ライフサイエンスコーパス: be needed for

1 ging and automated analysis of cell dynamics are needed for a deeper understanding of tissue formatio

2 But how many records are needed for a representative measurement and when doe

3 tionships in CHANS, multiple approaches will be needed for a given causal question, with the aim of i

4 allel, using a compact gate design that will be needed for a large-scale semiconductor quantum proces

5 Significant preparation will be needed for a thorough, synchronized, and full withdra

6 SOTs that can arise in magnetic multilayers is needed for a formulation of a comprehensive SOT theor

7 r pathogens where guided affinity maturation is needed for a protective antibody response.

8 he coordinated efforts of >= 2 group members is needed for a successful rescue.

9 Therefore, a timely diagnosis is needed for a timely therapy and genetic counselling.

10 V7-dependent transcriptional complementation are needed for Abi/Enza resistance.

11 Simulation demonstrates that ESI are needed for accurate interpretation.

12 A reliable biomarker is needed for accurate and early differentiation between

13 better assess their potency and composition are needed for adequate studies of their safety and effi

14 enterocolitis, international collaborations are needed for adequately powered preventive trials.

15 the most socioeconomically deprived, support is needed for all affected families.

16 sease, the presence of LPS on mugwort pollen was needed for allergic sensitization.

17 New strategies are needed for ample representation of rare taxa and slo

18 rk of the 8 edition, where at least four PLN are needed for an N2 diagnosis, this threshold may be in

19 fixing bacterium Sinorhizobium meliloti 1021 is needed for an effective symbiosis with Medicago spp.,

20 A flexible and efficient R package is needed for analyzing processed multilevel or longitud

21 A novel method without such limitations is needed for antigenic variant identification.

22 Last but not least, accurate dating is needed for any further assessment of the societal and

23 Rapid and accurate diagnostic tools are needed for appropriate management of infectious diar

24 realization that a magnifying glass will be be needed for appropriate visualization.

25 n events, whereas those at the inner surface are needed for assembly of selective autophagy substrate

26 idence is mixed, and couple-based approaches are needed for assessing associations with reproductive

27 Even larger data sets will be needed for assessing reproducibility and for validati

28 ince the most recent common ancestor (MRCA), is needed for assessing the performance of reconstructio

29 iably identify a fleet-average hotspot, data are needed for at least 36-130 vehicles, depending on th

30 e yeast protein Atg8 (LC3 in mammals), which is needed for autophagosome formation.

31 Improved biomarkers are needed for axSpA to assist with early diagnosis and

32 ude carbon- and nitrogen-rich molecules that are needed for bacterial growth.

33 sion in macrophages, indicating this process is needed for bacterial replication niche formation.

34 covery of sigma(70) as a protein factor that was needed for bacterial RNA polymerase to accurately tr

35 Experimental models of the human brain are needed for basic understanding of its development an

36 We conclude that more research is needed for better screening and preventive strategies

37 ISG promoters following IFN stimulation and was needed for binding of STAT2 to these promoters.

38 Temporal baselines are needed for biodiversity, in order for the change in

39 Biosensors optimized for these wavelengths are needed for both next-generation microscopes and affo

40 Trpml is needed for both hemocyte migration and phagocytic pro

41 Higher-efficiency, lower-cost refrigeration is needed for both large- and small-scale cooling.

42 Hippocampus is needed for both spatial working and reference memorie

43 iminished surface tension, and a longer time was needed for both water and oil to wet and diffuse.

44 f ARABIDOPSIS THALIANA HOMEOBOX GENE1, which is needed for boundary establishment.

45 No sample preparation or internal standards were needed for calibration.

46 hem to a compact state, although Mg(2+) ions are needed for catalytic activities.

47 s its assembly to the exocyst complex, which are needed for cell protrusion formation and matrix meta

48 n the G(1) phase of the cell cycle, where it is needed for cell-cycle progression.

49 , it is not fully understood what components are needed for central MT-pair assembly as they are not

50 Effective regimens are needed for children with relapsed acute myeloid leuk

51 s show that both high OS levels and bacteria are needed for chronic wound initiation and development.

