ライフサイエンスコーパス: be capable of

1 B cells are capable of a wide range of effector functions includ

2 ion are viable through early development and are capable of a wide range of stereotypic behaviors.

3 rostate cancer cells overexpressing EGFR, it was capable of (a) inhibiting EGFR in a dose-dependent m

4 st to other polymers, nucleic acid materials are capable of accessing a wide variety of rigid three-d

5 In solution, the protein is capable of accessing a high-valent Mn(V)-oxo species

6 )) binds to the N-terminus of histone H3 and is capable of accommodating common epigenetic marks on t

7 Each DBS-DNA extraction method was capable of accuracy in detecting all PWS and AS indi

8 s shown that the proposed lens-loaded cavity is capable of accurate DoA estimation.

9 ystem based on a smartphone application that is capable of accurately tracking the flow of red blood

10 In the tested cases, only the edited lines were capable of accurately reproducing the anticipated b

11 tly, a square patch element metasurface that is capable of achieving a continuous 180 degrees phase s

12 l growth at low nanomolar concentrations and is capable of achieving partial tumor regression in an M

13 okine receptors) to adopt conformations that are capable of activating beta-arrestin but not heterotr

14 Although class A GPCRs are capable of activating G proteins in a monomeric form

15 the precatalyst in a reversible fashion and is capable of activating apo-hydrogenase in in vitro ass

16 e of extracellular stimuli by growth factors is capable of activating EGR mediated transactivation of

17 Rgd3 is capable of activating Myo2, dependent on its phospho

18 Motor imagery (MI) is capable of activating the motor system and affecting

19 No current lithographic method, however, is capable of adjusting each of these variables independ

20 a third strand, but only when their strands are capable of adopting a triple-helical fold.

21 Results showed that all eight arms were capable of all four types of deformation along thei

22 GK1 mutants virally overexpressed in the VTA are capable of altering drug-associated behavior, our cu

23 screening, we identified a TTR segment that is capable of altering Abeta aggregation and toxicity, m

24 imize measures of predictive performance and are capable of analysing combinations of gene properties

25 Finally, the torch was demonstrated to be capable of analyzing single particles at a rate of at

26 rs, a new method based on deep learning that is capable of analyzing and interpreting papers in order

27 AnnoGen is capable of annotating the proprietary pragmatic featu

28 s) are suitable nonanticoagulant agents that are capable of antagonizing binding of heparin-binding p

29 The developed biosensors are capable of assaying five different types of microRNA

30 Objects in Updated Locations (OUL) task that is capable of assessing memory updating in a non-stressf

31 To maintain homeostasis, macrophages must be capable of assuming either an inflammatory or an anti

32 Lastly, CSP1-E1A-cyc(Dap6E10) was capable of attenuating mouse mortality during acute

33 unctional motile microtrap is developed that is capable of autonomously attracting, trapping, and des

34 l strains engendered cytotoxic amyloids that were capable of being propagated in endothelial cell cul

35 encircled by contractile mural cells, which are capable of bidirectional control of the length and w

36 resent in a variety of metabolic enzymes and are capable of binding diverse ligands.

37 the FeMco active site (M = Mo, V, Fe), which is capable of binding and reducing N(2) to 2NH(3).

38 energy calculations, we demonstrate that Vn is capable of binding both soluble ionic calcium and cry

39 We also observed that WT NS1 is capable of binding directly to the tandem RIG-I CARDs

40 icrofluidic valving system is devised, which is capable of biofluid sampling, routing, and compartmen

41 ibed magnetotactic protists, this flagellate is capable of biomineralizing its own anisotropic magnet

42 repurposed Phase 2-approved small molecules are capable of broadly neutralizing distinct viper venom

43 The described CNN was capable of cardiac perfusion mapping and integrated

44 s, Hendra virus (HeV) and Nipah virus (NiV), are capable of causing severe and often lethal respirato

45 ly encountered in clinical laboratories, and is capable of causing a variety of diseases, both within

46 Structures that are capable of changing shape can increase efficiency in

47 to several datasets, and show that TimeMeter is capable of characterizing complicated temporal gene e

48 on of both N(2) and O(2), whereas the latter is capable of chemisorbing O(2) at room temperature in a

49 with isolates of serotype A1, A2, A6 and A12 being capable of colonising the cell layer regardless of

50 onocytes, suggesting that neonatal monocytes are capable of colonizing inflamed tissues.

