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1 Similar changes are seen when C3PO is down-regulated.
2 ransferase that methylates 1,7-paraxanthine, is down-regulated.
3 reas epithelial markers, such as E-cadherin, are down-regulated.
4 which cell division, growth, and metabolism are down-regulated.
5 ated, while genome-wide cancer-related genes are down-regulated.
6 e alignment defects in these cells when they are down-regulated.
7 sion of proteins responsible for lipogenesis was down regulated.
8 se was up-regulated, whereas pyruvate kinase was down-regulated.
9 ressed collaterals including miRNA-352 which was down-regulated.
10 e of six mitochondrion-related nuclear genes was down-regulated.
11 rs of oil-added ducks, while the C12:0 ratio was down-regulated.
12 expression of pri-miRNA161 and pri-miRNA173 was down-regulated.
13 lf5/cyclin D1 axis was up-regulated and Klf4 was down-regulated.
14 ctural genes involved in eugenol production, was down-regulated.
15 mportant neuronal marker during development, was down-regulated.
16 phA3 cytokine/tyrosine-kinase (TK) receptors were down regulated.
17 genes (DEGs) vs. fresh-frozen, 98% of which were down-regulated.
18 t levels of IRF5 mRNA and protein expression were down-regulated.
19 sed proteins a V-ATPase and a 14-3-3 protein were down-regulated.
20 over, both alpha- and gamma-ENaC transcripts were down-regulated.
21 rticipate in the Alzheimer's disease pathway were down-regulated.
22 were elevated, while neuroinflammatory genes were down-regulated.
23 ry and field, while creb and pka transcripts were down-regulated.
24 7(-/-) mice, whereas DNA damage repair genes were down-regulated.
25 ion-channel transport and cardiac conduction were down-regulated.
26 DEGs, of which 118 were up-regulated and 68 were down-regulated.
27 (IL6), and arginine decarboxylase 2 (ADC2)) were down-regulated.
28 ment such as suberin and lignin biosynthesis were down-regulated.
29 in kinase phosphatase-1 messenger RNA levels were down-regulated.
30 key iron transporters (AfuA, FhuC, and FhuD) being down-regulated.
31 ceptor beta and insulin receptor substrate 1 were down-regulated 2-fold by Kcne2 deletion, characteri
32 der anaerobic conditions, both Id1 and c-Myc are down-regulated (50-70%), and overexpression of oxyge
33 lin protein/78-kDa glucose-regulated protein was down-regulated, activating transcription factor 6, a
34 ly of transcription factors, Sox4 and Sox11, are down-regulated after the epoch of hair cell developm
40 imary human hepatocytes, SIRT1 messenger RNA was down-regulated after GCA treatment, potentially thro
42 Particularly photosynthesis-related genes are down-regulated and genes belonging to the functional
43 mples revealed that both ts-3676 and ts-4521 are down-regulated and mutated in patient tumor samples.
44 sets of 56 and 22 protein-coding genes that are down-regulated and up-regulated in pin1Delta cells,
45 ferentiation genes (KRT1, KRT10, DSC1, DSG1) being down-regulated and late differentiation genes (SPR
48 cence the canonical miRNA biogenesis pathway is down-regulated and specific miRNAs are generated by a
49 osis occurs under conditions where cyclin D1 is down-regulated and the cell cycle arrested in G2 phas
50 tion, CD86 expressed by transitional B-cells was down regulated and T-cell proliferation was reduced.
51 (mCaROCK1), we found that irisin production was down-regulated and the mice developed obesity and in
52 d 1735 differentially expressed genes (DEGs) were down-regulated and 1369 were up-regulated in cold-s
53 SD induction, auxin genes IAA, ARF and SAURs were down-regulated and circadian genes including PIF3 a
55 of the durian pulp revealed that 15 proteins were down-regulated and three other proteins were up-reg
56 In mom1-3 ovules, both SUF4 and EC1 genes are down-regulated, and EC1 genes show higher levels of
58 which is mainly stabilized by Cx43 in vivo, was down-regulated, and its characteristic staining rema
59 ant Htt neurons, fission genes Drp1 and Fis1 were down-regulated, and fusion genes Mfn1, Mfn2 and Opa
60 il-treated mutant Htt neurons, fission genes were down-regulated, and fusion genes were up-regulated,
61 known KCNE3 partners KCNC4 and KCNH2 (mERG) were down-regulated, and KCNK4 (TRAAK) was up-regulated
62 mature: 99% of them during early maturation were down-regulated, and preferentially associated with
64 1 accumulated, W1-COE and its paralog W2-COE were down-regulated, and the phenotype was nonglaucous a
67 estingly, UBR5, and to a lesser degree UBR4, were down-regulated as cellular demand for antibody expr
68 ome formation genes (needed for translation) were down-regulated as compared with unrestricted DO.
