ライフサイエンスコーパス: be indicated by

1 Active asthma was indicated by 1 or more physician claims for asthma.

2 nt uncertainty about the need for a PET scan was indicated by 62.3% of the respondents.

3 A physician's treatment preferences are indicated by a threshold probability, which is the p

4 logical aging among the depressed, which can be indicated by a shorter length of telomeres.

5 ing with some collective excitation mode has been indicated by a dispersion "kink".

6 Completion of the therapy process is indicated by a "Raman signal flip" between the two re

7 ve intact paranodal axoglial contacts, which is indicated by a complete lack of neurexin/contactin-as

8 he biological significance of this mechanism is indicated by a complete suppression of the ionizing r

9 y in the mutated, but still functional, step is indicated by a greatly reduced sensitivity of its rat

10 ecificity of iron/copper inhibition of NEILs is indicated by a lack of similar inhibition of OGG1, wh

11 An atmospheric wetting effect in summer is indicated by a maximum increase in water vapour mixin

12 This is indicated by a reduction in, or absence of, transient

13 idence for a radical-based cascade mechanism is indicated by a series of experimental results.

14 tion showed a lower level of toxicity, which is indicated by a steady increase in body weight of mice

15 t is competent for hydride transfer and that is indicated by a strong charge-transfer interaction.

16 leading to their accumulation in the bulges is indicated by a strongly reduced response to mobilizat

17 f a stable N2 nanobubble at the Pt electrode is indicated by a sudden drop in voltammetric current, a

18 Inflammation was indicated by a C-reactive protein (CRP) concentratio

19 ift from IgM to IgG, and affinity maturation was indicated by a change from mostly low affinity IgM a

20 Psychological distress was indicated by a clinical diagnosis of depression, anx

21 Enzyme inhibition was indicated by a decrease in product formation detecte

22 A defect in cell polarity was indicated by a failure of the microtubule-organizing

23 Dysregulation of B lymphocytes was indicated by a marked disruption of peripheral B cel

24 filter is severely phosphorus limited, which was indicated by a PHO:GLY greater than 154 under the co

25 capability of the proposed scoring algorithm was indicated by a receiver operating characteristic cur

26 Democracy was indicated by a score greater than 0 in the Polity2 i

27 The main outcome, CMD, was indicated by a score of 12 or above on the Revised C

28 Class switching was indicated by a shift from IgM to IgG, and affinity m

29 This was indicated by a strict negative correlation reported

30 Defects in vascular remodeling were indicated by a marked reduction in the branching co

31 ents showed positive clinical effects, which were indicated by a reduction in AVH scores (p </= .001)

32 The relevance of these findings is indicated by (a) the hypertension that results in mic

33 Liver injury was indicated by abnormal serum ALT activity (>43 U/L).

34 Adhesion is indicated by accumulation of CD2 and CD58 in the cell

35 for beta-catenin in basal cell proliferation was indicated by activation of the TOPGal transgene on p

36 Deficiency of apical retinal neuroepithelium is indicated by altered localization of apical junction

37 The arrival of humans is indicated by an abrupt increase in coprostanol (and i

38 A genetic etiology is indicated by an association of the hypoplastic left h

39 vidence of excitation-contraction uncoupling is indicated by an elevation in diastolic calcium that i

40 Although a genetic etiology is indicated by an increased recurrence risk, sporadic o

41 ss in the TLR2(-/-) mice than in the WT mice was indicated by an elevation in auditory-evoked brain s

42 intrinsic problems with the oligodendrocyte was indicated by an impaired ability of oligodendrocytes

43 d to the increase in oxidative stress, which was indicated by an increase in cytosolic 8-iso prostagl

44 ate effect of {Mo(36)} to MB wheel synthesis was indicated by an increase in the yield and rate of pr

45 ID was indicated by an SF concentration <15 mug/L.

46 de Ge-H bonds oriented normal to the surface was indicated by angle-dependent Fourier-transform infra

47 nd high-pressure barosensory activity, which was indicated by arterial blood pressure (BLPR).