51 ulation mechanisms that sense activity alone are capable of compensating cell size.

52 mparable to one another and that each method is capable of complementing the limitations commonly ass

53 AI has proved to be capable of completing a spectrum of mundane to comple

54 tralow frequency (800 Hz) acoustic vibration is capable of concentrating and patterning submicron par

55 ell-defined transmembrane protein pores that are capable of conducting ions selectively or are large

56 Casein and WPI were capable of conserving beta-carotene against chemica

57 l networks with attention mechanisms, Tempel is capable of considering the historical residue informa

58 direct PGC-like cell induction in vitro and are capable of contributing to intra- or inter-species c

59 emory T cells infected with HIV-1 DNA, which is capable of contributing to viremia.

60 ently attached to the substrate and free TDG are capable of coordinating to Pd(II) centers, which can

61 LINE-1 elements are retrotransposons that are capable of copying their sequence to new genomic loc

62 Such a polymerase must have been capable of copying structured RNAs with high effici

63 We show that our model is capable of correctly predicting the phenotype of the

64 Our method is capable of correctly predicting the respective metabo

65 This approach is capable of coupling diverse substrates, including pha

66 AAVrh.39) which, unlike representative AAV8, are capable of crossing the blood-brain barrier (BBB), t

67 ng tissues, and; (iii) CapsNet-based design, being capable of dealing with a small number of training

68 The model is capable of dealing with heterogeneous data, including

69 models (MMLPNN, SGAM, Cforest, BGAM and SGB) are capable of delivering a high prediction accuracy for

70 Several studies developed formulations that were capable of delivering Cu(DDC)(2) complex in a singl

71 The results showed that the model is capable of describing both steady-state and kinetic p

72 epithelial cells, and many other cell types are capable of detecting infection or tissue injury, thu

73 Both novel mAbs are capable of detecting their target antigens by immuno

74 KNP-1 is capable of detecting both nephrotoxin-induced and isc

75 ion patterns observed in biopsy tissues, and was capable of detecting CRPC-NE-associated epigenetic c

76 efined signatures of four and two antibodies were capable of detecting NPC with 99.2% and 98.4% accur

77 cid extraction, and showed that these assays are capable of detection below two parasites per microli

78 introduce an in vivo barcoding strategy that is capable of determining the metastatic potential of hu

79 nally, we report that the EIS nanobiosensors are capable of differentiating the concentrations (blank

80 uno-magnetic separation of cancer cells, and is capable of differentiating between bare magnetic bead

81 our liquid biopsy-based biosensing approach is capable of differentiating healthy from early ("non-m

82 The trained CNN was capable of differentiating between benign and malign

83 at is not accompanied by clinical signs, and are capable of direct contact transmission to other cats

84 to generate a metallocarbene species, which is capable of direct insertion into an aromatic C-H bond

85 gnetic resonance (NMR) selective experiments are capable of directly analyzing crude reaction mixture

86 show that boron-alkylated BODIPY photocages are capable of directly photoreleasing both aliphatic al

87 Our results show that natural selection is capable of discovering adaptive forms of cell plastic

88 e develop an anthocyanin AUBD indicator that is capable of discriminating between fresh, spoiling, an

89 The compound is capable of disrupting the PD-1/PD-L1 complex by antag

90 vical+BVAB CM and CVF from women with BV and were capable of disrupting endocervical epithelial polar

91 invertebrates, such as sea slugs and snails, are capable of diverse locomotion modes under water.

92 Ped_draw is capable of drawing complex multi-generational pedigre

93 inity calculations, which have been shown to be capable of driving discovery projects.

94 Further, sw/OH/2017 was capable of efficient respiratory droplet transmissio

95 nder certain circumstances, cortical neurons are capable of elevating their firing for long durations

96 The nanoformulated EVG is capable of elevating intracellular drug uptake and si

97 o induce robust CD8(+) T cell responses that are capable of eliminating developing parasites in hepat

98 IVNDTGHETDENRAKVEITPNSPRAEATLGGFGSLGL, which is capable of en-hancing APP expression.

99 shown that these cells are heterogeneous and are capable of enacting diverse functions, and the compo

100 h decreased binding of strain T3SA(+), which is capable of engaging sialic acid.

