ライフサイエンスコーパス: be relieved by

1 s apparent inhibition of channel conductance was relieved by 1 microM diazepam.

2 cintigraphy with (201)Tl/(123)I-BMIPP, which was relieved by 1-year treatment of glucocorticoid combi

3 with dinitrogenase causes inhibition, which is relieved by 2OG.

4 bes and associated metabolites, but symptoms are relieved by a Bacteroides fragilis probiotic.

5 ion of class III/IV flagellar genes that can be relieved by a gain-of-function mutation in flbD calle

6 inhibition by its C-terminal tail, which can be relieved by a phosphoinositide to stimulate flippase

7 the gxySBA operon, the function of which can be relieved by a subset of the transported sugars, inclu

8 the inhibition placed upon the output domain is relieved by a conformational change that alters inter

9 mediated transcriptional repression in vitro is relieved by a match polyamide but not by a mismatch p

10 onal strain in an IHF-mediated DNA kink that is relieved by a nick (at least 0.76 kcal/mol) and pinpo

11 in the SOD-competent parental strain, and it was relieved by a cell-permeant mimic of SOD activity; h

12 hieved by showing that the growth inhibition was relieved by a mutation in a single residue in the ca

13 ifferentiated until Pax3-mediated repression is relieved by activated beta-catenin.

14 xpression of G alpha(o), and this inhibition is relieved by activation of alpha2A-adrenergic receptor

15 9-induced platelet aggregation by Ro 31-8220 was relieved by activation of the G(i) pathway by select

16 This inhibition is relieved by added H2, resulting in a lowering of the

17 This metabolic block could be relieved by addition of the alpha-ketoglutarate precu

18 )-1- or Cu-stimulated VEGF expression, which is relieved by addition of excess Cu.

19 from the prgQ promoter, and this repression was relieved by addition of exogenous cCF10.

20 iate receptor stimulation in the VTA and can be relieved by administration of the dopamine receptor a

21 7-OH substituent and the substrate C2 carbon is relieved by adopting the globally strained structure.

22 and subchondral bone thickening, which could be relieved by alleviating ER stress via PBA administrat

23 RNA-mediated inhibition of holo-PRC2 is relieved by allosteric activation of PRC2 by H3K27me3

24 )A and CaMb domains with the MUN domain that are relieved by alphaRIMs and calmodulin.

25 This depression was relieved by amacrine cell inhibitory feedback that a

26 l rickettsial infection, and the suppression was relieved by aminoguanidine.

27 This inhibition is relieved by AMP, an allosteric activator of this regu

28 tive effect displayed by the HA2 protein can be relieved by an additional mutation in HA2 RNase T tha

29 Profilin-mediated INF2 inhibition is relieved by an anti-N-terminal antibody for INF2 that

30 The experience of depression being relieved by another pregnancy may be a previously

31 ation in a patient with continuous pain that is relieved by anti-inflammatory drugs may point to an o

32 and that many of the features of the illness are relieved by antibiotic therapy.

33 datively stressed and oxidative stress could be relieved by antioxidant treatment, leading to improve

34 agitation and stereotypical behaviors, which are relieved by antipsychotics.

35 for its activity, but this dependence could be relieved by any of six amino acid substitutions in th

36 ical obstruction to left ventricular outflow is relieved by aortic valve replacement.

37 hese two steps in the cross-linked actin can be relieved by appropriate factors.

38 gically important effect), this obstacle can be relieved by at least two strategies for exposing regu

39 inhibitory effect of secretin and ACh could be relieved by atropine, and by the protein kinase C (PK

40 ADP inhibition of bacterial Hsp90 can be relieved by bacterial Hsp70 and an activating client

41 Second, the resultant membrane strain is relieved by bending and by creation of exovesiculated

42 This novel mode of autoinhibition is relieved by binding of another ligand to WW3.

43 he Vps4p MIT domain and that this inhibition is relieved by binding of either Type 1 or Type 2 MIM el

44 basal catalytic activity of PLCdelta1, which is relieved by binding of Gbetagamma subunits to PLCbeta

45 enzymes exhibit an autoinhibitory state that is relieved by binding to nucleosomes, enabling dimethyl

46 were CD8(+)CTLA-4(+), and their suppression was relieved by blockade of CTLA-4, but not IL-10 or TGF

47 Thus, the barriers posed by 53BP1 and RAP80 are relieved by BRCA1 and POH1, respectively.

48 drates and severe defects in cleavage, which were relieved by brefeldin A treatment; (iii) bNAbs that

49 l factors to achieve growth regulation could be relieved by bringing the E2F1 activation domain to th

50 s symptoms through hyperinflation, which can be relieved by bronchoscopic lung volume reduction (BLVR

51 y (PH) domain and its kinase domain that can be relieved by C-tail phosphorylation.

