1 field method, but its efficiency has yet to
be validated.
2 ional roles of most of these genes remain to
be validated.
3 ative genes; results for only 11 genes could
be validated.
4 resentative of the interlayer cluster center
is validated.
5 at the measurements of various CC parameters
are validated.
6 ve novel antagonist (S)-18g (K(i) = 3.66 nM)
was validated.
7 atlas of mtDNA content in mammalian tissues
was validated.
8 tifying patients at risk, but only some have
been validated.
9 regulators and hormone signaling components
were validated.
10 testing period, the previous cut-off points
were validated.
11 rimary outcome, by intention to treat (ITT),
was validated abstinence from smoking at the 6-month fol
12 After the optimization, the method has
been validated according to EU regulation and finally ap
13 The optimized method
was validated according to authorities' guidelines and r
14 The method
was validated according to international guidelines and
15 The method
was validated according to the European Medicines Agency
16 The optimized MD-AF4 based method has
been validated across different instrument platforms, th
17 For robustness, models
were validated across imaging sites.
18 The results
were validated addressing the N-status distribution and
19 on smaller spatial scales, and these need to
be validated against fisheries data.
20 The new simulator
is validated against several benchmark problems (involvi
21 The 3D patient scan
was validated against actual measurements to ensure accu
22 The predictive potential of this model
was validated against experimentally calculated growth r
23 P0.1vent
was validated against measures of drive (electrical acti
24 The model
was validated against surgical data.
25 The method
was validated against the gold standard Limulus Amoebocy
26 The automated choroid segmentations
were validated against manual segmentations, and MCT mea
27 ) were tested on institutional data; only 16
were validated against publicly available data.
28 tions; however, only a handful of these have
been validated and confidently linked to their target ge
29 The method
was validated and demonstrated excellent detection and q
30 The modified method
was validated and met the performance criteria required
31 3 m], and > 1,663 ug/L [< 30 mL/min/1.73 m])
were validated and compared with the conventional D-dime
32 Whole exome sequencing findings
were validated,
and reported mutations were compared by
33 expression of COL2A1 and ACAN, both of which
are validated as direct targets of miR-3085-3p.
34 cogene Epithelial Cell Transforming 2 (ECT2)
was validated as a direct key target.
35 This peptide fraction
was validated as a natural preservative and substitute f
36 lymerase chain reaction assay for M. leprae,
were validated as clinical diagnostic assays according t
37 nes (serpina3n, lcn2, ackr1, lrg1 and lamc3)
was validated at the level of inner BRB cells.
38 The findings
were validated at a 3-year follow-up (N = 59) of the sam
39 human vertebra simulation designs that have
been validated based on the in vivo ultrastructure and p
40 ovide an exothermic pathway to taxadiene and
are validated by comparison to closely related structure
41 fied motifs, but also reveal new motifs that
are validated by in vitro binding assays.
42 The predictions by these empirical equations
are validated by several MOFs with an average deviation
43 These changes
are validated by targeted and global experimental analys
44 on (MIC) values generated from our technique
are validated by the gold standard broth microdilution (
45 The predicted hinges
are validated by using permutation tests on B-factors.
46 Both methods have
been validated by measuring pK(a) values of compounds, f
47 The analytical method has
been validated by verifying the different performance cr
48 The specificity of our biosensor
is validated by comparing the response to target bacteri
49 Accuracy of the proposed model
is validated by comparison studies with available experi
50 Our model
is validated by experimental data and allows predicting
51 s well as numerical simulations; the concept
is validated by means of a set of experimental tests on
52 l of the membrane-bound Dfg5*GPI-CWP complex
is validated by molecular dynamics (MD) simulations and
53 The approach
is validated by synthesis of a NP that sequesters and in
54 Our interpretation
is validated by the absolute calibration of the acoustic
55 The mediated electrochemical approach
is validated by the radiometric measurements of simulate
56 The finite element analysis
is validated by uniaxial compression to buckling of 3D p
57 acids (eGFP15eGFP) with this protocol, which
is validated by using an eGFP monomer as a reference.
58 The method
is validated by using both negative-staining (NS) and cr
59 pendent and the other Na(+)-dependent, which
was validated by biochemical analyses.
60 RISK6 utility
was validated by blind prediction using quantitative rea
61 th core NHEJ proteins, including Ku70, which
was validated by co-immunoprecipitation.
