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2 grate PC alongside restorative surgical care are limited by a lack of surgical quality indicators to
3 have improved over the years, further gains are limited by a seemingly zero-sum relationship between
4 ic repeats (CRISPR)-based genome editing can be limited by a lack of compatible protospacer adjacent
5 evolution in response to climate change will be limited by a lack of heritable variation within north
6 uality distal associations (trans-eQTLs) has been limited by a heavy multiple testing burden and the
7 ical significance, studies on AspH have long been limited by a lack of assays for its isolated form.
8 lity, particularly for these procedures, has been limited by a lack of definitional clarity and their
10 dence for the claim that cerebral processing is limited by a constant energy supply, which thus requi
11 d 8 key acute stroke impairments, this study is limited by a focus on physical impairments, although
12 ts with triple-negative breast cancer (TNBC) is limited by a lack of effective molecular therapies ta
13 olds promise for cardiovascular medicine but is limited by a lack of large, heterogeneous and granula
14 echanistic understanding of these toxicities is limited by a lack of suitable immunocompetent preclin
15 of gadolinium-based contrast agents (GBCAs) is limited by a lack of understanding of the relationshi
18 860 +/- 160 kilotonnes of nitrogen per year) is limited by a spatial disconnect between high-density
20 Delivery via adeno-associated viruses (AAVs) is limited by AAV packaging capacity, which precludes th
23 and their potential value to plant breeding are limited by an incomplete picture of sRNA variation b
24 ession of malignancies, immunotherapies have been limited by an immunosuppressive tumor microenvironm
25 due to endemic infections have historically been limited by an inability to directly observe wildlif
28 Clinical use of human IL-10 (hIL-10) has been limited by anemia and thrombocytopenia following sy
33 terior wall (LAPW) may improve outcomes, but is limited by both the difficulty of achieving lesion du
35 as medical tools, clinical applications have been limited by certain characteristics of phage biology
36 unts of type I interferon (IFN), which could be limited by CGAS or STING knockdown, mitochondrial DNA
37 ess of pathogen detection by T cell receptor is limited by chemical similarity of foreign and self-pe
39 Currently available software for this task is limited by computational efficiency, variant support
42 el transitions rely on bulk rheometry, which is limited by contact with the sample, or microrheologic
43 oretical models predict that information may be limited by correlated noise in large neural populatio
46 g of the safety and efficacy of cannabis has been limited by decades of worldwide illegality and cont
47 ergy-density battery anode material, its use is limited by dendrite formation and associated safety r
48 ication of bio-templated metallic structures is limited by differences in properties, processing cond
49 he impact of humans on the natural landscape is limited by difficulties in accurately comparing past
50 uggest that (1) exercise tolerance with COPD is limited by dynamic hyperinflation; and (2) cyclically
51 ficant at 24 weeks, and trial interpretation is limited by early termination and inconsistent finding
52 tion, but current electrophysiological tools are limited by either low spatial resolution or electrom
53 for decades now, but their energy densities are limited by electrode materials and conventional liqu
55 he current platforms for delivery into cells is limited by endosomal entrapment of delivered protein
56 wever, these in-source annotation algorithms are limited by ESI sources that are generally designed t
58 mpal dynamics to memory-guided behaviors has been limited by experiments that lack the temporal resol
59 re herbivores alter community composition or are limited by factors other than food ('resource-contro
60 ing disease conditions, but current vaccines are limited by factors such as a lack of potency and ant
61 wever, the clinical application of NANPs has been limited by factors such as chemical instability, in
62 Closer examination showed that many studies were limited by factors such as imprecise methods to det
64 ated haemopoietic cell transplantation (HCT) is limited by graft-versus-host disease (GVHD), which is
67 of outcomes after pediatric critical illness is limited by heterogeneity in methodology, populations,
68 able methods using PCR or capture probes can be limited by high cost, narrow scope of detection, leng
75 (BOLD) cardiac MRI for myocardial perfusion is limited by inadequate spatial coverage, imaging speed
78 cell transplantation (HSCT) has historically been limited by infrequent marrow biopsies, which increa
79 ng methods for recombination rate estimation are limited by insufficient amounts of informative genet
81 ver, current methods for photon recuperation are limited by insufficient bandwidth or parasitic absor
86 ility of diagnostic testing for COVID-19 has been limited by intermittent shortages of supplies requi
93 assic chronic social defeat stress procedure is limited by its exclusive application to adult male ro
97 y investigated, poly(cyclohexene carbonate), is limited by its low elongation at break and high britt
98 nfidence in predictions of future IOD change is limited by known biases in IOD models(7) and the lack
100 in disease genes, but the diagnostic utility is limited by lack of understanding variant function.
