ライフサイエンスコーパス: be regulated to

1 ranscripts containing exons 1A1, 1A2, or 1A3 are regulated to a higher degree than transcripts contai

2 al (HM)/ferromagnet (FM) heterostructure can be regulated to a certain degree using an electric field

3 t initial step in O-glycan biosynthesis, may be regulated to a large extent by neighboring residue gl

4 of conditions, the mass of surviving systems is regulated to a few x 10(-5) to 10(-4) times the host

5 epends on its abundance and DRiP rate, which is regulated to a large extent by miRNAs.

6 As injury was regulated to a larger extent by the glutathione cont

7 11% of the genes cold regulated in wild type were regulated to a similar extent in all genotypes (chl

8 The internal environment of the ER is regulated to accommodate essential cellular processes

9 Much of animal behavior is regulated to accomplish goals necessary for survival

10 ever, it remains to be determined how dynein is regulated to accomplish its varied roles.

11 functions of Cdc14 and how this phosphatase is regulated to accomplish the coupling of mitotic proce

12 with a focus on how CD8(+) T cell responses are regulated to achieve different immune outcomes.

13 ain how the distributions of BMP and Chordin are regulated to achieve patterning, but the assumptions

14 reas, and the polymer-water interactions can be regulated to achieve desirable water retention, absor

15 focus on understanding how the m(6)A pathway is regulated to achieve control of m(6)A-containing mRNA

16 ndamental difference in how dopamine release is regulated to achieve distinct functions: broadcast bu

17 uestion is whether and how DNA translocation is regulated to achieve sliding versus ejection.

18 cell cycle, little is known how this enzyme is regulated to achieve targeted effects on specific his

19 Much work has focused on how transcription is regulated to achieve these changes; however, in many

20 r is much known about how the immune network is regulated to achieve this antitumor response.

21 scuss recent insights into how inflammasomes are regulated to activate caspase-1 and implicated in hu

22 cate multiple levels at which insulators can be regulated to affect gene expression.

23 for degradation and whether this process can be regulated to affect intercellular communication is un

24 d how the cell wall deposition and structure are regulated to allow for rapid changes in the directio

25 these studies provide insight into how heme is regulated to allow effective erythropoiesis, show tha

26 at the mass fraction of its satellite system is regulated to approximately 10(-4) by a balance of two

27 ected cell, raising the question of how they are regulated to avoid cell killing outside the context

28 weat glands, salt excretion and reabsorption are regulated to avoid electrolyte imbalance.

29 Toll-like receptor (TLR) responses are regulated to avoid toxicity and achieve coordinated

30 dity at such plasma-based ion sources should be regulated to avoid approximately 90% shifts in relati

31 Copper ion uptake must be regulated to avoid both deficiency and excess because

32 mammalian telomeres, but its synthesis must be regulated to avoid excessive resection of the 5' end,

33 Oxidative protein folding needs to be regulated to avoid hyperoxidation.

34 ion is how such destabilizing activity might be regulated to avoid membrane and cellular damage, and

35 ed function in the virus life cycle and must be regulated to avoid nonspecific RNA degradation.

36 Platelet production must be regulated to avoid spontaneous bleeding or arterial o

37 but little is known about how this activity is regulated to avoid excessive tethering of the genome.

38 These cell compartments are regulated to balance proliferation and stem cell ren

39 How these outputs are regulated to balance the cellular requirement for en

40 as phosphoenolpyruvate carboxylase (PEPC1), are regulated to be expressed at high levels and in a ce

41 nstrate for the first time that septal pores are regulated to be opened during interphase but closed

42 How the blood-gas barrier is regulated to be extremely thin but sufficiently stron

43 lular trafficking of the SUMOylation enzymes is regulated to catalyze SUMOylation in different cellul

44 How ATG4 activity is regulated to co-ordinate these events is currently un

45 adherin-actin network formation and how they are regulated to coincide with initiation of adhesion.

46 However, how the PPP is regulated to confer a selective growth advantage on c

47 How LINC complexes are regulated to connect nuclei to the cytoskeleton duri

48 Inside cells, the vast majority of kinesin-1 is regulated to conserve ATP and to ensure its proper in

49 How niche capacity is regulated to contain a specific number of NSCs remain

50 How the MPCs are regulated to continuously release cells into the pre

51 further means by which costimulatory signals are regulated to control self-reactivity.

