ライフサイエンスコーパス: be key to

1 These findings are key to a more complete understanding of PDGF ligand-

2 E STATEMENT Direction selective (DS) neurons are key to a variety of visual behaviors including, targ

3 gies of aromatic molecules with substituents is key to a variety of chemical and material application

4 Brownian escape is key to a wealth of physico-chemical processes, includ

5 ountries with a low incidence of the disease is key to accelerate progress towards its elimination.

6 large protein family are targeted by a drug is key to achieving a desired therapeutic response.

7 The inclusion of several biomes is key to achieving multiple benefits.

8 ise control over the energies of these sites is key to achieving novel reaction pathways with superio

9 he development of more productive crops will be key to addressing the challenges that climate change,

10 Interdisciplinary collaborations will be key to advance beyond simple correlative analyses in

11 the highly unstable fluoroiodomethyllithium was key to allowing rapid 1,2-migration over competing d

12 isualization of these differences that could be key to an understanding of a proteins' function.

13 erred from male to female during copulation, is key to An. gambiae reproductive success as it license

14 is previously unappreciated tyrosine residue is key to anchoring the intercalating loop and stabilizi

15 Tracing the lineage history of cells is key to answering diverse and fundamental questions in

16 ctivation of the 3,5-dinitrobenzyl analogues is key to antimycobacterial activity.

17 ssessing and understanding these differences is key to appreciating metabolic diversity, and to attem

18 ighly heterogeneous, and severity evaluation is key to asthma management.

19 this unique set of miRNA-target pairs could be key to attenuate the expression of several transcript

20 the favorable discharge of Ni(3+) to Ni(2+) are key to beta-NiOOH's OER activity.

21 stablishing strong membrane potential, which is key to biofilm matrix production.

22 metal-organic-framework (MOF) nanoparticles is key to biomedical applications and seeding techniques

23 ect indicator of condensate liquidity, which is key to both cellular functions and diseases.

24 Phosphodiesterase-6 (PDE6) is key to both phototransduction and health of rods and

25 discrete from the interdimer interface that is key to cage assembly.

26 p actuation and readout of mechanical motion is key to characterize mechanical resonators and exploit

27 th structural and dynamic information, which is key to connecting intermediates and to understanding

28 he encounter dynamics experienced by animals is key to connecting the empirical work to the idealized

29 , and timely livestock vaccination appear to be key to controlling RVF in this setting.

30 Cultural norms are key to cooperation in human societies.

31 the molecular underpinnings of this decline is key to counteract age-related disease.

32 We propose that NOTCH1 signaling is key to CRC progression and should be exploited clinic

33 ion of phospholipids from the outer leaflet, is key to creating an almost impenetrable barrier to hyd

34 Genetic diversity is key to crop improvement.

35 trictions, isolation of infected individuals is key to curtailing transmission.

36 Antibodies are key to cutaneous host defense and inflammation.

37 mechanism of the function of these complexes is key to decoding synaptic modulation and their global

38 mpartments; this tunable branching mechanism is key to define and diversify dendrite arbor compartmen

39 CMV serostatus and age at vaccination, will be key to defining CMV vaccination strategies.

40 ulatory mechanisms during tissue homeostasis is key to delineating their roles in development and reg

41 nning the architecture of the heterogeneity, are keys to delivering mechanism-based stratified treatm

42 and racemization on asteroidal parent bodies is key to demonstrating how amino acids evolved to be mo

43 he dynamics of person-to-person transmission is key to designing effective interventions.

44 ale continuous crop monitoring systems (CMS) are key to detect and manage agricultural production ano

45 Knowing how to interpret them is key to detecting or ruling out complications.

46 Changes in marine primary productivity are key to determine how climate change might impact mar

47 On the other hand, the contacts which are key to determining progression from the intermediate

48 that assessments across multiple generations are key to determining the full magnitude of adverse eff

49 Our data show that Rac1 and cofilin activity are key to determining the rate of acquisition of alcoho

50 ontent is reduced, and the C-terminal domain is key to determining agonist response in vivo.

