ライフサイエンスコーパス: be developed to

1 a lipid-bilayer-supported printing technique is developed to 3D print human cortical cells in the sof

2 ed graphical user interface, called DetEdit, was developed to accelerate the editing and annotating o

3 Last, a machine learning approach was developed to accurately score patient samples for pr

4 a modified atomic layer deposition technique was developed to achieve ultra-low loadings (8-16 ppm) o

5 lations of buprenorphine and naltrexone have been developed to address issues of safety and problems

6 Imaging technologies have been developed to address these problems, but each posse

7 h-based core-shell nanosystem (Au@Rh-ICG-CM) is developed to address tumor hypoxia while achieving hi

8 d-to-end PAT monitoring and control strategy was developed to address potential deviations and ensure

9 Reference standardization was developed to address quantification and harmonizatio

10 ICOPILI, an open-sourced Perl-based pipeline was developed to address the challenges of rapidly proce

11 ny different types of mass-tag reagents have been developed to afford myriad applications.

12 lenes under aerobic oxidation conditions has been developed to afford six-membered heterocycles.

13 and a wide assortment of enolizable partners was developed to afford over 80 novel ring-fused, N-subs

14 of the database, several flexible tools have been developed to aid retrieval and analysis of the data

15 erein, a step-by-step self-assembly strategy is developed to allocate nickel (Ni) and iron (Fe) singl

16 lters and those who are not, pathways should be developed to allow young adult males to enter accommo

17 An analytical method was developed to analyze pyridalyl residues in different

18 A number of therapeutic approaches are being developed to antagonize the events preceding and f

19 Both visual and image analysis-based assays are developed to assess the immune contexture of the tum

20 of effectiveness of countermeasures (I(eff)) was developed to assess the effectiveness of countermeas

21 ye, and partial least squares (PLS) modeling was developed to assess the nitrification inhibition pot

22 An appraisal scale was developed to assess the quality of identified articl

23 Eight primary end points were developed to assess user comprehension of each of t

24 A validated prognostic model was developed to assist in determining the clinical prog

25 Procedures have been developed to automate the analysis of magnetometer

26 Software tools have been developed to automate the estimation of protein tur

27 A bioinformatics pipeline, Cenote-Taker, was developed to automatically annotate over 2500 comple

28 Customized software was developed to automatically define and selectively fo

29 should exist and therapeutic approaches may be developed to balance between aging and tumor suppress

30 ome, a new iteration of kinase inhibitors is being developed to better utilize the three-dimensional

31 This approach was developed to better-inform source characterization a

32 Because they can be developed to bind to many disease agents, antibodies

33 Diverse approaches are developed to block IL-15 action.

34 Three main types of compounds have been developed to block the principal bacterial resistan

35 ous super-resolution imaging techniques have been developed to break the diffraction-limited resoluti

36 Numerous epidemic models have been developed to capture aspects of human contact patte

37 e-exclusion reversed-phase 2D-LC-CRMS method was developed to capture a wider range of process-relate

38 (RtN!) was developed to categorize reads from massively paralle

39 Innovative imaging methods have been developed to characterise biomolecular structures d

40 A modelling approach has been developed to characterize the reactivity of folates

41 A foundational framework is developed to characterize and interpret the emergent

42 Techniques were developed to characterize membrane-inserted oligome

43 esearch, a power management system (PMS) has been developed to charge a cell phone battery based on s

44 Many methods have been developed to cluster genes on the basis of their ch

45 A number of methods have been developed to combine diverse datasets by removing t

46 An individual patient simulation model was developed to compare 5 different approaches to kidne

47 A Markov model was developed to compare the costs and effectiveness of

48 An economic model is developed to compute impact based on discounted foreg

49 Although several methods have been developed to connect the environmental footprint of

50 e-pot, multicomponent synthetic strategy has been developed to construct substituted 3,4-dihydro-2H-b

51 Numerous strategies have been developed to convert the green-fluorescent Spinach

52 In this work, a simple and effective method was developed to convert parent MFI zeolites with tetrah

53 stroke centre and telemedicine networks have been developed to coordinate the various service compone

54 differences in the analytical approach have been developed to cope with the various caveats and the

55 of antiadsorption strategies have previously been developed to cope with this adsorption, often howev

56 tic model based on the finite element method was developed to correlate with the microstructure evolv

57 A survivor information form was developed to counsel survivors about the potential h

58 many new antimicrobial dental composites are being developed to counteract the microbial challenge.

