ライフサイエンスコーパス: be complicated by

1 er, their applications as optical-gain media are complicated by a non-unity degeneracy of band-edge s

2 BACKGROUNDPediatric SARS-CoV-2 infection can be complicated by a dangerous hyperinflammatory conditio

3 on of myopia is critical, as high myopia can be complicated by a number of vision-compromising condit

4 Analysis of the developing proteome has been complicated by a lack of tools that can be easily e

5 ply that the behavior concerning UV exposure is complicated by a genetic predisposition shared with n

6 matopoietic stem cell transplantation (HSCT) is complicated by a high incidence of life-threatening i

7 alidation of models is still a challenge and is complicated by a lack of field and laboratory data.

8 eded for tool assessment and improvement but is complicated by a lack of gold standards, by extensive

9 However, the use of MSC therapies is complicated by a lack of understanding of the behavio

10 l compounds in wine, key oxidation products, is complicated by a multitude of kinetically reversible

11 ran Africa and the development of strategies is complicated by a scarcity of good data from countries

12 -7 Ma, reconstructing hominin gait evolution is complicated by a sparse fossil record and challenges

13 protection against S. epidermidis challenge was complicated by a highly efficacious innate immune re

14 Her postoperative course was complicated by a large pneumothorax after chest tube

15 ld have an iuMRI study if a future pregnancy were complicated by a fetal brain abnormality.

16 ies during the study period, 76,108 of which were complicated by a hypertensive disorder of pregnancy

17 g 137 surgical procedures analyzed, 9 (6.5%) were complicated by abnormal bleeding.

18 d immunological parameters substantially but were complicated by acute leukemia as a result of insert

19 ling the role of cytoskeleton regulators may be complicated by adaptations to experimental manipulati

20 Their use may be complicated by adverse events such as venous thromboe

21 mptoms and improves quality of life, but can be complicated by adverse neuropsychiatric side-effects,

22 rbamazine citrate (DEC) treatment of loiasis is complicated by adverse reactions that are correlated

23 Both anorexia nervosa (AN) and obesity are complicated by affective comorbidities and hypothala

24 Of 1,918,789 pregnancies, 188 were complicated by AKI treated with dialysis (incidence

25 This is complicated by alkanes being such poor ligands, meani

26 ell types from one CNS region to another and are complicated by alterations in cellular composition d

27 ommon pathogenic process underlying PMD have been complicated by an incomplete understanding of PLP1

28 is crucial for understanding DIP biology but is complicated by an array of technical issues that can

29 trum anti-inflammatory agents, but their use is complicated by an equally broad range of adverse effe

30 unt of care parents provide to the offspring is complicated by an evolutionary conflict of interest (

31 formance of ion-conducting polymer membranes is complicated by an intricate interplay between chemist

32 and Aedes albopictus remains incomplete and is complicated by an ongoing range expansion fuelled by

33 The postoperative course was complicated by an episode of hemobilia due to the ru

34 Two surgeries were complicated by an intraoperative perforation of Des

35 disease of the aorta and its large branches, is complicated by aneurysm formation, dissection, and ar

36 Treatment for gonorrhea has been complicated by antimicrobial resistance.

37 The clinical course was complicated by arterial hypotension, tachycardia, de

38 Staphylococcus aureus bacteremia cases are complicated by bacterial persistence and treatment f

39 However, the embolisation was complicated by bilateral thalamic stroke with unclea

40 piratory and cardiac failure in children but is complicated by bleeding and thrombosis.

41 BACKGROUND & AIMS: Liver cirrhosis is complicated by bleeding from portal hypertension but

42 he submitter, and mining the data in the SRA is complicated by both the amount of data and the detail

43 Data pooling was complicated by center-related differences in subject

44 t of their respective functions in pathology is complicated by changes to the macrophage phenotype du

45 e of the Y chromosome in the gambiae complex is complicated by complete F1 male hybrid sterility.

46 However, vaccine design is complicated by concern that elicited antibodies (Abs)

47 entration, the most commonly used indicator, is complicated by concomitant inflammation.

48 er, understanding the compensatory mechanism is complicated by concomitant upregulation of alpha7beta

49 ion between overweight/obesity and mortality is complicated by concomitant weight loss (WL).