70 tion that occurs when cortical contractility is down-regulated at the junctions between those neighbo
71 IP3 as a relapse biomarker, whose expression was down regulated at a relapse compared to remission in
72 CP1 and starch synthase IIIa (SSIIIa), which was down-regulated at the protein level in the CS8 line.
74 receptor expressions studied in mouse aortas were down-regulated at 6 and 18 hours in endotoxemic mic
76 ally by GABA release: Axonal GABAA receptors are down-regulated but dendritic receptors are up-regula
77 st all differentially expressed escape genes are down-regulated but most differentially expressed ina
78 report here that Krt17 expression initially is down-regulated but later is strongly up-regulated by
79 controls, and determined that such fragments are down-regulated by 5-fold in CLLs vs. normal controls
80 Tms from diverse substrates whose activities are down-regulated by acylation but are required for bio
82 ptome analysis showed that most of the genes are down-regulated by ethylene in shoots, and a DNA bind
88 erior part of the default-mode network (DMN) is down-regulated by both normal ageing and Alzheimer's
89 2 in an autocrine manner, and PGE2 secretion is down-regulated by cell-to-cell contact, attenuating i
90 In most Brachypodium accessions BdODDSOC2 is down-regulated by cold, and in one of the winter acce
92 hyaluronic acid-CD44 independent manner that is down-regulated by inhibitors of the JAK/STAT pathway
95 by which protein synthesis in starved cells is down-regulated by phosphorylation of the universally
97 suppressor, and we establish herein that it is down-regulated by the miR-23b cluster, which is cruci
101 loop in prostate cancer: miR-190a expression was down-regulated by AR activation; YB-1 functions are
103 methylation showed that LOC146880 expression was down-regulated by DNA methylation in its promoter.
104 owed that leaf hydraulic conductance (Kleaf) was down-regulated by exogenous ABA, with strong variati
106 mitochondrial permeability transition pore, was down-regulated by miR-7 through targeting 3'-untrans
116 xtent by PKA-CQR and of the transcripts that were down-regulated by FSH, 76% were also down-regulated
117 mponents of the circadian central oscillator were down-regulated by NF and LPS, suggesting that a roo
121 l to identify multiple neuronal tissues that are down-regulated due to pathogen infection in C. elega
123 xposure or beta3-adrenergic stimulation, and is down-regulated during brown adipocyte differentiation
124 cells at the BBB, then demonstrated that DHH is down-regulated during experimental autoimmune encepha
127 p protein EZH2 (enhancer of zeste homolog 2) is down-regulated during osteoblastic differentiation of
131 d that genes related to erythroid maturation were down-regulated during acute infections, whereas imm
133 synthase, biosynthesis, and Hym hydrogenase were down-regulated during C2H2 inhibition, consistent w
135 roapoptotic tumor suppressor gene DPPIV/CD26 was down-regulated, followed by an increase in extracell
139 ant morphological changes and one week later were down-regulated gradually, while those in Modules 2
142 us genes involved in gemcitabine sensitivity are down regulated in the resistant line upon CM03 treat
143 ed from distinct genes of pre-tRNA(His), and are down-regulated in CLL 3- to 5-fold vs. normal B cell
144 mMRP-5 (all orthologs of HRGs in C. elegans) are down-regulated in heme-treated B. malayi, as compare
145 regulate oxidative stress in the lean state are down-regulated in obesity as a consequence of inflam
147 miR-214, and LHX6 expression was detected to be down-regulated in erlotinib-resistant HCC827 cells.