48 Shorter intervals may be indicated by associated adenoma findings (see "Guidel

49 Chemosensitivity was indicated by augmentation of AP firing frequency and

50 role for Insv in transcriptional repression was indicated by binding of Insv to Su(H), and by strong

51 ormance is the overcapacity developed, which is indicated by biofilm thickness measurements and mathe

52 However, increased polarity of empty capsids was indicated by bis-ANS binding, something not seen for

53 olecules involved in FDC-B-cell interactions are indicated by blocking the ligands and receptors on F

54 de bodies on infusion of activated platelets was indicated by both elevation of plasma VWF levels and

55 tection from vaccination in the prior season was indicated by both VE and serologic results.

56 tween the small and large ribosomal subunits are indicated by CG interactions with large spring const

57 Altered integrin signaling was indicated by changes in the distribution of vinculin

58 Mass changes due to DNA hybridization were indicated by changes of quartz resonance frequencie

59 hormone in the outer region of the membrane is indicated by characteristic changes in the transition

60 n the structure of the substrate-free domain is indicated by chemical shifts.

61 The formation of the G-quadruplex structure was indicated by circular dichroism (CD) spectroscopy an

62 domain of endopin 2 with papain and elastase were indicated by cleavage of endopin 2 near the predict

63 Conserved microsynteny of the CpCYC-b region is indicated by colinearity of two to four genes between

64 The role of local IGFBPs was indicated by comparing the activities of IGF-I and d

65 In addition, potential glycan changes were indicated by comparing proteins in control and canc

66 primary human monocyte rolling and adhesion was indicated by competition studies in which addition o

67 Abiotic patterns of TCE degradation were indicated by compound-specific stable isotope data

68 The presence of LA was indicated by confluent or patchy areas of hyperinten

69 This is indicated by continuous Col-9 expression in SE limbs,

70 n 6hydroxy-1-indanone and aromatic aldehydes is indicated by cooperative interactions between p-methy

71 That this source is photomediated is indicated by correlations between the diurnal cycles

72 possible location of this secondary site has been indicated by crystallographic studies as two symmet

73 Impaired cell adhesion and epithelialization are indicated by decreased E-cadherin and NCAM expressio

74 sistance to parathyroid hormone (PTH), which is indicated by decreased double-labeled surface and ost

75 This is indicated by decreased expression of the tendon-relat

76 s accompanied by synaptic dysfunction, which is indicated by decreased fluorodeoxyglucose uptake on P

77 hepatic immune activation by IFNalpha, which is indicated by decreased levels of CXCL10 and CXCL11 an

78 The functional importance of MAGE-11 was indicated by decreased human AR regulation of an and

79 istic role of miR-155 in TNFalpha regulation was indicated by decreased TNFalpha levels in alcohol-tr

80 This was indicated by decreases in airway hyperreactivity and

81 This inhibition of cell cycle progression was indicated by delayed progression into nocodazole-ind

82 egative effects of further N-only deposition were indicated by delayed spring CO2 uptake.

83 Divergent selection is indicated by different omega's between clades, such a

84 rity in the pharmacokinetics of rhEndostatin was indicated by dose-proportionate increases in the are

85 ads to marked oxidative stress in cells that is indicated by elevated intracellular reactive oxygen s

86 Severe RV dysfunction was indicated by elevated end-diastolic pressure (11.3+/

87 Hepatocyte necrosis was indicated by elevated serum high-mobility group box

88 As in clinical studies, attentional bias was indicated by elongated response times on trials with

89 ive response and not an adverse toxic effect was indicated by enhanced survival of ribosome mutants a

90 This was indicated by enhancement of hydrogen peroxide-respon

91 ween the active site and the allosteric site were indicated by equilibrium binding experiments, which

92 Oral health was indicated by extent of gingival bleeding, extent of

93 UX1) in Fe-triggered lateral root elongation was indicated by Fe-responsive AUX1 promoter activities

94 Task learning was indicated by fewer errors of omission of licking and

95 inding between the active compounds and ERK2 was indicated by fluorescence quenching.

96 etween SMN and Gemin2 within single granules was indicated by fluorescence resonance energy transfer

97 is suggests that lockdown success might only be indicated by four or more daily falls.

98 In carcinogenesis, KLF5's role has been indicated by frequent genetic deletion as well as f

99 l functional organization in the human brain is indicated by gaze-adaptation experiments, in which sy

100 General applicability of the models was indicated by good performance in cross-species valid

101 etabolism or increased secretion in PNS rats was indicated by greater plasma testosterone and progest

102 Population iodine deficiency is indicated by >3% of the population with newborn thyro

103 ial pathogenesis, but a genetic contribution is indicated by heritability studies.