52 n EPS biosynthesis, and that this repression is relieved by c-di-GMP.

53 omology (PH) domain and kinase domain, which is relieved by C-tail phosphorylation, but the precise m

54 xin does not function as a fusion clamp that is relieved by Ca(2+)-synaptotagmin.

55 Furthermore, C2B inhibition is relieved by calcium binding to C2B, while the neighbo

56 MEF2 activity only when repression by HDACs is relieved by CaMK signaling to the DNA-binding domain.

57 ree-generation Canadian family in which pain is relieved by carbamazepine (CBZ).

58 H-rev107 transcription in these cells could be relieved by chemically induced hypomethylation with 5

59 s packing stress on the lipid bilayer, which is relieved by CL remodeling to form tightly packed lipi

60 We demonstrate that strain in pBn can be relieved by cleaving the linker with a chemical reage

61 intestinal epithelial denudation that cannot be relieved by co-deletion of Trp53.

62 However, S6K1 sensitivity to osmotic stress was relieved by co-overexpression of RAPTOR1.

63 to cell proliferation; this inhibition could be relieved by coexpression of a cyclin B1 derivative th

64 This constraint is relieved by coexpression of SSP in trans, allowing tr

65 The block was relieved by coexpression of a U12 snRNA containing c

66 T expression in Xenopus oocytes was found to be relieved by coinjection of transcripts from other def

67 al rearrangement, whereby autoinhibition can be relieved by competitive sequestration of the autoinhi

68 MA-mediated inhibition is relieved by concentration-dependent Gag multimerizati

69 its own binding, and in that case repression is relieved by cooperative interactions with SNAP(c).

70 on fkh-6 expression and gonadogenesis, which is relieved by cyclin D activity.

71 ak at night when dopamine levels are lowest, are relieved by D3 agonists, and likely involve increase

72 habdomyolysis triggered by infections, which were relieved by dantrolene in 1 patient.

73 These hypermorphic phenotypes could be relieved by deleting more of the N terminus, or in so

74 This suppression was relieved by deletion and mutation of the miR-206-bin

75 share an unusual property whereby inhibition is relieved by depolarization, demonstrating a state-dep

76 his system seems to be oxidative stress that is relieved by dipyridamole.

77 actions on the phosphate moiety of bound R1P are relieved by dissociation of R1P from PNP or by hydro

78 the stalling of PolB1 at the lesion site can be relieved by Dpo4.

79 nd the RASSF1A-induced cell cycle arrest can be relieved by ectopic expression of cyclin D1 or of oth

80 to participate in gene suppression that can be relieved by EGFR signal, but we found that cic also a

81 Both blocks in HIV-1 replication can be relieved by either expression of the appropriate huma

82 Autoinhibition of Ets-1 could be relieved by either protein partner(s) or posttranslat

83 icylic acid-dependent resistance pathway and is relieved by either a mutation in EDS1 or the presence

84 on both dividing and nondividing HeLa cells was relieved by either pharmacological or genetic disrup

85 These disruptive effects were relieved by either mutation of the catalytic residu

86 ss, and that the inhibitory activity of NIFL is relieved by elevated levels of 2-oxoglutarate when PI

87 nhibition of beta-actin folding by PDCL3 can be relieved by exchanging its acidic C-terminal extensio

88 ctivity of the promoter, and this repression is relieved by exogenous sphingosine.

89 ced by COX-2 inhibitors, and this inhibition was relieved by exogenous supplementation with PGE(2).