101 In addition, Macrophage(nex) is capable of enhancing the therapeutic efficiency of an

102 extraction of juvenile bovine tendons, which is capable of enhancing transforming growth factor-beta

103 highly resolved spatial-temporal PNC models are capable of estimating ambient concentrations retrosp

104 Our data indicate that T. gondii is capable of evading host detection during the first ho

105 ports an integrated microfluidic device that was capable of executing rapid antimicrobial susceptibil

106 nt a framework that reconciles the data, and is capable of explaining the frictional behavior of faul

107 Graph representations of genomes are capable of expressing more genetic variation and can

108 te information from different sources, MtBNN is capable of extracting features from genomic sequences

109 (60) is applicable in hot carrier PSCs as it is capable of extracting hot carriers generated througho

110 that in its photoexcited state this iodonium is capable of facilitating a range of single-electron tr

111 es to drive the design of new compounds that are capable of fast and predictable reactions.

112 DISCOVER-seq is capable of finding and measuring off-targets in prima

113 refore, only 23 +/- 1% of larval neurons may be capable of firing Na(V)-dependent APs.

114 Consequently, they are capable of forming a complex with the SOS allosteric

115 Many strains of Staphylococcus epidermidis are capable of forming biofilms and are important human

116 results indicate that, in principle, monkeys are capable of forming internal models linking sound per

117 /-), but not Wld(s) (excess NAD(+)) neurons, are capable of forming spheroids that eventually rupture

118 Several trimeric compounds were found to be capable of forming co-gels with the catalytically act

119 Truncated RhsA that retains the PAAR domain is capable of forming higher-order, thermostable complex

120 We found that neocortical cells were capable of forming the selectivity for ongoing even

121 ographic region recorded over a span of days is capable of generalizing well to data from multiple ye

122 ting that striatal projection neurons (SPNs) are capable of generating beta oscillations, we show tha

123 of striatal fast-spiking interneurons (FSIs) are capable of generating delta/theta (ie, 2 to 6 Hz) an

124 actions, phase separation and self-assembly, are capable of generating exine-like patterns, providing

125 human induced pluripotent stem cells (iPSCs) are capable of generating highly pure cardiomyocyte popu

126 h genomic locus, separating transcripts that are capable of generating retrotransposition from those

127 DPs and dNDPs tested, suggesting that it may be capable of generating a broad range of nucleotide tri

128 Such a class of ultrafast wavefront shaper is capable of generating a sequence of arbitrary 2D spat

129 Slip motor ensembles were capable of generating force but unbound frequently,

130 'Infected' spores were capable of germinating, but did not propagate or tr

131 Being capable of growing at a rate comparable with natur

132 d enamel-tissue-based amelogenin nanoribbons are capable of guiding fibrous apatite nanocrystal forma

133 og of a MMP20-cleavage product of amelogenin was capable of guiding apatite mineralization.

134 The kangaroo rats were capable of harvesting far greater amounts of resour

135 The aluminum jacket design is capable of heating SEOP cells from ambient temperatur

136 Some of these systems are capable of high affinities and selectivities, raisin

137 imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy,

138 Furthermore, the model is capable of highlighting, within each document, the sp

139 Nanoparticle-based optical sensors are capable of highly sensitive and selective chemical i

140 The results show that RCGs (1 mol %) were capable of hosting and catalyzing various water-ins

141 olic databases were used to evaluate if HPAT was capable of identifying known pathways.

142 taR controls CD104(+)CCL21(+) mTEC(low) that are capable of IL-15-transpresentation for regulating NK

143 Glycan microarrays are capable of illuminating the interactions of glycan-b

144 t they interface with flexible software that is capable of image segmentation and probing a variety o

145 graph showed that recombinant HMGB1 (rHMGB1) was capable of impairing EDR of aortas from wild-type (W

146 ubacterial genomes, indicate that eukaryotes are capable of improved forms of genetic information pro

147 well as diverse human gut bacterial isolates were capable of inactivating the identified azo dye exci

148 oscillation and has shown that this approach is capable of increasing the permeability of microvessel

149 merozoite PfRH5-PfCyRPA-PfRipr (RCR) complex are capable of inducing strain-transcendent neutralizing

150 rotein, keyhole limpet hemocyanin (KLH) - to be capable of inducing broadly neutralizing responses ag

