ライフサイエンスコーパス: be compromised

1 cGAMP, suggesting that the STING pathway may be compromised.

2 mph drainage into mesenteric lymph nodes may be compromised.

3 sible and clinical efficacy does not seem to be compromised.

4 ructural integrity of magnet rungs would not be compromised.

5 e information stored in the DNA double helix is compromised.

6 yme meets template when chromatin relocation is compromised.

7 the predominant pro-apoptotic caspase CED-3 is compromised.

8 y that is activated when protein translation is compromised.

9 unction respectively, when separase function is compromised.

10 y disease where production by canonical EPCs is compromised.

11 ost, the ability to reactivate transcription is compromised.

12 ability when the fidelity of DNA replication is compromised.

13 but that subsequent replication of the virus is compromised.

14 n the function of the cytochrome bc(1):aa(3) is compromised.

15 ht touch as painful - occurs when inhibition is compromised.

16 dly decreased and the function of the tissue is compromised.

17 er conditions in which the activity of TORC1 is compromised.

18 ty to cope with every day or acute stressors is compromised.

19 R defects, where ATM/p53-dependent apoptosis is compromised.

20 erythematosus, can arise when TREX1 function is compromised.

21 e function of caveolae as membrane reservoir is compromised.

22 n the activity of regulatory T cells (Tregs) is compromised.

23 ution to many vascular complications when it is compromised.

24 rative diseases where the cholinergic system is compromised.

25 or the cell to divide when ring constriction is compromised.

26 l as for organismal survival when DNA repair is compromised.

27 ntial for DNA repair when the Mre11 nuclease is compromised.

28 e homeostasis if one neurotransmitter system is compromised.

29 likely, and as a result the quality of care is compromised.

30 r conditions where cap-dependent translation is compromised.

31 leted in the mesenchymal cells, tumor growth is compromised.

32 d when extracellular amino acid availability is compromised.

33 hese models the production of 11-cis-retinal is compromised.

34 gesting that NLS1 function in Delta27bp MSH3 is compromised.

35 and Chlamydomonas cells when BBSome function is compromised.

36 s under conditions where proteasome function is compromised.

37 when glutamate decarboxylase (GAD) function is compromised.

38 pe of childhood seizures, cognitive outcomes are compromised.

39 limited, biotroph growth and/or development are compromised.

40 ile microglial-mediated clearance mechanisms are compromised.

41 events increased only when mismatch binding was compromised.

42 n were limited and maximal exercise capacity was compromised.

43 DSB) repair by homologous recombination (HR) was compromised.

44 re lost from the CMs, and membrane integrity was compromised.

45 ssion of structural proteins (GFAP and AQP4) was compromised.

46 development was established, but maintenance was compromised.

47 nds were exposed and cell membrane integrity was compromised.

48 re defects (NTDs) arose and dorsal extension was compromised.

49 ygotes and found that blastocyst development was compromised.

50 a-aminobutyric acidergic synaptic inhibition was compromised.

51 olgi localization when their O-glycosylation was compromised.

52 caution that ecosystem functioning may have been compromised.

53 ined under conditions in which the cytonemes were compromised.

54 y after the cessation of cuprizone treatment were compromised.

55 , whereas the responses from the fibroblasts were compromised.

56 he production of antigen-specific antibodies were compromised.

57 However, when starch synthesis is compromised, a greater proportion of the electrons is

58 e induction of phosphorylated Stat3 and RelA was compromised after IMQ treatment in the knockout mice

59 tion of an electric field, the cell membrane is compromised, allowing the delivery of exogenous mater

60 Peri-implant health was compromised among CS than vaping individuals and NS.

61 of areas where the intestinal epithelium had been compromised and demonstrated the potential use of t

62 t of this model, mechanical force production is compromised and cell proliferation is reduced in Yap

63 lpha/IL-13Ralpha1 (13R) heteroreceptor (HR), is compromised and determined whether the lack of signal

64 In cancer, cell-cell adhesion is compromised and is associated with increased cell mig

65 In aged flies, respiratory activity is compromised and the production of peroxide radicals i

66 in males when genome-wide defense mechanisms are compromised, and suggests a previously unappreciated

67 atment, the ER integrity of SNX14 (KO) cells is compromised, and both SNX14 (KO) cells and SCAR20 dis

68 ence of EFCAB9, sperm motility and fertility is compromised, and the linear arrangement of the Ca(2+)

69 Islet function and survival may be compromised as a consequence of an incomplete islet B

70 the activation of WNT/beta-catenin signaling was compromised as a consequence of LRP6 mutations.