52 d therapy and is an area in which biomarkers are needed for clinical development.

53 rd task-relevant neurophysiological activity is needed for clinical and industrial applications as we

54 rk demonstrates that a specialized technique is needed for collecting small fibers to provide a more

55 Fewer pills were needed for complete adherence in women allocated no

56 ial comparing immediate with delayed surgery is needed for confirmation.

57 mmillary nucleus (SuM) to dentate gyrus (DG) is needed for contextual memory, social memory requires

58 In mice, SerpinB2 expression seems to be needed for coordination and timely resolution of infl

59 idely accepted that circulating immune cells are needed for coping with brain pathologies and that th

60 that high concentrations and thus high doses are needed for COVID-19 infections, but as yet there is

61 found that the transcription factor Pt-Ets4 is needed for cumulus integrity, dorsoventral patterning

62 and data analyses laborious, improved tools are needed for data analyses and extraction of key infor

63 While more research is needed for definitive conclusions and their applicati

64 cts and poor bioavailability, a new approach is needed for DHE delivery enabling painless self-admini

65 th ARPKD or other ciliopathies, abdominal US is needed for diagnosis and screening of portal hyperten

66 that sensitive noninvasive outcome measures are needed for diagnostic monitoring and early intervent

67 methods to linear models with mixed effects are needed for differential expression analysis.

68 high storage moduli and yield stresses that are needed for direct ink writing.

69 Finally, we show that PERK signaling is needed for directional axon migration and visual path

70 ata-driven "next-generation" approaches that are needed for discovery and understanding but that do n

71 genome, and estimates of recombination rates are needed for downstream analyses such as haplotype pha

72 rate specific projections of resilience that are needed for effective conservation planning.

73 Background: Evidence-based guidelines are needed for effective delivery of home oxygen therapy

74 While tumor antigens are needed for effective immunotherapy, a favorable tumo

75 hallenges the paradigm that extended opioids are needed for effective postoperative pain management.

76 sing these misconceptions and knowledge gaps is needed for effective management of deep-seabed mining

77 Automated techniques are needed for efficient and accurate identification of

78 rs greening their supply, greater resolution is needed for electric-sector emissions indices to evalu

79 rocatalysts that operate at low temperatures are needed for electrocatalytic hydrogenation (ECH) to u

80 d in renal tissue with a ureter, which would be needed for engineered kidneys to be clinically useful

81 ) exposure estimates at a fine spatial scale are needed for epidemiological studies.

82 tural tethers and a proper lipid composition are needed for ERTGoCS integrity.

83 g permissible chromatin environment can also be needed for estrogen-driven gene regulation to occur.

84 Other molecular imaging methods may be needed for evaluation of this malignancy.

85 high signal to noise and good photostability are needed, for example, in point-of-care testing.

86 , but the concurrent expression of both ORFs is needed for exclusion.

87 le technique, but high protein concentration is needed for experiments.

88 Rapid, low-cost methods are needed for extensive routine authentication of FMP p

89 Brief but more frequent handling was needed for familiarisation with cup handling, while

90 entify that >100 nM concentration of calcium is needed for folding of the BIg domains, and the stabil

91 t, suggesting that three-way sheet junctions are needed for formation of a diploid genome.

92 In addition, the PI4P effector Past1 is needed for formation of stable PI4KII-containing endo

93 placement of long sequences and genes, which are needed for functional genomics studies and trait imp

94 s a result, no image segmentation processing is needed for further analysis of nodule attenuation, al

95 radioligands for specific immune-mechanisms is needed for further clarification.

96 ative to the expansion of sample size, which is needed for further in-depth studies of the pathophysi

97 A substantial increase in food production is needed for future global food security.

98 erlying both PLP and NIBS-induced PLP relief is needed for future implementation of such treatment an

99 l stationary night blindness (CSNB) patients is needed for future therapeutic interventions.

