLL) cel

76 Compounds from this series were active against clinical Mtb strains, while no cross

77 le of eliciting neutralizing antibodies that are active against clinically relevant HIV-1 strains.

78 New generation azoles that are active against clinically relevant, drug-resistant f

79 Two bisabolane derivatives were active against colon cancer cell lines and may be i

80 high concentrations in pulmonary tissues and is active against common pathogens that cause community-

81 discovered, and the most promising compounds were active against COX-1 in intact ovarian carcinoma ce

82 enic acid and ergosterol endoperoxide, which were active against Cryptococcus neoformans and methicil

83 Thus, cotreatment with LBH589 and AMN107 is active against cultured or primary IM-resistant CML c

84 Furthermore, treatment with LBH589 was active against cultured primary Ph(-) ALL cells, inc

85 gests that these compounds have potential to be active against CWD in vivo.

86 We found that roscovitine is active against cysts originating from different parts

87 re encapsidated in HIV-1 and SIV virions and were active against Deltavif SIV(mac) and SIV(agm).

88 the parasite's replicative blood stages and is active against developing gametocytes, the forms resp

89 The isolated lipase was active against diolein, but not triolein.

90 z-423 is a novel immunomodulatory agent that is active against disease even in the context of defecti

91 ly-induced antiviral gene expression program is active against disparate human arthropod-borne viruse

92 velopment of new antituberculosis drugs that are active against dormant or persister populations of M

93 ng the first 28 days of therapy and rifampin was active against dormant bacilli after the establishme

94 iferation, we hypothesized that the polymers were active against dormant cancer cells.

95 We show here that AbsB is active against double-stranded RNA transcripts derive

96 xhibited excellent bactericidal activity and was active against drug-sensitive and resistant Mtb.

97 of several interferon-stimulated genes that are active against EBV.

98 ous indirect photoinactivation mechanism may be active against Ent. faecalis, it is not for the sewag

99 virus (HSV1 and HSV2), and another compound was active against Epstein-Barr virus (EBV).

100 Several panitides were shown to be active against Escherichia coli and cytotoxic to HeLa

101 Antibacterial assays confirmed that gallin was active against Escherichia coli, but no additional a

102 We conclude the following: (a) 4-HPR was active against ESFT cell lines in vitro at concentra

103 sults also demonstrate that these mechanisms are active against established tumor as well as developi

104 spofungin resistant C. albicans strains, and was active against established C. albicans biofilms in v

105 cysteine proteases out of which 18 compounds were active against falcipain-2 and falcipain-3.

106 and only approximately 1% of the inhibitors are active against five or more kinases.

107 ovel TKI, demonstrates type I properties and is active against FLT3 containing ITD and/or D835- or F6

108 The preparation was active against fluorogenic substrates specific for c

109 C(27) 3beta-HSD cDNA encodes an enzyme that is active against four 7alpha-hydroxylated sterols, indi

110 We investigated whether resveratrol is active against fresh acute myeloid leukemia (AML) cel

111 S-1 plus cisplatin is active against gastric cancer and has a favorable tox

112 a series of N-lipidated peptide dimers that are active against Gram-negative bacteria, including car

113 t(M)) tetracycline-resistance mechanisms and are active against Gram-positive and Gram-negative organ

114 Previous studies have shown that ADEPs are active against Gram-positive bacteria (e.g., MRSA, V

115 nhibitors, with several derivatives found to be active against Gram-positive and mycobacterial pathog

116 The antibiotic, paenibacterin, is active against Gram-negative and Gram-positive bacter

117 Fosmidomycin, a potent DXR inhibitor, is active against Gram-negative bacteria.

118 Results show that the hydrogel surface is active against Gram-positive (Staphylococcus epidermi

119 Here we demonstrate that promysalin is active against Gram-positive and Gram-negative bacter

120 The lantibiotic NAI-107 is active against Gram-positive bacteria including vanco

121 in, a lipoglycopeptide antibiotic agent that is active against gram-positive pathogens, has a long pl

