ライフサイエンスコーパス: be unable to

1 ffer from having serious adverse effects and are unable to abolish the virus from the host.

2 ocesses, yet conventional imaging modalities are unable to access intricate biomolecular information

3 Cas proteins and restriction enzymes are unable to access the phage DNA throughout the infect

4 Classical capture models are unable to account for this pronounced inverse kineti

5 umber of compounds observed in our study, we are unable to account for ~20% of the carbon flow.

6 be, at least in part, the result of females being unable to accumulate the energy reserves necessary

7 ractions between adsorbed species and, thus, are unable to accurately describe the formation of adsor

8 ia detection to guide revascularization have been unable to accurately predict treatment effects of C

9 Therefore, we were unable to accurately estimate the timing of each in

10 Thus, the applied taVNS device or protocol was unable to achieve significant effects on autonomic i

11 An NF2 mutant deficient in lipid binding is unable to activate the Hippo pathway in response to o

12 cells, while vaccine-elicited RM antibodies were unable to activate either human or RM NK cells.

13 atients also failed to generalize, i.e. they were unable to adopt analogous aiming strategies in resp

14 Zebrafish scospondin-null mutants are unable to assemble a Reissner fiber and fail to form

15 rived sequences in metagenomic data sets, we are unable to assign a function to 50-90% of genes, or m

16 of energy consumption, and explain why MCDI is unable to attain the performance of ED, even with ide

17 on, these promoters gain DNA methylation and are unable to be activated upon differentiation.

18 ny clinical isolates, both animal and human, are unable to be isolated and characterized, limiting ou

19 sites during human infection are asexual and are unable to be transmitted to mosquitoes.

20 Surprisingly, we observed that vDeltaUL47 was unable to be horizontally transmitted to naive chick

21 other targets had sensitivities of >=75% or were unable to be calculated due to low prevalence in th

22 cal ventilation for greater than 2 weeks who were unable to be extubated and determined to have reaso

23 eterohexamer into two heterotetramers, which are unable to bind the promoter DNA optimally due to ste

24 rates a TB19/TB38 biparatopic antibody would be unable to bind the CD73 dimer in a bivalent manner, i

25 The swapped form of Nck-SH3.1 is unable to bind CD3e, possibly representing an inactiv

26 ontrast, isolated FANCD2 is a homodimer that is unable to bind DNA, suggestive of an autoinhibitory m

27 is exclusively localized in the cytosol and is unable to bind DNA.

28 istently, an HO2 catalytic site variant that is unable to bind heme exhibits a constant low protein l

29 P were distinct and that an FMRP mutant that is unable to bind ribosomes still promoted localization

30 Phosphorylated SMAD4 is unable to bind to DNA and fails to elicit TGF-beta ge

31 Although it is unable to bind to or splice RNA, it forms abundant ag

32 Nedd8 conjugated VHL is unable to bind to p53 thereby preventing the inductio

33 BPV-1 Y102E was unable to bind E1 and did not replicate in a transie

34 ction by using knock-in of a mutant p27 that was unable to bind to Skp2.

35 ear, in particular since all D/N Vif mutants were unable to bind Cul5 and some mutants additionally f

36 parental CHIKV, the developed VLoop mutants were unable to block induction of type I interferon.

37 t of wastewater sensing, MESe technology has been unable to bridge the gap between the laboratory and

38 Mutant myotubes are unable to buffer the increase in membrane tension in

39 Consequently, single-scale models are unable to capture the critical cross-scale interacti

40 es, but due to their underlying design, they are unable to capture the full complexity of phage genom

41 ting models can be difficult to tune and may be unable to capture the dynamics of non-extracellular p

42 wild-type myoglobin, and other hemoproteins are unable to catalyze this reaction, the myoglobin scaf

43 FakA, as both hla and hla DeltafakA mutants are unable to cause necrosis of the skin.

44 LmCen(-/-) is safe since it is unable to cause disease in immunocompromised mice, in

45 HS069Deltacap was unable to cause signs of systemic disease during a p

46 typic interactions, which single-color tsMSQ is unable to characterize.

47 introduced in vivo, the bacteriophage switch is unable to choose the lytic life cycle showing that th

48 ice in a systemic model of HAT, the compound was unable to clear parasitemia in a CNS model of the di

49 interacts with Cas9, and Cas9-Acr complexes were unable to cleave DNA.