151 NC1-peptide was found to be capable of inducing BTB remodeling and spermatid rele

152 e same time, the gain of a single chromosome is capable of inducing a profound cell state transition,

153 We conclude that delivering TMS during MI is capable of inducing plastic changes in the motor syst

154 irst time that membrane-expressed RRV vCD200 is capable of inducing signal transduction via RM CD200R

155 sh that a bacterial immunotherapy for cancer is capable of inducing tumor immunity, an antitumor effe

156 West Nile, dengue, and yellow fever viruses, is capable of inducing variable degrees of protection ag

157 ptations, whereas longer-term PEMF treatment was capable of inducing related metabolic adaptations in

158 Brucella species, which are capable of infecting a wide range of hosts, offer a

159 given the increasing number of viruses that are capable of infecting and replicating within the nerv

160 NiV is capable of infecting a broad range of hosts including

161 The bacterial pathogen Staphylococcus aureus is capable of infecting a broad spectrum of host tissues

162 In vitro, HPG is capable of infecting bat and human cells, but not mou

163 ere acute respiratory syndrome coronavirus-2 is capable of infecting the gastrointestinal tract and s

164 We find that both models are capable of inferring variable birth rates and correc

165 ractoriness implies that extramedial regions are capable of influencing the brain network and generat

166 AKAP8 not only is capable of inhibiting splicing activity of the EMT-pr

167 We report that tenatoprazole is capable of inhibiting the replication of members of t

168 Till now, a large number of compounds that are capable of interacting and stabilizing thec-MYC G4 h

169 ork defines a class of bionic materials that is capable of interacting with living organisms and can

170 Similar to F13-HA, MC021-HA was capable of interacting with both A33 and B5.

171 d methodologies and engineering systems that are capable of interrogating and stimulating neural path

172 lymphocytes of the innate immune system that are capable of killing virally infected and/or cancerous

173 ingly, we observed that deep learning models are capable of learning from random vectors of appropria

174 Humans are capable of learning many new walking patterns.

175 Although bisphosphonates and tetracyclines were capable of localizing small amounts of peptidic pay

176 e real-time tracking method (3D-SMART) which is capable of locking on to single fluorophores in solut

177 at a single administration of free PEG alone was capable of markedly reducing the APA response to PEG

178 ledge, the first evidence that anti-KSHV Abs are capable of mediating ADCC responses against infected

179 r multiglomerular innervation patterns, SACs are capable of mediating odorant-specific patterns of in

180 ht-induced photocatalytic systems that would be capable of mediating single electron transfer (SET) t

181 Our results demonstrate that HMR-1 is capable of mediating embryo-wide reorganization drive

182 onstrate for the first time that eosinophils are capable of metabolic plasticity, evidenced by increa

183 our results indicate that both RMs and AGMs are capable of modeling SARS-CoV-2 infection and suggest

184 teolysis-targeting chimeras (PROTACs), which are capable of modulating protein concentrations at a po

185 Here we test whether dietary changes are capable of modulating sustained functional communica

186 al antibody-based immunoassays, our approach is capable of monitoring in-situ activity of LAP in live

187 nally expanded T cells, indicating that they are capable of mounting an immune response.

188 Our results demonstrate that epithelia are capable of mounting molecularly distinct responses t

189 These results demonstrate that RS is capable of much more sensitive diagnostics of HLB com

190 angular momentum holography technology that is capable of multiplexing up to 200 independent orbital

191 gnizes a highly conserved epitope on HIV and is capable of neutralizing > 95% of circulating viral is

192 The model is capable of odor identification from a small number of

193 ovide strong evidence that the visual system is capable of parsing the global motion into two compone

194 Several publically available tools are capable of performing such tasks; however, due to th

195 While mutant plants lacking xanthophylls are capable of photoautotrophic growth, no plants withou

196 ellular green alga Chlamydomonas reinhardtii is capable of photosynthetic H(2) production.