71 n proteomics, as the sole protease for rhEPO is compromised, as no natural tryptic cleavage site is l

72 They were both precise, but trueness was compromised at the highest tested level with the Eva

73 ing at least one wild-type copy of Ppal15kDa was compromised at varying levels.

74 equilibrium with the host, but when the skin is compromised, bacteria can colonize the wound and impa

75 s cognate receptor VPAC2, circadian behavior is compromised because SCN cells cannot synchronize.

76 However, measurements of neural activity are compromised by brain movement in behaving animals.

77 tions of mature GABAergic interneurons which are compromised by early-life injury have yet to be iden

78 Recreational opportunities are compromised by extreme weather, and children may suf

79 In situ levels of levodopa are compromised by high abundance of gut bacterial tyros

80 from 1 of many mutations, after which cones are compromised by oxidative stress.

81 osure, the defenses of the airway epithelium are compromised by reductions in barrier function, impai

82 (PPARgamma), but their therapeutic benefits are compromised by severe side effects.

83 earts, however, existing in utero approaches are compromised by spontaneous fetal motion.

84 results demonstrate that the BER DNA ligases are compromised by subtle changes in all 12 possible non

85 increases dementia risk are conflicting and are compromised by the difficulty of controlling for con

86 mmes and the interpretation of their results are compromised by the lack of knowledge about the effec

87 on, the identity of those interneurons which are compromised by tissue damage during early life remai

88 ions of cellular mRNA decay and RNA splicing are compromised by Zika virus infection as well as by sf

89 The barrier function was shown to be compromised by 24 hours of exposure to high doses (17

90 ll-cell lung cancers, but their efficacy can be compromised by acquired drug resistance conferred by

91 Reproducibility in research can be compromised by both biological and technical variatio

92 len from thermophilous taxa like Betula, can be compromised by both exotic pollen fluxes and vegetati

93 t, long-term survival of the allograft might be compromised by chronic antibody-mediated rejection (C

94 ementation of such a multimodal approach can be compromised by conflicting requirements to optimize e

95 ent-control protein modules (CCPs 1-20), may be compromised by disease-linked mutations.

96 maintenance in proliferating cells that may be compromised by diverse genetic, environmental, and xe

97 ting that prevention efficacy is unlikely to be compromised by DMPA use.

98 Computers can be compromised by encoding malware in DNA sequences, and

99 sively drug-resistant tuberculosis HIV might be compromised by HIV viral failure, and emergent antire

100 CFS stability may be compromised by incomplete DNA replication and repair

101 t a low rate; the utility of avibactam might be compromised by mutations that increase this deactivat

102 However, their therapeutic efficacy can be compromised by NA changes that emerge naturally and/o

103 Their adaptive responses may however be compromised by other constraints, such as predation r

104 Regulation can be compromised by reducing the overall structure by fusi

105 Malaria vector control may be compromised by resistance to insecticides in vector p

106 In cancer cells, PP2A function can be compromised by several mechanisms, including sporadic

107 The quantification of auxin can be compromised by the breakdown of labile auxin-related

108 y neutralizing antibody (bnAb) therapies may be compromised by the preexistence of less susceptible v

109 ductance of an ultrascaled interconnect will be compromised by the thick bilayer.

110 d other marine organisms whose habitats have been compromised by climate change and other anthropogen

111 forms whose internalization properties have been compromised by genetic perturbations within the car

112 erm stability of such biophotoelectrodes has been compromised by reactive species generated under aer

113 ge complexes, but their clinical utility has been compromised by resistance.