59 n is feasible, a handful of derivatives have been developed to date, which are, however, limited to d

60 evolution of the most complete GEM that has been developed to date: the E. coli GEM.

61 efins from carbonyl compounds, but none have been developed to-date.

62 PROTACs have been developed to degrade a variety of cancer targets wi

63 uide RNA-based gene drive strain, AgNosCd-1, was developed to deliver antiparasite effector molecules

64 re, an APTMS-modified paper-based device has been developed to demonstrate application in low-cost de

65 CBNE) hydrogen in mono and disaccharides has been developed to demonstrate the feasibility of detecti

66 coupled with a stochastic soil water balance is developed to demonstrate that the time lags between r

67 A stochastic modeling framework was developed to depict the whole spectrum of tumor evol

68 Various technologies have been developed to desalinate feedwater with a wide spect

69 Room temperature calorimetry methods were developed to describe the energy landscapes of six

70 Recently, the GuideScan software is developed to design CRISPR guide RNA libraries, which

71 The workflow was developed to design and fabricate a bespoke device f

72 Though numerous tools have been developed to detect circRNAs from rRNA-depleted RNA

73 An HRMS-based method has been developed to detect pig gelatin and egg white in ex

74 Several biomarkers have recently been developed to detect rejection in KT recipients, usi

75 l computational footprinting algorithms have been developed to detect TFBSs by investigating chromati

76 Herein, a novel capture platform is developed to detect RCC-CTCs through integration of d

77 Using software that was developed to detect "blobs" and report their intensi

78 -enhanced Raman spectroscopy (SERS) platform was developed to detect airborne microorganisms, continu

79 , a generic strategy of first line screening was developed to detect and identify, through PCR amplif

80 dified carbapenem inactivation method (mCIM) was developed to detect carbapenemase activity directly

81 least squares-discriminant analysis (PLS-DA) was developed to detect four common plant-derived adulte

82 To meet this need, a method was developed to detect Salmonella using luciferase repo

83 ing targeted mass spectrometry (MS), methods were developed to detect and quantitate changes in methy

84 ds.Materials and MethodsDeep learning models were developed to detect four findings (pneumothorax, op

85 orescence and photodiode array detection has been developed to determine and quantify 27 of the main

86 t-cutting two-dimensional (2D)-LC method has been developed to determine both the yield and stereosel

87 (Protein-A-Reduction-RPLC-Digestion-RPLC/MS) was developed to determine PTM levels including oxidatio

88 spectrometry, dot blots and Western blotting were developed to determine the level of Ara h 2 absorpt

89 A computer algorithm is developed to differentiate RBCs from the patient's bl

90 Another model based on a 15-gene panel was developed to differentiate histologically concerning

91 cently, new strategies and technologies have been developed to directly explore the human immune syst

92 two-dimensional gas-chromatographic patterns is developed to discriminate spoiled hazelnuts from thos

93 ain reaction (qPCR) assay using TaqMan probe was developed to discriminate bovine, porcine and fish g

94 oltammetry on a glassy carbon (GC) electrode was developed to distinguish and quantify two main chlor

95 ell orientation within 3D collagen hydrogels is developed to dynamically create various tailored micr

96 Functions have been developed to effectively visualize the inherent var

97 n of readily available hydroxycyclopropanols was developed to efficiently synthesize tetrahydrofuran

98 In this study, a comprehensive model was developed to elucidate the reaction mechanisms and s

99 A number of alignment methods have been developed to enable the integration and comparison

100 Heat shock protein (Hsp) 70 modulators are being developed to enhance the removal of toxic proteins

101 Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific

102 PheGWAS was developed to enhance exploration of phenome-wide ple

103 Various delivery systems for DSF and Cu were developed to enhance their delivery into tumors.

104 have been developed to ensure optimum execution of the stages

105 igh-yield, silicone-on-silicon wafer process is developed to ensure reproducible characteristics of t

