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1 e the most frequent antibiotics the isolates were resistant to.
6 aracterized an ovarian cancer cell line that is resistant to a previously studied compound [Re(CO)(3)
7 Thirty-four percent of all blood isolates were resistant to a first-line antibiotic, and 1,397 (56
10 susceptible, and Blimp1-deficient Treg cells are resistant, to acquiring the ST2(+) Treg-cell phenoty
11 en display substantial in-vitro activity but are resistant to activation by ICLR recruitment factor S
13 transitioned into a metastable oligomer that was resistant to aggregation and only over extended time
15 roblast growth factor 21 and adiponectin and were resistant to alcohol-induced adipose atrophy and li
16 cts young individuals of African descent and is resistant to all targeted agents used to treat other
17 ial classes tested for, and a single isolate was resistant to all antibiotics tested for in the study
20 ns for infections caused by enterococci that are resistant to ampicillin and vancomycin, such as vanc
23 and fruits showed that the transgenic lines were resistant to anthracnose disease-causing C. gloeosp
25 a wall-deficient L-form state in which they are resistant to antibiotics that target cell wall synth
27 wild-type (WT) mice, OPN knockout (KO) mice were resistant to antibody-mediated PMN-dependent TRALI
29 ts and senescent myofibroblasts, rather than being resistant to apoptosis, are actually primed for ap
30 ion of an abnormal fibroblast phenotype that is resistant to apoptosis, degrades normal stromal matri
35 are polymerized to create coatings found to be resistant to biofilm formation by six different bacte
36 which likely adopted compact structures that are resistant to both charge migration and unfolding.
37 extensive and complex microenvironment, and is resistant to both chemotherapy and immune checkpoint
38 AF(V600E)-positive melanoma cells evolved to be resistant to BRAF and/or MEK1/2 inhibitors, combined
39 In contrast to the wild-type phage, which is resistant to BREX defence, T7 lacking Ocr is strongly
40 mmadelta T cells poised for IL-17 production were resistant to C. difficile infection, whereas elimin
42 proliferation of two cancer cell lines that are resistant to cancer drugs and diminished ERK signali
44 re living coral cover is high, are likely to be resistant to carbon dioxide-induced reef dissolution.
48 tic leukemia who experience relapse after or are resistant to CD19-targeted immunotherapies have limi
50 s highest in Pakistan (50%) as many isolates were resistant to cephalosporins, which were commonly pr
51 ctive coding models include predictions that are resistant to change, and these stubborn predictions
52 which helps explaining why chronic pain can be resistant to change, and where clinical characteristi
53 range of temperature and pH values, and they are resistant to chemical denaturation and proteolysis.
61 ion state analogs ADP.AlF(X) and ADP.MgF(X), being resistant to competitor nucleosome over a 24-h per
62 is characterized by recurrent seizures that are resistant to conventional anticonvulsant treatment b
63 ious work has shown that functional amyloids are resistant to conventional chemical denaturants, but
64 nsitive, whereas unfavorable histology WTPDX are resistant to conventional chemotherapy with vincrist
65 of triple negative breast cancer cells that are resistant to conventional chemotherapy, with just on
66 nst heterogeneous multiple myeloma (MM) that is resistant to conventional CAR-T cell therapy targetin
68 s are able to escape immune surveillance and are resistant to current treatment in immunotherapy.
69 egies to target HER2+ and EGFR+ cancers that are resistant to currently available mechanism-based age
71 ndogenous GUG-encoded DAP5 (eIF4G2/p97) mRNA is resistant to cycloheximide (CHX), a translation inhib
73 1(-/-) and DR6(-/-), but not Wld(s) neurons, are resistant to degeneration induced by conditioned med
77 substitutions and distinguished several that were resistant to degradation when expressed in both pla
85 found that highly connected glycan clusters are resistant to digestion and help stabilize the prefus
87 estimated that the proposed alcohol products were resistant to direct oxidation at 2.5 V/SHE, and the
89 ing surface is highly flexible, whereas they are resistant to diverging in color composition, presuma
90 y dense chromatin-containing structures that are resistant to DNase and exclude the general transcrip
93 onism and hypertension, even when the latter is resistant to drug treatment, strategies to screen pat
94 espite normal T cell priming, Sb1 (-/-) mice are resistant to EAE with a paucity of T helper (T(H)) c
95 bacterial and viral pathogens, EHV1 virions were resistant to eBDs through the action of the viral g
97 we show that mice lacking gammadelta-T cells are resistant to ECM when infected with Plasmodium bergh
98 hods revealed that the xylem of both species was resistant to embolism formation, with 50% of emboliz
99 ted by germline-derived DNA methylation that is resistant to embryonic reprogramming, resulting in pa
102 in menthol-sensitive Vglut3(lineage) neurons were resistant to entry into slow inactivation compared
104 ble patients, 386 had full DST, of which 246 were resistant to ethambutol and 217 were resistant to p
106 the visual sensory retinal ganglion neurons were resistant to excitability changes in age-matched SO
107 , we introduce a quencher-free approach that is resistant to false-positive signals, overcoming limit
108 Our work will aid in testing whether viruses are resistant to favipiravir and may help demonstrate th
109 Cancer cells with high basal AMPK activation are resistant to ferroptosis and AMPK inactivation sensi
112 cells and MCF-7 cells transduced with FGFR1 were resistant to fulvestrant +/- ribociclib or palbocic
113 emonstrated that one-third of primary T-ALLs were resistant to GCs when cells were cultured in the pr
115 ipotent stem cells (hPSCs), a cell type that is resistant to genome editing and in which modification
116 uman- and tupaia-derived primary hepatocytes were resistant to hepatitis D viruses pseudotyped with C
117 ic studies revealed that germ-free zebrafish are resistant to high fat diet induced EEC silencing.