114 The AASK-N repository urine samples have been compromised by the acetic acid preservative.

115 espread prophylactic use of TLR agonists has been compromised by the need to administer them by paren

116 onuclease activity on ssDNA but not on dsDNA is compromised by a NEIL3 Zf-GRF repeat, whereas one Zf-

117 d cervical dystonia, but therapeutic success is compromised by a non-responder rate of up to 25%, eve

118 The effectiveness in birth weight of IPTp-SP is compromised by A581G-bearing parasites, but there was

119 activity of BET protein inhibitors (BETi's) is compromised by adaptive or innate resistance in acute

120 ith conditions where healing of hard tissues is compromised by bacterial contamination.

121 pplication of layered black phosphorus (LBP) is compromised by fast decomposition in the presence of

122 mina propria once the mucosal barrier mucosa is compromised by GVHD.

123 However, this is compromised by insufficient information about the eff

124 rvival of peritoneal Escherichia coli sepsis is compromised by long-chain polyphosphates, and improve

125 aser speckle contrast imaging (LSCI) systems is compromised by motion artefacts.

126 We find that bistability is compromised by product rebinding and that unrealistic

127 ent when Cdk1-cyclin B activation at the SPB is compromised by reduction of Cut12 function.

128 photodynamic therapy, but their utilization is compromised by self-aggregation in aqueous media.

129 are effective drugs, but their clinical use is compromised by severe side effects including hypergly

130 of therapeutic peptides for diabetes therapy is compromised by short half-lives of drugs with the con

131 ve mycoses, and the efficacy of these agents is compromised by the development of drug resistance in

132 used to treat influenza, but their efficacy is compromised by the emergence of drug-resistant varian

133 However, their effectiveness is compromised by the emergence of intrinsic or acquired

134 ted when this fundamental protective barrier is compromised by the specific mechanisms of FUS-BBB ope

135 als are highly successful, but their utility is compromised by their propensity to aggregate during m

136 a is effective only within a time window and is compromised by tumor-to-tumor variation, supporting o

137 Interim performance of the resource is compromised by variable sequence overlap and modest i

138 iven boost in net primary productivity (NPP) was compromised by DeltaT-driven stress and mortality as

139 oximal region of cilia, and cilium formation was compromised by depletion of either Inturned or Fuzzy

140 blocking HIV-1 replication, but its activity was compromised by naturally occurring sequence polymorp

141 Stability was compromised by repulsive electrostatic forces origin

142 ed mechanical allodynia in both sexes, which was compromised by Tlr9 mutation or by treatment with TL

143 GK1 upregulation and cell survival functions were compromised by a pharmacological SGK1 inhibitor.

144 Predicted solutions were compromised by excessively underdetermined systems,

145 elivered the THP when it was first evaluated were compromised by the competing responsibilities of co

146 DRG tissues in both sexes, but these changes were compromised by Tlr9 mutation in male animals.

147 expression of ALP, IGFBP5 and axin2 in bone were compromised by UL.

148 ions can degrade histamine, but DAO activity is compromised compared to pregnancy samples.

149 hether the tissue integrity of NAWM in NMOSD is compromised compared to that in healthy controls and

150 it was assumed that their antitumor immunity was compromised compared with immunocompetent patients.

151 ing genes in the STTM-directed double mutant were compromised compared to the two single mutants.

152 e the endosomal system in vulnerable neurons is compromised, contributing to the removal of accumulat

153 In the absence of PLST-1, polarization was compromised, cytokinesis was delayed or failed, and

154 If this interaction is compromised, cytokinetic precursors are asymmetricall

155 and, therefore, oncolytic activity will not be compromised despite morphological heterogeneity.

156 eir performance at low temperatures (<500 K) is compromised due to their highly resistive grain bound

157 however, the physical stability over storage was compromised due to the presence of hydrolytic enzyme

158 cid, abscisic acid, and indole-3-acetic acid were compromised due to PAE9 loss of function.

159 ing of FLC and ABI5 in the atu2af65b mutants are compromised during ABA-induced flowering.

160 ons in animals whose cross-modal experiences are compromised during early life fail to develop the ab

161 that communication between conspecifics may be compromised during critical biological periods.