51 derstanding how embryo-uterine communication is key to determining an optimal implantation site neces

52 Quantifying morphological evolution is key to determining the patterns and processes underly

53 ation structure and rates of diversification is key to determining the role of pollen dispersal on pl

54 e results of studies like that reported here are key to developing an understanding of the impact of

55 interactions critical for brain health will be key to developing effective therapies for dementia.

56 ter understanding of host protective factors is key to developing an effective remedy.

57 Such information is key to developing global and context-specific health

58 haPD-1/PD-L1 immune-checkpoint immunotherapy is key to developing new treatment strategies.

59 ollection and analysis of health information is key to developing population-specific clinical guidel

60 Understanding the mechanisms of fibrillation is key to developing rational mitigation strategies.

61 Manually annotated data is key to developing text-mining and information-extract

62 Cell fate transitions are key to development and homeostasis.

63 antiomeric excess (e.e.) in chiral compounds is key to development of chiral catalyst auxiliaries and

64 Ns to skin and systemic disease pathogenesis is key to development of new therapeutics and improved p

65 ecies and defining their role(s) in assembly is key to devising new routes to control disease.

66 reactive, information on trafficking routes is key to disrupting trade and curtailing wildlife crime

67 in a diversity of microscopic organisms that are key to ecosystem function, including fungi, protists

68 he largest anthropogenic CO(2) emissions and are key to effective emission reduction strategies.

69 these viruses evolve in their natural hosts is key to effective control strategies.

70 ence and roles in shaping microbial fitness, is key to elucidating how the incredible diversity of th

71 d, the engagement of goal-directed attention is key to enable rule generalization.

72 Cooperative Ca(2+) binding is key to enable this exchanger to efficiently respond t

73 astic collisions involving molecular species are key to energy transfer in gaseous environments.

74 ding blocks, such as molecules and proteins, is key to engineering functional materials with predesig

75 Community-led sanitation programs could be key to ensuring healthy household environments and re

76 e number of high-risk people testing for HIV is key to ensuring prompt treatment and preventing onwar

77 her migrant populations in the United States is key to ensuring successful resettlement.

78 table for infants, children, and adolescents is key to ensuring that global HIV treatment targets can

79 hite felt for both the cathode and the anode was key to ensuring chemoselectivity and high deuterium

80 alongside existing vector control strategies is key to eradicating malaria in the near future.

81 on of cell-type-specific regulatory networks is key to establish a causal link between genetic variat

82 her feature of this methodology, which could be key to expand the current understanding of autophagy

83 ce generator can bind only one microtubule), is key to explaining the dynamics of spindle positioning

84 these NA responses during natural infection is key to exploiting these properties for improving infl

85 nd overcame an apparent transmission paradox is key to finally eliminating HAT.

86 Knowledge about migration potential is key to forecasting species distributions in changing

87 ss that effective cross-disciplinary efforts are key to forward progress in the field.

88 ulative solid sulfur and lithium sulfide and are key to full exertion of the high-energy-density Li-S

89 with exposure and response to treatment will be key to further improve treatment strategies.

90 This study is key to further analyze the properties of fungal biolu

91 well established that binding of HR1 and HR2 is key to fusing viral and cellular membranes.

92 study suggest that damage feedback processes are key to future ice shelf stability, grounding line re

93 Appropriate correction of aphakia is key to good outcomes.

94 g of Muller glia into neurogenic progenitors is key to harnessing the regenerative potential of the r

95 Widespread testing and infection control are key to help prevent COVID-19 morbidity and mortality

96 of the o-nitrobenzyl scaffold of the linker is key to high yields and compatibility with the AGA wor

97 on of T cells and the generation of antibody are key to immunotherapy response and propose a new biom

98 the proportion who become ill by risk group is key to implementing prevention measures.

99 ng up functional databases for pathogenicity is key to implementing these approaches.

100 se rates to various classes of immunotherapy is key to improving efficacy and controlling these adver

101 ng-term glacier response to external forcing is key to improving projections.