50 ch play a key role in priming Tfh responses, were unable to cluster to the interfollicular regions of

51 ganization, which leads to bulky valves that are unable to coapt correctly during ventricular systole

52 ozygous +/gpt1 plants demonstrated that GPT2 is unable to compensate for GPT1 in plastids, whereas GP

53 iver and extrahepatic tissues in obese-NAFLD is unable to compensate for the increase in insulin resi

54 ing that the mitochondrial metabolic network is unable to compensate when exposed to additional stres

55 bit reduced stability and missence mutations were unable to complement TMTC3 rescue of gastrulation i

56 We also observe that elongating ribosomes are unable to complete translation because they are bloc

57 resentation at 59.0% (95% CI, 51.6-65.9) and being unable to complete normal activities for 3 or more

58 ious rupture of the same Achilles tendon, or being unable to complete the questionnaires.

59 locked at different cell cycle stages and so were unable to complete the cell cycle, thus defining ge

60 ific, but current models of helping behavior are unable to completely parse apart whether the reporte

61 r of publications or journals published in - were unable to completely differentiate applicants with

62 tation, or (c) 3 or more consecutive days of being unable to conduct usual activity--yielded a sensit

63 e did not review grey literature and that we were unable to conduct moderation analyses for several p

64 We were unable to confirm a benefit of hydroxychloroquine o

65 However, we were unable to confirm that 3-MPA inhibited PEPCK-M enzy

66 Previous studies have been unable to constrain the location between possibilit

67 Despite extensive efforts, the journal was unable to contact Dr.

68 P expression in Foxp3(+) T(reg) cells, which are unable to control colitis in a cell-transfer model o

69 ly restrain bacteria growth, some granulomas are unable to control Mtb growth, leading to bacteria an

70 mortality in immune-deficient patients, who are unable to control viral dissemination.

71 ree mice or animals that receive antibiotics are unable to control viral replication within the brain

72 m is activated in an uncontrolled manner and is unable to control infection in a timely fashion.

73 re also found in gut bacterial isolates that are unable to convert choline to TMA, suggesting that ad

74 re changed to the ones present in CsGA1ox/ds was unable to convert GA(9) to GA(4), highlighting the i

75 ons that require a high level of flexibility are unable to coordinate without the introduction of add

76 RIPK1-deficient cells are unable to cope with energetic stress and are vulnera

77 is able to cleave galactosylsphingosine, and is unable to cross-correct.

78 drug regimens suppress HIV-1 replication but are unable to cure infection.

79 al for two FLT3 inhibitors, these modalities were unable to cure AML or significantly extend the live

80 s were sprayed with Fe in their leaves, they were unable to deactivate root Fe uptake.

81 ohol abuse in different male populations but were unable to define a mechanism.

82 is its observational nature, meaning that we are unable to definitively determine causality.

83 zation was absent in two MARCH6 mutants that are unable to degrade themselves, indicating that choles

84 series of solid tumors treated with ICB, we are unable to demonstrate favorable response to ICB in p

85 her in the underweight subgroups, this study was unable to demonstrate that nutritional status modifi

86 m radiotherapy is frequently recommended, we were unable to demonstrate any beneficial therapeutic ef

87 However, we were unable to demonstrate improved potency relative to

88 usion transmission if blood screening assays are unable to detect HIV in donations from infected dono

89 often requires labor-intensive surveys that are unable to detect rapid or unanticipated environmenta

90 Moreover, this antibody was unable to detect activated Rac1 in membrane ruffles

91 cancer was low (42.8%) because the technique was unable to detect capsular or vascular invasion, alth

92 Qualitative (18)F-FDG PET/CT was unable to detect TRG3-4 in 15% of patients.

93 Surprisingly, we were unable to detect any specific change in the express

94 tected few changes under most conditions and were unable to detect consistent changes across studies

95 ported to use sulfate for respiration but we were unable to detect DSR in these isolates.

96 Moreover, in one elite controller, we were unable to detect intact proviral sequences despite

97 on of QPSSSR has never been reported, and we were unable to detect it by traditional methods.

98 % relative to the spiked control brains), we were unable to detect the other individual ABX in brain

99 s the species' range; however, those studies were unable to determine the degree to which adaptive di

100 e main limitations of our study were that we were unable to determine why CA125 tests were performed

101 not enhanced in irradiated ASMKO mice, which are unable to develop intestinal failure injury.