106 age processing and particle counter software were developed to enumerate particles on paper, with the

107 Several methods have been developed to estimate low-dimensional embeddings fo

108 Computational models have been developed to estimate protein abundances from trans

109 y Syndrome During Treatment With Alirocumab) was developed to estimate costs and outcomes over a life

110 The American Healthy Homes Survey (AHHS) was developed to estimate Pb exposure from house dust an

111 rspective, a cost-consequence analysis model was developed to estimate the incremental cost needed to

112 ation included as a time-dependent covariate were developed to estimate hazard ratios for outcomes.

113 istic models such as Bliss independence have been developed to evaluate drug interactions and their c

114 mputer simulation model of the pediatric eye was developed to evaluate preretinal, intraretinal, and

115 A computer simulation model was developed to evaluate the vitreoretinal traction and

116 the ability to control stability conditions is developed to examine the system behavior at different

117 A Markov model was developed to examine the costs and health effects of

118 While a number of hypotheses have been developed to explain this phenomenon, the detailed

119 rd proteasome, and selective inhibitors have been developed to exploit this difference.

120 Many functional analysis tools have been developed to extract functional and mechanistic ins

121 tron resonance mass spectrometry (FT-ICR-MS) was developed to extract and analyze organic matter (OM)

122 urrently, several computational methods have been developed to facilitate the discovery of such non-c

123 increasingly complex co-culture systems are being developed to facilitate neuroscience research.

124 Besides, easy-to-use web interfaces were developed to facilitate data analysis and intuitive

125 Third, an ANN is developed to generalize relationships between the val

126 free oxidation of 2-substituted anilines has been developed to generate an electrophilic N-aryl nitre

127 carboboration of 1,1-bisboryl-1,3-butadiene is developed to generate enantioenriched 3,6'-bisboryl-a

128 A diastereoselective synthesis was developed to generate (E)-1-cyano-1,3-butadiene (1)

129 The workflow was developed to generate 3D printable geometry from obt

130 Herein, a dual protection strategy has been developed to give high-content SACs by nanocasting

131 Thirty-six plots were developed to grow collard greens on Prairie View A&

132 n this knowledge, novel diagnostic tools can be developed to guide clinical diagnosis of contact alle

133 Consensus statements were developed to guide clinicians managing lung cancer

134 Consensus guidelines were developed to guide the initiation of ATT in patient

135 ral automated data processing workflows have been developed to handle the immense amount of data that

136 nalysis methods and visualization tools have been developed to help evaluate and communicate whether

137 Over 60 sequence-based disorder predictors were developed to help bridge this gap.

138 gnatures based on sequencing techniques have been developed to hopefully improve predictors of the tu

139 In previous decades, several methods have been developed to identify regions with LCRs or amino ac

140 A computational framework is developed to identify biomarker genes for lung cancer

141 tical imaging technique for the murine brain was developed to identify the effects of different thera

142 Machine learning algorithms were developed to identify a combination of antigen- and

143 re, two deep learning-based detector methods were developed to identify pig postures and drinking beh

144 melting (HRM) and rhAmp(R) SNP genotyping - were developed to identify the beta-casein gene (CSN2) A

145 this retrospective study, predictive models were developed to identify undiagnosed HCV patients usin

146 sing T-shirt based on a colorimetric pattern is developed to illustrate the utility that such formats

147 Two conceptual models were developed to illustrate the impacts of PA and copin

148 investigate sperm quality and function have been developed to improve diagnosis and management.

149 ng implants and injectable depot systems are being developed to improve patient adherence.

150 LIRA was developed to improve the efficiency of histopatholog

151 A novel seawater-based pretreatment process was developed to improve the hydrolysis yield of brown (

152 esigns of novel CAR T cell products that are being developed to increase and expand the clinical bene

153 bearing Au and ligand-free Fe nano-segments, is developed to independently present tunable frequency

154 identified in 2015, various strategies have been developed to induce pyroptosis for cancer therapy,

155 fection, and universal vaccine platforms are being developed to induce these antibodies.