104 B cell activation was indicated by high phosphotyrosine levels in caps and

105 yet a greater abundance of thin, dense walls was indicated by high-resolution x-ray tomography of ste

106 MARV disease in the controls was indicated by: high titres of MARV (10(3)-10(5) plaqu

107 e L activation in infected RNase L(+/+) mice was indicated by higher levels of viral RNA in the brain

108 to septic complications after trauma, which is indicated by HP expression in particular.

109 Focal RPE damage was indicated by hyper-transmission beneath the RPE-Bruc

110 s may have a macrophage origin, despite what is indicated by immunostaining for macrophage-related ma

111 The importance of Smad complexes is indicated by impaired IL-2Ralpha induction by TGF-bet

112 ional significance of the structural changes was indicated by improved oxygenation and lung complianc

113 ct role for OX40L in regulating inflammation was indicated by improved survival, decreased cytokine p

114 These changes are indicated by increased sensitivities to SDS-mediated

115 At the cellular level, impaired neurogenesis is indicated by increased early-born retinal neurons tha

116 A role for the innate immune system was indicated by increased Kupffer cell numbers with imp

117 reased treatment intensity in the EGDT group was indicated by increased use of intravenous fluids, va

118 L antiviral activity by flavivirus infection was indicated by increased viral RNA levels in the brain

119 ooperative activation of multiple mechanisms was indicated by increases in SF strengthening and gamma

120 veillance intervals (unless shorter interval is indicated by individual findings), and a CF-specific

121 independent functions of the receptor, which are indicated by its only known physiological ligand, po

122 S-1/Rab4-mediated mitochondrial accumulation is indicated by its abrogation by dominant-negative HRES

123 The d orbital aromaticity of Cu(4)Li(2) also is indicated by its atomization energy, 243.2 kcal/mol,

124 This is indicated by its highly shielded (29)Si NMR chemical

125 urn-on probe in longer-term cellular studies is indicated by its lack of influence on cell viability

126 We compared a version in which choices were indicated by key presses, the standard response in

127 This is indicated by lack of CENP-A transmission by sperm dur

128 hat the expected timing of available rewards is indicated by lever pressing.

129 A critical concentration of 0.4-1.0 microM was indicated by light scattering experiments and extrap

130 This is indicated by low levels of spontaneous microbial kill

131 This is indicated by low oxygen isotope values with strong se

132 In addition, a spin glass behavior is indicated by magnetic susceptibility measurements.

133 Such peaks are indicated by massive high-redshift radio galaxies.

134 -sheet structures in the majority of fibrils are indicated by measurements of intermolecular distance

135 This was indicated by methane degradation assays in microcosm

136 r cells could be due to promoter methylation was indicated by methylation-specific PCR analysis.

137 perspective of TRADD's role in TNF signaling was indicated by microarray gene expression analysis, wh

138 Evidence of muscle disease was indicated by muscle pain, muscle weakness and wastin

139 es within this regulatory fragment that have been indicated by mutational studies to influence prion

140 han anticipated role of NF-kappaB signalling was indicated by mutations in 11 members of the NF-kappa

141 is and its intracellular accumulation, which was indicated by neuron-specific transcript analysis.

142 The specificity of this pathway was indicated by no significant enhancement of JCV multi

143 A physiological association is indicated by observations that the level of myosin Va

144 This is indicated by observing that most of the LUV and sMLV

145 The significance of this gene signature is indicated by our demonstration of cadmium chloride- o

146 trolling the bull sperm chromatin morphology is indicated by our observation that DNA condensates for

147 o release ETH in betaftz-f1 silenced animals is indicated by persistent ETH immunoreactivity in Inka

148 A causal link for these findings is indicated by pharmacological approaches.

149 The self-renewal capacity of hHpSCs is indicated by phenotypic stability after expansion for

150 /-) mice were also found to be hypotonic, as was indicated by poor performance on the wire hanging ta

151 structural ordering of the carbon materials is indicated by powder XRD patterns with at least two we

152 e outermost layers of the B. anthracis spore is indicated by previous proteomic analyses of the exosp

153 ge is about 20-40 million years younger than was indicated by previous molecular analyses.

