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1 Global prevalence estimates for CKD would be substantially reduced.
2 s vaccines, the burden of this disease could be substantially reduced.
3 HLA-matched mobilized blood cell grafts can be substantially reduced.
4 ot accumulate unless flux through hydrolysis is substantially reduced.
5 even when the abundance of invasive species is substantially reduced.
6 and the number of F4/80-positive macrophages is substantially reduced.
7 ated CD83 gene but CD4(+) T cell development is substantially reduced.
8 to promote MutL-dependent activation of MutH is substantially reduced.
9 undary predicted from the deterministic case is substantially reduced.
10 umors but their ability to produce IFN-gamma is substantially reduced.
11 ce body weight and improve glucose tolerance is substantially reduced.
12 d lifetime, in which an initial burn-in loss is substantially reduced.
13 mes economically reasonable only if its cost is substantially reduced.
14 NO formation and nitrosylation of NO targets are substantially reduced.
15 mutant animals from a targeted ES cell clone are substantially reduced.
16 mproves, artifacts and quantification errors are substantially reduced.
17 ation of NK cells in IFNalphabetaR(-/-) mice was substantially reduced.
18 lity of ataxin-1[82Q]-A776 to induce disease was substantially reduced.
19 early loss of tyrosine-phosphorylated Stat6 was substantially reduced.
20 hile binding of E81A and E81K mutants to PnC was substantially reduced.
21 of disrespectful treatment during childbirth was substantially reduced.
22 ndance of GLUT4 protein, but not GLUT4 mRNA, was substantially reduced.
23 ent as the Foxo1(-/-) GC-Tfh cell population was substantially reduced.
24 NRP1 binding of an inactive mutant of LD22-4 was substantially reduced.
25 the cost and time associated with each scan were substantially reduced.
26 (HP1) in the promoter regions of these genes were substantially reduced.
27 n of FAK on Tyr-397 and Tyr-576, and p130Cas were substantially reduced.
28 R current density and GluR1 expression level were substantially reduced.
29 t the differences in rates among the strains were substantially reduced.
30 rent ischemia, and urgent revascularization, were substantially reduced.
31 alities in coverage, mortality, and stunting were substantially reduced.
32 ence persisted after treatment when symptoms were substantially reduced.
33 nd the glutathione peroxidases GPx1 and GPx4 being substantially reduced.
34 ulent bacterial burden of vaccinated animals was substantially reduced (0.002%) compared to naive con
36 within two growing seasons, worker abundance was substantially reduced across the entire sampling are
37 ly since 1996, abundance of sediment infauna was substantially reduced across the sampled depth range
39 1(+/-) mutants, and dental epithelial growth is substantially reduced after the bud to cap stage tran
41 thnic differences were still significant but were substantially reduced after accounting for differen
42 tment for covariates, but these associations were substantially reduced after exclusion of participan
43 ported no coffee consumption, the risk of MS was substantially reduced among those who reported a hig
44 Errors due to stray light and dark counts are substantially reduced and fluctuations in pump inten
45 past 15 years, the prevalence of malaria has been substantially reduced and virus outbreaks have been
46 ssion of coronary atherosclerosis when LDL-C is substantially reduced and HDL-C is increased by more
47 tion of the ceramide moiety of sphingolipids is substantially reduced and their fatty acid compositio
48 Denervation- and tumor-induced muscle loss were substantially reduced and survival rates improved b
49 ts on neuronal responses and synchrony in V4 were substantially reduced and the remaining effects of
51 ge tumors where the penetration of light can be substantially reduced, and the intra-tumoral nanopart
52 and urban development, malaria transmission is substantially reduced, and risks of new infection are
53 Ca(2+) store-refilling rate in STIM1-KO SMCs was substantially reduced, and sustained PDGF-induced Ca
54 ized, activated partial thromboplastin times were substantially reduced, and anti-cFIX was not detect
55 he electron scavenger the yield of 8-oxo-G*+ is substantially reduced as a result of electron recombi
57 between myofibroblasts and keratocytes, but was substantially reduced as a percentage of total water
59 e key regulators of T lineage specification, is substantially reduced, as are functional thymic proge
61 o predictions from theory, and the potential is substantially reduced at higher salt, also as predict
64 with an intentional smallpox outbreak would be substantially reduced because of pre-existing immunit
65 nnual mortality among oldest-old individuals was substantially reduced between 0.2% and 1.3% in 1998-
66 for the FabI mutants G93V, M159T, and F203L is substantially reduced, binding preferentially to the
67 rsus 2.4%, log rank P<0.0001), findings that were substantially reduced but persisted after propensit
