ライフサイエンスコーパス: be poised for

1 by thalamocortical input in the neonate, but are poised for a remarkably coordinated development of f

2 The resulting vinylcyclobutane products are poised for a variety of further diversification reac

3 change the nucleotide sequence of that RNA, is poised for a major expansion in scientific interest a

4 this preoperative chemoradiotherapy strategy is poised for a randomized comparison with postoperative

5 Evolutionary biology is poised for a third major synthesis.

6 the duplex and that the metal binding domain is poised for abstraction of the T19 H4' in the minor gr

7 that has an unrestricted activation loop and is poised for access to membranes.

8 A motor is poised for action only when fully in contact with its

9 repressed to maintain pluripotency and that are poised for activation during ES cell differentiation

10 populations of human naive CD4+ T-cells that are poised for activation.

11 1 to be maintained in an inactive state that is poised for activation by calcium and membrane-localiz

12 These findings indicate that PRDM1 is poised for activation in lymphoma cells and therefore

13 tate of the CTNa(v), that is, the state that is poised for activation.

14 complex with Isc10 and Smk1 during MII that is poised for activation.

15 nce that naive neonatal human CD8(+) T cells are poised for an accelerated effector switch, with elev

16 stabilizes sharply bent bulge backbones that are poised for an in-line RNA cleavage reaction.

17 ain until, at its most advanced position, it is poised for another Heinrich event.

18 ction underlie DNA-sequencing platforms that are poised for application in personalized medicine.

19 s capture of a state in which the substrates are poised for attack on the dNTP.

20 ts helicase core in a manner that appears to be poised for binding to branched replication fork DNA s

21 methodological innovation ongoing, the field is poised for breakthroughs elucidating the developmenta

22 SNARE-complexin macromolecular assembly that is poised for Ca(2+) triggering of fusion.

23 ylate, and ISG15 thioester intermediate that are poised for catalysis of Uba7-UBE2L6-ISG15 thioester

24 "on" state, where the active site appears to be poised for catalysis (calcium acetate), or to what we

25 active site in the quaternary Pol mu complex is poised for catalysis and nucleotide incoporation proc

26 The D38N enzyme is poised for catalysis, but cannot execute because it l

27 conformation of the repressor, but one that is poised for cleavage after modest rearrangements that

28 Thus, Nob1 is poised for cleavage at the 3'-end of 18S rRNA.

29 ices have recently entered non-US trials and are poised for clinical studies in the US.

30 , biomarker-guided therapeutic strategy that is poised for clinical translation.

31 pulations of androgen-independent cells that are poised for clonal selection after androgen-deprivati

32 -plasma membrane prefusion intermediate that is poised for conversion to full fusion by Ca2+-dependen

33 and their importance will grow as the region is poised for decades of growth.

34 current therapeutic approaches, this system is poised for deeper exploration in research and clinica

35 0 complex in which a tetrameric transposase is poised for DNA cleavage.

36 Plant biology research, which is poised for dramatic advances, also depends fundamenta

37 Our results suggest grasslands are poised for drastic changes in function and highlight

38 ry is that some constrained nucleotides must be poised for efficient reaction at the 2'-hydroxyl grou

39 g C5 to C3 and generating a hydrated C4 that is poised for elimination as formate.

40 mparison with living systems, reconstitution is poised for ever more precise and informative understa

41 d of rapid development so that this organism is poised for exploitation as an industrial biotechnolog

42 res in the naive state, indicating that they are poised for expression prior to the initiation of plu

43 xpressed constitutively in that cell type or are poised for expression upon exposure to a stimulus.

44 sibility of a subset of genes on the Xi that are poised for expression.

45 open chromatin common among the GSCs tested were poised for expression of immune-related genes, incl

46 of the mycobacterial system reveals that it is poised for extremely efficient throughput: at saturat

47 rly iso-potential, revealing that complex II is poised for facile reverse electron transfer, which is

48 vidence of biocompatible nanoconstructs that are poised for further development toward the management

49 een reported to mark inactive enhancers that are poised for future activation.

50 ays, high transmission M.tuberculosis strain is poised for greater transmissibility.

51 the native state were found by simulation to be poised for helix formation in the denatured state.

52 open toward the periplasmic surface and ATP is poised for hydrolysis along the closed nucleotide-bin

53 x vivo T cells from T2D patients appeared to be poised for IL-17 production.

54 ant, functional Ag-specific CD8 T cells that are poised for immediate protection; however, this is at

55 Tissue resident memory CD8(+) T cells (Trm) are poised for immediate reactivation at sites of pathog

56 The 3' hydroxyl of the bound UMP is poised for in-line nucleophilic attack while contribu

57 e drug delivery systems in general appear to be poised for increased use in the clinic, whereas nanoe

58 diovascular prevention and population health are poised for innovation to guide evaluation and manage

59 group IIC intron-maturase retroelement that was poised for integration into a DNA stem-loop motif.