162 hypothesis that endothelial Ca(2+) signaling is compromised during obesity, but the underlying abnorm

163 However, when DREAM repressive function is compromised during terminal differentiation, addition

164 el of Parkinsonism, this nigro-vagal pathway was compromised during the early stages of motor deficit

165 As clinical data collection was compromised during the lockdowns, standardized surve

166 for some radiopharmaceuticals, STP accuracy was compromised (e.g., in bone marrow and tumors for (17

167 in animals whose visual-auditory experience is compromised early in life by noise-rearing can develo

168 ficient metabolism of this phytochemical may be compromised energy production.

169 ical challenge to body fluid homeostasis may be compromised following RDN.

170 MT plus-end localization of centralspindlin was compromised following EB1 depletion, which resulted

171 CDK phosphorylation in mitosis is compromised for approximately half of all mitotic CDK

172 ity; and that a mutant Notch receptor, which is compromised for assembly into the Notch transcription

173 Spatial resolution, however, is compromised for nonflat substrates, where distances f

174 In vivo, the parA (R351A) allele is compromised for partition, but its repressor activity

175 ssrS mutants lacking Bb6S RNA were compromised for infectivity by needle inoculation,

176 contrast, Mm47-deficient or knockdown cells were compromised for Nlrp3 inflammasome responses.

177 s impaired, and the electron transport chain is compromised, fueling into a vicious cycle of free rad

178 ated or declining populations, viability may be compromised further by loss of genetic diversity.

179 Dpp signaling in the ASP was compromised if disc cells lacked Synaptobrevin and S

180 involved in the encoding of episodic memory are compromised in AD mouse models.

181 embly and alphaM/beta2 integrin localization are compromised in Arpc2(-/-) cells.

182 sad6 mutants are compromised in avenacin acylation and have enhanced

183 min E deficient2 (vte2) mutant plants, which are compromised in both tocopherol and benzoquinol precu

184 nterferon production, and antiviral activity are compromised in cell cultures and mice, while autopha

185 at Hdac8-deficient hematopoietic progenitors are compromised in colony-forming cell serial replating

186 gest that these processes and neural systems are compromised in individuals with, or at risk of devel

187 Remarkably, the metabolic actions of MCH are compromised in mice lacking SIRT1 specifically in PO

188 that HY5 gene expression and protein levels are compromised in multiple myc mutants.

189 ty, and integrity of vertebrate synapses and are compromised in neurodegenerative disorders, yet the

190 cription factor Kruppel-like factor 2 (KLF2) are compromised in PAH.

191 These mutants are compromised in signalling of all TIR-NLRs tested, in

192 agy-lysosome flux and mitochondrial function are compromised in the Drosophila nervous system and SRS

193 ffers insight on the neural systems that may be compromised in cognitive aging and age-related condit

194 ntial process of learning and memory and may be compromised in degenerative diseases, such as Alzheim

195 he GTP-rich ends of GTP/GDP MTs and that may be compromised in neurodegeneration-causing tau variants

196 atrixes, while protein integrity appeared to be compromised in RHS, which led to declining protein si

197 es C suggests the ER permeability barrier to be compromised in these mutants.

198 tch-dependent anti-parasite immune responses being compromised in Notch dimer-deficient animals.

199 phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fra

200 SNpc, and to determine whether this pathway is compromised in a rat model of Parkinsonism.

201 GluR-LTD, a form of synaptic plasticity that is compromised in a severe monogenic form of autism, Fra

202 e systems, the NRF2-mediated stress response is compromised in aging and neurodegenerative diseases.

203 ekeeper of tissue homeostasis whose activity is compromised in aging guts.

204 We asked whether NPC quality control is compromised in aging mitotic cells.

205 small resistance adipose arteries, and this is compromised in arteries from diabetic patients.

206 anced MRI, showing that glymphatic transport is compromised in both early and advanced stages of hype

207 shows that nonhomologous end joining (NHEJ) is compromised in cells with ablated MEK5 protein expres

208 e-mediated degradation of autophagy cargoes, is compromised in cystinosis.