52 the mechanism by which these or other motors are regulated to control the direction of organelle tran

53 as how the physiology of nematode sperm may be regulated to control motility as it is in mammals.

54 However, how HDAC6 itself is regulated to control cell motility remains elusive.

55 aperone glucose-regulated protein 94 (GRP94) is regulated to control cell surface receptor signalling

56 f centriole biogenesis, but how its activity is regulated to control centriole assembly is unclear.

57 Transposition in many organisms is regulated to control the frequency of DNA damage caus

58 the way to elucidate how polar Tfp machines are regulated to coordinate multicellular movements, a c

59 (folding), stabilization, and unfolding must be regulated to coordinate G4-mediated biological functi

60 f actin assembly, yet how the WAVE signaling is regulated to coordinate actin assembly with mitotic e

61 for the first time how mycothiol metabolism is regulated to cope with stress from thiol reactive tox

62 Signaling protein movement is regulated to create gradients, control amounts, impos

63 S) in Aspergillus nidulans, we find that MTs are regulated to depolymerize within forming fungal biof

64 me synthesis dynamics and termination events are regulated to determine the length of these critical

65 derstand how neurogenesis in the adult brain is regulated to develop strategies that harness neural s

66 lial cell (EC) identity and EndoMT mediators is regulated to drive this transition.

67 the various steps of COPII-mediated ER exit are regulated to efficiently transport diverse cargoes.

68 known about how syndecan ectodomain shedding is regulated.To elucidate the mechanisms that regulate s

69 le myosin IIA (NMMIIA) at collagen adhesions are regulated to enable collagen phagocytosis.

70 activated state, but it is unclear how this is regulated to enable the channels to adapt to differen

71 ocyte function-associated antigen-1 [LFA-1]) is regulated to engage and maintain T cell adhesion.

72 It remains unclear how their kinetochores are regulated to ensure faithful chromosome segregation.

73 into how meiosis-specific cohesin complexes are regulated to ensure formation of euploid gametes.

74 These are regulated to ensure homeostasis both systemically in

75 During mitosis, microtubule dynamics are regulated to ensure proper alignment and segregation

76 vely little is known about how these enzymes are regulated to ensure sphingolipid homeostasis.

77 The acquisition and modulation of motility are regulated to ensure that sperm move when and where n

78 Mitotic kinesins must be regulated to ensure a precise balance of spindle forc

79 This proliferation must be regulated to ensure an effective response to infectio

80 ied as a biological agent and its use should be regulated to ensure patient safety.

81 GINS (CMG) replicative helicase complex must be regulated to ensure that DNA unwinding is coupled wit

82 Therefore, expression of R-M genes must be regulated to ensure that enough methyltransferase is

83 ession of amino acid degradative enzymes may be regulated to ensure that high levels of these enzymes

84 y of virus capsids and surface proteins must be regulated to ensure that the resulting complex is an

85 and thus the timing of their expression must be regulated to ensure that they act at the appropriate

86 Eukaryotic DNA replication is regulated to ensure all chromosomes replicate once an

87 requires crossover (CO) recombination, which is regulated to ensure at least one CO per homolog pair.

88 nctions and how lipopolysaccharide transport is regulated to ensure balanced growth of all envelope l

89 the spatial organization of heterochromatin is regulated to ensure epigenetic silencing remains uncl

90 Mineral content of complete pet food is regulated to ensure health of the companion animal po

91 However, just how MCC is regulated to ensure normal mitosis during cellular di

92 How Zpr1-mediated folding is regulated to ensure rapid Zpr1 recycling remains an u

93 ange factor responsible for RhoA activation, is regulated to ensure spatiotemporal control of contrac

94 egabase mouse Igh locus, V(D)J recombination is regulated to ensure specific and diverse antibody rep

95 V(D)J recombination substrate choice is regulated to ensure that the appropriate gene segment

96 Proteasome assembly is regulated to ensure the enzyme is inactive until its

97 is one mechanism by which SMARCAL1 activity is regulated to ensure the proper level of fork remodeli

98 amental question has been whether germ cells are regulated to enter the meiotic cell cycle (i.e., mit

99 allenge is to unravel how genes interact and are regulated to exert specific biological functions.