122 Pa-MAP 1.9 was active against Gram-negative planktonic bacteria and

123 ial activities showed that the date extracts were active against Gram (+) and Gram (-) bacteria, show

124 The obtained compounds were active against Gram-positive bacteria, including mu

125 The compounds were active against Gram-positive pathogens and revealed

126 cin, linezolid, tigecycline, and minocycline were active against >90% of VISA isolates, while >90% of

127 These new peptides were active against H3N2 and H1N1 strains of IAV.

128 Furthermore, several antiretroviral agents are active against HBV infection, including lamivudine,

129 ast, the 2-aza analogue of sangivamycin (30) was active against HCMV and HSV-1 but this apparent acti

130 ogues with hydrogen-bond-accepting character were active against HCMV (e.g., 3-formyl-2,5,6-trichloro

131 In vitro studies demonstrate that 1 is active against HCT-15, AGS, PC-3, and LNCaP tumor cel

132 The lead compound 7h which is active against HCT116 and SW620 with IC(50) of 1.3 an

133 Preoperative trastuzumab and paclitaxel is active against HER2 overexpressing early-stage breast

134 a larger family of cytidine deaminases that are active against HIV-1 and other retroviruses.

135 CN) and triciribine-5'-monophosphate (TCN-P) are active against HIV-1 at submicromolar concentrations

136 FDA-approved HIV-1 protease inhibitors (PI) are active against HIV-2.

137 to the design of new inhibitors predicted to be active against HIV protease.

138 ino-5-arylthiobenzonitriles (1) was found to be active against HIV-1.

139 of acyclic nucleoside monophosphate prodrugs being active against HIV-1.

140 N-MCD4T is active against HIV-1 and HIV-2 in CEM, MT-2, and MT-4

141 that the cationic polypeptide fraction of SP is active against HIV-1, and that semenogelin-derived pe

142 The APIs released in vitro and in vivo were active against HIV-1ADA-M, HSV-2, and HPV16 PsV in

143 re are currently no specific antivirals that are active against HPVs.

144 ty testing then resulted in three leads that were active against HsFPPS with IC50 values in the range

145 RC-2 was active against HSV-1 KOS in cultures and showed prot

146 family of antiviral cytidine deaminases that are active against human immunodeficiency virus, simian

147 esence of the active-site residue Ser-529 to be active against human PGHS-1; the S529A mutant is resi

148 's cytotoxicity screen, compounds 11a and 12 were active against human cancer cell lines derived from

149 The compound is active against important Gram-negative pathogens both

150 TAS-103 is a novel antineoplastic agent that is active against in vivo tumor models.

151 is a need to find new chemical entities that are active against infections of T. brucei.

152 nsights as to how targeted dsRNAs in general are active against insects.

153 The tricyclic nucleoside 12, was active against its target virus, human immunodeficie

154 We conclude that EXEL-0862 is active against KIT activation loop mutants and is a p

155 All of the hydroxylated analogues were active against L1210 cells with 96-h IC(50) values

156 Tenofovir disoproxil fumarate (TDF) is active against lamivudine-resistant hepatitis B virus

157 previous work predicted that Tdp1p would not be active against lesions involving Top2p.

158 sensitive cells, compounds 1-6 were found to be active against leukemia K562 cells with IC50 in the n

159 tomegalovirus and along with the Z-isomer 5a was active against leukemia L1210 and solid tumors in vi

160 Notably, the dasatinib/PD184352 regimen was active against leukemic cells exhibiting various for

161 ty, we identified purine-type compounds that were active against lung small cell lung cancer (NSCLC).

162 Methotrexate (MTX) is active against lymphomas, but transport or polyglutam

163 inhibitor of LepB (MD3; a beta-aminoketone) was active against M. tuberculosis, exhibiting growth in

164 se activity; these acyldepsipeptides (ADEPs) were active against M. tuberculosis.