62 elial cell sorting in wild type C57BL/6 mice
was validated by comparative transcriptome analysis with
63 The model
was validated by comparing modeled CPV(24h) values to me
64 his new automated system for strain analysis
was validated by comparing the outcome of these analysis
65 Smoking status
was validated by cotinine assay.
66 model reactions, and the diagnostic concept
was validated by determining the interindividual variati
67 s, and the impact of the identified variants
was validated by functional assays using the patients' P
68 Protein expression of selected genes
was validated by immunofluorescence on retinal wholemoun
69 luding new nutrients supporting growth; (ii)
was validated by in vivo growth screens that included pr
70 This conclusion
was validated by long-term time-lapse live-imaging exper
71 erimentally determined partition coefficient
was validated by molecular dynamics (MD) simulations wit
72 functional importance of the identified site
was validated by mutagenesis and biochemical modificatio
73 The therapeutic approach
was validated by oral administration of 27 in orthotopic
74 ity of the viral polymerase (L) protein that
was validated by photoaffinity labelling-based target ma
75 every case, the described experimental setup
was validated by retrieving the original literature cond
76 able for controlling BODIPY localization and
was validated by sensitization of mammalian cells and ne
77 The method
was validated by spike-recovery experiments with equilib
78 l of the arrestin-1-enolase-1 complex, which
was validated by targeted substitutions of charge-pair i
79 veness for on-site and portable measurements
was validated by testing solid wastewater samples random
80 The present procedure
was validated by the analysis of standard reference mate
81 This approach
was validated by the high agreement between native MS an
82 Our screening approach
was validated by the identification of known adhesion-re
83 ndicating the thickening of cell wall, which
was validated by the transmission electron microscopy.
84 The assay accuracy
was validated by titration of 10-80% mixture of acetylat
85 The reliability of the ZnCl(3)(-) detection
was validated by total zinc determination using laser ab
86 The resistance function of Pm24
was validated by transgenic assay, independent mutants,
87 The function of Pm5e
was validated by transgenic assay, loss-of-function muta
88 The predictive effectivity of the model
was validated by using 67 cancers from WCH and 47 cancer
89 of Q92R-Sec61alpha1 on neutrophil maturation
was validated by using HL-60 cells, in which transductio
90 This model
was validated by using synthetic covalent MSA-2 dimers,
91 tative new HPV sequences, including one that
was validated by wet-lab experiments.
92 ing potential novel therapeutic avenues that
were validated by a high hit rate in a targeted small mo
93 These hub molecules
were validated by an independent dataset.
94 The 3D printed MALDI targets
were validated by analysis of different types of bacteri
95 The models
were validated by analyzing experimental data demonstrat
96 Chronic health conditions (CHCs)
were validated by clinical assessment.
97 e formation of heteromeric protein complexes
were validated by coimmunoprecipitation and Western blot
98 oth the homochiral and heterochiral products
were validated by density functional theory calculations
99 o Mamu-A1*001-positive animals; two of these
were validated by ex vivo tetramer staining.
100 elf-regenerative cycle of iminodiacetic acid
were validated by experiment.
101 Simulations
were validated by experimental measurements.
102 Imaging results
were validated by H&E histology, which showed evidence o
103 These results
were validated by high performance liquid chromatography
104 Classifier genes
were validated by Immunohistochemistry (IHC) using tissu
105 Candidate genes
were validated by independent gene mutation.
106 he estimated proportions of these cell types
were validated by independent measures of tumor purity,
107 The resulting markers
were validated by linking them with clinical outcomes (v
108 The results
were validated by liquid chromatography-mass spectrometr
109 ved with the carbon dot-facilitated delivery
were validated by measuring significant reductions in th
110 The in-vivo metabolic data
were validated by mitochondrial respirometry, enzyme act
111 The functional state assignments
were validated by molecular dynamics simulations, and th
112 The reproducibility and safety of the method
were validated by MRI and histology.
113 Relevant miRNAs
were validated by qRT-PCR and in situ hybridization (ISH
114 of hospitals, data completeness and accuracy
were validated by reabstraction of the data.
115 These observations
were validated by rescuing the phenotype with myo-inosit
116 ronic (LTB, CXCL6, ITGAX) renal lesions that
were validated by RT-PCR and IHC.