154 ose effects at least three years longer than was indicated by previous, data-limited evaluations.

155 iation of food products and ingredients must be indicated by proper labeling.

156 of endopin 2C with cathepsin L and elastase were indicated by protease cleavage of the RSL region be

157 uch tasks, to a version in which the choices were indicated by reaching movements, which affords exec

158 for the coupled bioluminescence reaction has been indicated by recent kinetic studies.

159 cient serotonin neurotransmission in suicide is indicated by reduced brainstem serotonin (5-HT) and 5

160 This was indicated by reduced BrdU incorporation and decrease

161 xorubicin impaired muscle performance, which was indicated by reduced force production, fatigue resis

162 RPE dedifferentiation was indicated by reduced pigmentation, altered cellular

163 Deficits in central neurosteroid production were indicated by reduced 5alpha-reductase mRNA levels i

164 airwise additivity of the hydrophobic effect is indicated by reliable experimental Henry's constants

165 e different regions between local alignments are indicated by reporting only similar regions.

166 nthesis of VirF and its downstream effectors was indicated by restoration of invasion when a mutation

167 An important role for these cTnT sites is indicated by results demonstrating that ROCK-II induc

168 cade is relevant to asthmatic hypersecretion was indicated by results showing that mucin induction by

169 Pathophysiological significance of VEGF-Ax is indicated by robust expression in multiple human tiss

170 Endocardial contact is indicated by S-T segment elevation.

171 nectivity in the ventral and dorsal striatum was indicated by seed-based analyses on resting-state da

172 tional importance of bidirectional promoters is indicated by selective pressure to maintain the arran

173 components in control of cell growth in WI38 is indicated by several lines of evidence.

174 Tumor-selective replication is indicated by several lines of evidence.

175 This was indicated by significantly increased nuclear translo

176 timated cell number in the adult hippocampus was indicated by simple regression analyses.

177 ia-mediated apoptosis induced by survivin-2B was indicated by Smac release from mitochondria, activat

178 ctions between cells and the mineral surface were indicated by sorption and pH-induced desorption res

179 likely being mediators in electron transfer, was indicated by specific inhibition of their activity t

180 ng complexes at saturating levels of 2 and 4 is indicated by splitting of the backbone NH resonances

181 jury induced significant liver damage, which was indicated by striking levels of apoptosis.

182 Convergence of the calculated free energies was indicated by substantial declines in standard deviat

183 al significance of scale-free brain activity is indicated by task performance modulation and regional

184 expression between zebrafish and mouse teeth are indicated by the apparent lack of fgf8 and pax9 expr

185 dazole, two separate pathways of heme access are indicated by the distinct kinetics at low and high c

186 n and compensatory insertion/deletion events are indicated by the failure of mutations to affect seco

187 requirement of Wg signaling for the process are indicated by the finding that mislocated RP2 neurons

188 Very large connectivity effects are indicated by the results of experiments testing how

189 the gene is unclear; horizontal transfer may be indicated by the similarity of the tRNA domain to tha

190 athways related to the SLE pathogenesis have been indicated by the identified genetic risk factors, i

191 A developmental role for the Ahr locus has been indicated by the observation that mice harboring a

192 d trial, our results are more uncertain than is indicated by the 95% CI.

193 This role is indicated by the ability of altered Smo proteins to p

194 ding protein (C/EBP) family in myeloid cells is indicated by the ability of C/EBPbeta to replace C/EB

195 However, a peripheral site of action is indicated by the ability of intravenous CGRP to trigg

196 This is indicated by the CD200-deficient mouse model, in whic

197 educes the baseline inflammatory status that is indicated by the CRP concentration in healthy adult b

198 een confined to the last 4 million years, as is indicated by the dating of intact retroelements.