102 Addressing existing barriers is key to improving uptake.

103 ype 1 (HIV-1) to transduce nondividing cells is key to infecting terminally differentiated macrophage

104 Although disinfection is key to infection control, the colonization patterns a

105 ergence of new body plans or metabolism, and is key to inferring the origin of new genes, detecting m

106 d residues, evolutionarily variable residues are key to initial JDP/Hsp70 recognition-via electrostat

107 e mere existence of physiological synchrony, are key to interpreting physiological synchrony as a soc

108 wever, dynamic properties of the microtubule are key to its function, and this behavior has proved di

109 etween the Cu(I) and Cu(II) oxidation states being key to its speciation, bioavailability, and toxici

110 port, and metabolize a wide range of glycans is key to its virulence.

111 ts of dominant species on their environments are key to linking patterns of diversity to ecosystem fu

112 Improving air quality may therefore be key to lowering the neonatal jaundice risk.

113 results demonstrate that migrant hoverflies are key to maintaining essential ecosystem services.

114 dent feedbacks, mediated by natural enemies, are key to maintaining the high diversity of tree specie

115 sing prolyl hydroxylase domain (PHD) enzymes are key to maintaining tissue homeostasis during hypoxia

116 at a balanced regulation of granule turnover is key to maintaining beta cell function and diabetes pr

117 organs and whole organisms, nutrient sensing is key to maintaining homeostasis and adapting to a fluc

118 predict that this rescued detachment pathway is key to maintaining kinesin processivity under load.

119 Clathrin-mediated endocytosis (CME) is key to maintaining the transmembrane protein composit

120 We propose that BAIAP2L2 is key to maintenance of the normal actin structure of t

121 This process of gametogenesis, which is key to malaria transmission, involves extensive membr

122 the underlying causes of pathogen emergence is key to managing the impact of EPPs.

123 arallel sequencing (MPS) of genetic variants is key to many areas of science and medicine, such as ca

124 variant proportions using PCR amplification is key to many genetic studies, including studying tumor

125 Probing individual chemical reactions is key to mapping reaction pathways.

126 A well designed transition service is key to maximising potential for these patients, and s

127 stabilize, early training interventions may be key to maximize the system's potential for recovery.

128 he system of care to reduce treatment delays is key to maximizing the benefits of reperfusion therapi

129 uences the use of resilience mechanisms that are key to mental health outcomes in the face of adversi

130 ow that incorporating realistic vasculatures is key to modelling the contrasting fluid dynamic respon

131 Results indicate that pH and particle ratios are key to modulating the stability of MoS(2)/clay syste

132 Measurement of total protein in urine is key to monitoring kidney health in diabetes.

133 Understanding and controlling disorder is key to nanotechnology and materials science.

134 ted induction, but also repression, of genes are key to normal differentiation.

135 g at endplates, known as terminal sprouting, is key to normal muscle fiber reinnervation following ne

136 rought at both individual and species levels is key to ongoing forest management and preparation for

137 ated to diminishing decision-making capacity is key to optimize advance care planning for people with

138 synthetic pathways for these polysaccharides is key to our ability to design vaccines and other preve

139 tant molecular events at a microscopic level is key to our understanding of membrane transport, yet c

140 Controlling crystallization kinetics is key to overcome the temperature-time dilemma in phase

141 g a better understanding of these mechanisms is key to overcoming the challenges associated with vacc

142 during responses to microbial infections and are key to pathogen clearance and control.

143 electrical signals within cortical networks is key to perception and cognitive function.

144 nslocated animals, behavioral competence may be key to post-release survival.

145 escales much shorter than the coherence time is key to powerful quantum simulation and computation.

146 anding root decomposition with global change is key to predict carbon (C) and nutrient dynamics on th

147 rs governing global patterns of biodiversity are key to predicting community responses to ongoing and

148 ut the last several decades, vaccination has been key to prevent and eradicate infectious diseases.

149 ue preparation of calcified coronary lesions is key to prevent stent failure.