119 we show that cells from the engineered pigs are resistant to human humoral rejection, cell-mediated
121 , are reported along with the finding that 1 is resistant to hydrolysis by all four classes of beta-l
122 nulocytic myeloid-derived suppressor cells), is resistant to ICB, and contains a minority of macropha
124 Our analyses revealed that ApcMin/Min cells are resistant to IL-22 due to reduced expression of the
126 n by the V558Delta;V653A Kit double mutation were resistant to imatinib, while cabozantinib was more
129 ory treatment strategy for solid tumors that are resistant to immunotherapy alone; however, there is
130 mice with Treg-restricted deletion of TRAF6 were resistant to implanted tumors and displayed enhance
131 T377A and hKv3.1-T400A yielded channels that were resistant to inactivation, and as a result, they di
132 he extent to which protected areas worldwide are resistant to incursions of alien species remains poo
133 Cultured A5(+/-);Kras primary tumor cells were resistant to induction and inhibition of autophagy,
135 exposed to atovaquone, a known antimalarial, are resistant to infection by the malaria parasite Plasm
136 -derived macrophages (BMDMs) from I/LnJ mice were resistant to infection from multiple MNV strains wh
138 truct with extra copies of the acidic domain is resistant to inhibition by mutant p53 and efficiently
140 cerbated in areas where mosquito populations are resistant to insecticides used in bed nets, but no a
146 ans and mice with diet-induced obesity (DIO) are resistant to leptin because of poor permeability of
149 ore, mice with muscle-specific p300 knockout were resistant to LLC tumor-induced muscle wasting.
150 ite, there was minimal residual disease that was resistant to loss of MITF activity (termed MITF-inde
151 ed decreased fitness of R. equi strains that were resistant to macrolides, rifampin, or both, resulti
153 portance in term of food spoilage since they are resistant to many of the common methods of food pres
154 The melanized yeast Exophiala dermatitidis is resistant to many environmental stresses and is used
157 associated T cell-intrinsic dysfunction that is resistant to memory development even after Lm-mediate
158 ed mice with depletion of the gamma1 subunit are resistant to metformin suppression of liver glucose
161 stability and showed efficacy in models that were resistant to microtubule inhibitors used as part of
164 ncreatic ductal adenocarcinoma (PDAC), which is resistant to most therapies including ICB(4), mutatio
167 d and hospital-associated MRSA strains which are resistant to multiple drugs including vancomycin and
168 aim of this study was to determine why mice are resistant to NASH development and the involvement of
170 esistant Staphylococcus aureus (MRSA), which is resistant to nearly all beta-lactam antibiotics, limi
171 e YAP activity of the different YAP1 fusions is resistant to negative Hippo pathway regulation due to
173 affect sensitivity to nintedanib, RET(L881V) was resistant to nintedanib analogs lacking a phenyl gro
176 e response to overfeeding of individuals who are "resistant" to obesity with those who are obesity pr
177 nd, when fed a high-fat and high-sugar diet, are resistant to obesity, hypercholesterolaemia, hyperte
178 Nevertheless, the vaccinated gBT-I.1 mice were resistant to ocular challenge with HSV-1 compared t
179 ential, form dentin pulp-like complexes, and are resistant to oncogenic transformation when compared
180 The increased prevalence of pathogens that are resistant to one or more classes of available medici
185 years or older) with polycythaemia vera who were resistant to or intolerant of hydroxyurea were rand
188 o transport active ingredients and that they are resistant to oral and gastric conditions that were t
189 wn Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be eval
193 We further found that non-AUG translation is resistant to other inhibitors that target ribosomes w
196 pulations frequently include phenotypes that are resistant to parasitism by hymenopterous parasitoid
197 dy, we demonstrate that IL-12-primed T cells are resistant to PD-1/PD-L1-mediated suppression and ret
200 (R5) coreceptors, we generated viruses that are resistant to peptide fusion inhibitors corresponding
201 urther, the enhancement of the ASIC currents was resistant to pertussis toxin treatment, suggesting t
202 t-namely, those with non-AUG start codons-to be resistant to pharmacological translation inhibitors a