90 onsequences of the inhibition of PI 3-kinase are relieved by expression of a constitutively active fo

91 These effects could be relieved by expression in trans of the ltrA gene clon

92 ATG-mediated inhibition of transformation is relieved by expression of constitutively active Rac1,

93 The block is voltage dependent, is relieved by extracellular potassium and has rapid kin

94 mpairment to PBD-substrate interactions that is relieved by EYA-mediated dephosphorylation.

95 (N = 565), we test whether this tension can be relieved by framing choices as inclusive (allowing se

96 e that the inhibitory activity of PTC124-AMP is relieved by free coenzyme A, a component present at h

97 This requirement of Sec14p is relieved by genetic inactivation of the cytidine diph

98 in the flipped-out nucleotide substrate that are relieved by glycosylic bond cleavage in the product

99 type; however, the acid-sensitive phenotype was relieved by growth in the presence of long-chain mon

100 how Ptc inhibits Smo and how such inhibition is relieved by Hh stimulation.

101 ation of core histones at promoter sites and is relieved by histone deacetylase inhibitors.

102 tube formation, and this suppressive effect was relieved by HIV Tat.

103 ted by the feoB mutant in Fe-deficient media was relieved by human holo-transferrin, holo-lactoferrin

104 In eukaryotic cells, this inhibition is relieved by hydrolysis of SAH to adenosine and homocy

105 Upon mitogen stimulation, this repression is relieved by hyperphosphorylation of Rb by the cyclin

106 This requirement can be relieved by inactivation of the cytosine 5'-diphospha

107 We show that this repression is relieved by inactivation of FOXO1 by insulin, which l

108 ration (median age 55.4 months), obstruction was relieved by incision of hypertrophied anomalous musc

109 of lateral root initiation in WT plants can be relieved by increased concentrations of external nitr

110 established but not understood, was found to be relieved by increased expression of a DUB that promot

111 orted by data showing that growth inhibition is relieved by increasing concentrations of tryptophan i

112 ts that strain, introduced by the disulfide, is relieved by increasing the twist of the long-pitch ac

113 diated mecA transcriptional repression could be relieved by induction through homologous but not hete

114 ng conferred by MeCP2 and methylated DNA can be relieved by inhibition of histone deacetylase, facili

115 ucture and a transcriptional repression that is relieved by inhibition of DNA methylation.

116 cordingly, repression in the absence of MLL2 is relieved by inhibition of PRC2 and DNA methyltransfer

117 sed by ethambutol or isoniazid treatment may be relieved by iniBAC to increase the chance of bacteria

118 Once glucotoxicity is relieved by insulin therapy, beta-cell function parti

119 nce spectroscopy that the autoinhibition can be relieved by integrin or integrin regulator migfilin.

120 eavage of domain A2, and that inhibition can be relieved by interaction of domain A1 with platelet GP

121 This inhibition can be relieved by interaction with protein partners or coop

122 esses its own binding to DNA, and repression is relieved by interactions with the Oct-1 POU domain th

123 rly block to HIV-1 infection in monkey cells is relieved by interference with TRIM5alpha expression.

124 of one insertion variant reveals that strain is relieved by intermolecular folding with an identicall

125 5 of 5 (100%) consecutive patients, and this was relieved by intracoronary nitroglycerin in 5.5+/-3.5

126 The transdominant phenotype can be relieved by introducing a second mutation in the DNA-

127 volves cooperation between DNMT1 and p53 and is relieved by introduction of DNMT1- or p53-specific sm

128 transcription from the irr promoter in vitro was relieved by Irr.

129 Here, we show that the polar barrier is relieved by ISW2, an ATP-dependent chromatin remodele

130 mediate gene repression, and this repression is relieved by JNK-mediated c-Jun N-terminal phosphoryla

131 The repression was relieved by laminaribiose, also in a dose-dependent

132 LPO neurons produces an aversive state that is relieved by LHb MOR activation, and optogenetic inhib

133 diated autoinhibition of the HECT domain can be relieved by linker post-translational modifications,

134 the repression of the fadBA5 operon by PsrA is relieved by long-chain fatty acids (LCFAs).

135 /C interaction on activation function 2 that was relieved by MAGE-11.

136 Repression by GAL4-MBD3L2 is relieved by MBD2 and vice versa, and repression by MB

137 epression by MBD2 from a methylated promoter is relieved by MBD3L2.