100 Treatments are needed for gastroparesis; antagonists of tachykinin

101 occur after SE assembly and ERalpha binding are needed for gene responses.

102 gesting that an additional activity of MAML1 is needed for gene induction at a distance.

103 time-consuming because numerous repetitions are needed for gradient ramping and varying diffusion de

104 Accurate survival estimates are needed for guiding cancer control efforts in sub-Sah

105 BACKGROUND & AIMS: Effective treatments are needed for hepatic steatosis characterized by accumu

106 highlight that alternative treatment options are needed for hepatitis D.

107 deoxynucleoside triphosphates (dNTPs), which are needed for HIV-1 reverse transcription.

108 ontrolled and more effective waste treatment is needed for hospital wastewaters.

109 Improved treatments are needed for HSIL to reduce the burden of cervical can

110 No VG were needed for HV reconstruction.

111 ransplantation, but more screening campaigns are needed for identification of infected people in high

112 Scalable solutions are needed for identifying plant name mentions from text

113 eriments involving many conditions, a method is needed for identifying genes that exhibit significant

114 genous IL-33 treatment revealed that miR-155 is needed for IL-33-induced ILC2 expansion and eosinophi

115 Therefore, earlier detection of OA pathology is needed for improved disease management.

116 into account of the unloaded configuration, are needed for in vivo material parameter identification

117 or its D320A variant, we show that Asp(320) is needed for in vivo catalytic function, in vitro activ

118 At least five reliable fields were needed for inclusion.

119 Additional considerations are needed for indoor activities with large numbers of p

120 More-effective treatment strategies still are needed for infants with unfavorable biology stage 4

121 tivated microglia, consistent with K(+) loss being needed for inflammasome assembly.

122 to each other, suggesting that greater steps are needed for information about innovative practices to

123 Cit1810 is needed for interaction with the P-TEFb (positive tran

124 f ELNs induction, preclinical models of ELNs are needed for interrogation of these chemokines.

125 Identification of modifiable risk factors is needed for interventions aimed at reducing risk.

126 eckstrin homology domain and the SNARE motif are needed for its inhibitory function.

127 A controlled release of angiotensin-(1-9) is needed for its delivery to the heart.

128 contaminated sites, and thus, urgent action is needed for its removal from the environment.

129 Stormwater treatment systems may be needed for large-scale recharge in highly urbanized a

130 New drugs are needed for leishmaniasis because current treatments

131 Stored red blood cells (RBCs) are needed for life-saving blood transfusions, but they

132 nous synthesis of phosphatidylcholine, which is needed for lipoprotein synthesis, e.g., very low-dens

133 pulation modification with functional genes, is needed for long-term success.

134 Effective drugs are needed for lung cancer, as this disease remains the

135 interactions, alternative agents to rifampin are needed for management of staphylococcal periprosthet

136 More research and patient education are needed for managing expectations of postoperative pa

137 te ubiquitination determines which receptors are needed for maximal unfolding ability, and, in some c

138 gests that combining AKT and WEE1 inhibitors is needed for maximal efficacy.

139 te antiviral pathways active against EBV and was needed for maximal expression of several interferon-

140 Thus, new single-molecule methods are needed for measuring distances in the 8- to 25-nm ra

141 ions through time over large spatial extents is needed for meeting global biodiversity goals yet is i

142 or forensic applications, although more work is needed for method validation.

143 he number of persons who inject drugs (PWID) are needed for monitoring risk-specific infectious disea

144 ion of intraarterial delivery of bevacizumab is needed for more effective and personalized GBM treatm

145 immunotherapies and combinations likely will be needed for most subtypes.

146 munotherapy, continued ingestion of allergen is needed for most individuals to maintain desensitizati

147 , but it is unclear whether all interactions are needed for neutralization.

148 f upstream intermediaries (called IKKs) that are needed for NF-kappaB function.

149 lipids (30-45%), which mutant studies reveal are needed for normal C. jejuni motility at low oxygen c

150 ired for C. burnetii survival and growth but are needed for normal CCV development.