199 e relevance of these studies to human cancer is indicated by the demonstration that: (a) activation o

200 The presence of sulfotyrosine is indicated by the detection of free tyrosine after tan

201 lowed cooling responsible for CM enhancement is indicated by the development of shell-related emissio

202 ctive site, and is the site of the mutation, is indicated by the disappearance in the F50A mutant of

203 The use of these intervals, which is indicated by the documents in the Dresden Codex, perm

204 for Runx function in the senescence program is indicated by the effects of Runx2 disruption, which r

205 acids; instead, it is related to flux, which is indicated by the enzymatic capacity to use these cent

206 ortance of this relatively small pool of TAG is indicated by the fact that cardiac mechanical functio

207 al role for the apical localization of ErbB2 is indicated by the fact that ErbB2 phosphorylated at ty

208 Target specificity is indicated by the fact that these metal chelate inhibi

209 ional significance of CD40 ligand clustering is indicated by the finding that clustering of CD40 on B

210 nvolvement of this lysine in proton transfer is indicated by the finding that its substitution with a

211 The specificity of this effect is indicated by the finding that WNK4 and the carboxyl t

212 ation of COX-2 expression in the vasculature is indicated by the findings that the expression of COX-

213 EMT processes induced by EtDO-P4 or TGF-beta is indicated by the following findings: (i) The enhanced

214 angement of the bases in Rh2(DTolF)2{d(ApA)} is indicated by the H8/H8 NOE cross-peaks in the 2D ROES

215 The sensitivity of our analyses is indicated by the high coverage of membrane proteins.

216 The effectiveness of this screening is indicated by the identification of eight new target o

217 High avidity is indicated by the independence of cytolysis from CD8/M

218 dissociation at the transition state of TadA is indicated by the large [6-(15)N] KIE of 1.022 and cor

219 e ribose 2'-OH and alpha-P in enzyme binding is indicated by the loss of productive binding seen with

220 at task-shifting is far more widespread than is indicated by the medical literature.

221 Early formation of the pyrite is indicated by the mineralogical composition of iron, s

222 Its critical role is indicated by the multitiered regulatory mechanisms th

223 Absence of a multivariate dependence is indicated by the null model being the most likely.

224 The clinical relevance of the data is indicated by the observation of decreased expression

225 Functional involvement of COX-1 is indicated by the observation that central, but not sy

226 pecific ketonization of an enol(ate) species is indicated by the observation that COMC-6 (chirally la

227 A high level of specificity is indicated by the observation that DDAB binding is dep

228 upport for a more significant role for GNA-3 is indicated by the observation that expression of a GTP

229 The clinical significance of these findings is indicated by the observation that the BRCA2/APRIN int

230 nism through which SP may promote plasticity is indicated by the observations that STIM-1, the sensor

231 Cooperativity is indicated by the peptide sampling either the coiled s

232 nic potential of many Gram-negative bacteria is indicated by the possession of a specialized type III

233 depletion of the proton motive force, which is indicated by the potential-sensitive dye bis-(1,3-dib

234 S, an increase in alpha-helical conformation is indicated by the predominant Raman amide I marker ban

235 wastewater sludge retention pond in Magnolia is indicated by the presence of congeners that had not b

236 Coherent random lasing is indicated by the presence of narrow peaks rising out

237 Kidney damage is frequently asymptomatic but is indicated by the presence of proteinuria, hematuria,

238 s, but their existence in sexual populations is indicated by the presence of sperm in the reproductiv

239 RI, active inflammation of sacroiliac joints is indicated by the presence of subchondral bone marrow

240 gene expression while a core function of EWG is indicated by the regulation of metabolic genes by bot

241 nd impaired basal ganglia-dependent behavior is indicated by the reversal of behavioral deficits thro

242 o the regulation of cellular DNA replication is indicated by the transient translocation in heated ce

243 ction in rsw4 at the restrictive temperature is indicated by the widespread failure of replicated chr

244 nt hypoventilation during the fentanyl trial was indicated by the 9% lower V(E)/V(CO(2)), causing a 5

245 e importance of the VEGF receptor neuropilin was indicated by the ability of a neuropilin-binding VEG

246 hway in GM-CSF-stimulated delay of apoptosis was indicated by the ability of LY294002 to attenuate ap

247 role for p53 in TRAIL-R2-mediated apoptosis was indicated by the ability of p53 siRNA to significant

248 bacterial genomic DNA, and high specificity was indicated by the absence of reactivity against close

249 This was indicated by the absence of the adjuvant effect in v

250 oordination of Pro and redox metabolism also was indicated by the altered expression of chloroplast a