69 disorganized and the number of retinal axons was substantially reduced, but the few remaining axons n
70 The microstrabismic subjects' stereoacuities were substantially reduced, but their discrimination res
71 fects of form deprivation in infant primates are substantially reduced by relatively short daily peri
72 studied species, thermal and hypoxic limits are substantially reduced by the energetic demands of ec
73 cytosis across the mouse blood-brain barrier are substantially reduced by the high beta sheet content
74 n, and the findings suggest that risks could be substantially reduced by achieving a 1.5 degrees C ta
76 emonstrates that defibrillation energies can be substantially reduced by applying discrete stimulatio
79 e viability of the population is unlikely to be substantially reduced by genetic factors in the next
80 ata, the number of compatible haplotypes can be substantially reduced by HAPLORE, and the program wil
83 levels in several organs including liver can be substantially reduced by selenium deficiency without
84 special type of visually evoked movement can be substantially reduced by startling sound, even though
85 fect of adjuvant breast cancer treatment can be substantially reduced by the addition of denosumab, t
86 he recently introduced cryogenic probes, can be substantially reduced by the electrical noise generat
87 ificantly, the processivity of translocation is substantially reduced by approximately 25- and 6-fold
88 cadal periods of enhanced hurricane activity is substantially reduced by GHG forcing, which allows hu
89 albuminuria observed when single-nephron GFR is substantially reduced by severe pathological decrease
90 Here, we observed that this immunogenicity is substantially reduced by substituting six residues wi
91 e indicates nanosecond dynamic disorder that is substantially reduced by TFE, but a significant gradi
92 the emerging view that CFTR channel activity is substantially reduced by the deltaF508 mutation and t
94 he association between PMCA4b and GPER/GPR30 is substantially reduced by truncation of either or both
95 terscan variability of multi-detector row CT is substantially reduced by using the calcium volume met
99 avage of semaphorin 7A and 12 other proteins was substantially reduced by an inhibitor of ADAM17, a k
102 ound that production of infectious AcMNPV BV was substantially reduced by expression of DN VPS4 but n
104 rast, basolateral to apical EBV transcytosis was substantially reduced by nystatin, an inhibitor of c
105 response to PLC-coupled receptor activation was substantially reduced by OAG or DAG-lipase inhibitio
107 use the activity of three of these enhancers was substantially reduced by point mutations in this are
110 l and ipsilateral neurons to a single target was substantially reduced by the presence of a distracte
111 ivity as measured by the factor of variation were substantially reduced by 9.7% (from 3.1 to 2.8) and
112 tic cells, resulting CD4(+) T cell responses were substantially reduced by Ab blockade of OX40L and,
113 to heart failure therapies, but PVCs and DCM were substantially reduced by amiodarone or flecainide,
114 findings, which are characteristic of FSGS, were substantially reduced by depleting CD4+ T cells fro
116 and sea-level rise in the twentieth century were substantially reduced by the colossal eruption in 1
117 ectionally selective responses in these RGCs were substantially reduced by the selective group II mGl
118 ells in recipients injected with PTX and HEL were substantially reduced by treatment with Abs against
119 1.3, whereas mean grating resolution acuity was substantially reduced, by a factor of 4.1, compared
120 ycoprotein expression and transport activity are substantially reduced compared with wild-type contro
122 e S layer of each of the spo0 mutant strains was substantially reduced compared to that of the parent
125 oliferation of thymocytes and mature T cells was substantially reduced compared with control mice.
127 mors, the expression of both INPP4B and PTEN was substantially reduced compared with normal tissue.
128 ther bone marrow or from peritoneal exudates was substantially reduced compared with that of wild typ
129 The termination field of individual axons was substantially reduced compared with that of younger
130 mulation of BST2 promoter activity by GATA1s was substantially reduced compared with the full-length
131 mice and showed that growth of these tumours was substantially reduced compared with wild-type litter
132 Viral infectivity, replication, and spread were substantially reduced compared to that of a control
133 ults, and both venous [ATP] and ATP effluent were substantially reduced compared with young people de
135 sk difference of 0.13%/year, the net benefit was substantially reduced (difference = 0.001 QALYs).
136 HIP-deficient cells, SirT6 protein half-life is substantially reduced due to increased proteasome-med
140 t on velocity, but the gain of this function was substantially reduced during CAR and WORLD, again as
141 stem were intense as the community diversity was substantially reduced during the treatment steps.