165 ry approval of a new macrolide/ketolide that is active against macrolide-resistant pathogenic bacteri

166 some strain-specific anti-HIV cytokines, CAF is active against many different virus isolates, includi

167 re potent against BCR-ABL than imatinib, and is active against many imatinib-resistant BCR-ABL mutant

168 Minocycline intravenous is active against many MDR strains of Acinetobacter, and

169 In vitro, the enzyme is active against many serotypes of S. pneumoniae, indep

170 beta-ketoiminato complexes has been shown to be active against MCF-7 (human breast carcinoma), HT-29

171 ne repertoire of T cells and antibodies that are active against melanoma, with recent glimpses of the

172 e phosphatidylinositol phosphate kinase that is active against membrane-bound substrates.

173 High dose interleukin-2 (IL-2) is active against metastatic melanoma and renal cell car

174 hat spirohexenolide A, a spirotetronate that is active against methicillin-resistant Staphylococcus a

175 tance with marketed antibacterial agents and is active against methicillin-resistant staphylococcus a

176 Both toxins are active against mice when administered intracerebrove

177 Aplidin is active against MM cells in the presence of proliferat

178 to inhibit IspC in a number of organisms and is active against most gram-negative bacteria but not gr

179 ng the myristoyl-binding pocket of BCR-ABL1, is active against most single mutants but ineffective ag

180 We show that engineered monomeric YoeB is active against mRNAs bound to both the small and larg

181 antibiotic with a unique mode of action that is active against MRSA, but its clinical use is restrict

182 Although vancomycin is active against MRSA, it does not effectively kill int

183 ophenyl)methylene]carbonimidic dihydrazide), was active against MRSA and VRE with MIC's of 8.1 and 4.

184 losis, are nontoxic to human cell lines, and are active against multidrug-resistant M. tuberculosis s

185 (2) developing and evaluating regimens that are active against multidrug-resistant organisms.

186 strategies should focus on antibiotics that are active against multidrug-resistant tuberculosis and

187 GaMF1 is bactericidal and is active against multidrug- as well as bedaquiline-resi

188 a novel member of the fluorocycline family, is active against multidrug-resistant bacteria including

189 e/tazobactam, a novel antimicrobial therapy, is active against multidrug-resistant Pseudomonas aerugi

190 ent interaction with SIRPalpha on phagocytes are active against multiple cancer types including T-cel

191 ries of c-Met small molecule inhibitors that are active against multiple mutants previously identifie

192 onstrate that four of these crystal proteins are active against multiple nematode species and that ea

193 ifficulties in creating a vaccine that would be active against multiple clades of HIV.

194 is prediction, and suggest that levosimendan is active against multiple cancers, notably lymphoma, th

195 ce from disseminated candidiasis and that it is active against multiple virulent strains of C. albica

196 de (chlorosulfaquinoxaline, CQS, NSC 339004) is active against murine and human solid tumors.

197 ntify and design inhibitors that will likely be active against mutants found in different cancers.

198 it primary FLT3-mutant AML blast growth, and is active against mutations that confer resistance to cl

199 MIC) = 4 ug/mL], while the blue benzoquinone is active against Mycobacterium tuberculosis (MIC = 4 ug

200 (PZA) to ammonia and pyrazinoic acid, which is active against Mycobacterium tuberculosis.

201 (e.g., thalidomide and lenalidomide), which are active against myeloma, also block the activity of b

202 h are structurally distinct from crizotinib, are active against NB cells expressing ALK(F1174L).

203 Topotecan is active against neuroblastoma when it is administered

204 after cyclophosphamide is a combination that is active against newly diagnosed RMS, with an acceptabl

205 bitory concentrations (MIC) against R-TB and were active against NRP-TB in the low micromolar range,

206 , followed by immune checkpoint blockade may be active against NSCLC.

207 ot an acid sphingomyelinase but unexpectedly is active against nucleotide diphosphate and triphosphat

208 In contrast 29 and 31 were active against one or both of these viruses but act

209 ) while 5-nitroimidazoles like metronidazole are active against only anaerobic Mtb.