151 ient conditions, indicating that EXP1 indeed is needed for nutrient uptake and experimentally confirm

152 uggesting that consecutive rewarded episodes are needed for OFC computations that integrate reward hi

153 Although iron is needed for oligodendrocytes to produce myelin during

154 entification of robust prognostic biomarkers are needed for optimal disease management.

155 Evidence-based guidelines are needed for optimal prozone titrations.

156 while stable FAK oligomerization appears to be needed for optimal cancer cell proliferation in an an

157 hat the vesicular trafficking protein Rab39a is needed for optimal cross-presentation by dendritic ce

158 serine 31 (S31) of SKAP1 and the interaction is needed for optimal PLK1 kinase activity.

159 re, we show that serum response factor (Srf) is needed for optimal SC-mediated hypertrophic growth.

160 e peptide-1 receptor agonist semaglutide but are needed for oral semaglutide.

161 Additional treatment options are needed for patients who do not achieve sufficient re

162 hat are more practical and clinically useful are needed for patients with CKD.

163 er research and development of new therapies are needed for patients with PPI-refractory GERD symptom

164 Novel therapies are needed for patients with relapsed or refractory mult

165 Improved therapeutic options are needed for patients with relapsed or relapsed and re

166 New treatment strategies are needed for patients with severe asthma and explorato

167 stem cell transplantation, but alternatives are needed for patients without matched donors.

168 e on the submicrosecond to millisecond scale are needed for physical and chemical studies involving s

169 New tools are needed for physicians and healthcare providers to re

170 apse-to-nucleus communication processes that are needed for plasticity-associated gene expression.

171 e advocated for and that additional policies are needed for populations who shifted to nonfirearm sui

172 tial indicating the minimal somatic mutation is needed for potently neutralizing antibodies against S

173 od to switch the MIT properties in real time is needed for practical applications.

174 Biomarkers are needed for predicting the effectiveness of disease m

175 More immunogenic vaccines are needed for pregnant women living with HIV to enhance

176 st tube exposure, and that better strategies are needed for preventing this complication.

177 -to-perform human papillomavirus (HPV) tests are needed for primary cervical cancer screening in lowe

178 Effective strategies are needed for primary prevention and management of caro

179 Firm guidance is needed for primary care on the use of liver blood tes

180 Phenotype Ontology (HPO) terms] of a patient are needed for prioritizing the variants called from the

181 Financial support is needed for priority areas of research.

182 abdominal A and Notch, but additional inputs are needed for proper specificity.

183 ering and membrane reshaping activities that are needed for proper Z-ring assembly and function.

184 olarization or junction assembly, but rather is needed for proper junctional actin regulation during

185 ntly appreciated, and a fuller understanding is needed for proper understanding of cardiac calcium cy

186 that local depletion of actin-membrane links is needed for protrusion initiation.

187 that interdomain interactions within nSMase2 are needed for PS activation.

188 and effective vaccine, urgent consideration is needed for public health interventions in the Netherl

189 train PA14, suggesting no additional factors are needed for PumA function.

190 racterization of cardiomyocyte beat patterns is needed for quality control of cells intended for surg

191 0.07%, indicating that ultrasensitive assays are needed for quantification and analysis of ctDNA from

192 Diagnostics are needed for rapid identification of the cause of the

193 Strategies are needed for rapid repair of the epithelium to protect

194 e is high, and objective risk stratification is needed for rational use of advanced therapies such as

195 hate (eATP) by the purinergic receptor P2RX7 is needed for recirculating CD8(+) T cell memory, but it

196 in to address causation, an effective system is needed for refining this catalogue of differentially

197 ilment and the amount of energy storage that is needed for renewable integration.

198 achieve reproducible autonomy ratings and 40 are needed for reproducible overall operative performanc

199 ent of ocular lens density and transmittance is needed for research and clinical practice.