117 ecay kinetics in the presence of antibiotics
were validated by the colony counting method, field emis
118 ructural models, docking and scoring schemes
were validated by their ability to rank known sweet-tast
119 The genes identified
were validated by their re-expression after treatment wi
120 Single-site Au/C catalysts have previously
been validated commercially to produce vinyl chloride, a
121 Critically, eMSOT imaging findings
were validated directly by histopathologic assessment of
122 The in silico analysis
was validated ex vivo, through T cell proliferation expe
123 The importance of these in-silico findings
is validated experimentally by site-directed mutagenesis
124 The computational results
were validated experimentally (up to 92:8 er), providing
125 redicted phenotypes for a selection of these
were validated experimentally with results being consist
126 The method
was validated following the European Commission Decision
127 In order for AUC to
be validated for a GMP environment, stringent requiremen
128 biomarkers have been reported, but none has
been validated for approval by the Food and Drug Adminis
129 Background Chest radiography has not
been validated for its prognostic utility in evaluating
130 5b-is applied in this manner but has not yet
been validated for this patient group.
131 tibody modified GNR based lateral flow assay
is validated for the determination of C-reactive Protein
132 The method
was validated for accuracy using CRMs DOLT-5 and DORM-4.
133 The method
was validated for analysis of selected ethyl esters pres
134 ive LFCs in millimeter gap CC rheo-MRI cells
was validated for Newtonian and simple yield stress flui
135 The interaction pattern
was validated for one gene pair (GRMZM2G035341 and GRMZM
136 The final method
was validated for some representative phospholipids, sho
137 The method
was validated for specificity, sensitivity (0.001% w/w)
138 The methodology
was validated for tea, apple-based beverage and pineappl
139 A HPLC-UV/FLD method
was validated for the quantification of six polyethylene
140 Dynamic body acceleration has now
been validated frequently, both in the laboratory and in
141 More than half of these
were validated from PlaMoM, a database for plant mobile
142 The analytical methods
were validated fully in accordance with the SANTE/11945/
143 The method
was validated,
giving correlation factors over 0.98 and
144 If these findings
are validated,
IFNL4 genotype could be added to the dono
145 ng to predictions of relative virulence that
are validated in a mouse infection model.
146 If these findings
are validated in other VCA patients, vascular injury in
147 The altered proteins
are validated in two independent cohorts, showing partia
148 es a framework for a polygenic risk score to
be validated in future studies.
149 ndations, these recommendations will need to
be validated in prospective clinical trials.
150 Now that this latent phenotyping model has
been validated in a general population sample, it can be
151 consensus, and their performance has not yet
been validated in a well-defined cohort of patients with
152 FMRP-deficient related impairments have also
been validated in additional FXS patient-derived human-i
153 The concept of dormancy has
been validated in C. neoformans from both epidemiologica
154 Predicted synergies are provided and have
been validated in glioblastoma, breast cancer, melanoma
155 This mechanism has
been validated in human liver specimens from patients wi
156 Longitudinal bleeding risk scores have
been validated in patients treated with dual antiplatele
157 ary artery disease, however, its use has not
been validated in patients with severe aortic stenosis.
158 ent of thyroid nodules in adults but has not
been validated in pediatric patients.
159 This approach has not
been validated in PLWH.
160 Although this therapeutic approach has
been validated in randomised, phase 3 trials, evaluation
161 However, this paradigm has not
been validated in the English language.
162 This finding
is validated in both the accompanying MetaCardis cardiov
163 The test-negative design
is validated in outpatient, but not inpatient, studies o
164 After the recovery evaluation, the method
is validated in terms of linearity (coefficient of deter
165 This effect
was validated in 3 smaller cohorts, and was much stronge
166 This GPS(CAD)
was validated in 7,244 South Asian UK Biobank participan
167 The utility of 6qcNIR
was validated in a busy real-world clinical setting, and
168 (100% overall survival at 69 months), which
was validated in a large independent cohort.
169 The severity score
was validated in a second half of 2356 patients.
170 The final CXR-LC model
was validated in additional PLCO smokers (n = 5615, 12-y
171 The performance of classifier
was validated in an additional cohort of mCRPC patients
172 The final diagnostic panel of 28 features
was validated in an independent cohort (26 cases, 26 con
173 This signature
was validated in an independent cohort of 119 patients.
174 PIUKALL correlated with risk of relapse and
was validated in an independent cohort.
175 The final model
was validated in an independent external cohort (SHaRe [
176 ion rule for community-onset 3GC-R infection
was validated in an international cohort and could impro
177 r GAS growth and survival in human blood and
was validated in another M1T1 GAS strain, 5448.
178 The method
was validated in dedicated phantom and then applied to 1
179 ied four factors for a prognostic model that
was validated in internal and external cohorts.
180 The crucial role of hMATE1
was validated in lung adenocarcinoma cells (A549), which
181 anifesting as ventricular septation defects,
was validated in mice.
