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3 aphy and in 45 eyes (83%) on FA; this arcade was disrupted in 48 eyes (92%) and 39 eyes (72%) on OCT
5 vides the first evidence that these networks are disrupted in a dissociable fashion with regard to th
6 mph nodes and the subsequent T-cell response are disrupted in a mouse we recently described lacking t
14 fundamental cellular/molecular process that is disrupted in a variety of psychiatric, neurological,
15 ptic strength, even when Na(V)1.2 expression was disrupted in a cell-autonomous fashion late in devel
17 ortantly, the midcell localization of YFP-p1 was disrupted in a strain that does not express FtsZ, an
18 The frequency and temporal structure of SWRs was disrupted in a transgenic mouse model of tauopathy (
20 rhythmicity of oxygen consumption rate (Vo2) was disrupted in aged obese CT-1-deficient (CT-1(-/-)) m
26 r membranes and its subcellular localization is disrupted in Alzheimer's disease, but many of its bio
28 ic metabolism in the acr2 hac1 double mutant is disrupted in an identical manner to that described fo
29 the individual's response to threat and may be disrupted in anxiety and post-trauma psychopathology.
31 pk mutant line, aimless, myosin polarization is disrupted in approximately one third of the cells, in
36 integration of social contextual information are disrupted in association with atrophy in key fronto-
37 al retardation protein (FMRP), some of which are disrupted in autism, as well as in many known autism
38 ral circuits involved with social processing are disrupted in autism, but to date no neuroimaging stu
39 er for inundating sensory information, which is disrupted in autism, schizophrenia, and other psychia
40 earning and represents a sensory filter that is disrupted in autism, schizophrenia, and several other
42 showed that the development of this circuit is disrupted in BDNF Met carriers due to insufficient BD
44 ystrophy was fully developed only when ClC-2 was disrupted in both astrocytes and oligodendrocytes.
46 ich one, two, or all three of these pathways were disrupted in both pure line and hybrid contexts.
54 st and viral chromatin is highly dynamic and is disrupted in cells undergoing an extensive lytic reac
56 Polar localization of TnaA, GroES and YqjD was disrupted in cells lacking the MinCDE proteins, sugg
58 rom CFTR to Ezrin to PI3K/AKT signaling that is disrupted in CF, and thus promotes hyper-inflammation
60 r findings show that high-gamma oscillations are disrupted in children after treatment for a brain tu
61 Evidence is accumulating that this program is disrupted in children with severe acute malnutrition
62 aberrantly down-regulated and BA homeostasis is disrupted in cholestatic mice, but the underlying mec
63 indicates that frontal-striatal connectivity is disrupted in chronic cocaine users in a baseline (res
65 ogether, renal FGF23-Klotho signaling, which is disrupted in CKD, is essential for homeostatic contro
66 transcription, splicing, and nuclear export are disrupted in clbn, either through intron retention o
68 fected by addition of one water molecule but are disrupted in clusters with one less water molecule.
69 e ezrin phosphomimetic Y353E or Y145 mutants were disrupted in colonic Caco-2 cells, similar to ezrin
72 rcuitry during postnatal development and may be disrupted in conditions that cause intellectual disab
73 thermore, we demonstrate that this mechanism is disrupted in congenital muscular dystrophy patient my
75 which hippocampal information processing may be disrupted in dementia, which may provide targets for
77 a is a highly choreographed process that can be disrupted in developing neurons by overexpressing neu
78 e that subserves critical functions that can be disrupted in developmental and degenerative disorders
81 ilable data suggest that this phenomenon may be disrupted in diseases where cytoplasmic calcium ion l
83 ster regulators of oxygen homeostasis, which is disrupted in disorders affecting the circulatory syst
84 doplasmic reticulum (ER) calcium homeostasis is disrupted in diverse pathologies, including neurodege
86 persists under constant light conditions and is disrupted in dysfunctional clock mutants, demonstrati
88 regulating gene expression in the liver that is disrupted in early metabolic liver disease and may co
90 al residues, and this membrane sequestration is disrupted in EHEC that expresses constitutively activ
91 scovered that this mechanically quiet period is disrupted in embryos with high levels of dNTPs, which
99 aberrantly activated and stem cell functions are disrupted in gastric cancer and other disorders.
