ライフサイエンスコーパス: be unclear

1 nset and response to antipsychotic treatment is unclear.

2 these potentially antagonistic requirements is unclear.

3 site or a consequence of hypertrophic growth is unclear.

4 precise role of the bza operon protein CobT is unclear.

5 ing, antibodies to the new species in humans is unclear.

6 n the context of the chromatin organization, is unclear.

7 ut how this architecture influences activity is unclear.

8 he gut, the source of this electron acceptor is unclear.

9 le in disinfection byproduct (DBP) formation is unclear.

10 the relative importance of these mechanisms is unclear.

11 longevity in the presence of multimorbidity is unclear.

12 o the SNARE assembly, the structure of VAMP2 is unclear.

13 adation events regulate BCR functions in GCs is unclear.

14 humans, but the underlying mechanistic basis is unclear.

15 ts/caveolae) are involved in these processes is unclear.

16 nking to the existing peptidoglycan meshwork is unclear.

17 , the mechanism by which m-Tyr damages cells is unclear.

18 e mutations can eradicate premalignant cells is unclear.

19 diated endothelial damage, but the mechanism is unclear.

20 ilar effects on the neural circuitry of fear is unclear.

21 ism through which tinnitus affects attention is unclear.

22 ut the origin of this phenotypic variability is unclear.

23 the pathological basis for this association is unclear.

24 arn about vocal cues for parenting responses is unclear.

25 transitioning brain states under anesthesia is unclear.

26 How this balance in maturation is maintained is unclear.

27 reasing the numbers of CTCs in breast cancer is unclear.

28 the mechanism underlying these observations is unclear.

29 ortance of this context in different species is unclear.

30 ces in physical activity and feeding pattern is unclear.

31 the translocation of transfer RNA (mt-tRNA) is unclear.

32 How cells form MDCs is unclear.

33 The mechanism for similar graft survival is unclear.

34 aling, but its interactive role with osterix is unclear.

35 eration (AMD), the role of retinal perfusion is unclear.

36 s causally related to diabetes complications is unclear.

37 es, but their relationship to brain circuits is unclear.

38 g keratohyalin granules (KGs) whose function is unclear.

39 adult cardiomyocytes involved in this repair is unclear.

40 efined by individual or subgroups of markers is unclear.

41 equilibrates to warming on longer timescales is unclear.

42 PAMPs and DAMPs extends to metabolic shifts is unclear.

43 trate specificity leading to drug resistance is unclear.

44 type 2 diabetes (T2D) in poststroke recovery is unclear.

45 wo signaling systems interact during C and E is unclear.

46 ibing behavior impacts persistent opioid use is unclear.

47 nvolved in plant defense, their biosynthesis is unclear.

48 ; however, its role during early development is unclear.

49 e consequences of large joint osteoarthritis is unclear.

50 ectively activated in the context of meiosis is unclear.

51 stressors, but what maintains this diversity is unclear.

52 ol, but the mechanistic basis of disassembly is unclear.

53 processes in the development of hypertension is unclear.

54 nfluence on peri-implant soft tissue healing is unclear.

55 to alterations in uteroplacental physiology is unclear.

56 pared with land-based transportation systems is unclear.

57 ukemia nuclear bodies (APBs), whose function is unclear.

58 xenobiotic and the impact on host responses is unclear.

59 preserved left ventricular systolic function is unclear.

60 t the mechanistic regulation of this process is unclear.

61 the relevance of this interaction in mammals is unclear.

62 n (eGFR) by the CKD-EPI formula versus both] is unclear.

63 f EZH2 from a gene repressor to an activator is unclear.

64 ut the underlying mechanism of this response is unclear.

65 lar, whether oncogenic signalling has a role-is unclear.

66 d growth in the remodeled tumor-promoting BM is unclear.

67 based on the frequency of airway suctioning is unclear.

68 cess stimuli depending on recent experiences is unclear.

69 However, the clinical course of the disease is unclear.

70 ivary microbiome composition and body weight is unclear.