102 By contrast, scientists have been unable to develop a physical measure linked to perc

103 andemly-arranged VTL4-VTL8 genes, named 13U, was unable to develop functional nodules and failed to f

104 In the absence of FAO, the progenitors are unable to differentiate and exhibit altered histone

105 Memory T cells are unable to differentiate into the Th2 phenotype, and

106 ive to each of these areas: (i) metabolomics is unable to differentiate whether a mutation has result

107 insulin-like growth factor-binding protein 7 was unable to differentiate transient from persistent ac

108 Bulk analytical techniques were unable to differentiate between inoculated samples

109 However, these studies were unable to differentiate the state of infection, i.e

110 logical and technical limitations, they have been unable to directly test the stress-reactivity hypot

111 iscriminants used for species identification are unable to discern hybrids, so molecular methods are

112 Neuroimaging studies in humans have thus far been unable to discern between these two models, though

113 y measure the total concentration of ALP but are unable to distinguish enzyme isotypes.

114 and 3500 Pa, whereas the standard DI output was unable to distinguish between these two groups of ce

115 est, P < 0.001), whereas CXR/MRI and CCT/MRI were unable to distinguish between these groups in terms

116 when faster or slower environmental changes are unable to do so.

117 algorithms or systems, which existing tools are unable to do.

118 ds suffer from high false-positive rates and are unable to effectively differentiate direct miRNA tar

119 larly where creeks exhibit morphologies that are unable to efficiently drain adjacent marsh platforms

120 ther demonstrated that cross-presenting pDCs were unable to efficiently prime CD8 T cells by themselv

121 Native luciferases were unable to efficiently process the analog, but a com

122 Thus, CD4-MBL CAR-T cells are unable to eliminate the FDC-associated HIV reservoir

123 As these defective proviruses are unable to encode intact and replication-competent vi

124 In lgo-2 mutant plants where cells are unable to endoreplicate fully, cotyledon organ size

125 IgG-containing ICs with an Fc engineered to be unable to engage FcRn did not.

126 ar injection, but many ophthalmic treatments are unable to enter the eye or reach the posterior segme

127 cs studies showed that the formate substrate was unable to enter the vestibule region of EcYfdC.

128 ma have effector function, the immune system is unable to eradicate the malignant clone.

129 While individuals seem to be unable to escape the fitness effects of their morphol

130 These previous studies, being correlative, were unable to establish any functional role for the fal

131 replication, and genomes with this mutation were unable to establish stable episomes in keratinocyte

132 fined using traditional group-level analyses was unable to estimate either baseline memory performanc

133 evidence of large reductions in SFA, but we are unable to exclude more modest benefits.

134 Both KHAP1 and KHAP2 null mutants are unable to execute cytokinesis but are able to traffi

135 de an enhanced recovery option for those who are unable to exercise after injury ABSTRACT: Chronic pa

136 remains unknown and may benefit patients who are unable to exercise as a result of immobilization.

137 Synaptotagmin VII, respectively, invadopodia were unable to expand and elongate.

138 two set-ups, I argue that these differences are unable to explain the lack of replication in Markel,

139 e-art models to describe adhesive properties are unable to explain these experimental observations, i

140 articles and collectors, and the DLVO theory was unable to explain the observed particle attachment.

141 eveal that unlike FFA4-S, the longer isoform is unable to facilitate phosphorylation of ERK1/2 in cel

142 To date, we are unable to find critical care specific literature on

143 For studies that were unable to find improvements in water quality after

144 caine-inactivated VLs had tortuous paths and were unable to find their nest, whereas ants from the un

145 rotein recruitment determines repair choice, are unable to fit the literature data.

146 Mutants are unable to form occlusive venous and arterial thrombi

147 tagged peptides and chimeric constructs that are unable to form the interclass 5-HT(2A)R-mGluR2 compl

148 actors are obligate dimers, and because ATF4 is unable to form highly-stable homodimers, we hypothesi

149 We developed a Brpt5.5 mutant that was unable to form the tetramer and was concordantly inc

150 an unpatterned clump of spherical cells that were unable to form gametophores, demonstrating that ROP

151 ly reduced growth and invasion in vitro, and were unable to form xenografted tumors.

