ライフサイエンスコーパス: be alleviated by

1 onic lethality induced by Brca1 mutation can be alleviated by 53BP1 deletion.

2 romosomal aberrations in p97-deficient cells are alleviated by a concomitant downregulation of DDB2 o

3 d BLA synaptic plasticity after juvenile HFD are alleviated by a glucocorticoid receptor antagonist.

4 uce more hydrogen peroxide, (ii) the effects are alleviated by a radical scavenger and (iii) the glut

5 hair loss and skin lesions; both behaviours are alleviated by a selective serotonin reuptake inhibit

6 ating the essentiality of these genes cannot be alleviated by a coinfecting microbe.

7 t; some detrimental effects of migration may be alleviated by a greater abundance of forage.

8 tritional environment in utero, which cannot be alleviated by a nutritionally balanced post-weaning d

9 investigates whether these two problems can be alleviated by a sequential niche technique without lo

10 that the G(1) phase requirement for cAMP can be alleviated by a single protein, cyclin D1.

11 rgy supply and demand imbalance, which might be alleviated by a variety of interventions, including p

12 The TMG requirement for PCH2 splicing is alleviated by a CACUAAC to UACUAAC change restoring a

13 The extent to which this burden is alleviated by a hearing device is a major, unresolved

14 e growth defect of a reg1 reg2 double mutant is alleviated by a loss-of-function mutation in the SNF1

15 while NEP decreases due to delayed snowmelt were alleviated by a relief of water stress.

16 hich the lethal effects of ideR inactivation were alleviated by a second-site suppressor mutation and

17 ound-mediated inhibition on feeding behavior is alleviated by acids.

18 c CO(2) induces an HCO(3)(-) deficiency that is alleviated by acquisition of CA or Ci uptake, thereby

19 ntroduction of the missing component of MMR, is alleviated by activated Akt.

20 3K) in HEK293 cells elicits G(2) arrest that is alleviated by activated Akt.

21 cytoskeleton and that these constraints can be alleviated by activity-dependent degradation of Tiam1

22 inhibition of AtPI4Kalpha1 by PtdIns4P could be alleviated by adding recombinant AtPI4Kalpha1 PH doma

23 abilities with thermally drawn nanowires can be alleviated by adding tungsten carbide nanoparticles t

24 of MICA/B by a reversible mechanism that can be alleviated by addition of d-mannose; this does not, h

25 PS1 resulting from down-regulation of PEN-2 is alleviated by additional siRNA down-regulation of APH

26 fur resulted in copper hypersensitivity that was alleviated by additional deletion of entC, preventin

27 Disease symptoms can be alleviated by administering high doses of rIL-22-Fc,

28 played the "short-sleep phenotype," and this was alleviated by administering 20E at the adult stage.

29 Implantation failure was alleviated by administration of bone marrow-derived

30 sgenesis in eyes lacking both CYP1B1 and TYR was alleviated by administration of the tyrosinase produ

31 richia coli even at low-glycine levels which is alleviated by alanine supplementation.

32 ular Ca(2+) homeostasis, the effect of which was alleviated by ALDH2.

33 Here we show that this problem is alleviated by allowing some cross-modal matching befo

34 effect is in part mediated centrally and can be alleviated by altering motor cortex function.

35 lted in chronic intestinal inflammation that was alleviated by antibiotic treatment and entirely aver

36 e brain and depressive phenotypes, which can be alleviated by antidepressant drugs or by overexpressi

37 eral trigger of [PSI(+) formation, which can be alleviated by antioxidant defenses.

38 ed as neurotoxic molecules whose effects can be alleviated by antioxidant enzymes.

39 Decrease in TIMP1 expression is alleviated by antioxidant administration, small inter

40 dered neurotoxic molecules whose effects can be alleviated by antioxidants.

41 Auditory hallucinations in schizophrenia are alleviated by antipsychotic agents that inhibit D2 d

42 Although psychosis symptoms can be alleviated by antipsychotics, cognitive symptoms rema

43 nd malnutrition in the poorest countries may be alleviated by applying genomics or other tools of bio

44 es previously observed in the monomers could be alleviated by assembly or maturation.