71 tions on two alleles impact ATP7B properties is unclear.

72 owever, in IL-23-mediated joint inflammation is unclear.

73 arly erythropoiesis and hemoglobin switching is unclear.

74 erconnected across the brain and spinal cord is unclear.

75 ism of, and connection between, these events is unclear.

76 t organizes to function throughout the colon is unclear.

77 from specific risk factors for liver disease is unclear.

78 -induced symptoms and inflammation over time is unclear.

79 How the two processes are coordinated is unclear.

80 The underlying pathomechanism is unclear.

81 e BG output nuclei and in downstream targets is unclear.

82 How these events are coordinated is unclear.

83 r other factors support this dynamic process is unclear.

84 locally contaminated, although the mechanism is unclear.

85 g neuronal circuit in its native environment is unclear.

86 portance of mRNA localization to centrosomes is unclear.

87 g to mast cell degranulation and anaphylaxis is unclear.

88 , the time required to attain maximal effect is unclear.

89 plays a role in GnRH-1 neuronal development is unclear.

90 will adapt to evade neutralizing antibodies is unclear.

91 tes are selectively targeted for degradation is unclear.

92 ter percutaneous coronary intervention (PCI) is unclear.

93 antigen (PSMA) PET/CT, a newer examination, is unclear.

94 ut the mechanism of CPT's beneficial effects is unclear.

95 ether these are parallel or dependent events is unclear.

96 lly transmitted to the gene expression level is unclear.

97 er, LOAD genetic architecture and prediction are unclear.

98 nesis, mechanisms underlying such phenotypes are unclear.

99 tion between progenitor and stem cell states are unclear.

100 rbated inflammation during DENV pathogenesis are unclear.

101 ; however, its frequency and clinical impact are unclear.

102 terms of risk of subsequent high-grade ACLF are unclear.

103 stration of azithromycin for a longer period are unclear.

104 e underlying mechanisms driving this process are unclear.

105 me group of participants, and several issues are unclear.

106 ble sanctuary specifically in this reservoir are unclear.

107 vascular remodeling contributes to recovery are unclear.

108 etic factors that determine their dimensions are unclear.

109 ts of GAs on agonist-mediated TRPA1 activity are unclear.

110 mechanisms responsible for these phenotypes are unclear.

111 oarthritis, but the benefits of this therapy are unclear.

112 ng neural underpinnings of such a phenomenon are unclear.

113 ctivation of SARM1 is stringently controlled are unclear.

114 tory mechanisms underpinning this phenomenon are unclear.

115 ease 2019 (COVID-19) in people with diabetes are unclear.

116 However, the causes of CA in human cancer are unclear.

117 The causes are unclear.

118 nisms by which mucus affords this protection are unclear.

119 he pathogenesis of human gastric cancer (GC) are unclear.

120 become limiting under lysosomal dysfunction are unclear.

121 l circuit mechanisms underlying this ability are unclear.

122 remote impacts on the Arctic climate system are unclear.

123 A virus, but the reasons for this difference are unclear.

124 uch risks are due to shared familial factors are unclear.

125 ctions and reducing LPS-induced inflammation are unclear.

126 misfolded protein expression in cancer cells are unclear.

127 asymmetry and biased centrosome segregation are unclear.

128 bly other herpesviruses) and HIV persistence are unclear.

129 y system; however, the underlying mechanisms are unclear.

130 CNS); however, their coordinating mechanisms are unclear.

131 g functions of these glucose-sensing neurons are unclear.

132 germline and the underlying pathophysiology are unclear.

133 RP-1 and the molecular mechanism(s) involved are unclear.

134 hese disparate functions of Sema3A signaling are unclear.

135 back inhibition and its role in pathogenesis are unclear.

136 ses, the underlying psychological mechanisms are unclear.

137 duction and recruitment to the injured heart are unclear.

138 tobacco dependence but underlying mechanisms are unclear.

139 ns inducing ocular and neuronal pathogenesis are unclear.

140 the neural elements mediating symptom relief are unclear.