150 r Shannon entropy in RRE stem-loop II, which is key to primary Rev binding.IMPORTANCE HIV-1 replicati

151 Pest risk analysis (PRA) is key to prioritize agricultural biosecurity efforts, b

152 various histone/protein deacetylases (HDAC) are key to promoting Treg-based immunotherapy.

153 re sensors within microfluidic architectures is key to providing advanced sample processing capabilit

154 This rigidity is key to rationalizing the protection toward aggregatio

155 o affordable medicines in all countries will be key to reach hepatitis elimination.

156 Prevention is key to reduce the number of suicide deaths and preven

157 priate intensification of diabetes treatment are key to reducing disparities in downstream vascular o

158 yopia onset and slowing its progression will be key to reducing the rapid rise in its global prevalen

159 design of better superalloys, a quest which is key to reducing CO(2) emissions in air-traffic.

160 addressing gender and social norms, however, is key to reducing stigma and meeting the demand for con

161 health approach to prevention and treatment is key to reducing the harms of firearm violence.

162 intensification of glucose-lowering therapy is key to reducing the risk of major vascular outcomes.

163 Turbulent mixing in the ocean is key to regulate the transport of heat, freshwater and

164 density functional theory (DFT) predictions, are key to reliably assigning the Cp*( exo/ endo-eta(4)-

165 Supporting documentation is key to render a package accessible for users.

166 The oxygen evolution reaction (OER) is key to renewable energy technologies such as water el

167 OM) and eastern (Mediterranean) populations, is key to resolving the current status of the Atlantic b

168 s to alleviate microvascular rarefaction may be key to restoring exercise tolerance.

169 g workforce, employee flexibility and choice are key to retention and wellbeing.

170 l concepts include the idea that neutrophils are key to revascularization and subsequently reverse-tr

171 Our systems analysis of Rho regulators is key to revealing emergent organization principles of

172 y block all binding sites of a target lectin is key to robust inhibition of viral infection.

173 eneration and afferent nerve activity, which are key to sensing bladder fullness.

174 whether lack of antigenic recognition might be key to shifting cells from contributing to an aggress

175 sequence editing rather than deglycosylation is key to SKN-1A function.

176 Residues within this footprint are key to stabilizing the pre-fusion spike.

177 Primary prophylaxis is key to stemming this burgeoning problem and its assoc

178 Cancer phylogenies are key to studying tumorigenesis and have clinical impl

179 identification of sites of RNA modification is key to studying the functional role of such modificat

180 Policies and programs that were key to stunting decline focused on promoting rural

181 where the dynamics of tumor and immune cells is key to success.

182 iciency in mitotic rounding, a process which is key to successful cytokinesis.

183 he degree to which species can rapidly adapt is key to survival in the face of climatic and other ant

184 and responding promptly to external stimuli is key to survival(14-19).

185 cord of past environmental change, which can be key to surviving the future.

186 umor cells, the YAP/TAZ-autophagy connection is key to sustain transformed traits and for acquisition

187 lts suggest that optimising P fertiliser use is key to sustainable intensification of agricultural sy

188 sed microtubule (MT) density and MT assembly was key to sustaining stretch-growth, suggesting a possi

189 ductivity of metal-organic frameworks (MOFs) is key to synergizing their attractive synthetic control

190 Protein-DNA interactions are key to the functionality and stability of the genome

191 nely tuned, moderately coupled nuclear spins are key to the hyperpolarization process, which makes th

192 d electron flux of the cyclic redox reaction are key to the layer-to-tunnel structure transformation

193 Pericytes are key to the maturity of these vascular networks, and

194 microsecond time scale after photoexcitation are key to the photocathode behavior observed for defect

195 d properties of colloidal metal nanocrystals are key to the realization of their vast applications.

196 ge bodies of peptide-MHC-II interaction data are key to the solution of this problem, a solution that

197 orrelations in interacting many-body systems are key to the study of quantum matter.