149 analyzed miR-133b expression and found it to be down-regulated in HCC patient samples and induced in
151 tein claudin 1 (Cldn-1) has been reported to be down-regulated in nonlesional skin of atopic dermatit
155 oplasmic tRNAs tK(UUU), tQ(UUG) and tE(UUC), is down-regulated in a proteasomal dependent fashion.
157 Interestingly, we find that Gish expression is down-regulated in aging guts and that increasing Gish
158 and qPCR indicated that the expression of FT is down-regulated in both OsbHLH068-overexpressing Arabi
159 mediated by the DNA methylase, DNMT3A, which is down-regulated in cells lacking p38alpha, but once re
161 anscript; miR-198 expression in healthy skin is down-regulated in favor of FSTL1 upon wounding, which
163 contrast to other cancers, PICK1 expression is down-regulated in grade IV astrocytic tumor cell line
168 glandin E2 (PGE2), through its receptor EP4, is down-regulated in human systemic inflammatory disease
170 Muscular secreted frizzled-related protein 2 is down-regulated in ICU-acquired weakness patients and
174 xpressed in many cancers, including RCC, and is down-regulated in metastatic versus primary ccRCC.
176 e 2 of the gibberellin biosynthesis pathway, is down-regulated in OsbZIP48(OE) and up-regulated in Os
177 which encodes a stathmin family protein and is down-regulated in PD brains, as a key regulator funct
178 trophoblast and that ETC protein expression is down-regulated in placentas of infants with intrauter
179 olved in gametogenesis in Chlamydomonas pCRY is down-regulated in pregametes and gametes, and in the
182 tive regulator of adipocyte differentiation, is down-regulated in RCC and shows a differential expres
183 deacetylase and activator of fat oxidation, is down-regulated in response to high fat feeding, the r
188 the most widely characterized family member, is down-regulated in the depressed brain and plays a pro
189 transforming growth factor-beta1 expression is down-regulated in the Lamc3(-/-) retina, and SMAD sig
190 some studies have demonstrated that miR-27b is down-regulated in the oral specimens of patients suff
191 rticoid regulated kinase 1 (SGK1) expression is down-regulated in the postmortem PFC of PTSD subjects
193 D(+)-dependent deacetylase Sirtuin 1 (SIRT1) is down-regulated in triple-negative breast cancer.
199 We found that expression of miR-3189-3p was down-regulated in astrocytoma and glioblastoma clini
200 e 3 (Sec14l3) - a putative target of Creb1 - was down-regulated in both asthma models and in NHBE cel
203 ferator-activated receptor-gamma (PPARgamma) was down-regulated in control animals after AMI and up-r
210 ysaccharides and related regulatory systems, was down-regulated in host-like media when compared to M
212 IRF5 in HCV-induced HCC, as IRF5 expression was down-regulated in livers from HCV-positive versus HC
216 nuclear factor 4A-driven gene network, which was down-regulated in mouse hepatocyte nuclear factor 4A
220 ntified a serine protein kinase, SRPK3, that was down-regulated in RMS cells and found that expressio
221 -glucose co-transporter 2 (Sglt2) expression was down-regulated in RPTs of both male and female KO mi
224 ibitor, secreted frizzled-related protein 2, was down-regulated in skeletal muscle of ICU-acquired we
228 ation found that BMP/Smad4 signaling pathway was down-regulated in the K14-cre;Bmp2(f/f);Bmp4(f/f)ame
232 xpression of multiple enamel matrix proteins was down-regulated in the mutant ameloblasts, the cleava
234 e expression of synapsin genes SYN1 and SYN2 was down-regulated in vivo and in vitro by alphaSyn olig
236 iogenesis, including c-MYC, c-MYB, and VEGF, were down-regulated in association with a decline in hyp
240 ral drug metabolism and BA transporter genes were down-regulated in Cic-L(-/-) liver, and that BA was
241 teractions and NK cell-mediated cytotoxicity were down-regulated in cKO decidua compared with control
243 In addition, Camta1, Camta2, and Nkx2-2 were down-regulated in GK rat islets, and knockdown of C
245 that play a pivotal role in memory function, were down-regulated in head trauma-related disorders.