182 Critically, this
was validated in patient-derived explants where enzymati
183 eld potentials (LFPs) at implanted DBS leads
was validated in patients with neurological disorders.
184 Furthermore, the activity of CX-6258
was validated in several Ewing sarcoma and multiple myel
185 The overall quality of the candidate vaccine
was validated in silico and Molecular Dynamics Simulatio
186 The SPE-LC-MS/MS method
was validated in terms of limit of detection (1.29-29.17
187 g matrix-matched calibration, and the method
was validated in terms of relative retention time window
188 It
was validated in terms of specificity (methoxy/acetate s
189 The final model
was validated in the test cohort and the cohort of non-s
190 The image-based model
was validated in three external cohorts.
191 The approach
was validated in vivo in rats and non-human primates usi
192 determine in vivo selectivity, (18)F-OF-NB1
was validated in wild-type and sigma1R knock-out mice.
193 Longitudinal results
were validated in 2 external cohorts: (1) the NHANES III
194 These results
were validated in 2 independent patient cohorts (Glasgow
195 idate variants emerging from both strategies
were validated in a cohort of 283 patients with sickle c
196 refine this list and the top seven microRNAs
were validated in a larger panel of GBM cells using stat
197 Moreover, identified deleterious variants
were validated in a populational analysis (n = 96).
198 These findings
were validated in a second cohort of patients (n = 231).
199 nts at defined time points, and the findings
were validated in a second cohort of PTLDS and non-PTLDS
200 The differences in IL6 levels
were validated in a second independent Italian cohort; (
201 The findings
were validated in a separate external longitudinal cohor
202 These observations
were validated in an in vivo xenograft model, which show
203 These findings
were validated in an independent cohort of 310 epitopes
204 STS proteomic analysis results
were validated in an independent cohort of 41 adults wit
205 The anatomic findings
were validated in an independent cohort of acute stroke
206 on, regardless of therapy and these findings
were validated in an independent cohort of secondary pro
207 ial biomarkers and selected biomarker models
were validated in an independent patient group.
208 Seven derived models (28%)
were validated in at least 2 cohorts, reporting limited
209 ed with AD persistence at the age of 7 years
were validated in children with AD in an independent coh
210 f the parameters gamma and beta of the model
were validated in continuous wash experiments of chopped
211 Spinule subsets, dynamics, and recurrence
were validated in cortical neurons of acute brain slices
212 The 2 calculation models
were validated in European and North American cohorts (n
213 medication use - among which 38 associations
were validated in Nurses' Health Study II.
214 The findings
were validated in protein data and in RNA transcription
215 In total, 4 exonic, single-gene deletions
were validated in schizophrenia cases and none in contro
216 Eight compounds
were validated in secondary screening.
217 Candidate inhibitors
were validated in several viral infection assays.
218 Data
were validated in the ADEPT cohort.
219 Selected miRNAs
were validated in the plasma by qRT-PCR and at tissue le
220 blood pressure (P=0.58), these relationships
were validated in the UK Biobank (P<0.0001).
221 nd grain size using gene expression data and
were validated in three bi-parental populations.
222 Our findings
were validated in two autoimmune disease models by demon
223 e critically important molecular descriptors
were validated in two case studies to establish the impo
224 strains and their underlying signature SNVs
were validated in two subsequent analyses of 6,228 and 3
225 DR3 levels (in plasma and PBMCs)
were validated in unrelated cohorts (including long-term
226 and used to identify specific therapies that
were validated in vivo.
227 A subset of high-priority candidates
was validated,
including Myo16, Coro1A, MAP1B, ExoC1, GR
228 onavirus 2 infection risk, these data should
be validated independently, and randomized studies of BT
229 tamase, Bla(Mab), using a novel assay, which
is validated kinetically using the nitrocefin reporter a
230 The computational results
are validated on Rhodamine B (fluorescent drug l) and ot
231 The method
is validated on an estimation of the proportions of (i)
232 The method
is validated on biologically relevant proteins.
233 The method
is validated on eight biological phenomena, three synthe
234 rity score, derived from model coefficients,
was validated on a second, temporally discrete dataset o
235 The method
was validated on fish or swine processed food products c
236 Epidemiological parameters for COVID-19
were validated on a limited date range; where substantia
237 of the observed alternative pose remains to
be validated,
our structural results hint at the presenc
238 The algorithm
was validated qualitatively and quantitatively using the
239 p to the established Warburg impedance model
is validated theoretically and experimentally.