143 of axons that regrow beyond the injury site is substantially reduced, even when the tumor suppressor
144 We have found that the hepatic energy state is substantially reduced following exercise, fasting, an
145 timulated in response to E30480 supernatants was substantially reduced following pretreatment with an
146 requires an intact (d)ATP-binding pocket and is substantially reduced for most CAPS-associated NLRP3
149 ospitalization rates after bariatric surgery were substantially reduced for all-cause (361 vs 501 per
150 n Crry(-/-)C3(+/-) and Crry(-/-)fB(+/-) mice were substantially reduced for gene dosage secondary to
151 00 insertion mutants yielded 18 mutants that were substantially reduced for SOS induction following n
153 nd spatial restrictions of this approach can be substantially reduced if an appropriate sorbent is in
154 mesenteric arteries have Kir currents, which are substantially reduced in EC-specific Kir2.1 knockdow
155 antly, levels of KLF5 transcript and protein are substantially reduced in H-Ras-transformed cells tre
157 , and acetyl-CoA carboxylase phosphorylation are substantially reduced in HeLa cells transfected with
158 In contrast, primary afferent-evoked IPSCs are substantially reduced in incidence, magnitude, and d
159 stin and of the glucosidase II alpha subunit are substantially reduced in liver and Epstein-Barr viru
160 mpal kainic acid administration to mice, and are substantially reduced in mice overexpressing human C
162 boxylase 67 (GAD67) mRNAs and protein levels are substantially reduced in postmortem brains of patien
163 ting, splicing, and translation of HAC1 mRNA are substantially reduced in the kin1Delta kin2Delta str
166 ansfusion requirements have been reported to be substantially reduced in some patients who receive ac
168 ectra show that the structural heterogeneity is substantially reduced in ap7 and ap19 as compared to
169 r, phosphorylation of STAT-1 at tyrosine 701 is substantially reduced in both IFN-gamma-treated human
171 ensitivity and that viral genome methylation is substantially reduced in drb3 compared to wild-type p
172 ex association with SAGA-dependent promoters is substantially reduced in gal11/med15Delta med3Delta y
173 etic marker found at high levels in neurons, is substantially reduced in human ataxia-telangiectasia
174 estingly, though IgG autoantibody production is substantially reduced in Icos(-/-) MRL(lpr) mice, the
175 sandman expression on cortex glial membranes is substantially reduced in NCKX(zydeco) mutants, indica
178 that the functional glycosylation of alphaDG is substantially reduced in prostate cancer metastases.
185 apacity of ROS generation induced by arsenic is substantially reduced in the transformed cells relati
186 reveals that the structural relaxation time is substantially reduced in these adaptive liquids, and
191 rrent in myotubes homozygous for RyR1-E4242G was substantially reduced in amplitude ( approximately 8
192 ellular signal-regulated kinase 1/2 (ERK1/2) was substantially reduced in association with protein ag
193 Interestingly, the fragmentation phenotype was substantially reduced in atpat21-1 spo11-1 double mu
195 Supporting this concept, eHEV infectivity was substantially reduced in cells depleted of Niemann-P
196 Furthermore, forskolin's protective effect was substantially reduced in CGN cultures genetically de
197 tion in conditions of low visual load, which was substantially reduced in conditions of high visual l
198 t the expansion of LCMV-specific CD8 T cells was substantially reduced in EGR1-/- mice, as compared w
199 accuracy of the population code for position was substantially reduced in GluA1(-)/(-), yet it is pre
200 lveolar lavage fluid content of MIP-2 and KC was substantially reduced in lpr mice after lung injury
202 ted of CD20(+) B cells, whereas inflammation was substantially reduced in mice with hyperactive B cel
203 condary, but not the primary, response to Ag was substantially reduced in mice, which received iNOS i
205 Postsynaptic GluK2/3 Immunogold labeling was substantially reduced in Neto-null mice compared wit
207 ed in rho(0) cells, AP endonuclease activity was substantially reduced in nuclear and in whole cell e
210 howed that colonic epithelial VDR expression was substantially reduced in patients with Crohn's disea
212 h encodes beta-arrestin1 (a GLI1 inhibitor), was substantially reduced in proliferating and, to a les
216 -threonine kinase Akt, which activates eNOS, was substantially reduced in sinusoidal endothelial cell
217 nduced mitochondrial permeability transition was substantially reduced in spinal cord vs. neocortex a
218 predominantly Tspan33, and ADAM10 expression was substantially reduced in the absence of this tetrasp
221 lcytosine dioxygenase TET1 (TET1) expression was substantially reduced in the ethanol-fed rats and wa
223 Notably, we found that Foxo1 expression was substantially reduced in the LY6D(-) HEB- and E2A-de
224 es cerevisiae beta-glucan by RAW macrophages was substantially reduced in the presence of cytochalasi
226 te caused an increase in fluorescence, which was substantially reduced in the presence of the antioxi
227 e mutant PI3K as well as AKT phosphorylation was substantially reduced in the Ron knockdown cells com
228 plication, the steady-state level of HBV DNA was substantially reduced in the UBP43-deficient mice in
230 ZQ administration in infected wild-type mice was substantially reduced in treated C3-deficient mice,
232 ion, NAAG-immunoreactive fibers and synapses were substantially reduced in all contralateral retinal
234 c lesions of proximal aortas and aortic tree were substantially reduced in ApoE+/-/IL-1R1-/- mice tha
235 iate-early genes and viral plaque formation) were substantially reduced in cells transfected with dom
236 re reversed by BDNF, concentrations of which were substantially reduced in hippocampus of both Hdh(Q9
239 e levels of SHP-1 and its enzymatic activity were substantially reduced in multiple organs from alpha
240 erythroid progenitor cells and reticulocytes were substantially reduced in number in mice lacking HIF
243 oneal leukocyte recruitment and accumulation were substantially reduced in Rock1(+/-) mice compared w
244 ponses and spontaneous pain behavior in vivo were substantially reduced in S1P(3)(-/-) mice, whereas
245 mia on the distribution of Na(+),K(+)-ATPase were substantially reduced in the epithelial cells of di
246 PVN, concentrations of TRH in the PVN and ME were substantially reduced in the fasted animals relativ
247 e absence of IL-5, IL-13-triggered responses were substantially reduced in the granulomatous tissues.