100 How chromatin dynamics are regulated to facilitate this process in chromatin is

101 nd this decline in somatic maintenance might be regulated to facilitate resource reallocation towards

102 on, and demonstrate that this expression can be regulated to facilitate studies of human alpha7-nAChR

103 The process is regulated to facilitate efficient nutrient use and me

104 known about how this core enzymatic activity is regulated to facilitate sister chromatid cohesion.

105 The neonatal immune system is regulated to favor anti-inflammatory and tolerogenic

106 How sphingolipid synthesis is regulated to fulfill these physiological requirements

107 ndance and dynamic range, and concentrations are regulated to functional demands.

108 Here, we address how bric a brac is regulated to generate the mature expression patterns

109 thermore, the expression of the Ath5 protein is regulated to give a non-random dispersed pattern of R

110 of the decapping enzyme and how its activity is regulated to give rise to differential mRNA turnover.

111 It is important to understand how autophagy is regulated to identify ideal therapeutic targets for t

112 infection, but how its strength and duration are regulated to impact combination therapy efficacy rem

113 bolism, and aminoacyl-tRNA biosynthesis that were regulated to improve the defense of tolerant variet

114 panding our understanding of how methylation is regulated to include inputs from both genetic and epi

115 tests have yet determined if statolith mass is regulated to increase or decrease gravity stimulus to

116 it is unclear which Myc target genes need to be regulated to induce growth and whether multiple targe

117 Here we discuss how gasdermin pore formation is regulated to induce membrane permeabilization or lysi

118 en on understanding how protein-coding genes are regulated to influence protein expression.

119 Even if each property can be regulated to its target value when considered in isol

120 significant tissue injury, phagocytosis must be regulated to limit damage to the host while allowing

121 rrently unknown how Galphai-Pins-Mud binding is regulated to link cortical polarity with spindle orie

122 Our understanding of how stem cells are regulated to maintain appropriate tissue size and ar

123 ular methods by which inflammatory responses are regulated to maintain intestinal homeostasis and the

124 rotein Insig, HMGR synthesis and degradation are regulated to maintain sterol homeostasis.

125 How the structural components of the SC are regulated to maintain the architectural integrity of

126 occus pneumoniae produces three aPBPs, which are regulated to maintain the bacterium's ovoid shape.

127 iNKT cell responsiveness must be regulated to maintain effective host defense while pr

128 Under these conditions, the cell volume must be regulated to maintain optimal neural function.

129 trations above S*, transporter abundance can be regulated to maintain uptake rates as demanded by max

130 e mechanisms by which neuropeptide signaling is regulated to maintain E/I balance remain uncertain.

131 tiple mechanisms by which the level of IgG1) is regulated to maintain immune system and host homeosta

132 However, how BRD4 is regulated to maintain its normal function in healthy

133 nal copper exporter and that its trafficking is regulated to maintain systemic copper homeostasis.

134 estion of whether activity of these proteins is regulated to maintain zinc homeostasis.

135 naptic as well as intrinsic conductances can be regulated to make a self-assembling central pattern g

136 How these enzymes are regulated to mark specific genomic regions as hetero

137 ood flow to dynamically contracting myocytes is regulated to match O(2) delivery to metabolic demand.

138 tivity of downstream intracellular effectors is regulated to mediate gene expression changes have not

139 is unknown how its transport characteristics are regulated to meet acutely changing demands.

140 ch conformational rearrangements in proteins are regulated to meet the needs of cells under changing

141 are controlled by Ca(2+) handling, which can be regulated to meet demand.

142 oteasomes are coupled to motors and how this is regulated to meet changing demand for protein breakdo

143 Golgi turnover is regulated to meet different cellular physiological de

144 , it remains unclear how apicobasal polarity is regulated to meet the opposing needs for tissue plast

145 ng how steps during any such maneuver should be regulated to minimize error costs, consistent with th

146 s necessary for carbon assimilation and must be regulated to minimize free radical damage.