50 tential and tests of these models have often been complicated by conformational changes and multisite

51 of in vitro assays beyond chemical screening is complicated by continuing limits in our knowledge of

52 ion spectroscopy and magnetic susceptibility are complicated by contributions from inactive 'spectato

53 ostic methods rely on serologic testing that are complicated by cross reactivity and therefore unable

54 His clinical course was complicated by debilitating neurological symptoms an

55 Evaluation of HIV cure strategies is complicated by defective proviruses that persist in A

56 Management was complicated by delays in diagnosis, uncertainties ab

57 f ecological contributions to this variation is complicated by differences among populations in other

58 sequencing of uncultured eukaryotic genomes is complicated by difficulties in acquiring sufficient a

59 of mangroves in achieving climate goals can be complicated by difficulty in quantifying C inputs (i.

60 lobal health problem and clinical management is complicated by difficulty in discriminating between l

61 The study of semantic representations is complicated by difficulty in disentangling perceptual

62 ver, interpretation of TWAS associations may be complicated by divergent effects of model SNPs on phe

63 is key for many biological applications, but is complicated by divergent and convergent evolution.

64 en worldwide, but establishing the cause can be complicated by diverse diagnostic approaches and vary

65 el and symptom improvement in 1 patient, but was complicated by duodenal bleeding in both patients.

66 -of-function studies of PRC2 components have been complicated by early embryonic dependence on PRC2 a

67 may cause significant short-term disability, be complicated by either a large pericardial effusion or

68 Acute decompensated heart failure (ADHF) can be complicated by electrolyte abnormalities, but the maj

69 Consequently, SSc patients may be complicated by erosive esophagitis and eventually by

70 vaccine, and vaccine development strategies are complicated by evidence of both persistent infection

71 als, realization of such hot-carrier schemes is complicated by extremely fast intraband cooling (pico

72 d speed and solar elevation, and the process is complicated by forecast errors and sparse wind measur

73 Unfortunately, the GSC literature has been complicated by frequent use of inferior cell lines

74 Chronic rhinosinusitis (CRS) is complicated by frequent acute exacerbations leading t

75 This is complicated by HA and NA residing in lipid raft-like

76 -aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose

77 Pregnancy was complicated by heart failure in 6.7% of asymptomatic

78 The procedure was complicated by hemoperitoneum in four patients (10%)

79 sion, although such observational data might be complicated by hidden confounders.

80 y methylated species using mass spectrometry are complicated by high sample diversity, competition fo

81 ned by permethylation analysis, but this can be complicated by high viscosity or poor solubility, res

82 es by conventional RNA sequencing approaches is complicated by high gene density, overlapping reading

83 Measurement of such generalization is complicated by how generalization doesn't always mani

84 sis (1,089 patients), 178 (14.4%) admissions were complicated by ICU-acquired infections (at Day 10 [

85 tting of type 1 and advanced type 2 diabetes is complicated by increased risk of hypoglycemia.

86 carotid-cavernous sinus fistula (CCF), which was complicated by increased intra-ocular pressure (IOP)

87 sing global fluorescence labeling techniques is complicated by increasing cell density and rapid embr

88 lant recipients (KTRs) with oral antibiotics is complicated by increasing resistance to trimethoprim-

89 of fusion dates is common and interpretation is complicated by increasingly precise data obtained via

90 tic ecological responses to climatic warming are complicated by interactions between thermal effects

91 tential for coral adaptation to warming seas is complicated by interactions between symbiotic partner

92 erpretation of these optogenetic experiments is complicated by interactions that may occur within the

93 lopment of diagnostic classification methods is complicated by interspecies recombination.

94 Phylogenetic analysis is complicated by interspecific gene flow and the presen

95 fficials, but estimation of the distribution is complicated by interval censoring of exposures.

96 en mortality, particularly when the syndrome is complicated by intracranial haemorrhage or brain infa

97 This pathway is complicated by involvement of the orphan receptor Tie

98 rs prior to prediction is necessary, but may be complicated by issues such as noisy data and uncertai

99 However, this task is complicated by issues of undersampling of the phospho

100 ently, isolation of TME stroma from patients is complicated by issues such as limited availability of

101 cancer stem cell phenotype, direct targeting is complicated by its expression in neurons.