210 ic cyanobacterium Hassallia sp. and found to be active against opportunistic human pathogenic fungi.

211 ertain E. faecalis clinical isolates, and it is active against other E. faecalis strains.

212 We also found that auranofin is active against other Gram-positive bacteria, includin

213 everal previously identified RGS4 inhibitors were active against other RGS members, such as RGS14, wi

214 ive against C. neoformans, and the triazoles were active against other yeasts (MIC90, 2 mug/ml).

215 Levofloxacin, gentamicin, and tetracycline were active against oxacillin-susceptible staphylococci

216 ary results indicated that compounds 3 and 6 are active against P. berghei, prolonged the life span o

217 r, our findings indicate that 4 human sPLA2s are active against P. falciparum in vitro and pave the w

218 Single-dose phage therapy was active against P. aeruginosa EE and highly synergist

219 teryl linoleate and cholesteryl arachidonate were active against P. aeruginosa at physiological conce

220 zylamine 12a and alpha-methylbenzylamine 12g were active against P. falciparum with IC50 values in th

221 These compounds also were active against pathogenic Staphylococcus aureus .

222 Lefamulin, a pleuromutilin antibiotic, is active against pathogens commonly causing community-a

223 d once daily either orally or intravenously, is active against pathogens that commonly cause such inf

224 l drugs for Clostridium difficile infections were active against pathogens included in the WHO priori

225 Importantly, CpdA was active against patient-derived plasma cells and both

226 t of sarcoma but rarely for medulloblastoma, was active against PDXs representing Group 3 medulloblas

227 epper line over-expressing functional CaCel1 was active against pepper matrix glycans in vitro, and s

228 LyeTxI and LyeTxI/betaCD are active against periodontopathic bacteria, showing ra

229 r of DUSP1, encoding a dual phosphatase that is active against phospho-ERK.

230 ophobic and positively charged clusters that are active against plant and human pathogens.

231 enzene-1,3-diamine) (dihydrochloride), which is active against Plasmodium berghei in vivo (oral ID(50

232 The N-acyl-2-amino-4-chlorophenyl sulfides were active against Plasmodium falciparum.

233 ibitors (PIs) recently have been reported to be active against Pneumocystis carinii in cell culture.

234 ithromycin in combination with sulphonamides is active against Pneumocystis carinii pneumonia (PCP) i

235 Finally, we demonstrated that the prodrugs are active against primary chronic lymphocytic leukemia

236 ere we show that the PI3K inhibitor GDC-0941 is active against primary T-ALLs from wild-type and Kras

237 Complexes 1-8 are active against promastigotes of Leishmania major and

238 Many inhibitors have been identified that are active against purified viral-encoded integrase prot

239 To determine whether this regimen is active against quiescent G(0)/G(1) MM cells, cells we

240 Maraviroc, a CCR5 antagonist, is active against R5 but not X4 or dual- or mixed-tropic

241 otecan administered on a protracted schedule is active against recurrent FHWT.

242 zylguanidine ((131)I-MIBG) has been shown to be active against refractory neuroblastoma.

243 Neratinib plus capecitabine is active against refractory, HER2-positive breast cance

244 e-3-carboxamide derivatives, which proved to be active against replicating Mycobacterium tuberculosis

245 ere is currently a dearth of new agents that are active against resistant bacterial species.

246 py, and the development of novel agents that are active against resistant forms of target proteins cr

247 es with modified side chains, such as AQ-13, are active against resistant parasites, we compared AQ-1

248 cessitates the discovery of antibiotics that are active against resistant pathogens.

249 Two IgA MAbs (33G2 and 35H6) were active against ricin's lectin subunit (RTB), and tw

250 Maribavir is active against RR CMV strains.

251 Maribavir >=400 mg twice daily was active against RR CMV infections in transplant recip

252 ue to its nuclear localization because SENP1 is active against sentrinized RanGAP1 in vitro.