141 esynchronization and its global organization are unclear.

142 ticity but the molecular mechanisms involved are unclear.

143 n receptor, TRPV1, outside of sensory nerves are unclear.

144 ons in animals and humans, its structure has been unclear.

145 erminus and how they cause human disease has been unclear.

146 tized in periurban and rural communities has been unclear.

147 the specific role played by each ligand has been unclear.

148 e or negative regulators of the synthase has been unclear.

149 erations, but its impact on liver cancer had been unclear.

150 ented that their roles in programme delivery were unclear.

151 erlying the beneficial effect of Mt transfer are unclear and likely multifactorial.

152 partial activity can complement one another, is unclear and could affect the severity of BRCA1-associ

153 d mechanism of antidepressant action of BoNT is unclear and maybe hypothetically attributed to the di

154 who undergo concurrent resection of CLM/EHD is unclear and the impact of somatic mutations has not b

155 ection against a primary Chlamydia infection is unclear and was a focus of this work.

156 he chronic joint disease osteoarthritis (OA) is unclear, and this lack of clarity is detrimental to e

157 the effects of exercise on tumor progression are unclear, as are the cellular actors involved.

158 could be targeted with maternal intervention are unclear, as few chronic gestational inflammation mod

159 ATP in regulating Pro-sigma(K) cleavage has been unclear, as has the impact of the channels on MC an

160 cell chloride/bicarbonate exchanger pendrin is unclear, as are potassium's role in this response and

161 ory behavior is performed by human Tfh cells is unclear, as technology to track them in situ has been

162 The cause of the improved survival was unclear, as complete blood counts, splenic and marro

163 d the cardiovascular system but in ways that are unclear because of technical limitations (anesthesia

164 impact subsequent human cortical development is unclear because experimental spatial control of corti

165 However, the nature of these abnormalities is unclear because most focus on responses to stimuli fr

166 ipid storage in LDs with cellular metabolism are unclear but relevant to obesity-related diseases.

167 The mechanism underlying this is unclear but may be due to N-methyl-D-aspartate recept

168 The underlying causes are unclear, but epidermal, unmyelinated axons have been

169 s and possible off-target effects in cellulo are unclear, delaying the translation from preclinical s

170 w nasal cannula during and before intubation is unclear despite a number of randomized clinical trial

171 espond to such treatment or if the diagnosis is unclear, endoscopy, esophageal manometry, and esophag

172 How MutLgamma acts to generate expansions is unclear given its normal role in protecting against m

173 Until now, it has been unclear how the origin DNA is guided by ORC-Cdc6 an

174 However, it is unclear how Atg11 concentrates Atg32 to generate mito

175 d prognostic marker for patients with PC, it is unclear how CA19-9 monitoring should be used to guide

176 At present it is unclear how common reinfection with SARS-CoV-2 is and

177 However, it is unclear how de novo telomere addition (dnTA) is regul

178 However, it is unclear how distinct structural features of the two P

179 However, it is unclear how ecotypes arise and how their distinctive

180 However, in many cases, it is unclear how escaping host spatial control benefits gu

181 h the heterotrimeric G(s) protein(2), but it is unclear how GPR52 and G(s) couple for signal transduc

182 ibutes to advanced age-related disorders, it is unclear how Kruppel-like factor 5 (Klf5), an essentia

183 However, it is unclear how MAP2 is associated with synaptic plastici

184 However, it is unclear how memory-eligible neurons react during lear

185 sorder Parkinson's disease (PD); however, it is unclear how mitochondrial impairment and alpha-synucl

186 It is unclear how satisfaction with RYGB surgery changes ov

187 rtant roles during early development, but it is unclear how Stat3 is activated.