156 is an established BH3-mimetic for MCL-1 and was developed to induce apoptosis in cancer cells.

157 ome data, many computational approaches have been developed to infer bacterial interactions from the

158 While reference-free algorithms have been developed to infer cell-type proportions from DNA m

159 Many methods have been developed to infer the local ancestries in a set of

160 fs, uncertainty, and values, and models have been developed to inform administrative and policy decis

161 promoters (~120 base pairs), for which rules are developed to insert operators for DNA-binding protei

162 seemed to form more readily, two approaches were developed to install phosphorus bonds directly: 1)

163 However, very few models have been developed to integrate both clinical and imaging da

164 is challenge, a biomarker discovery pipeline was developed to integrate gene expression profiles from

165 cule gamma-secretase inhibitors (GSIs), have been developed to interfere with Notch receptor activati

166 An unbiased RNA-sequencing approach was developed to interrogate decitabine-induced transcri

167 A numerical approach has been developed to invert subordination processes and to

168 A radical clock system was developed to investigate single-electron transfer (S

169 this study, a novel immunocapture technology was developed to isolate blood CNPase-positive, oligoden

170 m/glucose cotransporter 2 (SGLT2) inhibitors were developed to lower blood glucose levels by inhibiti

171 In this study, an integrated approach was developed to map the epitope/paratope of PD-1/nivolu

172 nced fluorescence microscopy techniques have been developed to measure membrane receptor mobility wit

173 Finally, a low-cost, handheld POCT was developed to measure PT for human blood, yielding 70

174 A compensation strategy that was developed to measure the choriocapillaris (CC) flow

175 d-based program in Interactive Data Language was developed to measure tumor volume in (18)F-FDG PET i

176 y-tandem mass spectrometry (LC-MS/MS) assays were developed to measure arylsulfatase A (ARSA) activit

177 ome integrative analysis pipeline (M2IA) has been developed to meet the urgent needs for tools that c

178 Muskoka2 was developed to meet these needs.

179 MEMS acoustic sensors have been developed to mimic the highly-accurate sound-locati

180 Different approaches have been developed to minimize activation of protein complex

181 An MS-compatible RNA digestion buffer was developed to minimize the number of sample-transfer

182 Dimensionality reduction (DR) methods have been developed to mitigate these challenges.

183 atalyzing lysine deacetylation, respectively-was developed to model extreme mitochondrial Kac in card

184 Strategies have been developed to modify the intestinal microbiome and r

185 er the years, several classes of ligand have been developed to modulate these functions.

186 scribe a variety of chemical tools that have been developed to monitor the activity of the iCP in cel

187 rkers, i.e., dimethyl sulfide and histamine, is developed to monitor the spoilage of raw meat, fish,

188 le reconstitution of instant coffee products was developed to monitor the dynamic release of VOCs.

189 anical cues, and organ-level physiology have been developed to narrow the gap between in vitro experi

190 nse Test (kSORT) blood gene expression assay was developed to noninvasively detect acute rejection (A

191 ogrammed cell death ligand 1 (PD-L1) tracer, was developed to noninvasively determine whole-body PD-L

192 Multivariate regression models were developed to obtain predicted normative values with

193 odality spectromicroscopy imaging system has been developed to offer the essential capability of in s

194 anti-IgE antibody, ligelizumab, has recently been developed to overcome some of the limitations assoc

195 Nanoparticles have been developed to overcome the limitations of free thera

196 cause, numerous nanomedicine approaches have been developed to overcome these issues.