251 able benefit when the location of the target was indicated by the appearance of a brief peripheral pr

252 shown to involve a radical mechanism, which was indicated by the appearance of an induction period w

253 A role for NK cells was indicated by the complete abrogation of systemic tum

254 sosomal clearance of alpha-synuclein in vivo was indicated by the detection of alpha-synuclein in the

255 The efficacy of IP-10 depletion was indicated by the effective abrogation of scIL-12-med

256 Functional redundancy among the three mtACPs was indicated by the embryo-lethal phenotype associated

257 tion-competent HIV-1 in thy/liv-SCID-hu mice was indicated by the emergence of HIV-1 infection in mic

258 ective pressure for increased tmRNA activity was indicated by the emergence of mutant strains with el

259 oxidase in LT-induced microbicidal activity was indicated by the fact that bacterial killing was abr

260 ved in the control of cAMP levels in oocytes was indicated by the finding that expression of the mRNA

261 emporal role for cAMP in biofilm development was indicated by the finding that glucose addition after

262 This was indicated by the following: 1) the increase in [Ca2+

263 Sleep-disordered breathing was indicated by the frequency of apnea and hypopnea eve

264 electrochemical oxidation of adenine, which was indicated by the improvement of anodic peak current

265 a much milder increase in proliferation than was indicated by the in vitro experiments.

266 for these immune cells in tumor suppression was indicated by the inability of rIL-7/HGFbeta to inhib

267 e outcome of EMT, was abolished by TSA; this was indicated by the inhibition of type I collagen depos

268 Microbial methanogenesis was indicated by the isotopic compositions of methane an

269 This was indicated by the lack of anti-Gal immunoglobulin G (

270 henever OCT was performed, foveal hypoplasia was indicated by the lack of foveal dip.

271 This was indicated by the lack of protection from cleavage at

272 The specificity of the findings was indicated by the lack of these effects in leptin-def

273 The very good precision was indicated by the low relative standard errors for th

274 ted a higher acyl chain packing order, which was indicated by the lower acyl chain packing free volum

275 ficance of Bim in this GrB apoptotic cascade was indicated by the marked protection against GrB-media

276 n could be relevant to postharvest infection was indicated by the observation that C. gloeosporioides

277 The importance of FoxM1 to cell fate was indicated by the observation that G2/M arrest follow

278 The clinical relevance of the data was indicated by the observation that lung tissue from p

279 Subjective unsteadiness was indicated by the patients on a four-point scale usin

280 mia virus (MuLV) Env protein in viral fusion was indicated by the potent inhibition of MuLV-induced f

281 The presence of this mechanism was indicated by the presence of these alternate product

282 CCR2 in upregulating costimulatory molecules was indicated by the reduced expression of CD80, CD86, a

283 The selectivity was indicated by the regularisation of clotting by lipop

284 lation in enhancing the fitness of R. rubrum was indicated by the relationship between PHA content an

285 Goodness of fit was indicated by the residual standard deviation.

286 t complex, and direct, pairwise interactions were indicated by the in vivo test in yeast.

287 50 ml of milk and 6 to 41,111 PFU/g of feces were indicated by the PMS-phage assay.

288 he three dominant forms of the fibrils which were indicated by the presence of three distinct, self-c

289 y motor phenotypes observed in these mutants is indicated by their altered sensitivity to the dopamin

290 matory state of patients with hyperlipidemia is indicated by their increased erythrocyte sedimentatio

291 Their ecological novelty is indicated by their unique dental proportions, and by

292 ficity of these antagonists for MC receptors was indicated by their lack of effect on l-Glu responses

293 cond, specific activation of dendritic cells was indicated by their marked up-regulation in expressio

294 ic peaks containing FP-biotinylated peptides were indicated by these diagnostic ions.

295 ubscale, c) the need for the fifth construct is indicated by this study's results, and d) including t

296 A possible triple-strain infection was indicated by three different T4 sequences in culture

297 in which the expression of orthologous pairs is indicated by two points.

298 or a potential structural variant at a locus is indicated by variation in the counts of short-reads t

299 or activities, but functional specialization was indicated by YqjG and SpoIIIJ showing respectively g

300 organization in response to interneuron loss was indicated by zinc transporter-3 (ZnT3)-- and beta-sy