188 Nonetheless, it is unclear how such biological changes are linked to rel

189 lly regulate the N-terminal p63 isoforms, it is unclear how the C-terminal p63 isoforms are regulated

190 It is unclear how the pleiotropic outcomes of evolution are

191 s responsible for object recognition, but it is unclear how the representation of visual objects is o

192 However, it is unclear how the repressive histone modification H4K20

193 of protumor and antitumor functions, yet it is unclear how the TME regulates this macrophage heterog

194 However, it is unclear how these longitudinal patterns differ from t

195 and animals has been extensively tracked, it is unclear how these nascent economies developed within

196 ies is important for protection, however, it is unclear how these protective antibodies function.

197 In addition, it is unclear how these signals convey specificity to the s

198 stimation errors accumulate over time and it is unclear how they are corrected.

199 rogenesis declines dramatically with age, it is unclear how they might contribute to behavior later i

200 As a result, it is unclear how they perform this important reaction.

201 their future language abilities; however, it is unclear how variation in this input relates to prever

202 e speech integration occurs in the brain, it is unclear how visual and auditory cues are combined to

203 It is unclear, however, whether host species possess innate

204 However, it is unclear if alpha5-GABA(A)Rs are altered in vivo or re

205 oposed lineage heterogeneity within GMPs, it is unclear if committed progenitors already exist among

206 It is unclear if endogenous activity influences circuit and

207 However, it is unclear if exceptional polymer length of vHMM-HA is i

208 e often diagnosed after advanced disease, it is unclear if laminin-111 protein therapy at an advanced

209 However, it is unclear if modifying the expression of select genes t

210 To date, it is unclear if other prenatal steroids also contribute to

211 uration and Alzheimer's disease (AD), but it is unclear if sleep duration is a manifestation of the A

212 the level of families and hospitals, but it is unclear if spillover is relevant at larger scales.

213 It is unclear if that silence requires minimum H3K27me3 lev

214 It is unclear if the (99m)Tc-sodium phytate ((99m)Tc-SP) is

215 It is unclear if the flu vaccine exacerbates immune events

216 It is unclear if the risk truly increases during pregnancy.

217 nd antimicrobial subscription models, but it is unclear if these will be included in final legislatio

218 It was unclear if, besides the direct transforming effect v

219 ring subsequent antiretroviral therapy still is unclear.IMPORTANCE The antiretroviral drug rilpivirin

220 gnosed hereditary hemochromatosis, but risks are unclear in mostly undiagnosed p.C282Y homozygotes id

221 The mechanistic principles, however, are unclear, mainly because structures of higher-order a

222 Current evidence is unclear regarding the usefulness of screening for pin

223 are poorly understood and, consequently, it is unclear the extent to which TCRs targeting the same A

224 However, it is unclear to what extent metabolic health changes over

225 It is unclear to what extent sensory processing areas are i

226 as not been empirically demonstrated, and it is unclear to what extent stalling may limit the power o

227 It is unclear to what extent the population is homogeneous

228 y, American football and boxing, although it is unclear to what extent this is clinically relevant.

229 However, it is unclear upon tissue loss, such as complete loss of ce

230 from cyanobacterial to chlorophyte dominance are unclear, we experimentally tested phytoplankton resp

231 ls reside in tissues such as the gut, but it is unclear what mechanisms maintain HIV latency in the b

232 s are altered in the context of diabetes, it is unclear what regulates localization of insulin granul

233 However, it is unclear what role these factors play in compacting th

234 ipation in post-stroke survivors, however it is unclear what the most effective types of exercise int

235 It is unclear what the optimal testing policy is in men who

236 It is unclear where endogenous podocyte APOL1 resides, beca

237 and shock within the same experiment, it has been unclear whether the observed activity reflects how

238 tream processing faces or bodies, but is has been unclear whether the same is true for other visual c

239 At present, it is unclear whether and how TDP-43 and tau are associated

240 y shown to be recruited by VWM paradigms, it is unclear whether any portion of cerebellum actively en

241 However, it is unclear whether cell polarity is established through

242 tary patterns tend to be of poor quality, it is unclear whether dietary patterns established in adole

243 It is unclear whether differences in estimations are due to

244 It is unclear whether early postoperative complications pre

245 ylation are hallmarks of 2i exposure, but it is unclear whether epigenetic alterations are required t