102 ion of human influence on global drought has been complicated by large internal variability and the b

103 nvoluting congenital hemangiomas (RICH) that were complicated by life-threatening bleeding episodes i

104 nt lymphoproliferative disorder, which could be complicated by light chain amyloidosis (AL) amyloidos

105 However, the analysis of PTMs in EVs has been complicated by limited amounts of purified EVs, low

106 f the absolute brightness of this background is complicated by local foregrounds like the Earth's atm

107 uitous physiological states, but their study is complicated by low levels of metabolic activity.

108 Exploiting lactobacilli has been complicated by metabolic diversity, unclear species

109 ental measurement of this important property is complicated by micron-scale beam sizes, and the prese

110 culous therapies require long treatments and are complicated by multi-drug-resistant strains.

111 Interpreting these data is complicated by multiclonal infections in humans, espe

112 unctional interactions between these regions are complicated by multiple direct and indirect hippocam

113 nant patient with inflammatory bowel disease is complicated by multiple providers, misinformation, an

114 Subsequent allergy investigation is complicated by multiple simultaneous drug exposures,

115 cumenting the costs of medication behaviours is complicated by natural variation in the medicinal com

116 dentification of blasting-related NO3(-) can be complicated by other NO3(-) sources, including agricu

117 Achieving this goal is complicated by our incomplete understanding of the me

118 n of the molecular basis for this phenomenon was complicated by our inability to uncouple protein bin

119 However, the correct assignment of signals is complicated by overlapping and shifting signals in di

120 lammation using traditional immunostimulants is complicated by paracrine and autocrine signaling, whi

121 Longitudinal studies are complicated by participant dropout, which could be r

122 ers ritonavir (RTV) or cobicistat (COBI) may be complicated by pharmacokinetic interactions.

123 cation of robust PD susceptibility genes has been complicated by phenotypic diversity, underpowered a

124 in complex matrices by fluorescence methods is complicated by photodegradation, blinking, and the pr

125 ADPKD genetic diagnosis is complicated by PKD1 pseudogenes located proximal to t

126 y 90% of cases) and intramural hematoma, may be complicated by poor perfusion, aneurysm, or uncontrol

127 idity and generalizability of these findings is complicated by poor adherence to reporting guidelines

128 ructure of samples after deformation, and so are complicated by post-shock annealing and reverberatio

129 from latency causes herpes zoster, which may be complicated by postherpetic neuralgia.

130 the implementation of parallel quantum gates is complicated by potential crosstalk, especially betwee

131 parous women whose most recent pregnancy had been complicated by pre-eclampsia or eclampsia and who w

132 million births in the United States annually are complicated by preexisting diabetes.

133 Seven pregnancies (26%) were complicated by pregnancy-associated aHUS (p-aHUS),

134 may benefit appetite control but its utility is complicated by psychological influences on eating.

135 His condition was complicated by pulmonary emboli and lobar infarction

136 ) acute myeloid leukemia; however, their use is complicated by rapid development of resistance, which

137 diovascular outcomes remains unclear and has been complicated by recently revised guidelines with two

138 its structural Fe(III) atoms with Fe(II)(aq) is complicated by recrystallization models with untested

139 ogically induced remission of this condition is complicated by relapses.

140 Cryptosporidiosis was complicated by renal failure in 15 patients.

141 hage or edema.Her subsequent hospital course was complicated by renal failure requiring continuous re

142 g those undergoing vitrectomy after 3 months were complicated by retinal detachment, none of which re

143 Since somatic phylogenetics is complicated by sample heterogeneity, novel specialize

144 ematic identification of these relationships is complicated by sample, reagent, and biological variab

145 Overall, 3.6% of pregnancies (47 of 1,315) were complicated by SCEs.

146 RATIONALE: Sepsis can be complicated by secondary infections.

147 f the basin, and because interpretations can be complicated by sediment preservation, uncertainties i

148 of results using this pharmacological agent are complicated by several factors: poor SK1/2 selectivi

149 However, the analysis of microbiome data is complicated by several challenges.

150 This picture is complicated by several hybrid lineages.

151 egnant donors with a previous pregnancy that was complicated by severe PE (sPE).