197 Microbes are capable of physiologically adapting to diverse envir

198 Antibodies are capable of potently and specifically binding individ

199 Here, we show that RU.521 is capable of potently and selectively inhibiting mouse

200 We also demonstrate that the 311 indicators are capable of predicting OOE hotspots at the neighborho

201 artificial neural network (ANN) models that are capable of predicting PLGA particle sizes produced b

202 The simulated results showed that the model was capable of predicting accurately moisture and temper

203 a ready for modeling and analysis), fMRIPrep is capable of preprocessing a diversity of datasets with

204 r-native conditions has been demonstrated to be capable of preserving biologically relevant complexes

205 acid analog of l-glutamate and l-glutamine, is capable of preventing long-term THC side effects.

206 pretreatment before adolescent THC exposure is capable of preventing long-term, THC-induced dysregul

207 s a therapeutic intervention and suggests EE is capable of preventing or reversing the widespread dys

208 application of persistence-based clustering, is capable of probing densely packed structures which va

209 We show that deep-learning architectures are capable of producing false-positive rates that are o

210 Strain-specific plasma cells are capable of producing neutralizing antibodies that ar

211 ly, simple linear gene expression weightings are capable of producing sinusoidal oscillations of any

212 The microprobe is capable of producing a direct current of 90 uA at a v

213 ng in a range of sizes from 1.5 to 3 mm, and is capable of producing flow rates up to 1.6 mL min(-1).

214 It is capable of producing large deformations and holding t

215 released Abbott ID Now COVID-19 assay, which is capable of producing positive results in as little as

216 This device platform is capable of producing pure plasma samples from blood t

217 genic activity, but machine learning methods are capable of prospective prediction from the molecular

218 ase (PPAD) produced by this bacterium, which is capable of protein citrullination.

219 We hypothesize that dental neurons are capable of providing mechanosensitive information to

220 s from similar deep-cave environments should be capable of providing palaeotemperature information ov

221 Thus, the model is capable of providing concentration prediction at cert

222 thods, such as the ones presented here, that are capable of quantifying cationic and zwitterionic PFA

223 we set out to develop a platform that would be capable of quantifying tissue-level functions such as

224 ntroduce a simple thermodynamic model, which is capable of quantitatively describing the kinetics of

225 d a prototype of a portable fluorometer that is capable of quickly quantifying concentrations of the

226 In addition, the virus is capable of rapid antigenic drift in order to evade pr

227 FRG) and retrotrapezoid nucleus (RTN) region are capable of rapidly responding to moderate hypoxia vi

228 uction pipeline including a CNN architecture is capable of rapidly reconstructing time-resolved volum

229 communities in SPG sediments (4.3-101.5 Ma) are capable of readily incorporating carbon and nitrogen

230 or aggregation based on network Hamiltonians is capable of recapitulating the entire process of amylo

231 rther found that these contractile pericytes are capable of receiving propagating K(+)-induced hyperp

232 It is demonstrated that both techniques are capable of recording the early stage of uniaxial flo

233 polarity yields an ionic double layer, which is capable of rectifying and switching ionic currents wi

234 A single dose of agrin is capable of reducing ischemia-reperfusion injury and i

235 t osteoblast and fibroblast cells growth and were capable of reducing bacterial load and accelerating

236 that antioxidant and redox-active molecules were capable of reducing the expression of the GraXRS re

237 zed (129)Xe magnetic resonance imaging (MRI) is capable of regional mapping of pulmonary gas-exchange

238 Results show that each model is capable of reliable predictions but the errors at hig

239 strategies, as these small, powerful fliers are capable of remaining airborne even in adverse wind c

240 compartmental, logical model of the MEN that is capable of representing spatial aspects of regulation

241 onstrate that iLID opto-iTrkA and opto-iTrkB are capable of reproducing downstream ERK and Akt signal

242 -S1 (myo2-G515D), a Myosin II mutant allele, was capable of rescuing lethality caused by partial defe

243 functional magnetic resonance imaging (fMRI) are capable of resolving such changes and thus should be

244 , where at least a dozen distinct cell types are capable of responding to Hh signals.