200 ized deceleration of the cleavage cycles and is needed for robust accumulation of zygotic gene produc

201 Copper ions are needed for several hallmarks of cancer.

202 Replication studies are needed for several other important outcomes (i.e., c

203 Bariatric outcomes are needed for shared decision-making and coverage polic

204 Only the A(22)W(30) motif was needed for SIVgsn71 Vpu to antagonize GSN BST-2, sug

205 Skin biomarkers are needed for skin barrier interventions studies.

206 glutamatergic synapse organizer Cbln1, which is needed for sociability in mice.

207 omologous group, but further diagnostics may be needed for some patients to determine adequate treatm

208 particular, light-activated regulatory RNAs are needed for spatiotemporal control of gene expression

209 Milligrams or more of material may be needed for speciated spectroscopic analysis.

210 Reciprocally, CIB1 was needed for stabilizing TMC6 and TMC8 levels.

211 Further studies are needed for standardizing its use.

212 Alternative strategies are needed for state-of-the-art deep learning models tha

213 ource of bacterial variety, starter cultures are needed for successful acidification of the cheese an

214 gration, means that self-generated gradients are needed for successful navigation.

215 , transport, and cargo delivery and function is needed for successful clinical implementation.

216 However, effective miRNA-delivery systems are needed for such approaches to be successful.

217 The large-area synthesis of Mo2 C film is needed for such applications.

218 technology-independent computational methods are needed for supervised cell type annotation of single

219 ole-plant water-use efficiency (WUE(plant) ) is needed for sustainable agriculture.

220 f this effect by 12 months means more effort is needed for sustained quitting.

221 A recent finding shows that IRF3 is needed for T cell effector functions that are involve

222 ceptors CXCR3 and CCR5, but neither receptor was needed for T cell recruitment to the salivary gland

223 p crystallization remain unclear, and models are needed for testing and expanding the understanding o

224 lts suggest that immune cells harboring EOPs are needed for the antihyperalgesic effects of sigma-1 a

225 d synapses; however, Ca(v)1.4 Ca(2+) signals are needed for the appropriate recruitment of postsynapt

226 imaging and pulmonary function tests (PFTs) are needed for the assessment of lung function during di

227 ions of the gut, but other bacterial factors are needed for the bacteria to adhere and colonize the i

228 They are needed for the correct formation of centrosomes, the

229 difficulties, and prostate-specific markers are needed for the detection of these cells using rare c

230 Therefore, novel chemical approaches are needed for the development of highly active and dura

231 Efficient contact investigation strategies are needed for the early diagnosis of tuberculosis (TB)

232 O) and secreted phospholipase A(2) (sPLA(2)) are needed for the formation of TLR4 agonists, which wer

233 e acute alcoholic hepatitis, further studies are needed for the identification of accepted selection

234 Therefore, robust analytical methods are needed for the in-depth characterization of rhEPO gl

235 er of loci of key transcription factors that are needed for the induction of adipogenesis, chondrogen

236 Alternative strategies are needed for the maintenance of euvolemia in heart fai

237 Much more work, focus and funding are needed for the novel approaches to result in effecti

238 New approaches are needed for the protection of biological cells from U

239 wever, it is not known whether these factors are needed for the regulatory T cell (Treg) arm of MHC c

240 nformation capturing data and analyzing them are needed for the study of 3D genome organization.

241 photolabile masked alkyne equivalents (MAEs) are needed for the synthesis of polyyne polyrotaxanes, a

242 More effective hypomethylating agents are needed for the treatment of myelodysplastic syndrome

243 f innovative technologies and processes that are needed for the water resource recovery facility of t

244 cells in the irradiated testes tissue would be needed for the effective TSE for spermatogenesis.

245 801 hold promise, but additional strains may be needed for the ongoing efforts of metabolic engineeri

246 Statistically principled analysis is needed for the accurate identification of gene hits a

247 only a small amount of ovary sample (<50 mg) is needed for the approach established in the current wo

248 ions between analyte and reagent ions, that is needed for the assessment of a chosen ionization sche

249 ultiorganisational stakeholder collaboration is needed for the development of functional, sustainable

250 n basic, translational and clinical research is needed for the development of new pain therapeutics a

251 of human iPSC and their cellular derivatives is needed for the development of safe and effective cell

252 A sensitive, quantitative and rapid assay is needed for the diagnosis of and, particularly, therap

253 Additionally, we found that Thpok is needed for the differentiation of thymic Treg precurs

254 E47 is needed for the efficient recruitment of GR and coregu

255 Less than 1 h is needed for the entire procedure that achieved a limit

256 of tinnitus research and treatment and what is needed for the field to achieve success.