147 nough for effective bypass, but it must also be regulated to minimize replication errors by the TLS P

148 that the interaction with biological systems is regulated to minimize toxicity for biological functio

149 n to ask questions about how these cells can be regulated to mitigate the collateral destruction asso

150 ergo S-palmitoylation, how this modification is regulated to modulate specific biological functions i

151 Synaptonemal complex (SC) formation must be regulated to occur only between aligned pairs of homo

152 Crossing over is regulated to occur at least once per each pair of hom

153 ogenitor cell response in diseased liver may be regulated to optimize liver regeneration and minimize

154 The fermentation times were regulated to optimum bread height for each treatmen

155 e mechanisms by which insulator activity can be regulated to orchestrate changes in the function and

156 bules and the actin cytoskeleton, and how it is regulated to orient the spindle according to cellular

157 How dynein is regulated to perform these activities with spatial an

158 viruses and plasmids, but how these systems are regulated to prevent autoimmunity is poorly understo

159 nown how these potentially autolytic enzymes are regulated to prevent lethal breaches in the cell wal

160 ing the bacterium of its intracellular niche are regulated to prevent overexuberant inflammation.

161 Immune responses need to be regulated to prevent autoimmunity.

162 protection against infections but must also be regulated to prevent autoimmunity.

163 that detect intracellular nucleic acids must be regulated to prevent inappropriate activation by endo

164 RNA editing must be regulated to prevent premature and excessive accumula

165 tabolic process in which catalase expression is regulated to prevent damage while preserving an H(2)O

166 y of the mitochondrial transcription factors is regulated to prevent DNA binding at inappropriate tim

167 have been identified, how NLRP3 inflammasome is regulated to prevent excessive inflammation is unclea

168 e balance between death and survival signals is regulated to prevent immunodeficiency and autoimmunit

169 vators, it is unclear how the contact system is regulated to prevent uncontrolled clotting.

170 How genes are regulated to produce the correct assortment of prote

171 on from dynamic liquids to stable fibers may be regulated to produce cellular structures with diverse

172 e dynamic behavior of the actin cytoskeleton is regulated to produce extension or retraction.

173 In muscle, the assembly of sarcomeric myosin is regulated to produce stable, uniform thick filaments.

174 g that during cell development, CSC movement is regulated to produce wall structures optimized for ce

175 Ag receptor loci are regulated to promote allelic exclusion, but the mech

176 es that Src kinase activity does not need to be regulated to promote cell migration and FAK phosphory

177 that the biophysical properties of cells can be regulated to promote survival under conditions of nut

178 length in C. elegans and suggest that length is regulated to promote efficient transcriptome surveill

179 ns to be learned including how PA-X activity is regulated to promote optimal levels of viral infectio

180 The immune system is regulated to protect the host from exaggerated stimul

181 Biological processes are regulated to provide cells with exquisite adaptabili

182 r insight to how actin integration at the AJ is regulated to provide stability under mechanical load.

183 and secretion are well established, how they are regulated to rapidly fine-tune secretion in response

184 This finding demonstrates that NCOAT may be regulated to reduce the state of glycosylation of tra

185 upply of Sre1, Sre1 precursor synthesis must be regulated to replenish Sre1 precursor lost to proteol

186 ability of the M. tuberculosis envelope that is regulated to resist stresses encountered in the host.

187 mediates through lipid biosynthetic pathways is regulated to respond to nutritional and environmental

188 How each NPF functions and is regulated to restrict actin assembly to late stages o

189 In oxygenic photosynthesis, light harvesting is regulated to safely dissipate excess energy and preve

190 tine and, in particular, on how the CCK cell is regulated to secrete its hormone product.

191 tion of plastic clean-up technologies should be regulated to secure their net benefits and avoid unin

192 The amplitudes of these barriers can be regulated to simulate channel gating.

193 e is retained, as though protrusive activity is regulated to some set point.

194 hat cellular and synaptic properties need to be regulated to specific values to allow a neuronal netw

195 However, we do not know how TRAIP's activity is regulated to stop uncontrolled replisome unloading.

196 However, how PARP-1 signaling is regulated to switch its function from DNA repair to c

197 an endothelial-like cell population that can be regulated to treat cardiac hypertrophy by improving n

198 y demonstrates how different synaptic inputs are regulated to tune a neuron to respond to specific fe

199 encode all ribosomal proteins in mammals and are regulated to tune ribosome synthesis to cell state.

200 rein Rad53 activity and Rad9 oligomerization are regulated to tune the DNA-damage response.

201 omplete understanding of how these receptors are regulated to tune their signaling to specific neurop

202 is known about how genes and neural circuits are regulated to turn on/off behaviors.

203 fferent receptors and how the spike proteins are regulated to undergo conformational transitions.