248 n, STAT5 activation and cyclin D1 expression were substantially reduced in the mammary epithelium of
249 nous expression and reporter gene expression were substantially reduced in the presence of I-dsRNA.
250 r and the fraction of theta-rhythmic neurons were substantially reduced in the ventral compared with
251 ponses and cellular responses to alloantigen were substantially reduced in TP(-/-) spleen cells.
253 ion of Thorase, the internalization of AMPAR is substantially reduced, leading to increased amplitude
254 ty was not affected but viral DNA production was substantially reduced, neither the amount of HBV tra
256 , and cell surface and total HLA-DR proteins were substantially reduced on a continuing basis after i
258 otency of the linear peptide agonist NDP-MSH were substantially reduced only in D126A and H264A mutan
259 er, these complex context dependencies could be substantially reduced or eliminated by rescaling clim
264 in peripheral neurons, where gene expression is substantially reduced relative to that in productive
265 ze of the annual terrestrial carbon sink may be substantially reduced, resulting in a positive feedba
267 a mutant hearts levels of phosphorylated NF2 are substantially reduced, suggesting an impairment of H
268 positive neurons in the lateral hypothalamus are substantially reduced, suggesting that some of the c
269 ist even after soluble alpha-syn levels have been substantially reduced, suggesting that once formed,
270 quirement for SsrB in activating SPI-2 genes is substantially reduced, suggesting a role for SsrB in
272 cts showed that the energy requirement could be substantially reduced to 0.90 kWh/m(3) and $0.058/kg
273 l, however, disease incidence is expected to be substantially reduced under both scenarios and remain
274 on isolated platelets, however, its activity was substantially reduced under physiological conditions
275 mplicated in hepatic steatosis and fibrosis, was substantially reduced upon deletion of Epac1/2, whil
277 ma cells lacking either or both MIF and D-DT are substantially reduced when compared with normal supe
278 ion against inflammatory bowel disease could be substantially reduced when stable beta-catenin-expres
279 we tested whether variation in CBR data can be substantially reduced when using an improved experime
281 uitment of mast cell progenitors to the lung is substantially reduced when CD11c(+) cells are deplete
282 conditions, their effectiveness as catalysts is substantially reduced when substrates are poorly wate
283 e within the ciliary processes of these eyes was substantially reduced when compared with the 20-minu
284 ath caused by rPrP fibrils or beta-oligomers was substantially reduced when expression of endogenous
285 on of Sox17alpha and HNF1beta by GATA4 and 5 was substantially reduced when protein synthesis was inh
286 dy 4, the strength of the signature response was substantially reduced when remifentanil was administ
288 l of the nNOS promoter, and this stimulation was substantially reduced when the two CREs were mutated
289 accumulation in the Ad-Stat-EVA treated mice were substantially reduced when compared with values in
292 monstrated that the fraction of K63 linkages was substantially reduced, whereas relative amounts of m
293 urther, we show that off-target cleavage can be substantially reduced while maintaining robust editin
294 cing depth, and training population size can be substantially reduced with no significant impact on m
295 formation after uremic serum exposure, which was substantially reduced with the prior treatment with
296 s, histologic lesions were still present but were substantially reduced with prior depletion of macro
297 t within- and between-platform artefacts can be substantially reduced, with concomitant improvement i
298 are not independent in the population, bias is substantially reduced, with a corresponding reduction
299 g rates of Purkinje neurons from mutant mice were substantially reduced, with no effect on threshold