138 ver, the suppression of rdgA-tacZ expression is relieved by MC in the RecA+ E. coli strain MC4100, bu

139 studies demonstrated that LTGO-33 inhibition was relieved by membrane depolarization, suggesting the

140 ions 1 and 2, noted above, could conceivably be relieved by migration of the acyl group to the neighb

141 It is proposed that this steric strain can be relieved by migratory insertion, to give a five-coord

142 ATA6 represses MIR100HG, but this repression is relieved by miR-125b targeting of GATA6.

143 This actin inhibition is relieved by Mn(2+), providing a direct and experiment

144 rough these potential escape mutations could be relieved by modifications to vaccines.

145 ation; upon TNF stimulation, the suppression is relieved by Mule/ARF-BP1-mediated Miz1 ubiquitination

146 ethoprim (TMP) prevents growth, but this can be relieved by murine DHFR (mDHFR).

147 tially in G0/G1 thymocytes; this restriction is relieved by mutation of Thr-490 to alanine (T490A).

148 When repression of the H1t promoter was relieved by mutation of GC box 2, additional mutatio

149 Cell death induction was relieved by mutation of the BAR domain, a putative e

150 ere, we show that this catabolite repression is relieved by mutations that weaken the DNA site for Fi

151 on of the hTERT promoter and this repression was relieved by Myc overexpression.

152 The inhibition of NAMPT by AMP can be relieved by NAMPT activators or adenosine triphosphat

153 when competition for H(2) inside the biofilm was relieved by nearly complete removal of NO(3)(-).

154 asm, and that the importin-alpha aggregation is relieved by NLS peptide binding, with the importin-al

155 The inhibitory activity of p85 is relieved by occupancy of the NH(2)-terminal SH2 domai

156 We show that this TFII-I inhibition is relieved by one of the previously defined viral activ

157 gy of approximately 8 kcal mol-1 which could be relieved by opening the s-cis lactone ester bond to a

158 teins avoids adventitious expression and can be relieved by other DNA-binding counter-silencing prote

159 nt on the p300-binding domain of E1A and can be relieved by overexpression of p300.

160 rature-sensitive growth, but this defect can be relieved by overexpression of YPT6.

161 to growth rate reduction, and this reduction was relieved by overexpression of tRNA(1)(Pro).

162 pneumophila in broth, and growth inhibition was relieved by overproduction of LppA or by metal ion t

163 p53-mediated repression of RelA is relieved by p300 overexpression and the increased Rel

164 main on binding of the Fyn SH3 domain to CD2 was relieved by peptides containing a phosphorylated YEE

165 pressed by the histone modifier HDAC2, which is relieved by pharmacological inhibition of histone dea

166 Ser-473 phosphorylation and entry into G2/M was relieved by PHLPP phosphatase inhibition.

167 atalytic domain, and this autoinhibition can be relieved by phosphorylation at Tyr369.

168 s that tethering of cross-bridges by cMyBP-C is relieved by phosphorylation of PKA sites in cMyBP-C,

169 TRIM28-mediated repression of STAT3 is relieved by phosphorylation of S473, and in vitro kin

170 This repression is relieved by phosphorylation of the N-terminal region

171 ates can inhibit kinase activation, and this is relieved by phosphorylation of these substrates by th

172 bition of transport substrate affinity, that is relieved by phosphorylation).

173 Na(+)(o) inhibition of HERG current was relieved by physiological [K(+)](o), while Na(+)(o)

174 s [Na]i affinity, and this inhibitory effect is relieved by PKA activation.

175 ts as an inhibitory constraint on I-LTP that is relieved by PKA.

176 its apparent Na(+) affinity, an effect that is relieved by PLM phosphorylation.

177 e but show that the requirement for clpX can be relieved by point mutations, frame shifts, or deletio

178 ddition, suppression of CTGF mRNA expression is relieved by pretreatment with an antagonist of PPAR g

179 NaC by affecting channel gating, which could be relieved by proteases cleavage.

180 cis-acting autoinhibitory domains, which can be relieved by protein kinase-mediated phosphorylation o

181 Channel block was relieved by pyrophosphate (5 mM) and ATP (5 mM), two

182 PA leads to reduced TCA cycle activity that is relieved by PZ-3022, providing preclinical proof of c

183 d54 contains an autoinhibitory activity that is relieved by Rad51.