103 tudies have shown that bile acid homeostasis is disrupted in HCC patients with elevated serum bile ac
104 We discovered that this surveillance pathway is disrupted in HCV-infected cells, causing potentially
105 molecule glycosylphosphatidylinositol (GPI) is disrupted in hematopoietic stem and progenitor cells
111 tudy, we provide evidence that HA catabolism is disrupted in human intestinal microvascular endotheli
112 of the core clock transcription factor BMAL1 is disrupted in human OA cartilage and in aged mouse car
113 demonstrate that the EphB1-ephrin-B1 pathway is disrupted in human stem cell derived astrocyte and mo
116 wed the nuclear/cytoplasmic Ran distribution is disrupted in Hutchinson-Gilford Progeria syndrome (HG
117 FT25 (HSPB11), the binding partner of IFT27, was disrupted in Ift27 mutant cells, and Ift25-null mice
119 hat the normal processes of brain maturation are disrupted in individuals whose mothers drank heavily
122 y are normally correlated, this relationship is disrupted in infants with high levels of physiologica
123 transamidating activity and O-GlcNAcylation is disrupted in infected cells because host hexosamine b
125 the regulation of the SCFA-MCT1-HMGCS2 axis is disrupted in K8(-/-) colonocytes, suggesting a role f
127 mation of translation-competent 60S subunits is disrupted in leukaemia-associated ribosomopathies.
129 crossed with AhCre mice; in offspring, Axin1 was disrupted in liver following injection of beta-napht
130 milar response was observed when HS function was disrupted in long bone anlagen explants by genetic,
131 roresolving signaling and metabolic pathways are disrupted in lung tissue from patients with chronic
132 nd DTI measures reported in healthy controls were disrupted in MA and MAP groups; these involved area
133 ting data indicate that the glutamate system is disrupted in major depressive disorder (MDD), and rec
135 luation, and effort-related processes, which are disrupted in many mental and emotional disorders.
137 , and sleep-wake homeostasis, behaviors that are disrupted in many psychiatric disorders such as atte
141 ing risk-taking decisions-a process shown to be disrupted in MD-is able to predict susceptibility for
142 DNA-bending proteins; one conserved AT-hook is disrupted in MeCP2-R270X, lending further support to
146 locus shows circadian oscillations, but this is disrupted in mice with bronchiole-specific ablation o
147 lation calcium activity of dorsomedial iMSNs was disrupted in mice lacking D2Rs on iMSNs, suggesting
148 chemical chaperone 4-phenylbutyric acid, but was disrupted in mice lacking the transcription factor N
154 rms a functional complex with filamin A that is disrupted in MKS and causes defects in neuronal migra
156 its strong presence in the axonal shaft, MPS is disrupted in most presynaptic boutons but is present
163 e-6-phosphate receptors (CI-MPR) in the soma is disrupted in mutant hAPP neurons, causing defects in
164 ession studies showed that chromatin binding was disrupted in mutant compared with wild-type IKZF5, a
168 nal cortex (EC) is one of the first areas to be disrupted in neurodegenerative diseases such as Alzhe
171 diate muscle development, how these pathways are disrupted in neuromuscular disorders, and advances i
172 epresentations to guide appropriate behavior is disrupted in neuropsychiatric and neurological disord
183 key roles in many cognitive functions and to be disrupted in pathological conditions, such as schizop
184 apically with the actomyosin network, which was disrupted in patient cells, causing impaired nucleok
188 en the hypothalamus and the subgenual cortex is disrupted in patients with major depression with psyc
193 on, during which positional identities could be disrupted in pola2 mutants, leading to regeneration o
195 We sought to determine: (i) whether the BBB is disrupted in Ppt1-KO mice, (ii) if so, do T(H)17-lymp
196 nt of their proteome and how these processes are disrupted in pre-malignant and malignant states.