205 that salivary gland cancer stem cells (CSCs) are resistant to platinum-based chemotherapy and drive t
206 mutant melanoma cell line, SB-3123(p) which is resistant to Pmel-1-directed ACT due to low gp100 exp
212 cumenting that 4E-BP1-overexpressing neurons are resistant to proteotoxic stress elicited by brefeldi
213 Notably, we found that TARK1 CRISPR plants were resistant to Pseudomonas syringae pathovar tomato s
214 ntriguingly, although wild-type C57Bl/6 mice are resistant to puromycin aminonucleoside (PA)-induced
216 ya in 2017, in an area where primary vectors are resistant to pyrethroids but susceptible to the IRS
218 R1881 treatment, yet ASCL1/hASH1 expression was resistant to R1881 treatment and hASH1 nuclear local
219 Cowpea (Vigna unguiculata) cultivar B301 is resistant to races SG4 and SG3 of the root parasitic
221 1 gene expression early during infection and were resistant to reactivation by vorinostat and interle
224 Xa (FXa) bound in the prothrombinase complex is resistant to regulation by protein protease inhibitor
226 ; the inert oxo-caps that provide solubility are resistant to replacement or further connectivity.
228 natal pups, late gestation fetuses proved to be resistant to rhesus rotavirus (RRV) mediated liver in
230 esults confirmed that the RRMS vs. SPMS test is resistant to sample-handling variations and can disti
232 antly, mice that controlled a live infection were resistant to secondary challenge and vaccination wi
233 l-like receptor 2-deficient (TLR2(-/-)) mice are resistant to septicemic infection by the KIM5 strain
234 hereas the majority of tier 2/3 Env proteins are resistant to SERINC5, when viruses are produced from
240 s that activated their meiotic genes in mice were resistant to specific genotoxic stress compared to
241 inosa strains that lack cardiolipin synthase are resistant to sphingosine, both in vitro and in vivo
242 mice deficient for this p53 phosphorylation were resistant to spontaneous and induced tumorigenesis,
246 ersistently infected with DeltaORF5 MERS-CoV were resistant to superinfection by wildtype virus, like
248 196, beta9, beta30, beta57, and beta70) that are resistant to T1D among subjects with DQ4-, 5-, 6-, a
249 s(1-3), but a substantial subset of proteins are resistant to targeted degradation using existing app
250 of downregulating the IFN receptor and Ch25h were resistant to TEV uptake, TEV-induced pre-metastatic
252 nem-resistant Enterobacteriaceae(1-4), which are resistant to the antibiotic class of 'last resort'.
253 ronic models, however, activated fibroblasts are resistant to the antifibrotic effects of PGE2 due to
254 ion, we demonstrate that post-pregnancy MECs are resistant to the downstream molecular programs induc
256 ajor challenge, as more than 30% of patients are resistant to the first line of treatment (selective
257 s of fully MHC-mismatched cardiac allografts are resistant to the graft-prolonging effects of costimu
259 ted from urine of urgent care patients would be resistant to the empirically prescribed antibiotic re
261 eurotrophin receptor (p75(NTR)) were seen to be resistant to the SD-induced impairments in hippocampa
265 on in noradrenergic neurons, and Gal OX mice were resistant to the anxiogenic effect of optogenetic L
266 of myocardial stress, the cardioGRMRdKO mice were resistant to the cardiac remodeling, left ventricul
267 ing the p75 neurotrophin receptor (p75(NTR)) were resistant to the detrimental effects of SD on hippo
269 d human NRAS-mutant melanoma xenografts that were resistant to the MEK inhibitor (MEKi) PD0325901 in
270 nced pancreatic ductal adenocarcinoma (PDAC) is resistant to therapy, including immune checkpoint inh
275 and mortality, a growing patient population is resistant to these medications, while off-target side
277 MS to induce cytotoxicity and Aag(-/-) cells are resistant to this combination FK866 and MMS treatmen
282 tiviral autophagy-related 5 (Atg5) knockdown were resistant to toxicity from TNF, but sensitized to d
286 Polarity can shift during the cell cycle and is resistant to treatment with microtubule, actin or aux
288 that CD8+ and CD4+ effector T cells with T21 are resistant to Treg-mediated suppression, regardless o
291 tion in a mouse model of ischemic injury and were resistant to tumorigenic transformation both in vit
296 asma, transitional, and mature naive B cells were resistant to VACV infection, while memory B cells w
298 restricted through HLA-C, whose presentation is resistant to viral immunomodulation, and well-studied