152 The patient's condition was complicated by severe sepsis with positive blood cul

153 regnancies with male offspring in one family were complicated by severe polyhydramnios and prematurit

154 in tuberculosis treatment; however, its use is complicated by side-effects and challenges with relia

155 ever, conventional point-bleach measurements are complicated by signal-to-noise limitations, the need

156 on of response to specific cancer treatments is complicated by significant heterogeneity between tumo

157 promising approach, but in situ measurements are complicated by slow mass transfer of strongly hydrop

158 However, the energetics of cooperativity are complicated by solvent effects and the dynamics of i

159 However, this proposition is complicated by spatial and temporal heterogeneity.

160 tion of Fc-mediated Ab responses in macaques is complicated by species-specific differences in Fcgamm

161 However, the use-resistance association is complicated by "spillover," in which one population's

162 Severe disease is complicated by spontaneous preterm delivery and still

163 studies during infectious disease outbreaks is complicated by statistical, ethical, and logistical f

164 I) quantum yields in optically dense systems are complicated by steep tissue light gradients due to s

165 mples with pronounced topographical features is complicated by systematic and measureable shifts in t

166 e Chesapeake Bay because the bay restoration is complicated by temporally and seasonally variable nut

167 ectron-transfer (PCET) reactions in proteins are complicated by the challenge of following proton tra

168 Such comparisons are complicated by the fact that algorithms often have m

169 gnitive dysfunction; however, these findings are complicated by the fact that ApoE knock-out mice hav

170 Studies of Plasmodium vivax gene expression are complicated by the lack of in vitro culture system a

171 Many surgeries are complicated by the need to anastomose, or reconnect,

172 ongenital CMV infection (cCMVi) pathogenesis are complicated by the presence of multiple infecting ma

173 ions involving both (1)O(2) and (3)CDOM* can be complicated by the deeply interconnected nature of th

174 is a common cause of hospitalization and can be complicated by the development of acute kidney injury

175 a more native environment, data analysis may be complicated by the normally found statistical orienta

176 However, IM-based isomer analysis may be complicated by the presence of multiple gas-phase con

177 orces between such colloidal particles would be complicated by the presence of other effects, such as

178 ethods use atom level information, which can be complicated by the presence of topological permutatio

179 anding spectrum of genetic diseases that can be complicated by the syndrome of HLH.

180 text, interpreting clinical neuroimaging can be complicated by the typical changes in brain contrast,

181 ation of optimal points for intervention has been complicated by the complex networks in which these

182 Recently, this paradigm has been complicated by the demonstration that alterations i

183 ver, development of an effective vaccine has been complicated by the diversity of HCV genotypes, and

184 Prevention and treatment of SSIs have been complicated by the emergence of multidrug-resistant

185 rization of disease-associated mutations has been complicated by the enormous size of RNF213.

186 ibosome footprints is still unknown, and has been complicated by the recent observation of footprints

187 secretion functions of these AT regions has been complicated by the use of multiple overlapping and

188 equine electrocardiographic (ECG) recordings is complicated by the absence of agreed abnormality clas

189 s of childhood pulmonary tuberculosis (CPTB) is complicated by the absence of an accurate reference t

190 This task is complicated by the apparently low metabolism of these

191 ease, long-term dopamine replacement therapy is complicated by the appearance of L-DOPA-induced dyski

192 of SSR length by standard sequencing methods is complicated by the appearance of length variation int

193 assignment of the correct ribosome position is complicated by the broad length distribution of the r

194 live oils cultivar and origin authentication is complicated by the broad range of variables (e.g., mu

195 rgeting this disordered release of cytokines is complicated by the changing cytokine milieu that driv

196 Gene therapy for patients with this disorder is complicated by the complex cellular abnormalities and

197 to reduce the risk of foodborne illness but is complicated by the complexity of equipment and enviro

198 tigation of the mechanism of protein folding is complicated by the context dependence of the rates of

199 als, their use in immunocompromised patients is complicated by the development of resistance.