245 d hypoxia-like transcriptional paradigm that is capable of restoring and maintaining cellular homeost

246 ative ion mobility-mass spectrometry (IM-MS) is capable of revealing much that remains unknown within

247 Accordingly, JNK inhibition is capable of reversing MAP2K7Deltaexon2-driven tumor de

248 drinking water even 24 h after acute stress, is capable of reversing the delayed enhancing effects on

249 in part on its acetylation status, and HDAC6 is capable of reversing this post-translational modifica

250 These devices are capable of selective detection of various ions with

251 ticles based on impact electrochemistry that was capable of selective detection of carbon black from

252 Although the SEPs are capable of self-renewal, they are erythroid restrict

253 Thus, a limited set of molecular components is capable of self-organizing into dynamic, micron-scale

254 on assays resealed that only CD69(High) LSCs were capable of self-renewal and were poorly proliferati

255 Stem cells are capable of sensing and processing environmental inpu

256 They are capable of sensing their neuronal environment via ma

257 puncta using these simple principles, which are capable of sequestering an enzyme and whose catalyti

258 excellent photophysical properties, Pt(2) L is capable of serving as an ideal candidate for super-re

259 We show that large populations of DSGCs are capable of signaling rapid changes in global motion.

260 MSTN and activin A are capable of signaling through a complex of type II an

261 t SigProfilerSimulator, a powerful tool that is capable of simulating the mutational landscapes of th

262 in both lobes of their empty p-orbital, they are capable of simultaneously interacting with two Lewis

263 The assay is capable of simultaneously quantifying multiple endoge

264 DSP is capable of single-cell sensitivity within an ROI usin

265 iments and simulations reveal that the cells are capable of slow but deterministic chemotaxis up a ch

266 Aspergillus niger was capable of solubilizing natural (fragments and powde

267 xtent to which intact gas-phase protein ions are capable of solvating charge, and provide the most co

268 d into nanostructures with a specific shape, is capable of spacing and arranging binding sites into a

269 Furthermore, we demonstrate that our method is capable of splitting around 6000 droplets in a few se

270 ature coordinatively saturated iron centers, are capable of strong and selective adsorption of O(2) o

271 ce of each gill lamella indicate eurypterids were capable of subaerial breathing, suggesting that boo

272 ized a fluidic device previously reported to be capable of supporting long-term three-dimensional gro

273 Foxp3(+) T-regulatory (Treg) cells are capable of suppressing immune responses.

274 inactivation of dMSNs or activation of iMSNs is capable of suppressing cue-induced reinstatement of h

275 Shown here is that the cold-wall CVD system is capable of suppressing the gas-phase reaction, and ac

276 an artificial intelligence (AI) system that is capable of surpassing human experts in breast cancer

277 t to cellular senescence and exhaustion, and are capable of switching between cell cycle dormancy and

278 s can readily respond to diverse stimuli and are capable of synthesizing and secreting a large range

279 B11, VirD4, and VirB4 in prototypical T4SSs) were capable of T4SS core complex assembly but defective

280 ermore acidic oligopeptides were observed to be capable of targeting all classes of peptides, includi

281 e that time-resolved atomic force microscopy is capable of temporally and spatially resolving the mic

282 he concept of generalized calibration, which is capable of the straightforward mapping of retention t

283 have been augmented with spaced seeds, which are capable of tolerating mismatches.

284 d them to exhibit an activated phenotype and be capable of trafficking to the lungs where their prese

285 nduced T cells had a cytotoxic phenotype and were capable of trafficking to the tumor and mediating c

286 t these defective proviruses are not silent, are capable of transcribing novel unspliced forms of HIV

287 scriptional repressors, we propose that both are capable of transcriptional activation.

288 omaterial and whether this solid biomaterial was capable of transforming into a hydrogel upon introdu

289 hat SRS patient-derived lymphoblastoid cells are capable of transporting exogenous spermine and its a

290 within scalable microfluidic chambers, which are capable of transporting human blood.

291 ed dual substrate recognition properties and is capable of transporting peptidoglycan fragments (tri-

292 These polymersome nanomotors (PNMs) are capable of traversing cellular membranes allowing in

293 mpounds with novel mechanisms of action that are capable of treating drug-resistant infections(1).

294 ime monitoring and intervention devices that are capable of treating epilepsy in a non-invasive manne

295 some of which act as primer pheromones that are capable of triggering irreversible developmental swi

296 nate (mmp) bridging ligand is reported which is capable of undergoing significant variations in its s

297 Stem cells are capable of unlimited proliferation but can be induce

298 t multimodal fusion model architectures that are capable of utilizing both pixel data from volumetric

299 owed that only the Gly-containing desaturase was capable of very-long-chain desaturation.

300 The facile acid treatment is capable of weakening the bonding of zigzag octahedral