253 novel propargyl-linked DHFR inhibitors that are active against several trimethoprim-resistant enzyme

254 Our data indicate that PD180970 is active against several Bcr-Abl mutations that are res

255 as been exploited as a biocontrol agent that is active against several insect pests.

256 72) inhibits 1,3-beta-d-glucan synthesis and is active against several medically important fungi but

257 Azithromycin is a macrolide antibiotic that is active against several periodontal pathogens.

258 (IL-12) is an immunomodulatory cytokine that is active against several viruses.

259 We found that M2-S31N inhibitors were active against several influenza A viruses that are

260 atives showed rapid bactericidal killing and were active against several multidrug-resistant (MDR) Gr

261 APOBEC3F was found to be active against SIV and sensitive to SIV(mac) Vif.

262 SJG-136 was active against small (150 mg) and large (250-400 mg)

263 otherapeutic agents has been identified that are active against solid tumors.

264 oreover, both phenanthrene-based derivatives were active against stage IV/V gametocytes of P. falcipa

265 The most potent leads are active against Staphylococcus aureus [minimal inhibi

266 Compound 1a was active against Staphylococcus aureus in mice (iv) an

267 ROAD-1 was active against Staphylococcus aureus, Escherichia co

268 orary naturally infected cattle in Botswana) were active against strain M375 in an in vitro growth in

269 licin M-like bacteriocin, pectocin M2, which is active against strains of Pectobacterium spp.

270 eriophages and the first virus documented to be active against streptococci.

271 receptors on the surface of mammalian cells, is active against T. gondii tachyzoites (50% effective c

272 otency of PC-1505 was sustained, and PC-1505 was active against T-20-resistant ("DIV") virus with a G

273 l-cell fusion and live virus replication and was active against T20 resistant strains.

274 ine/adenosine analogues to remain intact and be active against the parasite, they need to either be r

275 Importantly, compound 12 was found to be active against the tested XDR-TB strains and orally a

276 Since the prompt institution of therapy that is active against the causative pathogen is one of the m

277 eftaroline is a new antibacterial agent that is active against the major bacterial pathogens found in

278 It is active against the persistent, non-replicating mycoba

279 t/Km) is the main function of enzyme when it is active against the specific substrate.

280 e specific helicase inhibitors (compound 17) was active against the replicon and inhibited the helica

281 Compound 1 was active against the tested five human cancer cells, w

282 The compound was active against the three major schistosome species i

283 Quinolones were active against the bacterial enteropathogens in the

284 Tetrahydro-beta-carboline-3-carboxylic acids were active against the hydroxylation of 2'-deoxyguanosi

285 rug therapies and to discover new drugs that are active against these organisms.

286 nstructural protein 5A (NS5A) inhibitor that is active against these genotypes, improves efficacy and

287 TFO-5a was active against this target and inactive against the

288 All these compounds were active against three strains of gametocytes with di

289 CB2 was active against tOspB of strain B31, but not against

290 Most of the samples were active against Trypanosoma b.

291 acid, in addition to inhibiting osteoclasts, is active against tumor cells and suggest that zoledroni

292 RETRA is active against tumor cells expressing a variety of p5

293 The polyamide was active against two enzalutamide-resistant xenografts

294 d glycopeptides with hydrophobic side chains are active against vancomycin-resistant enterococci and

295 ne derivatives, three compounds are found to be active against vancomycin and methicillin-resistant S

296 Pronucleotide 7a was active against varicella zoster virus with EC(50) 6.

297 Cytosine and thymine Z-isomers 11c and 11d were active against varicella zoster virus (VZV) with EC

298 AM7 is active against wild-type c-Met as well as several mut

299 ide reverse-transcriptase inhibitor (NNRTI), is active against wild-type Human Immunodeficiency Virus

300 nt screens, the most potent compound 9 (1C8) was active against wild-type HIV-1IIIB (subtype B, X4-tr