60 h the active-site sulfhydryl of cysteine-184 is poised for ionization by histidine-120, presumably en

61 lar loop 2 (EC2), however, suggests that EC2 is poised for key interactions.

62 of heptad target genes in CD34(+) cells that are poised for later expression, and we identify complex

63 The CTD is poised for local folding in an ordered structure that

64 asin settings, implying that these provinces are poised for mechanical failure and are therefore high

65 al IEGs, such as Arc (also known as Arg3.1), are poised for near-instantaneous transcription by the s

66 tic developmental disorder of the brain that is poised for neurobiological investigation.

67 icating that hUpf3 is in mRNP complexes that are poised for nuclear export.

68 O(2)F groups in the initially formed complex are poised for nucleophilic reaction with a targeted Tyr

69 the enzyme active site, where a bound water is poised for nucleophilic attack.

70 oxylate side chain of glutamate-166 as if it were poised for nucleophilic attack of the scissile este

71 al metaplasia, a dedifferentiated state that is poised for oncogenic transformation.

72 eries has improved membrane permeability and is poised for optimization.

73 The heme is poised for peroxidase activity with water bound in pl

74 s are ligated by D623 and D411 as the enzyme is poised for phosphoryl transfer.

75 n-deficient high-temperature superconductors are poised for power transmission and magnetic imaging a

76 to a primase x DNA x NTP x NTP complex that is poised for primer synthesis.

77 The field is poised for quantitative analysis of the various pathw

78 Uninduced heat shock genes are poised for rapid activation, with RNA polymerase II

79 These research areas are poised for rapid growth and will likely be central t

80 2 T-cell populations in healthy human beings are poised for rapid responses to bacterial or viral pat

81 wide, we show that the genome of naive cells is poised for rapid activation.

82 The uninduced Drosophila hsp70 gene is poised for rapid activation.

83 ynthetic signaling is relatively new, but it is poised for rapid advancement.

84 nitor with a preconfigured plastic phenotype is poised for rapid growth because it expresses, as need

85 o form a weakly populated excited state that is poised for rapid product release.

86 In this position, the carbonate is poised for re-entry into the active site and binding

87 d at the very onset of transcription when it is poised for reaction with a mononucleotide to form a t

88 rus, irrespective of reservoir distribution, are poised for reactivation during ART treatment.

89 associated with a conformation of MetH that is poised for reactivation of cobalamin by reductive met

90 ate that before induction, the Igkappa locus was poised for recombination; both alleles were in a con

91 ed RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-T

92 ent for mRNAs under translational arrest but are poised for release to actively translated pools.

93 an intermediate complex in which Dpp/Scw-Sog is poised for release by Tsg through specific disruption

94 vo, Foxp3-bound enhancer elements in the DNA were poised for repression only in activated Treg cells.

95 Our findings suggest salp are poised for reproductive success at birth, increasing

96 in vitro high-throughput screening platform is poised for screening large compound libraries for bet

97 The carotenoid market is poised for significant growth, with microbial product

98 The resulting ion-pair is poised for spontaneous electron transfer to O(2).

99 est genotyping panel currently available and are poised for successful deployment in other regions of

100 the hypothesis that the active site of CheY is poised for succinimide formation.

101 supercomplex in which two H3-H4 heterodimers are poised for tetramer assembly and discovered that CAF

102 onses to a broad range of microorganisms and are poised for Th1 responses before birth.

103 conformation, "primes" the enzyme so that it is poised for the docking of PKI and provides an explana

104 A under folding conditions (the R(N) state) is poised for the final folding step(s) with a native-li

105 to a transcriptionally active state; the PIC is poised for the formation of a transcription bubble an

106 The carboxy-terminal tyrosine kinase domains are poised for transactivation and to phosphorylate the

107 In non-t(8;21) myeloid precursors, PAX5 is poised for transcription, but is repressed by polycom

108 nd a dimethylated form of p53 (K382me2) that is poised for transcriptional activation of its target g

109 alphaHb, coordinate to the heme iron, which is poised for transfer into the heme-binding pocket of I

110 gy of AD + P is rapidly accelerating and may be poised for translational discovery.

111 g studies with DNA suggest that the two ions are poised for two-metal ion-dependent catalysis, but th

112 talytic domain, while A3G's catalytic domain is poised for ubiquitin transfer.

113 These results suggest that the GADD45 gene is poised for up-regulation and can be rapidly induced i

114 production of fewer, high-quality CPGs that are poised for updates as new evidence emerges.

115 Nonetheless, genomic technologies are poised for widespread translation to clinical practi