152 om process and suffers from a low yield that is unable to fulfill the high-throughput analysis requir

153 xpression following cisplatin treatment, RPA is unable to fully protect ssDNA created by cisplatin ad

154 found that persistent local airborne inputs were unable to fully explain Antarctic soil community as

155 bound to the oolemma, TMEM95-deficient sperm were unable to fuse with the egg membrane or penetrate i

156 on signature marked by Sca1, but upon injury are unable to generate Sca-1(+)/Clu(+) revSCs and could

157 the mutant nicotinic acetylcholine receptors were unable to generate current following stimulation wi

158 The upp knockout mutants are unable to grow photoautotrophically, and knockdown m

159 Rv2509 homologue in Mycobacterium bovis BCG, was unable to grow following the conditional depletion o

160 Simulated trees were unable to grow roots rapidly enough to mediate the

161 freedom of (*)CH(3) shows that enzymes would be unable to harness this radical as a regio- and stereo

162 at displays normal cellular localization but is unable to hydrolyze cyclic GMP (cGMP).

163 A serum LDL-C cutoff of 100 mg/dL was unable to identify individuals at risk of a CVD even

164 tients who (1) first presented with GMG, (2) were unable to identify the time of onset of OMG or GMG,

165 3K9me3 in SCNT-derived blastocysts, but this was unable to improve their preimplantation development.

166 ive GSK3beta implies that phosphorylated AKT was unable to inactivate GSK3beta.

167 s a pronounced specificity for adenylate and is unable to incorporate guanylate into RNA products, wh

168 The truncated ssTnT is unable to incorporate into myofilament and is degrade

169 We were unable to incorporate a control arm due to logistic

170 ant, which no longer interacted with TRIM21, was unable to increase Nrf2-mediated transcriptional act

171 we found that these pairs of single stimuli are unable to induce any synaptic modification in 1.3 an

172 represent so-called "fake antigens," as they are unable to induce immunity, but may react with and cr

173 ynthesize inositol pyrophosphates (PP-InsPs) are unable to induce the ESR.

174 rmore, we find that in oocytes where Kinesin is unable to induce cytoplasmic streaming, the growth di

175 ., calreticulin, HSP70, and HMGB1); however, is unable to induce ICD.

176 like WT CLASP2, the CLASP2 C-terminal mutant is unable to induce MT stabilization or promote early HI

177 does not promote high-affinity DNA binding, is unable to induce the same allosteric response as nick

178 mutant infection in the genital tract alone was unable to induce any significant hydrosalpinx.

179 Interestingly, it was unable to induce excystation and increased trophozoi

180 of the JH receptor Methoprene tolerant (Met) was unable to induce Kr-h1 in the presence of HDAC1 or S

181 mediate the infection of human gut cells but is unable to infect human lung cells.

182 ild-type (WT) LIN28B or a LIN28B mutant that is unable to inhibit let-7 processing increases the pene

183 nontoxic doses, atorvastatin and mevastatin were unable to inhibit Mtb growth in THP-1 cells.

184 potential superinfectors are sequestered and are unable to initiate new infections.

185 nking by penicillin-binding protein 2 (PBP2) are unable to initiate polarized division, while cells t

186 ery likely (>90% probability) that mangroves were unable to initiate sustained accretion when RSLR ra

187 4A, we generated specific point mutants that are unable to interact with either condensin I or PRC1 o

188 Interestingly, CaMPK9 is unable to interact with CaWRKY40 when the relevant tw

189 cally, expression of a leiomodin mutant that is unable to interact with tropomyosin fails to displace

190 se infection clearance, but only if the drug is unable to interfere with infection of the first cells

191 Because in vivo experimental methods are unable to isolate or control individual factors of t

192 gs with IE were significantly more likely to be unable to learn the spatial discrimination task (p =

193 However, these indirect methods are unable to link networks to the hardwiring that under

194 The Authors were unable to locate the original films for all of thes

195 that parasites lacking the esophageal gland are unable to lyse ingested immune cells within the esop

196 chondria with disrupted inner membranes that are unable to maintain a proton gradient, while expellin

197 n both transfection and infection conditions was unable to maintain high episome copy numbers in epit

198 h prior to neutrophil addition, neutrophils were unable to maintain control of the nascent biofilm.