198 ed C-terminus such as a C-terminal thioester are key to the synthesis of larger proteins via expresse

199 han simply the presence of compatible fungi, are key to the understanding of plant invasion processes

200 Patient stratification methods are key to the vision of precision medicine.

201 As direct causations are keys to the fundamental underpinnings of a variety o

202 of IL-23 pathways and bile acid pathways may be key to the development of WD-associated psoriasiform

203 This equilibrium was shown to be key to the reactivity of the Ir(III)-H; 2 equiv of [1

204 the sense of the internal state of the body, is key to the adaptive regulation of our physiological n

205 ized for controlling Ae. aegypti populations is key to the development of more effective mosquito con

206 the interplay between these genetic factors is key to the discovery of new biomarkers and treatments

207 ience with conflicts, alongside cooperation, is key to the emergence and development of moral obligat

208 blem of fundamental biophysical interest and is key to the emergence of several phenomena of biologic

209 cerous tissues with engineered nanoparticles is key to the future success of cancer nanomedicines in

210 n of older people to stay healthy for longer is key to the future sustainability of health, social an

211 ticular DCL member and a given effector that is key to the information processing, but the change in

212 The control of molecules is key to the investigation of quantum phases, in which

213 onstrates that the interface described above is key to the mechanical stability of helical membrane t

214 e centrosome, suggesting that this organelle is key to the mechanism of posterior predominant LIS.

215 The formation of self-organized patterns is key to the morphogenesis of multicellular organisms,

216 Regulated gene expression is key to the orchestrated progression of the cell cycle

217 ic barriers opposing interspecific gene flow is key to the origin of new species.

218 ate how adherence to Open Science principles is key to the OTN community and outline five activities

219 reases the surface area for gas-exchange and is key to the physiological function of the lung.

220 erated by basic residues surrounding Phe-232 is key to the polarization of the PS2 moiety.

221 that the divergence through sublocalization is key to the retention of paralogous cpAPX genes in ang

222 -loading complex, the peptide editor tapasin is key to the selection of MHC-I-bound peptides.

223 e versus proportionate mitral regurgitation) is key to the success of new devices.

224 Assessment of protein stability and function is key to the understanding of biological systems and pl

225 Understanding and correcting these offsets is key to the well-defined calendar placement of a Middl

226 es of the unbiased approach developed, which was key to the identification of high-affinity antibodie

227 ptide concentrations consequently appears to be key to their synergistic dye-releasing activity from

228 he hallmark of angiosperms and its evolution is key to their diversification.

229 How these cells interact in space and time is key to their ecology and evolution.

230 rching for resources such as food by animals is key to their survival.

231 etric amounts of Ti(OiPr)(4) in HFIP solvent are key to this reactivity, and the method tolerates a b

232 nd that longevity of anti-Env antibodies may be key to this protection.

233 hat the hippocampal theta rhythm (4 to 8 Hz) is key to this mapping function, as it has been repeated

234 The fossil record is key to this problem, as it provides data on repetitiv

235 mple, commercially available ligand, PAd(3), is key to this water-assisted mechanism by promoting coo

236 repair and replacement of blood vessels have been key to treating acute injuries, as well as chronic

237 This is key to trigger the simultaneous ignition of the catal

238 dence that systemic uptake of food allergens is key to triggering anaphylaxis.

239 Nonlinear susceptibilities are key to ultrafast lightwave driven optoelectronics, a

240 cales contribute to tissue form and function is key to uncovering the mechanisms driving animal devel

241 ay mask fine-scale ecological responses that are key to understand ecosystem functioning and resilien

242 Rewards are key to understand people's choices and decisions.

243 on-arrested ribosome nascent chain complexes is key to understand co-translational folding.

244 Knowledge of the entry receptor is key to understand SARS-CoV-2 tropism, transmission an

245 Evolutionary responses to nutrition are key to understanding host shifts and the resulting p

246 mical arrest and heterotypic buffering, that are key to understanding how pathological phase transiti

247 oducible immune competent preclinical models are key to understanding mechanisms of action, interacti

248 Grid integration studies are key to understanding our ability to integrate variab

249 These findings are key to understanding squamous epithelial homeostasis

250 legacies of both the recent and ancient past are key to understanding the forces shaping global patte

251 The genomes of non-bilaterian metazoans are key to understanding the molecular basis of early an

252 s that pattern and maintain dendritic arbors are key to understanding the principles that govern nerv

253 Transcriptomes are key to understanding the relationship between genoty

254 cal effects between plants and microclimates are key to understanding the response of forest biodiver

255 e sister groups of all other winged insects, are key to understanding this radiation.