103 ever, current photopolymerization strategies are limited by long reaction times, high light intensiti
105 of kilobase-sized DNA sequences in bacteria are limited by low efficiency, a reliance on recombinati
106 mparing sleeve gastrectomy to gastric bypass are limited by low sample size (in randomized trials) an
107 gas chromatography-mass spectrometry (GC-MS) are limited by low sample throughput and complicated sam
108 rent methods for imaging cellular metabolism are limited by low sensitivities, costs or the use of sp
109 and/or drug treatment; however, most methods are limited by low sensitivity, nonspecificity, and mini
110 of biomolecules in live eukaryotic cells has been limited by low component stability and slow reactio
114 nvolves the fecal immunochemical test, which is limited by low sensitivity for the detection of advan
116 However, the impact of these experiments may be limited by manual, non-standardized, static or qualit
117 cterize, classify, and analyze phenotype has been limited by measurement deficits, computing limitati
119 parability and relevance of this information is limited by methodology or observer subjectivity.
121 f currently available mechanoacids, however, is limited by modest force-free stability or a scissile
122 human organs for patients with organ failure-is limited by molecular incompatibilities between the im
123 tion-induced suppression of inhibition (DSI) was limited by monoacylglycerol lipase (MAGL) but not by
125 dies from insurance-based healthcare systems were limited by narrow selection criteria, failure to ap
126 s can revitalize classes of antibiotics that are limited by naturally arising resistance mechanisms.
130 al cancer therapeutics, but their usefulness is limited by off-target effects, which produce alpha-ma
132 uent export of MeHg to downstream ecosystems is limited by particle settling, binding of MeHg on soil
133 bing refractive correction, but its accuracy is limited by patient's subjective judgment about their
134 rate, and energy delivery in the pericardium is limited by penetration through epicardial fat and cor
136 in T1D and solid-organ transplant recipients are limited by poor T(reg) engraftment without host mani
138 torically played an important role, they can be limited by poor patient compliance, adverse side effe
139 as C. elegans or isolated single cells have been limited by poor sensitivity of existing techniques
140 or psychosis, although its potential utility is limited by poor performance in persons of non-Europea
147 ling, such as chromatin immunoprecipitation, are limited by requirement of TF-specific antibodies and
148 as a method of studying single entities, it is limited by requirement of a catalytically active part
151 ic cancers, but efficacy in solid tumors can be limited by restrictive tumor microenvironments (TMEs)
155 g fewer hours than men, but evidence to date is limited by self-report and a lack of detail regarding
156 season onset, late-season photosynthesis can be limited by several factors and the underlying mechani
157 ay hold therapeutic promise but progress has been limited by several factors, including the lability
159 However, perennial grasses productivity can be limited by severe freezing conditions in some geograp
160 based quantum computing architectures, which are limited by short-range exchange interactions(10).
162 ideal place to screen for AF; however, this is limited by shortages in general practitioner (GP) res
163 hRs, reduces alcohol intake, but its use can be limited by side effects at high therapeutic doses.
164 macotherapy; however, their clinical benefit is limited by side effects and addictive potential.
167 ubstrates by chemical vapor deposition (CVD) is limited by slow lateral growth rates, which result in
169 n a hospital setting, but prior reports have been limited by small data sets, poor data quality, or b
175 Indeed, the performance of NaSn(m)BiTe(m+2) is limited by strong bipolar transport and only exhibits
177 ent of high-density magnetic recording media is limited by superparamagnetism in very small ferromagn
181 synthetic libraries of genetic elements, but are limited by the designability, length, fidelity and s
183 nsducer and the most selective sensing layer are limited by the efficiency of deposition of molecules
184 aging in patients, the clinical applications are limited by the invasive administration and short hal
185 However, efforts to repurpose ribosomes are limited by the lack of complete peptidyl transferase
186 le aspects of cancer immunobiology, but they are limited by the lack of physiological complexity.
189 methods with high spatiotemporal resolution are limited by the potential for laser damage to living
192 ) have been used translationally to date but are limited by the significant differences in timing and
193 neovascular age-related macular degeneration are limited by the time span from death to preservation
196 The generalisability of the findings may be limited by the gender imbalance, high educational att
199 fit of HCV antigen testing for screening may be limited by the risk of missing patients with severe l
200 tch local conditions, but again efficacy may be limited by the speed of change and range of patterns
201 data, but application to epigenetic data has been limited by the computational cost, lack of scalable
202 ory and functional insights, but have so far been limited by the confounding effects of differentiati
203 lin and microtubules to spindle assembly has been limited by the fact that physiologically relevant t
204 o applications in optoelectronic devices has been limited by the fragility of the supramolecular stru
205 unctional characterization of these QTLs has been limited by the heterogeneous cellular composition o
206 broader goal of molecular ON/OFF control has been limited by the inability of existing systems to ach
207 ive tasks like deep neural networks, but has been limited by the inaccurate and unpredictable switchi
208 s in seizure frequency during pregnancy have been limited by the lack of an appropriate nonpregnant c
210 st HIV disease progression, but studies have been limited by the low prevalence of this allele in Nor
211 the population biology of the parasite have been limited by the molecular tools currently available.