200 This pursuit is complicated by the difficulties of mapping functional

201 in vivo translatability of drug combinations is complicated by the disparities in drug pharmacokineti

202 development of inhibitors for these enzymes is complicated by the diversity and flexibility of their

203 hods evaluated are reproducible and reusable is complicated by the diversity of software architecture

204 Characterization of NifB-co in NifB is complicated by the dynamic nature of the assembly pro

205 rpretation of such decision-related activity is complicated by the effects of interneuronal "noise" c

206 omponent for disease eradication efforts but is complicated by the emergence of drug resistance.

207 europathic pain, but its mechanism of action is complicated by the expression of its receptors at mul

208 Estimation of this potential hazard is complicated by the fact that chemical composition, wh

209 However, characterizing these states is complicated by the fact that different oscillations a

210 n humans but understanding the role it plays is complicated by the fact that little is known about th

211 stical analysis of X-chromosomal information is complicated by the fact that males only have one copy

212 This task is complicated by the fact that many diseases are hetero

213 ollateral damage to healthy or to host cells is complicated by the fact that many proteins are very s

214 ons and translocations, determination of MRD is complicated by the fact that many treated patients ha

215 However, its inhibition is complicated by the fact that PAK4 has both kinase-dep

216 ffects the hydrogen evolution reaction (HER) is complicated by the fact that palladium absorbs hydrog

217 alysis of potential disease markers in blood is complicated by the fact that proteins in plasma show

218 Data interpretation is complicated by the fact that short sequencing reads c

219 vital for human functioning, but the process is complicated by the fact that the incoming signal is o

220 This situation is complicated by the fact that the lung has two separat

221 The process is complicated by the fact that the naphthyridine exists

222 of proteins using genetics in cycling cells is complicated by the fact that there is often a delay b

223 Handling these oligomers is complicated by the fact that they often exhibit multi

224 This situation is complicated by the fact that, unlike in adults, the t

225 struts of a foam is not well understood and is complicated by the foam microstructure.

226 We find that co-transcriptional rRNA folding is complicated by the formation of long-range RNA intera

227 reverse genetics in animal models frequently is complicated by the functional redundancy of homologou

228 g true heterozygous sites in ancient genomes is complicated by the generally limited coverage achieve

229 However, oral DNA delivery is complicated by the harsh and variable conditions enco

230 r years, the standardization of immunoassays is complicated by the heterogeneity of antibodies used a

231 Assessment and management of asthma is complicated by the heterogeneous pathophysiological m

232 losis in patients with HIV in eastern Europe is complicated by the high prevalence of multidrug-resis

233 using a live-attenuated virus as the vaccine is complicated by the humoral immune response.

234 but in this case, the pretargeting approach is complicated by the internalization of 5B1 by CA19.9-e

235 ch as single-stranded nucleic acids (ssNAs), is complicated by the interplay of chain backbone entrop

236 single-cell level with current technologies is complicated by the lack of reliable methods to stably

237 Following the fate of SMCs is complicated by the lack of specific markers for the m

238 non-intensive care unit (ICU) hospital wards is complicated by the limited availability of evidence.

239 of HIV-2 in resource-limited settings (RLS) is complicated by the limited availability of HIV-2-acti

240 act as useful solvents, but its description is complicated by the long-ranged nature of dipolar inte

241 However, analysis of 4C-Seq data is complicated by the many biases inherent to the techni

242 erstanding how climate influences ecosystems is complicated by the many correlated and interrelated i

243 ntifying associated gene regulatory pathways is complicated by the molecular complexity of the brain.

244 nfection of the central nervous system (CNS) is complicated by the mostly irreplaceable nature of neu

245 tion severity is less well understood, as it is complicated by the multifaceted nature of bacterial v

246 Restoration of the Bay is complicated by the multitude of nutrient sources, the

247 This challenge is complicated by the noise that is inherent in wireless

248 Genetic diagnosis in patients with FSGS is complicated by the nontrivial rate of variants in kno

249 Predicting nonlinear partition coefficients is complicated by the number of model parameters to fit

250 following burn injury, and sepsis diagnosis is complicated by the ongoing inflammatory response.