240 proach yields a record of RNA locations, and
is validated through identification of RNAs localized se
241 Simulated dose in representative models
is validated through in vitro spray measurements in 3D-p
242 much LS DNA as previously recognized, which
was validated through orthogonal analysis, and we propos
243 The method
was validated through recovery experiments at four conce
244 elded large sets of antibody candidates that
were validated through a panel of binding assays against
245 e B induced in vivo signals of the reporters
are validated to correlate well with the populations of
246 The method is fully automated, has
been validated to work well at two separate sites (an ac
247 All four compounds
were validated to cause hypocholesterolemia in Neuro-2a
248 The main results
are validated using a different p-tau217 immunoassay.
249 Findings could
be validated using the same valence localizers to predic
250 uizartinib and dexamethasone combination has
been validated using primary AML patient samples and xen
251 The method has
been validated using spiked samples (tap water, blood se
252 The classifier
was validated using a gene expression microarray dataset
253 Hyperspectral quantification of grain chalk
was validated using a segregating bi-parental mapping po
254 The atlas
was validated using an additional canine cohort with var
255 The non-HLA panel
was validated using an independent adult cardiac transpl
256 The method
was validated using finite element (FE) simulations and
257 Last, a subset of mutants
was validated using G protein activity biosensors in mam
258 kappaB activation following LD-STZ treatment
was validated using immunofluorescence and transgenic an
259 Among them, a sub set of primers (245 SSR)
was validated using polymerase chain reaction (PCR) ampl
260 Finally, the FO-SPR immunoassay
was validated using seven iTTP patient plasma samples, r
261 al of the cellulose- and antioxidant-rich OP
was validated using the 3,5-dinitrosalicylic acid and 2,
262 The methodology
was validated using the SRM NIST 1568a Rice Flour and re
263 The developed UCNP-LF test
was validated using whole blood reference panels contain
264 Several hits
were validated using a DNAJA1 inhibitor (116-9e) in cast
265 s (>0.10 AUC) and our interpretation methods
were validated using a similar model to identify known r
266 These results
were validated using a yeast trs23 temperature sensitive
267 The top 10 hits
were validated using an orthogonal assay for endogenous
268 Models
were validated using data from the TONIC (Treatment of N
269 Findings
were validated using external public datasets.
270 Findings
were validated using IDA in intact and digested bovine s
271 B-family polymerases
were validated using multiple siRNAs in a panel of NSCLC
272 ed a good separation of most fruit types and
were validated using quality control samples.
273 ession of the differentially regulated genes
were validated using quantitative real-time polymerase c
274 Differentially expressed miRNAs and mRNAs
were validated using RT-qPCR.
275 Candidate markers
were validated using samples from year-long observationa
276 Variants believed to cause IBD
were validated using Sanger sequencing.
277 quitous and essential in all eukaryotes, has
been validated via genetic and pharmacological methods a
278 Some of the predictions we generated
were validated via assessment of ectopically expressed w
279 The simulation results
are validated with experimental data in terms of Single
280 Predicted proteins encoded by the sequence
are validated with nucleotide-to-protein alignments usin
281 and wounds, with 13 out of 16 species tested
being validated with in vitro studies.
282 The method
is validated with a multiphysics model of the intestine
283 Tag authentication
is validated with a variety of orthogonal detection meth
284 The reconstruction
is validated with withheld proxies as well as independen
285 The resulting score
was validated with 33,616 individuals from two fully ind
286 The proposed methodology
was validated with a certified reference material TMDA-6
287 This methodology
was validated with a suspension of green alga Chlamydomo
288 lts from logic-gated flow cytometry analysis
was validated with bioinformatics-based analysis and mac
289 It
was validated with different sets of wine samples by com
290 The PLS model
was validated with external samples and presented good a
291 Such behaviour
was validated with fresh apple juice in which browning w
292 Specific and sensitive detection
was validated with isolates from clinical and environmen
293 The relationship with inflammation
was validated with multiple inflammatory markers measure
294 This system
was validated with the study of vanadium-based catalysts
295 A fast Endospore Germinability Assay (EGA)
was validated with traditional plate counts to enumerate
296 The performance of DVME
was validated with vapor pressure measurements of n-eico
297 The developed models
were validated with 131 samples produced outside the PDO
298 eported diagnostic or explorative biomarkers
were validated with a limit of quantification that was c
299 ion levels at the group and individual level
were validated with empirical impairment observed at lat
300 However, the IBD Disk has not
been validated yet in clinical practice.