209 lony forming progenitor cell (ECFC) function is compromised in diabetes, leading to poor vascular end

210 key role in stability of mushroom spines and is compromised in different mice models of Alzheimer's d

211 nstrate that the function of striatal PDE10A is compromised in disorders where disease-associated mut

212 e PKD proteins polycystin-1 and polycystin-2 is compromised in DZIP1L-mutant cells.

213 ized for the repair of oxidative DNA damage, is compromised in Foxo3(-/-) primitive hematopoietic cel

214 This barrier is compromised in inflammatory conditions such as infect

215 rons because of evidence that their function is compromised in MDD.

216 atic lipid metabolism when the torsin system is compromised in mice.

217 6)A target, and female-specific Sxl splicing is compromised in multiple m(6)A pathway mutants.

218 a and ventromedial prefrontal cortex (vmPFC) is compromised in multiple psychiatric disorders, many o

219 hich the homeostasis of RNA binding proteins is compromised in neurological disorders through their r

220 ) is implicated in many cognitive processes, is compromised in numerous brain disorders, and exhibits

221 ngiogenin (ANG) is a human ribonuclease that is compromised in patients with amyotrophic lateral scle

222 Cognition is compromised in pediatric brain tumor survivors but th

223 ion is higher and the immunity to B. cinerea is compromised in pmei10, pmei11, and pmei12 mutants wit

224 Moreover, adhesion at apical vertices is compromised in rearranging cells, with apical tears i

225 stingly, the interaction of TFIIB with Ssu72 is compromised in rpb4Delta cells.

226 -vacuole contacts increase when NPC assembly is compromised in several nup mutants, including nup116D

227 , the generation of ROS upon flg22 treatment is compromised in the PLC2-defficient plants, suggesting

228 yelin perturbations, the blood-nerve barrier is compromised in the presence of ectopic OPCs.

229 euroinflammation but also when BBB integrity is compromised in the resting state.

230 phagocyte NADPH oxidase-mediated GAS killing is compromised in the skin.

231 reported that ischemia-induced angiogenesis is compromised in type 2 diabetic mice.

232 roles of compartmentalized signaling, which is compromised in various retinal ciliopathies.

233 use the health of upwardly mobile minorities is compromised in young adulthood.

234 However, coumarin exudation was compromised in abcg37 mutants only with respect to c

235 EAT SHOCK FACTOR A6B [HSFA6B] family member) was compromised in bzip60-2, and the HSFTF13 promoter wa

236 depolarizing potential oscillatory activity was compromised in early postnatal days as was both feed

237 and prostaglandin E synthase (Ptges/mPGES-1) was compromised in IRE1alpha-deficient myeloid cells und

238 Instead, GC treatment was compromised in mice expressing a defective GR in the

239 Prior to muscle contraction, insulin action was compromised in myotubes from the severely obese as w

240 ity, but the development of bone cancer pain was compromised in Pd1-/- mice.

241 Neurite outgrowth was compromised in primary cortical neuronal cultures de

242 the parental strain during N starvation and was compromised in TAG remobilization upon N resupply.

243 ponse to checkpoint blockade in patients and was compromised in the absence of Tcf7.

244 the stigma brush involved in pollen capture was compromised in the rr21/22/23 mutant, whereas anther

245 r21/22/23 mutant, whereas anther development was compromised in the rr24 mutant.

246 Mechanistically, IL-2 production was compromised in weakly stimulated T cells, affecting

247 fter 12 weeks of an HFD, blood flow recovery was compromised in WT mice, whereas it was fully recover

248 These dexamethasone responses were compromised in Angptl4-null mice (Angptl4(-/-)).

249 sing TNT-active GSTs AtGST-U24 and AtGST-U25 were compromised in biomass production when grown in the

250 jmj14 mutants were compromised in both local and systemic defences.