45 idly develop a cholinergic syndrome that can be alleviated by atropine.

46 everity of neutropenia-related infection can be alleviated by augmenting phosphatidylinositol (3,4,5)

47 on fork impairs its helicase activity, which is alleviated by binding of the single-stranded DNA bind

48 induce nociceptive behaviors in mice, which is alleviated by blocking TNFa.

49 led to growth suppression and apoptosis that was alleviated by both the somatic and constitutional mu

50 omegaly caused by myeloerythroid hyperplasia were alleviated by Btk deficiency in lyn-/- mice.

51 cant cell death in the suprabasal layers and was alleviated by caspase inhibition.

52 reby decreasing TAMs infiltration, which can be alleviated by CCL2 addition.

53 ed mouse, marrow aplasia caused by TBI could be alleviated by cell therapy with human bone marrow mes

54 This obstruction is alleviated by chromatin relaxation via ATM-dependent

55 sponses and cell death than WT, all of which are alleviated by co-incubation with oleate via TAG chan

56 These phenotypes are alleviated by co-treatment with either of two differ

57 This inhibition was alleviated by co-expression of proteins that bind th

58 The toxic effect of Txe was alleviated by co-expression of the antitoxin protein

59 FrmRE64H (which gains an RcnR metal ligand) is alleviated by cobalt and Zn(II).

60 However, this toxicity could be alleviated by coexpression of mep72 with the adjacent

61 a dose-dependent inhibition of passage which was alleviated by coexpression of the putative negative

62 g to the severe kidney shortage, which might be alleviated by compensating living kidney donors.

63 The membrane-depolarizing activity is alleviated by coproduction of the membrane-bound TsaI

64 is also impaired; this anaemia can generally be alleviated by correction of the underlying disease pr

65 st with urothelial barrier dysfunction could be alleviated by cutting urinary K(+) levels.

66 iated by the RNA silencing pathway but which is alleviated by cycloheximide.

67 control reduced viability following UVB that was alleviated by cycloheximide (CHX), indicating that t

68 The inhibition of Hg(II) methylation was alleviated by decreasing the free Zn' concentration

69 e ESCRT pathway on particle production could be alleviated by deleting a portion of the NC domain tog

70 This repression can be alleviated by deletion of the TRD from MeCP2 or by in

71 lopmental block in GRB2-deficient thymocytes is alleviated by deletion or inhibition of SHP1 and is e

72 In contrast, rd3 degeneration was alleviated by deletion of GCAPs.

73 in curli production in nagA or nagC mutants was alleviated by deletion of the GlcNAc transporter gen

74 Repression was alleviated by deletion of the NMTS, which did not af

75 compromised cell viability, and this effect was alleviated by depletion of autophagosome machinery p

76 ir defect observed in cells expressing S473A was alleviated by depletion of HP1-beta, suggesting that

77 anxiety-like behaviors in the zero maze that were alleviated by diazepam.

78 esting clinically in growth failure that can be alleviated by dietary restriction of carbohydrates.

79 ygen interference on flunitrazepam detection was alleviated by dissolving an effervescent tablet of v

80 The myosin II defect of corA(-) mutant is alleviated by dominant-negative p21-activated kinase

81 sfunctional eating behavior of VAChTcKO mice was alleviated by donepezil and by l-DOPA, confirming an

82 nt with this, longevity defects in pgs1Delta were alleviated by down-regulation of the high osmolarit

83 operties of misfolded rod opsin in cells can be alleviated by drug treatments targeted against a rang

84 We show that cleavage inhibition can be alleviated by either artificially melting the protosp

85 kely caused by the transport scheme, and can be alleviated by employing a less diffusive Lagrangian s

86 t, in principle, this form of diabetes could be alleviated by enhancing the targeting of MIDY mutants

87 the class III PI3K inhibitor 3-methyladenine was alleviated by essential amino acid supplementation.

88 -strand resection, but this inhibition could be alleviated by excess MRN.