184 Auto-inhibition is relieved by recognition of two template features, the

185 nts, Drosophila and mammals; this repression is relieved by reducing copy number, leading to chromati

186 complex and a block in transcription, which is relieved by removal of Leo1 or Rtf1.

187 where the inhibited state of the holoenzyme is relieved by removal of sigmaN Region I sequences.

188 Pairing-sensitive silencing is relieved by removing the transvection protein Zeste,

189 26, has the unusual property that inhibition is relieved by repeated short depolarizations.

190 se use-dependence," whereby inhibition could be relieved by repetitive depolarizations, a property se

191 "reverse use dependence", whereby inhibition was relieved by repetitive short depolarizations.

192 Additional distortion is relieved by retraction of filaments into the discs, w

193 two adjacent equatorial positions, and these are relieved by rotation toward the eclipsed conformatio

194 elated sigma factor and that this inhibition is relieved by RsrA binding, reaffirming that region 2 i

195 ucleotide biosynthesis, creating stress that is relieved by scavenged nucleotides.

196 Itch is relieved by scratching, but the neural mechanisms tha

197 y through a substrate-directed effect, which is relieved by Ser-301 phosphorylation.

198 This repression is relieved by shortening day length resulting in up-reg

199 The checkpoint function of NCoR is relieved by signal-dependent phosphorylation of c-Jun

200 nucleotide biosynthesis, and this inhibition was relieved by single amino acid replacements in IMP de

201 modification of GCDH lysine residues and can be relieved by SIRT5 deacylation activity.

202 Accordingly, repression is relieved by small in-frame insertions before this sec

203 ication-stressed Pif1-deficient cells, which was relieved by spontaneous mutations that eliminated th

204 essed protein level in normoxic cells, which was relieved by stimulation with hypoxia, cobaltous ions

205 promoter with tandemly linked GAS motifs can be relieved by strengthening the avidity of protein-DNA

206 ence and a slowing of channel activation and is relieved by strong depolarization resulting in facili

207 La3+ block was relieved by strong depolarization in a time- and vol

208 This inhibition was relieved by strong depolarizing prepulses.

209 rc/suprasubduction-zone ophiolite obduction, is relieved by subduction polarity reversal (flip).

210 ed signal, this dynamic range constraint can be relieved by subtracting away components of the signal

211 a-butyrolactone, and its repressing function is relieved by succinate semialdehyde (SSA).

212 Toxicity is relieved by supplementing the growth media with ribos

213 eurally mediated vasoconstriction, which can be relieved by systemic NOS inhibition with L-NMMA.

214 fore the G1/S restriction point, by p16INK4a is relieved by Tax.

215 Inhibition of delta-toxin deformylation was relieved by TCA cycle inactivation or by addition of

216 This inhibition is relieved by TGF- beta signalling, to which the future

217 eta repression of the SMA enhancer could not be relieved by TGFbeta1, whereas repression mediated by

218 interactions with the remainder of TelA that are relieved by the binding of divalent metal ions.

219 o the MUN domain and that these interactions are relieved by the RIM2alpha ZF domain and calmodulin,

220 The effect of the boronic acids could be relieved by the addition of boron-complexing sugars a

221 on protein A from M. thermoautotrophicum can be relieved by the addition of M. thermoautotrophicum ho

222 The defect could be relieved by the addition of magnesium to the swarm pl

223 n linked to the loss of ELO3 activities, can be relieved by the addition of metabolic sugars in the g

224 iated inhibition of the HCV IRES is shown to be relieved by the addition of recombinant human PTB in

225 The inhibition of Smo by Ptc can be relieved by the addition of Shh.

226 The thiamin requirement can be relieved by the addition of the thiamin precursor 5-h

227 ition of human and yeast cytosolic Hsp90 can be relieved by the cochaperone aha1.

228 atory suppression of fAbeta phagocytosis can be relieved by the coincubation with anti-inflammatory c

229 ion in a transient assay, and repression can be relieved by the deacetylase inhibitor trichostatin A

230 This repressive activity can be relieved by the HDAC inhibitor trichostatin A.

231 criptional repressor QS, and suppression can be relieved by the nontoxic small molecule quinic acid.

232 ost, but not all, such elongation blocks can be relieved by the re-addition of GTP.