213 s of eusociality in these marine shrimps has been limited by the sparse genomic resources in this gen
214 the cell biology of thermophilic archaea has been limited by the technical challenges of imaging at h
215 ng cardiac lineage diversification has often been limited by the unreliability of genetic tracers.
216 offee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity
218 fication of genetic profiles of disease risk is limited by the availability of both comprehensive cli
219 or compound identification, but this utility is limited by the availability of high-quality reference
222 any years in different settings, their value is limited by the challenging chemical properties of hem
223 cillators within macrophages and neutrophils is limited by the chronic inflammatory environment, sugg
224 ydrogen Electrode scale and conclude that it is limited by the CO[Formula: see text] adsorption step.
228 heir exact functions in cellular homeostasis is limited by the difficulty of monitoring their activit
233 MX(3) (where M is a metal and X is a halide) is limited by the geometric Goldschmidt tolerance factor
234 ity of state of the art microfluidic systems is limited by the high bead concentrations required for
235 nization (CDI) with porous carbon electrodes is limited by the high ionic resistance of the macropore
236 hods, but their uptake in cartilage research is limited by the highly specialised training required a
238 udy of bacterial interactions within oysters is limited by the inability to promote high-level uptake
239 However, the benefit of these oral agents is limited by the increased risk of bleeding associated
240 Photosynthetic CO(2) fixation in plants is limited by the inefficiency of the CO(2)-assimilating
241 of nitrogen-containing solid-state materials is limited by the inert and gaseous nature of N(2).
242 of the factors that favor efficient excision is limited by the lack of a rapid, accurate measurement
243 ctive hydroxide exchange membrane fuel cells is limited by the lack of high-performance and low-cost
246 al of drug discovery targeting this receptor is limited by the lack of structural information of VIP1
247 s a promising approach to cancer therapy but is limited by the lack of tumor-homing capability of the
249 antity of available data, while its adoption is limited by the level of trust afforded by given model
252 ignificant attention, it is a technique that is limited by the low natural abundance of (29) Si and i
253 s cancer therapeutics, but their current use is limited by the low number of antigens restricted to c
254 high-brightness free-electron lasers (FELs) is limited by the microbunching instability, which can c
255 he developmental stage of the host brain and is limited by the migration time and the increasing size
258 However, the brightness of Antares in mice is limited by the poor solubility and bioavailability of
259 results suggest that recognition performance is limited by the poor spatial resolution at the back of
260 r these conditions, we show that wing growth is limited by the ranges of Dpp and Wg, and by ecdysone,
261 erize repetitive regions of the human genome is limited by the read lengths of short-read sequencing
262 This suggests that oil-to-methane conversion is limited by the recalcitrant nature of oil sands bitum
263 alization of these antiferromagnetic devices is limited by the requirement of material-specific const
264 astic syndrome (MDS), but long-term survival is limited by the risk of transplant-related complicatio
265 r, the ability to generalize current studies is limited by the small geographic scope as well as limi
267 e we show that vitamin C anticancer activity is limited by the up-regulation of the stress-inducible
268 been successful, but genome-scale screening is limited by the usual requirement of producing suffici
269 tric sensors functioning in equilibrium mode is limited by the value predicted according to the Nerns
272 rs associated with study-level heterogeneity was limited by the lack of availability of covariate dat
273 mmercial wines, the amplification efficiency was limited by the low amount of grapevine DNA and the p
276 herence than an automated EHR pull alone but was limited by the small number of patients identified.
280 ically and metabolically diverse microbiomes are limited by their destructive nature, low spatial res
282 couplings of nontriflate phenol derivatives are limited by their intolerance of halides including ar
284 the studies of diffusive metamaterials have been limited by their characteristic spatial inversion s
285 ity, yet their commercial implementation has been limited by their high cost to output power ratio.
286 ration into standardized in vitro assays has been limited by their incompatibility with packaging or
287 (+)) have been previously reported, but have been limited by their reliance on the electrocatalytic r
288 However, the cell permeability of PROTACs is limited by their high molecular weight and total pola
289 e imaging, computed tomography or ultrasound is limited by their insufficient spatial resolution.
290 f catalysts employing BrettPhos-like ligands is limited by their lack of stability at room temperatur
297 ), but accurate assessments of its potential are limited by uncertainty and variability in carbon acc
300 eous film-forming foam (AFFF)-impacted sites is limited by various processes that can retain PFAS mas