256 l fingerprint of environmental adversity may be key to understanding health and disease, as it encomp

257 Neural systems implicated in reward could be key to understanding how food advertising drives food

258 he cellular hallmarks of normal ageing might be key to understanding the events that convert normal a

259 tional analysis of protein structure and may be key to understanding their utility for different prob

260 hich organisms compete for limited resources is key to understanding behavioural and social evolution

261 he function of different neuronal cell types is key to understanding brain function.

262 molecules such as proteins and nucleic acids is key to understanding cellular life on the molecular s

263 acute respiratory coronavirus 2 (SARS-CoV-2) is key to understanding disease pathogenesis, but few st

264 one post-translational modifications (hPTMs) is key to understanding fundamental epigenetic regulator

265 , identification of TF binding sites (TFBSs) is key to understanding gene expression and whole regula

266 on arose with respect to non-avian dinosaurs is key to understanding how birds achieved their remarka

267 porally resolving GPCR transduction pathways is key to understanding how cell signaling occurs.

268 ing nascent macromolecular synthesis in vivo is key to understanding how cells and tissues progress t

269 ments for efficient oxygen (O(2)) activation is key to understanding how enzymes maintain efficacy an

270 f adaptive evolution among different species is key to understanding how evolution works.

271 Mapping their distribution is key to understanding how his paintings have changed w

272 age relationships among different cell types is key to understanding human brain development.

273 tructing the physiology of extinct organisms is key to understanding mechanisms of selective extincti

274 fire disturbance, human agency, and climate is key to understanding rapid population declines of fir

275 derstanding secondary cell wall architecture is key to understanding recalcitrance i.e. identifying f

276 Perturbation of neuronal activity is key to understanding the brain's functional propertie

277 eads to the generation of force and movement is key to understanding the cellular roles that these mo

278 ater-soluble species from asphaltene samples is key to understanding the contribution of photochemica

279 ppearance of modern humans in a given region is key to understanding the dispersal process and the re

280 nding the challenges faced by social animals is key to understanding the evolution of cognition.

281 ctions, and conservation, as presented here, is key to understanding the impact of mutations in evolu

282 bon pool, constraining sources of marine DBC is key to understanding the long-term persistence of car

283 rated and how acoustic signals are perceived is key to understanding the neurobiology of social behav

284 state of an individual ('deep phenotyping') is key to understanding the prevention, initiation, prog

285 ecular profiles of a tumour during treatment is key to understanding the recurrence mechanisms and de

286 Solving how this network is regulated is key to understanding the underlying mechanisms of tum

287 les, and resolving the drivers of aerosol pH is key to understanding their environmental effects.

288 location and dynamics of RNAs in live cells is key to understanding their function.

289 g lncRNA expression across cells and tissues is key to understanding their role in determining phenot

290 Knowledge of their community dynamics is key to understanding their role in marine food webs a

291 roteome changes over the course of infection is key to understanding this host-virus interplay.

292 ciated characteristic of prion variants that is key to understanding transitions between prion states

293 derstanding interspecific viral transmission is key to understanding viral ecology and evolution, dis

294 ineates the boundaries of phase co-existence is key to understanding whether LLPS is an equilibrium o

295 e cross-linking of collagen changes with age is key to understanding why the mechanical properties of

296 e precursor reactivities were elucidated and were key to understanding the final reaction conditions.

297 ine learning models and segregation database are key to unlocking the full potential of GB segregatio

298 intentional introduction of economic plants is key to unravelling drivers of plant naturalization.

299 mental chemistry of these homoatomic species is key to unravelling their behaviour in a broad variety

300 otic stress tolerance under field conditions is key to varietal crop improvement in the face of clima