89 ngly, ABA-induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a fu

90 This LR primordium induction was alleviated by exogenous PI4P, suggesting that PI4KII

91 ions in zebrafish larvae, and this phenotype was alleviated by exogenously supplied biliverdin.

92 stractibility exhibited in adolescence could be alleviated by experience with the association task as

93 xication and relatively high cytopathic dose were alleviated by exposing TcsL to acid pH, resulting i

94 However, this repression could be alleviated by exposure to Tc or IPTG, which inhibited

95 (tau and neurofilament medium), effects that were alleviated by expressing phosphomimetic, but not ph

96 This requirement for divK was alleviated by expression of a constitutively active

97 alities in autophagy markers p62 and LC3B-II were alleviated by ezetimibe and pranlukast.

98 has a strong growth requirement for Mn that is alleviated by Fe supplementation.

99 obility in tail suspension and this response was alleviated by fluoxetine, reboxetine, and bupropion.

100 the frmRA operator-promoter, and repression is alleviated by formaldehyde but not manganese, iron, c

101 Disease was alleviated by genetic deletion of T-bet.

102 The efficacy of Q203 and related derivatives was alleviated by glycerol supplementation.

103 otational abnormality in 6-OHDA treated rats was alleviated by GPI-1046.

104 The resultant rewarming injury could be alleviated by gradual rewarming using controlled oxyg

105 diment to the translation of mgtL, which can be alleviated by high [Mg(2+)] exerted on component(s) o

106 menopause can lead to epidermal changes that are alleviated by hormone replacement therapy (HRT).

107 When stress is alleviated by housing at thermoneutral ambient temper

108 We found that As-induced yield losses were alleviated by Husk amendment, partially alleviated

109 in LTalpha-/- mice is Th1 in nature and can be alleviated by IgE reconstitution.

110 h Per3(-/-) phenotypes remains unclear, both are alleviated by imipramine treatment during dim night-

111 source of morbidity in elderly people could be alleviated by improvements in detection and managemen

112 re heart failure that exertional dyspnea can be alleviated by improving muscle function.

113 kinase by UTP and CTP in cell-free extracts was alleviated by increased Mg2+ concentration.

114 o ABA, sugars, and osmolites, an effect that was alleviated by increased WRI1 expression in transgeni

115 This challenge can be alleviated by increasing either the number of cells s

116 These problems may be alleviated by increasing hardware connectivity or by

117 an amino acid promoter for ppGpp in vivo can be alleviated by increasing its rate-limiting RNAP-bindi

118 Jamming could be alleviated by increasing the decomplexation rate cons

119 l transcription by the positive cofactor PC4 is alleviated by increasing amounts of TFIID, TFIIH, and

120 Toxicity was alleviated by increasing the size of the particles (

121 Both inhibition modes were alleviated by increasing cytoplasmic pH from 7.4 to

122 hosphatase activity, whereas Zn and P excess were alleviated by increasing P and Zn supply, respectiv

123 its Sgs1 chromatin association, but this can be alleviated by induced proteolysis of Mrc1 after check

124 l aberrations on replication stalling, which are alleviated by inhibition of MRE11, the nuclease resp

125 ing the hypermorphic Ser482Cys-GLS and could be alleviated by inhibition of GLS.

126 y, HIV-1-induced downregulation of SET could be alleviated by inhibition of the protease granzyme A.

127 The requirement for eyegone can be alleviated by inhibition of the wingless signaling pa

128 h defect of S. aureus tagB and tarFJ mutants was alleviated by inhibition of WTA synthesis with tunic

129 The replication arrest was alleviated by injection into oocytes of messenger RN

130 we report that transcription inhibition can be alleviated by interferon treatment and the degradatio

131 r differentiation, but that this requirement is alleviated by knocking down Otx.

132 These effects were alleviated by knocking down miR21 or miR17 and by e

133 The pH reading drift can be alleviated by laser-induced localized annealing of th

134 This limitation can be alleviated by leveraging relevant auxiliary data, suc

135 , and elevated plus maze) were higher, which were alleviated by LHb inhibition either chemogeneticall

136 This discrepancy is alleviated by light adaptation: as the mean intensity

137 k phase, caused by HFD in wild type animals, was alleviated by metformin treatment.