199 periods, the observed dynamics for all taxa were unable to maintain current community composition, h

200 When CD5 was conditionally ablated, T cells were unable to maintain higher expression of the cytopla

201 Important limitations include being unable to measure children's underlying health sta

202 Services, therefore, have been unable to meet the rising demand.

203 lymphocytes are completely pilot-less: they are unable to migrate toward chemokines despite their no

204 hoc2 exhibited reduced junction turnover and were unable to migrate effectively as a group.

205 One limitation to note is that we were unable to model for changes in multimorbidity durin

206 stalk-binding antibodies lacking NI activity were unable to neutralize viral infection via microneutr

207 Despite this, a Synechococcus strain was unable to outcompete a Prochlorococcus strain in co-

208 ents who were dependent (GOSE 3 or 4) or who were unable to participate in one or more major life act

209 nal antibodies, are structurally complex and are unable to penetrate the skin barrier.

210 Many laboratories are unable to perform colistin susceptibility testing.

211 ative infections, many clinical laboratories are unable to perform susceptibility testing due to the

212 ed equivalently to 3D4/31 cells; however, it was unable to persistently colonize the nasal cavity of

213 0RB-/- iPSCs lacked IL-10RB mRNA expression, were unable to phosphorylate STAT3, and failed to reduce

214 Finally, we show that MSL10 is unable to potentiate cell swelling-induced death when

215 sing magnetic resonance imaging (MRI), which is unable to precisely identify tumor cell invasion, imp

216 Additionally, they are unable to predict whether the drug-induced gene expr

217 The official forecast and computer models were unable to predict rapid intensification of these st

218 In C57BL/6 mice, which are unable to present the immunodominant epitope, CSP-ba

219 ochondria are uncoupled, SDH-deficient cells are unable to preserve their viability, suggesting that

220 ry approval to treat multiple sclerosis (MS) are unable to prevent inflammatory tissue damage in the

221 this subpopulation, memory B-cell depletion was unable to prevent relapse, which was probably caused

222 Interestingly, isolated DCs alone, however, are unable to produce CCL22, but instead require T cell

223 hermoelectric figure-of-merit materials have been unable to produce the voltage and power levels requ

224 atterns, but that global inhibitory networks were unable to produce input-output transformations that

225 While many response biomarkers will be unable to progress from their status as markers of bi

226 ved macrophages or skin fibroblasts in vitro were unable to proliferate, and overexpression of Mfrn1-

227 R-48 variant that disrupts binding to USP-46 was unable to promote USP-46 abundance in vivo Finally,

228 I of the inner core lipopolysaccharide (LPS) were unable to propagate phage LL5, as were mutants defi

229 However, these studies are unable to prove biologic plausibility and causality

230 wards N(2) O was suppressed in solvents that are unable to provide hydrogen bonding to the second-sph

231 zes, current match algorithm implementations are unable to provide match results in real time.

232 are, even the most sophisticated approaches are unable to provide meaningful answers when the user l

233 They are unable to provide the high demand of multiplexing, h

234 r species or local communities and have thus been unable to provide a general evaluation of the overa

235 dentify the time of onset of OMG or GMG, (3) were unable to provide information about previous treatm

236 ve the advantage of large-sample sizes, they are unable to quantify the cellular basis of structural

237 n of saffron authenticity, but used alone it is unable to quantify purity.

238 with familial hypercholesterolemia (FH) who are unable to reach low-density lipoprotein cholesterol

239 18, a membrane-impermeable CA inhibitor that is unable to reach the brain tissue, had no effect.

240 6%) of women were married, 254/2,107 (12.3%) were unable to read and write, and 1,505/2,247 (67.0%) w

241 Moreover, MGL(short) H259T was unable to recognize cancer-associated Tn epitopes on

242 nowledge, other indexing methods have so far been unable to record abundances efficiently across larg

243 nt cell lines; however, sensitive cell lines were unable to recover and replicate DNA even when the i

244 However, current bioprinters are unable to reliably print the fundamental unit of all

245 In turn, these models may be unable to reliably detect biological effects.

246 n under extreme conditions, SARS-CoV-2 virus is unable to replicate in these mosquitoes and therefore

247 he presence of cells with cytotoxic capacity was unable to replicate the efficacy of radiation with c

248 Therefore, we were unable to replicate the "qM" component and its corr

249 sychological states in other individuals but are unable to represent others' beliefs.