251 e quantification of pollutant transformation is complicated by the perturbations introduced to the su

252 However, a rational design of such tools is complicated by the poor understanding of molecular me

253 at sequence (GGGGCC); however, this approach is complicated by the presence of antisense strand trans

254 ass spectrometry (LC-MS) proteomics analyses is complicated by the presence of isobaric coeluting pep

255 rpes simplex virus 1 (HSV-1) entry mechanism is complicated by the presence of more than a dozen prot

256 andidate symptoms in retired athletes to CTE is complicated by the presence of multiple premorbid and

257 ver, documentation of angiogenesis of either is complicated by the presence of the other.

258 applied analyses using genetic associations is complicated by the probable overlap between genetic c

259 Using mAbs as therapeutic molecules is complicated by the propensity of mAbs to aggregate at

260 standard of care" approach to its management is complicated by the recognition that long-term overall

261 enetic risk associations for prostate cancer is complicated by the relatively large number of risk va

262 Pharmacologic management is complicated by the risk of immunosuppressive therapy

263 wever, therapeutic targeting of this pathway is complicated by the role of Wnt in stem cell maintenan

264 Computational modeling of the HDDA reaction is complicated by the significant diradical character th

265 nt identification of clinical candidate TCRs is complicated by the size and complexity of T cell repe

266 Estimating these trends is complicated by the sparse, heterogeneous distribution

267 me rainfall events before the historical era is complicated by the sparsity of long-term "direct" sto

268 Defining this interface on a regional scale is complicated by the spatial variability of reaction ra

269 Yet taste is complicated by the transport processes of stimuli thr

270 eatability, although a comparison of reports is complicated by the use of different methodologies and

271 s in the impaired processes in iput1 mutants is complicated by the vast compensatory changes in the s

272 This exercise was complicated by the absence of a broadly accepted, sy

273 rformed 2 months after liver transplantation was complicated by the development of acyclovir-resistan

274 experienced clinical benefit, and her course was complicated by the development of graft-related dysk

275 the prediction of triplet-induced reactivity was complicated by the presence of repair mechanisms who

276 e biological roles of their glycodomains has been complicated by their massive size, domain polymorph

277 d models of papillomavirus pathogenesis have been complicated by their strict species and tissue spec

278 red regions intercalated with folded domains is complicated by their conformational diversity and fle

279 ctly mimicking the eyes of common arthropods is complicated by their curved geometry.

280 ut of HLA class II (HLA-II) beta-chain genes is complicated by their high polymorphism.

281 al loci from which Alu transcripts originate is complicated by their highly repetitive nature.

282 Measuring infant pain is complicated by their inability to describe the experi

283 However, the study of SIM-SUMO complexes is complicated by their typically low affinity and varia

284 logical investigation of these feeding sites is complicated by their variable shape and their positio

285 C), but their interpretation and translation are complicated by tumor evolution and polyclonality acc

286 Higher MCAM expression in primary tumors may be complicated by tumor-associated or normal stromal blo

287 ment of triple negative breast cancer (TNBC) is complicated by tumor heterogeneity ranging from respo

288 n the transcriptomic landscape using RNA-seq is complicated by uncertainty in fragment assignment bec

289 Disentangling their relative importance is complicated by uncertainty regarding kill mechanisms

290 el a domain within a multidomain protein may be complicated by undesirable side reactions to noninvol

291 Accurate CNA determination is complicated by uneven genomic distribution and non-un

292 he ecology and epidemiology of the virus may be complicated by unknown sensitivity and specificity of

293 Long-term vitamin K antagonist therapy can be complicated by unstable international normalized rati

294 ress hyperexcitability; however, these drugs are complicated by unwanted effects on motor, central ne

295 Variant matching is complicated by variants that have multiple equivalent

296 irus type 1 (HIV-1) vaccine development that is complicated by variations in envelope (Env) subtype a

297 Interpretation of the data is complicated by variations in STH infection intensity

298 ndolent myeloproliferative neoplasm that may be complicated by vascular events, including both thromb

299 reconstitute B-cell and NK-cell immunity and was complicated by vector-related leukemia.

300 His stay in the intensive care unit was complicated by ventilator-associated pneumonia.