246 lectivity in visual cortex of carnivores, it is unclear whether experience exerts a permissive or ins

247 phate ion (Pi) uptake remain unknown, and it is unclear whether foliar P applications can meet plant

248 ding receptors and various effectors, but it is unclear whether in addition to the scaffolding role b

249 ically identical population of cells, but it is unclear whether it has a role in the development of m

250 stability, splicing, and translation, but it is unclear whether it is also has a physiological role i

251 lation manifests during disease; however, it is unclear whether lipid homeostasis is adversely affect

252 geal surgery negatively affect HRQOL, but it is unclear whether medical and surgical complications di

253 Moreover, it is unclear whether or not recognition and quality contro

254 It is unclear whether P6 MA activates neurons in the brain

255 Thus, it is unclear whether permeability to individually injected

256 evidence has all been indirect [4-7], and it is unclear whether plastic debris is the source of these

257 It is unclear whether PRDM16 plays a similar role in neurog

258 r cell lines (CCLs) exist for many drugs, it is unclear whether preclinical samples can be used to pr

259 However, it is unclear whether RFSs also utilize MiDAS and to what e

260 It is unclear whether severe acute respiratory syndrome cor

261 However, it is unclear whether spatially patterned Rho1 activity alo

262 However, it is unclear whether staffing levels are more likely to be

263 However, it is unclear whether super-spreading events occurred durin

264 It is unclear whether the ACA is also associated with incre

265 However, it is unclear whether the amyloids of lung origin (1) are n

266 o too does health and wellbeing; however, it is unclear whether the associations are causal.

267 In glioma WHO grade II, it is unclear whether the extent of MGMT promotor methylati

268 It is unclear whether the increase among men is being drive

269 ame- or opposite-sex conspecifics(1), but it is unclear whether the intent and neural encoding of the

270 It is unclear whether the number of steps per day and the i

271 vent of this and other therapies for SMA, it is unclear whether the paralysis associated with the dis

272 However, it is unclear whether the transfer of auditory information

273 disease (CHD) and depression is evident, it is unclear whether the two diseases have shared underlyi

274 However, it is unclear whether there is abnormal reward-linked effec

275 However, it is unclear whether these changes would be accompanied by

276 It is unclear whether these differing types of arrhythmia r

277 It is unclear whether these features respond to anti-VEGF t

278 nto tight orbits around white dwarfs, but it is unclear whether these planets can survive the journey

279 gh prevalence of respiratory viruses, but it is unclear whether these viruses were causing infection

280 t of high-throughput omic techniques, and it is unclear whether they represent the best possible targ

281 However, it is unclear whether this applies to social contexts, and

282 However it is unclear whether this finding can be replicated in a l

283 However, it is unclear whether this is due to differences in early p

284 multiple sclerosis clinical outcomes but it is unclear whether this is mediated by an excess of extr

285 ) and community-acquired pneumonia (CAP), it is unclear whether this remains the case in the setting

286 However, it is unclear whether this specific function is related to

287 rstanding spatial pollutant patterns, yet it is unclear whether uncertainties associated with tempora

288 But it is unclear whether virus per se induces bronchial mucosa

289 It is unclear whether visual function is affected by myopic

290 vertebrates and other neglected taxa, and it is unclear whether well-studied taxa, such as vertebrate

291 oing extracorporeal membrane oxygenation, it is unclear which cannulation method carries a higher ris

292 Particularly, it is unclear which defects are responsible for the emergen

293 In many cases, it is unclear which experimental features or model assumpti

294 However, it is unclear which motifs are prone to impact transcriptio

295 Currently, it is unclear which residues in the UGT2B7 cofactor binding

296 sleep-related memory processes [1-3], but it is unclear which specific sleep features are dependent u

297 However, it is unclear which subpopulations of B cells express GZMB

298 APE2 in DNA repair is poorly understood, it is unclear why BRCA-deficient cells require APE2 for via

299 It is unclear why some individuals develop AN while most do

300 It is unclear why some tissues are refractory to the mitoge