138 ADE17) resulted in a growth deficiency that was alleviated by methionine.

139 ch OxyR-mediated repression of transcription is alleviated by methylation of three GATC sequences in

140 Vpr-mediated G2 arrest was alleviated by methylxanthines at concentrations simi

141 st and limited availability of tracers could be alleviated by microfluidic radiosynthesis technologie

142 defects associated with Epe1 overexpression are alleviated by mutations of the SAGA histone acetyltr

143 rect interaction between Mcm10 and PCNA that is alleviated by mutations in conserved residues of the

144 Rb-induced repression of pol III activity is alleviated by mutations in the Rb pocket domain that

145 These deviations were alleviated by mutations that either inactivate the

146 ottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling a

147 Both could be alleviated by normalizing the NAD(+) redox balance ei

148 of heat stress when assessed using UTCI may be alleviated by other factors.

149 P and memory, and that these impairments can be alleviated by overexpression of EC-SOD.

150 damage induced upon lytN overexpression can be alleviated by overexpression of fmhC.

151 NFI-C-mediated repression is alleviated by overexpression of glucocorticoid recept

152 owth and branching in vivo, a phenotype that is alleviated by overexpression of the mechanosensitive

153 defect associated with the doa1Delta mutant is alleviated by overexpression of ubiquitin, but in the

154 arch synthesis, and the grain-filling defect was alleviated by overexpression of AGPase in Ospho1;2-m

155 This defect in protein degradation was alleviated by overexpression of either RPN11 or STS1

156 ription of the virulence regulator tcpPH and was alleviated by overexpression of tcpPH.

157 we hypothesized that reductive stress could be alleviated by oxidizing extracellular lactate to pyru

158 Although the natural oxidation of Cu NPs can be alleviated by passivating the surfaces with additiona

159 Kidney fibrosis in mouse models was alleviated by pharmacological inhibitors of SUMOylat

160 This inhibition is alleviated by phosphorylation by protein kinase A.

161 The effect of these substitutions could be alleviated by placing a new glycine residue at positi

162 deficit observed in 17-day-old preweanlings was alleviated by placing the pup in its home cage durin

163 d by loss of function in the dlk-1 MAP3K and were alleviated by point mutations that reduce binding t

164 cartilage destruction, the severity of which was alleviated by PPS therapy during RRV and CHIKV clini

165 These disruptive effects were alleviated by pretreating cells with a C5a receptor

166 antly, SI-induced PCD in incompatible pollen was alleviated by pretreatment with Jasp.

167 ties in streptozotocin-induced diabetic rats are alleviated by preventing the rods from dark adapting

168 Silencing was alleviated by preventing methylation, either by 5-az

169 ts that intestinal obstruction disorders can be alleviated by promoting epithelial Cl(-) secretion.

170 n addition, the carbon catabolite repression is alleviated by protease-based inverter-mediated flux r

171 Patients whose GERD symptoms were alleviated by proton pump inhibitors (PPIs) were re

172 and to determine whether any adverse effects are alleviated by providing copper with zinc.

173 al question as to how these restrictions can be alleviated by providing additional space designed wit

174 tical issues in using microarrays, they will be alleviated by rapid advances in array technology and

175 ha knockdown leads to cellular stress, which is alleviated by reduced TOR signalling or a modest incr

176 iguing possibility that neuropathic pain may be alleviated by reducing the accumulation of IgG.

177 cyte differentiation and that the defect may be alleviated by reintroduction of functional receptor.

178 igher within-group competition in humans has been alleviated by religion and culturally imposed monog

179 ant-negative form of Fu, and such inhibition is alleviated by removal of Cos2.

180 oncern in transgenic crop cultivation, could be alleviated by removing transgenes from pollen, the mo

181 The effects of the latter can be alleviated by replacing guanine with inosine, which r

182 uctive environment for beta cells, which can be alleviated by restoration of the hematopoietic system

183 not due to the absence of LcrG, because they were alleviated by restoration of LcrV expression and se

184 g telomeres leads to telomere fragility that is alleviated by restoring telomeric TRF1 levels.