250 d easily accessible, the culture environment is unable to represent in vivo extracellular matrix (ECM

251 However, approaches to date have been unable to reproduce key features of spherical HDLs,

252 Recent studies have been unable to reproduce the original experiments in the

253 Despite extensive efforts, we were unable to reproduce the finding that glutamate, AP5

254 ssembly-deficient variants of these proteins are unable to rescue microcompartment formation, highlig

255 This mutant was unable to rescue the DeltaponB-ponA (ts) strain, whi

256 the-art long-term global climate simulations are unable to resolve the spatiotemporal characteristics

257 rdinate (i.e., the glycosidic torsion angle) is unable to resolve the intermediates.

258 Thus, oocytes are unable to respond immediately to DNA damage, but ins

259 Our results show that VAD calves are unable to respond to the mucosal BRSV-NP vaccine, ar

260 s lacked surface expression of IL-2Rbeta and were unable to respond to IL-2 stimulation.

261 with simultaneous deletion of Msi1 and Msi2 were unable to respond to light and displayed severely d

262 roteins altered for phosphotransfer activity were unable to restore atxA transcription to parent leve

263 41% of patients who were working previously were unable to return to work.

264 ically bulk nature of these techniques, they are unable to reveal the subpopulation variation in EET

265 Here we report that LiNO(3), which is unable to ring-open DOL, possesses a previously unkno

266 to error correct Rmap data, named cOMet, it is unable to scale to even moderately large sized genome

267 When pheromone-stimulated cells are unable to sense a gradient, they form mating project

268 us studies of insulo-opercular seizures have been unable to separate insular and opercular onset.

269 We were unable to separate the pb-like and zen2-like specif

270 action or expansion of specific regions, and is unable to show additional dimensions of the dataset.

271 sma increase of APOB-containing lipoproteins is unable to stimulate m-RCT.

272 Peptides that were unable to stimulate PAR4-dependent calcium signalin

273 The mutant TRIFs were unable to support STING signaling, although they we

274 roup of patients, the uncommitted precursors were unable to support the constant development of B cel

275 that liver-specific deletion of Acly in mice is unable to suppress fructose-induced lipogenesis.

276 xhibited compromised virulence functions and were unable to suppress NPR1 accumulation, FLS2 accumula

277 eractions with the SYNV nucleocapsid protein were unable to suppress transcription.

278 n deleted for the c-di-AMP cyclase gene dacA is unable to survive in rich medium unless it acquires c

279 T cells in B cell-deficient mice, these mice were unable to survive the infection.

280 PrimPol, targeting a catalytic metal ligand, was unable to synthesize primers, likely due to protein

281 sis of SLs-and we determined that the mutant was unable to synthesize SLs.

282 istorically underrepresented (HU) groups may be unable to take advantage of traditional summer resear

283 proaches for nanomaterial delivery in plants are unable to target specific subcellular compartments w

284 quire further lowering of LDL cholesterol or be unable to tolerate statins.

285 MHV strain is restricted to the optic nerve, is unable to translocate to the retina, and causes only

286 Captured p65 was unable to translocate to the nucleus or transactivat

287 In contrast, CD36(High) LSCs were unable to transplant leukemia but were highly proli

288 aMs that colocalize with the channel complex are unable to trigger Ca(2+)-dependent feedback of chann

289 reticulum (ER) stress sensing; however, they were unable to trigger UPR-related transcriptional respo

290 ate information intrinsic to the data or iv) are unable to uncover multiple associations between diff

291 cking GSK3alpha display altered motility and are unable to undergo hyperactivation, which is essentia

292 ven the small number of patients, this study was unable to unequivocally confirm the existence of a b

293 However, overexpression of IKZF3 was unable to upregulate IL-10 at the mRNA or protein le

294 Cortical neurons are unable to use idebenone as a direct mitochondrial el

295 terminal deoxynucleotidyl transferase (TdT) is unable to use RNA as a substrate altogether.

296 Results show that CFS skeletal muscle cells are unable to utilise glucose to the same extent as heal

297 The oligotroph was unable to utilize the proteinaceous substrate by its

298 tained under real-world clinical conditions, was unable to validate the kSORT assay for detection of

299 We were unable to validate previously reported findings of

300 d degree or higher uterine prolapse, if they were unable to walk or stand without help, or if they ha