233 ble epilepsy that is associated with HME can be relieved by the surgical treatment hemispherectomy, a

234 the tethered head of wild-type kinesin have been relieved by the long insertions.

235 The inherent repression of the 20S CP is relieved by the ATP-independent activators 11S and Bl

236 Autoinhibition is relieved by the binding of Ca(2+)-calmodulin to the c

237 This inhibition is relieved by the binding of the C-terminal region of c

238 abilize a distorted state of polymerase that is relieved by the binding of the two nucleotides requir

239 Transcriptional repression in vivo is relieved by the deacetylase inhibitor trichostatin A,

240 We show that this autoinhibition is relieved by the extracellular core domain of the tran

241 This inhibitory effect is relieved by the H3 tail, enabling recognition of flan

242 anscriptional repression by NK-3 and Groucho is relieved by the histone deacetylase inhibitor trichos

243 h is required for activation when repression is relieved by the inductive signal.

244 s with hexamer formation, an inhibition that is relieved by the insertion of the 56-kDa species.

245 ne 3T3 fibroblasts, the block to HIV-1 entry is relieved by the introduction of human CD4 and CCR5 or

246 undergo premature replicative arrest, which is relieved by the loss of p53.

247 The resulting acyl enzyme intermediate is relieved by the nucleophilic attack of the side-chain

248 lding wherein PDI acts as a placeholder that is relieved by the pairing of cysteines caused by substr

249 ugh increasing oxidative stress, this effect is relieved by the presence of Mn2+.

250 impose a replication fork pause, and pausing is relieved by the Rrm3p helicase.

251 s signal-peptide binding, but autoinhibition is relieved by the SecB chaperone.

252 This "stalled" UPR is relieved by the subsequent activation of compensatory

253 and inhibits translation, an inhibition that is relieved by the substrate acetyl-CoA.

254 ritical evidence of ER stress, which in turn is relieved by the UPR.

255 , resulting in an azimuthal compression that is relieved by the wrinkling of the entire sheet.

256 d with a decrease in oxygen availability and was relieved by the addition of nitrate.

257 this gene was restored when self-inhibition was relieved by the addition of plant surface waxes.

258 ition of DNA repair by the C terminus of p21 was relieved by the addition of purified PCNA protein.

259 tion in vitro by an excess of Fos-Jun dimers was relieved by the addition of TFIIE, indicating that i

260 endothelial cell growth, and this inhibition was relieved by the coaddition of either MMP inhibitors,

261 re of RUNX1c to allow nuclear colocalization was relieved by the deletion of amino-terminal residues

262 the occurrence of anaphylactic shock, which was relieved by the intramuscular injection of adrenalin

263 n, the growth defect of the DeltayopM mutant was relieved by the parent Y. pestis strain in a coinfec

264 matin template, however, and this repression was relieved by the phospho (Ser133) KID-dependent recru

265 This inhibition was relieved by the presence of a TR domain, which conta

266 ant mechanism by which mitral valve stenosis is relieved by this technique, and thus commissural morp

267 after infection by NRs, with this repression being relieved by titration of these repressors through

268 ntaneous insulin insensitivity, which cannot be relieved by TOPOBOP treatment.

269 ceptor can undergo self-squelching, and this was relieved by transfected c-Jun.

270 The repression of the promoter activity was relieved by treatment with DNA methyltransferase inh

271 This inhibition was relieved by treatment with estradiol but not by trea

272 The former effect of insulin was relieved by treatment with inhibitors of phosphatidy

273 This repression was relieved by treatment with the histone deacetylase i

274 Transciptional repression of targeted genes was relieved by treatment with the methyltransferase inh

275 ssors to suppress TrkA expression, which can be relieved by trichostatin A, an HDAC inhibitor.

276 Repression could be relieved by trichostatin A.

277 related Vav isozymes, auto-inhibition of Tim is relieved by truncation, mutation, or phosphorylation

278 This silence is relieved by TSA but not by RA.

279 Ume6p repression is relieved by ubiquitin-mediated destruction that is st

280 and school age children living with HIV may be relieved by use of long-acting formulations, but the

281 ginal activity by T3Rbeta and the repression is relieved by usp/T3Rbeta heterodimers.