251 tivated in the apoplast by flg22 or flgII-28 were compromised in Deltawak1 plants, but PTI at the lea

252 All mutants were compromised in infectivity on N. benthamiana and pa

253 e other hand, cardiac structure and function were compromised in response to aortocaval shunt in both

254 t and glycolysis in activated CD4(+) T cells were compromised in the absence of the INSR, which was a

255 in the penumbrium of the inflammatory injury were compromised in their regenerative capacity.

256 If the metabolic gatekeepers are compromised, influx of additional glucose may fuel p

257 sm for foxc1a upregulation when its function is compromised; interestingly, the expression of another

258 virus (JCPyV), but if the host immune system is compromised, JCPyV can cause progressive multifocal l

259 ns, the organization of individual adhesions is compromised, leading to excessive actin polymerizatio

260 Bone quality in diabetic patients is compromised, leading to weaker bones and increased fr

261 When any of these resources are compromised, LLAs exhibit poor balance control compa

262 s are stronger under conditions where health is compromised, male mortality rates are higher and econ

263 TPs in vivo, and the activity of Pol epsilon is compromised more than lagging-strand polymerase Pol d

264 The patients' quality of life was compromised most by pulmonary disease.

265 ity in samples where the spectral resolution is compromised, multivariate regression methods are requ

266 of individual mature thymic epithelial cells is compromised only modestly.

267 c mice, in settings where tolerance pathways are compromised or have been genetically manipulated to

268 se situations including where MHC expression is compromised, or where conventional adaptive and/or NK

269 When fetal growth is compromised, placental insufficiency must be distingu

270 ve cognitive performance when SCN timing has been compromised, possibly by coordinating activity in t

271 the complementary UTP opposite template RDV is compromised, providing a second opportunity to inhibi

272 ion-related encoding and retrieval processes are compromised, resulting in a failure in the prioritiz

273 tained normally and neuronal differentiation is compromised: rx3-derived ff1b+ neurons, implicated in

274 Intraoperative resident autonomy has been compromised secondary to expectations for increased

275 of the translocase of the inner membrane 23 is compromised such as in temperature-sensitive mutants

276 ut mice, formation of striolar/central zones is compromised, such that they resemble extrastriolar/pe

277 ensile strength of the biofilm infected skin was compromised supporting the notion that healed wounds

278 Interestingly, when Sbf/Rab35 function is compromised, the apical plasma membrane becomes deepl

279 When ATL function is compromised, the morphology of the endoplasmic reticu

280 ever, their utility in biological fluids can be compromised through denaturation induced by physiolog

281 pathway when the ubiquitin proteasome system is compromised, thus contributing to the mechanisms targ

282 especially when barrier function in the gut is compromised to trigger aberrant inflammatory response

283 herothrombosis, and their inhibitory effects are compromised under high shear rates when VWF levels a

284 In this model, barrier function is compromised upon exposure to inflammatory factors suc

285 ument protein pp150 and the formation of vAC was compromised upon endocytic inhibition.

286 s whenever somatosensation in the intact leg was compromised via perturbations of the platform.

287 ly when normal ER membrane lipid composition is compromised, we identified pathways beyond lipid meta

288 ide insights into protective mechanisms that are compromised when nonhibernating species, such as hum

289 However, their effectiveness can be compromised when antigenic changes arise from egg-ada

290 n academic labs, persistence of the software is compromised when developers graduate, funding ceases,

291 The flexibility of DMF is compromised when devices are permanently modified wit

292 ndependent of known nucleophagy pathways but is compromised when nuclear protein export is blocked.

293 ions become accessible but chromatin opening is compromised when Oct4(defSox2) occupies these sites.

294 kpoint blockade immunotherapy for metastases was compromised when NK cells lacked heparanase.

295 A major pathway that was compromised, when TCR signaling was suboptimal, was

296 nteracting domain formed by omega6 and core1 is compromised, which may be responsible for the entropi

297 eech codes, resources mediated by nAChRs may be compromised with aging.SIGNIFICANCE STATEMENT When at

298 CT evaluation of colorectal liver metastases is compromised with modest radiation dose reduction, and

299 wledge that core integrity of reactor Unit 1 was compromised with nuclear material existing outside o

300 e proximal and distal interphalangeal joints were compromised, without interphalangeal instability.