257 For proteome-wide studies, additional time is needed for the integration of the proteomic and stati

258 The microtubule crosslinker NuMA is needed for the local load-bearing observed, whereas E

259 riasis remains uncharacterized, and a method is needed for the noninvasive monitoring of the developm

260 r, a better understanding of their mechanism is needed for the optimization or evolution of sequence

261 Localized cyclin B1-Cdk1 is needed for the proper release of MAD1 from the embrac

262 Such predictive understanding is needed for the rational design of intervention strate

263 The aminophenol compound that is needed for the second catalytic step can be prepared

264 ion, a brief period of junk-food deprivation is needed for the synaptic insertion of CP-AMPARs and th

265 monstrated that CENH3-Thr4 in the N-terminus was needed for the deposition as a positive phosphorylat

266 -alkylpyridines; acrolein or 2,4-alkadienals were needed for the formation of 3-alkylpyridines; and 2

267 al, secretion, and the C-terminal part of Ii were needed for the full adjuvant effect for Ab response

268 , due to the fact that higher cutting forces were needed for the higher hardness of SiC, sapphire and

269 e residence times, long-term feeding studies are needed for their evaluation.

270 s, MANF expression in adult mouse beta-cells is needed for their maintenance in vivo.

271 translating mRNPs, and recapping is all that is needed for their return to the translating pool.

272 s characterization of what is known and what is needed for theoretical chemistry comes up, as does th

273 cular mechanism of HIV-1 latency maintenance is needed for therapeutic strategies to combat existing

274 Inhibitors are needed for therapy, but development of potent, speci

275 Sensitive analytical methods are needed for these novel chemicals to assess the total

276 complications, but more rigorous evaluation is needed for these outcomes.

277 highly ordered arrangements of nanoparticles are needed for thin-film or membrane applications of GO,

278 es that no external in-plane magnetic fields are needed for this aim.

279 een reported to be poor, specific strategies are needed for this patient population.

280 our experiments, an alternative explanation is needed for this OCTP profile.

281 Additional doses of tocilizumab may be needed for those showing slow declines in CRP.

282 We show that maternally provided Plag1 is needed for timely mouse preimplantation embryo develo

283 embryogenesis, extensive cellular remodeling is needed for tissue morphogenesis.

284 teins; concerted movement of various domains is needed for transfer and ezetimibe blocks transport by

285 Such work is needed for translational as well as for basic science

286 ive outcome measures for disease progression are needed for treatment trials of Stargardt disease.

287 Diagnostic testing was needed for triage in up to 5% of case patients and 1

288 Targeted therapeutics are needed for triple-negative breast cancer (TNBC).

289 tflow, suggesting instead that about 30 eyes are needed for true mastery.

290 Novel drug regimens are needed for tuberculosis (TB) treatment.

291 tegral to the activity of the chaperonin and is needed for tumorigenesis.

292 Altered metabolism is needed for tumour cells to survive in this environmen

293 g and characterizing cryptic plant phenology is needed for understanding and accurate prediction at m

294 polycations disrupt and cross cell membranes is needed for understanding and controlling polycation-m

295 ations in psychosis, methodological advances are needed for us to investigate whether patients show a

296 man cytomegalovirus drugs from novel targets are needed for use instead of, or in combination with, c

297 UL21 also appears to be needed for viral membrane activities.

298 ar vaccinia virus-related kinases (VRKs) and is needed for viral DNA replication and likely other sta

299 n nor the clathrin heavy chain-binding motif were needed for virus infection, whereas the inositol ph

300 that shapes localized dendritic activity and is needed for vision to drive the emergence of binocular