185 rather vascular hyperpermeability, which can be alleviated by Resveratrol treatment.

186 njury induced by EE in IR mice was worse and was alleviated by Rhodiola pre-conditioning.

187 his arrest requires active transcription and is alleviated by RNA polymerase mutants that compensate

188 To investigate whether dyspnea could be alleviated by selective changes in leg muscle functio

189 The effects of long-term drought can be alleviated by short-term wet spring-summer months; ho

190 a significant decrease in growth, which can be alleviated by siderophores, presumably owing to the r

191 cells that the efficiency-accuracy conflict is alleviated by slowing down the elongation at structur

192 Much of the haploinsufficiency in YPD is alleviated by slowing the growth rate of each strain

193 Chronic blood shortages in the U.S. would be alleviated by small increases, in percentage terms, o

194 effect of PABPC1 specific to PAN expression is alleviated by small interfering RNA knockdown of PABP

195 RNA and ribosomes are in a masked state that is alleviated by stimulation.

196 nditions varied spatially and temporally and were alleviated by strengthening of El Nino conditions t

197 Premature dissociation of the sRNA can be alleviated by strong RNA-Hfq interactions, explaining

198 was decreased in the wri1-1 mutant but could be alleviated by sucrose.

199 Here we show that this limitation can be alleviated by sulfidation (i.e., modification by redu

200 Chelex-100-treated PMH2 growth medium, which was alleviated by supplementation with submicromolar con

201 impairments displayed in AMPKalpha2 cKO mice were alleviated by suppressing PERK activity pharmacolog

202 ive impairments displayed in AMPKa2 cKO mice were alleviated by suppressing PERK activity pharmacolog

203 rts of rats exposed to chronic hypoxia could be alleviated by sustained administration of a moderate

204 This requirement was alleviated by switching to rAAV serotype 5, which ef

205 2 replication by type I but not type II IFNs is alleviated by targeted depletion of IFITM2 expression

206 s after partial hepatectomy, which, however, is alleviated by temporal compensatory increases in the

207 the arrest of Mlh1(-/-)Rec8(TEV/TEV) oocytes is alleviated by TEV protease, even when targeted to kin

208 sis caused by the defective yeast holoenzyme are alleviated by the NC2 suppressing mutation in vivo,

209 contractile function deficits in Sod1KO mice are alleviated by the overexpression of GPx4.

210 This physiologically relevant block can be alleviated by the accessory helicase Rep or UvrD, res

211 els of NAD substrate inhibition, which could be alleviated by the addition of ATP and several other n

212 s required for choline catabolism, which can be alleviated by the addition of formate.

213 er Cu(2+) > Zn(2+) > Co(2+) > Ni(2+) and can be alleviated by the addition of metal complexing agents

214 mentally confirmed that the side effects can be alleviated by the combination of the components.

215 hearts with postinfarction LV remodeling can be alleviated by the hESC-VCs therapy.

216 cline in basipetal phloem transport that can be alleviated by the leaf's removal.

217 Such inhibition can be alleviated by the overexpression of ENG and ACVRL1 (e

218 Thus replication-transcription conflicts can be alleviated by the partial sacrifice of a mechanism th

219 Damage caused by oxidative stress may be alleviated by the polyphenols found in roselle calyce

220 human autoimmune or allergic diseases might be alleviated by the use of microbial products.

221 thereby reinforcing its own repression, this being alleviated by the trypanosome differentiation trig

222 rthermore, the effect of TI on CTCF clusters is alleviated by the acute loss of the cohesin subunit S

223 microglia NADPH oxidase activation, and this is alleviated by the CNS-penetrant antioxidant, indapami

224 Stalling at poly-Pro motifs is alleviated by the elongation factor P (EF-P).

225 in COL in the zebrafish infection model that is alleviated by the presence of TsaI homologs.