197 and on immunomodulatory strategies that are being developed to overcome disease recurrence after bot

198 electroanalytical nanostructured sensor has been developed to perform quantification of vitamin C in

199 Capabilities were developed to perform experiments in low earth orbit

200 A theoretical model has been developed to predict the amplitude of the cantileve

201 t-derived xenografts (PDX) and organoids are being developed to predict patient-specific chemosensiti

202 butions, based on which an ensemble approach is developed to predict the most relevant physical prope

203 The Pesticide Loss via Volatilization model was developed to predict and understand pesticide volati

204 ted standards for AVF creation, an algorithm was developed to predict AVF outcome based on imaging fi

205 From these relations, a BRT model was developed to predict base flow nitrate concentration

206 A Initiative, a DL model on knee radiographs was developed to predict both the likelihood of a patien

207 apparent diffusion coefficient (ADC) values was developed to predict for sarcoma.

208 A patient-specific, dynamic Bayesian model was developed to predict future urine output on an hourl

209 on a piecewise linear regression model that was developed to predict the boundaries (termed Theta(1)

210 ies (right bundle branch block/low voltages) was developed to predict the presence of AS-CA (area und

211 Clinical and clinical/genetic models were developed to predict 5-year freedom from SCD.

212 , a non-traditional magnetics-based approach is developed to predictably position naturally diamagnet

213 We discuss synthetic strategies that have been developed to prepare such beyond 2D crystals and hi

214 A spray drying technique was developed to prepare injectable and biodegradable po

215 triphenylphosphine (TPP) treatment strategy was developed to prepare the near-infrared emission CsPb

216 rm1 and/or specific calpain inhibitors could be developed to prevent cisplatin induced peripheral neu

217 While many experimental methods have been developed to probe either the electronic or the nuc

218 Computational approaches have been developed to process heterogeneous data into meanin

219 allenges, a suite of computational tools has been developed to process, analyse and visualize scRNA-s

220 In parallel, sophisticated tools have been developed to process, visualize and analyse trackin

221 ts developed in this study could potentially be developed to protect from SARS-CoV-2 and some other S

222 antibody with an extended half-life that is being developed to protect infants for an entire RSV sea

223 ylindazoles with N-sulfonylformaldimines has been developed to provide a variety of N-benzylarylsulfo

224 patient class, "control-normalized FRA" has been developed to provide complementary information, by

225 A dedicated portal has been developed to provide quick and focused access to th

226 uce enriched in lutein and beta-carotene are being developed to provide increased supply of dietary c

227 acking and dedicated full occlusion glasses, was developed to provide a fast, objective, and easy-to-

228 A handheld device was developed to provide anesthesia via cooling to a foc

229 fluidic thermal gel electrophoresis platform was developed to provide high-sensitivity, high-resoluti

230 Several tools have been developed to quantify niche size and overlap.

231 Here, a mathematical model is developed to quantify the dynamics of entangled netwo

232 ope dilution mass spectrometry (IDMS) method was developed to quantify the absolute hemagglutinin (HA

233 In this study, a logistic regression model was developed to quantify the risk of rabies in biting d

234 Kinetic analysis and laboratory methods were developed to quantify the SO(4)(*-) scavenging rate

235 Here, a fluorescent scleral lens sensor is developed to quantitatively measure physiological lev

236 A new method was developed to quantitatively evaluate the physical an

237 To reduce such redundancy, many tools have been developed to recognize and annotate adduct ions.

238 Two novel methodologies have been developed to record stress-strain curves for thin p

239 An effective biorefining scheme was developed to recover functional components from ling

240 ncorporate an anti-CD3 effector function are being developed to redirect T cells against these target

241 prevention and management strategies should be developed to reduce its impact.

242 able energy conversion technologies that are being developed to reduce the dependence on fossil fuels

243 A sealing criterion was developed to relate fracture aperture with the cemen

244 A method has been developed to reliably quantify the isotopic composi

245 earning reconstruction (DLR) algorithms have been developed to remove image noise.

246 al cross-platform normalization methods have been developed to remove the systematic differences betw

247 Molecularly imprinted polymers (MIPs) have been developed to replace antibodies for the recognition

248 Alternative approaches have been developed to replace the linear reference with a va

249 using half-plane point spread functions has been developed to resolve the full-range azimuth angle (

250 Several tools have been developed to resolve this problem.

251 han the licensed Sabin monovalent OPV2, have been developed to respond to ongoing polio outbreaks due

252 A theory is developed to reveal two distinct modes of transpirati

253 A growing number of optogenetic tools have been developed to reversibly control binding between two

254 cosal immunity, or as a therapeutic, has yet been developed to SARS-CoV-2.