200 Specific nodes of this tripartite network are disrupted in psychiatric diseases, divorcing areas t
203 he view that cortical information processing is disrupted in psychosis and provides new evidence that
204 y of dorsal corticostriatal circuitry, which is disrupted in psychosis patients and individuals at hi
206 cortical entrainment of STN neural activity is disrupted in R6/2 mice and may be one of the mechanis
211 gamma (30-80 Hz) and theta (4-7 Hz) ranges, are disrupted in schizophrenia and are involved in vario
212 receptors and the dopaminergic pathways that are disrupted in schizophrenia and the histologic eviden
216 central executive and default mode networks is disrupted in schizophrenia and associated with cognit
218 ociated with glutamatergic neurotransmission is disrupted in schizophrenia, but it was unknown if the
220 excitation and inhibition (EI) is thought to be disrupted in several neuropsychiatric conditions, yet
223 nt is essential in a dynamic environment and is disrupted in several neuropsychiatric disorders.
225 computations underlying cognition and might be disrupted in severe neuropsychiatric illnesses such a
228 ing in murine models of cancer cachexia that is disrupted in skeletal muscle of patients with cancer
229 We hypothesized that astrocyte functions are disrupted in SMA, exacerbating disease progression.
231 leus pacemaker, daily TSH secretion profiles are disrupted in some patients with hypothyroidism and h
234 ial for efficient and proper myelination and is disrupted in some types of congenital muscular dystro
236 ssion programs during normal development and are disrupted in specific disease states, particularly i
241 uggest that ACC glutamate control mechanisms are disrupted in T1D, which affects glutamatergic neurot
246 ophages form contacts with each other, which are disrupted in the absence of microbiome, monocyte rec
250 don progenitors and cells, only long tendons are disrupted in the Scx (-/-) mutant; short tendons app
251 the robust circadian clock in N. crassa can be disrupted in the dark when maintained in a consistent
253 results indicate that the cpTAT pathway may be disrupted in the plsp1-null mutant, and that there ar
254 robe-graphene oxide sensor elements that can be disrupted in the presence of breast cells to give flu
255 ergoes movement, codon-anticodon interaction is disrupted in the absence of EF-G, resulting in slippa
259 ent active site cleft present in PCD enzymes is disrupted in the alpha-carboxysome PCD-like protein.
260 sease aetiology is Zn(2+) homeostasis, which is disrupted in the brains of Alzheimer's disease suffer
263 lation of genes for iron-containing proteins is disrupted in the DeltaprrF1-prrF2 mutant during infec
264 RBX1-CUL1-containing SCF(FBW7) complex, and is disrupted in the disease Glomuvenous Malformation.
265 known about the extent to which methylation is disrupted in the earliest stages of CRC development.
267 lular variability in wild-type sepals, which is disrupted in the less-variable cells of ftsh4 mutants
270 en surface-adsorbed CO and interfacial water is disrupted in the presence of the two larger cations.
273 ha helix containing the ATM recognition site is disrupted in the serine isoform of RASSF1A (RASSF1A-p
275 angiotensin-II receptor, type 1, with Cav-3 was disrupted in the hypertrophic ventricular myocytes.
276 n indicated that odontoblast differentiation was disrupted in the mutant mice likely contributing to
277 findings indicated that BDNF/TrkB signalling was disrupted in the OC of Nhe6 KO mice, probably due to
283 tion [vegetative incompatibility (vic)] loci were disrupted in the chestnut blight fungus Cryphonectr
287 infected with herpes simplex virus 2 (HSV-2) are disrupted in their ability to form stress granules (
288 er immune defects, natural killer (NK) cells are disrupted in these mice, permitting efficient engraf
294 d and spatially restricted branching process is disrupted in turnout mutants we identified in a forwa
296 dshake" that conjoins the four molecules can be disrupted in vivo by intense stimulation and in vitro
297 when active transport, NBCe1, or CA activity was disrupted in vivo, corneal edema ensued and was asso