226 lesion synthesis (TLS), replication stalling is alleviated by the recruitment of specialized polymera

227 ng and increased anxiety-like behaviors, and is alleviated by the selective serotonin reuptake inhibi

228 This developmental deficit is alleviated by the simultaneous absence of maternal E-

229 ore, pain associated with PEPD, but not IEM, is alleviated by the sodium channel inhibitor carbamazep

230 , which exhibited significant apoptosis that was alleviated by the addition of ascorbic acid.

231 SAMHD1-mediated restriction was alleviated by the addition of exogenous deoxynucleos

232 ated hematopoiesis in LTBMC, and this effect was alleviated by the addition of exogenous HA.

233 This pGpG-dependent inhibition was alleviated by the addition of Orn.

234 Yet, pain in the CPPC model was alleviated by the beta-3 adrenergic antagonist SR592

235 plex formation at p(RM) and that this effect was alleviated by the deletion of 10 bp between the two

236 and increases in global DNA methylation and was alleviated by the DNA methyltransferase inhibitor 5-

237 tio=0.92 +/- 0.04; P>0.05 vs untreated), but was alleviated by the high dose of the drug (DeltaFVC ra

238 ivity to iron, as well as to H(2)O(2), which was alleviated by the iron chelator deferoxamine.

239 This defect was alleviated by the loss of NRII, and was apparently d

240 This deficiency was alleviated by the sml1 mutation.

241 the inhibitory effect of the isolated ATPase was alleviated by the T46G mutation and aggravated by th

242 lly or anaerobically had growth defects that were alleviated by the addition of exogenous iron (Fe) o

243 hese abnormal behaviors and brain activities were alleviated by the antidepressant fluoxetine treatme

244 Remarkably, NC mutant release defects were alleviated by the coexpression of a Gag protein car

245 r, used to treat cytomegalovirus infections) were alleviated by the early clinical trials.

246 evealed catalyst decomposition pathways that were alleviated by the judicious selection of reaction c

247 These disorders were alleviated by the simultaneous administration of th

248 increased intercoronal chain repulsion could be alleviated by their coassembly with linear PFS-b-PMVS

249 pairment resulting from traumatic injury can be alleviated by therapies using muscle stem cells.

250 stress and the anti-angiogenic response can be alleviated by these compounds.

251 The PLSCR1-mediated restriction was alleviated by TMPRSS2 overexpression, suggesting tha

252 leosomal arrays and that this inhibition can be alleviated by topoisomerases.

253 a natural promoter, and this repression can be alleviated by transcriptional activators Tax and CREB

254 All of the defects in opr3 are alleviated by transformation of the mutant with an O

255 etween halide electrolytes and lithium metal is alleviated by transforming the mixed electronic/ionic

256 However, organoid stress and subtype defects are alleviated by transplantation into the mouse cortex.

257 3I441M mouse model demonstrated that CCM can be alleviated by treatment with rapamycin, the mTOR inhi

258 gastric retention induced by PDE4 inhibition is alleviated by treatment with the widely used prokinet

259 ing expression of HDAC3 but not by HDAC1 and was alleviated by trichostatin A.

260 alopecia, dwarfism and cardiac abnormalities were alleviated by triiodothyronine (T3) and T4 administ

261 The TMG requirement for SAE3 splicing is alleviated by two intron mutations: a UAUUAAC to UACU

262 tion and partial volume correction (PVC) can be alleviated by use of atlas-based automatic analysis.

263 This problem could be alleviated by using alternative target tissues that c

264 We show that this problem can be alleviated by using microspheres as probes, and we es

265 with performing sensitive, long RT/PCR have been alleviated by using a mixture of DNA polymerases.

266 decomposition product(s) of the reagent and is alleviated by using a fresh solution of the deblockin

267 Plaque-induced gingivitis can be alleviated by various treatment regimens.

268 d cytotoxic function of NK cells in NOD mice is alleviated by viral infection, which enables NOD NK c

269 me of these deleterious effects of Abeta may be alleviated by vitamin D.

270 ification and trafficking defects, which can be alleviated by weak bases.

271 m on biogenesis and function of the ribosome are alleviated by YNL260c, hence, we rename YNL260c as L

272 ffusion facilitator CzcD and this repression is alleviated by Zn(II), Cd(II), Co(II), Ni(II) and Cu.