255 SQ-short) and the STarT Back Tool (SBT) have been developed to screen for risk factors for future low

256 ther backward in time, new applications must be developed to secure "floating" (not yet absolutely da

257 y, a three-dimensional deep learning network was developed to segment the spleen on thorax-abdomen CT

258 A workflow was developed to select transformation products with the

259 Thus, the methodologies are developed to selectively obtain 4- and 5-substituted

260 Methods based on a mixture model have been developed to separate the two types of zeros and to

261 heat transfer fluid, an experimental method was developed to separate and titrate for MgO and MgOHCl

262 arbon-encapsulated radiometal chelate (FERM) was developed to serve as a platform for multimodal imag

263 m dynamics model composed of four sub-models is developed to simulate the urbanization and energy con

264 inking water (pH 6-9 and carbonate-buffered) was developed to simulate incomplete bromide (Br(-)) oxi

265 to target the PAF1-PHF5A-DDX3 complex might be developed to slow or inhibit progression of pancreati

266 To date, many computational approaches have been developed to solve the resulting bilevel optimizati

267 @Au NPs) as a signal probe, and a smartphone was developed to specifically detect ZIKV without cross-

268 e Toronto Paediatric Cancer Stage Guidelines were developed to standardise how PBCRs collect data on

269 Retinal prostheses have been developed to stimulate the inner retinal network; h

270 The liver transplant risk score (LTRS) was developed to stratify 90-day mortality of patients r

271 Several techniques have been developed to study molecular interactions and quant

272 otating ring disk electrode (RRDE) setup has been developed to study quantitatively the role of mass

273 bioinformatics computational frameworks have been developed to study viral information from host-sequ

274 Among the tools being developed to study this yeast are large cohorts of

275 this review, we highlight how protocols that were developed to study GPCR signaling can be used to id

276 While it was developed to support HIV research in Germany, the fe

277 g the gate-opening pressure of flexible MOFs is developed to tackle such a challenge.

278 Diverse methods have been developed to tailor the number of metal atoms in me

279 Many new workflows have been developed to take advantage of NGS and have placed

280 into how novel small-molecule inhibitors may be developed to target specific subpopulations of Aurora

281 Many strategies have been developed to target DCs in cancer, such as the admi

282 Many small-molecule inhibitors have been developed to target EZH2 or the PRC2 complex, with

283 chimeric antigen receptor (CAR) T cells have been developed to target latently infected CD4(+) T cell

284 inhibitors and quorum sensing inhibitors are being developed to target the carcinogenetic impact of c

285 ays using Parallel Reaction Monitoring (PRM) were developed to test whether 10 proteins pass the sequ

286 While several such approaches have been developed to this end, their installation and imple

287 co-factor balance assessment (CBA) algorithm was developed to track and categorise how ATP and NAD(P)

288 that ensure durable bioavailability need to be developed to translate this concept into a clinically

289 A variety of treatment options have been developed to treat depressive rumination of which m

290 renal glucose wasting, SGLT2 inhibitors have been developed to treat diabetes and are the newest clas

291 y ablation of the neuromyocardial interface, was developed to treat these conditions without pacemake

292 cent years, numerous analytical methods have been developed to understand cross-disciplinary constrai

293 tumor progression, few in vitro models have been developed to understand the effects of non-neoplast

294 Theoretical models that have been developed to understand the onset of polarization h

295 Here, a generic method is developed to upgrade the conventional building-coatin

296 ted nucleophilic and electrophilic chemistry was developed to vary this 5-position with carbon, nitro

297 Although various fluorescent probes have been developed to visualize such interactions, they rema

298 A new protocol was developed to visualize and summarize the chromatogra

299 New methods are being developed to yield chitosans of specific acetylati

300 ligand (68)Ga-DO3A-VS-Tuna-2 ((68)Ga-Tuna-2) was developed to yield a noninvasive imaging marker for