249 TGFbeta pathway, including pSMAD2 and pERK, were down-regulated in LTBP4 mutant human dermal fibrobl
250 in A, and Growth factor-independent 1 (Gfi1) were down-regulated in Mtgr1(-/-) whole intestines and M
251 arkers (Lgr5, Olfm4, Smoc2, Msi1, and Ascl2) were down-regulated in organoids incubated with etomoxir
252 t-tagged miR in cells where PLCbeta1 or C3PO were down-regulated in PC12 cells and find substantial d
254 ies in PGK mutants showed that PGK1 and PGK3 were down-regulated in pgk3.2 and pgk1.1, respectively.
257 many glycosylation sites on surface proteins were down-regulated in statin-treated cells compared to
258 ins were differentially up-regulated and 400 were down-regulated in the fast muscle compared with slo
259 0.75, respectively; P < 0.05); both pathways were down-regulated in the greatest-ADG compared with le
260 script as well as protein levels, while they were down-regulated in the GSH-depleted phytoalexin defi
261 f the beta cell transcriptional network that were down-regulated in the Nkx2.2(KO) mice, were maintai
262 In contrast, inflammation-related genes were down-regulated in the RV and while oxidative phosph
264 sis and fatty acid biosynthesis; these genes were down-regulated in wild-type or WRI1-overexpressing
265 %) of S-palmitoylation sites on 254 proteins were down-regulated in Zdhhc13-deficient mice, represent
266 Genes involved in various metabolic pathways were down regulated, including genes involved in cell gr
267 and parathyroid hormone-like peptide (Pthlh) were down-regulated, indicating compromised Hh signaling
269 ts, but in aggressive osteosarcomas, miR-874 is down-regulated, leading to elevated CCNE1 expression
270 artery occlusion (MCAO) model of stroke, LSR was down-regulated, linking loss of LSR and pathological
272 l stages of development to define genes that are down-regulated or up-regulated by the lec1 mutation.
273 -miR-585-3p, hsa-miR-508-3p and hsa-miR-626) were down-regulated (P < 0.05; fold regulation </=-2) in
274 cohorts demonstrate that MPI gene expression is down-regulated proportionate to fibrosis in chronic l
275 nd RORgammat are up-regulated, whereas FoxP3 is down-regulated, resulting in enhanced Th1 and Th17 ex
276 Results show pro-inflammatory cytokines were down-regulated significantly post antibiotic treatm
277 gnals such as CC chemokine receptor 7 (CCR7) are down-regulated, T cell intrinsic S1PR1 is the master
278 n which the transcriptional activity of FlrA is down-regulated through a negative feedback loop.
279 ge-sharing hypothesis, most young duplicates are down-regulated to match expression levels of single-
280 ved in iodine efflux during oxidative stress are down-regulated under increasing pCO(2) , suggesting
281 DH kinase 1, highly expressed under hypoxia, is down-regulated under normoxic conditions, leading to
284 lk between AnxA8 and Wnt signalling, as both are down-regulated upon fenretinide (FR)-mediated RPE tr
286 normal human keratinocytes YIPF4 expression was down-regulated upon differentiation and this reducti
289 k, and Pi3K/Akt/mTor signaling pathway genes were down-regulated upon vitamin D supplementation.
290 production from an equivalent number of MSCs was down-regulated via gap junctional intercellular comm
292 , ferritin OsFER2 and ferredoxin OsFd1 mRNAs are down-regulated whereas the transcriptional iron regu
293 keletal organization, and cell proliferation were down-regulated, whereas stress-related proteins wer
294 2 days earlier than normal MT channels, and being down-regulated with the emergence of the normal ch
295 ing energy deficit, muscle protein synthesis is down-regulated with concomitant increases in ubiquiti
297 zed in HCC cells and anti-apoptotic proteins were down regulated with apoptosis in ~27% of the tumor
299 expression of many fewer genes, 77% of which were down-regulated with no significant enrichment of KE
300 astly, a putative target of RORbeta, Thsd7a, is down-regulated without RORbeta, and Thsd7a knock-out